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Tracheobronchial amyloidosis, isolated lung amyloidoma: invasive diagnostic and treatment 气管支气管淀粉样变性,孤立性肺淀粉样瘤:侵入性诊断和治疗
Q4 Medicine Pub Date : 2023-03-23 DOI: 10.24884/0042-4625-2023-182-1-43-49
V. P. Molodcova, A. A. Ilin, I. V. Dvorakovskaya, A. L. Akopov
The article presents the latest trends of the diagnosis and treatment of tracheobronchial amyloidosis. Constriction of the bronchus due to amyloid deposits requires immunohistochemistry for protein typing. The only way of major airways recanalization is endoscopic surgical treatment. It is described the experience of treating four patients with tracheobronchial amyloidosis, in one of whom, a rare form of amyloidosis – lung amyloidoma developed.
本文介绍了气管支气管淀粉样变性的诊断和治疗的最新进展。淀粉样蛋白沉积引起的支气管收缩需要免疫组织化学进行蛋白分型。主要气道再通的唯一途径是内镜手术治疗。本文描述了治疗4例气管支气管淀粉样变性患者的经验,其中1例发生了一种罕见的淀粉样变性-肺淀粉样瘤。
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引用次数: 0
The use of flowmetry during coronary bypass surgery in patients with diffuse coronary bed lesion 弥漫性冠状动脉床病变患者在冠状动脉搭桥手术中的应用
Q4 Medicine Pub Date : 2023-03-13 DOI: 10.24884/0042-4625-2023-182-1-11-19
G. G. Borshchev, R. V. Sidorov, D. S. Ulbashev
Introduction . In recent decades, the number of patients with coronary artery disease and diffuse coronary artery disease has significantly increased. Performing the full volume of myocardial revascularization in such patients is not always possible due to the nature of the lesion of the coronary bed, and the risk of shunt dysfunction in the early postoperative period remains high. Therefore, the use of ultrasound intraoperative flowmetry in coronary bypass surgery is especially necessary, but the issues of optimal indicators of graft patency remain unresolved. The Objective was to evaluate the possibilities of using intraoperative ultrasound flowmetry in patients with diffuse coronary bed lesion. Methods and Materials . The study included 188 patients with diffuse coronary bed lesion who underwent coronary bypass surgery at the St. George Thoracic and Cardiovascular Surgery Clinic, Pirogov National Medical and Surgical Center and the Center for Cardiology and Cardiovascular Surgery, Rostov-on-Don. Ultrasound Doppler flowmetry was performed in all patients, the following indicators were evaluated: the average volumetric blood flow rate (MGF – mean graft flow), the pulsation index (PI – pulsation index) and the percentage of diastolic volume filling (DF – diastolic filling). Coronaroshuntography was performed in 29 patients in the early postoperative period (within 2–6 hours after surgery). The comparison of angiographic data (slowing of blood flow through the shunt, stenosis, occlusion) with intraoperative parameters of ultrasound flowmetry was carried out. Results . 405 primary intraoperative flowmetry samples were analyzed in 188 patients with diffuse coronary lesion. It was found that 19.7 % of intraoperative flowmetry indicators were less than the recommended values: 9.3 % of autoarterial and 25 % of autovenous shunts to the anterior descending artery; 20.8 % of autovenous shunts to the diagonal artery; 33.3 % – to the envelope and 21.9 % – to the right coronary artery. In 21 % of the observations, technical problems were identified (defect of proximal or distal anastomoses; bend of the conduit; dissection of the autoarterial shunt), which were eliminated; in other cases, no technical problems were identified. When comparing the data of intraoperative ultrasound flowmetry and shuntography in the early postoperative period, statistical differences were revealed in patients with normal patency of venous shunts and their dysfunction: MGF 53±18 (46–59) vs. 38±15 (29–47), p=0.014; PI: 3±1 (2–3) vs. 7±1 (6–8), p≤0.001; DF: 79±15 (64–91) vs. 48±17 (41–60), p=0.005. There are differences in the flowmetry of autoarterial shunts depending on the risk of their dysfunction: MGF 32±11 (28–44) vs. 20±5 (13–24), p=0.005; PI: 2±1 (1–4) vs. 7±2 (5–9), p≤0.001; DF: 70±12 (61–85) vs. 50±15 (45–64), p=0.005. Conclusion . Intraoperative ultrasound flowmetry is a safe and effective tool for assessing blood flow through conduits during coronary bypass surgery in pa
