首页 > 最新文献

Ultrasound in Obstetrics & Gynecology最新文献

英文 中文
Growth velocity of fetal sacrococcygeal teratoma as predictor of perinatal morbidity and mortality: multicenter study. 预测围产期发病率和死亡率的胎儿骶尾部畸胎瘤生长速度:多中心研究。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-11-01 DOI: 10.1002/uog.29110
N Vinit, A Benachi, J Rosenblatt, J-M Jouannic, V Rousseau, A Bonnard, S Irtan, V Fouquet, Y Ville, N Khen-Dunlop, A Lapillonne, J-P Jais, S Beaudoin, L J Salomon, S Sarnacki

Objective: To identify prenatal predictors of poor perinatal outcome in fetuses with isolated sacrococcygeal teratoma (SCT).

Methods: This was a retrospective study of fetuses with isolated (non-syndromic) SCT managed at one of five pediatric surgery and/or fetal medicine centers between January 2007 and December 2017. The primary outcome was the occurrence of poor perinatal outcome, defined as prenatal death (including termination), or neonatal death or severe compromise (hemorrhagic shock). Data regarding prenatal diagnosis (sonographic features both at referral and at the last ultrasound examination before pregnancy outcome, assessment of SCT growth velocity), perinatal complications and outcome, and neonatal course were analyzed to determine prenatal SCT characteristics associated with adverse perinatal outcome.

Results: Fifty-five fetuses were included, diagnosed with isolated SCT at a median gestational age of 22 (interquartile range, 18-23) weeks. There was a poor perinatal outcome in 31% (n = 17) of these cases, including intrauterine fetal demise (4%, n = 2), pregnancy termination (13%, n = 7) and neonatal severe compromise (15%, n = 8), leading to neonatal death in five cases. The overall survival rate after prenatal diagnosis of isolated SCT was 75% (n = 41 of 55). Earlier gestational age at diagnosis (P = 0.02), large tumor volume at referral (P < 0.001), presence of one or more hemodynamic complications (P = 0.02), fast tumor growth velocity (P < 0.001) and high tumor grade (highest tumor grade ≥ 3) (P = 0.049) were associated with poor perinatal outcome on univariate analysis. On stepwise logistic regression analysis, tumor growth velocity was the only remaining independent factor associated with poor perinatal outcome (odds ratio (OR) (per 1-mm/week increase), 1.48 (95% CI, 1.22-1.97), P = 0.001). The best predictive cut-off of tumor growth velocity for poor perinatal outcome was 7 mm/week (OR, 25.7 (95% CI, 5.6-191.3), P < 0.001), yielding a sensitivity of 88% and a specificity of 77%.

Conclusions: Approximately 30% of fetuses with a diagnosis of isolated SCT have poor perinatal outcome. Tumor growth velocity ≥ 7 mm/week appears to be an appropriate discriminative cut-off for poor perinatal outcome. These results could help to inform prenatal management and counseling of parents with an affected pregnancy. © 2024 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

