Indole Acetic Acid (IAA) is the important phytohormone for boosting plant-growth promotion. It is related with amino acid tryptophan as a precursor for building IAA. However some bacteria such as Bacillus sp. and Escherichia coli enable to produce IAA without L-tryptophan on culture medium via the tryptophan independent pathways. This study aims to determine the potential of indigenous Bacillus sp. and E. coli isolate in producing IAA via Trp-independent pathways (without L- tryptophan). The stage of this study consists of growing of isolate on liquid media without tryptophan and measuring the levels of IAA using Salkowsky method. Bacillus sp and Escherichia coli could produce IAA with the concentration of 0,0236 mmol/L and 0,024 mmol/L, respectively. The concentration of IAA produced by these bacteria is quite low because of their ability to synthesis IAA from the independent tryptophan pathway. The independent tryptophan pathway means these bacteria could synthesize IAA without using tryptophan as a precursor on their growth medium. n
{"title":"UJI POTENSI Bacillus sp. DAN Escherichia coli DALAM MENGHASILKAN INDOLE ACETIC ACID (IAA) TANPA MENGGUNAKAN TRIPTOFAN PADA MEDIA PERTUMBUHAN","authors":"M. Asril","doi":"10.35472/281434","DOIUrl":"https://doi.org/10.35472/281434","url":null,"abstract":"Indole Acetic Acid (IAA) is the important phytohormone for boosting plant-growth promotion. It is related with amino acid tryptophan as a precursor for building IAA. However some bacteria such as Bacillus sp. and Escherichia coli enable to produce IAA without L-tryptophan on culture medium via the tryptophan independent pathways. This study aims to determine the potential of indigenous Bacillus sp. and E. coli isolate in producing IAA via Trp-independent pathways (without L- tryptophan). The stage of this study consists of growing of isolate on liquid media without tryptophan and measuring the levels of IAA using Salkowsky method. Bacillus sp and Escherichia coli could produce IAA with the concentration of 0,0236 mmol/L and 0,024 mmol/L, respectively. The concentration of IAA produced by these bacteria is quite low because of their ability to synthesis IAA from the independent tryptophan pathway. The independent tryptophan pathway means these bacteria could synthesize IAA without using tryptophan as a precursor on their growth medium.\u0000n","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127112257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract—In Indonesia the numbers of orthopaedic surgeons are still not able to cover all demand. Badan Pusat Statistik (2015) reported that there are merely two orthopaedic surgeons in Lampung province having to serve about 8.117.268 people. Meanwhile, based on Ministry of Health of Republic of Indonesia, the ideal ratio between doctor and people is 12.2 doctor for each 100.000 people. Besides that, sometimes the surgeons need to serve more than one medical facility. Consequently, the patients might feel unpleasant. The lack of human resources becomes the main reason for developing expert system for diagnosing orthopaedic diseases. The expert system is able to diagnose orthopaedic diseases as well as fracture, dislocation, osteoarthritis and osteoporosis. The system is developed by using forward chaining methodology. This methodology is suitable for identifying a disease based on their symptoms. The result shows that the expert can answer 45 % of questions by identifying 6 main symptoms without continuing to following symptom questions.
