Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.abs26-11.x
A. Testa, M. Ciampelli, C. Mastromarino, R. Lopez, D. Basso, M. Distefano, A. Poerio, G. Scambia
The treatment and prognosis of cervical cancer depends on the clinical stage based on the FIGO classification and the presence of lymph node metastases. Clinical staging of cervical cancer does not attain a good diagnostic performance, since it is incorrect in approximately one‐third of patients who undergo surgical staging. Magnetic resonance (MR) imaging resulted to be superior to clinical evaluation and computed tomography (CT) in parametrial evaluation and in the staging of uterine cervical carcinoma. Endoluminal ultrasound was introduced to analyse the cervix but no improvement in the diagnostic accuracy with respect to clinical staging was obtained. Color Doppler velocimetry was proposed as a non‐invasive tool in the examination of cervical cancer. Cervical cancers with detectable intratumoral blood flow were associated with larger size, invasion of parametrium, pelvic lymph node metastases and greater microvessel density. A ‘vascularity index’ resulted to be correlated with staging and lymph node metastases. The aims of our study were to assess color Doppler characteristics of 48 cervical cancers at different stages and to analyse the correlation between Doppler parameters and clinical–pathological features of the tumors. Three‐dimensional color power Doppler technique was used to investigate the vascular architecture of the neoplastic tissue. Three‐dimensional vascular images were compared to magnetic resonance results. The actual clinical application of the three‐dimensional vascular analysis in the evaluation of cervical cancers remains still to be defined.
{"title":"Color Doppler in the assessment of cervical cancer","authors":"A. Testa, M. Ciampelli, C. Mastromarino, R. Lopez, D. Basso, M. Distefano, A. Poerio, G. Scambia","doi":"10.1046/j.1469-0705.2001.abs26-11.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.abs26-11.x","url":null,"abstract":"The treatment and prognosis of cervical cancer depends on the clinical stage based on the FIGO classification and the presence of lymph node metastases. Clinical staging of cervical cancer does not attain a good diagnostic performance, since it is incorrect in approximately one‐third of patients who undergo surgical staging. Magnetic resonance (MR) imaging resulted to be superior to clinical evaluation and computed tomography (CT) in parametrial evaluation and in the staging of uterine cervical carcinoma. Endoluminal ultrasound was introduced to analyse the cervix but no improvement in the diagnostic accuracy with respect to clinical staging was obtained. Color Doppler velocimetry was proposed as a non‐invasive tool in the examination of cervical cancer. Cervical cancers with detectable intratumoral blood flow were associated with larger size, invasion of parametrium, pelvic lymph node metastases and greater microvessel density. A ‘vascularity index’ resulted to be correlated with staging and lymph node metastases. The aims of our study were to assess color Doppler characteristics of 48 cervical cancers at different stages and to analyse the correlation between Doppler parameters and clinical–pathological features of the tumors. Three‐dimensional color power Doppler technique was used to investigate the vascular architecture of the neoplastic tissue. Three‐dimensional vascular images were compared to magnetic resonance results. The actual clinical application of the three‐dimensional vascular analysis in the evaluation of cervical cancers remains still to be defined.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86187726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.0180S1024.x
F. Chan, S. Wong, R. Cincotta, A. Parry, A. Welsh, M. Stone, D. Cooper
Purpose: To assess the detection rate for congenital malformations in a routine ultrasound screening program in a tertiary Australian institution.
目的:评估先天性畸形的检出率在常规超声筛查程序在澳大利亚的高等院校。
{"title":"Routine ultrasound screening in 12169 pregnancies","authors":"F. Chan, S. Wong, R. Cincotta, A. Parry, A. Welsh, M. Stone, D. Cooper","doi":"10.1046/j.1469-0705.2001.0180S1024.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.0180S1024.x","url":null,"abstract":"Purpose: To assess the detection rate for congenital malformations in a routine ultrasound screening program in a tertiary Australian institution.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73204024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.abs26-19.x
T.‐C. Hsieh, G.‐P. Yeh
Background: Nuchal translucency (NT) has been used successfully in screening for chromosomal abnormalities at 11–14 weeks of gestation. Increased NT thickness is also associated with lots of fetal anomalies in chromosomally normal fetuses. We report a case of osteogenesis imperfecta (OI), type II, presenting with increased NT thickness. A 26‐year‐old Taiwanese woman, gravida 2, para 1, without medical or family history was scanned for confirmation of menstrual gestational age at 13 weeks of gestation. Crown‐rump length was compatible with menstrual age. Increased NT thickness was noted (3.6 mm). Follow up scan 2 weeks later revealed hypomineralization of skull, multiple fractures of long bones and ribs and severe micromelia. A presumptive diagnosis of OI type II was made based on sonographic findings. After counseling, the parents decided to terminate the pregnancy. A stillborn weighing 70 g was delivered after intravaginal misoprostol application. Postmortem radiograph and autopsy confirmed the diagnosis of OI.
