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Feasibility and acceptability of randomized controlled trial of intervention vs expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy. 单绒毛膜双胎妊娠早发性选择性胎儿生长限制干预与期待治疗的随机对照试验的可行性和可接受性。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-01-24 DOI: 10.1002/uog.29175
A Khalil, S Prasad, J J Kirkham, R Jackson, K Woolfall
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引用次数: 0
Prediction of small-for-gestational age and fetal growth restriction at routine ultrasound examination at 35-37 weeks' gestation. 妊娠35 ~ 37周常规超声检查对小胎龄和胎儿生长限制的预测。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-04-26 DOI: 10.1002/uog.29223
M Lopian, S Prasad, E Segal, A Dotan, C O Ulusoy, A Khalil
<p><strong>Objective: </strong>To evaluate the performance of sonographic fetal biometry and Doppler parameters assessed at routine third-trimester ultrasound examination for predicting small-for-gestational age (SGA) and fetal growth restriction (FGR).</p><p><strong>Methods: </strong>This was a retrospective cohort study of low-risk singleton pregnancies undergoing routine ultrasound examination between 35 + 0 and 37 + 6 weeks' gestation and delivered at St George's University Hospital, London, UK, between December 2019 and February 2024. The study outcomes were SGA (birth weight < 5<sup>th</sup> centile) and FGR (birth weight < 3<sup>rd</sup> centile or birth weight < 10<sup>th</sup> centile with composite adverse perinatal outcome). Composite adverse perinatal outcome comprised intrauterine death, neonatal death or admission to the neonatal intensive care unit. Demographic characteristics, estimated fetal weight (EFW) and abdominal circumference centiles, as well as Doppler indices, including pulsatility indices (PI) of the umbilical artery (UA), middle cerebral artery (MCA) and uterine artery (UtA) were evaluated. The cerebroplacental ratio (CPR) was calculated, and all indices were converted to multiples of the median (MoM). Multivariable logistic regression analysis was performed to identify and adjust for confounders. The area under the receiver-operating-characteristics curve (AUC) was used to evaluate the model's performance for predicting small neonates.</p><p><strong>Results: </strong>A total of 14 161 pregnancies were included in the study. The prevalence of SGA and FGR neonates was 3.1% and 1.5%, respectively. Independent predictors of SGA and FGR, respectively, were: EFW centile (adjusted odds ratio (aOR) 0.91 (95% CI, 0.90-0.92); P < 0.001 and aOR 0.90 (95% CI, 0.89-0.91); P < 0.001); AC centile (aOR 0.91 (95% CI, 0.90-0.92); P < 0.001 and aOR 0.91 (95% CI, 0.90-0.92); P <0.001); UA-PI MoM (aOR 4.60 (95% CI, 2.19-9.64); P < 0.001 and aOR 2.53 (95% CI, 1.05-6.10); P = 0.038); MCA-PI MoM (aOR 0.37 (95% CI, 0.20-0.70); P = 0.002 and aOR 0.26 (95% CI, 0.12-0.59); P = 0.001); CPR MoM (aOR 0.23 (95% CI, 0.13-0.42); P < 0.001 and aOR 0.25 (95% CI, 0.12-0.53); P < 0.001); and UtA-PI MoM (aOR 2.54 (95% CI, 1.68-3.83); P < 0.001 and aOR 2.16 (95% CI, 1.31-3.58); P = 0.003). The EFW centile alone was associated with an AUC of 0.917 (95% CI, 0.907-0.929) for the prediction of SGA and 0.925 (95% CI, 0.908-0.939) for the prediction of FGR. This was similar to AUCs of around 0.92 for the prediction of SGA and AUCs of around 0.93 for the prediction of FGR when the EFW centile was combined with any Doppler parameters.</p><p><strong>Conclusions: </strong>Sonographic fetal biometry evaluation in the late third trimester can predict delivery of a neonate affected by SGA or FGR, including those at risk for adverse perinatal outcomes. In an unselected population, fetal arterial Doppler parameters were independent predictors of SGA and FGR, but the addit