在印度尼西亚，整形外科医生的数量仍然不能满足所有的需求。Badan Pusat statistics(2015)报告称，楠榜省只有两名整形外科医生，却要服务大约8.117.268人。同时，根据印度尼西亚共和国卫生部的数据，医生与人之间的理想比例是每10万人12.2名医生。除此之外，有时外科医生需要服务于多个医疗机构。因此，患者可能会感到不愉快。人力资源的缺乏成为骨科疾病诊断专家系统开发的主要原因。该专家系统能够诊断骨科疾病以及骨折、脱位、骨关节炎和骨质疏松症。该系统采用前向链方法开发。这种方法适用于根据症状确定疾病。结果表明，专家可以通过识别6个主要症状来回答45%的问题，而无需继续遵循症状问题。
{"title":"PEMBANGUNAN SISTEM PAKAR UNTUK DIAGNOSIS PENYAKIT TULANG DAN SENDI","authors":"Hafiz Budi Firmansyah","doi":"10.35472/281487","DOIUrl":"https://doi.org/10.35472/281487","url":null,"abstract":"Abstract—In Indonesia the numbers of orthopaedic surgeons are still not able to cover all demand. Badan Pusat Statistik (2015) reported that there are merely two orthopaedic surgeons in Lampung province having to serve about 8.117.268 people. Meanwhile, based on Ministry of Health of Republic of Indonesia, the ideal ratio between doctor and people is 12.2 doctor for each 100.000 people. Besides that, sometimes the surgeons need to serve more than one medical facility. Consequently, the patients might feel unpleasant. The lack of human resources becomes the main reason for developing expert system for diagnosing orthopaedic diseases. The expert system is able to diagnose orthopaedic diseases as well as fracture, dislocation, osteoarthritis and osteoporosis. The system is developed by using forward chaining methodology. This methodology is suitable for identifying a disease based on their symptoms. The result shows that the expert can answer 45 % of questions by identifying 6 main symptoms without continuing to following symptom questions.","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"5 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113941615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
nn Energy surya yang merupakan salah satu sumber energy terbarukan yang dapat dijadikan sebagai alternatif yang fleksibel digunakan untuk penyediaan listrik di Indonesia. Daerah Lampung memiliki potensi energi surya rata-rata 4,43 kWh/m2/hari dengan variasi bulanan sekitar 7 persen. Lampung juga dinyatakan cocok untuk aplikasi teknologi energi surya fotovoltaik karena memiliki karakteristik komponen radiasi langsung yang lebih dominan daripada komponen radiasi baurnya. Institut Teknologi Sumatra (ITERA) dalam perkembangannya sangat membutuhkan peningkatan pasokan energi listrik setiap tahunnya. Sehingga perlu lirikan akan energi lain sebagai dukungan dalam mewujudkann forest kampus dan pemenuhan energi. Untuk mengetahui potensi energy surya di lingkungan ITERA, maka dilakukanlah study awal energy surya yang dapat diproduksi. Tujuannya adalah agar didapat informasi potensi yang real untuk perkiraan pengembangan energy surya di lingkungan Institut. Pengukuran potensi ini menggunakan rangkaian panel surya yang disambung ke beban Resistor dan lampu yang diatur maksimum. Kemudian dihitung nilai Daya yang didapat dari pengukuran arus dan tegangannya. Dari hasil pengukuran diperoleh bahwa intensitas sinar matahari tinggi terjadi pada pukul 09.00-15.00 dengan daya luaran mencapai 109W.
{"title":"A Studi Awal Potensi Energi Surya Wilayah Lampung","authors":"Kiki Kananda","doi":"10.35472/281417","DOIUrl":"https://doi.org/10.35472/281417","url":null,"abstract":"nn Energy surya yang merupakan salah satu sumber energy terbarukan yang dapat dijadikan sebagai alternatif yang fleksibel digunakan untuk penyediaan listrik di Indonesia. Daerah Lampung memiliki potensi energi surya rata-rata 4,43 kWh/m2/hari dengan variasi bulanan sekitar 7 persen. Lampung juga dinyatakan cocok untuk aplikasi teknologi energi surya fotovoltaik karena memiliki karakteristik komponen radiasi langsung yang lebih dominan daripada komponen radiasi baurnya. Institut Teknologi Sumatra (ITERA) dalam perkembangannya sangat membutuhkan peningkatan pasokan energi listrik setiap tahunnya. Sehingga perlu lirikan akan energi lain sebagai dukungan dalam mewujudkann forest kampus dan pemenuhan energi. Untuk mengetahui potensi energy surya di lingkungan ITERA, maka dilakukanlah study awal energy surya yang dapat diproduksi. Tujuannya adalah agar didapat informasi potensi yang real untuk perkiraan pengembangan energy surya di lingkungan Institut. Pengukuran potensi ini menggunakan rangkaian panel surya yang disambung ke beban Resistor dan lampu yang diatur maksimum. Kemudian dihitung nilai Daya yang didapat dari pengukuran arus dan tegangannya. Dari hasil pengukuran diperoleh bahwa intensitas sinar matahari tinggi terjadi pada pukul 09.00-15.00 dengan daya luaran mencapai 109W.","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134507624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liquefied Natural Gas (LNG) is one of the potential alternative fuels to replace conventional fuels. Using LNG as fuel in Indonesia especially Yogyakarta will give many advantages, for instance, reduced greenhouse gas emissions so that eco-city in Yogyakarta can be realized. Although LNG has many advantages, LNG still contains many hazards whether during storage or distribution, the major hazard is radiant heat. This study aims to analyze and simulate hazard scenarios when transporting LNG such as fire pools, fireballs and vapor clouds and establishing exclusion zone by Areal Location of Hazardous Atmospheres (ALOHA) simulation. This study assumes that the diameter of the tank leak is 1 in and 3 in. The simulation results the exclusion zone from pool fire’s heat radiation from 1 in and 3 in leaks are more than 14 m and 39 m. While the safe distance of the fireball is 799 m. While in the distance vapor clouds that have a possibility of fire for the diameter leakage of 1 and 3 in are 21 m and 59 m.
