Pub Date : 2023-01-01DOI: 10.5336/anesthe.2022-93743
Sevtap Hekimoglu Sahin, M. Şahin
environment can cause problems. Apart from environmental toxic exposures, stress and working indoors also play a role in increasing the risk for cardiotoxicity. In addition, spontaneous abortion, infertility, hematological diseases, liver diseases and psychomotor disorders in operating room workers and congenital malformations in their children may develop. In this review, our aim is to review cardiotoxicity that may develop due to exposure factors in operating room workers.
{"title":"Operating Room Employees and Cardiotoxicity: Traditional Review","authors":"Sevtap Hekimoglu Sahin, M. Şahin","doi":"10.5336/anesthe.2022-93743","DOIUrl":"https://doi.org/10.5336/anesthe.2022-93743","url":null,"abstract":"environment can cause problems. Apart from environmental toxic exposures, stress and working indoors also play a role in increasing the risk for cardiotoxicity. In addition, spontaneous abortion, infertility, hematological diseases, liver diseases and psychomotor disorders in operating room workers and congenital malformations in their children may develop. In this review, our aim is to review cardiotoxicity that may develop due to exposure factors in operating room workers.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91054734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: Koronavirüs hastalığı-2019 [coronavirus disease-2019 (COVID-19)] hastalarında, hastalığın ciddiyetini belirleme ve sonucu tahmin etmede yardımcı olarak sepsis ilişkili koagülopati, Ardışık Organ Yetmezliği Skoru ve Uluslararası Tromboz ve Hemostaz Derneği [International Society for Thrombosis and Hemostasis (ISTH)] yaygın damar içi pıhtılaşma [disseminated intravascular coagulation (DIC)] skoru gibi klinik skorlama sistemleri, kullanılabilmektedir. Bu çalışmada, yoğun bakım ünitesinde yatan COVID-19 hastalarında tromboembolik olay geçirme riskini belirlemek ve ISTH DIC skorlama sisteminin bu konudaki yararlılığını araştırmak amaçlanmıştır. Gereç ve Yöntemler: Anesteziyoloji kliniği 3. düzey COVID-19 yoğun bakımlarında 1 Temmuz 2020-1 Ocak 2022 tarihleri arasında yatan tüm hasta dosyaları retrospektif olarak incelendi. Hastaların demografik özellikleri, klinik ve laboratuvar bulguları, hastanede ve yoğun bakımda yatış süreleri ve sağkalımları kaydedildi. Hastalar tromboembolik olay gelişen (tromboz grubu) ve gelişmeyen hastalar (kontrol grubu) olmak üzere 2 gruba ayrıldı. Bulgular: Çalışmaya toplamda 1172 hasta dâhil edildi. Tromboembolik olay gelişen 136 hasta vardı. En sık görülen tromboembolik olay akut koroner sendromdu. Tromboz grubunda mortalite oranı daha yüksekti (p=0,012). ISTH DIC skoru hastaların büyük çoğunluğunda 2-5 puan arasındaydı ve gruplar arasında farklılık gözlenmedi (p=0,160). Sonuç: COVID-19 enfeksiyonu nedeniyle yoğun bakımda tedavi gören hastalarda tromboembolik olay görülme insidansı yüksektir ve mortalite üzerinde etkilidir. ISTH DIC skoru, yoğun bakım ihtiyacı olan COVID-19 hastalarında tromboembolik olay gelişimini öngörmede yeterli görünmemektedir.