介绍。近几十年来,冠状动脉疾病和弥漫性冠状动脉疾病的患者数量明显增加。由于冠状动脉床病变的性质,对此类患者进行全容量心肌血运重建术并不总是可能的,而且术后早期发生分流功能障碍的风险仍然很高。因此,在冠状动脉搭桥手术中使用超声术中血流测量是特别必要的,但最佳的移植物通畅指标问题仍未解决。目的是评价术中超声血流测量在弥漫性冠状动脉床病变患者中的应用可能性。方法与材料。该研究包括188例弥漫性冠状动脉床病变患者,他们在St. George胸外科和心血管外科诊所、Pirogov国家医学和外科中心以及顿河畔罗斯托夫心脏病学和心血管外科中心接受了冠状动脉搭桥手术。所有患者均行超声多普勒血流测量,评估平均容积血流量(MGF -平均移植物流量)、脉动指数(PI -脉动指数)和舒张期容积充盈率(DF -舒张期充盈)。29例患者术后早期(术后2-6小时内)行冠状动脉造影。将血管造影数据(分流、狭窄、闭塞血流减慢)与术中超声血流测量参数进行比较。结果。对188例弥漫性冠状动脉病变患者的405份术中血流测量样本进行分析。发现19.7%的术中血流指标低于推荐值:9.3%的自体动脉和25%的自体静脉分流至前降支;20.8%的自体静脉分流至斜动脉;33.3%到包膜,21.9%到右冠状动脉。在21%的观察中,发现了技术问题(近端或远端吻合缺损;导管的弯曲;剥离的自体动脉分流),这是消除;在其他情况下,没有发现任何技术问题。术中超声血流仪与分流术术后早期数据比较,静脉分流术通畅正常患者与分流术功能障碍患者的MGF差异有统计学意义:MGF 53±18(46-59)比38±15 (29-47),p=0.014;PI: 3±1 (2-3)vs. 7±1 (6-8),p≤0.001;DF: 79±15(64-91)比48±17 (41-60),p=0.005。自身动脉分流术的血流测量差异取决于其功能障碍的风险:MGF 32±11 (28-44)vs 20±5 (13-24),p=0.005;PI: 2±1 (1 - 4)vs. 7±2 (5-9),p≤0.001;DF: 70±12(61-85)比50±15 (45-64),p=0.005。结论。术中超声血流仪是一种安全有效的工具,用于评估冠状动脉疾病和弥漫性冠状动脉床病变患者在冠状动脉搭桥术中通过导管的血流。根据我们的研究,预测术后早期分流正常通畅时,胸内动脉靶MGF≥28 ml/min,静脉分流≥65 ml/min,各类导管靶MGF≤5.0,自体动脉分流靶DF≥60%,自体静脉移植靶DF≥68%为宜。
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引用次数: 0
Immediate results of combined coronary bypass surgery and aortic valve replacement with incomplete and complete myocardial revascularization 冠状动脉搭桥手术和主动脉瓣置换术合并不完全和完全心肌血运重建的即时结果
Q4 Medicine Pub Date : 2023-02-17 DOI: 10.24884/0042-4625-2023-182-1-57-64
V. S. Litus, D. G. Gramatikov
Introduction . Coronary heart disease and aortic valve stenosis still occupy a leading position among cardiovascular diseases. Against the background of an increase in life expectancy, patients with a combined pathology of the heart are increasingly appearing. Without surgical treatment, such patients have an unfavorable prognosis of life with a high mortality rate. Simultaneous surgical correction of coronary heart disease and aortic valve stenosis is a treatment method that can improve the prognosis and prolong the life of a patient. At the same time, combined interventions remain higher-risk operations compared to isolated aortic valve replacement and isolated coronary artery bypass grafting. The Objective was to evaluate the effect of incomplete and complete myocardial revascularization on the immediate results of surgical correction of combined pathology of the aortic valve and coronary arteries. Methods and Materials . For the period from 2017 until June 2022, 62 aortic valve replacement operations in combination with coronary artery bypass grafting were performed in the cardiac surgery department of the Leningrad Regional Clinical Hospital. The operated patients were divided into two groups. The group 1 included (n=32) patients who underwent aortic valve replacement and complete myocardial revascularization. The group 2 included patients (n=30) who underwent aortic valve replacement and incomplete myocardial revascularization. Results . Postoperative periods in both groups, according to the structure of early postoperative complications, are generally similar. The mortality rate in both groups did not exceed the predicted mortality rate and corresponded to the data of various literary sources. Conclusion . Our observation data showed that the mortality rate in the early postoperative period, in combined operations, does not depend on the completeness of revascularization in combined operations of coronary artery bypass grafting and aortic valve replacement. It is necessary to perform as complete myocardial revascularization in combined operations as technically feasible and appropriate in a clinical situation.