目的:探讨超声胎儿生物测量及多普勒参数在妊娠晚期常规超声检查中预测小胎龄(SGA)和胎儿生长受限(FGR)的价值。方法:对2019年12月至2024年2月在英国伦敦圣乔治大学医院进行常规超声检查的35 + 0 ~ 37 + 6周低风险单胎妊娠进行回顾性队列研究。研究结果为SGA(出生体重百分位数)和FGR(出生体重百分位数或出生体重百分位数合并围产期不良结局)。围产期综合不良结局包括宫内死亡、新生儿死亡或入住新生儿重症监护病房。评估人口统计学特征、估计胎儿体重(EFW)和腹围百分数,以及多普勒指数,包括脐动脉(UA)、大脑中动脉(MCA)和子宫动脉(UtA)的脉搏指数(PI)。计算脑胎盘比(CPR),并将所有指标换算为中位数(MoM)的倍数。采用多变量逻辑回归分析来识别和调整混杂因素。采用受试者工作特征曲线下面积(AUC)评价模型预测小新生儿的效果。结果:本研究共纳入14161例妊娠。SGA和FGR新生儿的患病率分别为3.1%和1.5%。SGA和FGR的独立预测因子分别为:EFW百分位数(校正优势比(aOR) 0.91 (95% CI, 0.90-0.92);结论:妊娠晚期超声胎儿生物测量评估可以预测受SGA或FGR影响的新生儿的分娩,包括那些有不良围产期结局风险的新生儿。在未选择的人群中,胎儿动脉多普勒参数是SGA和FGR的独立预测指标,但在胎儿生物测定中加入多普勒参数并不能提高对小新生儿发生率的预测。©2025作者。妇产科学超声由John Wiley & Sons Ltd代表国际妇产科学超声学会出版。
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引用次数: 0
Ultrasound-guided cyst aspiration for management of acute adnexal torsion. 超声引导下囊肿抽吸治疗急性附件扭转。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-04-26 DOI: 10.1002/uog.29225
L Berg, N Eagles, S Kastora, J Farren, J Naftalin, D Jurkovic

Objective: Ultrasound-guided cyst aspiration is a potential treatment for acute adnexal torsion that can be performed in the outpatient setting, offering an alternative to emergency laparoscopic surgery. The objective of this study was to describe our initial experience with aspiration of acutely torted adnexal cysts.

Methods: This was a retrospective single-center study, in which we identified all patients who underwent ultrasound-guided cyst aspiration in our center between February 2008 and September 2023. Indications for the procedure were ultrasound diagnosis of adnexal torsion due to an ovarian cyst and clinical symptoms of acute adnexal torsion. Success was defined as the avoidance of emergency surgery for adnexal torsion related to the same cyst. We extracted clinical data, ultrasound scan findings, procedural details and clinical outcomes from our clinical database.

Results: Overall, 46 patients underwent ultrasound-guided cyst aspiration for the management of adnexal torsion, 24 (52%) of whom were pregnant. At ultrasound examination, all 46 cysts had unilocular morphology, and in 96% (44/46) of cases, the cyst content was anechoic. Cyst aspiration was performed transabdominally in 30 (65%) patients and transvaginally in 16 (35%) patients. A total of 39 (85%) patients experienced complete resolution of symptoms immediately after ultrasound-guided cyst aspiration. One procedure was abandoned owing to patient discomfort and six (13%) patients reported non-resolution or short-term recurrence of symptoms, necessitating emergency laparoscopy in seven patients. No complications occurred as a result of ultrasound-guided cyst aspiration. Three patients had cyst aspiration more than once. Follow-up data were available for 29/39 (74%) patients who had successful ultrasound-guided cyst aspiration and received a subsequent ultrasound assessment in our clinic. In 8/29 (28%) patients, the cyst had completely resolved. In total, 4/21 (19%) patients with a persistent cyst opted for elective surgical intervention, while 17/21 (81%) continued conservative management at the last follow-up. Overall, 25/29 (86%) of those followed up after successful ultrasound-guided cyst aspiration, and at least 25/46 (54%) of all patients, avoided any form of surgical treatment.

