Florin Marcu, D. Ciobanu, I. Boca, Elena Sirbu, Paul Alexandru Deme, Nicolae Cătălin Hreniuc, D. Ianc
{"title":"Rehabilitation therapy versus drug-only therapy in patients with multiple sclerosis","authors":"Florin Marcu, D. Ciobanu, I. Boca, Elena Sirbu, Paul Alexandru Deme, Nicolae Cătălin Hreniuc, D. Ianc","doi":"10.55730/1300-0144.5776","DOIUrl":"https://doi.org/10.55730/1300-0144.5776","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140520064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Damadoğlu, Özge Öztürk Aktaş, B. Gemicioğlu, Nafiye Yilmaz, Fulsen Bozkuş, Vehbi Ayhan, A. F. Kalpaklioglu, F. Erkekol, Y. Havlucu, F. Erel, Ömür Aydin, A. Ekici, A. Baccioglu, S. Barış, G. Buhari, Berrin Ceyhan, Ö. Göksel, Mehmet Köse, A. B. Dursun, F. Yıldız, A. Yorgancioglu, S. R. Işık, D. Ediger, İ. K. Oğuzülgen, A. U. Demir, G. Karakaya, A. Kalyoncu
{"title":"Elderly and aged asthma have different characteristics: results of a multicenter study","authors":"E. Damadoğlu, Özge Öztürk Aktaş, B. Gemicioğlu, Nafiye Yilmaz, Fulsen Bozkuş, Vehbi Ayhan, A. F. Kalpaklioglu, F. Erkekol, Y. Havlucu, F. Erel, Ömür Aydin, A. Ekici, A. Baccioglu, S. Barış, G. Buhari, Berrin Ceyhan, Ö. Göksel, Mehmet Köse, A. B. Dursun, F. Yıldız, A. Yorgancioglu, S. R. Işık, D. Ediger, İ. K. Oğuzülgen, A. U. Demir, G. Karakaya, A. Kalyoncu","doi":"10.55730/1300-0144.5792","DOIUrl":"https://doi.org/10.55730/1300-0144.5792","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140520942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between trunk control, spinal posture, and spinal mobility in patients with multiple sclerosis: a cross-sectional study","authors":"Taşkın Özkan, Nezehat Özgül Ünlüer, Mustafa Ertuğrul Yaşa, Buse Korkmaz, Gönül Vural","doi":"10.55730/1300-0144.5778","DOIUrl":"https://doi.org/10.55730/1300-0144.5778","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140522398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Köstek, Uygar Demi̇r, Ramazan Uçak, Burak Yasin Avci, Aydın Ünal, O. B. Gülçiçek, Ozan Caliskan, B. Citgez, Erdinc Serin, S. Yetkin, M. Mihmanlı, M. Uludağ
formation is a technique defined for the treatment of short
形成是为治疗短路而定义的一种技术。
{"title":"Effects of glutamine and omega-3 fatty acids on intestinal neomucosa formation on colon serosa in rats","authors":"Mehmet Köstek, Uygar Demi̇r, Ramazan Uçak, Burak Yasin Avci, Aydın Ünal, O. B. Gülçiçek, Ozan Caliskan, B. Citgez, Erdinc Serin, S. Yetkin, M. Mihmanlı, M. Uludağ","doi":"10.55730/1300-0144.5766","DOIUrl":"https://doi.org/10.55730/1300-0144.5766","url":null,"abstract":"formation is a technique defined for the treatment of short","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140516256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Altuntaş, Medine Nur Özata Değerli, Ege Temizkan, Gamze Eki̇ci̇
{"title":"Psychometric properties of t e Canadian occupational performance measure in older individuals","authors":"O. Altuntaş, Medine Nur Özata Değerli, Ege Temizkan, Gamze Eki̇ci̇","doi":"10.55730/1300-0144.5796","DOIUrl":"https://doi.org/10.55730/1300-0144.5796","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140519537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/aim: This study aims to determine the possible embryotoxic effects of propofol on the cerebellum and spinal cord using fertile chicken eggs. Materials and methods: A total of 430 fertile eggs were divided into 5 groups: control, saline, 2.5 mg.kg –1 , 12.5 mg.kg –1 , and 37.5 mg.kg –1 propofol. Injections were made immediately before incubation via the air chamber. On the 15th, 18th, and 21st day of incubation, 6 embryos from each group were evaluated. Serial paraffin sections taken from the cerebellum and spinal cord were stained with hematoxylin–eosin, Kluver–Barrera, toluidine blue, and periodic acid-Schiff’s reaction. The outer granular layer and total cortex thickness were measured, and the linear density of the Purkinje cells was determined. The ratios of the substantia grisea surface area to the total surface area of the spinal cord were calculated. The transverse and longitudinal diameters of the canalis centralis were also assessed. Results: No structural malformation was observed in any embryos examined macroscopically. No significant difference was observed between the groups in terms of development and histologic organization of the cerebellum and spinal cord. However, on the 15th, 18th, and 21st day, the outer granular layer (p < 0.001 for all days) and the total cortex thickness (p < 0.01, p < 0.001, and p < 0.001, respectively) decreased significantly in different propofol dose groups in varying degrees in the cerebellum. Similarly, in the spinal cord, there were significant changes in the ratios of the substantia grisea surface area to the total surface area (p < 0.01 and p < 0.001, respectively). Conclusion: It was concluded that the in-ovo-administered propofol given immediately before incubation has adverse effects on the developing cerebellum and spinal cord. Therefore, it is important for anesthesiologists always to remain vigilant when treating female patients of childbearing age.