摘要确定孤立性骶尾部畸胎瘤(SCT)胎儿围产期不良预后的产前预测因素:这是一项回顾性研究,研究对象是2007年1月至2017年12月期间在五家小儿外科和/或胎儿医学中心之一接受治疗的孤立性(非综合征)SCT胎儿。主要结果是围产期不良结局的发生,即产前死亡(包括终止妊娠)、新生儿死亡或严重损害(失血性休克)。研究人员分析了产前诊断数据(转诊时和妊娠结局前最后一次超声检查时的声像图特征、SCT生长速度评估)、围产期并发症和结局以及新生儿病程,以确定与围产期不良结局相关的产前SCT特征:结果:共纳入 55 例胎儿,诊断为孤立性 SCT,中位胎龄为 22 周(四分位间范围为 18-23 周)。在这些病例中,31%(17 例)的围产期结局不佳,包括胎儿宫内死亡(4%,2 例)、妊娠终止(13%,7 例)和新生儿严重受损(15%,8 例),其中 5 例导致新生儿死亡。产前诊断为孤立性 SCT 的总存活率为 75%(55 例中有 41 例)。诊断时胎龄较早(P = 0.02),转诊时肿瘤体积较大(P 结论:P = 0.02):约 30% 诊断为孤立性 SCT 的胎儿围产期结局不佳。肿瘤生长速度≥ 7 mm/周似乎是围产期不良结局的一个合适的判别临界值。这些结果有助于为受影响妊娠的父母提供产前管理和咨询服务。© 2024 作者姓名妇产科超声》由 John Wiley & Sons Ltd 代表国际妇产科超声学会出版。
{"title":"Growth velocity of fetal sacrococcygeal teratoma as predictor of perinatal morbidity and mortality: multicenter study.","authors":"N Vinit, A Benachi, J Rosenblatt, J-M Jouannic, V Rousseau, A Bonnard, S Irtan, V Fouquet, Y Ville, N Khen-Dunlop, A Lapillonne, J-P Jais, S Beaudoin, L J Salomon, S Sarnacki","doi":"10.1002/uog.29110","DOIUrl":"10.1002/uog.29110","url":null,"abstract":"<p><strong>Objective: </strong>To identify prenatal predictors of poor perinatal outcome in fetuses with isolated sacrococcygeal teratoma (SCT).</p><p><strong>Methods: </strong>This was a retrospective study of fetuses with isolated (non-syndromic) SCT managed at one of five pediatric surgery and/or fetal medicine centers between January 2007 and December 2017. The primary outcome was the occurrence of poor perinatal outcome, defined as prenatal death (including termination), or neonatal death or severe compromise (hemorrhagic shock). Data regarding prenatal diagnosis (sonographic features both at referral and at the last ultrasound examination before pregnancy outcome, assessment of SCT growth velocity), perinatal complications and outcome, and neonatal course were analyzed to determine prenatal SCT characteristics associated with adverse perinatal outcome.</p><p><strong>Results: </strong>Fifty-five fetuses were included, diagnosed with isolated SCT at a median gestational age of 22 (interquartile range, 18-23) weeks. There was a poor perinatal outcome in 31% (n = 17) of these cases, including intrauterine fetal demise (4%, n = 2), pregnancy termination (13%, n = 7) and neonatal severe compromise (15%, n = 8), leading to neonatal death in five cases. The overall survival rate after prenatal diagnosis of isolated SCT was 75% (n = 41 of 55). Earlier gestational age at diagnosis (P = 0.02), large tumor volume at referral (P < 0.001), presence of one or more hemodynamic complications (P = 0.02), fast tumor growth velocity (P < 0.001) and high tumor grade (highest tumor grade ≥ 3) (P = 0.049) were associated with poor perinatal outcome on univariate analysis. On stepwise logistic regression analysis, tumor growth velocity was the only remaining independent factor associated with poor perinatal outcome (odds ratio (OR) (per 1-mm/week increase), 1.48 (95% CI, 1.22-1.97), P = 0.001). The best predictive cut-off of tumor growth velocity for poor perinatal outcome was 7 mm/week (OR, 25.7 (95% CI, 5.6-191.3), P < 0.001), yielding a sensitivity of 88% and a specificity of 77%.</p><p><strong>Conclusions: </strong>Approximately 30% of fetuses with a diagnosis of isolated SCT have poor perinatal outcome. Tumor growth velocity ≥ 7 mm/week appears to be an appropriate discriminative cut-off for poor perinatal outcome. These results could help to inform prenatal management and counseling of parents with an affected pregnancy. © 2024 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</p>","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":"64 5","pages":"651-660"},"PeriodicalIF":6.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and ultrasound features of uterine perivascular epithelioid cell tumors: case series and literature review. 子宫血管周围上皮样细胞瘤的临床和超声特征:病例系列和文献综述。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-11-01 Epub Date: 2024-10-12 DOI: 10.1002/uog.29116
R Wang, H Luo, W Cao
<p><strong>Objective: </strong>To describe the clinical and ultrasonographic features of uterine perivascular epithelioid cell tumor (PEComa) using standardized terminology.</p><p><strong>Methods: </strong>This was a retrospective analysis of patients with uterine PEComa diagnosed and confirmed by pathology and immunohistochemistry at West China Second University Hospital, Sichuan University, Sichuan, China, between January 2010 and September 2023. The Morphological Uterus Sonographic Assessment (MUSA) consensus and the International Endometrial Tumor Analysis (IETA) consensus were utilized for the standardized description of the sonographic characteristics of uterine PEComa. We summarized the clinical and ultrasound features of uterine PEComa in cases from our center and those found in a review of the literature conducted using PubMed from 1 January 2013 to 30 September 2023 (inclusive).</p><p><strong>Results: </strong>Five patients, aged 33-57 (median, 52) years, with a total of six uterine PEComa lesions were included in our cohort. All cases had complete ultrasonographic and pathological images. None of the patients had a history of tuberous sclerosis complex. Two patients had malignant PEComa (one patient had two lesions) and three had benign PEComa, originating from the cervix, myometrium or uterine cavity. Patients presented with symptoms including increased vaginal discharge, vaginal bleeding and pelvic or abdominal pain. The three patients with benign PEComa underwent total hysterectomy and bilateral adnexectomy, tumor excision and conservative management, respectively, while both malignant cases underwent total hysterectomy and bilateral adnexectomy followed by chemotherapy. Regular follow-up (from 6 to 24 months) revealed recurrence in one case. Two lesions were misdiagnosed as uterine fibroids, two as cervical cancer, one as metastatic cervical cancer (with myometrial invasion) and one was indeterminate. Ultrasound examination showed that most lesions displayed regular round or ovoid shape (66.7%), uniform echoes (66.7%) and hypoechogenicity (66.7%), with one (16.7%) malignant PEComa showing cystic areas and one (16.7%) benign PEComa showing punctate calcifications. All lesions lacked shadowing and the majority showed moderate to abundant vascularity (color score of 3-4, 83.3%). The color score was 2-4 in the periphery in 100% of cases and internally in 83.3% of cases. The three benign PEComas showed similar characteristics in vascular distribution, with scattered internal vessels and peripheral vessels exhibiting a circular pattern. The literature search identified 11 articles describing the ultrasonographic appearance of 18 cases of uterine PEComa, with similar characteristics to those in our cohort.</p><p><strong>Conclusions: </strong>The sonographic features of uterine PEComa include a uniform or non-uniform hypoechogenic mass, typically round or ovoid with regular margins, occasionally containing cystic areas or calcifications, l
