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UMJ Heart & Vessels最新文献

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Experience in treatment of post-traumatic arteriovenous discharges syndrome resulting from gunshot wounds of the main vessels 主血管枪伤所致创伤后动静脉放电综合征的治疗体会
Pub Date : 2018-09-20 DOI: 10.30978/HV2018-3-84
V. Rogovskiy, B. Koval, O. Rodionov, I. I. Avgustinovych, A. A. Pysarenko
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引用次数: 0
Prediction of functional consequences of cerebral ischemic stroke one year after its occurrence 缺血性脑卒中发生一年后功能后果的预测
Pub Date : 2018-09-20 DOI: 10.30978/HV2018-3-28
T. Cherenko, Yu.L. Heletyuk
The aim —  investigation of independent prognostic factors of minimal dependence in everyday activities one year after ischemic stroke by developing a prognostic mathematical model. Materials and methods. The neurological and functional status of 150 patients (74 (49.3 %) women and 76 (50.7 %) men of mean age of (67.4 ± 0.7 years) with primary ischemic stroke and primary arterial hypertension in anamnesis was evaluated. Neurological deficit was evaluated by the NIHSS scale. The assessment of everyday life activity was provided by Bartel index (BI). The cognitive status was evaluated by MMSE scale. Diagnosis of hypertension was based on the results of clinical, instrumental examination and medical documentation. We applied daily blood pressure (BP) monitoring from the moment of admission every 4 hours for 6 days of acute period. The variability of SBP and DBP was determined by calculating the standard deviation for 6 days, as well as for the period from the first to the third and from the third to the sixth day. Results and discussion. A year after stroke, the median of the Barthel index values was 85, the minimum value was 45, the maximum — 100, the first quartile — 75, the third quartile — 95 points. Data on 105 patients with neurological deficit of moderate (82) and severe (23) degrees took part in the determination of the functional recovery prognostic predictors by BI. Of the 161 indicators that characterized the pathology and the results of an additional patient’s examination, 18 variables that had a reliable correlation with the BI score in a year were selected and involved in logistic regression analysis. According to the step­by­step analysis, (10 steps), the independent prognostic factors of minimal dependence in daily activities in a year were determined in patients with moderate and severe ischemic stroke: duration of hypertension (B coefficient = –0.11), thickness of the intima­media complex (B coefficient = –7.62), the MMSE score (B coefficient = 0.19), gender (B coefficient = –2.13), intake of sartans in combination with calcium antagonists or in monotherapy (B coefficient = –1.31), achievement of target BP in antihypertension therapy (its efficiency) (B coefficient = +2.95); constant — 7.43. The obtained model has a sensitivity of 95.3 %, a specificity of 88.9 % and a diagnostic accuracy of 93.4 %, an area under the ROC curve — 0.926 (95 % confidence interval: 0.881 — 0.972). Conclusions. The main tasks at the stage of rehabilitation of patients for achievement of a minimum functional dependence in a year in the case of moderate to severe ischemic stroke is to prevent the progression of the atherosclerotic process, improve cognitive functions and achieve the primary hypertension treatment effectiveness.