{"title":"Frequency of Thromboembolic Events and Predictive Value of International Society for Thrombosis and Hemostasis Disseminated Intravascular Coagulation Score in COVID-19 Intensive Care Patients: Retrospective Analysis","authors":"Fatma ÖZKAN SİPAHİOĞLU, Eda MACİT AYDIN, Jülide ERGİL","doi":"10.5336/anesthe.2023-96270","DOIUrl":"https://doi.org/10.5336/anesthe.2023-96270","url":null,"abstract":"Amaç: Koronavirüs hastalığı-2019 [coronavirus disease-2019 (COVID-19)] hastalarında, hastalığın ciddiyetini belirleme ve sonucu tahmin etmede yardımcı olarak sepsis ilişkili koagülopati, Ardışık Organ Yetmezliği Skoru ve Uluslararası Tromboz ve Hemostaz Derneği [International Society for Thrombosis and Hemostasis (ISTH)] yaygın damar içi pıhtılaşma [disseminated intravascular coagulation (DIC)] skoru gibi klinik skorlama sistemleri, kullanılabilmektedir. Bu çalışmada, yoğun bakım ünitesinde yatan COVID-19 hastalarında tromboembolik olay geçirme riskini belirlemek ve ISTH DIC skorlama sisteminin bu konudaki yararlılığını araştırmak amaçlanmıştır. Gereç ve Yöntemler: Anesteziyoloji kliniği 3. düzey COVID-19 yoğun bakımlarında 1 Temmuz 2020-1 Ocak 2022 tarihleri arasında yatan tüm hasta dosyaları retrospektif olarak incelendi. Hastaların demografik özellikleri, klinik ve laboratuvar bulguları, hastanede ve yoğun bakımda yatış süreleri ve sağkalımları kaydedildi. Hastalar tromboembolik olay gelişen (tromboz grubu) ve gelişmeyen hastalar (kontrol grubu) olmak üzere 2 gruba ayrıldı. Bulgular: Çalışmaya toplamda 1172 hasta dâhil edildi. Tromboembolik olay gelişen 136 hasta vardı. En sık görülen tromboembolik olay akut koroner sendromdu. Tromboz grubunda mortalite oranı daha yüksekti (p=0,012). ISTH DIC skoru hastaların büyük çoğunluğunda 2-5 puan arasındaydı ve gruplar arasında farklılık gözlenmedi (p=0,160). Sonuç: COVID-19 enfeksiyonu nedeniyle yoğun bakımda tedavi gören hastalarda tromboembolik olay görülme insidansı yüksektir ve mortalite üzerinde etkilidir. ISTH DIC skoru, yoğun bakım ihtiyacı olan COVID-19 hastalarında tromboembolik olay gelişimini öngörmede yeterli görünmemektedir.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135754254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2022-90780
K. Arslan, Hale ÇETİN ARSLAN, Ayça SULTAN ŞAHİN
ABS TRACT Objective: During the coronavirus disease-2019 (COVID-19) pandemic, elective surgical operations were postponed, affecting emergency operations. This study aims to compare emergency surgical operations, anesthesia preferences, and patient outcomes in the early pandemic period with the pre-pandemic period and to investigate the effect of the pandemic on emergency operations. Material and Methods: Emergency surgical operations, surgical techniques, anesthesia preferences, and patient outcomes performed in the pandemic period between March 15-April 15, 2020, were compared with the emergency surgeries in the same period of 2019, which is the pre-pandemic period. Results: Demographic data were similar between groups. A 30% decrease was observed in the emergency surgeries performed in the pandemic group (n=236) compared to the pre-pandemic group (n=337). Although the cesarean section was the most common emergency surgery in both periods, a decrease was observed in emergency operations other than cesarean section during the pandemic. While trauma surgery, open surgical technique, spinal anesthesia preference, length of stay in the service, and mortality were high in the pandemic group, the length of stay in the intensive care unit was low. 7.2% of the patients (n=17) in the pandemic group were COVID-19 positive. Trauma surgery was not encountered in these patients, and all surgeries were performed with an open technique. Conclusion: In the early period of the COVID-19 pandemic, a decrease has been observed in the number of emergency surgical operations and emergency operations other than cesarean section, with the effect of medical treatment and follow-up. However, while more trauma surgery was performed during the pandemic, mortality was higher. While the laparoscopic technique decreased significantly, the preference for spinal anesthesia increased significantly.