目的:使用标准化术语描述子宫血管周围上皮样细胞瘤(PEComa)的临床和超声特征:使用标准化术语描述子宫血管周围上皮样细胞瘤(PEComa)的临床和超声特征:这是对2010年1月至2023年9月期间在中国四川大学华西第二医院经病理和免疫组化确诊的子宫PEComa患者的回顾性分析。采用形态学子宫声像图评估(MUSA)共识和国际子宫内膜肿瘤分析(IETA)共识对子宫PEComa的声像图特征进行标准化描述。我们总结了本中心病例以及2013年1月1日至2023年9月30日(含)期间使用PubMed进行的文献综述中发现的子宫PEComa的临床和超声特征:结果:我们的队列中有五名患者,年龄在 33-57 岁(中位数为 52 岁)之间,共有六个子宫 PEComa 病灶。所有病例均有完整的超声和病理图像。所有患者均无结节性硬化综合征病史。其中两名患者为恶性 PEComa(一名患者有两个病灶),三名患者为良性 PEComa,病灶来自宫颈、子宫肌层或子宫腔。患者出现的症状包括阴道分泌物增多、阴道出血、盆腔或腹部疼痛。三例良性 PEComa 患者分别接受了全子宫切除术和双侧附件切除术、肿瘤切除术和保守治疗,而两例恶性 PEComa 患者均接受了全子宫切除术和双侧附件切除术,随后接受了化疗。定期随访(6 至 24 个月)发现一例复发。两例病变被误诊为子宫肌瘤,两例被误诊为宫颈癌,一例被误诊为转移性宫颈癌(伴有子宫肌层浸润),还有一例诊断不明确。超声检查显示,大多数病变呈规则的圆形或卵圆形(66.7%),回声均匀(66.7%),低回声(66.7%),其中一个(16.7%)恶性宫颈息肉瘤呈囊性区域,一个(16.7%)良性宫颈息肉瘤呈点状钙化。所有病变均无阴影,大多数病变显示中等至丰富的血管(颜色评分为 3-4,占 83.3%)。在 100%的病例中,病变周边的颜色评分为 2-4,而在 83.3%的病例中,病变内部的颜色评分为 2-4。这三种良性 PEC 瘤的血管分布特征相似,内部血管散在分布,周边血管呈环状分布。文献检索发现了11篇文章,描述了18例子宫PEC瘤的超声波外观,其特征与我们队列中的病例相似:结论:子宫内膜异位瘤的声像图特征包括均匀或不均匀的低水肿性肿块,一般为圆形或卵圆形,边缘规则,偶见囊性区域或钙化,缺乏阴影,通常显示中等至丰富的血管。虽然子宫长纤维瘤的术前超声诊断仍具有挑战性,特别是考虑到此处描述的声像图特征的非特异性,但分散的瘤内血管和外周环形血管分布可作为子宫长纤维瘤的诊断线索,但需要更多病例来证实。© 2024 国际妇产科超声学会。
{"title":"Clinical and ultrasound features of uterine perivascular epithelioid cell tumors: case series and literature review.","authors":"R Wang, H Luo, W Cao","doi":"10.1002/uog.29116","DOIUrl":"10.1002/uog.29116","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To describe the clinical and ultrasonographic features of uterine perivascular epithelioid cell tumor (PEComa) using standardized terminology.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This was a retrospective analysis of patients with uterine PEComa diagnosed and confirmed by pathology and immunohistochemistry at West China Second University Hospital, Sichuan University, Sichuan, China, between January 2010 and September 2023. The Morphological Uterus Sonographic Assessment (MUSA) consensus and the International Endometrial Tumor Analysis (IETA) consensus were utilized for the standardized description of the sonographic characteristics of uterine PEComa. We summarized the clinical and ultrasound features of uterine PEComa in cases from our center and those found in a review of the literature conducted using PubMed from 1 January 2013 to 30 September 2023 (inclusive).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Five patients, aged 33-57 (median, 52) years, with a total of six uterine PEComa lesions were included in our cohort. All cases had complete ultrasonographic and pathological images. None of the patients had a history of tuberous sclerosis complex. Two patients had malignant PEComa (one patient had two lesions) and three had benign PEComa, originating from the cervix, myometrium or uterine cavity. Patients presented with symptoms including increased vaginal discharge, vaginal bleeding and pelvic or abdominal pain. The three patients with benign PEComa underwent total hysterectomy and bilateral adnexectomy, tumor excision and conservative management, respectively, while both malignant cases underwent total hysterectomy and bilateral adnexectomy followed by chemotherapy. Regular follow-up (from 6 to 24 months) revealed recurrence in one case. Two lesions were misdiagnosed as uterine fibroids, two as cervical cancer, one as metastatic cervical cancer (with myometrial invasion) and one was indeterminate. Ultrasound examination showed that most lesions displayed regular round or ovoid shape (66.7%), uniform echoes (66.7%) and hypoechogenicity (66.7%), with one (16.7%) malignant PEComa showing cystic areas and one (16.7%) benign PEComa showing punctate calcifications. All lesions lacked shadowing and the majority showed moderate to abundant vascularity (color score of 3-4, 83.3%). The color score was 2-4 in the periphery in 100% of cases and internally in 83.3% of cases. The three benign PEComas showed similar characteristics in vascular distribution, with scattered internal vessels and peripheral vessels exhibiting a circular pattern. The literature search identified 11 articles describing the ultrasonographic appearance of 18 cases of uterine PEComa, with similar characteristics to those in our cohort.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The sonographic features of uterine PEComa include a uniform or non-uniform hypoechogenic mass, typically round or ovoid with regular margins, occasionally containing cystic areas or calcifications, l","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"687-695"},"PeriodicalIF":6.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of fetal cardiac function in pregnant women with anemia: prospective case-control study. 贫血孕妇胎儿心脏功能评估:前瞻性病例对照研究。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-11-01 Epub Date: 2024-10-15 DOI: 10.1002/uog.27637
Z Agaoglu, A Tanacan, U Gurbuz, M Ozturk Agaoglu, M Haksever, G Okutucu, O Kara, D Sahin
<p><strong>Objective: </strong>To compare fetal cardiac function in pregnant women with iron deficiency anemia (IDA) vs healthy pregnant controls.</p><p><strong>Methods: </strong>This was a single-center, prospective, case-control study conducted in a tertiary hospital between November 2022 and September 2023. Women diagnosed with IDA who attended as outpatients at the pregnancy follow-up clinic at 30-34 weeks' gestation or who were hospitalized for intravenous iron treatment owing to profound anemia were included. The control group consisted of randomly selected gestational-age-matched pregnant women with no obstetric complications or comorbidities and who did not have anemia. Patients underwent two-dimensional imaging, followed by pulsed-wave Doppler and M-mode and tissue Doppler imaging (TDI) to evaluate fetal cardiac function. A fetal cardiac score was calculated using systolic, diastolic and global hemodynamic function parameters, and was compared between patients with IDA and those without. The fetal cardiac score was also assessed according to the severity of anemia in the IDA group.