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Phenytoin attenuates seizure severity and hippocampal derangement more than levetiracetam or phenytoin-levetiracetam adjunctive treatment in electrically-convulsed male BALB/c Mice 在电惊厥雄性BALB/c小鼠中,苯妥英比左乙拉西坦或苯妥英-左乙拉西坦辅助治疗更能减轻癫痫发作严重程度和海马紊乱
Pub Date : 2023-05-29 DOI: 10.4314/tjhc.v30i2.4
O. Osuntokun, G. Olayiwola, K. I. Adedokun, O. O. Oladokun, T. Abayomi, A. Ayoka
No Abstract
没有抽象的
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引用次数: 0
Reported morbidities, Blood pressure pattern and Body Mass Index of Informal Caregivers of Hospitalised Patients in a tertiary health facility in Nigeria 尼日利亚三级医疗机构住院病人非正式护理人员报告的发病率、血压模式和体重指数
Pub Date : 2023-05-29 DOI: 10.4314/tjhc.v30i2.2
M. Fasiku, O. Akande, O. A. Bolarinwa, T. Akande
No Abstract
没有抽象的
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引用次数: 0
Melatonin Mitigates Hormonal Toxicity in Cannabis -Treated Female Wistar Rats 褪黑素减轻大麻处理雌性Wistar大鼠的激素毒性
Pub Date : 2023-05-29 DOI: 10.4314/tjhc.v30i2.3
A. Oluwasola, O. Ayoola, Garba Saa'du, M. Adepoju, S. Biliaminu, L. Olayaki
No Abstract
没有抽象的
{"title":"Melatonin Mitigates Hormonal Toxicity in Cannabis -Treated Female Wistar Rats","authors":"A. Oluwasola, O. Ayoola, Garba Saa'du, M. Adepoju, S. Biliaminu, L. Olayaki","doi":"10.4314/tjhc.v30i2.3","DOIUrl":"https://doi.org/10.4314/tjhc.v30i2.3","url":null,"abstract":"No Abstract","PeriodicalId":23292,"journal":{"name":"Tropical Journal of Health Sciences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74237328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the pathological pattern of Knee aches and injuries in Northwestern Nigeria: the role of Magnetic Resonance Imaging 评估尼日利亚西北部膝关节疼痛和损伤的病理模式:磁共振成像的作用
Pub Date : 2023-05-29 DOI: 10.4314/tjhc.v30i2.1
S. Lawal, M. Z. Ibrahim, M. Musa, A. Abubakar, I. Aliyu, A. Adamu
No Abstract
没有抽象的
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引用次数: 0
Molecular detection of Human Rhinovirus Infection among Children with Respiratory infection attending University of Ilorin Teaching Hospital, Ilorin, Nigeria 尼日利亚伊洛林大学教学医院呼吸道感染患儿鼻病毒感染的分子检测
Pub Date : 2023-05-29 DOI: 10.4314/tjhc.v30i2.5
M. Odebisi-Omokanye, M. K. Sulaiman, K.O. Maiyaki, D.Y. Diryilmwa
No Abstract
没有抽象的
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引用次数: 0
Review of Indications for Pacemaker insertion in Cardiac Patients 心脏病人心脏起搏器插入适应症综述
Pub Date : 2023-05-29 DOI: 10.4314/tjhc.v30i2.6
K. Uwanuruochi, R. A. Shah
No Abstract.
没有抽象的。
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引用次数: 0
Serological prevalence and predictors of Hepatitis B infection among Adult Patients attending Out-Patient Clinic, General Hospital, Ilorin Kwara State Nigeria. 尼日利亚伊洛林Kwara州综合医院门诊成年患者乙型肝炎感染的血清学患病率和预测因素
Pub Date : 2023-04-26 DOI: 10.4314/tjhc.v30i1.4
C. Ademola, A. R. Yusuf, I. Obalowu, A. Mohammed, O. Oyeleke, A. Alabi
Hepatitis B is a viral infection that is ravaging sub-Sahara African countries including Nigeria.  Several studies have been done on hepatitis B infection among different population groups including pregnant women, blood donors and children but very few have reported findings among primary care adult patients. The aim of this study was to determine the prevalence of hepatitis B infection among the primary care patients and the possible associated risk factors. It was a hospital-based descriptive cross-sectional study done among adults attending out-patient clinic of the General Hospital Ilorin. A sample size of 338 was estimated with the use of EPI-info 7 statistical software and Enzyme-based immunoassay testing was used to screen for hepatitis B virus infection among the study participants. The sero-prevalence of hepatitis B infection among the study population was 14.5%. Identified risk factors associated with hepatitis B infection in this study were family history of hepatitis B infection, blood transfusion and unsupervised home delivery. In conclusion, the findings in this study have shown that hepatitis B infection was highly endemic among adult primary care patients. Blood transfusion and unsupervised home deliveries were the predictors of hepatitis B infection among these study participants.