{"title":"Evaluation of Emergency Operations and Anesthesia Preferences in the Early COVID-19 Pandemic and Before the Pandemic: A Retrospective Cross-Sectional Study","authors":"K. Arslan, Hale ÇETİN ARSLAN, Ayça SULTAN ŞAHİN","doi":"10.5336/anesthe.2022-90780","DOIUrl":"https://doi.org/10.5336/anesthe.2022-90780","url":null,"abstract":"ABS TRACT Objective: During the coronavirus disease-2019 (COVID-19) pandemic, elective surgical operations were postponed, affecting emergency operations. This study aims to compare emergency surgical operations, anesthesia preferences, and patient outcomes in the early pandemic period with the pre-pandemic period and to investigate the effect of the pandemic on emergency operations. Material and Methods: Emergency surgical operations, surgical techniques, anesthesia preferences, and patient outcomes performed in the pandemic period between March 15-April 15, 2020, were compared with the emergency surgeries in the same period of 2019, which is the pre-pandemic period. Results: Demographic data were similar between groups. A 30% decrease was observed in the emergency surgeries performed in the pandemic group (n=236) compared to the pre-pandemic group (n=337). Although the cesarean section was the most common emergency surgery in both periods, a decrease was observed in emergency operations other than cesarean section during the pandemic. While trauma surgery, open surgical technique, spinal anesthesia preference, length of stay in the service, and mortality were high in the pandemic group, the length of stay in the intensive care unit was low. 7.2% of the patients (n=17) in the pandemic group were COVID-19 positive. Trauma surgery was not encountered in these patients, and all surgeries were performed with an open technique. Conclusion: In the early period of the COVID-19 pandemic, a decrease has been observed in the number of emergency surgical operations and emergency operations other than cesarean section, with the effect of medical treatment and follow-up. However, while more trauma surgery was performed during the pandemic, mortality was higher. While the laparoscopic technique decreased significantly, the preference for spinal anesthesia increased significantly.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74072719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2023-98535
Meltem BEKTAŞ, Onur ERSAN
Amaç: Kas gevşetici etkilerinin geri döndürülmesinde rölatif olarak yeni bir ajan olan sugammadeks, hızlı etkisi ve rekürarizasyon oranlarındaki azalmayla güvenli kullanımda iyi bir alternatiftir. Bu çalışmada, sugammadeks kullanılan orta ve yaşlı gruptaki hastalarda uyanma ve derlenme hızıyla aynı dönemlerde gelişen yan etkilerin incelenmesi amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya, elektif cerrahide sugammadeks kullanılan, Amerikan Anestezistler Derneği 1-3, 50-64 yaş (Grup 1) ve 65-80 yaş (Grup 2) aralığında, 74 hasta dâhil edildi. Rutin anestezi indüksiyonuyla 0,6 mg/kg roküronyum uygulanan hastalarda dörtlü uyarı [train-of-four (TOF)]: 0 olduğunda endotrakeal entübasyon gerçekleştirildi. Her hasta için kullanılan kas gevşetici dozuna ve anestezistin kararına göre 2-4 mg/kg dozlarda sugammadeks uygulandı. Sugammadeks sonrası ve ekstübasyon sonrası TOF değerleri ve sugammadeks-ekstübasyon süresiyle ekstübasyon-derlenme odasına gidiş süreleri kaydedildi. Derlenme odasında 1, 5, 10 ve 15. dk'larda TOF değeri kaydedildi. Derlenme odasında komplikasyonlar (%92 altında satürasyon düşüklüğü, bradikardi, laringospazm) takip edildi. Bulgular: Grup 1'deki hastaların sugammadeks sonrası TOF değerleri, Grup 2'deki hastaların sugammadeks sonrası TOF değerlerinden anlamlı olarak fazla bulundu. Yine Grup 1'de sugammadeks verildikten sonra ekstübasyona kadar geçen süre anlamlı kısa bulunmuştur. Hastaların ekstübasyon sonrası derlenme odasına gönderilmesine kadar geçen süre Grup 1'de daha kısa bulunmuştur. Komplikasyon açısından sugammadeks sonrası gruplar arasında fark izlenmemiştir. Sonuç: Sonuç olarak, kas gevşetici etkisini geri döndürmede sadece sugammadeks kullanılan bu çalışmada, yaşlı hastalarda orta yaş grubuna göre sugammadeksin ekstübasyon ve derlenme odasına gönderme sürelerinin daha uzun olduğu, ancak iki grupta da belirgin komplikasyon bulunmadığı, bu etkilerin klinik yansımasının zayıf olduğu görülmüştür.