</p><p><strong>Results: </strong>A total of 150 patients, comprising 50 patients with IDA and 100 healthy pregnant women at 30-34 weeks' gestation, were included in the study. Of the patients with IDA, 20 had mild, 18 had moderate and 12 had severe anemia. The fetal myocardial performance index and isovolumetric relaxation time were significantly higher in the IDA group compared with the control group (P < 0.0001 for both), while isovolumetric contraction time was similar. Among the fetal tricuspid and mitral valve diastolic parameters, the E, A and E/A values were significantly lower in the IDA group (P < 0.05 for all). Mitral (MAPSE) and tricuspid (TAPSE) annular plane systolic excursions were significantly lower in the IDA group (P < 0.05 for both). The IDA group also had significantly lower values for the TDI parameters mitral and tricuspid E', A', S' and E'/A' ratio and a significantly higher E/E' ratio (P < 0.05 for all). Among the IDA subgroups, a significant decrease was observed in the tricuspid and mitral A, E and E/A ratio in fetuses whose mothers had severe anemia (P = 0.001). M-mode Doppler analysis revealed significantly lower fetal TAPSE and MAPSE in the patient group with severe maternal anemia (P = 0.001 for both). According to the subgroup comparison of TDI findings, the fetuses of mothers with severe anemia had significantly lower tricuspid and mitral E', A', S' and E'/A' ratio values and a significantly higher E/E' ratio (P < 0.05 for all). The fetal cardiac score was significantly higher in the maternal IDA group compared with the control group (P < 0.001). A significant negative correlation was found between maternal hemoglobin level and fetal cardiac score (P < 0.001).</p><p><strong>Conclusions: </strong>We observed differences in fetal systolic and diastolic cardiac function in pregnancies with maternal IDA. Fetal cardiac function was af
目的:比较缺铁性贫血(IDA)孕妇和健康对照组胎儿的心脏功能:比较缺铁性贫血(IDA)孕妇和健康对照组胎儿的心脏功能:这项单中心、前瞻性、病例对照研究在一家三级医院进行。研究共纳入 150 名患者,包括 50 名缺铁性贫血患者和 100 名妊娠 30-34 周的健康孕妇。在贫血患者中,20 人患有轻度贫血,18 人患有中度贫血,12 人患有重度贫血。对胎儿心脏功能进行了脉冲波多普勒、M-模式和组织多普勒成像(TDI)评估。根据收缩、舒张和整体血液动力学功能参数计算胎儿心脏评分:结果:IDA组的心肌功能指数和等容舒张时间明显高于对照组,而等容收缩时间与对照组相似。在三尖瓣和二尖瓣舒张参数中,IDA 组的 E 值、A 值和 E/A 值明显低于对照组(p 结论:三尖瓣和二尖瓣舒张参数可能存在变化:IDA孕妇胎儿的心脏收缩和舒张功能可能会发生变化。本研究显示,IDA 孕妇的胎儿 E/E' 比值升高,表明胎儿心脏成熟度降低。在IDA组中,严重贫血孕妇的胎儿心脏功能受到的影响更大。本文受版权保护。保留所有权利。
{"title":"Assessment of fetal cardiac function in pregnant women with anemia: prospective case-control study.","authors":"Z Agaoglu, A Tanacan, U Gurbuz, M Ozturk Agaoglu, M Haksever, G Okutucu, O Kara, D Sahin","doi":"10.1002/uog.27637","DOIUrl":"10.1002/uog.27637","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To compare fetal cardiac function in pregnant women with iron deficiency anemia (IDA) vs healthy pregnant controls.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This was a single-center, prospective, case-control study conducted in a tertiary hospital between November 2022 and September 2023. Women diagnosed with IDA who attended as outpatients at the pregnancy follow-up clinic at 30-34 weeks' gestation or who were hospitalized for intravenous iron treatment owing to profound anemia were included. The control group consisted of randomly selected gestational-age-matched pregnant women with no obstetric complications or comorbidities and who did not have anemia. Patients underwent two-dimensional imaging, followed by pulsed-wave Doppler and M-mode and tissue Doppler imaging (TDI) to evaluate fetal cardiac function. A fetal cardiac score was calculated using systolic, diastolic and global hemodynamic function parameters, and was compared between patients with IDA and those without. The fetal cardiac score was also assessed according to the severity of anemia in the IDA group.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 150 patients, comprising 50 patients with IDA and 100 healthy pregnant women at 30-34 weeks' gestation, were included in the study. Of the patients with IDA, 20 had mild, 18 had moderate and 12 had severe anemia. The fetal myocardial performance index and isovolumetric relaxation time were significantly higher in the IDA group compared with the control group (P &lt; 0.0001 for both), while isovolumetric contraction time was similar. Among the fetal tricuspid and mitral valve diastolic parameters, the E, A and E/A values were significantly lower in the IDA group (P &lt; 0.05 for all). Mitral (MAPSE) and tricuspid (TAPSE) annular plane systolic excursions were significantly lower in the IDA group (P &lt; 0.05 for both). The IDA group also had significantly lower values for the TDI parameters mitral and tricuspid E', A', S' and E'/A' ratio and a significantly higher E/E' ratio (P &lt; 0.05 for all). Among the IDA subgroups, a significant decrease was observed in the tricuspid and mitral A, E and E/A ratio in fetuses whose mothers had severe anemia (P = 0.001). M-mode Doppler analysis revealed significantly lower fetal TAPSE and MAPSE in the patient group with severe maternal anemia (P = 0.001 for both). According to the subgroup comparison of TDI findings, the fetuses of mothers with severe anemia had significantly lower tricuspid and mitral E', A', S' and E'/A' ratio values and a significantly higher E/E' ratio (P &lt; 0.05 for all). The fetal cardiac score was significantly higher in the maternal IDA group compared with the control group (P &lt; 0.001). A significant negative correlation was found between maternal hemoglobin level and fetal cardiac score (P &lt; 0.001).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;We observed differences in fetal systolic and diastolic cardiac function in pregnancies with maternal IDA. Fetal cardiac function was af","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"604-612"},"PeriodicalIF":6.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal propranolol treatment for fetal pleural effusion. 母体普萘洛尔治疗胎儿胸腔积液。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-11-01 DOI: 10.1002/uog.27639
C A Cluver, R Alexander, L Pistorius
{"title":"Maternal propranolol treatment for fetal pleural effusion.","authors":"C A Cluver, R Alexander, L Pistorius","doi":"10.1002/uog.27639","DOIUrl":"10.1002/uog.27639","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":"703-704"},"PeriodicalIF":6.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posterior complex: clue for suspicion of partial agenesis of corpus callosum at fetal brain screening. 后复合体:胎儿脑筛查中怀疑胼胝体部分缺失的线索。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-10-30 DOI: 10.1002/uog.29136
F Viñals, F Correa
{"title":"Posterior complex: clue for suspicion of partial agenesis of corpus callosum at fetal brain screening.","authors":"F Viñals, F Correa","doi":"10.1002/uog.29136","DOIUrl":"https://doi.org/10.1002/uog.29136","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of Fetal Medicine Foundation charts for fetal growth in twins: nationwide Danish cohort study. 胎儿医学基金会图表对双胞胎胎儿发育的验证:丹麦全国性队列研究。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-10-27 DOI: 10.1002/uog.29125
S E Kristensen, A Wright, D Wright, K Gadsbøll, C K Ekelund, P Sandager, F S Jørgensen, E Hoseth, L Sperling, H J Zingenberg, K Sundberg, A McLennan, K H Nicolaides, O B Petersen