Conclusions: Ultrasound-guided cyst aspiration is an effective treatment for the management of acute adnexal torsion due to a cyst with unilocular morphology and anechoic or hypoechoic fluid content. With the use of this technique, emergency hospital admission and surgery were avoided in the majority of patients. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

目的:超声引导下的囊肿抽吸是急性附件扭转的一种潜在治疗方法,可在门诊进行,为急诊腹腔镜手术提供了一种替代方法。本研究的目的是描述我们对急性附件囊肿抽吸的初步经验。方法:这是一项回顾性单中心研究,我们确定了2008年2月至2023年9月期间在我们中心接受超声引导囊肿抽吸的所有患者。手术的适应症是超声诊断卵巢囊肿引起的附件扭转和急性附件扭转的临床症状。成功的定义是避免了同一囊肿相关的附件扭转的紧急手术。我们从临床数据库中提取临床数据、超声扫描结果、手术细节和临床结果。结果:46例患者接受超声引导囊肿抽吸治疗附件扭转,其中24例(52%)为孕妇。超声检查,46例囊肿均为单室形态,96%(44/46)的囊肿内容物无回声。囊肿抽吸30例(65%)经腹,16例(35%)经阴道。39例(85%)患者在超声引导下囊肿抽吸后症状立即完全缓解。1例因患者不适而放弃手术,6例(13%)患者报告症状未缓解或短期复发,7例患者需要紧急腹腔镜检查。超声引导下的囊肿穿刺无并发症发生。3例患者有一次以上的囊肿抽吸。39例患者中有29例(74%)在超声引导下囊肿抽吸成功,并在我们的诊所接受了后续超声评估。在8/29(28%)患者中,囊肿完全溶解。最后一次随访时,4/21(19%)持续性囊肿患者选择择期手术治疗,17/21(81%)患者继续保守治疗。总体而言,25/29(86%)的超声引导囊肿抽吸成功后随访,至少25/46(54%)的患者避免了任何形式的手术治疗。结论:超声引导下的囊肿抽吸是治疗单眼形态囊肿和低回声或低回声液体含量所致急性附件扭转的有效方法。使用该技术,大多数患者避免了急诊住院和手术。©2025作者。妇产科学超声由John Wiley & Sons Ltd代表国际妇产科学超声学会出版。
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引用次数: 0
Prevention of preterm birth in twin pregnancy: international Delphi consensus. 双胎妊娠预防早产:国际德尔菲共识。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-04-18 DOI: 10.1002/uog.29220
H J Mustafa, J Sheikh, V Berghella, W A Grobman, A A Shamshirsaz, S J Gordijn, W Ganzevoort, A Roman, A Khalil

Objective: To use the Delphi method to gain insight into approaches to prenatal diagnosis and management of preterm birth (PTB) in twin pregnancies, including complications such as twin-to-twin transfusion syndrome (TTTS) and a short and/or dilated cervix.

Methods: A three-round Delphi process was conducted among an international panel of experts to assess their approach to prevention, monitoring and management strategies for PTB in twin pregnancies. Experts were selected based on their publication record or membership of related organizations. Response options were multiple-choice answers or a five-point Likert scale. A priori, a cut-off of ≥ 70% agreement was used to define consensus.

Results: A total of 117 experts participated in the first round, of whom 94/117 (80.3%) completed all subsequent rounds. Representatives came from at least 22 countries (across five continents), most commonly the USA (50.4%) and the UK (12.0%). Over 70% of experts performed routine screening of cervical length (CL) using transvaginal ultrasound at 18-23 weeks' gestation, using CL ≤ 25 mm to diagnose short cervix in twin pregnancies, regardless of a history of PTB. In twin pregnancies with a short non-dilated cervix, most experts offered vaginal progesterone rather than pessary or cervical cerclage, regardless of a history of PTB. In twin pregnancies with asymptomatic dilated cervix, consensus was reached (88.3% agreement) for placement of cervical cerclage, performed up to 24 weeks' gestation (67.5% agreement; no consensus). Similarly, 96.1% of experts agreed that performing serial transvaginal ultrasound measurements of CL at 16-24 weeks' gestation was warranted in women with a current singleton pregnancy who had a previous twin pregnancy that required physical examination-indicated cerclage; these patients should be considered high risk for PTB (83.1% agreement). In twin pregnancies with TTTS, laser surgery is offered by most experts, regardless of preoperative CL. In patients with TTTS and short CL, most experts would recommend cervical cerclage (71.9%) or vaginal progesterone (65.6%) rather than pessary or expectant management. However, no consensus was reached on measures to prevent PTB in cases of TTTS with cervical dilation.