{"title":"Skenario konsekuensi analisis pengangkutan LNG Semarang-Yogyakarta dengan simulasi ALOHA","authors":"Didik Supriyadi","doi":"10.35472/281478","DOIUrl":"https://doi.org/10.35472/281478","url":null,"abstract":"Liquefied Natural Gas (LNG) is one of the potential alternative fuels to replace conventional fuels. Using LNG as fuel in Indonesia especially Yogyakarta will give many advantages, for instance, reduced greenhouse gas emissions so that eco-city in Yogyakarta can be realized. Although LNG has many advantages, LNG still contains many hazards whether during storage or distribution, the major hazard is radiant heat. This study aims to analyze and simulate hazard scenarios when transporting LNG such as fire pools, fireballs and vapor clouds and establishing exclusion zone by Areal Location of Hazardous Atmospheres (ALOHA) simulation. This study assumes that the diameter of the tank leak is 1 in and 3 in. The simulation results the exclusion zone from pool fire’s heat radiation from 1 in and 3 in leaks are more than 14 m and 39 m. While the safe distance of the fireball is 799 m. While in the distance vapor clouds that have a possibility of fire for the diameter leakage of 1 and 3 in are 21 m and 59 m.","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132178960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The optimization of extraction procces for Sirih Hijau leaves (Piper betle L.) have been attempted. The aim of the research was to knowing the influence and the ratio of total yield on two different methods, that was using maceration and reflux method and followed by microbial antibacterial by microdilution test to show the qualitative value of MIC percentage of Sirih Hijau leaves extract against Escherichia coli and Staphylococcus aureus bacteria. The analysis was conducted descriptively for subsequent use as a basis to determined MIC percentage quantitatively. The result of extraction with two methods showed that the highest yield was yielded in reflux process with 18.5% rendement value with the weight ratio of 1: 5 to the maceration process. Phytochemical screening shows the ethanol extract of Sirih Hijau leaves contains flavonoid, saponins, and tannins compounds that have activated as antibacterial. The results of microbial antibacterial testing showed MIC percentage in Staphylococcus aureus at 5% and Eschericia coli at 3%. The test results indicate that Sirih HIjau leaves (Piper betle L.) have potential as an antibacterial candidate. Keyword : Sirih Hijau, reflux, maceration, antibacterial, microdilution
{"title":"PERBANDINGAN TOTAL RENDEMEN DAN SKRINING ANTIBAKTERI EKSTRAK ETANOL DAUN SIRIH HIJAU (Piper betle L.) SECARA MIKRODILUSI","authors":"R. Vifta","doi":"10.35472/281450","DOIUrl":"https://doi.org/10.35472/281450","url":null,"abstract":"The optimization of extraction procces for Sirih Hijau leaves (Piper betle L.) have been attempted. The aim of the research was to knowing the influence and the ratio of total yield on two different methods, that was using maceration and reflux method and followed by microbial antibacterial by microdilution test to show the qualitative value of MIC percentage of Sirih Hijau leaves extract against Escherichia coli and Staphylococcus aureus bacteria. The analysis was conducted descriptively for subsequent use as a basis to determined MIC percentage quantitatively. \u0000The result of extraction with two methods showed that the highest yield was yielded in reflux process with 18.5% rendement value with the weight ratio of 1: 5 to the maceration process. Phytochemical screening shows the ethanol extract of Sirih Hijau leaves contains flavonoid, saponins, and tannins compounds that have activated as antibacterial. The results of microbial antibacterial testing showed MIC percentage in Staphylococcus aureus at 5% and Eschericia coli at 3%. The test results indicate that Sirih HIjau leaves (Piper betle L.) have potential as an antibacterial candidate. \u0000 \u0000Keyword : Sirih Hijau, reflux, maceration, antibacterial, microdilution","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123287441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rinda Gusvita, Dian Fajarika, Mika Margareta, Devia Gahana Ca
Management of feedlot manure is becoming a larger responsibility as more regulations are imposed to protect water, both surface and groundwater, from manure contamination. Instead of using the manure for compost, feedlot owners can capture methane from the decomposing manure (and turn that into electricity or heat), or use the waste to produce liquid fuel. Biogas may also be called renewable natural gas because biogas can be used as a fuel source to produce electricity and heat like natural gas.This research converting energy generated from the measurement of total waste theoretically to be convert to electricity generated from the waste. Within the number of 19,398 total cows in Jati Agung Sub District husbandry has the potential to produce electric energy of 149,365.376 kwh per day or 15,836.79 mwh per year. The conversion from waste to electricity will reduce the number of total emission of 64,086.7464 tCO2 per year.
