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Cystic Adventitial Disease of the Common Femoral Vein Presenting with Lower Limb Swelling: A Case Report. 以下肢肿胀为表现的股总静脉囊性外膜病1例报告。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231165991
Yang Liu, Qiqi Wang, Chunshui He

Cystic adventitial disease (CAD) is a rare vascular disorder predominantly seen in adults without cardiovascular risk factors. We report a case of CAD involving the common femoral vein in a 38-year-old female presented with right lower extremity swelling that was initially misdiagnosed as deep vein thrombosis (DVT). A computed tomography revealed a cystic structure that compressed the right common femoral vein with resultant severe stenosis of the vascular lumen. Complete evacuation of the cyst with excision of the cyst wall was performed, and the patient remained symptom-free at 3 year follow-up. This case highlighted that the rare venous CAD should be incorporated in the differential diagnosis of unilateral lower extremity swelling suspicious for a DVT. Complete evacuation and surgical excision of the cyst often conferred favorable clinical outcome.

囊性外膜病(CAD)是一种罕见的血管疾病,主要见于无心血管危险因素的成年人。我们报告一例累及股总静脉的CAD,患者为38岁女性,表现为右下肢肿胀,最初误诊为深静脉血栓形成(DVT)。计算机断层扫描显示囊性结构压迫右侧股总静脉,导致血管腔严重狭窄。通过切除囊肿壁彻底清除囊肿,患者在3年随访中无症状。本病例强调罕见的静脉性CAD应纳入单侧下肢肿胀疑似深静脉血栓的鉴别诊断。完全清除和手术切除囊肿通常能获得良好的临床结果。
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引用次数: 0
Endovascular Repair of Iatrogenic Inferior Vena Cava and Iliac Vein Injury: A Case Series and Review of the Literature. 医源性下腔静脉和髂静脉损伤的血管内修复:一个病例系列和文献综述。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231163964
Laura Pride, Kierney Jackson, Jonathan Woody, Christopher Everett

Objective: Iatrogenic injury to the large abdominopelvic veins can he highly morbid, and open surgical repair is technically challenging. Endovascular repair with covered stenting across the injured segment offers an alternative to open surgical management. We present a series of patients with operative injury to the inferior vena cava (IVC) and iliac veins who were treated utilizing an endovascular approach and review the available literature on this technique.

Methods: A PubMed keyword and MeSH term search was performed, and titles were reviewed for relevance by the first author. Studies related to endovascular repair of iatrogenic injury to the IVC and iliac veins were then read in detail for possible inclusion in the review. Those deemed appropriate were further analyzed for interventional approach, stent type and size, technical success, post-procedural pharmacologic management, complications and surveillance strategy.

Results: The initial search resulted in 6221 publications. A total of 17 met criteria for inclusion, all of which were case reports or series. Twenty-six patients were described as suffering iatrogenic injury to the IVC or iliac veins, treated with various types and sizes of stents. All cases achieved technical success with hemorrhage control. Procedural complications occurred in 15.4% of cases, including 3 cases of acute thrombus formation and 1 case of stenosis caudal to the initial stent edge requiring additional stenting. Two additional patients experienced stent occlusion in the surveillance period.

Conclusions: Endovascular repair of iatrogenic injury to the IVC and iliac veins can be an effective management option. However, due to limited data regarding this approach, many technical questions remain, including ideal size and type of stent graft, necessity and duration of post-procedural anticoagulant or antiplatelet therapy and appropriate surveillance. Additionally, long term outcomes in this population have not yet been described.