{"title":"Fetus with osteogenesis imperfecta presenting as increased nuchal translucency thickness in the first trimester: a case report","authors":"T.‐C. Hsieh, G.‐P. Yeh","doi":"10.1046/j.1469-0705.2001.abs26-19.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.abs26-19.x","url":null,"abstract":"Background: Nuchal translucency (NT) has been used successfully in screening for chromosomal abnormalities at 11–14 weeks of gestation. Increased NT thickness is also associated with lots of fetal anomalies in chromosomally normal fetuses. We report a case of osteogenesis imperfecta (OI), type II, presenting with increased NT thickness. A 26‐year‐old Taiwanese woman, gravida 2, para 1, without medical or family history was scanned for confirmation of menstrual gestational age at 13 weeks of gestation. Crown‐rump length was compatible with menstrual age. Increased NT thickness was noted (3.6 mm). Follow up scan 2 weeks later revealed hypomineralization of skull, multiple fractures of long bones and ribs and severe micromelia. A presumptive diagnosis of OI type II was made based on sonographic findings. After counseling, the parents decided to terminate the pregnancy. A stillborn weighing 70 g was delivered after intravaginal misoprostol application. Postmortem radiograph and autopsy confirmed the diagnosis of OI.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89538512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.abs27-39.x
C. Karidas, P. Anastassopoulos, D. Perry, D. Economides
Thromboelastography (TEG) is a method of monitoring global homeostatic function as a dynamic process, involving the interaction between the protein coagulation cascade and platelets, as opposed to the isolated end points measured by conventional coagulation screens. The purpose of this study is to determine whether TEG variables can be used in the second trimester to predict the development of adverse pregnancy outcomes such as pre‐eclampsia and intrauterine growth restriction (IUGR defined as birth weight below the 5th centile for gestational age).
{"title":"Thromboelastography in the second trimester of pregnancy in the prediction of adverse pregnancy outcome","authors":"C. Karidas, P. Anastassopoulos, D. Perry, D. Economides","doi":"10.1046/j.1469-0705.2001.abs27-39.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.abs27-39.x","url":null,"abstract":"Thromboelastography (TEG) is a method of monitoring global homeostatic function as a dynamic process, involving the interaction between the protein coagulation cascade and platelets, as opposed to the isolated end points measured by conventional coagulation screens. The purpose of this study is to determine whether TEG variables can be used in the second trimester to predict the development of adverse pregnancy outcomes such as pre‐eclampsia and intrauterine growth restriction (IUGR defined as birth weight below the 5th centile for gestational age).","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88386778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.abs27-7.x
P. Rozpravka, A. Ostro
Objective: To state clinical signification of differentiated evaluation Doppler velocimetry middle cerebral artery (MCA) of ultrasonographically detected intrauterine growth retarded (IUGR) fetuses, during pregnancies complicated hypertension (PIH) and pre‐eclampsia.
{"title":"Differentiated evaluation of blood flow middle cerebral artery in relation to the fetal well‐being","authors":"P. Rozpravka, A. Ostro","doi":"10.1046/j.1469-0705.2001.abs27-7.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.abs27-7.x","url":null,"abstract":"Objective: To state clinical signification of differentiated evaluation Doppler velocimetry middle cerebral artery (MCA) of ultrasonographically detected intrauterine growth retarded (IUGR) fetuses, during pregnancies complicated hypertension (PIH) and pre‐eclampsia.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91492838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.abs28-44.x
F. Chan, J. Clouston, R. Cincotta, P. Borzi
Background: Highly vascular fetal tumors can lead to death before viability as a result of vascular steal syndrome. Open fetal surgery is associated with significant risks for prematurity and maternal morbidity. Various local ablative techniques have been tried to reduce tumor vascularity, with variable success. Radiofrequency ablation has been performed for sacrococcygeal teratoma, but cervical teratoma poise further significant challenges with its proximity to vital neck structures.
