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Influence of pseudoxanthoma elasticum on the lipid profile and prognostic implications. 假黄瘤对血脂谱的影响及预后意义。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 Epub Date: 2024-07-17 DOI: 10.1024/0301-1526/a001134
Max Jonathan Stumpf, Tim Winkler, Marit Siebigteroth, Annemarie Lenzen, Leonie Weinhold, Georg Nickenig, Doris Hendig, Dirk Skowasch, Nadjib Schahab, Christian A Schaefer

Background: Pseudoxanthoma elasticum (PXE) is a rare, inherited disease characterised by specific skin lesions, progressive loss of vision and early onset atherosclerosis. Atherosclerosis in PXE leads to an increased rate of vascular occlusion and severe intermittent claudication. Although genetically determined, the individual course of PXE is highly variable. Up to now, there is no sufficient parameter to identify individuals at risk of rapid disease progression. This present study focused the lipid profile of patients with PXE and its possible influence on the clinical severity of peripheral artery disease (PAD). Patients and methods: 112 patients with PXE were retrospectively screened. Patients without a complete lipid profile consisting of total cholesterol (TC), triglycerides (TGC), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and Lipoprotein(a) (Lp[a]) where excluded as well as patients with already initiated lipid-lowering therapy. 52 patients met the inclusion criteria. An age-adjusted ordinal regression model was applied to determine the association of each lipid fraction with the severity of PAD assessed as Fontaine classification. Results: The lipid profile of patients with PXE was unremarkable (TGC: 135.8±105.8 mg/dl; TC: 172.5±44.4 mg/dl; HDL: 63.0±18.2 mg/dl; Lp[a]: 64.7±93.5 nmol/l). Ordinal regression showed a significant association of Lp(a) with the severity of PAD with an odds ratio of 1.01 (1.00-1.02; p = 0.004), whereas the other fractions of the lipid profile had no significant influence. Conclusions: This study provides the largest evaluation of blood lipids up to now and the first characterization of Lp(a) levels in patients with PXE. We were able to provide first evidence of a correlation between elevated levels of Lp(a) and the severity of PAD. The present results suggest that determination of Lp(a) in early stages of PXE could help to identify patients at risk of rapid disease progression and with the need of intensified walking exercise training.

背景:假黄疽(PXE)是一种罕见的遗传性疾病,其特征是特殊的皮肤损伤、进行性视力丧失和早发性动脉粥样硬化。PXE 中的动脉粥样硬化会导致血管闭塞率升高和严重的间歇性跛行。虽然 PXE 是由基因决定的,但其个体病程变化很大。到目前为止,还没有足够的参数来识别疾病快速进展的风险个体。本研究的重点是 PXE 患者的血脂状况及其对外周动脉疾病(PAD)临床严重程度的可能影响。患者和方法:对 112 名 PXE 患者进行了回顾性筛查。排除了没有完整血脂谱(包括总胆固醇(TC)、甘油三酯(TGC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)和脂蛋白(a)(Lp[a]))的患者以及已经开始降脂治疗的患者。52 名患者符合纳入标准。应用年龄调整后的序数回归模型来确定每种血脂组分与根据方丹分级评估的 PAD 严重程度之间的关系。结果PXE患者的血脂谱无异常(TGC:135.8±105.8 mg/dl;TC:172.5±44.4 mg/dl;HDL:63.0±18.2 mg/dl;Lp[a]:64.7±93.5 nmol/l)。正回归结果显示,脂蛋白[a]与 PAD 的严重程度有显著相关性,几率比为 1.01 (1.00-1.02; p = 0.004),而血脂组合的其他部分则没有显著影响。结论:这项研究提供了迄今为止最大规模的血脂评估,并首次描述了 PXE 患者的脂蛋白(a)水平。我们首次证明了脂蛋白(a)水平升高与 PAD 严重程度之间的相关性。本研究结果表明,在 PXE 早期阶段测定脂蛋白(a)有助于识别有疾病快速进展风险和需要加强步行锻炼训练的患者。
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引用次数: 0
Efficacy and safety of aspirin in venous thromboembolism prevention after total hip arthroplasty, total knee arthroplasty or fracture. 阿司匹林在全髋关节置换术、全膝关节置换术或骨折后预防静脉血栓栓塞的有效性和安全性。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1024/0301-1526/a001129
Wei Jiang, Yici Yan, Tongmin Huang, Zhenyi Lin, Xinyan Yang, Zhouqing Luo, Lin Ye