Conclusions: This Delphi consensus study highlights practice variations among healthcare providers worldwide in the evaluation and management of PTB in twin pregnancies, which often differ from recommendations given by national and international societies. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

目的:采用德尔菲法探讨双胎妊娠早产(PTB)的产前诊断和处理方法,包括双胎输血综合征(TTTS)和宫颈短和/或宫颈扩张等并发症。方法:在一个国际专家小组中进行了三轮德尔菲过程,以评估他们对双胎妊娠PTB的预防、监测和管理策略的方法。专家是根据他们的出版记录或相关组织的成员资格来选择的。回答选项为多项选择题或李克特五分制。先验地,一致度≥70%的临界值被用来定义共识。结果:共有117名专家参加了第一轮评审,其中94/117人(80.3%)完成了后续的所有评审。代表来自至少22个国家(横跨五大洲),最常见的是美国(50.4%)和英国(12.0%)。超过70%的专家在妊娠18-23周使用经阴道超声进行宫颈长度(CL)常规筛查,使用CL≤25 mm诊断双胎妊娠宫颈短,无论是否有PTB病史。对于短宫颈未扩张的双胎妊娠,无论是否有PTB病史,大多数专家都会提供阴道黄体酮而不是子宫内膜或宫颈环扎术。在无症状宫颈扩张的双胎妊娠中,达成共识(88.3%同意)放置宫颈环扎术,直至妊娠24周(67.5%同意;没有共识)。同样,96.1%的专家同意,在妊娠16-24周时,对当前单胎妊娠、曾有双胎妊娠且需要体格检查提示有结扎的妇女进行连续阴道超声检查是有必要的;这些患者应被认为是PTB的高风险患者(83.1%同意)。对于患有TTTS的双胎妊娠,大多数专家都提供激光手术,无论术前CL如何。对于TTTS和短期CL患者,大多数专家会推荐宫颈环扎术(71.9%)或阴道黄体酮(65.6%),而不是子宫内膜或预期治疗。然而,在TTTS伴宫颈扩张的病例中预防肺结核的措施上没有达成共识。结论:德尔菲共识研究强调了世界各地医疗服务提供者在评估和管理双胎妊娠肺结核方面的实践差异,这些差异通常与国家和国际社会给出的建议不同。©2025作者。妇产科学超声由John Wiley & Sons Ltd代表国际妇产科学超声学会出版。
{"title":"Prevention of preterm birth in twin pregnancy: international Delphi consensus.","authors":"H J Mustafa, J Sheikh, V Berghella, W A Grobman, A A Shamshirsaz, S J Gordijn, W Ganzevoort, A Roman, A Khalil","doi":"10.1002/uog.29220","DOIUrl":"10.1002/uog.29220","url":null,"abstract":"<p><strong>Objective: </strong>To use the Delphi method to gain insight into approaches to prenatal diagnosis and management of preterm birth (PTB) in twin pregnancies, including complications such as twin-to-twin transfusion syndrome (TTTS) and a short and/or dilated cervix.</p><p><strong>Methods: </strong>A three-round Delphi process was conducted among an international panel of experts to assess their approach to prevention, monitoring and management strategies for PTB in twin pregnancies. Experts were selected based on their publication record or membership of related organizations. Response options were multiple-choice answers or a five-point Likert scale. A priori, a cut-off of ≥ 70% agreement was used to define consensus.</p><p><strong>Results: </strong>A total of 117 experts participated in the first round, of whom 94/117 (80.3%) completed all subsequent rounds. Representatives came from at least 22 countries (across five continents), most commonly the USA (50.4%) and the UK (12.0%). Over 70% of experts performed routine screening of cervical length (CL) using transvaginal ultrasound at 18-23 weeks' gestation, using CL ≤ 25 mm to diagnose short cervix in twin pregnancies, regardless of a history of PTB. In twin pregnancies with a short non-dilated cervix, most experts offered vaginal progesterone rather than pessary or cervical cerclage, regardless of a history of PTB. In twin pregnancies with asymptomatic dilated cervix, consensus was reached (88.3% agreement) for placement of cervical cerclage, performed up to 24 weeks' gestation (67.5% agreement; no consensus). Similarly, 96.1% of experts agreed that performing serial transvaginal ultrasound measurements of CL at 16-24 weeks' gestation was warranted in women with a current singleton pregnancy who had a previous twin pregnancy that required physical examination-indicated cerclage; these patients should be considered high risk for PTB (83.1% agreement). In twin pregnancies with TTTS, laser surgery is offered by most experts, regardless of preoperative CL. In patients with TTTS and short CL, most experts would recommend cervical cerclage (71.9%) or vaginal progesterone (65.6%) rather than pessary or expectant management. However, no consensus was reached on measures to prevent PTB in cases of TTTS with cervical dilation.