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[Psychedelica bij de behandeling van psychiatrische aandoeningen anno 2025]. [2025年精神疾病治疗中的致幻剂]。
Q4 Medicine Pub Date : 2025-01-01
R E Blom, T Bostoen, O J N Bloemen, A E Schröder, J J Breeksema, M van Elk, W van den Brink, M Somers
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引用次数: 0
[The psychiatry residency program: looking 10 years ahead]. [精神病学住院医师项目:展望未来10年]。
Q4 Medicine Pub Date : 2025-01-01
D W Strijbos, A W Braam, P K H Deschamps, G Glas, U Klumpers

Background: Against the background of societal, technological and scientific developments, residency training programs anticipate changes in mental health care and its implications for the professional role of psychiatrists.

Aim: To sketch expected developments in (inter)national residency training programs in psychiatry the next ten years.

Method: Literature study and extrapolation of (inter)national plans regarding medical residency training programs.

Results: The next ten years we expect more emphasis on the following topics: a new balance between generalist and specialist medical competences and a shift towards more interdisciplinary learning, sustainable employability (‘lifelong learning’, psychological safety, professional balance), scientific education with a focus on translation and pluriformity, and international collaboration CONCLUSION: New (inter)national plans for residency programs in psychiatry aim to prepare psychiatrists to appropriately respond to the increasing societal demand for mental health care while keeping an eye on their own sustained employability.

背景:在社会、技术和科学发展的背景下,住院医师培训计划预测了精神卫生保健的变化及其对精神科医生职业角色的影响。目的:概述未来十年精神病学(国际)国家住院医师培训计划的预期发展。方法:文献研究与外推(国际)医师住院医师培训计划。结果:未来十年,我们预计将更加重视以下主题:通才和专科医学能力之间的新平衡,向更多跨学科学习的转变,可持续就业能力(终身学习,心理安全,专业平衡),注重翻译和多元化的科学教育,以及国际合作。新的(国际)精神病学住院医师计划旨在使精神科医生做好准备,以适当应对日益增长的社会对精神卫生保健的需求,同时密切关注他们自己的持续就业能力。
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引用次数: 0
[On the future relevance of mental health care for population mental health]. [论心理保健对人口心理健康的未来意义]。
Q4 Medicine Pub Date : 2025-01-01
P Bracke

Background: Opinions differ on the societal importance of mental health care (GGZ) and the direction it should take. Is there a need for prevention targeting high-risk health groups, should more attention be paid to precision psychiatry, or is the focus better placed on promoting a mentally healthy lifestyle or accessible care in disadvantaged neighborhoods?

Aim: To outline the social importance of mental health care from three perspectives: the biomedical-clinical approach, the moral-philosophical, social-critical perspective and an approach that emphasizes social inequality and disadvantage. Further I reflect on the possible importance of some innovations in mental health care for future general mental health.

Method: Literature review and consideration.

Results: Questions about the social importance of mental health care and the future direction of mental health care are typically viewed from a biomedical and clinical perspective, with the assumption that what benefits patients is also the most direct path to improved public mental health. However, other narratives also dominate the discussion, such as socio-critical approaches or perspectives emphasizing social inequality and marginalization.

Conclusion: Anyone who examines these approaches from a public health perspective must conclude that many innovations in mental health care are largely irrelevant to public mental health, despite their impact on the relationship between society and mental health care.

背景:关于精神卫生保健(GGZ)的社会重要性及其应采取的方向,意见不一。是否有必要针对高危健康群体进行预防,是否应该更多地关注精准精神病学,还是应该更好地将重点放在促进心理健康的生活方式或在弱势社区提供护理上?目的:从生物医学-临床角度、道德-哲学角度、社会批判角度和强调社会不平等和劣势的角度概述精神卫生保健的社会重要性。此外,我还思考了精神卫生保健方面的一些创新对未来一般精神卫生的可能重要性。方法:查阅文献并加以参考。结果:关于精神卫生保健的社会重要性和精神卫生保健的未来方向的问题通常是从生物医学和临床的角度来看待的,并假设使患者受益也是改善公众精神卫生的最直接途径。然而,其他叙述也主导了讨论,例如强调社会不平等和边缘化的社会批判方法或观点。结论:任何从公共卫生角度审视这些方法的人都必须得出这样的结论:尽管精神卫生保健方面的许多创新对社会与精神卫生保健之间的关系产生了影响,但它们在很大程度上与公众精神卫生无关。
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引用次数: 0
[Schroeder van der Kolk and Capgras's delusion]. [施罗德·范德科尔克和卡普格拉斯的妄想]。
Q4 Medicine Pub Date : 2025-01-01
H N Sno