乙型肝炎是一种病毒感染,正在包括尼日利亚在内的撒哈拉以南非洲国家肆虐。已经对不同人群(包括孕妇、献血者和儿童)的乙型肝炎感染进行了几项研究,但很少有报告在初级保健成人患者中发现的结果。本研究的目的是确定初级保健患者中乙型肝炎感染的患病率和可能的相关危险因素。这是一项基于医院的描述性横断面研究,在伊洛林综合医院门诊的成年人中进行。使用EPI-info 7统计软件估计样本量为338人,并使用酶免疫测定法筛查研究参与者中的乙型肝炎病毒感染。研究人群中乙型肝炎感染的血清患病率为14.5%。本研究确定的与乙型肝炎感染相关的危险因素是乙型肝炎感染家族史、输血和无人监护的家庭分娩。总之,本研究结果表明,乙型肝炎感染在成人初级保健患者中高度流行。在这些研究参与者中,输血和无人监督的家庭分娩是乙型肝炎感染的预测因素。
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引用次数: 0
Autoimmune Hepatitis Presenting as Acute Fulminant Hepatitis in a Nigerian Woman 自身免疫性肝炎表现为急性暴发性肝炎在尼日利亚妇女
Pub Date : 2023-04-26 DOI: 10.4314/tjhc.v30i1.5
K. Akande, T. Fakoya, O. Balogun, A. M. Osundina, T. Oke, A. Akere, A. Aje, S. Ola, J. Otegbayo
Autoimmune hepatitis is rare in sub-Saharan Africa except for south Africa. Only 3 cases have been previously reported in Nigeria with a population of 200 million. All the 3 cases had features of liver cirrhosis at presentation. We report a case of a 49-year-old woman who presented with acute fulminant hepatitis and turned out to be autoimmune hepatitis based on elevated serum gammaglobinaemia, amino transferases, positive anti-nuclear antibody, and absence of other aetiology. Patient had a good response to steroid treatment. Autoimmune hepatitis occurs in Nigerian patients and can present in a rarer form of acute fulminant hepatitis which seen in about 10% of cases globally.
除南非外,自身免疫性肝炎在撒哈拉以南非洲很少见。在拥有2亿人口的尼日利亚,以前仅报告了3例病例。3例患者均有肝硬化的表现。我们报告一例49岁的女性,她表现为急性暴发性肝炎,结果是自身免疫性肝炎,基于血清γ -球蛋白血症升高,氨基转移酶,抗核抗体阳性,没有其他病因。病人对类固醇治疗反应良好。自身免疫性肝炎发生在尼日利亚患者中,可表现为一种罕见的急性暴发性肝炎,在全球约10%的病例中可见。
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引用次数: 0
A Multiregional Survey of Serum Vitamin D Levels among apparently healthy Nigerians – Prevalence and Risk Factors of Hypovitaminosis D 尼日利亚人血清维生素D水平的多地区调查——维生素D缺乏症的患病率和危险因素
Pub Date : 2023-04-25 DOI: 10.4314/tjhc.v30i1.1
M. Abubakar, S. Idris, O. Quadri, J. Yusuff, S. Biliaminu, S. Mohammad, O. Afolabi, H. Omokanye, N.A Bemu, O. Wuraola, Waliu Oladosu, S. Adamu, N. Iyanda, N.A. Shofoluwe, J. Lawal, W. Omotosho
Globally, Hypovitaminosis D has been reported across age groups, with predisposing factors such as black race, older age, inactivity, diet, lack of vitamin D supplementation, indoor-outdoor lifestyle, winter/ wet season and sociocultural/socioeconomic factors. Vitamin D is an essential fat-soluble vitamin with a significant contribution to human health. The optimal level of serum vitamin D for adults' general health may be between 75 and 100 nmol/L, while there are sparse outcome data to help define a healthy or optimal level in children. In spite of the consideration for a serum vitamin D level below 25nmol/l as the lowest cutoff for vitamin D status, there are pieces of evidence that rickets can occur in infants and young children with a serum vitamin D concentration that is higher than 25nmol/l.  The study aimed to determine the prevalence and risk factors of hypovitaminosis D among apparently healthy Nigerian hospital workers and patients' caregivers and possibly provide a rationale for clinical supplementation. It was a descriptive, cross-sectional multicentre study conducted in 198 participants from the three geopolitical zones of the country between January 2019 and March 2019. A multistage sampling method was used to select the geopolitical zones and tertiary hospitals in the country while a simple random sampling method was used to select the participants from each zones. Serum vitamin D level was determined by Calbiotech Inc, kit. Over 68% of the participants had sufficient serum vitamin D levels while 30.8% had low levels, with the latter constituting the prevalence of hypovitaminosis D in this study. Only one participant had a toxic serum level of vitamin D. This study shows that about a third of the sample population had Hypovitaminosis D. This suggests a need for routine vitamin D estimation and supplementation accordingly among blacks.