Objective: To assess the validity of the Fetal Medicine Foundation (FMF) chorionicity-specific models for fetal growth in twin pregnancy.

Methods: This was an external validation study of the FMF models using a nationwide Danish cohort of twin pregnancies. The cohort included all dichorionic (DC) and monochorionic diamniotic (MCDA) twin pregnancies with an estimated delivery date between 2008 and 2018, which satisfied the following inclusion criteria: two live fetuses at the first-trimester ultrasound scan (11-14 weeks' gestation); biometric measurements available for the calculation of estimated fetal weight (EFW) using the Hadlock-3 formula; and delivery of two liveborn infants. Validation involved assessing the distributional properties of the models and estimating the mean EFW Z-score deviations. Additionally, the models were applied to pregnancies that delivered preterm and attended non-scheduled visits (complicated pregnancies).

Results: Overall, 8542 DC and 1675 MCDA twin pregnancies met the inclusion criteria. In DC twins, 17 084 fetuses were evaluated at a total of 95 346 ultrasound scans, of which 44.5% were performed at scheduled visits in pregnancies carried to 37 + 0 weeks or later. The median number of growth scans per DC twin fetus from 20 + 0 weeks onwards was four. The model showed good agreement with the validation cohort for scheduled visits in DC twins delivered at 37 + 0 weeks or later (mean EFW Z-score, -0.14 ± 1.05). In MCDA twins, 3350 fetuses underwent 31 632 eligible ultrasound scans, of which 59.5% were performed at scheduled visits in pregnancies carried to 36 + 0 weeks or later. The median number of growth scans per MCDA twin fetus from 16 + 0 weeks onwards was 10. The model showed favorable agreement with the validation cohort for scheduled visits in MCDA twins delivered at 36 + 0 weeks or later (mean EFW Z-score, -0.09 ± 1.01). Non-scheduled visits and preterm delivery before 37 + 0 weeks for DC twins and before 36 + 0 weeks for MCDA twins corresponded with smaller weight estimates, which was consistent with the study's definition of complicated pregnancy.

Conclusions: The FMF models provide a good fit for EFW measurements in our Danish national cohort of uncomplicated twin pregnancies assessed at routine scans. Therefore, the FMF models establish robust criteria for subsequent investigations and potential clinical applications. Future research should focus on exploring the consequences of clinical implementation, particularly regarding the identification of twins that are small-for-gestational age, as they are especially susceptible to adverse perinatal outcome. © 2024 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