目的:医源性大腹骨盆静脉损伤是一种高度病态的疾病,开放性手术修复在技术上具有挑战性。血管内修复与覆盖支架横跨受伤节段提供了开放手术治疗的另一种选择。我们报告了一系列手术损伤下腔静脉(IVC)和髂静脉的患者,他们采用血管内入路治疗,并回顾了有关该技术的现有文献。方法:进行PubMed关键词和MeSH术语搜索,并由第一作者审查标题的相关性。然后详细阅读与医源性下腔静脉和髂静脉损伤的血管内修复相关的研究,以便可能纳入本综述。这些被认为合适的患者进一步分析介入入路、支架类型和大小、技术成功、术后药理学处理、并发症和监测策略。结果:最初的检索结果为6221篇出版物。共有17份符合纳入标准,均为病例报告或丛书。26例患者被描述为患有医源性下腔静脉或髂静脉损伤,接受各种类型和大小的支架治疗。所有病例均获得出血控制的技术成功。15.4%的病例出现手术并发症,包括3例急性血栓形成和1例初始支架边缘尾侧狭窄需要额外支架置入。另外两名患者在监测期间经历了支架闭塞。结论:腔内修复医源性下腔静脉和髂静脉损伤是一种有效的治疗方法。然而,由于有关该方法的数据有限,许多技术问题仍然存在,包括理想的支架大小和类型,术后抗凝或抗血小板治疗的必要性和持续时间,以及适当的监测。此外,这一人群的长期结果尚未得到描述。
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引用次数: 0
Readmission After COVID-19 for Late Acute Venous Thrombosis; CASE SERIES and Systematic Review of the Literature. 新型冠状病毒感染后晚期急性静脉血栓再入院案例系列与文献系统回顾。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231163976
Oliver Antonio Gómez Gutiérrez, Gabriel Salinas McQuary, Mauricio Gonzalez-Urquijo, Gerardo Lozano Balderas, Mario Alejandro Fabiani

Objective: Assess heterogeneity within patients with resolved COVID-19 to broaden the vision about post-discharge thrombotic cases and postulate possible related mechanisms in search of better anticoagulation guidelines. This study details patients' characteristics, medical history, treatment, and outcomes of readmitted patients with late acute thrombosis through a systematic review of the literature and patients from our academic center database.

Methods: We extracted the records of patients readmitted for venous thrombosis complications after discharge from the database of the first 2000 patients admitted with COVID-19 in our academic center; we also performed a systematic review of the literature using the Medical Subject Headings terms "late thrombosis," "COVID-19," + "venous thrombosis" in PubMed and Google Scholar according to PRISMA guideline.

Results: The literature review found 20 patients suitable for review matching the inclusion criteria. These patients were added to those in our database, summing up a total of 26 patients. The median age was 50 years old, 76.9% were male, and most were overweight or had grade 1 obesity (n = 11, 42.3%). None had a previous thrombotic history, but 50% had an underlying comorbidity. Thrombotic events presented on a median of 20 days (range: 4-150 days) from discharge. Pulmonary embolisms occurred in 23 patients (88.46%), deep vein thrombosis in 4, mesenteric thrombosis, and cerebral venous thrombosis in 1, respectively.

Conclusion: This study found that most patients readmitted for thrombotic events after COVID-19 discharge were middle-aged men with Venous Thrombo Embolism events.

目的:评估已治愈的COVID-19患者的异质性,以拓宽对出院后血栓形成病例的认识,并推测可能的相关机制,以寻求更好的抗凝指南。本研究通过对我们学术中心数据库中的文献和患者的系统回顾,详细介绍了晚期急性血栓患者的特征、病史、治疗和再入院的结果。方法:从我院首2000例新冠肺炎入院患者数据库中提取出院后因静脉血栓形成并发症再入院患者的记录;我们还根据PRISMA指南,在PubMed和Google Scholar中使用医学主题词“晚期血栓形成”、“COVID-19”+“静脉血栓形成”对文献进行了系统回顾。结果:文献综述发现符合纳入标准的患者20例。这些患者被添加到我们的数据库中,总计26例患者。年龄中位数为50岁,76.9%为男性,多数为超重或1级肥胖(n = 11, 42.3%)。没有先前的血栓病史,但50%有潜在的合并症。血栓形成事件出现在出院后20天(范围:4-150天)。肺栓塞23例(88.46%),深静脉血栓4例,肠系膜血栓1例,脑静脉血栓1例。结论:本研究发现,COVID-19出院后因血栓事件再入院的患者以发生静脉血栓栓塞事件的中年男性居多。
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引用次数: 0
Predictors for Distal Revascularization Following Femoral Endarterectomy in Chronic Limb-Threatening Ischemia Patients. 慢性肢体缺血患者股骨动脉内膜切除术后远端血运重建的预测因素。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231154084
Khaled I Alnahhal, Hassan Dehaini, Ahmed A Sorour, Priyam Vyas, Maryana Chumakova, James Bena, Lee Kirksey

Objective: This study aims to identify the clinical variables which are predictive for the benefit of concomitant distal revascularization (DR) to prevent Chronic limb-threatening ischemia (CLTI) progression and the need for major limb amputation.

