Pub Date : 2023-01-01DOI: 10.5336/anesthe.2022-91644
Onur PALABIYIK
Kafa travması nedeniyle oluşan travmatik beyin hasarı (TBH) yüksek morbidite ve mortalite ile seyreden ciddi bir sağlık sorunudur. TBH'de tedavi arayışları sürecinde nöroproteksiyon sağlamak amacıyla birçok farmakolojik ajan uygulanmıştır. Amantadin, N-metil D-aspartat reseptörlerine antagonist etkisi yanında dopaminerjik reseptörlere de direkt agonistik etkisiyle nöroproteksiyon sağlamaktadır. Yoğun bakım ünitesinde, Glasgow Koma Skoru (GKS) 10'un altında olan 16- 72 yaş arasındaki 5 kafa travmalı hastaya standart tedaviye ek olarak amantadin protokolü (ilk hafta 200 mg/gün intravenöz infüzyon şeklinde, 2. hafta 200 mg/gün enteral yoldan, 3 ve 4. haftalarda ise 400 mg/gün enteral yoldan) uygulandı. Amantadin tedavisi ile GKS ve Güncellenmiş Komadan Çıkma Skalası skorlarında artış, Sakatlık Derecelendirme Ölçeği skorunda azalma saptandı. Sonuç olarak, TBH gelişmiş hastalarda amantadinin klinik ve nörofonksiyonel olarak iyileşmeye katkı sağladığını düşünmekteyiz.
{"title":"Neurocognitive Recovery with Amantadine in Intensive Care Unit Patients with Head Trauma: Case Series","authors":"Onur PALABIYIK","doi":"10.5336/anesthe.2022-91644","DOIUrl":"https://doi.org/10.5336/anesthe.2022-91644","url":null,"abstract":"Kafa travması nedeniyle oluşan travmatik beyin hasarı (TBH) yüksek morbidite ve mortalite ile seyreden ciddi bir sağlık sorunudur. TBH'de tedavi arayışları sürecinde nöroproteksiyon sağlamak amacıyla birçok farmakolojik ajan uygulanmıştır. Amantadin, N-metil D-aspartat reseptörlerine antagonist etkisi yanında dopaminerjik reseptörlere de direkt agonistik etkisiyle nöroproteksiyon sağlamaktadır. Yoğun bakım ünitesinde, Glasgow Koma Skoru (GKS) 10'un altında olan 16- 72 yaş arasındaki 5 kafa travmalı hastaya standart tedaviye ek olarak amantadin protokolü (ilk hafta 200 mg/gün intravenöz infüzyon şeklinde, 2. hafta 200 mg/gün enteral yoldan, 3 ve 4. haftalarda ise 400 mg/gün enteral yoldan) uygulandı. Amantadin tedavisi ile GKS ve Güncellenmiş Komadan Çıkma Skalası skorlarında artış, Sakatlık Derecelendirme Ölçeği skorunda azalma saptandı. Sonuç olarak, TBH gelişmiş hastalarda amantadinin klinik ve nörofonksiyonel olarak iyileşmeye katkı sağladığını düşünmekteyiz.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"280 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135754531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2023-98454
Duygu AKYOL, Necmiye AY, Ali KAHVECİOĞLU, Funda GÜMÜŞ ÖZCAN
Objective: Placenta accreta spectrum (PAS) is a condition with a high risk of perioperative bleeding that can cause maternal morbidity and mortality. Fibrinogen is the first factor of which level decreases in case of perioperative bleeding, although it increases in the last trimester of pregnancy. In this retrospective study, we aimed to evaluate the effect of fibrinogen use on preoperative and postoperative outcomes in PAS patients with high bleeding risk. Material and Methods: In this study, the files of 171 patients who were operated on with the diagnosis of antenatal PAS were examined retrospectively. Patients were divided into two groups according to fibrinogen use. Demographic data of both groups, choice of anesthesia, surgical application, amount of fluid, blood and blood product used peroperatively, amount of bleeding and postoperative complications were evaluated. Results: A total of 146 patients were included in the study. Patients were divided into two groups: group without fibrinogen concentrate (GNF, n=93) and group with fibrinogen concentrate (GF, n=53). The amount of preoperative bleeding, blood utilization and the total amount of fluid given was higher in GF compared to GNF (p<0.05). Postoperative hospital and intensive care unit (ICU) hospitalization history was higher in GF (p<0.05). Conclusion: Fibrinogen concentrate can be used according to the amount of bleeding regardless of the preoperative fibrinogen value in case of bleeding in patients undergoing cesarean section with antenatal PAS. In these patients, anaesthesia management should be determined with a multidisciplinary approach by planning preoperative blood and blood products preparation and ICU according to bleeding and surgical method.