目的评估胎儿医学基金会(FMF)绒毛膜特异性模型对双胎妊娠胎儿生长的有效性:这是一项利用丹麦全国双胎妊娠队列对 FMF 模型进行的外部验证研究。该队列包括所有预产期在2008年至2018年之间的双绒毛膜双胎(DC)和单绒毛膜双胎(MCDA)妊娠,这些妊娠符合以下纳入标准:在第一孕期超声扫描(孕11-14周)时有两个活胎儿;生物测量数据可用于使用Hadlock-3公式计算估计胎儿体重(EFW);并有两个活产婴儿出生。验证包括评估模型的分布特性和估计平均 EFW Z 分数偏差。此外,这些模型还适用于早产和未按计划就诊的孕妇(复杂妊娠):共有 8542 例 DC 双胎和 1675 例 MCDA 双胎符合纳入标准。在直肠双胎中,17 084 名胎儿共接受了 95 346 次超声波扫描,其中 44.5%是在妊娠 37+0 周或更晚的孕妇接受定期检查时进行的。从 20+0 周起,每个 DC 双胎的生长扫描次数中位数为 4 次。该模型与验证队列中在37+0周或更晚分娩的直肠畸形双胞胎中进行的定期检查结果显示出良好的一致性(平均EFW Z-score,-0.14 ± 1.05)。在 MCDA 双胎中,有 3350 个胎儿接受了 31 632 次符合条件的超声扫描,其中 59.5%是在妊娠 36+0 周或更晚时进行的计划访视中进行的。从 16+0 周起,每个 MCDA 双胎的生长扫描次数中位数为 10 次。该模型与验证队列对 36+0 周或更晚分娩的 MCDA 双胎的计划访视显示出良好的一致性(平均 EFW Z-score,-0.09 ± 1.01)。非计划访视和早产(DC 双胞胎在 37+0 周之前、MCDA 双胞胎在 36+0 周之前)与较小的体重估计值相对应,这与该研究对复杂妊娠的定义一致:FMF模型很好地拟合了常规扫描评估的丹麦全国无并发症双胞胎队列中的EFW测量值。因此,FMF 模型为后续研究和潜在的临床应用建立了可靠的标准。未来的研究应侧重于探索临床应用的后果,特别是在识别小于胎龄的双胞胎方面,因为这些双胞胎特别容易出现不良围产期结局。© 2024 作者姓名妇产科超声》由 John Wiley & Sons Ltd 代表国际妇产科超声学会出版。
{"title":"Validation of Fetal Medicine Foundation charts for fetal growth in twins: nationwide Danish cohort study.","authors":"S E Kristensen, A Wright, D Wright, K Gadsbøll, C K Ekelund, P Sandager, F S Jørgensen, E Hoseth, L Sperling, H J Zingenberg, K Sundberg, A McLennan, K H Nicolaides, O B Petersen","doi":"10.1002/uog.29125","DOIUrl":"https://doi.org/10.1002/uog.29125","url":null,"abstract":"<p><strong>Objective: </strong>To assess the validity of the Fetal Medicine Foundation (FMF) chorionicity-specific models for fetal growth in twin pregnancy.</p><p><strong>Methods: </strong>This was an external validation study of the FMF models using a nationwide Danish cohort of twin pregnancies. The cohort included all dichorionic (DC) and monochorionic diamniotic (MCDA) twin pregnancies with an estimated delivery date between 2008 and 2018, which satisfied the following inclusion criteria: two live fetuses at the first-trimester ultrasound scan (11-14 weeks' gestation); biometric measurements available for the calculation of estimated fetal weight (EFW) using the Hadlock-3 formula; and delivery of two liveborn infants. Validation involved assessing the distributional properties of the models and estimating the mean EFW Z-score deviations. Additionally, the models were applied to pregnancies that delivered preterm and attended non-scheduled visits (complicated pregnancies).</p><p><strong>Results: </strong>Overall, 8542 DC and 1675 MCDA twin pregnancies met the inclusion criteria. In DC twins, 17 084 fetuses were evaluated at a total of 95 346 ultrasound scans, of which 44.5% were performed at scheduled visits in pregnancies carried to 37 + 0 weeks or later. The median number of growth scans per DC twin fetus from 20 + 0 weeks onwards was four. The model showed good agreement with the validation cohort for scheduled visits in DC twins delivered at 37 + 0 weeks or later (mean EFW Z-score, -0.14 ± 1.05). In MCDA twins, 3350 fetuses underwent 31 632 eligible ultrasound scans, of which 59.5% were performed at scheduled visits in pregnancies carried to 36 + 0 weeks or later. The median number of growth scans per MCDA twin fetus from 16 + 0 weeks onwards was 10. The model showed favorable agreement with the validation cohort for scheduled visits in MCDA twins delivered at 36 + 0 weeks or later (mean EFW Z-score, -0.09 ± 1.01). Non-scheduled visits and preterm delivery before 37 + 0 weeks for DC twins and before 36 + 0 weeks for MCDA twins corresponded with smaller weight estimates, which was consistent with the study's definition of complicated pregnancy.</p><p><strong>Conclusions: </strong>The FMF models provide a good fit for EFW measurements in our Danish national cohort of uncomplicated twin pregnancies assessed at routine scans. Therefore, the FMF models establish robust criteria for subsequent investigations and potential clinical applications. Future research should focus on exploring the consequences of clinical implementation, particularly regarding the identification of twins that are small-for-gestational age, as they are especially susceptible to adverse perinatal outcome. © 2024 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</p>","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting neonatal mortality prior to discharge from hospital in prenatally diagnosed left congenital diaphragmatic hernia. 预测产前诊断左侧先天性膈疝患者出院前的新生儿死亡率。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-10-24 DOI: 10.1002/uog.29121
S Shinar, A Otvodenko, D Kajal, P P L Chiu, S Lee, P S Shah, T Van Mieghem, Y Kunpalin, A-M Guerguerian, G Ryan, N Abbasi

Objectives: To evaluate the association of standardized prenatal imaging parameters and immediate neonatal variables with mortality prior to discharge in infants with isolated left congenital diaphragmatic hernia (LCDH), and to compare the performance of ultrasound- and magnetic resonance imaging (MRI)-based severity grading for the prediction of neonatal mortality.

Methods: This was a retrospective study of infants with prenatally diagnosed isolated LCDH referred to a single tertiary center between 2008 and 2020. Fetuses with right or bilateral congenital diaphragmatic hernia, additional major structural anomaly or known genetic condition, as well as cases that underwent fetal intervention or declined postnatal intervention, were excluded. Ultrasound and MRI images were reviewed retrospectively. Univariable and multivariable analyses were performed, incorporating prenatal and immediate neonatal factors to analyze the association with neonatal mortality prior to discharge, and a prediction calculator was generated. The performance of ultrasound and that of MRI for the prediction of neonatal mortality were compared.

Results: Of 253 pregnancies with fetal CDH, 104 met the inclusion criteria, of whom 77 (74%) neonates survived to discharge. Seventy-five fetuses underwent both prenatal ultrasound and MRI. On multivariable analysis, observed/expected (o/e) lung-to-head ratio and o/e total fetal lung volume were associated independently with neonatal death (adjusted odds ratio, 0.89 (95% CI, 0.83-0.95) and 0.90 (95% CI, 0.84-0.97), respectively), whereas liver position was not. There was no significant difference in predictive performance between using ultrasound and MRI together (area under the receiver-operating-characteristics curve (AUC), 0.85 (95% CI, 0.76-0.93)) compared with using ultrasound alone (AUC, 0.81 (95% CI, 0.72-0.90); P = 0.19). The addition of neonatal parameters (gestational age at birth and small-for-gestational age) did not improve model performance (AUC, 0.87 (95% CI, 0.80-0.95)) compared with the combined ultrasound and MRI model (P = 0.22). There was poor agreement between severity assessment on ultrasound and MRI (Cohen's κ, 0.19). Most discrepancies were seen among cases deemed to be non-severe on ultrasound and severe on MRI, and outcomes were more consistent with MRI-based prognostication.