Methods: This is a retrospective cohort study of patients who presented with lower limb ischemia and required at least femoral endarterectomy (FEA), recruited over a period of 15 years (2002-2016). The patient cohort was divided into three groups based on the type of intervention: A (FEA alone), B (FEA + catheter-based intervention/(CBI)), and C (FEA + surgical bypass (SB)). The primary endpoint was to identify independent predictors for the use of concomitant DR (CBI or SB). Secondary endpoints were amputation rate, length of stay, mortality rate, postoperative ankle-brachial index and complications, readmission rate, re-intervention rate, resolution of symptoms and wound status.

Results: A total of 400 patients were included, 68.0% were males. Most presenting limbs were at Rutherford class (RC) III and WIfI stage 2, with an ankle-brachial index (ABI) of .47 ± .21 and a TASC II class C lesion. No significant differences were found in the primary-assisted and secondary patency rates between the three groups (P > .05, in all). In the multivariate analyses, clinical variables associated with DR were hyperlipidemia (hazard ratio (HR) 2.1-2.2), TASC II D (HR 2.62), Rutherford class 4 (HR 2.3) and 5 (HR 3.7), as well as WIfI stage ≥3 (HR 1.48).

Conclusions: Femoral endarterectomy is sufficient to treat intermittent claudication. However, patients in whom rest pain, tissue loss or TASC II D anatomic lesion severity are present may benefit from concomitant distal revascularization. Taking into consideration the overall assessment of operative risk factors for each individual patient, proceduralists should have a lower threshold for performing early or concomitant distal revascularization to reduce CLTI progression including additional tissue loss and/or major limb amputation.

目的:本研究旨在确定预测伴随远端血运重建术(DR)预防慢性肢体威胁缺血(CLTI)进展和需要截肢的临床变量。方法:这是一项回顾性队列研究,招募了15年(2002-2016)期间出现下肢缺血并至少需要行股动脉内膜切除术(FEA)的患者。根据干预类型将患者队列分为三组:A(单独FEA), B (FEA +导管介入/(CBI))和C (FEA +手术旁路(SB))。主要终点是确定合并DR (CBI或SB)使用的独立预测因子。次要终点为截肢率、住院时间、死亡率、术后踝肱指数和并发症、再入院率、再干预率、症状缓解和伤口状况。结果:共纳入400例患者,男性占68.0%。多数表现为Rutherford (RC) III级和WIfI 2期,踝臂指数(ABI)为0.47±0.21,TASC II C级病变。三组间首次辅助和二次通畅率均无显著差异(P > 0.05)。在多因素分析中,与DR相关的临床变量为高脂血症(风险比(HR) 2.1-2.2)、TASC II D (HR 2.62)、Rutherford 4级(HR 2.3)和5级(HR 3.7),以及WIfI分期≥3 (HR 1.48)。结论:股动脉内膜切除术足以治疗间歇性跛行。然而,存在静息性疼痛、组织丢失或TASCⅱD解剖损伤严重程度的患者可能受益于伴随的远端血运重建术。考虑到对每位患者的手术危险因素的总体评估,手术医生应该有一个较低的阈值来进行早期或伴随的远端血运重建术,以减少CLTI的进展,包括额外的组织损失和/或主要肢体截肢。
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引用次数: 0
N-butyl-2-cyanoacrylate Packing of a Gastroduodenal Artery Pseudoaneurysm due to Distal Pancreatectomy After Subtotal Esophagectomy. 食管大部切除术后胰远端切除术后胃十二指肠动脉假性动脉瘤的n -丁基-2-氰基丙烯酸酯填充。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231165207
Eisuke Shibata, Hidemasa Takao, Osamu Abe

We describe the successful n-butyl cyanoacrylate (NBCA) packing of a large gastroduodenal artery pseudoaneurysm after distal pancreatectomy in a patient with a history of subtotal esophagectomy and gastric tube reconstruction. The pseudoaneurysm was considered to be caused by direct injury to the gastroduodenal artery (GDA). However, embolization of the GDA was not possible in this case because due to prior esophageal surgery, the main blood vessel supplying the gastric tube was the right epigastric artery from the GDA. Packing a pseudoaneurysm with NBCA is a treatment option when preservation of the parent artery is required.

