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Removal of Migrated Vascular Closure Device Plug Material From the Popliteal Artery Using the Bi-Directional Approach "Push Balloon Into Vessel and Close Embolus From Retrograde Site (PINCER)" Technique: A Case Report. 使用双向入路“将球囊推入血管并从逆行部位闭合栓塞(PINCER)”技术从腘动脉移除可移植血管闭合装置栓塞材料:一例报告。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-04-25 DOI: 10.1177/15385744231173200
Naoki Yoshioka, Yasuhiro Morita, Takahiro Tokuda, Takehiro Yamada, Itsuro Morishima

Vascular closure devices (VCDs) are widely used to achieve rapid hemostasis after percutaneous intervention via the common femoral artery (CFA), with well-established efficacy and safety. Although VCD-related artery occlusion is rare, it can be critical. A 72-year-old female underwent endovascular therapy (EVT) for stent occlusion in the left superficial femoral artery through a 7-Fr guiding sheath from the right CFA. After the procedure, an acute right popliteal artery (POP-A) occlusion, associated with the EXOSEAL VCD plug, occurred. The plug material was successfully removed using a bidirectional approach. The migration plug was blocked to prevent distal vessel migration and pushed gently to close the antegrade system, using an over-the-wire balloon from the retrograde site. We named this the "Push balloon INto vessel and Close Embolus from Retrograde site" (PINCER) technique. Finally, the plug was successfully removed using biopsy forceps. Acute limb ischemia (ALI) caused by EXOSEAL is a rare condition. Removal of the emboli by EVT is clinically significant because it is minimally invasive. However, it is sometimes difficult to remove the embolus using only antegrade approach; thus, the bidirectional approach using the PINCER technique can be effective in these situations.

血管闭合器(VCD)被广泛用于通过股总动脉(CFA)进行经皮介入治疗后实现快速止血,具有公认的疗效和安全性。尽管VCD相关的动脉闭塞是罕见的,但它可能是至关重要的。一名72岁的女性接受了血管内治疗(EVT),通过右侧CFA的7-Fr引导鞘对左股浅动脉进行支架闭塞。手术后,出现急性右腘动脉(POP-A)闭塞,并伴有EXOSEAL VCD栓塞。使用双向方法成功地去除了塞子材料。封堵移行塞以防止远端血管移行,并使用逆行部位的超钢丝球囊轻轻推动以关闭顺行系统。我们将其命名为“将球囊推入血管并从逆行部位闭合栓塞”(PINCER)技术。最后,使用活检钳成功取出塞子。EXOSEAL引起的急性肢体缺血(ALI)是一种罕见的情况。EVT清除栓塞具有临床意义,因为它是微创的。然而,有时仅采用顺行入路切除栓子是困难的;因此,使用PINCER技术的双向方法在这些情况下是有效的。
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引用次数: 0
Superficial Femoral Artery in-Stent Restenosis Treated with Paclitaxel-Coated Balloon Angioplasty - Results of Three-Year Follow-Up. 紫杉醇涂层球囊血管成形术治疗支架再狭窄中的股浅动脉——三年随访结果。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-03-22 DOI: 10.1177/15385744231165877
Julio Cesar Peclat de Oliveira, Rossano Kepler Alvim Fiorelli, Ana Paula Rolim Maia Peclat, Lucas Maia Peclat de Oliveira, Rafael Oliveira, Sergio Quilici Belczac, Renato Santos Almeida, Marcelo Bellini Dalio, Edwaldo Edner Joviliano, Bianca Gutfilen

Background: In-stent restenosis remains a common and important complication after endovascular treatment of superficial femoral artery peripheral artery disease. It occurs in 14 to 35% of cases in 1 year and there is still no efficient treatment for this condition. Paclitaxel-coated balloons have shown promising results.

Objective: Investigate the 3 year results of superficial femoral artery in-stent restenosis treated with paclitaxel-coated balloon angioplasty, using the Lutonix™ 035 device.

Methods: We conducted a retrospective observational study with patients with symptomatic (Rutherford 2 to 5) superficial femoral artery in-stent restenosis, that were treated with paclitaxel-coated balloon angioplasty using the Lutonix™ 035 device, in a single center from January 2016 to December 2020. Duplex scan was used to follow the patients. Primary patency was obtained through Kaplan-Meier analysis. Mortality, and amputation rates were also evaluated.