Conclusions: In fetuses with prenatally diagnosed isolated LCDH, mortality prediction using standardized ultrasound and MRI measurements performed reasonably well. In cases classified as non-severe on ultrasound, MRI is recommended, as it may provide more accurate prognostication and assist in the determination of candidacy for fetal intervention. © 2024 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

目的评估标准化产前成像参数和新生儿即时变量与孤立性左侧先天性膈疝(LCDH)婴儿出院前死亡率的关系,并比较基于超声和磁共振成像(MRI)的严重程度分级在预测新生儿死亡率方面的性能:这是一项回顾性研究,研究对象是2008年至2020年间转诊至一家三级医疗中心的产前诊断为孤立性LCDH的婴儿。排除了右侧或双侧先天性膈疝、其他主要结构异常或已知遗传病的胎儿,以及接受胎儿干预或拒绝产后干预的病例。对超声和核磁共振图像进行了回顾性分析。结合产前和新生儿期因素进行单变量和多变量分析,分析出院前新生儿死亡率的相关性,并生成预测计算器。比较了超声和磁共振成像在预测新生儿死亡率方面的性能:结果:在253例患有胎儿CDH的孕妇中,104例符合纳入标准,其中77例(74%)新生儿存活至出院。75名胎儿同时接受了产前超声和磁共振成像检查。在多变量分析中,观察/预期(o/e)肺头比和o/e胎儿肺总量与新生儿死亡独立相关(调整后的几率分别为0.89(95% CI,0.83-0.95)和0.90(95% CI,0.84-0.97)),而肝脏位置与新生儿死亡无关。同时使用超声波和核磁共振成像(受体运算特征曲线下面积(AUC)为 0.85(95% CI,0.76-0.93))与单独使用超声波(AUC,0.81(95% CI,0.72-0.90);P = 0.19)在预测性能上没有明显差异。与超声和磁共振成像联合模型相比,增加新生儿参数(出生时胎龄和小于胎龄)并没有提高模型性能(AUC,0.87(95% CI,0.80-0.95))(P = 0.22)。超声和核磁共振成像的严重程度评估之间的一致性较差(Cohen's κ,0.19)。大多数差异出现在超声检查认为不严重而核磁共振检查认为严重的病例中,而基于核磁共振检查的预后结果更为一致:结论:对于产前诊断为孤立性LCDH的胎儿,使用标准化超声和磁共振成像测量方法预测死亡率的效果相当好。结论:对于产前诊断为孤立性 LCDH 的胎儿,使用标准化超声和核磁共振成像测量结果预测死亡率的效果相当不错。对于超声分类为非重度的病例,建议使用核磁共振成像,因为它可以提供更准确的预后,并有助于确定胎儿是否适合接受干预。© 2024 作者姓名妇产科超声》由 John Wiley & Sons Ltd 代表国际妇产科超声学会出版。
{"title":"Predicting neonatal mortality prior to discharge from hospital in prenatally diagnosed left congenital diaphragmatic hernia.","authors":"S Shinar, A Otvodenko, D Kajal, P P L Chiu, S Lee, P S Shah, T Van Mieghem, Y Kunpalin, A-M Guerguerian, G Ryan, N Abbasi","doi":"10.1002/uog.29121","DOIUrl":"https://doi.org/10.1002/uog.29121","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the association of standardized prenatal imaging parameters and immediate neonatal variables with mortality prior to discharge in infants with isolated left congenital diaphragmatic hernia (LCDH), and to compare the performance of ultrasound- and magnetic resonance imaging (MRI)-based severity grading for the prediction of neonatal mortality.</p><p><strong>Methods: </strong>This was a retrospective study of infants with prenatally diagnosed isolated LCDH referred to a single tertiary center between 2008 and 2020. Fetuses with right or bilateral congenital diaphragmatic hernia, additional major structural anomaly or known genetic condition, as well as cases that underwent fetal intervention or declined postnatal intervention, were excluded. Ultrasound and MRI images were reviewed retrospectively. Univariable and multivariable analyses were performed, incorporating prenatal and immediate neonatal factors to analyze the association with neonatal mortality prior to discharge, and a prediction calculator was generated. The performance of ultrasound and that of MRI for the prediction of neonatal mortality were compared.</p><p><strong>Results: </strong>Of 253 pregnancies with fetal CDH, 104 met the inclusion criteria, of whom 77 (74%) neonates survived to discharge. Seventy-five fetuses underwent both prenatal ultrasound and MRI. On multivariable analysis, observed/expected (o/e) lung-to-head ratio and o/e total fetal lung volume were associated independently with neonatal death (adjusted odds ratio, 0.89 (95% CI, 0.83-0.95) and 0.90 (95% CI, 0.84-0.97), respectively), whereas liver position was not. There was no significant difference in predictive performance between using ultrasound and MRI together (area under the receiver-operating-characteristics curve (AUC), 0.85 (95% CI, 0.76-0.93)) compared with using ultrasound alone (AUC, 0.81 (95% CI, 0.72-0.90); P = 0.19). The addition of neonatal parameters (gestational age at birth and small-for-gestational age) did not improve model performance (AUC, 0.87 (95% CI, 0.80-0.95)) compared with the combined ultrasound and MRI model (P = 0.22). There was poor agreement between severity assessment on ultrasound and MRI (Cohen's κ, 0.19). Most discrepancies were seen among cases deemed to be non-severe on ultrasound and severe on MRI, and outcomes were more consistent with MRI-based prognostication.</p><p><strong>Conclusions: </strong>In fetuses with prenatally diagnosed isolated LCDH, mortality prediction using standardized ultrasound and MRI measurements performed reasonably well. In cases classified as non-severe on ultrasound, MRI is recommended, as it may provide more accurate prognostication and assist in the determination of candidacy for fetal intervention. © 2024 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</p>","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biparietal diameter vs crown-rump length as standard parameter for late first-trimester pregnancy dating. 双顶径与冠状脊长度的比较,作为第一胎晚期妊娠测定的标准参数。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-10-24 DOI: 10.1002/uog.29124
H K Gjessing, P Grøttum, J M Dreier, S H Eik-Nes

Objective: To compare the precision of biparietal diameter (BPD) and crown-rump length (CRL) as predictors of gestational age in the human fetus in the late first and early second trimesters, using a population-based approach.

Methods: We constructed term and gestational-age prediction curves for first-trimester dating, based on 11 041 pregnancies with 12 260 measurements of CRL and/or BPD from a population-based Norwegian clinical database. We used a population-based approach with local linear quantile regression, combined with a time-to-event strategy that compensates for induced births. Term prediction precision was assessed by estimating and comparing the prediction residual curves using a time-to-event analysis. Individual differences in gestational-age predictions from CRL and BPD were assessed using measurements performed on the same fetus on the same day. A sensitivity analysis was performed to evaluate the effect of not distinguishing between non-spontaneous and spontaneous births.