我们描述了一个成功的正丁基氰基丙烯酸酯(NBCA)包装一个大胃十二指肠动脉假性动脉瘤后远端胰腺切除术患者的食管大部切除术和胃管重建的历史。假性动脉瘤被认为是由胃十二指肠动脉(GDA)直接损伤引起的。然而,由于先前的食管手术,供应胃管的主要血管是来自GDA的右腹壁动脉,因此在本例中不可能对GDA进行栓塞。当需要保存载动脉时,用NBCA填充假性动脉瘤是一种治疗选择。
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引用次数: 0
Specialty Balloons for Vessel Preparation During Infrainguinal Endovascular Revascularization Procedures: A Review of Literature. 腹股沟下血管内重建术中用于血管准备的专用球囊:文献综述。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231156077
Stefanos Giannopoulos, Panagiotis Volteas, Dimitrios Virvilis

Balloon angioplasty with/without utilizing drug eluting technology or stenting constitutes the treatment of choice for a significant percentage of patients with peripheral artery disease requiring an intervention. However, in cases of diffuse disease and plaque complexity, angioplasty may lead to dissection, recoil, and/or early restenosis, making vessel preparation a key component for successful and durable endovascular revascularization outcome. This review of literature aims to present contemporary data for several commercially available specialty balloons that have been designed to minimize the arterial wall stress of conventional balloon angioplasty and facilitate technical success, as well as long-term patency.

对于需要干预的外周动脉疾病患者来说,球囊血管成形术(含/不含药物洗脱技术)或支架植入术是治疗的选择。然而,在弥漫性疾病和斑块复杂的情况下,血管成形术可能导致夹层、反冲和/或早期再狭窄,这使得血管准备成为成功和持久的血管内血运重建结果的关键组成部分。这篇文献综述的目的是介绍几种商业上可获得的特殊气球的当代数据,这些气球被设计成最小化传统气球血管成形术的动脉壁应力,促进技术成功,以及长期通畅。
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引用次数: 0
Contrast-Associated Acute Kidney Injury in High-Risk Patients Undergoing Peripheral Vascular Interventions. 接受外周血管介入治疗的高危患者的对比剂相关急性肾损伤
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231162941
Satinderjit Locham, Alejandra Rodriguez, Mark D Balceniuk, Doran Mix, Karina Newhall, Adam Doyle, Roan Glocker, Jennifer Ellis, Michael Stoner

Objective: This study aims to evaluate the use of prophylactic intravenous hydration (IV prophylaxis) and carbon dioxide (CO2) angiography in reducing contrast associated-acute kidney injury (CA-AKI) and determine the overall incidence and risk factors of CA-AKI in high-risk patients undergoing peripheral vascular interventions (PVI). Method: Only patients undergoing elective PVI from 2017 to 2021 with chronic kidney disease (CKD) stage 3-5 in the Vascular Quality Initiative (VQI) database were included. Patients were grouped into IV prophylaxis vs no prophylaxis. The study's primary outcome was CA-AKI, defined as a rise in creatinine (>.5 mg/dL) or new dialysis within 48 hours following contrast administration. Standard univariate and multivariable (logistic regression) analyses were conducted. Results: A total of 4497 patients were identified. Of these, 65% received IV prophylaxis. The overall incidence of CA-AKI was .93%. No significant difference was seen in overall contrast volume (mean (SD): 66.89(49.54) vs 65.94(51.97) milliliters, P > .05) between the 2 groups. After adjusting for significant covariates, the use of IV prophylaxis (OR (95% CI): 1.54(.77-3.18), P = .25) and CO2 angiography (OR (95%CI): .95(.44-2.08), P = .90) was not associated with a significant reduction in CA-AKI compared to the patients with no prophylaxis. The severity of CKD and diabetes were the only predictor of CA-AKI. Compared to patients with no CA-AKI, patients with CA-AKI were at risk of higher 30-day mortality (OR (95% CI): 11.09 (4.25-28.93)) and cardiopulmonary complications (OR (95% CI): 19.03 (8.74-41.39) following PVI (Both P < .001). Conclusion: Using a large national vascular database, our study demonstrates that prophylactic use of IV hydration and CO2 angiography in high-risk CKD patients is not associated with a reduction in renal injury following PVI. Reduced kidney function and history of diabetes is an independent predictor of CA-AKI and patients that develop post-procedural AKI are at an increased risk of morbidity and mortality.