</p><p><strong>Conclusions: </strong>This Delphi consensus study highlights practice variations among healthcare providers worldwide in the evaluation and management of PTB in twin pregnancies, which often differ from recommendations given by national and international societies. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</p>","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"712-722"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiomics analysis of solid adnexal masses - a step towards automated ultrasound diagnosis. 固体附件肿块的放射组学分析——迈向自动超声诊断的一步。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-05-22 DOI: 10.1002/uog.29252
Y-J Ye, P An
{"title":"Radiomics analysis of solid adnexal masses - a step towards automated ultrasound diagnosis.","authors":"Y-J Ye, P An","doi":"10.1002/uog.29252","DOIUrl":"10.1002/uog.29252","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"805-806"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply. 回复。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-05-22 DOI: 10.1002/uog.29254
F Moro, M Vagni, H E Tran, L Boldrini, A Fagotti, A C Testa
{"title":"Reply.","authors":"F Moro, M Vagni, H E Tran, L Boldrini, A Fagotti, A C Testa","doi":"10.1002/uog.29254","DOIUrl":"10.1002/uog.29254","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"806-807"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative ultrasound in minimally invasive surgery for deep endometriosis: time for new approaches. 术中超声在微创手术治疗深部子宫内膜异位症中的应用:新方法的时机。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-03-22 DOI: 10.1002/uog.29212
M P Nigdelis, G Hudelist, J Keckstein, E-F Solomayer, A Daniilidis, H Krentel, A-S Constantin
{"title":"Intraoperative ultrasound in minimally invasive surgery for deep endometriosis: time for new approaches.","authors":"M P Nigdelis, G Hudelist, J Keckstein, E-F Solomayer, A Daniilidis, H Krentel, A-S Constantin","doi":"10.1002/uog.29212","DOIUrl":"10.1002/uog.29212","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"676-681"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudocleft lip: is prenatal diagnosis possible? 假性唇裂:产前诊断可行吗?
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-05-08 DOI: 10.1002/uog.29249
B Melis, G Chambon, B Deloison, N Fries, L J Salomon, E Quarello
{"title":"Pseudocleft lip: is prenatal diagnosis possible?","authors":"B Melis, G Chambon, B Deloison, N Fries, L J Salomon, E Quarello","doi":"10.1002/uog.29249","DOIUrl":"10.1002/uog.29249","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"800-803"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photorealistic rendering of fetal faces from raw magnetic resonance imaging data. 来自原始磁共振成像数据的逼真的胎儿面部渲染。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-01-18 DOI: 10.1002/uog.29165
T Blanc, C Godard, D Grevent, M El Beheiry, L J Salomon, B Hajj, J-B Masson
{"title":"Photorealistic rendering of fetal faces from raw magnetic resonance imaging data.","authors":"T Blanc, C Godard, D Grevent, M El Beheiry, L J Salomon, B Hajj, J-B Masson","doi":"10.1002/uog.29165","DOIUrl":"10.1002/uog.29165","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"808-811"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Variability in antenatal prognostication of congenital diaphragmatic hernia by magnetic resonance imaging across the North American Fetal Therapy Network (NAFTNet). 北美胎儿治疗网络(NAFTNet)磁共振成像对先天性膈疝产前预测的差异性。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2025-06-01 Epub Date: 2025-05-08 DOI: 10.1002/uog.29233
N Abbasi, D Kajal, A Johnson, G Ryan, M Sanz-Cortes, S Lee, P S Shah, E E Perrone