Results: 105 patients were included. Two patients had technical failure and required an additional stent, and were thus excluded. 103 patients were analyzed. Primary patency was 91.26, 80.47, and 67.71%, respectively, in the first, second, and third year after the procedure. There were no deaths 30 days after the procedure. There were no major amputations during the 3 year follow-up.

Conclusion: Paclitaxel-coated balloon angioplasty with the Lutonix™ 035 device was a safe and effective treatment to superficial femoral artery in-stent restenoses. The results were maintained along the 3 year follow-up.

背景:支架内再狭窄仍然是股浅动脉-外周动脉疾病血管内治疗后常见且重要的并发症。在一年内,14%至35%的病例会发生这种情况,目前还没有有效的治疗方法。紫杉醇涂层气球已经显示出有希望的结果。目的:研究应用紫杉醇涂层球囊血管成形术治疗股浅动脉支架内再狭窄的3年疗效™ 035设备。方法:我们对有症状的(Rutherford 2-5)股浅动脉支架内再狭窄患者进行了一项回顾性观察研究,这些患者使用Lutonix™ 035设备,于2016年1月至2020年12月在单个中心。采用双重扫描对患者进行随访。主要通畅性通过Kaplan-Meier分析获得。死亡率和截肢率也进行了评估。结果:纳入105例患者。两名患者出现技术故障,需要额外的支架,因此被排除在外。对103例患者进行了分析。术后第一年、第二年和第三年的初次通畅率分别为91.26%、80.47%和67.71%。术后30天无死亡病例。在3年的随访中并没有发生大的截肢。结论:紫杉醇涂层的Lutonix球囊血管成形术™ 035装置是一种安全有效的治疗股浅动脉支架置入术的方法。结果在3年的随访中得以维持。
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引用次数: 0
Comparison of Radiofrequency Ablation and Saphenous Vein Stripping for the Treatment of Recurrent Lower Extremity Venous Insufficiency. 射频消融与隐静脉剥离治疗复发性下肢静脉功能不全的比较。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-04-26 DOI: 10.1177/15385744231173192
Eyup Murat Kanber, Hakkı Kursat Cetin

Objective: To compare the efficiency and safety of radiofrequency ablation (RFA) and saphenous vein stripping (SVS) for the treatment of recurrent lower extremity chronic superficial venous insufficiency (CSVI).

Methods: Patients who underwent SVS and RFA for recurrent lower extremity CSVI following RFA and patients who had 2-year follow-up results were enrolled into the study. Total, 37 patients who underwent a second RFA session with 2-year follow-up results were available. Then 37 patients were selected from 88 patients who underwent SVS for recurrent lower extremity CSVI to achieve a 1:1 ratio for comparison. Groups were compared based on preoperative properties, operative parameters, postoperative outcomes, complications and follow-up results.

Results: Duration of the procedure was 20.7 minutes in the RFA group and 30.7 minutes in the SVS group (P = .001). Postoperative pain at first hour, sixth hour and 24th hour were significantly lower in patients who underwent RF (P = .001 for each parameter). Moreover, hospitalization time (18.1 hours vs 24.6 hours, P = .001) and time to return to normal daily activities (1.6 days and 2.5 days, P = .001) were significantly shorter in the RFA group. Success of the procedure did not statistically significant at first year follow-up (P = .304). However, success was significantly higher for the SVS group at second year follow-up (73% for RFA group and 91.9% for SVS group, P = .032).

Conclusion: We achieved significantly shorter procedure time, less postoperative hospitalization time, and a shorter time to return to daily activities with RFA. In contrast, the success rate of SVS was significantly higher at the second year follow-up, but not the first year follow-up in comparison with RFA.

目的:比较射频消融术(RFA)和隐静脉剥离术(SVS)治疗复发性下肢慢性浅静脉功能不全(CSVI)的有效性和安全性。总共有37名患者接受了第二次RFA治疗,并获得了2年的随访结果。然后从88名接受SVS治疗复发性下肢CSVI的患者中选择37名患者,以达到1:1的比例进行比较。根据术前特点、手术参数、术后结果、并发症和随访结果对各组进行比较。结果:RFA组和SVS组的手术持续时间分别为20.7分钟和30.7分钟(P=0.001)。接受RF的患者术后第一小时、第六小时和第二十四小时的疼痛显著降低(每个参数P=0.001)。此外,RFA组的住院时间(18.1小时vs 24.6小时,P=.001)和恢复正常日常活动的时间(1.6天和2.5天,P=0.001)显著缩短。在第一年随访时,该手术的成功率没有统计学意义(P=.304)。然而,SVS组在第二年随访时的成功率明显更高(RFA组为73%,SVS小组为91.9%,P=.032)。结论:RFA显著缩短了手术时间,减少了术后住院时间,缩短了恢复日常活动的时间。相反,与RFA相比,SVS的成功率在第二年随访时显著较高,但在第一年随访时没有。
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引用次数: 0
Re-Rupture 2 Years after Endovascular Aortic Aneurysm Repair Rupture. 血管内主动脉瘤修复破裂2年后再次破裂。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-03-24 DOI: 10.1177/15385744231166797
Konstantinos G Moulakakis, Andreas Tsimpoukis, Konstantinos Katsanos, Eleni Sintou, Spyros Papadoulas