目的:本研究旨在评估预防性静脉补液(IV prolaxis)和二氧化碳(CO2)血管造影在降低造影剂相关急性肾损伤(CA-AKI)中的应用,并确定接受外周血管干预(PVI)的高危患者CA-AKI的总发病率和危险因素。方法:仅纳入血管质量倡议(VQI)数据库中2017年至2021年接受选择性PVI的慢性肾脏疾病(CKD) 3-5期患者。患者分为静脉预防组和不预防组。该研究的主要结局是CA-AKI,定义为肌酐升高(>。5 mg/dL)或在给药后48小时内进行新的透析。进行了标准的单变量和多变量(逻辑回归)分析。结果:共发现4497例患者。其中,65%接受静脉注射预防。CA-AKI的总发生率为0.93%。两组总对比体积(SD均值:66.89(49.54)vs 65.94(51.97) ml, P > 0.05)差异无统计学意义。在调整重要协变量后,与未进行预防的患者相比,静脉预防(OR (95%CI): 1.54(0.77 -3.18), P = 0.25)和CO2血管造影(OR (95%CI): 0.95 (0.44 -2.08), P = 0.90)的使用与CA-AKI的显著降低无关。CKD和糖尿病的严重程度是CA-AKI的唯一预测因子。与无CA-AKI患者相比,CA-AKI患者在PVI后30天死亡率(OR (95% CI): 11.09(4.25-28.93))和心肺并发症(OR (95% CI): 19.03(8.74-41.39)的风险更高(均P < 0.001)。结论:通过一个大型的国家血管数据库,我们的研究表明,高危CKD患者预防性使用静脉水化和CO2血管造影与PVI后肾损伤的减少无关。肾功能降低和糖尿病史是CA-AKI的独立预测因素,术后AKI患者的发病率和死亡率增加。
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引用次数: 0
Spontaneous Iliac Vein Ruptures: A Systematic Review. 自发髂静脉破裂:系统回顾。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231163707
Alexander L Kooiman, Jay M Bakas, Joris M K van Fessem, Willem P A Boellaard, Sandra A P Cornelissen, Marie Josee E van Rijn

Introduction: Spontaneous iliac vein rupture is a rare, but frequently lethal condition. It is important to timely recognize its clinical features and immediately start adequate treatment. We aimed to increase awareness to clinical features, specific diagnostics, and treatment strategies of spontaneous iliac vein rupture by evaluating the current literature.

Methods: A systematic search was conducted in EMBASE, Ovid MEDLINE, Cochrane, Web of Science, and Google Scholar from inception until January 23, 2023, without any restrictions. Two reviewers independently screened for eligibility and selected studies describing a spontaneous iliac vein rupture. Patient characteristics, clinical features, diagnostics, treatment strategies, and survival outcomes were collected from included studies.

Results: We included 76 cases (64 studies) from the literature, mostly presenting with left-sided spontaneous iliac vein rupture (96.1%). Patients were predominantly female (84.2%), had a mean age of 61 years, and frequently presented with a concomitant deep vein thrombosis (DVT) (84.2%). After various follow-up times, 77.6% of the patients survived, either after conservative, endovascular, or open treatment. Endovenous or hybrid procedures were frequently performed if the diagnose was made before treatment, and almost all survived. Open treatment was common if the venous rupture was missed, for some cases leading to death.

Conclusion: Spontaneous iliac vein rupture is rare and easily missed. The diagnose should at least be considered for middle-aged and elderly females presenting with hemorrhagic shock and concomitant left-sided DVT. There are various treatment strategies for spontaneous iliac vein rupture. An early diagnose brings options for endovenous treatment, which seems to have good survival outcomes based on previously described cases.