{"title":"Assessment of Recovery Characteristics and Side Effects in Middle-Aged and Geriatric Patients Receiving Sugammadex: Observational Study","authors":"Meltem BEKTAŞ, Onur ERSAN","doi":"10.5336/anesthe.2023-98535","DOIUrl":"https://doi.org/10.5336/anesthe.2023-98535","url":null,"abstract":"Amaç: Kas gevşetici etkilerinin geri döndürülmesinde rölatif olarak yeni bir ajan olan sugammadeks, hızlı etkisi ve rekürarizasyon oranlarındaki azalmayla güvenli kullanımda iyi bir alternatiftir. Bu çalışmada, sugammadeks kullanılan orta ve yaşlı gruptaki hastalarda uyanma ve derlenme hızıyla aynı dönemlerde gelişen yan etkilerin incelenmesi amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya, elektif cerrahide sugammadeks kullanılan, Amerikan Anestezistler Derneği 1-3, 50-64 yaş (Grup 1) ve 65-80 yaş (Grup 2) aralığında, 74 hasta dâhil edildi. Rutin anestezi indüksiyonuyla 0,6 mg/kg roküronyum uygulanan hastalarda dörtlü uyarı [train-of-four (TOF)]: 0 olduğunda endotrakeal entübasyon gerçekleştirildi. Her hasta için kullanılan kas gevşetici dozuna ve anestezistin kararına göre 2-4 mg/kg dozlarda sugammadeks uygulandı. Sugammadeks sonrası ve ekstübasyon sonrası TOF değerleri ve sugammadeks-ekstübasyon süresiyle ekstübasyon-derlenme odasına gidiş süreleri kaydedildi. Derlenme odasında 1, 5, 10 ve 15. dk'larda TOF değeri kaydedildi. Derlenme odasında komplikasyonlar (%92 altında satürasyon düşüklüğü, bradikardi, laringospazm) takip edildi. Bulgular: Grup 1'deki hastaların sugammadeks sonrası TOF değerleri, Grup 2'deki hastaların sugammadeks sonrası TOF değerlerinden anlamlı olarak fazla bulundu. Yine Grup 1'de sugammadeks verildikten sonra ekstübasyona kadar geçen süre anlamlı kısa bulunmuştur. Hastaların ekstübasyon sonrası derlenme odasına gönderilmesine kadar geçen süre Grup 1'de daha kısa bulunmuştur. Komplikasyon açısından sugammadeks sonrası gruplar arasında fark izlenmemiştir. Sonuç: Sonuç olarak, kas gevşetici etkisini geri döndürmede sadece sugammadeks kullanılan bu çalışmada, yaşlı hastalarda orta yaş grubuna göre sugammadeksin ekstübasyon ve derlenme odasına gönderme sürelerinin daha uzun olduğu, ancak iki grupta da belirgin komplikasyon bulunmadığı, bu etkilerin klinik yansımasının zayıf olduğu görülmüştür.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135754544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2022-94630
Ayşe Hande ARPACI, Berrin IŞIK
In the coronavirus disease-2019 (COVID-19) pandemic, which started in 2019 and was caused by the severe acute respiratory syndrome-coronavirus-2 virus, the clinical course of the infection was observed in a wide range from very mild symptoms to death. Although the respiratory system and lungs are mostly affected in COVID-19 infection, other organs and systems are also affected. The most common symptoms in COVID-19 are fever, cough, fatigue, difficulty breathing, anosmia, and loss of taste. In cases where clinical symptoms are more severe, acute respiratory distress syndrome, cytokine storms, multiple organ failure, sepsis and thrombosis are seen. Liver involvement has an important place in the course of COVID-19 apart from lung involvement, some patients with COVID-19 infection and cooperation difficulties require general anesthesia during computed tomography imaging procedures or intensive care treatments. Again, the need for urgent surgical intervention during infection causes them to be exposed to general anesthetics. The negative effects of general anesthesia agents on organ systems, especially on the liver, is an important issue that is frequently emphasized in the literature. Liver enzymes should be monitored in the clinical follow-up and estimation of mortality in patients with a diagnosis of COVID-19. Non-emergency surgeries of patients with a diagnosis of COVID-19 should be postponed or if anesthesia applications are necessary, non-hepatotoxic or minimally hepatotoxic methods should be performed. In this review, it is aimed to share information on anesthesia applications in terms of COVID-19 and liver functions by examining the relationship of COVID-19 with the liver.