Background: About one hundred years prior to Capgras' description of the eponymous misidentification psychosis, this clinical picture had already been described by Schroeder van der Kolk. To this day, this publication has received unjustly little attention.

Aim: To highlight Schroeder van der Kolk's case report and to bridge past and present, with emphasis on psychiatric care.

Method: Analysis of the original case history alongside Capgras' three publications and presentation of a modernized adaptation.

Results: The pathogenetic factors emphasized by Capgras - alienation, heightened affective tension, paranoid hypervigilance, and unconscious Oedipal conflicts - are also discernible in the patient described by Schroeder van der Kolk. His treatment strategy probably shows more similarities with contemporary psychiatric practice than might be expected.

Conclusion: The original case report can serve as a source of inspiration for the refinement of clinical intuition, functioning as a paper-based consultation.

背景:在Capgras描述与之同名的误诊精神病的大约一百年前,Schroeder van der Kolk已经描述了这种临床症状。直到今天,这本书还没有受到多少关注。目的:强调施罗德范德科尔克的病例报告,并将过去和现在联系起来,重点是精神病学护理。方法:分析原始病例史以及Capgras的三篇出版物,并提出一个现代化的改编。结果:Capgras强调的致病因素——异化、情感紧张加剧、偏执过度警觉和无意识的俄狄浦斯冲突——在Schroeder van der Kolk所描述的患者中也可以发现。他的治疗策略可能显示出与当代精神病学实践比预期更多的相似之处。结论:原始病例报告可作为改进临床直觉的灵感来源,具有纸质咨询的功能。
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引用次数: 0
[First episode psychosis associated with increased volume of an arachnoid cyst in the posterior fossa]. [首发精神病与后窝蛛网膜囊肿体积增大有关]。
Q4 Medicine Pub Date : 2025-01-01
L Van Buggenhout, F-L De Winter

We describe the case of a 64-year-old woman who experienced a first psychotic episode following an increase in volume of a known arachnoid cyst in the posterior fossa. This was associated with anxiety and panic attacks as well as mild cognitive deficits. A cystoperitoneal shunt was placed three years earlier to treat headaches, poor balance and memory problems associated with the cyst. Increasing the flow rate through the shunt, followed by the initiation of an SSRI, resulted in remission of the psychotic and affective symptoms. This case illustrates the potential association between structural infratentorial lesions, such as arachnoid cysts, and neuropsychiatric symptoms, particularly psychosis. Given that decompression of the cyst was associated with a reduction in symptoms, this suggests a link between the onset of psychotic symptoms and cerebellar dysfunction.

我们描述的情况下,64岁的妇女谁经历了第一次精神病发作后的体积增加,已知的蛛网膜囊肿在后窝。这与焦虑和恐慌发作以及轻度认知缺陷有关。三年前,为了治疗与囊肿相关的头痛、平衡能力差和记忆问题,他进行了膀胱腹腔分流术。通过分流增加流速,随后开始SSRI,导致精神病和情感症状的缓解。本病例说明了结构性幕下病变(如蛛网膜囊肿)与神经精神症状(特别是精神病)之间的潜在联系。鉴于囊肿减压与症状减轻相关,这表明精神病性症状的发作与小脑功能障碍之间存在联系。
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引用次数: 0
[Van onderbuik naar onderbouwd: psychometrie naar de klinische kern]. [从下腹部到腹部:心理测量到临床核心]。
Q4 Medicine Pub Date : 2025-01-01
N H Grootendorst
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引用次数: 0
[Trauma-focused and personality disorder treatment for posttraumatic stress disorder and comorbid cluster C personality disorder]. [创伤集中和人格障碍治疗创伤后应激障碍和共病型C型人格障碍]。
Q4 Medicine Pub Date : 2025-01-01
A van den End, A T F Beekman, J J M Dekker, K Thomaes