介绍。冠心病和主动脉瓣狭窄在心血管疾病中仍占主导地位。在预期寿命增加的背景下,患有心脏综合病理的患者越来越多。如不进行手术治疗,患者预后不良,死亡率高。冠心病主动脉瓣狭窄同时手术矫正是一种改善预后、延长患者生命的治疗方法。与此同时,与孤立主动脉瓣置换术和孤立冠状动脉旁路移植术相比,联合干预仍然是高风险的手术。目的是评价不完全心肌血运重建术和完全心肌血运重建术对主动脉瓣冠状动脉联合病变手术矫正即刻效果的影响。方法与材料。2017年至2022年6月期间,列宁格勒地区临床医院心脏外科进行了62例主动脉瓣置换术联合冠状动脉搭桥术。手术患者分为两组。第1组包括(n=32)行主动脉瓣置换术和完全心肌血运重建术的患者。第二组包括30例接受主动脉瓣置换术和不完全心肌血运重建术的患者。结果。两组术后时间根据术后早期并发症的结构大致相似。两组的死亡率均未超过预测死亡率,与各种文献资料相符。结论。我们的观察数据表明,在联合手术中,术后早期的死亡率并不取决于冠状动脉搭桥术和主动脉瓣置换术联合手术的血运重建的完整性。在技术上可行和临床条件合适的情况下,联合手术进行完全心肌血运重建术是必要的。
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引用次数: 0
Real and predicted lung function after anatomical lung resections (review of literature) 解剖性肺切除术后肺功能的真实和预测(文献综述)
Q4 Medicine Pub Date : 2021-08-20 DOI: 10.24884/0042-4625-2021-180-2-93-100
A. Akopov, S. Cherny, Ritu Mishra, M. Kovalev
The function of the respiratory parenchyma remaining after lung resection is one of the determining factors of the immediate result of the operation and the postoperative quality of life. A number of studies have been conducted to objectify the preoperative prognosis of the functional safety limit of thoracic interventions using a variety of methods and formulas. Unfortunately, until now, there is no convincing data on the correctness of at least one of the proposed methods for predicting respiratory function. The process of rehabilitation of postoperative ventilation function in the lungs is affected not only by the volume of parenchymal resection, but also by the area of resection, the method and trauma of access, the severity of emphysema, intraoperative trauma of mediastinal structures, postoperative progression of pulmonary fibrosis, etc., and video assisted surgery and segmental resections do not provide an obvious functional advantage in the long term after operations. During the first year after anatomical resection of the lung, functional indicators usually improve. Reasons (or reason) of such improvements are not always clear and may be associated with compensatory growth of the pulmonary parenchyma in a number of patients.
肺切除术后残存的呼吸实质功能是决定手术即时效果和术后生活质量的因素之一。许多研究使用各种方法和公式来客观评价胸部介入手术功能安全限度的术前预后。不幸的是,到目前为止,还没有令人信服的数据证明至少一种预测呼吸功能的方法是正确的。术后肺通气功能的恢复过程不仅受实质切除体积的影响,还受切除面积、通路方式和创伤、肺气肿严重程度、术中纵隔结构损伤、术后肺纤维化进展等因素的影响,视频辅助手术和节段性切除在术后长期内并不能提供明显的功能优势。解剖切除肺后的第一年,肺功能指标通常有所改善。这种改善的原因(或原因)并不总是明确的,可能与一些患者肺实质代偿性生长有关。
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引用次数: 0
Cystic adventitial disease of the popliteal artery and ILIAC vein 腘动脉和ILIAC静脉囊性外膜疾病
Q4 Medicine Pub Date : 2021-06-02 DOI: 10.24884/0042-4625-2021-180-1-100-103
A. V. Borodulin, S. M. Lazarev, A. G. Kazarenko, L. V. Makar, A. Y. Kolesnichenko, E. Y. Lazareva, D. Chernishev
These two cases of successful treatment of a rare vascular disorder – cystic adventitial disease (CAD). Case 1: CAD of the popliteal artery with narrowing of the popliteal artery and intermittent claudication. Case 2: CAD of iliac vein with irreducible femoral hernia formation and iliac vein subocclusion. We described preoperative planning, surgical intervention and postoperative management in our cases. Surgery after careful preoperative planning is only one effective method of treatment of CAD and has good long-term results.