目的:通过建立预后数学模型,研究缺血性脑卒中一年后日常活动依赖性最小的独立预后因素。材料和方法。对150例(女性74例(49.3%),男性76例(50.7%),平均年龄(67.4±0.7岁)的原发性缺血性脑卒中合并原发性动脉高血压患者的神经功能状况进行评价。神经功能缺损采用NIHSS量表评估。日常生活活动评价采用Bartel指数(BI)。采用MMSE量表评估认知状态。高血压的诊断是基于临床,仪器检查和医疗文件的结果。急性期6天,从入院时起每4小时进行每日血压监测。通过计算第6天、第1天至第3天、第3天至第6天的标准差来确定收缩压和舒张压的变异性。结果和讨论。中风后一年,Barthel指数的中位数为85,最小值为45,最大值为- 100,前四分位为- 75,第三四分位为- 95。105例中度(82)和重度(23)神经功能缺损患者的数据参与了BI功能恢复预后预测指标的确定。在表征病理和额外患者检查结果的161个指标中,选择了18个与一年内BI评分有可靠相关性的变量并参与逻辑回归分析。根据分步分析(10步),确定中重度缺血性脑卒中患者一年内日常活动依赖度最小的独立预后因素:高血压持续时间(B系数= -0.11)、内膜-中膜复合体厚度(B系数= -7.62)、MMSE评分(B系数= 0.19)、性别(B系数= -2.13)、沙坦类药物联合钙拮抗剂或单用沙坦类药物的摄入量(B系数= -1.31)、降压治疗达到目标血压(B系数= +2.95);常数- 7.43。该模型的灵敏度为95.3%,特异性为88.9%,诊断准确率为93.4%,ROC曲线下面积为0.926(95%置信区间为0.881 ~ 0.972)。结论。中重度缺血性脑卒中患者康复阶段的主要任务是防止动脉粥样硬化进程的进展,改善认知功能,达到原发性高血压的治疗效果,实现一年内最低程度的功能依赖。
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引用次数: 2
Markers of bone remodeling, 25(ОH)D3 level and lipid metabolism parameters in elderly women with uncomplicated arterial hypertension 老年女性无并发症动脉性高血压患者骨重塑指标、25(ОH)D3水平及脂质代谢参数
Pub Date : 2018-09-20 DOI: 10.30978/hv2018-3-60
O. I. Nishkumai, K. Lazarieva, G. Mostbauer, P. Lazariev, Yu. V. Rudenko
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引用次数: 0
Register of percutaneous coronary interventions: expanded comparative analysis of results of 2016  and 20 17. From reperfusion paradox to decrease of mortality 经皮冠状动脉介入登记:2016年和2017年结果的扩展对比分析。从再灌注悖论到死亡率的降低
Pub Date : 2018-09-20 DOI: 10.30978/hv2018-3-9
M. Sokolov
Ukrainian Association of Interventional Cardiology established Percutaneous Coronary Interventions Registry (PCI Registry) in 2010. The first protocol was filled on 12.04.2010. By now (23.07.2018, 17 h 58 min) the Registry was filled by 106,244 patients who underwent coronary angiography, percutaneous coronary intervention (PCI) or both procedures simultaneously. For the year 2017 in the clinics participating in the Registry, coronary angiography was performed on 32,112 patients (+9.3 %), PCI — on 14,510 patients (+12.6 %), PCI in STEMI patients — in 7,846 cases (+6 %). The number of PCI in patients with STEMI per million of population increased by 8.0 % compared to 2016 and amounted to 220 patients. The number of STEMI patients hospitalized for percutaneous reperfusion was quite adequate and corresponded to the main world trends in the treatment of acute myocardial infarction (0 — 4h — 44 %, 4 — 6h — 22 %, 6 — 12h — 20 %, 12 — 24h — only 14 %, respectively). The indicators of hospital mortality have noticeably changed in 11 regions of Ukraine (Vinnytsia, Dnipropetrovsk, Transcarpathian, Ivano-Frankivsk, Kyiv (together with the city of Kyiv), Lviv, Odesa, Poltava, Kharkiv, Kherson, Cherkasy), which have half of the population of the country and established regional reperfusion networks. The decrease of mortality due to acute myocardial infarction (АМІ) was statistically significant (p < 0.0001). The average hospital mortality in these regions was 11.6 % (14.2 % in the same regions in 2015), which is 18.3 % lower than in 2015. As a result of these changes in same areas in 2017, 420 lives more were saved than in 2015. The decrease in mortality in 11 regions caused a slight decrease in hospital mortality rate from AMI in the country: by 12.5 % in 2017, by 13.2 % in 2016. In some regions general indicators are still high. There was a tendency to increase the frequency of detection of patients with AMI without ST segment elevation: in 2016 — 424 per 1 million people, in 2017 — 489. Such an increase is fixed first during the existence of the Registry. It is possible that this phenomenon is caused by the consequences of the reperfusion paradox, which, in fact, were already pointed out during the development of the reperfusion system in European countries.