简介:自发性髂静脉破裂是一种罕见但经常致命的疾病。重要的是要及时认识其临床特征,并立即开始适当的治疗。我们旨在通过评估现有文献,提高对自发性髂静脉破裂的临床特征、具体诊断和治疗策略的认识。方法:系统检索EMBASE、Ovid MEDLINE、Cochrane、Web of Science、Google Scholar数据库,检索时间自成立至2023年1月23日,无任何限制。两名评论者独立筛选了描述自发性髂静脉破裂的研究的资格和选择。从纳入的研究中收集了患者特征、临床特征、诊断、治疗策略和生存结果。结果:我们从文献中纳入76例(64项研究),大多数表现为左侧自发性髂静脉破裂(96.1%)。患者以女性为主(84.2%),平均年龄61岁,常伴有深静脉血栓(DVT)(84.2%)。经过多次随访,77.6%的患者在保守、血管内或开放治疗后存活。如果在治疗前确诊,则经常进行静脉内或混合手术,几乎所有患者都存活了下来。如果错过静脉破裂,开放治疗是常见的,有些病例导致死亡。结论:自发性髂静脉破裂罕见,易漏诊。诊断应至少考虑到中老年女性失血性休克和伴随左侧深静脉血栓。自发性髂静脉破裂的治疗策略多种多样。早期诊断带来了静脉内治疗的选择,根据先前描述的病例,这似乎有良好的生存结果。
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引用次数: 0
Two-Year Results of a First-In-Human Study in Patients Surgically Implanted With a Bioprosthetic Venous Valve, the VenoValve in Patients With Severe Chronic Venous Insufficiency. 一项为期两年的首次人体研究结果,研究对象是外科植入生物假体静脉瓣膜,即严重慢性静脉功能不全患者的静脉瓣膜。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744231155327
Jorge H Ulloa, Sebastian Cifuentes, Valentin Figueroa, Marc Glickman

Objective: Two-year follow-up results from a first-in-human study of patients implanted with the VenoValve are evaluated for supporting the long-term clinical safety and performance of the device.

Background: Chronic Venous Insufficiency (CVI) involves improper functioning of lower limb vein valves and inability of these valves to move blood back towards the heart. CVI symptoms include swelling, varicose veins, pain, and leg ulcers. Currently, there is no cure for this condition and treatment options are limited. This study provides 2-year outcomes for 8 patients who were implanted with the bioprosthetic VenoValve for treating severe CVI with deep venous reflux measured at the mid-popliteal vein. The 6-month and 1-year results were previously published.

Methods: Eleven patients with C5 & C6 CVI were implanted with VenoValve into the midthigh femoral vein and followed for 2 years. Assessed clinical outcomes include device-related adverse events, reflux time, disease severity, and pain scores.

Results: All 11 implant procedures were successful. Two-year follow-up data was obtained for 8 subjects: 1 patient died of non-device related causes, 1 was lost to follow-up, and 1 refused to follow-up due to the COVID-19 pandemic. No device-related adverse events occurred between the first and second years of follow-up. Reported 2-year clinical performance outcomes included significant decreases in mean reflux times of the mid-popliteal vein (61%), and significant improvements in mean scores for disease severity rVCSS (56%) and VAS pain (87%).

Conclusions: Results from this study support long-term safety and effectiveness of the VenoValve for improving CVI severity by reducing reflux and thereby venous pressures in the lower extremities. With limited treatments for valvular incompetence involved in severe, deep venous CVI, the device may be considered as a novel therapy. A pivotal trial in the United States is currently being conducted to assess the device in a larger number of patients.

目的:对首次植入VenoValve患者的2年随访结果进行评估,以支持该设备的长期临床安全性和性能。背景:慢性静脉功能不全(Chronic Venous dysfunction, CVI)是指下肢静脉瓣膜功能不正常,无法将血液运回心脏。CVI症状包括肿胀、静脉曲张、疼痛和腿部溃疡。目前,这种疾病无法治愈,治疗选择也很有限。本研究提供了8例植入生物假体VenoValve治疗严重CVI患者的2年结果,这些患者在腘中静脉处测量了深静脉反流。6个月和1年的结果先前已发表。方法:对11例C5、C6型CVI患者在股中静脉内植入静脉瓣膜,随访2年。评估的临床结果包括器械相关不良事件、反流时间、疾病严重程度和疼痛评分。结果:11例种植均成功。8例受试者获得2年随访资料:1例患者死于非器械相关原因,1例患者失访,1例患者因COVID-19大流行拒绝随访。在第一年和第二年的随访期间没有发生与器械相关的不良事件。报告的2年临床表现结果包括腘中静脉平均反流时间显著减少(61%),rVCSS疾病严重程度平均评分显著改善(56%),VAS疼痛平均评分显著改善(87%)。结论:本研究的结果支持VenoValve通过减少反流从而降低下肢静脉压力来改善CVI严重程度的长期安全性和有效性。由于严重深静脉CVI患者瓣膜功能不全的治疗方法有限,该装置可能被认为是一种新的治疗方法。目前,美国正在进行一项关键试验,以评估该设备在更多患者中的应用。
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引用次数: 0
Duplex-Guided Ipsilateral Antegrade Approach for Flush Superficial Femoral Artery Occlusion. 双导同侧顺行入路治疗股浅动脉阻塞。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-08-01 DOI: 10.1177/15385744221145250
Mahmoud Ismael Saleh, Haitham Ali, Walid M Gamal, Ashraf Gamal Taha