Background: This study aims to analyse the efficacy and safety of aspirin in the prevention of venous thromboembolism (VTE) for patients undergoing total hip arthroplasty (THA), total knee arthroplasty (TKA) or fracture. Patients and methods: Two independent investigators searched PubMed, Embase, Cochrane and ClinicalTrials.gov from January 2000 to June 2023 to retrieve randomized control trials (RCTs) about aspirin in VTE prevention after arthroplasty or fracture. Then, the relative risk (RR) was utilized to evaluate its efficiency and safety. Results: A total of 16 RCTs with 27,864 patients were included. There was no statistical difference in the incidence of deep-vein thrombosis (RR: 1.31, p = 0.100), pulmonary embolism (RR:1.05, p = 0.850), VTE (RR:1.28, p = 0.290), major bleeding (RR:0.96, p = 0.900), and death (RR:1.01, p = 0.960) between the aspirin group and the anticoagulants group. Subgroup analysis showed that a relatively higher incidence of deep-vein thrombosis in patients undergoing TKA (RR:1.49, p = 0.030), fracture (RR:1.48, p = 0.001), patients receiving 81 mg aspirin twice daily (RR:1.48, p = 0.001) and patients from North America (RR:1.57, p<0.001) when comparing aspirin with anticoagulants. Meanwhile, the incidence of VTE was higher in patients receiving 100 mg aspirin once daily (RR:1.82, p<0.001) compared with anticoagulants. Additionally, the incidence of all bleeding (RR:2.00, p = 0.030) was higher in patients receiving aspirin in Asia compared with anticoagulants. Conclusions: In terms of clinical effectiveness and safety, aspirin (antiplatelet agent) was generally not inferior to anticoagulants in the prevention of VTE after THA, TKA, or fracture. Notably, the clinical effectiveness of aspirin was affected by different surgical types, the doses of aspirin and races.

研究背景本研究旨在分析阿司匹林对接受全髋关节置换术(THA)、全膝关节置换术(TKA)或骨折患者预防静脉血栓栓塞症(VTE)的有效性和安全性。患者和方法:两位独立研究者检索了2000年1月至2023年6月期间的PubMed、Embase、Cochrane和ClinicalTrials.gov,以检索有关阿司匹林预防关节置换术或骨折后VTE的随机对照试验(RCT)。然后,利用相对风险(RR)评估其有效性和安全性。结果:共纳入 16 项 RCT,27864 名患者。阿司匹林组和抗凝药物组在深静脉血栓(RR:1.31,P = 0.100)、肺栓塞(RR:1.05,P = 0.850)、VTE(RR:1.28,P = 0.290)、大出血(RR:0.96,P = 0.900)和死亡(RR:1.01,P = 0.960)的发生率上没有统计学差异。亚组分析显示,接受TKA手术(RR:1.49,p = 0.030)、骨折(RR:1.48,p = 0.001)、每日两次服用81毫克阿司匹林(RR:1.48,p = 0.001)和来自北美的患者(RR:1.57,pConclusions)的深静脉血栓形成发生率相对较高:就临床有效性和安全性而言,在预防 THA、TKA 或骨折后 VTE 方面,阿司匹林(抗血小板药物)的效果一般不劣于抗凝药物。值得注意的是,阿司匹林的临床有效性受到不同手术类型、阿司匹林剂量和种族的影响。
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引用次数: 0
Percutaneous transluminal angioplasty of femoropopliteal veins for treatment of post-thrombotic syndrome. 治疗血栓后综合征的股静脉经皮腔内血管成形术。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 Epub Date: 2024-07-17 DOI: 10.1024/0301-1526/a001136
Stephanie Zbinden, Doerte Wyss, Simon Wolf, Nils Kucher, Erik W Holy