{"title":"Analisis Potensi Energi dan Pengurangan Emisi Co2 dengan Pengelolaan Limbah Peternakan Sapi Rakyat di Kecamatan Jati Agung Kabupaten Lampung Selatan","authors":"Rinda Gusvita, Dian Fajarika, Mika Margareta, Devia Gahana Ca","doi":"10.35472/281424","DOIUrl":"https://doi.org/10.35472/281424","url":null,"abstract":"Management of feedlot manure is becoming a larger responsibility as more regulations are imposed to protect water, both surface and groundwater, from manure contamination. Instead of using the manure for compost, feedlot owners can capture methane from the decomposing manure (and turn that into electricity or heat), or use the waste to produce liquid fuel. Biogas may also be called renewable natural gas because biogas can be used as a fuel source to produce electricity and heat like natural gas.This research converting energy generated from the measurement of total waste theoretically to be convert to electricity generated from the waste. Within the number of 19,398 total cows in Jati Agung Sub District husbandry has the potential to produce electric energy of 149,365.376 kwh per day or 15,836.79 mwh per year. The conversion from waste to electricity will reduce the number of total emission of 64,086.7464 tCO2 per year.","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122157248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A total of 26.6% of the population in Lampung Province consume traditional medicine, one of which is Jamu Pegal Linu. However, a large public interest in herbal products is often misused by herbal manufacturers that it is possible to add BKO (Medicinal Chemicals), such as dexamethasone.The purpose of this study is to identify the presence or absence of dexamethasone in the preparation of Jamu Pegal Linu. The samples are taken from the store and depot herbs contained in the Markets of Bandar Lampung, acquired three different brands. The method used is Thin Layer Chromatography using dikloretan motion: diethyl ether: methanol: water (77:15: 8: 1,2) as a mobile phase which are non-polar, and silica gel GF 254nm as a stationary phase. The result showed that the detection of three samples of Jamu Pegal Linu contained staining purple and the difference of Rf sample with reference standard on the first repetition is 0.46, 0.44, 0.47, and on the second repetition is 0.45, 0.45 and 0.48, which are ≥ 0.05. It can be concluded that the sample of Jamu Pegal Linu in Bandar Lampung 0% containing dexamethasone.