这两个病例成功治疗了一种罕见的血管疾病-囊外膜病(CAD)。病例1:腘动脉CAD伴腘动脉狭窄,间歇性跛行。病例2:髂静脉CAD合并股疝形成及髂静脉亚闭合。我们描述了我们病例的术前计划、手术干预和术后管理。术前精心规划后的手术是治疗CAD的唯一有效方法,长期效果良好。
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引用次数: 0
Multidisciplinary approach to surgical treatment and rehabilitation of patients with defects of the anterior tracheal wall 气管前壁缺损的多学科手术治疗与康复
Q4 Medicine Pub Date : 2021-06-02 DOI: 10.24884/0042-4625-2021-180-1-31-39
O. Eshonkhodjaev, Shuhrat Khudaybergenov, R. Hayaliev
The objective was to improve the results of treatment of patients with persistent defects of the anterior tracheal wall and soft tissues of the neck.Methods and materials. 220 patients with tracheal cicatrical stenosis were treated, of which 120 patients had defects of the anterior tracheal wall of various sizes. In 70% of cases, PCT was postintubation/posttracheostomy. Men predominated – 89 (74.2 %), women – 31 (25.8 %). After a routine examination, including endoscopic examination, MSCT of the chest with the capture of the cervical region, and general clinical diagnostic methods, all patients underwent surgical treatment.Results. According to the nature of the elimination of the defect of the anterior tracheal wall, patients were divided into several groups. Both local plastic surgery and the elimination of the tracheal defect with the use of microsurgical techniques were used. Circular resection of the trachea with the elimination of the defect was performed in 5 cases. In 2 cases, in the presence of a large persistent defect of more than 6 cm in size, a composite pre-fabricated deltopectoral skin-fascial-cartilage flap was used.Conclusion. The choice of a method for eliminating a persistent open defect of the anterior tracheal wall is determined individually in each case, it depends on its size, the depth of the airway lumen, and the condition of the surrounding tissues. The use of displaced skin-fascial flaps on the vascular pedicle for closing the tracheal defect allows to restore the mucous membrane of the tracheal defect area without using the surrounding scar tissue and close the defect with a second flap without straining the edges of the wound.
目的是提高持续性气管前壁和颈部软组织缺损患者的治疗效果。方法和材料。对220例气管瘢痕性狭窄患者进行了治疗,其中120例患者存在各种大小的气管前壁缺损。在70%的病例中,PCT是气管插管后/气管造口术后。男性占多数——89人(74.2%),女性占31人(25.8%)。在常规检查后,包括内窥镜检查、胸部MSCT(捕获颈部)和一般临床诊断方法,所有患者都接受了手术治疗。后果根据消除气管前壁缺损的性质,将患者分为几个组。采用了局部整形手术和显微外科技术消除气管缺损。对5例患者进行了气管环形切除并消除了缺损。在2例病例中,在存在大于6cm大小的大的持续性缺损的情况下,使用预制的复合三角肌皮肤筋膜软骨瓣。结论消除气管前壁持续开放性缺损的方法的选择在每种情况下都是单独确定的,这取决于其大小、气道管腔的深度和周围组织的状况。在血管蒂上使用移位的皮肤筋膜瓣来闭合气管缺损允许在不使用周围瘢痕组织的情况下恢复气管缺损区域的粘膜,并且在不拉紧伤口边缘的情况下用第二皮瓣闭合缺损。
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引用次数: 0
Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine 圣彼得堡I.I. Dzhanelidze急救医学研究所
Q4 Medicine Pub Date : 2021-06-02 DOI: 10.24884/0042-4625-2021-180-1-104-106
A. N. Tulupov, M. I. Safoev, A. A. Esenokov, L. I. Karimova, M. Y. Boeva, M. Z. Yarmagomedov