Objective: Recanalization of flush ostial superficial femoral artery (SFA) occlusion is a very challenging procedure. Using the ipsilateral antegrade approach in such lesions has some difficulties. This study aimed to assess the feasibility, efficacy, and outcomes of duplex-guided ipsilateral antegrade access for endovascular treatment of atherosclerotic flush occlusion of the SFA.

Methods: This is a prospective two-center study that included chronic lower extremity ischemia patients with flush occlusion of SFA who underwent duplex-guided ipsilateral antegrade endovascular revascularization due to unfeasible contralateral femoral approach. Flush occlusions were preoperatively documented by duplex ultrasound and computed tomography angiography in all patients. The outcome measures were technical success, patency rates, perioperative morbidity and mortality, limb salvage, and amputation free survival rates.

Results: Between April 2019 and March 2021, 49 patients were enrolled in the current study with a mean age of 63.7 ± 5.7 years. Diabetes was the most common risk factor and was found in 40 (81.6%) patients. Associated popliteal lesions were found in seven (14.3%) patients, while 10 (20.4%) patients had combined tibial disease. Selective stenting was done in nine (18.4%) patients. Technical success was achieved in 43 (87.8%) patients. All failures were due to inability to cross the lesion rather than failure to access the common femoral artery. All complications were minor and occurred in seven (14.3%) patients. Primary, assisted primary, and secondary patency rates were 63.9% ± 7.1%, 82.8% ± 5.6%, and 93.5% ± 3.7% at 12 months, respectively. The overall 12-month limb salvage and amputation free survival rates were 91.8% and 83.3% ± 5.4%, respectively.

Conclusion: Duplex-guided ipsilateral antegrade femoral access is a feasible, safe, and effective endovascular treatment option for flush SFA occlusion when contralateral femoral access is not possible.

目的:冲口股浅动脉闭塞的再通是一项非常具有挑战性的手术。在这类病变中采用同侧顺行入路有一些困难。本研究旨在评估双导同侧顺行通道在血管内治疗SFA动脉粥样硬化性闭塞的可行性、有效性和结果。方法:这是一项前瞻性的双中心研究,包括慢性下肢缺血合并SFA的患者,由于对侧股动脉入路不可行,他们接受了双侧引导的同侧顺行血管内重建术。所有患者术前均通过双超声和计算机断层血管造影记录冲洗闭塞。结果指标为技术成功率、通畅率、围手术期发病率和死亡率、残肢保留率和无截肢生存率。结果:2019年4月至2021年3月,49例患者入组,平均年龄为63.7±5.7岁。糖尿病是最常见的危险因素,有40例(81.6%)患者被发现。伴腘窝病变7例(14.3%),合并胫骨病变10例(20.4%)。选择性支架植入术9例(18.4%)。43例(87.8%)患者技术成功。所有的失败都是由于无法穿过病变,而不是无法进入股总动脉。7例(14.3%)患者发生轻微并发症。12个月时,原发性、辅助原发性和继发性通畅率分别为63.9%±7.1%、82.8%±5.6%和93.5%±3.7%。12个月残肢总存活率为91.8%,无截肢生存率为83.3%±5.4%。结论:双导同侧顺行股骨入路是一种可行、安全、有效的血管内治疗方法,当对侧股骨无法入路时。
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Vascular and Endovascular Surgery
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