{"title":"Identifikasi Deksametason dalam Jamu Pegal Linu Sediaan Serbuk yang Beredar di Pasar-pasar Kota Bandar Lampung secara Kromatografi Lapis Tipis","authors":"Sudewi Mukaromah Khoirunnisa","doi":"10.35472/281467","DOIUrl":"https://doi.org/10.35472/281467","url":null,"abstract":"A total of 26.6% of the population in Lampung Province consume traditional medicine, one of which is Jamu Pegal Linu. However, a large public interest in herbal products is often misused by herbal manufacturers that it is possible to add BKO (Medicinal Chemicals), such as dexamethasone.The purpose of this study is to identify the presence or absence of dexamethasone in the preparation of Jamu Pegal Linu. The samples are taken from the store and depot herbs contained in the Markets of Bandar Lampung, acquired three different brands. The method used is Thin Layer Chromatography using dikloretan motion: diethyl ether: methanol: water (77:15: 8: 1,2) as a mobile phase which are non-polar, and silica gel GF 254nm as a stationary phase. The result showed that the detection of three samples of Jamu Pegal Linu contained staining purple and the difference of Rf sample with reference standard on the first repetition is 0.46, 0.44, 0.47, and on the second repetition is 0.45, 0.45 and 0.48, which are ≥ 0.05. It can be concluded that the sample of Jamu Pegal Linu in Bandar Lampung 0% containing dexamethasone.","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128989657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reaktor Serba Guna G.A Siwabessy (RSG-GAS) was built since 1983. RSG-GAS is a type of research reactor equipped with heat carrier and cooling system which serves to remove heat arising from fission reactions. In the heat carrier medium, the reactor equipped with a secondary cooling system using water originating from PAM Puspiptek. Water used in secondary cooling systems can cause some major problems of crust, corrosion, and moss or microorganisms. In this research, the phosphorus (orthophosphate), zinc, and conductivity and pH in the secondary cooling system have been measured to determine whether or not the flow rate of the injection system is used. Determination of concentration of the elements was performed using a DR / 2400 spectrophotometer portable device with ZincoVer 5 Powder Pillow reagent, cyclohexane for zinc concentration, and PhosVer 3 phophate for phosphorus concentration. From the results obtained, the overall flow rate of injector injection of 1.7 L / h gives a good result. Significant differences occurred only in conductivity values dated July 21, 2009 both in piped water and cooling towers exceeding 950 μs / cm. And the value of orthophosphate concentration dated August 4, 2009 that exceeds 10 ppm.
{"title":"STUDI SISTEM INJEKSI INHIBITOR KOROSI TERHADAP KANDUNGAN ORTHOFOSFAT DAN SENG SEBAGAI PARAMETER KENDALI KOROSI PADA SISTEM PENDINGIN SEKUNDER RSG-GAS","authors":"Edwin Rizki Safitra","doi":"10.35472/281485","DOIUrl":"https://doi.org/10.35472/281485","url":null,"abstract":"Reaktor Serba Guna G.A Siwabessy (RSG-GAS) was built since 1983. RSG-GAS is a type of research reactor equipped with heat carrier and cooling system which serves to remove heat arising from fission reactions. In the heat carrier medium, the reactor equipped with a secondary cooling system using water originating from PAM Puspiptek. Water used in secondary cooling systems can cause some major problems of crust, corrosion, and moss or microorganisms. In this research, the phosphorus (orthophosphate), zinc, and conductivity and pH in the secondary cooling system have been measured to determine whether or not the flow rate of the injection system is used. Determination of concentration of the elements was performed using a DR / 2400 spectrophotometer portable device with ZincoVer 5 Powder Pillow reagent, cyclohexane for zinc concentration, and PhosVer 3 phophate for phosphorus concentration. From the results obtained, the overall flow rate of injector injection of 1.7 L / h gives a good result. Significant differences occurred only in conductivity values dated July 21, 2009 both in piped water and cooling towers exceeding 950 μs / cm. And the value of orthophosphate concentration dated August 4, 2009 that exceeds 10 ppm.","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130487920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Conventional drug delivery systems have a shorter residence time in the stomach that causes less optimal drug absorption, the presence of food in the stomach also affects the absorption of the drug in the gastrointestinal tract so that it takes a drug that can stay and last longer in the stomach without being affected by the emptying process Stomach. In this study beads preparations are made that can stay and float so that lasts longer in the stomach. Alginate-containing beads are formulated by gelation method in which the alginate solution is dropped into a calcium chloride solution to form beads. The effects of oil type and alginate on morphological forms and buoyancy characteristics have been optimized. Beads containing alginate and paraffin can float on a gastric medium simulation for 240 minutes. The presence of paraffins can maintain the integrity and release of alginate beads during contact with the gastric medium. The SEM results describe the paraffin forming globules on the entire surface of the beads. Beads also show the ability to be able to float depending on the concentration of paraffin used.