Rectal wound occurs in 1 to 5 % of cases among wounds of the abdominal organs. In patient B., 32 years old, 3 days after a stab wound to the left gluteal region and after ligation of the internal iliac artery with an extraperitoneal approach to stop ongoing bleeding, rectoromanoscopy and chromovulneroscopy revealed damage to the rectal wall measuring 1.2×0.7 cm at a height of 15 cm from the anus. The defect in the rectal wall was closed using endoscopic clips (6 pcs.). The wound canal of the left gluteal region was overdrained. At the control examination of the rectum on the 20th day after suturing the defect with endoscopic clips, the intestinal wall was sealed. The wound in the gluteal region healed by secondary intention. The patient was discharged from the hospital after 3 weeks. This method of endoscopic clipping of a rectal wound with external drainage of the wound canal is a modern minimally invasive method of treatment and can be used as an alternative to sigmoidostomy. The obvious advantages of this method of treatment are: improving the patient’s quality of life, the absence of the need for additional surgical interventions in order to restore the continuity of the colon.
在腹部脏器伤口中,直肠伤口的发生率为1% ~ 5%。患者B, 32岁,左臀区被刺伤3天后,采用腹膜外入路结扎髂内动脉止血后,直肠瘤镜检查和染色神经镜检查显示,在距离肛门15cm处,直肠壁损伤1.2×0.7 cm。用内窥镜夹(6个)缝合直肠壁缺损。左臀区伤口管引流过度。内镜夹缝合缺损后第20天直肠对照检查,封闭肠壁。臀区伤口经二次穿刺愈合。病人3周后出院。这种内窥镜夹持直肠伤口并对伤口管进行外部引流的方法是一种现代微创治疗方法,可作为乙状结肠造口术的替代方法。这种治疗方法的明显优点是:提高了患者的生活质量,不需要额外的手术干预来恢复结肠的连续性。
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引用次数: 9
Robotic thoracoscopic parathyroidectomy for ectopic mediastinal parathyroid adenoma 机器人胸腔镜下异位纵隔甲状旁腺瘤切除术
Q4 Medicine Pub Date : 2021-06-02 DOI: 10.24884/0042-4625-2021-180-1-89-93
P. Yablonsky, A. Kuzmichev, E. Shepichev, A. L. Akinchev, Z. Matveeva
The publication presents the successful experience of using the DaVinci robotic system for the treatment of persistent hyperparathyroidism caused by mediastinal ectopic parathyroid adenoma in 62 years old female patient. The role of single photon emission computed tomography in diagnostics was demonstrated.
本文介绍了使用达芬奇机器人系统治疗62岁女性纵隔异位甲状旁腺瘤所致持续性甲状旁腺功能亢进的成功经验。证明了单光子发射计算机断层扫描在诊断中的作用。
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引用次数: 0
Transsphenoidal endoscopic treatment of cysts of the chiasmo-sellar region 经蝶窦内镜治疗鞍交叉区囊肿
Q4 Medicine Pub Date : 2021-06-02 DOI: 10.24884/0042-4625-2021-180-1-10-16
N. Puzakov, V. Cherebillo, I. Tregubenko
Introduction. Cysts of the chiasmo-sellar region include Rathke cleft cysts, colloid cysts, arachnoid cysts, dermoid cysts, and epidermoid cysts.The objective was to determine the specific features of surgical treatment for each type of cysts of the chiasmo-sellar region, allowing to achieve the best postoperative results.Methods and materials. During the period from 2009 to 2018, 57 patients with cysts of the chiasmo-sellar region were examined and treated. All patients underwent transsphenoidal endoscopic treatment of cysts of the chiasmo-sellar region.Results. Among 57 operated patients, follow-up observation revealed only 2 relapses.Conclusion. For each type of cysts of the chiasmal-sellar region, there are specific features of surgical treatment that allow to achieve the best postoperative results.