{"title":"Radiofrequency ablation of fetal cervical teratoma","authors":"F. Chan, J. Clouston, R. Cincotta, P. Borzi","doi":"10.1046/j.1469-0705.2001.abs28-44.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.abs28-44.x","url":null,"abstract":"Background: Highly vascular fetal tumors can lead to death before viability as a result of vascular steal syndrome. Open fetal surgery is associated with significant risks for prematurity and maternal morbidity. Various local ablative techniques have been tried to reduce tumor vascularity, with variable success. Radiofrequency ablation has been performed for sacrococcygeal teratoma, but cervical teratoma poise further significant challenges with its proximity to vital neck structures.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85302090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.0180S1049.x
A. Malvasi, P. Totaro, L. Liaci, M. D'Ambrosio, V. Traina
Purpose: In our Department of Obstetrics, where 1600 deliveries are carried out on average every year, cesarean section (c.s.) with Misgav Ladach methods has been practiced since November 1995, for 2078 cases in all. In our study, we have examined sonographically 309 repeat c.s. with Misgav Ladach methods compared to 318 traditional repeat c.s. The aim of our investigation is the sonographic examination of patients with open peritoneum and those with closed peritoneum to discriminate the frequency of bladder flap hematomas and other complications in the two techniques.
{"title":"Sonographic examination of puerperal uterus after repeat cesarean section with traditional and Misgav Ladach methods","authors":"A. Malvasi, P. Totaro, L. Liaci, M. D'Ambrosio, V. Traina","doi":"10.1046/j.1469-0705.2001.0180S1049.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.0180S1049.x","url":null,"abstract":"Purpose: In our Department of Obstetrics, where 1600 deliveries are carried out on average every year, cesarean section (c.s.) with Misgav Ladach methods has been practiced since November 1995, for 2078 cases in all. In our study, we have examined sonographically 309 repeat c.s. with Misgav Ladach methods compared to 318 traditional repeat c.s. The aim of our investigation is the sonographic examination of patients with open peritoneum and those with closed peritoneum to discriminate the frequency of bladder flap hematomas and other complications in the two techniques.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76425813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.abs20-4.x
A. Hull, D. Pretorius, R. Newton, G. James
Purpose: To assess awareness and attitudes towards the use of 3DUS in obstetrics in a group of medical professionals attending a national imaging conference.
目的:了解参加全国影像学会议的一组医学专业人员对3DUS在产科应用的认识和态度。
{"title":"Sonographers and sonologists hold favorable views of the role of three‐dimensional ultrasound (3DUS) in obstetrics following a formal lecture on the subject","authors":"A. Hull, D. Pretorius, R. Newton, G. James","doi":"10.1046/j.1469-0705.2001.abs20-4.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.abs20-4.x","url":null,"abstract":"Purpose: To assess awareness and attitudes towards the use of 3DUS in obstetrics in a group of medical professionals attending a national imaging conference.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75243002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.abs28-46.x
G. Fait, J. Har-Toov, I. Gull, R. Amster, I. Wolman, J. Lessing, A. Jaffa
The importance of fluid analysis in the evaluation of intraperitoneal cysts in female fetuses is demonstrated. Case 1: A 30‐year‐old woman had an unremarkable pregnancy until 29 gestational weeks, when a routine US examination revealed an anechoic cyst of 4.0 cm in diameter located in the lower abdomen of a female fetus. At 33 weeks of gestation the cyst enlarged to 6.5 cm. Intrauterine aspiration of the cyst was performed. A volume of 75 mL of yellow fluid was obtained and collapse of the cyst was noted. Fluid biochemistry revealed estradiol >200000 pg/mL, progesterone 1648 ng/mL, creatinine undetectable. A fetal ovarian cyst was diagnosed. At 34 weeks of gestation the cyst enlarged again to 6 cm and 78 mL of yellow fluid was obtained on intrauterine aspiration. Again, collapse of the cyst was noted on US. Repeated scans until birth showed an anechoic cyst of 4.0 cm. Postnatal abdominal US confirmed the diagnosis and a complete disappearance of the cyst after 2 weeks. Case 2: A 28‐year‐old woman had an unremarkable pregnancy until 34 gestational weeks, when a routine US examination revealed an anechoic cyst of 6.0 cm in diameter located in the lower abdomen of a female fetus. Intrauterine aspiration of the cyst was performed. A volume of 147 mL of yellow fluid were obtained and collapse of the cyst was noted. Fluid biochemistry revealed estradiol 781 pg/mL, progesterone 37 ng/mL, and creatinine 4 mg/dL. An unusual urinary tract malformation was diagnosed. Repeated scans until birth showed an anechoic cyst of 6 cm. After delivery a fistula between the urinary bladder and the upper vagina, and an imperforated hymen, were diagnosed. In cases of prenatal needle aspiration, fluid biochemistry may be helpful to establish the origin of intraperitoneal cysts in the female fetus, especially when recurrence occurs, and prevent unnecessary attempt of decompression of intraperitoneal cysts.