Background: Posttraumatic stress disorder (PTSD) is associated with high rates of avoidant, dependent and obsessive-compulsive personality disorders (cluster C-PD). It is unknown whether concurrent treatment for PTSD and comorbid cluster C-PD leads to superior treatment effects, compared to standalone trauma-focused treatment.

Aim: To test the efficacy of adding 52-58 sessions of PD treatment (group schema therapy; GST) to 12-18 sessions of individual trauma-focused treatment (imagery rescripting; ImRs).

Method: 130 adult outpatients were randomized to receive either ImRs or ImRs+GST. The main outcome was PTSD severity one year after start of treatment (CAPS-5). Secondary outcomes were cluster C-PD, psychiatric symptoms, quality of life, functioning, treatment response, remission, and dropout.

Results: At 12 months, there were large decreases in PTSD severity (d = 2,4), PD symptoms and all other secondary outcomes. There were no significant differences between conditions.

Conclusion: Large effects were observed in both treatment arms. The results suggests that trauma focused treatment is the preferred primary treatment in patients presenting with PTSD and comorbid cluster C-PD, after which more intensive psychotherapy aimed at the personality disorder may be considered in the case of residual personality disorder symptoms.

背景:创伤后应激障碍(PTSD)与回避型、依赖型和强迫性人格障碍(C-PD)的高发相关。目前尚不清楚同时治疗创伤后应激障碍和共病簇C-PD是否比单独治疗创伤更有效。目的:观察加组52 ~ 58次PD治疗的疗效;GST)到12-18次以创伤为重点的个人治疗(图像改写;imr)。方法:将130例成人门诊患者随机分为ImRs组和ImRs+GST组。主要结局是治疗开始一年后PTSD的严重程度(CAPS-5)。次要结局是C-PD组、精神症状、生活质量、功能、治疗反应、缓解和辍学。结果:在12个月时,创伤后应激障碍严重程度(d = 2,4)、PD症状和所有其他次要结局均大幅下降。不同条件之间没有显著差异。结论:两组疗效均显著。结果提示,创伤为重点的治疗是PTSD合并簇C-PD患者首选的主要治疗方法,在存在人格障碍残留症状的情况下,可考虑针对人格障碍进行更强化的心理治疗。
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引用次数: 0
[De behandelrelatie, verplichte zorg én de zoektocht naar perspectief]. [治疗关系、强制护理和寻找视角]。
Q4 Medicine Pub Date : 2025-01-01
S Berendsen
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引用次数: 0
[The organization of psychiatry in the Netherlands and Belgium: who is an example for whom?] [荷兰和比利时的精神病学组织:谁是谁的榜样?]]
Q4 Medicine Pub Date : 2025-01-01
K R Goethals, T Birkenhäger

Background: The medical profession such as that of a psychiatrist is a profession with three essential characteristics (specialist care, autonomy and formal recognition, and professional ethics). The 21st century is characterized by bureaucratization and marketization of healthcare. Medical sociologist Friedson described three forms of logic: the logic of the professional, the logic of bureaucracy and the logic of the market.

Aim: To test the position, autonomy and effectiveness of the psychiatrist from a historical perspective. To assess developments in Dutch and Belgian psychiatry and make a comparison.

Method: Two psychiatrists from Belgium and the Netherlands mention relevant developments. It is examined which form of logic is followed in these developments.

Results: The logic of the professional applies to quality and further training, but is threatened by some Boards of Directors and the position of the Dutch psychiatrist. The logic of bureaucracy dominates in the new legislation on compulsory healthcare in the Netherlands. Finally, the powerful health insurers illustrate the logic of the market.