介绍。交叉鞍区囊肿包括Rathke裂性囊肿、胶质囊肿、蛛网膜囊肿、皮样囊肿和表皮样囊肿。目的是确定每种类型的交叉鞍区囊肿的手术治疗的具体特征,以达到最佳的术后效果。方法和材料。2009年至2018年,对57例交叉鞍区囊肿患者进行了检查和治疗。所有患者均行经蝶窦内窥镜治疗交叉鞍区囊肿。57例手术患者中,随访观察复发2例。对于每一种类型的交叉鞍区囊肿,都有特定的手术治疗特点,以达到最佳的术后效果。
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引用次数: 0
Influence of the gastric stump’s volume on the long-term results of laparoscopic Roux-en-Y gastric bypass surgery 残胃体积对腹腔镜Roux-en-Y胃旁路术远期疗效的影响
Q4 Medicine Pub Date : 2021-06-02 DOI: 10.24884/0042-4625-2021-180-1-81-88
A. Khitaryan, D. Melnikov, A. Orekhov, A. Mezhunts, S. A. Adizov, А. A. Abovyan
The objective was to retrospectively analyze the dependence of long-term results of laparoscopic Roux-en-Y gastric bypass surgery according to the size of the formed gastric stumpMethods and materials. We retrospectively analyzed the long-term results of 207 morbidly obese patients who underwent laparoscopic Roux-en-Y gastric bypass surgery by two different techniques. The median follow-up was 36 months. Two groups of patients were identified according to the method of formation of the gastric stump: using 2 (1st group) or 3 (2nd group) stapler cassettes and performing of computed tomography volumetry to determine thevolume of the created gastric stump.Results. Statistically significant differences in the volume of the formed gastric stump, depending on the method of operation, were as follows: 23.8 ml (8.9–37.3 ml) in the 1st group and 47.7 ml (31.9–72.8 ml) in the 2nd group (p<0.0001). Significant differences were observed in the following indicators: relapse of weight gain or insufficient weight loss (loss of < 70 % overweight) at median follow-up of 36 months were observed in 2 (2.3 %) and 12 (9.9 %) cases in the 1st and 2nd groups, respectively (p<0.05).Conclusion. We revealed that the formation of the gastric stump of a very small volume by 2 stapler cassettes compared to using 3 stapler cassettes contributes to improving the results in the long-term postoperative period and minimizing the frequency of relapse of weight gain and insufficient weight loss. The restrictive component of the surgery with equal malabsorptive is fundamental for the clinical parameters of its effectiveness, that leads to increasing the frequency of relapses of weight gain and insufficient weight loss in the 2nd group in comparison with the 1st and group of patients (p<0.05). Based on computed tomography volumetry, the volume of a small-sized stomach stump can be reliably measured and, accordingly, weight loss is predicted in the long term after the surgery, as well as the absence of relapses of weight gain or insufficient weight loss.
目的是根据形成的胃残端的大小,回顾性分析腹腔镜Roux-en-Y胃旁路手术的长期结果的相关性。方法和材料。我们回顾性分析了207例病态肥胖患者采用两种不同技术进行腹腔镜Roux-en-Y胃旁路手术的长期结果。中位随访时间为36个月。根据残胃的形成方法,确定了两组患者:使用2个(第一组)或3个(第二组)吻合器暗盒,并进行计算机断层扫描体积测定,以确定形成的残胃的体积。后果所形成的胃残端的体积根据手术方法而存在统计学上的显著差异,结果如下:第一组23.8毫升(8.9-37.3毫升),第二组47.7毫升(31.9-72.8毫升)(p<0.0001)。在以下指标上观察到显著差异:第一组和第二组分别有2例(2.3%)和12例(9.9%)在中位随访36个月时重量增加或体重减轻不足(体重减轻<70%)复发,结论:与使用3个吻合器相比,使用2个吻合机形成体积非常小的胃残端有助于改善长期术后的效果,并将体重增加和体重减轻不足的复发频率降至最低。具有同等吸收不良的手术的限制性成分是其有效性的临床参数的基础,与第一组和第二组患者相比,第二组的体重增加和体重减轻不足的复发频率增加(p<0.05),可以可靠地测量小型胃残端的体积,因此,可以预测手术后的长期体重减轻,以及不会出现体重增加或体重减轻不足的复发。
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引用次数: 1
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Vestnik khirurgii imeni I. I. Grekova
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