Results: CRL and BPD provided almost identical term prediction precision judged from the residual distribution. In about 51% of examinations, the difference in predicted gestational age was 1 day or less; 24% of examinations had a difference of 2 days, 14% had a difference of 3 days, 7% had a difference of 4 days and only 5% of all examinations had a difference of 5 days or more. Incorrectly removing induced births from the analysis, or treating them as spontaneous, would cause a substantial systematic prediction bias of about 2 days.

Conclusions: Based on population data, using comparisons at an individual level, our study found that BPD is as precise as CRL when used for first-trimester dating. BPD has advantages from a clinical point of view, since it is technically less challenging and less time-consuming to measure compared with CRL, and can be measured and assessed throughout the entire pregnancy. © 2024 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

目的比较双顶径(BPD)和冠臀长(CRL)作为人类胎儿在妊娠前三个月晚期和后三个月早期的孕龄预测指标的精确性:我们根据挪威人口临床数据库中 11 041 例妊娠和 12 260 次 CRL 和/或 BPD 测量结果,构建了第一孕期的足月和胎龄预测曲线。我们采用了基于人群的局部线性量化回归方法,并结合补偿引产的时间到事件策略。通过时间到事件分析来估计和比较预测残差曲线,从而评估了预产期预测精度。通过对同一天的同一胎儿进行测量,评估了 CRL 和 BPD 预测胎龄的个体差异。进行了一项敏感性分析,以评估不区分非自然分娩和自然分娩的影响:结果:从残差分布来看,CRL 和 BPD 提供了几乎相同的足月预测精度。在约 51% 的检查中,预测胎龄的差异为 1 天或更小;24% 的检查差异为 2 天,14% 的检查差异为 3 天,7% 的检查差异为 4 天,只有 5% 的检查差异为 5 天或更多。如果不正确地将引产从分析中剔除,或将其视为自然分娩,则会造成约 2 天的严重系统性预测偏差:我们的研究基于人口数据,通过个体水平的比较发现,BPD 与 CRL 在用于第一胎测算时同样精确。从临床角度来看,BPD 具有优势,因为与 CRL 相比,BPD 的测量技术难度更低,耗时更少,而且可以在整个孕期进行测量和评估。© 2024 作者。妇产科超声》由 John Wiley & Sons Ltd 代表国际妇产科超声学会出版。
{"title":"Biparietal diameter vs crown-rump length as standard parameter for late first-trimester pregnancy dating.","authors":"H K Gjessing, P Grøttum, J M Dreier, S H Eik-Nes","doi":"10.1002/uog.29124","DOIUrl":"https://doi.org/10.1002/uog.29124","url":null,"abstract":"<p><strong>Objective: </strong>To compare the precision of biparietal diameter (BPD) and crown-rump length (CRL) as predictors of gestational age in the human fetus in the late first and early second trimesters, using a population-based approach.</p><p><strong>Methods: </strong>We constructed term and gestational-age prediction curves for first-trimester dating, based on 11 041 pregnancies with 12 260 measurements of CRL and/or BPD from a population-based Norwegian clinical database. We used a population-based approach with local linear quantile regression, combined with a time-to-event strategy that compensates for induced births. Term prediction precision was assessed by estimating and comparing the prediction residual curves using a time-to-event analysis. Individual differences in gestational-age predictions from CRL and BPD were assessed using measurements performed on the same fetus on the same day. A sensitivity analysis was performed to evaluate the effect of not distinguishing between non-spontaneous and spontaneous births.</p><p><strong>Results: </strong>CRL and BPD provided almost identical term prediction precision judged from the residual distribution. In about 51% of examinations, the difference in predicted gestational age was 1 day or less; 24% of examinations had a difference of 2 days, 14% had a difference of 3 days, 7% had a difference of 4 days and only 5% of all examinations had a difference of 5 days or more. Incorrectly removing induced births from the analysis, or treating them as spontaneous, would cause a substantial systematic prediction bias of about 2 days.</p><p><strong>Conclusions: </strong>Based on population data, using comparisons at an individual level, our study found that BPD is as precise as CRL when used for first-trimester dating. BPD has advantages from a clinical point of view, since it is technically less challenging and less time-consuming to measure compared with CRL, and can be measured and assessed throughout the entire pregnancy. © 2024 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</p>","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Near-miss criteria for stillbirth in global research: the 'In Utero' consensus. 全球研究中的死胎近似标准:"子宫内 "共识。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-10-10 DOI: 10.1002/uog.29120
S J Gordijn, A T Papageorghiou, A L David, S Ali, W Ganzevoort
{"title":"Near-miss criteria for stillbirth in global research: the 'In Utero' consensus.","authors":"S J Gordijn, A T Papageorghiou, A L David, S Ali, W Ganzevoort","doi":"10.1002/uog.29120","DOIUrl":"https://doi.org/10.1002/uog.29120","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of interindividual follicular size variation at ovulation in natural-cycle frozen embryo transfer. 评估自然周期冷冻胚胎移植排卵时个体间卵泡大小的变化。
IF 6.1 1区 医学 Q1 ACOUSTICS Pub Date : 2024-10-10 DOI: 10.1002/uog.29123
J Edades, E Kalafat, B Ata, R Del Gallego, H Fatemi, B Lawrenz
{"title":"Assessment of interindividual follicular size variation at ovulation in natural-cycle frozen embryo transfer.","authors":"J Edades, E Kalafat, B Ata, R Del Gallego, H Fatemi, B Lawrenz","doi":"10.1002/uog.29123","DOIUrl":"https://doi.org/10.1002/uog.29123","url":null,"abstract":"","PeriodicalId":23454,"journal":{"name":"Ultrasound in Obstetrics & Gynecology","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Ultrasound in Obstetrics & Gynecology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1