Background: Controversy persists concerning the endovascular treatment of the post-thrombotic syndrome (PTS), particularly if femoropopliteal veins are involved. Methods: We screened consecutive patients with PTS who underwent percutaneous transluminal angioplasty (PTA) of femoropopliteal veins using posterior tibial or popliteal vein access who had at least 3-month follow-up. Our assessment included the evaluation of primary and secondary patency of the treated segments by Doppler ultrasound (DUS) and clinical outcomes measured by the change in Villalta score as well as ulcer healing. Results: Among 29 patients, 8 (27.7%) were women and the mean (SD) age was 53.3 (13.6) years. Posterior tibial vein and popliteal access were used in 26 (89.7%) and 3 patients (10.3%), respectively. 13 (44.8%) patients had prior (n = 11, 37.9%) or concomitant (n = 9, 31.0%) endovascular treatment of the iliac or common femoral veins. At a median follow-up of 395 days (Q1: 205-Q3: 756 days), primary patency of femoropopliteal veins was 79.3% (95% CI 64.6-94.1%) and secondary patency was 82.8% (95% CI, 69.0-96.5%). The percentage of patients with moderate or severe PTS according to the Villalta score decreased from baseline to last follow-up from 34.5% to 18.5% and from 31% to 14.8%, respectively (p<0.003). Overall, the mean (SD) Villalta score decreased from 11.5 (1.7) to 8.0 (1.7) (p<0.0001). Postprocedural complete ulcer healing occurred in 4 out of 5 (80%) patients. Two (6.9%) patients developed new ulcers. No major bleeding, pulmonary embolism, stroke, or death occurred. Conclusion: PTA of femoropopliteal veins via posterior tibial or popliteal vein access appears to improve the severity of PTS with acceptable patency rates.

背景:关于血栓后综合征(PTS)的血管内治疗,尤其是涉及股骨干静脉时,一直存在争议。方法我们筛选了使用胫后静脉或腘静脉入路接受经皮腔内血管成形术(PTA)的股腘静脉血栓后综合征患者,并对其进行了至少 3 个月的随访。我们的评估包括通过多普勒超声(DUS)评估治疗区段的一次和二次通畅情况,以及通过 Villalta 评分变化和溃疡愈合情况衡量的临床结果。结果:29 名患者中,8 名(27.7%)为女性,平均(标清)年龄为 53.3(13.6)岁。分别有 26 名(89.7%)和 3 名(10.3%)患者使用了胫后静脉和腘静脉入路。13例(44.8%)患者之前(11例,37.9%)或同时(9例,31.0%)接受过髂静脉或股总静脉的血管内治疗。中位随访时间为 395 天(第一季度:205-第三季度:756 天),股总静脉一次通畅率为 79.3%(95% CI 为 64.6-94.1%),二次通畅率为 82.8%(95% CI 为 69.0-96.5%)。根据Villalta评分,中度或重度PTS患者的比例从基线到最后一次随访分别从34.5%降至18.5%和从31%降至14.8%(P结论:通过胫后静脉或腘静脉入路对股网膜静脉进行 PTA 似乎能改善 PTS 的严重程度,且通畅率可接受。
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引用次数: 0
Anticoagulation in embolic acute limb ischaemia-an observational study. 栓塞性急性肢体缺血的抗凝治疗--一项观察性研究。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 Epub Date: 2024-09-09 DOI: 10.1024/0301-1526/a001147
Aishan Patil, Dean T Williams, Ayoub Gomati, John Nagy