{"title":"Pembuatan sediaan beads alginat dengan metode gelasi ion yang dapat mengapung di lambung","authors":"Nur Adliani","doi":"10.35472/281469","DOIUrl":"https://doi.org/10.35472/281469","url":null,"abstract":"Conventional drug delivery systems have a shorter residence time in the stomach that causes less optimal drug absorption, the presence of food in the stomach also affects the absorption of the drug in the gastrointestinal tract so that it takes a drug that can stay and last longer in the stomach without being affected by the emptying process Stomach. In this study beads preparations are made that can stay and float so that lasts longer in the stomach. Alginate-containing beads are formulated by gelation method in which the alginate solution is dropped into a calcium chloride solution to form beads. The effects of oil type and alginate on morphological forms and buoyancy characteristics have been optimized. Beads containing alginate and paraffin can float on a gastric medium simulation for 240 minutes. The presence of paraffins can maintain the integrity and release of alginate beads during contact with the gastric medium. The SEM results describe the paraffin forming globules on the entire surface of the beads. Beads also show the ability to be able to float depending on the concentration of paraffin used.","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126935973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rangka Terbreis Eksentris (RTE) merupakan sistem bangunan tahan gempa yang mempunyai keunggulan dari segi kekuatan dan kekakuan serta mempunyai daktilitas dan kemampuan energi disipasi yang baik dalam kondisi inelastis. Link adalah elemen penting yang berfungsi untuk mendisipasikan energi gempa melalui perilaku inelastis struktur. Kinerja link geser berupa kekuatan, kekakuan, daktilitas dan disipasi energi tergantung pada profil penampang yang digunakan pada link. Kajian ini bertujuan untuk mengetahui perilaku struktur RTE dengan link menggunakan sambungan baut yang menggunakan variasi mutu baja serta pelebaran ujung pelat sayap (Side Extended Plate/SEP) dan tanpa SEP. Analisis dilakukan dengan menggunakan menggunakan software MSC PATRAN/NASTRAN. Sebanyak 8 (delapan) variasi model link dikaji untuk menentukan kinerja struktur yang paling optimum ketika dilakukan pembebanan statik monotonik dan siklik dengan kontrol perpindahan. Hasil menunjukkan bahwa variasi mutu baja link pada pelat sayap dan pelat badan dapat meningkatkan kekuatan, kekakuan, dan daktilitas struktur secara signifikan dibandingkan dengan penggunaan SEP. Kata kunci : Rangka Terbreis Eksentis (RTE), link geser, link sambungan baut dan las, variasi mutu baja, pelebaran pelat sayap
{"title":"KAJIAN NUMERIK STRUKTUR RANGKA TERBREIS EKSENTRIK DENGAN LINK YANG DAPAT DIGANTI","authors":"N. B. Wirawan","doi":"10.35472/281452","DOIUrl":"https://doi.org/10.35472/281452","url":null,"abstract":"Rangka Terbreis Eksentris (RTE) merupakan sistem bangunan tahan gempa yang mempunyai keunggulan dari segi kekuatan dan kekakuan serta mempunyai daktilitas dan kemampuan energi disipasi yang baik dalam kondisi inelastis. Link adalah elemen penting yang berfungsi untuk mendisipasikan energi gempa melalui perilaku inelastis struktur. Kinerja link geser berupa kekuatan, kekakuan, daktilitas dan disipasi energi tergantung pada profil penampang yang digunakan pada link. Kajian ini bertujuan untuk mengetahui perilaku struktur RTE dengan link menggunakan sambungan baut yang menggunakan variasi mutu baja serta pelebaran ujung pelat sayap (Side Extended Plate/SEP) dan tanpa SEP. Analisis dilakukan dengan menggunakan menggunakan software MSC PATRAN/NASTRAN. Sebanyak 8 (delapan) variasi model link dikaji untuk menentukan kinerja struktur yang paling optimum ketika dilakukan pembebanan statik monotonik dan siklik dengan kontrol perpindahan. Hasil menunjukkan bahwa variasi mutu baja link pada pelat sayap dan pelat badan dapat meningkatkan kekuatan, kekakuan, dan daktilitas struktur secara signifikan dibandingkan dengan penggunaan SEP. \u0000 \u0000Kata kunci : Rangka Terbreis Eksentis (RTE), link geser, link sambungan baut dan las, variasi mutu baja, pelebaran pelat sayap","PeriodicalId":231292,"journal":{"name":"Journal on Satisfiability, Boolean Modeling and Computation","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131625974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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