背景/目的：本研究旨在利用能育鸡卵确定异丙酚对小脑和脊髓可能产生的胚胎毒性影响。材料和方法：将 430 枚受精蛋分为 5 组：对照组、生理盐水组、2.5 mg.kg -1 组、12.5 mg.kg -1 组和 37.5 mg.kg -1 组。孵化前立即通过气室注射。在孵化的第 15、18 和 21 天，对每组的 6 个胚胎进行评估。小脑和脊髓的石蜡切片经苏木精-伊红、克鲁弗-巴雷拉、甲苯胺蓝和周期性酸-希夫反应染色。测量了外颗粒层和皮层总厚度，并测定了浦肯野细胞的线性密度。计算了灰质表面积与脊髓总表面积的比率。此外，还评估了中央突的横向和纵向直径。结果经宏观检查，所有胚胎均未发现结构畸形。在小脑和脊髓的发育和组织学组织方面，各组之间未发现明显差异。然而，在第 15、18 和 21 天，不同异丙酚剂量组的小脑外颗粒层（所有天数的 p < 0.001）和皮层总厚度（分别为 p < 0.01、p < 0.001 和 p < 0.001）均有不同程度的显著下降。同样，在脊髓中，灰质表面积与总表面积的比率也有显著变化（分别为 p < 0.01 和 p < 0.001）。结论结论：在孵化前立即静脉注射异丙酚会对发育中的小脑和脊髓产生不良影响。因此，麻醉医生在治疗育龄期女性患者时必须时刻保持警惕。
{"title":"Determination of the embryotoxic effects of propofol injected into eggs on the cerebellum and spinal cord using histologic methods: an animal study","authors":"Murat İzgi̇, Emrah Sur","doi":"10.55730/1300-0144.5760","DOIUrl":"https://doi.org/10.55730/1300-0144.5760","url":null,"abstract":"Background/aim: This study aims to determine the possible embryotoxic effects of propofol on the cerebellum and spinal cord using fertile chicken eggs. Materials and methods: A total of 430 fertile eggs were divided into 5 groups: control, saline, 2.5 mg.kg –1 , 12.5 mg.kg –1 , and 37.5 mg.kg –1 propofol. Injections were made immediately before incubation via the air chamber. On the 15th, 18th, and 21st day of incubation, 6 embryos from each group were evaluated. Serial paraffin sections taken from the cerebellum and spinal cord were stained with hematoxylin–eosin, Kluver–Barrera, toluidine blue, and periodic acid-Schiff’s reaction. The outer granular layer and total cortex thickness were measured, and the linear density of the Purkinje cells was determined. The ratios of the substantia grisea surface area to the total surface area of the spinal cord were calculated. The transverse and longitudinal diameters of the canalis centralis were also assessed. Results: No structural malformation was observed in any embryos examined macroscopically. No significant difference was observed between the groups in terms of development and histologic organization of the cerebellum and spinal cord. However, on the 15th, 18th, and 21st day, the outer granular layer (p < 0.001 for all days) and the total cortex thickness (p < 0.01, p < 0.001, and p < 0.001, respectively) decreased significantly in different propofol dose groups in varying degrees in the cerebellum. Similarly, in the spinal cord, there were significant changes in the ratios of the substantia grisea surface area to the total surface area (p < 0.01 and p < 0.001, respectively). Conclusion: It was concluded that the in-ovo-administered propofol given immediately before incubation has adverse effects on the developing cerebellum and spinal cord. Therefore, it is important for anesthesiologists always to remain vigilant when treating female patients of childbearing age.","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140526301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The right ventricle outflow tract systolic function could predict the severity of the cirrhosis","authors":"İbrahim Dönmez, Güray Can, Emrah Acar","doi":"10.55730/1300-0144.5785","DOIUrl":"https://doi.org/10.55730/1300-0144.5785","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Ak, Zeynep Tuz, Esra Aydın, F. Ferhatoğlu, Murat Sari, N. Paksoy, I. Dogan, Anıl Yildiz, Rian Di̇şçi̇, P. Saip
{"title":"The effect of parity, breastfeeding history, and duration on clinical and pathological characteristics of breast cancer patients","authors":"N. Ak, Zeynep Tuz, Esra Aydın, F. Ferhatoğlu, Murat Sari, N. Paksoy, I. Dogan, Anıl Yildiz, Rian Di̇şçi̇, P. Saip","doi":"10.55730/1300-0144.5784","DOIUrl":"https://doi.org/10.55730/1300-0144.5784","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140517711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ö. Karaahmet, E. Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Z. Bahtiyarca, E. Umay
{"title":"Evaluation of bone health in terms of osteoporosis in adult patients with neuromuscular disease","authors":"Ö. Karaahmet, E. Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Z. Bahtiyarca, E. Umay","doi":"10.55730/1300-0144.5794","DOIUrl":"https://doi.org/10.55730/1300-0144.5794","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140519050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The otential mechanism of treating IC/BPS with hyperbaric oxygen by reducing vascular endothelial growth inhibitor and hypoxia-inducible factor-1α","authors":"Jing Zhang, Jiarui Kang, Liyang Wu","doi":"10.55730/1300-0144.5762","DOIUrl":"https://doi.org/10.55730/1300-0144.5762","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140524398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：