The management of embolic acute limb ischaemia commonly involves determining aetiology and performing emergency invasive procedures. This detailed study aimed to determine the impact of manipulation of anticoagulation in the aetiology of emboli in acute limb ischaemia and determine the efficacy of primary anticoagulation therapy vs. invasive interventions. Material and methods: Data collection was conducted at a single institution on a cohort of patients presenting consecutively with embolic acute limb ischaemia over one year. Two groups were compared, one receiving anticoagulation as primary therapy with those undergoing invasive treatment as the internal comparison group. Results: A likely haematological causation was identified in 22 of 38 presentations, related to interruption of anticoagulation in cardiac conditions, the majority atrial fibrillation (n=12), or hypercoagulable states (n=10). Limb salvage was pursued in 36 patients employing anticoagulation (n=19) or surgical embolectomy (n=17) as the primary therapy in upper and lower limbs (n=17 vs n=19 respectively). Despite delays often well beyond six hours and a range of ischaemic severity in both groups, 35 of 36 patients achieved full or substantive restoration of function with improved perfusion. Regarding anatomical distribution of arterial disease and therapy, three patients with multi-level disease proceeded to embolectomy following anticoagulation. Embolectomy was undertaken most often for proximal emboli and more profound paralysis. Conclusions: Anticoagulation and coagulopathy are commonly implicated in the aetiology of arterial emboli, with omission of effective anticoagulation in atrial fibrillation being associated in almost 1/3 of presentations. Whilst more profound limb paralysis and proximal or multi-level disease tended to be managed surgically, primary anticoagulation therapy alone or with a secondary embolectomy was effective across the spectrum of ischaemia severity and despite significant delays beyond guideline recommendations.

栓塞性急性肢体缺血的治疗通常包括确定病因和实施紧急侵入性手术。这项详细研究旨在确定抗凝操作对急性肢体缺血栓塞病因的影响,并确定初级抗凝治疗与侵入性干预的疗效。材料和方法:在一家医疗机构对一年内连续出现栓塞性急性肢体缺血的患者进行数据收集。两组患者进行了比较,一组接受抗凝疗法作为主要疗法,另一组接受侵入性治疗作为内部比较组。研究结果在 38 例病例中,有 22 例可能与血液学病因有关,与心脏疾病中断抗凝有关,其中大多数为心房颤动(12 例)或高凝状态(10 例)。36 名患者采用抗凝(19 人)或外科栓子切除术(17 人)作为上肢和下肢的主要疗法(分别为 17 人和 19 人),以挽救肢体。尽管两组患者的治疗延迟时间往往超过六小时,缺血严重程度也不尽相同,但 36 名患者中有 35 人的功能得到完全或实质性恢复,灌注也得到改善。关于动脉疾病的解剖分布和治疗,有三名多层次疾病患者在抗凝治疗后进行了栓子切除术。栓子切除术多用于近端栓子和更严重的瘫痪。结论动脉栓塞的病因通常与抗凝和凝血功能障碍有关,近三分之一的病例与心房颤动患者未进行有效抗凝有关。虽然更严重的肢体瘫痪和近端或多层次的疾病倾向于通过手术治疗,但在各种缺血严重程度的情况下,单纯的初级抗凝治疗或辅以栓子切除术都是有效的,尽管存在超出指南建议的严重延误。
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引用次数: 0
53. Jahrestagung der Deutschen Gesellschaft für Angiologie - Gesellschaft für Gefäßmedizin e.V. und 8. DGA-Interventionskongress. 第 53 届德国血管学会-血管医学学会年会暨第 8 届 DGA 干预大会。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 DOI: 10.1024/0301-1526/a001152
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引用次数: 0
Fluid dynamics and venous hemodynamics in the lower extremities. 下肢流体动力学和静脉血液动力学。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 Epub Date: 2024-08-14 DOI: 10.1024/0301-1526/a001141
Hakan Guven

Chronic venous disease is a vascular disorder characterized by impaired venous return and a progressive dysfunction of the venous system. Pathological reflux can occur due to abnormal dilation and weakening of the vein wall. The circulatory system is a natural structure in which physical laws, such as the law of closed containers and gravity, operate. The malfunctions in the system also adhere to these laws of nature. This article explains how the principles of fluid dynamics apply to the flow of blood in the veins of the legs. I am discussing the principles of Pascal's law, Torricelli's law, Bernoulli's law, and Poiseuille's law, and how they are relating to the anatomy and physiology of the venous system.