{"title":"Association of Fibrinogen Use in Cesarean Delivery with Bleeding and Blood Products in Patients with Plasenta Acreata Spectrum: A Retrospective Study","authors":"Duygu AKYOL, Necmiye AY, Ali KAHVECİOĞLU, Funda GÜMÜŞ ÖZCAN","doi":"10.5336/anesthe.2023-98454","DOIUrl":"https://doi.org/10.5336/anesthe.2023-98454","url":null,"abstract":"Objective: Placenta accreta spectrum (PAS) is a condition with a high risk of perioperative bleeding that can cause maternal morbidity and mortality. Fibrinogen is the first factor of which level decreases in case of perioperative bleeding, although it increases in the last trimester of pregnancy. In this retrospective study, we aimed to evaluate the effect of fibrinogen use on preoperative and postoperative outcomes in PAS patients with high bleeding risk. Material and Methods: In this study, the files of 171 patients who were operated on with the diagnosis of antenatal PAS were examined retrospectively. Patients were divided into two groups according to fibrinogen use. Demographic data of both groups, choice of anesthesia, surgical application, amount of fluid, blood and blood product used peroperatively, amount of bleeding and postoperative complications were evaluated. Results: A total of 146 patients were included in the study. Patients were divided into two groups: group without fibrinogen concentrate (GNF, n=93) and group with fibrinogen concentrate (GF, n=53). The amount of preoperative bleeding, blood utilization and the total amount of fluid given was higher in GF compared to GNF (p<0.05). Postoperative hospital and intensive care unit (ICU) hospitalization history was higher in GF (p<0.05). Conclusion: Fibrinogen concentrate can be used according to the amount of bleeding regardless of the preoperative fibrinogen value in case of bleeding in patients undergoing cesarean section with antenatal PAS. In these patients, anaesthesia management should be determined with a multidisciplinary approach by planning preoperative blood and blood products preparation and ICU according to bleeding and surgical method.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135754256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/anesthe.2021-85660
Aliye Okgün Alcan, Hakan Aygün, H. Avci
{"title":"Postoperative Hypothermia in Elderly Patients: A Prospective Study Examining Frequency and Risk Factors","authors":"Aliye Okgün Alcan, Hakan Aygün, H. Avci","doi":"10.5336/anesthe.2021-85660","DOIUrl":"https://doi.org/10.5336/anesthe.2021-85660","url":null,"abstract":"","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"643 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74732571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/anesthe.2022-90459
V. Baytaş, Dostali Aliyev, S. Karadag Erkoc, Sanem Çakar Turhan, F. Ökten
{"title":"The Effect of Patient Characteristics and Perioperative Conditions on Chronic Pain Developing After Lower Extremity Arthroplasty Interventions: A Retrospective Analysis of 3-Year Clinical Results","authors":"V. Baytaş, Dostali Aliyev, S. Karadag Erkoc, Sanem Çakar Turhan, F. Ökten","doi":"10.5336/anesthe.2022-90459","DOIUrl":"https://doi.org/10.5336/anesthe.2022-90459","url":null,"abstract":"","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"332 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80589182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/anesthe.2022-88989
Ş. Özgünay, Şermin Eminoğlu, Sinay Önen, Hande Gürbüz, Nermin Kılıçarslan, Derya Karasu, T. Onur
{"title":"Compassion and Chronic Fatigue in Anesthesiologists and Intensive Care Unit Workers in the COVID-19 Pandemic: A Descriptive Study","authors":"Ş. Özgünay, Şermin Eminoğlu, Sinay Önen, Hande Gürbüz, Nermin Kılıçarslan, Derya Karasu, T. Onur","doi":"10.5336/anesthe.2022-88989","DOIUrl":"https://doi.org/10.5336/anesthe.2022-88989","url":null,"abstract":"","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79566234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/anesthe.2021-86745
B. D. Kosovali, Gul Meral Kocabeyoglu, Ö. Soyal, N. M. Mutlu
{"title":"Features and Predictors of Mortality in Geriatric COVID-19 Patients in Intensive Care Unit: Retrospective Clinical Study","authors":"B. D. Kosovali, Gul Meral Kocabeyoglu, Ö. Soyal, N. M. Mutlu","doi":"10.5336/anesthe.2021-86745","DOIUrl":"https://doi.org/10.5336/anesthe.2021-86745","url":null,"abstract":"","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90554264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/anesthe.2022-89816
K. Arslan, Aykan Gülleroğlu
{"title":"Our Outpatient Anesthesia Management in a Pediatric Case with Cornelia de Lange Syndrome","authors":"K. Arslan, Aykan Gülleroğlu","doi":"10.5336/anesthe.2022-89816","DOIUrl":"https://doi.org/10.5336/anesthe.2022-89816","url":null,"abstract":"","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91291247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/anesthe.2021-87533
Meryem Gürel, Oğuz Lafcı, A. Gürel, H. Başar, Ayşe Özcan
{"title":"Gastric Emphysema Related to Percutan Endoscopic Gastrostomy","authors":"Meryem Gürel, Oğuz Lafcı, A. Gürel, H. Başar, Ayşe Özcan","doi":"10.5336/anesthe.2021-87533","DOIUrl":"https://doi.org/10.5336/anesthe.2021-87533","url":null,"abstract":"","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89986207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5336/anesthe.2022-87928
M. Bektaş, T. Çakan, Servi Yildirim, Yusuf Harun Iren, A. K. Yildiz, H. Başar, K. Ağras
{"title":"The Effect of Obturator Nerve Block on Surgical Success and Surgeons' Satisfaction in Transurethral Resection of Bladder Tumor: A Randomized Controlled Trial","authors":"M. Bektaş, T. Çakan, Servi Yildirim, Yusuf Harun Iren, A. K. Yildiz, H. Başar, K. Ağras","doi":"10.5336/anesthe.2022-87928","DOIUrl":"https://doi.org/10.5336/anesthe.2022-87928","url":null,"abstract":"","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"130 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86770299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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