{"title":"COVID-19, Anesthesia and Liver: Traditional Review","authors":"Ayşe Hande ARPACI, Berrin IŞIK","doi":"10.5336/anesthe.2022-94630","DOIUrl":"https://doi.org/10.5336/anesthe.2022-94630","url":null,"abstract":"In the coronavirus disease-2019 (COVID-19) pandemic, which started in 2019 and was caused by the severe acute respiratory syndrome-coronavirus-2 virus, the clinical course of the infection was observed in a wide range from very mild symptoms to death. Although the respiratory system and lungs are mostly affected in COVID-19 infection, other organs and systems are also affected. The most common symptoms in COVID-19 are fever, cough, fatigue, difficulty breathing, anosmia, and loss of taste. In cases where clinical symptoms are more severe, acute respiratory distress syndrome, cytokine storms, multiple organ failure, sepsis and thrombosis are seen. Liver involvement has an important place in the course of COVID-19 apart from lung involvement, some patients with COVID-19 infection and cooperation difficulties require general anesthesia during computed tomography imaging procedures or intensive care treatments. Again, the need for urgent surgical intervention during infection causes them to be exposed to general anesthetics. The negative effects of general anesthesia agents on organ systems, especially on the liver, is an important issue that is frequently emphasized in the literature. Liver enzymes should be monitored in the clinical follow-up and estimation of mortality in patients with a diagnosis of COVID-19. Non-emergency surgeries of patients with a diagnosis of COVID-19 should be postponed or if anesthesia applications are necessary, non-hepatotoxic or minimally hepatotoxic methods should be performed. In this review, it is aimed to share information on anesthesia applications in terms of COVID-19 and liver functions by examining the relationship of COVID-19 with the liver.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135754539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2022-94932
Z. Arslan, Huri Yeşildal, Enes Malik Akdas, Merve Yazıcı Kara, S. Balcı
ABS TRACT Objective: The Baska and the Protector Laryngeal masks are single-use second-generation supraglottic airway devices with a dual gastric channel. Material and Methods: 64 American Society of Anesthesiologists physical status 1-2 patients between the ages of 18-70 undergoing retrograde ureteroscopic surgery enrolled in this prospective randomized study. Results: Demographic airway variables and airway characteristics were similar between the groups. Insertion time was shorter in the Baska mask group [14 (11-20) versus 20 (13-27) seconds, p=0.035]. The need for optimization maneuvers during insertion was higher for the Baska mask group (p=0.009). The laryngeal mask airway (LMA) insertion was easier in the LMA Protector group (p=0.023). The first insertion success rate was 75% for the LMA Protector and 84% in the Baska mask. The total success rate of both devices was 91%. Nasogastric tube insertion was faster in the Baska mask group [14 (12-15) versus 17 (13-25) seconds; p=0.003]. Fiberoptic views were similar between the groups. Minute volume after insertion of the device was higher in the LMA Protector group [8 (6.5-10) L/min versus 6 (5-7) L/min; p<0.001]. Expiratory tidal volume was higher in the LMA Protector group after insertion of the device, 15 minutes, 30 minutes, and 45 minutes after insertion (p<0.001, p=0.032, p=0.001, p=0.027 respectively). The end-tidal sevoflurane concentration (ETsevo) 30 minutes after device insertion was higher in the Baska mask group (1.49±0.38 vs 1.75±0.36; p=0.014). Conclusion: The LMA Protector is superior to the Baska mask in providing higher tidal volumes and decreased need for optimization maneuvers in retrograde ureteroscopic surgery.