慢性静脉疾病是一种血管疾病,其特点是静脉回流受阻和静脉系统功能逐渐失调。由于静脉壁的异常扩张和减弱,会出现病理性回流。循环系统是一个自然结构,其中有物理定律,如封闭容器定律和重力定律。系统中的故障也遵循这些自然规律。本文将解释流体动力学原理如何应用于腿部静脉中的血液流动。我将讨论帕斯卡定律、托里切利定律、伯努利定律和普瓦捷定律的原理,以及它们与静脉系统解剖学和生理学的关系。
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引用次数: 0
Inferior vena cava filter implantation according to strength of clinical indication. 根据临床适应症的强度植入下腔静脉过滤器。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 DOI: 10.1024/0301-1526/a001144
Michele Dalla Vestra, Marta Zanon, Elisabetta Grolla, Andrea Tavernese, Giuliana Autiero, Marco Barbierato, Federico Ronco, Fabio Presotto
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引用次数: 0
Association of endothelial function and lower extremity perfusion in peripheral artery disease. 外周动脉疾病的内皮功能与下肢灌注的关系。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 Epub Date: 2024-07-09 DOI: 10.1024/0301-1526/a001131
Kangbo Li, Mengjun Dai, Mesud Sacirovic, Nikolaos Pagonas, Oliver Ritter, Janine Kah, Martin A Lauxmann, Peter Bramlage, Anja Bondke Persson, Ivo Buschmann, Philipp Hillmeister

Background: The current study aims to investigate the association between endothelial function and lower extremity perfusion in patients with peripheral artery disease (PAD). Patients and methods: In total 229 patients with PAD (Rutherford stage 0-3) were enrolled in the current study. Endothelial function was assessed by measuring flow-mediated dilation (FMD) and endothelial cell proliferation capacity (ECPC). Lower extremity perfusion was assessed by measuring oscillometry-based ankle brachial index (oABI) and pulse wave index (PWI). In addition, carotid intima-media-thickness (cIMT) was also measured as a surrogate marker for atherosclerosis. Correlations between FMD, ECPC, oABI, PWI, and cIMT were analysed using Pearson correlation coefficient. The relationship between the above variables and the severity of PAD was investigated using ordinal logistic regression analysis. Results: Correlation analysis showed that FMD negatively associated with PWI (r = -0.183, p = 0.005), ECPC positively associated with oABI (r = 0.162, p = 0.014), and oABI negatively associated with PWI (r = -0.264, p < 0.001). Ordinal logistic regression analysis showed that ECPC (β = -0.009, p = 0.048), oABI (β = -5.290, p < 0.001), and age (β = -0.058, p = 0.002) negatively associated with the PAD Rutherford stages. In addition, PWI (β = 0.006, p < 0.001), cIMT (β = 18.363, p = 0.043) positively associated with the PAD Rutherford stages. Conclusions: Endothelial function significantly associates with lower extremity perfusion in patients with PAD, and both are related to the severity of PAD.

研究背景本研究旨在探讨外周动脉疾病(PAD)患者的内皮功能与下肢血流灌注之间的关系。患者和方法共有 229 名 PAD 患者(卢瑟福 0-3 期)参加了本次研究。通过测量血流介导的扩张(FMD)和内皮细胞增殖能力(ECPC)来评估内皮功能。下肢血流灌注通过测量基于示波法的踝肱指数(oABI)和脉搏波指数(PWI)进行评估。此外,还测量了颈动脉内膜厚度(cIMT),作为动脉粥样硬化的替代指标。使用皮尔逊相关系数分析了 FMD、ECPC、oABI、PWI 和 cIMT 之间的相关性。使用序数逻辑回归分析研究了上述变量与 PAD 严重程度之间的关系。结果显示相关性分析表明,FMD 与脉搏波速度呈负相关(r = -0.183,p = 0.005),ECPC 与 oABI 呈正相关(r = 0.162,p = 0.014),oABI 与脉搏波速度呈负相关(r = -0.264,p < 0.001)。顺序逻辑回归分析显示,ECPC(β = -0.009,p = 0.048)、oABI(β = -5.290,p <0.001)和年龄(β = -0.058,p = 0.002)与 PAD Rutherford 分期呈负相关。此外,脉搏波速度指数(β = 0.006,p < 0.001)、cIMT(β = 18.363,p = 0.043)与 PAD Rutherford 分期呈正相关。结论内皮功能与 PAD 患者的下肢血流灌注密切相关,两者都与 PAD 的严重程度有关。
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引用次数: 0
Optimised CT Pulmonary angiography in pregnant women - first line or last resort? 优化孕妇 CT 肺血管造影--一线还是最后一招?
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-01 DOI: 10.1024/0301-1526/a001140
Anne Kolouschek, Max Jonathan Stumpf
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引用次数: 0
Deep vein thrombosis after sclerotherapy and endovenous laser ablation of varicose veins - an observational study. 静脉曲张硬化疗法和静脉腔内激光消融术后的深静脉血栓形成--一项观察性研究。
IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-07-01 Epub Date: 2024-06-13 DOI: 10.1024/0301-1526/a001130
Stefania Di Gangi, Carole Guillet, Florian Anzengruber, Stefan Zechmann, Thomas O Meier

