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Urolithiasis最新文献

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Association between calcium-Sensing receptor gene polymorphisms and urinary calcium stone formation in the Han Chinese population from a High-Altitude region (Kunming) in China. 中国高海拔地区（昆明）汉族人群钙敏感受体基因多态性与尿钙结石形成的关系
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2026-01-03 DOI: 10.1007/s00240-025-01928-5
Junkun Hou, Pan Liu, Sida Wang, Benhong Li, Jiawei Guan, Junfeng Yang

This case-control study investigated the association between calcium-sensing receptor (CaSR) gene polymorphisms and calcium-containing kidney stone susceptibility in 100 patients and 100 matched healthy controls from the Kunming Han Chinese population. Genotyping of three CaSR loci (rs1042636, rs1801725, and rs1801726) was performed using SNaPshot technology. The rs1801725 GT genotype significantly increased stone formation risk (odds ratio = 1.50, 95% confidence interval: 1.10-2.00, P = 0.042) and was associated with elevated 24-hour urinary calcium excretion compared with controls (10.683 ± 2.535 vs. 7.436 ± 1.742 mmol/24 h, P = 0.002), suggesting impaired renal tubular calcium reabsorption as the underlying mechanism. No significant association was found for rs1042636, while rs1801726 exhibited complete monomorphism (100% CC genotype) across all samples. This study provides the first evidence that the CaSR rs1801725 GT genotype serves as an independent genetic risk marker for urinary calcium stones in the Kunming Han Chinese population. Future research should integrate additional calcium transport pathway genes to develop polygenic risk prediction models and elucidate gene-environment interactions in stone pathogenesis.