在全球范围内,维生素D缺乏症在各个年龄组中都有报道,其易感因素包括黑人种族、年龄较大、缺乏活动、饮食、缺乏维生素D补充、室内外生活方式、冬季/潮湿季节以及社会文化/社会经济因素。维生素D是一种重要的脂溶性维生素,对人体健康有重要贡献。成人总体健康的最佳血清维生素D水平可能在75至100 nmol/L之间,而对于儿童来说,没有足够的结果数据来帮助定义健康或最佳水平。尽管考虑到血清维生素D水平低于25nmol/l是维生素D状态的最低临界值,但有证据表明,血清维生素D浓度高于25nmol/l的婴幼儿也可能发生佝偻病。该研究旨在确定在看似健康的尼日利亚医院工作人员和患者护理人员中维生素D缺乏症的患病率和危险因素,并可能为临床补充维生素D提供依据。这是一项描述性、横断面的多中心研究,在2019年1月至2019年3月期间,对来自该国三个地缘政治区域的198名参与者进行了研究。采用多阶段抽样方法选择该国的地缘政治区域和三级医院,而采用简单随机抽样方法从每个区域选择参与者。采用Calbiotech Inc .试剂盒检测血清维生素D水平。超过68%的参与者血清维生素D水平充足,而30.8%的参与者血清维生素D水平较低,后者构成了本研究中维生素D缺乏症的患病率。只有一名参与者血清中维生素D含量超标。这项研究表明,大约三分之一的样本人群患有维生素D缺乏症。这表明黑人需要对维生素D进行常规评估和补充。
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引用次数: 0
The effect of Health Education on the knowledge, attitude and uptake of Malaria Preventive Practices among Caregivers of Under-Fives in Nigeria : a systematic review 健康教育对尼日利亚五岁以下儿童护理人员疟疾预防措施的知识、态度和吸收的影响:一项系统审查
Pub Date : 2023-04-25 DOI: 10.4314/tjhc.v30i1.3
N. Usman, B. Grace, B. Nwankwo, R. Zubairu, M. Ogunsina
The elimination of malaria by 2030 is one of the targets of the Sustainable Development Goals. However, malaria remains a public health issue causing morbidity and mortality especially among under-fives in sub-Saharan African countries like Nigeria. Suboptimal health knowledge and poor preventive practices for malaria are prevalent in Nigeria. This study determined the effect of health education on the knowledge, attitude, and uptake of malaria preventive practices among caregivers of under-fives in Nigeria. The Cochrane Library guidelines and the PRISMA checklist were used to conduct a systematic review. PubMed, ProQuest, CINAHL and Cochrane Library were the electronic databases used to search for literature published between 2000 and 2022. The initial search yielded 475 studies but only eight of them met the inclusion criteria. At baseline only 3% to 48.4% of the respondents in the experimental group had good knowledge of malaria prevention. This proportion increased after the intervention with findings ranging from 55.8% to 88.7%. The proportion of respondents in the experimental group with good attitude towards malaria prevention increased from 60.5% at baseline to 97.4% after the intervention. Only 16% to 40% of the respondents in the experimental group had good preventive practices against malaria at baseline. After the intervention, the proportion increased (72.6% to 100%). The changes observed in the study (experimental) group were statistically significant i.e., p<0.05. The findings in the control groups were comparable to the study group at baseline however there was no statistically significant increase at the end of the study. Health education has been found to improve knowledge, attitude towards and preventive practices for malaria. In order to achieve effective control of malaria a comprehensive approach needs to be instituted. 
到2030年消除疟疾是可持续发展目标的具体目标之一。然而,疟疾仍然是一个公共卫生问题,造成发病率和死亡率,特别是在尼日利亚等撒哈拉以南非洲国家的五岁以下儿童中。尼日利亚普遍存在不理想的卫生知识和不良的疟疾预防做法。本研究确定了健康教育对尼日利亚五岁以下儿童护理人员的知识、态度和疟疾预防措施的影响。采用Cochrane图书馆指南和PRISMA检查表进行系统评价。PubMed、ProQuest、CINAHL和Cochrane图书馆是用于检索2000年至2022年间发表的文献的电子数据库。最初的搜索产生了475项研究,但其中只有8项符合纳入标准。在基线时,实验组中只有3%至48.4%的应答者对疟疾预防有良好的了解。这一比例在干预后增加,结果从55.8%到88.7%不等。实验组对疟疾预防态度良好的受访者比例由基线时的60.5%提高到干预后的97.4%。实验组中只有16%至40%的答复者在基线时采取了良好的疟疾预防措施。干预后,该比例由72.6%上升至100%。研究(实验)组差异有统计学意义,p<0.05。对照组的研究结果在基线时与研究组相当,但在研究结束时没有统计学上的显著增加。健康教育有助于提高对疟疾的认识、态度和预防措施。为了实现对疟疾的有效控制,需要制定一项综合办法。
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Tropical Journal of Health Sciences
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