Background: The risk of developing deep vein thrombosis (DVT) after endovenous ablation of varicose veins varies in the literature. Little is known about the characteristics of this complication and associated factors. This study aimed: 1) to study the occurrence of DVT after ultrasound-guided foam sclerotherapy (UGFS) alone or combined with endovenous laser ablation (EVLA) for lower-limb varicose veins; 2) to identify factors associated with DVT. Patients and methods: The study included all outpatients aged 18 years or older who underwent UGFS and EVLA or UGFS alone at the University Hospital of Zurich between 2011 and 2015. Data were extracted from the hospital electronic medical record. Patients were surveyed about their level of pain after the procedure and their level of satisfaction with the procedure. Duplex ultrasound was used to assess the deep venous system 7-10 days and 6-8 months after the procedure. Regression analysis was used to examine the association of patient and procedure characteristics with the development of DVT. Results: A total of 334 patients (561 procedures performed in 393 different sessions) were included: 73% of the patients underwent combined UGFS and EVLA and 27% underwent UGFS alone. DVT occurred in 24 (7.2%) patients, of whom 88% underwent combined procedures and 17% underwent interventions involving both the great and small saphenous veins on the same session. DVT occurred in 8.2% of patients receiving thromboprophylaxis and in 9.5% of patients not receiving thromboprophylaxis. DVT occurred in 5.2% of women and 11.9% of men. No factors associated with a diagnosis of DVT after intervention were identified. Pain and satisfaction levels did not differ between patients with and without DVT. Conclusions: This study adds to the knowledge of the risk of DVT following UGFS alone or combined with EVLA. Further studies are needed to revise thromboprophylaxis.

背景:文献中关于静脉曲张静脉腔内消融术后发生深静脉血栓(DVT)的风险各不相同。人们对这种并发症的特征和相关因素知之甚少。本研究旨在:1)研究下肢静脉曲张单独或联合静脉腔内激光消融术(EVLA)进行超声引导下泡沫硬化疗法(UGFS)后深静脉血栓形成的发生率;2)确定与深静脉血栓形成相关的因素。患者和方法:研究对象包括 2011 年至 2015 年期间在苏黎世大学医院接受 UGFS 和 EVLA 或单独接受 UGFS 的所有 18 岁及以上门诊患者。数据提取自医院电子病历。对患者术后的疼痛程度以及对手术的满意度进行了调查。术后7-10天和6-8个月,使用双相超声波对深静脉系统进行评估。回归分析用于研究患者和手术特征与深静脉血栓形成的关系。结果:共纳入 334 名患者(在 393 个不同疗程中进行了 561 次手术):73%的患者接受了UGFS和EVLA联合手术,27%的患者仅接受了UGFS手术。24名患者(7.2%)发生了深静脉血栓,其中88%的患者接受了联合手术,17%的患者在同一次手术中接受了涉及大隐静脉和小隐静脉的介入治疗。8.2%的患者接受了血栓预防措施,9.5%的患者未接受血栓预防措施。女性深静脉血栓发生率为 5.2%,男性为 11.9%。没有发现与干预后诊断为深静脉血栓相关的因素。有深静脉血栓的患者和没有深静脉血栓的患者在疼痛和满意度方面没有差异。结论:这项研究增加了人们对单独进行 UGFS 或联合 EVLA 后深静脉血栓风险的了解。需要进一步研究来修订血栓预防措施。
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Vasa-european Journal of Vascular Medicine
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