Conclusion: The logics of bureaucracy and the market take the upper hand in the Netherlands, to the detriment of the logic of the professional. Extensive bureaucratization and the power of health insurers are not desirable developments for Belgium. Belgians should urgently consider the options for compulsory treatment and mandatory quality and further training.

背景:像精神科医生这样的医学职业是一个具有三个基本特征的职业(专科护理、自主和正式认可以及职业道德)。21世纪的医疗保健是以官僚化和市场化为特征的。医学社会学家弗里德森描述了三种形式的逻辑:专业逻辑、官僚逻辑和市场逻辑。目的:从历史的角度考察精神科医师的地位、自主性和有效性。评估荷兰和比利时精神病学的发展并进行比较。方法:来自比利时和荷兰的两名精神病学家提及相关进展。本文考察了在这些发展中所遵循的逻辑形式。结果:专业逻辑适用于素质和继续培训,但受到一些董事会和荷兰精神科医生职位的威胁。官僚主义的逻辑在荷兰强制性医疗保健的新立法中占主导地位。最后,强大的医疗保险公司说明了市场的逻辑。结论:在荷兰,官僚主义和市场的逻辑占了上风,损害了专业人士的逻辑。广泛的官僚化和医疗保险公司的权力对比利时来说是不可取的发展。比利时人应该紧急考虑强制治疗和强制质量和进一步培训的选择。
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引用次数: 0
[Psychiatric drug development on the verge of its Rubicon]. [精神科药物的发展处于绝境边缘]。
Q4 Medicine Pub Date : 2025-01-01
G Jacobs

Background: Recent reports from the psychiatric drug development space have been feeding the expectation of novel pharmacotherapies reaching the clinic over the next couple of years. In this context, advancement of novel compounds such as esketamine, KarXT, MDMA, daridorexant and psilocybine following decades of stagnation, is undoubtedly promising. However, complacency on the side of drug developers and psychiatrist should be considered premature.

Method: Discussion of literature, examples and backgrounds of drug development in psychiatry.

Results: After all, compared to neurology and oncology, psychiatry is lagging behind in terms of potential new drugs targeting truly novel mechanisms of action to treat psychiatric disorders. The current situation is conceptually related to 1) lacking an understanding of the pathophysiology of psychiatric disorders, 2) limited pharmacological characterization of novel drugs, 3) equating phenomenological diagnostic categories to diseases with a biological basis, and 4) the pharmaceutical industry aiming to introduce ‘blockbuster drugs’ to the market.

Conclusion: Altogether, psychiatric drug development is currently undergoing something of a renaissance, but relevant stakeholders seem unable to address the shortcomings and pitfalls of the current approach, risking psychiatric drug development to fall even further behind. Improving drug development in psychiatry is only possible if clinicians, researchers, drug developers and regulators join forces in a concerted effort to address these issues.

背景:最近来自精神科药物开发领域的报告已经满足了对未来几年进入临床的新型药物治疗的期望。在这种背景下,艾氯胺酮、KarXT、MDMA、daridorexant和裸盖菇碱等新型化合物在停滞数十年后的发展无疑是有希望的。然而,药物开发人员和精神科医生的沾沾自喜还为时过早。方法:讨论精神病学药物开发的文献、实例和背景。结果:毕竟,与神经病学和肿瘤学相比,精神病学在潜在的针对真正新颖的作用机制的新药治疗精神疾病方面是落后的。目前的状况在概念上与以下因素有关:1)缺乏对精神疾病病理生理学的理解;2)新药的药理学表征有限;3)将现象学诊断类别等同于具有生物学基础的疾病;4)制药行业旨在推出重头药;去市场。结论:总的来说,精神科药物的开发目前正在经历某种复兴,但相关的利益相关者似乎无法解决当前方法的缺点和陷阱,这有可能使精神科药物的开发进一步落后。只有临床医生、研究人员、药物开发人员和监管机构共同努力解决这些问题,才能改善精神病学的药物开发。
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引用次数: 0
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Tijdschrift voor psychiatrie
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