{"title":"The importance of fluid analysis in fetal intra‐abdominal cyst aspiration","authors":"G. Fait, J. Har-Toov, I. Gull, R. Amster, I. Wolman, J. Lessing, A. Jaffa","doi":"10.1046/j.1469-0705.2001.abs28-46.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.abs28-46.x","url":null,"abstract":"The importance of fluid analysis in the evaluation of intraperitoneal cysts in female fetuses is demonstrated. Case 1: A 30‐year‐old woman had an unremarkable pregnancy until 29 gestational weeks, when a routine US examination revealed an anechoic cyst of 4.0 cm in diameter located in the lower abdomen of a female fetus. At 33 weeks of gestation the cyst enlarged to 6.5 cm. Intrauterine aspiration of the cyst was performed. A volume of 75 mL of yellow fluid was obtained and collapse of the cyst was noted. Fluid biochemistry revealed estradiol >200000 pg/mL, progesterone 1648 ng/mL, creatinine undetectable. A fetal ovarian cyst was diagnosed. At 34 weeks of gestation the cyst enlarged again to 6 cm and 78 mL of yellow fluid was obtained on intrauterine aspiration. Again, collapse of the cyst was noted on US. Repeated scans until birth showed an anechoic cyst of 4.0 cm. Postnatal abdominal US confirmed the diagnosis and a complete disappearance of the cyst after 2 weeks. Case 2: A 28‐year‐old woman had an unremarkable pregnancy until 34 gestational weeks, when a routine US examination revealed an anechoic cyst of 6.0 cm in diameter located in the lower abdomen of a female fetus. Intrauterine aspiration of the cyst was performed. A volume of 147 mL of yellow fluid were obtained and collapse of the cyst was noted. Fluid biochemistry revealed estradiol 781 pg/mL, progesterone 37 ng/mL, and creatinine 4 mg/dL. An unusual urinary tract malformation was diagnosed. Repeated scans until birth showed an anechoic cyst of 6 cm. After delivery a fistula between the urinary bladder and the upper vagina, and an imperforated hymen, were diagnosed. In cases of prenatal needle aspiration, fluid biochemistry may be helpful to establish the origin of intraperitoneal cysts in the female fetus, especially when recurrence occurs, and prevent unnecessary attempt of decompression of intraperitoneal cysts.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83453917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-10-01DOI: 10.1046/j.1469-0705.2001.abs28-18.x
K. Kepkep, H. Gurpinar, E. Kar
Introduction: Preterm delivery has been faced in all delivery with a 7–11% and it keeps its importance by causing perinatal mortality and morbidity. Therefore it is important to define preterm delivery risk during the earlier period of the delivery.
{"title":"Evaluation of the effects of cervical properties","authors":"K. Kepkep, H. Gurpinar, E. Kar","doi":"10.1046/j.1469-0705.2001.abs28-18.x","DOIUrl":"https://doi.org/10.1046/j.1469-0705.2001.abs28-18.x","url":null,"abstract":"Introduction: Preterm delivery has been faced in all delivery with a 7–11% and it keeps its importance by causing perinatal mortality and morbidity. Therefore it is important to define preterm delivery risk during the earlier period of the delivery.","PeriodicalId":23453,"journal":{"name":"Ultrasound in Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80971325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}