乌克兰介入心脏病学协会于2010年建立了经皮冠状动脉介入登记(PCI Registry)。第一份议定书于2010年4月12日填写。截至目前(2018年7月23日,17小时58分钟),登记的患者有106,244人同时接受了冠状动脉造影、经皮冠状动脉介入治疗(PCI)或两种手术。2017年,在参与登记的诊所中,对32,112例患者进行了冠状动脉造影(+ 9.3%),对14,510例患者进行了PCI(+ 12.6%),对STEMI患者进行了PCI - 7846例(+ 6%)。与2016年相比,每百万STEMI患者的PCI数量增加了8.0%,达到220例。STEMI患者经皮再灌注住院的人数相当充足,与世界急性心肌梗死治疗的主要趋势相符(0 - 4h - 44%, 4 - 6h - 22%, 6 - 12h - 20%, 12 - 24h -仅14%)。乌克兰11个地区(文尼察、第聂伯罗彼得罗夫斯克、外喀尔巴阡、伊万诺-弗朗科夫斯克、基辅(连同基辅市)、利沃夫、敖德萨、波尔塔瓦、哈尔科夫、赫尔松、切尔卡西)的医院死亡率指标发生了显著变化,这些地区的人口占全国人口的一半,并建立了区域再灌注网络。急性心肌梗死死亡率降低(АМІ),差异有统计学意义(p < 0.0001)。这些地区的平均住院死亡率为11.6%(2015年为14.2%),比2015年下降18.3%。由于这些变化,2017年在同一地区挽救的生命比2015年多420人。11个地区的死亡率下降导致该国急性心肌梗死的住院死亡率略有下降:2017年下降12.5%,2016年下降13.2%。在一些区域,总体指标仍然很高。无ST段抬高的AMI患者的检测频率有增加的趋势:2016年为每100万人424例,2017年为每100万人489例。这种增加首先在书记官处存在期间确定。这种现象可能是由再灌注悖论的后果造成的,事实上,欧洲国家在再灌注系统的发展过程中就已经指出了这一点。
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引用次数: 1
Surgical treatment of hypertrophic cardiomyopathy: what’s new? 肥厚性心肌病的手术治疗:有什么新进展?
Pub Date : 2018-07-05 DOI: 10.30978/HV201827
V. Lazoryshynets, K. Rudenko, O. Krykunov, A. Rusnak, O. Trembovetska, L. Nevmerzhytska, P. Danchenko
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引用次数: 0
Prevention of cardiac events in perioperative period in patients with acute calculous cholecystitis and coronary heart disease 急性结石性胆囊炎合并冠心病围手术期心脏事件的预防
Pub Date : 2018-07-05 DOI: 10.30978/HV2018223
V. Mishalov, S. O. Kondratenko, L. Markulan
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引用次数: 0
Preoperative planning of on-pump beating-heart coronary artery bypass grafting based on prediction of intraoperative complications 基于术中并发症预测的无泵心脏搭桥术术前规划
Pub Date : 2018-07-05 DOI: 10.30978/hv2018246
O. Zhurba
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引用次数: 0
Influence of unrecovered bloodflow phenomenon in patients with acute myocardial infarction with ST segment elevation after percutaneous coronary intervention on the dynamics of some echocardiography indicators during long-term follow-up 急性心肌梗死ST段抬高患者经皮冠状动脉介入治疗后未恢复血流现象对长期随访中超声心动图部分指标动态的影响
Pub Date : 2018-07-05 DOI: 10.30978/hv2018260
V. Tseluyko, M. M. Dyolog, O. Leonenko
Мета роботи  — визначити вплив феномена невідновленого кровотоку (ФНК) після проведення черезшкірного коронарного втручання (ЧКВ) на динаміку змін кінцеводіастолічного індексу (КДІ), кінцевосистолічного індексу (КСІ) та фракції викиду (ФВ) лівого шлуночка (ЛШ) у пацієнтів з гострим інфарктом міокарда з елевацією сегмента ST (STEMI). Матеріали і методи. У дослідженні взяли участь 105 пацієнтів віком від 36 до 85 років (у середньому (60,4 ± 2,0) року), котрих госпіталізували до Харківської міської клінічної лікарні № 8 у період із січня 2014 р. до вересня 2017 р. з діагнозом STEMI та у середньому через (7,6 ± 1,2) години після виникнення перших ознак захворювання провели ЧКВ. ФНК визначали за допомогою індексу MBG (Myocardial Blush Grade) як відсутність оптимальної міокардіальної перфузії в разі індексу MBG ≤ 2 балів. Основну групу склали 12 (16,7 %) пацієнтів з ФНК, контрольну — 60 (83,3 %) пацієнтів, чиї ангіографічні дані відповідали критеріям успішної ЧКВ. За час спостереження 72 пацієнтам, залученим у дослідження, тричі було проведено ехокардіографію — у середньому через (1,1 ± 0,6), (9,3 ± 1,2) та (8,3 ± 0,6) міс з моменту інвазивного втручання. Критеріями несприятливого перебігу ремоделювання ЛШ вважали збільшення КДІ ЛШ більш ніж на 20 % через (8,3 ± 0,6) міс порівняно з початковим та збільшення КСІ ЛШ понад 35 мл/м2. Критерієм несприятливих змін ФВ через (8,3 ± 0,6) міс після STEMI слугувало значення цього показника ≤ 40 %. Результати та обговорення. Вихідні досліджувані ехокардіографічні характеристики у групах пацієнтів статистично значуще не відрізнялися. Пацієнти основної групи демонстрували статистично значущо гірші результати ремоделювання ЛШ за даними ехокардіографії порівняно з контрольною групою: збільшення КДІ понад 20 % від вихідного значення (відношення шансів (ВШ) 10,6; 95 % довірчий інтервал (ДІ) 2,63 — 42,65; р   5 % (ВШ 0,05; 95 % ДІ 0,06 — 0,41; р   0,05). Висновки. Розвиток ФНК у вигляді порушення міокардіальної перфузії після проведення ЧКВ у пацієнтів з STEMI асоціюється з розвитком несприятливого ремоделювання ЛШ через (8,3 ± 0,6) міс спостереження, а саме зі збільшенням КДІ та КСІ ЛШ, відсутністю позитивної динаміки ФВ ЛШ.