目的:Baska和Protector喉罩是具有双胃通道的第二代声门上气道装置。材料和方法:64名美国麻醉医师协会的身体状况1-2名年龄在18-70岁之间接受逆行输尿管镜手术的患者加入了这项前瞻性随机研究。结果:两组间气道人口学变量和气道特征相似。Baska面罩组插入时间较短[14 (11-20)vs 20(13-27)秒，p=0.035]。Baska面罩组在插入时对优化操作的需求更高(p=0.009)。喉罩保护器组更容易插入喉罩气道(LMA) (p=0.023)。LMA保护器的首次插入成功率为75%，Baska面罩的首次插入成功率为84%。两种设备的总成功率为91%。Baska面罩组鼻胃管插入速度更快[14(12-15)秒比17(13-25)秒;p = 0.003)。两组间的光纤图像相似。LMA保护器组插入装置后的分钟体积更高[8 (6.5-10)L/min vs 6 (5-7) L/min;p < 0.001)。LMA保护器组呼气潮气量在插入装置后15分钟、30分钟、45分钟较高(p<0.001, p=0.032, p=0.001, p=0.027)。Baska面罩组在装置插入后30分钟的潮末七氟醚浓度(ETsevo)较高(1.49±0.38 vs 1.75±0.36;p = 0.014)。结论:在逆行输尿管镜手术中，LMA保护器在提供更高的潮汐容量和减少优化操作需求方面优于Baska面罩。
{"title":"Comparison of the LMA Protector and the Baska Mask in Retrograde Ureteroscopic Surgery: A Prospective Randomized Clinical Study","authors":"Z. Arslan, Huri Yeşildal, Enes Malik Akdas, Merve Yazıcı Kara, S. Balcı","doi":"10.5336/anesthe.2022-94932","DOIUrl":"https://doi.org/10.5336/anesthe.2022-94932","url":null,"abstract":"ABS TRACT Objective: The Baska and the Protector Laryngeal masks are single-use second-generation supraglottic airway devices with a dual gastric channel. Material and Methods: 64 American Society of Anesthesiologists physical status 1-2 patients between the ages of 18-70 undergoing retrograde ureteroscopic surgery enrolled in this prospective randomized study. Results: Demographic airway variables and airway characteristics were similar between the groups. Insertion time was shorter in the Baska mask group [14 (11-20) versus 20 (13-27) seconds, p=0.035]. The need for optimization maneuvers during insertion was higher for the Baska mask group (p=0.009). The laryngeal mask airway (LMA) insertion was easier in the LMA Protector group (p=0.023). The first insertion success rate was 75% for the LMA Protector and 84% in the Baska mask. The total success rate of both devices was 91%. Nasogastric tube insertion was faster in the Baska mask group [14 (12-15) versus 17 (13-25) seconds; p=0.003]. Fiberoptic views were similar between the groups. Minute volume after insertion of the device was higher in the LMA Protector group [8 (6.5-10) L/min versus 6 (5-7) L/min; p<0.001]. Expiratory tidal volume was higher in the LMA Protector group after insertion of the device, 15 minutes, 30 minutes, and 45 minutes after insertion (p<0.001, p=0.032, p=0.001, p=0.027 respectively). The end-tidal sevoflurane concentration (ETsevo) 30 minutes after device insertion was higher in the Baska mask group (1.49±0.38 vs 1.75±0.36; p=0.014). Conclusion: The LMA Protector is superior to the Baska mask in providing higher tidal volumes and decreased need for optimization maneuvers in retrograde ureteroscopic surgery.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81363839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2022-94992
Hilal Zengin, Necdet İmaç
{"title":"Cross-Sectional Analysis of Dental Treatment Procedures Performed Under General Anesthesia or Sedation","authors":"Hilal Zengin, Necdet İmaç","doi":"10.5336/anesthe.2022-94992","DOIUrl":"https://doi.org/10.5336/anesthe.2022-94992","url":null,"abstract":"","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"119 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82579405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2023-96522
Meltem BEKTAŞ, Ela KADIOĞLU, Mert NAKİP, Mehmet ÇAKIRCA, Ayşe ÖZCAN, Çetin KAYMAK