<p><strong>Objective: </strong>To evaluate the variability in magnetic resonance imaging (MRI)-based parameters used for fetal lung volume estimation in the prediction of pulmonary hypoplasia and the degree of liver herniation in cases of antenatally diagnosed left congenital diaphragmatic hernia (CDH) across North American Fetal Therapy Network (NAFTNet) centers.</p><p><strong>Methods: </strong>In this study, 14 NAFTNet radiologists reviewed MRI exams of 15 cases of left CDH of variable severity, eight of which had liver herniation confirmed at surgery. Images were obtained at a median gestational age of 29.3 (range, 25.0-37.6) weeks, between 2020 and 2022. All participants were asked to rate image quality using a scale of 1-4 (where 1 represents excellent quality and 4 represents poor quality (unable to perform measurements)) and to determine the observed-to-expected total fetal lung volume (o/e-TFLV) using the formulae of Rypens et al. and Meyers et al., the percent predicted lung volume (PPLV), the presence or absence of liver herniation and the percentage of liver herniation (%LH). Fleiss' κ was used to assess inter-rater agreement for image-quality ratings. Concordance between participants was evaluated by determining a coefficient of variation (CV), with CV < 30 defined as acceptable. Additionally, the variation of individual participant's assessment of a case from the group average was also assessed. Data were also evaluated by center case volume, for which high volume was indicated by ≥ 15 CDH cases/year and low volume was indicated by < 15 CDH cases/year managed prenatally.</p><p><strong>Results: </strong>Overall, there was acceptable concordance for o/e-TFLV among reviewers using the formula of either Rypens et al. or Meyers et al. (median CV, 24 (interquartile range (IQR), 19-34)). Slightly lower but acceptable concordance was noted for PPLV (median CV, 26 (IQR, 18-42)). For the determination of liver herniation, most participants agreed with the final diagnosis at surgery in 14/15 cases; however, concordance was lowest among reviewers for the quantification of %LH (median CV, 46 (IQR, 44-53)). Among the three MRI exams rated as being of poor quality by the majority of participants, CV was higher for o/e-TFLV (median CV, 39) and PPLV (median CV, 43), indicating poor concordance among reviewers. No significant difference was noted in concordance among reviewers for the assessment of lung volume and liver herniation based on a center's CDH volume.</p><p><strong>Conclusion: </strong>Noticeable variability with acceptable agreement was noted for o/e-TFLV, PPLV and determination of liver herniation between NAFTNet radiologists from 14 centers in cases of left CDH. However, significant heterogeneity was noted for %LH. Concordance among reviewers was similar, irrespective of center case volume, highlighting the need for standardization of imaging protocols and CDH prognostication by MRI. © 2025 The Author(s). Ultrasound in Obstetrics & Gynec
目的:评估北美胎儿治疗网络(NAFTNet)中心胎儿肺容量评估中用于预测左先天性膈疝(CDH)病例肺发育不全和肝疝程度的磁共振成像(MRI)参数的变异性。方法:在本研究中,14名NAFTNet放射科医生回顾了15例不同严重程度的左侧CDH的MRI检查,其中8例经手术证实为肝疝。在2020年至2022年期间,中位胎龄29.3周(范围25.0-37.6)时获得图像。所有参与者被要求使用1-4的等级对图像质量进行评分(其中1代表质量好,4代表质量差(无法进行测量)),并使用Rypens等人的公式确定观察到的胎儿肺总容积(o/e-TFLV)。Meyers等人。,预测肺体积百分比(PPLV),是否存在肝疝和肝疝百分比(%LH)。使用Fleiss' κ来评估图像质量评分的评分者之间的一致性。通过确定变异系数(CV)来评估参与者之间的一致性,CV结果:总体而言,使用Rypens等人的公式,评论者之间的o/e-TFLV具有可接受的一致性。或者Meyers等人。(中位数CV, 24(四分位数间距,19-34))。PPLV的一致性稍低,但可以接受(中位CV为26 (IQR, 18-42))。对于肝疝的判断,14/15例患者同意手术后的最终诊断;然而,对于%LH的量化,研究者的一致性最低(中位CV为46 (IQR, 44-53))。在被大多数参与者评为质量较差的三项MRI检查中,o/e-TFLV(中位CV为39)和PPLV(中位CV为43)的CV较高,表明审稿人之间的一致性较差。在基于中心CDH容量评估肺容量和肝疝的一致性方面,评论者之间没有显著差异。结论:来自14个中心的NAFTNet放射科医生在左CDH病例中,o/e-TFLV、PPLV和肝疝的测定存在显著差异,但一致性可接受。然而,在%LH上发现了显著的异质性。无论中心病例的数量如何,评论者之间的一致性是相似的,这突出了成像方案和CDH MRI预测标准化的必要性。©2025作者。妇产科学超声由John Wiley & Sons Ltd代表国际妇产科学超声学会出版。
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引用次数: 0
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Ultrasound in Obstetrics & Gynecology
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