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引用次数: 0
To the issue of corrosion of occluders from beta-zirconium alloy in experimental study of endovascular devices for the closure of arterial duct 针对血管内动脉导管封闭装置实验研究中β -锆合金封堵器的腐蚀问题
Pub Date : 2018-07-05 DOI: 10.30978/hv2018238
Yuri Panichkin, V. Zakharova, Yu.L. Konopliova, A. Yu. Gavrilishin, E. V. Beshlyaga, Izabela Skiba, M. Pogorelov, A. Solodovnik
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引用次数: 0
Clinical and anatomical variants of varicose veins in the basin of small subcutaneous vein 皮下小静脉盆腔静脉曲张的临床和解剖学变异
Pub Date : 2018-07-05 DOI: 10.30978/hv2018268
A. Guch, O. V. Ligonenko, O. I. Nabolotny
The aim — to distinguish variants of the topography of the small subcutaneous vein (SSV) and its femoral branch (FB) according to the ultrasound scan, as well as to determine the pathways for the spread of venous reflux and to develop anatomical and hemodynamic classification of varicose veins (VV) types. Materials and methods. We analyzed the results of the study of SSV topography variants in 474 patients of the general population and ways of distribution of blood reflux in SSV basin in 126 patients with VV, who were diagnosed and treated at O. O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine within the period of 2003 — 2007. Results and discussion. 6 variants of topography of SSV and 5 variants of topography of its FB were singled out. The most common variant, which occurs in 47.0 % of patients, is the influx of SSV into the popliteal vein with an isolated trunk. In the total number of the examined patients, SSVs had hip extension in the form of FB in 40.9 % and had no fistula with popliteal vein in 17.9 % of cases. The study of ways of venous reflux spreading made it possible to distinguish the following types of FB in the SSV basin: 1) the trunk type — in 76.2 %; 2) the inflow type — in 17.5 %; 3) the perforation type — in 6.3 % of patients. Conclusions. The most common type that occurs in 76.2 % of patients is the formation of blood reflux at the level of sapheno­popliteal fistula and its spread along the SSV trunk. Of the total number of patients with VV, an «atypical» distribution of blood reflux was registered in 23.8 % of cases.
目的-根据超声扫描区分小皮下静脉(SSV)及其股支(FB)的地形变化,以及确定静脉反流扩散的途径,并建立静脉曲张(VV)类型的解剖学和血流动力学分类。材料和方法。我们分析了2003 - 2007年在乌克兰NAMS的O. O. Shalimov国家外科和移植研究所诊断和治疗的126例VV患者中,474例普通人群中SSV地形变异的研究结果和SSV盆地血液反流的分布方式。结果和讨论。筛选出SSV地形的6个变异和其FB地形的5个变异。最常见的变异,发生在47.0%的患者中,是SSV流入具有孤立干的腘静脉。在所有检查的患者中,40.9%的ssv有FB形式的髋关节伸展,17.9%的ssv没有腘静脉瘘。通过对静脉回流扩散方式的研究,可以区分出SSV盆内FB的以下类型:1)主干型-占76.2%;2)流入型-占17.5%;3)穿孔类型——6.3%的患者。结论。最常见的类型发生在76.2%的患者中,是在隐腘瘘水平形成血液反流并沿SSV干扩散。在VV患者的总人数中,23.8%的病例记录了“非典型”血液反流分布。
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引用次数: 0
期刊
UMJ Heart & Vessels
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