Objective: Ischemia-reperfusion (I-R) injury is defined as the paradoxical exacerbation of cellular dysfunction and death following restoration of blood flow to ischemic tissues. In our study, it was aimed to examine the potential DNA injury effects of liver IR injury with an experimental animal model. Material and Methods: In the study, modeling was done with seven male New Zealand rabbits. Blood samples were taken before the experimental IR model, 30 minutes after ischemia, and 60 minutes after reperfusion. The DNA damage in the blood of the rabbits was measured using Tail Length, Intensity, and Moment techniques. Statistical significance was determined using one-way analysis of variance (ANOVA) and Tukey's post hoc test. Results: There are significant differences between control-ischemia, control-reperfusion and I-R groups in all 3 measurements. Tail length; increased by 51.84%, 54.16% after ischemia and reperfusion, respectively. Tail length increased by 134.09% between control and reperfusion. Similarly, tail density and tail moment were increased by 78.95% (after ischemia), 77.96% (after reperfusion), 85.54% (after ischemia), 165.52% (after reperfusion) respectively. Conclusion: Tissue blood flow disruption is known to occur tissue hypoxia that triggers anaerobic respiration. Restoring blood flow to a hypoxic-tissue results in an increase in reactive oxygen species production. Literature stated I/R-related DNA damage may result from the formation of oxygen radicals during the reperfusion period. Moreover, it induces oxidative damage and exceeds the antioxidative capacity of circulating leukocytes, leading to DNA damage. In our study, DNA lesions characteristic of DNA damage mediated by free radicals were detected at a significantly increased level during reperfusion.
{"title":"Effect of Liver Ischemia-Reperfusion Injury on Genotoxicity in Rabbits: Experimental Study","authors":"Meltem BEKTAŞ, Ela KADIOĞLU, Mert NAKİP, Mehmet ÇAKIRCA, Ayşe ÖZCAN, Çetin KAYMAK","doi":"10.5336/anesthe.2023-96522","DOIUrl":"https://doi.org/10.5336/anesthe.2023-96522","url":null,"abstract":"Objective: Ischemia-reperfusion (I-R) injury is defined as the paradoxical exacerbation of cellular dysfunction and death following restoration of blood flow to ischemic tissues. In our study, it was aimed to examine the potential DNA injury effects of liver IR injury with an experimental animal model. Material and Methods: In the study, modeling was done with seven male New Zealand rabbits. Blood samples were taken before the experimental IR model, 30 minutes after ischemia, and 60 minutes after reperfusion. The DNA damage in the blood of the rabbits was measured using Tail Length, Intensity, and Moment techniques. Statistical significance was determined using one-way analysis of variance (ANOVA) and Tukey's post hoc test. Results: There are significant differences between control-ischemia, control-reperfusion and I-R groups in all 3 measurements. Tail length; increased by 51.84%, 54.16% after ischemia and reperfusion, respectively. Tail length increased by 134.09% between control and reperfusion. Similarly, tail density and tail moment were increased by 78.95% (after ischemia), 77.96% (after reperfusion), 85.54% (after ischemia), 165.52% (after reperfusion) respectively. Conclusion: Tissue blood flow disruption is known to occur tissue hypoxia that triggers anaerobic respiration. Restoring blood flow to a hypoxic-tissue results in an increase in reactive oxygen species production. Literature stated I/R-related DNA damage may result from the formation of oxygen radicals during the reperfusion period. Moreover, it induces oxidative damage and exceeds the antioxidative capacity of circulating leukocytes, leading to DNA damage. In our study, DNA lesions characteristic of DNA damage mediated by free radicals were detected at a significantly increased level during reperfusion.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135754260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2022-90922