本病例对照研究调查了来自昆明汉族人群的100例患者和100例匹配的健康对照者的钙敏感受体（CaSR）基因多态性与含钙肾结石易感性之间的关系。采用SNaPshot技术对三个CaSR位点（rs1042636、rs1801725和rs1801726）进行基因分型。rs1801725 GT基因型显著增加结石形成风险（优势比= 1.50,95%可信区间：1.10-2.00,P = 0.042），与对照组相比，24小时尿钙排泄量升高（10.683±2.535 vs. 7.436±1.742 mmol/24 h, P = 0.002），提示肾小管钙重吸收障碍是其潜在机制。rs1042636未发现显著相关性，而rs1801726在所有样本中表现为完全单态（100% CC基因型）。本研究首次证明CaSR rs1801725 GT基因型是昆明汉族人群尿钙结石的独立遗传风险标记。未来的研究应整合更多的钙转运途径基因，以建立多基因风险预测模型，并阐明结石发病机制中基因与环境的相互作用。
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引用次数: 0
Learning curves after position switch in PCNL: prone- vs. supine-trained surgeons. PCNL患者体位转换后的学习曲线：俯卧与仰卧训练的外科医生。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2026-01-02 DOI: 10.1007/s00240-025-01924-9
Mucahit Gelmis, Ali Ayten, Oguzhan Yildiz, Hakan Ceylan, Kanan Maharramov, Enver Ozdemir
{"title":"Learning curves after position switch in PCNL: prone- vs. supine-trained surgeons.","authors":"Mucahit Gelmis, Ali Ayten, Oguzhan Yildiz, Hakan Ceylan, Kanan Maharramov, Enver Ozdemir","doi":"10.1007/s00240-025-01924-9","DOIUrl":"https://doi.org/10.1007/s00240-025-01924-9","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"24"},"PeriodicalIF":2.2,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salidroside attenuates calcium oxalate-induced renal injury via suppression of PANoptosis. 红景天苷通过抑制PANoptosis减轻草酸钙诱导的肾损伤。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2026-01-02 DOI: 10.1007/s00240-025-01927-6
Guoxiang Li, Zhenyu Song, Junfeng Yao, Yang Chen, Yuexian Xu, Zongyao Hao
{"title":"Salidroside attenuates calcium oxalate-induced renal injury via suppression of PANoptosis.","authors":"Guoxiang Li, Zhenyu Song, Junfeng Yao, Yang Chen, Yuexian Xu, Zongyao Hao","doi":"10.1007/s00240-025-01927-6","DOIUrl":"https://doi.org/10.1007/s00240-025-01927-6","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"25"},"PeriodicalIF":2.2,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of super-pulse thulium fiber laser compared to holmium: YAG laser for ureteral and renal stones: a multicenter retrospective study. 超脉冲铥光纤激光与钬激光治疗输尿管结石和肾结石的疗效和安全性：一项多中心回顾性研究。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2025-12-29 DOI: 10.1007/s00240-025-01915-w
Muhammad Usman, Zhouhang Li, Qingyou Zheng, Yang Cui, Changlong Cai, Wang He, Kewei Xu
{"title":"Efficacy and safety of super-pulse thulium fiber laser compared to holmium: YAG laser for ureteral and renal stones: a multicenter retrospective study.","authors":"Muhammad Usman, Zhouhang Li, Qingyou Zheng, Yang Cui, Changlong Cai, Wang He, Kewei Xu","doi":"10.1007/s00240-025-01915-w","DOIUrl":"10.1007/s00240-025-01915-w","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"23"},"PeriodicalIF":2.2,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12748295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145850821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: The association between frailty index and all-cause mortality in US individuals with kidney stones. 致编辑信：美国肾结石患者虚弱指数与全因死亡率之间的关系。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2025-12-29 DOI: 10.1007/s00240-025-01926-7
İbrahim Altundağ
{"title":"Letter to the editor: The association between frailty index and all-cause mortality in US individuals with kidney stones.","authors":"İbrahim Altundağ","doi":"10.1007/s00240-025-01926-7","DOIUrl":"https://doi.org/10.1007/s00240-025-01926-7","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"22"},"PeriodicalIF":2.2,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145850816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recognizing uric acid type of urinary stones by deep learning. 通过深度学习识别尿酸型尿路结石。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2025-12-26 DOI: 10.1007/s00240-025-01922-x
Bin Wang, Yingying Zhou, Jiaxin Cai
{"title":"Recognizing uric acid type of urinary stones by deep learning.","authors":"Bin Wang, Yingying Zhou, Jiaxin Cai","doi":"10.1007/s00240-025-01922-x","DOIUrl":"https://doi.org/10.1007/s00240-025-01922-x","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"21"},"PeriodicalIF":2.2,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GGT1 protects against calcium oxalate crystal-induced renal tubular epithelial cell injury by targeting GCLC. GGT1通过靶向GCLC保护草酸钙晶体诱导的肾小管上皮细胞损伤。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2025-12-24 DOI: 10.1007/s00240-025-01923-w
Junfeng Yao, Guoxiang Li, Yuexian Xu, Yang Chen, Xudong Shen, Zongyao Hao
{"title":"GGT1 protects against calcium oxalate crystal-induced renal tubular epithelial cell injury by targeting GCLC.","authors":"Junfeng Yao, Guoxiang Li, Yuexian Xu, Yang Chen, Xudong Shen, Zongyao Hao","doi":"10.1007/s00240-025-01923-w","DOIUrl":"https://doi.org/10.1007/s00240-025-01923-w","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"20"},"PeriodicalIF":2.2,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145820735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When should we stop operating? Multicenter analysis of operative time, outcomes, and complications in ureteroscopy with flexible navigable suction access sheath (FANS) by EAU Endourology. 我们应该什么时候停止运营？EAU Endourology输尿管镜下柔性可导航吸入鞘（FANS）手术时间、结果及并发症的多中心分析。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2025-12-23 DOI: 10.1007/s00240-025-01913-y
Mohammed Zain Ulabedin Adhoni, Vineet Gauhar, Oliver Traxer, Thomas Herrmann, Daniele Castellani, Steffi Kar Kei Yuen, Bhaskar Somani
{"title":"When should we stop operating? Multicenter analysis of operative time, outcomes, and complications in ureteroscopy with flexible navigable suction access sheath (FANS) by EAU Endourology.","authors":"Mohammed Zain Ulabedin Adhoni, Vineet Gauhar, Oliver Traxer, Thomas Herrmann, Daniele Castellani, Steffi Kar Kei Yuen, Bhaskar Somani","doi":"10.1007/s00240-025-01913-y","DOIUrl":"https://doi.org/10.1007/s00240-025-01913-y","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"19"},"PeriodicalIF":2.2,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary inflammatory index and phenotypic age mediate the association between the dietary index for gut microbiota and kidney stone disease among U.S. overweight/obese adults. 饮食炎症指数和表型年龄介导了美国超重/肥胖成人肠道微生物群饮食指数与肾结石疾病之间的关系。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2025-12-23 DOI: 10.1007/s00240-025-01921-y
Wanting Gao, Nan Luo, Yusen Ou, Junjie Lu, Chao Tian, Suquan Zhong
{"title":"Dietary inflammatory index and phenotypic age mediate the association between the dietary index for gut microbiota and kidney stone disease among U.S. overweight/obese adults.","authors":"Wanting Gao, Nan Luo, Yusen Ou, Junjie Lu, Chao Tian, Suquan Zhong","doi":"10.1007/s00240-025-01921-y","DOIUrl":"https://doi.org/10.1007/s00240-025-01921-y","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"18"},"PeriodicalIF":2.2,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of risk factors for urinary tract infections caused by extended spectrum β-Lactamases-producing Escherichia coli and establish the nomogram model. 广谱产β-内酰胺酶大肠杆菌引起尿路感染的危险因素分析并建立nomogram模型。
IF 2.2 2区 医学 Q2 UROLOGY & NEPHROLOGY
Urolithiasis
Pub Date : 2025-12-22 DOI: 10.1007/s00240-025-01798-x
Qiang Feng, Wenqiong He, Qian Xu, Weineng Cheng
{"title":"Analysis of risk factors for urinary tract infections caused by extended spectrum β-Lactamases-producing Escherichia coli and establish the nomogram model.","authors":"Qiang Feng, Wenqiong He, Qian Xu, Weineng Cheng","doi":"10.1007/s00240-025-01798-x","DOIUrl":"https://doi.org/10.1007/s00240-025-01798-x","url":null,"abstract":"","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"54 1","pages":"7"},"PeriodicalIF":2.2,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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