Ö. Canpolat, Melih Emre Bacanak, P. Karabacak, Hacı Ömer Osmanlioğlu, P. Kirdemi̇r
ABS
腹肌
{"title":"A Rare Syndrome After Intracranial Hemorrhage Operation: Ogilvie Syndrome","authors":"Ö. Canpolat, Melih Emre Bacanak, P. Karabacak, Hacı Ömer Osmanlioğlu, P. Kirdemi̇r","doi":"10.5336/anesthe.2022-90922","DOIUrl":"https://doi.org/10.5336/anesthe.2022-90922","url":null,"abstract":"ABS","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84852310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5336/anesthe.2022-91644
Onur PALABIYIK
Kafa travması nedeniyle oluşan travmatik beyin hasarı (TBH) yüksek morbidite ve mortalite ile seyreden ciddi bir sağlık sorunudur. TBH'de tedavi arayışları sürecinde nöroproteksiyon sağlamak amacıyla birçok farmakolojik ajan uygulanmıştır. Amantadin, N-metil D-aspartat reseptörlerine antagonist etkisi yanında dopaminerjik reseptörlere de direkt agonistik etkisiyle nöroproteksiyon sağlamaktadır. Yoğun bakım ünitesinde, Glasgow Koma Skoru (GKS) 10'un altında olan 16- 72 yaş arasındaki 5 kafa travmalı hastaya standart tedaviye ek olarak amantadin protokolü (ilk hafta 200 mg/gün intravenöz infüzyon şeklinde, 2. hafta 200 mg/gün enteral yoldan, 3 ve 4. haftalarda ise 400 mg/gün enteral yoldan) uygulandı. Amantadin tedavisi ile GKS ve Güncellenmiş Komadan Çıkma Skalası skorlarında artış, Sakatlık Derecelendirme Ölçeği skorunda azalma saptandı. Sonuç olarak, TBH gelişmiş hastalarda amantadinin klinik ve nörofonksiyonel olarak iyileşmeye katkı sağladığını düşünmekteyiz.
{"title":"Neurocognitive Recovery with Amantadine in Intensive Care Unit Patients with Head Trauma: Case Series","authors":"Onur PALABIYIK","doi":"10.5336/anesthe.2022-91644","DOIUrl":"https://doi.org/10.5336/anesthe.2022-91644","url":null,"abstract":"Kafa travması nedeniyle oluşan travmatik beyin hasarı (TBH) yüksek morbidite ve mortalite ile seyreden ciddi bir sağlık sorunudur. TBH'de tedavi arayışları sürecinde nöroproteksiyon sağlamak amacıyla birçok farmakolojik ajan uygulanmıştır. Amantadin, N-metil D-aspartat reseptörlerine antagonist etkisi yanında dopaminerjik reseptörlere de direkt agonistik etkisiyle nöroproteksiyon sağlamaktadır. Yoğun bakım ünitesinde, Glasgow Koma Skoru (GKS) 10'un altında olan 16- 72 yaş arasındaki 5 kafa travmalı hastaya standart tedaviye ek olarak amantadin protokolü (ilk hafta 200 mg/gün intravenöz infüzyon şeklinde, 2. hafta 200 mg/gün enteral yoldan, 3 ve 4. haftalarda ise 400 mg/gün enteral yoldan) uygulandı. Amantadin tedavisi ile GKS ve Güncellenmiş Komadan Çıkma Skalası skorlarında artış, Sakatlık Derecelendirme Ölçeği skorunda azalma saptandı. Sonuç olarak, TBH gelişmiş hastalarda amantadinin klinik ve nörofonksiyonel olarak iyileşmeye katkı sağladığını düşünmekteyiz.","PeriodicalId":23442,"journal":{"name":"Turkiye Klinikleri Journal of Anesthesiology Reanimation","volume":"280 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135754531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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