Re-rupture 2 years after endovascular aortic aneurysm repair (EVAR) rupture is an extremely rare event and limited data exist in the literature. We present an interesting case of a patient with an abdominal aortic rupture that had undergone 2 years before an endovascular repair for rupture after EVAR due to a type IA endoleak. The patient underwent a successful embolization of the type IA endoleak. Onyx was used to seal the gutter between the aortic wall and the endograft and the 1-month post-embolization CT showed complete sealing with no contrast in the sac. Two years after the rupture, he was presented again with clinical signs of hemodynamic shock and instability. An urgent CT Angiograph showed again rupture due to a type IA endoleak. The patient underwent an emergency open laparotomy. We analyze the re-rupture after EVAR while taking data from the literature into account.

血管内主动脉瘤修复术(EVAR)破裂后2年再次破裂是一种极为罕见的事件,文献中的数据有限。我们介绍了一个有趣的病例,一名腹主动脉破裂的患者在因IA型内漏而进行EVAR后破裂的血管内修复前接受了2年的治疗。患者接受了IA型内漏的成功栓塞治疗。玛瑙用于密封主动脉壁和内移植物之间的沟槽,栓塞后1个月的CT显示完全密封,囊中没有造影剂。破裂两年后,他再次出现血液动力学休克和不稳定的临床症状。紧急CT血管造影显示IA型内漏再次破裂。病人接受了紧急剖腹手术。我们分析了EVAR后的再破裂,同时考虑了文献中的数据。
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引用次数: 0
Mycotic Abdominal Aortic Aneurysm Secondary to BCG Therapy for Non-muscle Invasive Urothelial Carcinoma of the Bladder. BCG治疗非肌肉浸润性膀胱尿路上皮癌继发的真菌性腹主动脉瘤。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-04-18 DOI: 10.1177/15385744231171754
Levi Godard, Linda Lee, Brandon McGuinness, Hemlata Shirsat, Nathan Hoag
Bacillus Calmette-Guerin (BCG) therapy for treatment of bladder cancer is a rare cause of Mycobacterium bovis infected aortic aneurysm. Typical presentations have included general malaise, fever, and lower back pain. We present a case with lower back pain and constipation as presenting symptoms, leading to diagnosis of mycotic aneurysm presumed secondary to intravesical BCG therapy. Treatment included open surgical repair with femoral vein grafting and anti-tubercular therapy. This case highlights the importance of a high index of suspicion for less common infectious complications of BCG therapy.
Calmette-Guerin(BCG)治疗膀胱癌症是牛分枝杆菌感染主动脉瘤的罕见原因。典型的表现包括全身不适、发烧和下背痛。我们报告了一例以下背痛和便秘为症状的病例,从而诊断为真菌性动脉瘤,推测其继发于膀胱内BCG治疗。治疗包括股静脉移植开放性外科修复和抗结核治疗。该病例强调了对BCG治疗不太常见的感染性并发症的高怀疑指数的重要性。
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引用次数: 0
Resection of Extrapulmonary Lymphangiomyoma and Post-Operative Management Considerations. 肺外淋巴管肌瘤的切除及术后处理注意事项。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-03-23 DOI: 10.1177/15385744221144503
Roi Abramov, Liel Rufizen, Hayim Gilshtein

Background: Lymphangiomyomatosis is a rare disease involving the lymph vessels, causing obstruction and cystic formation with an incidence of 3-8 per million women. The disease might be sporadic or inherited. Lymphangiomyomatosis mostly affects the pulmonary system, whereas extrapulmonary Lymphangiomyomatosis may present in various site, occasionally as a localized abdominal mass. The diagnostic process might entail surgical resection to obtain a specimen for pathology that may also help to achieve a long-term control of the disease. Methods: Herein, we present a case of a 45 years old female, who suffered from pulmonary symptoms, and during her workup an abdominal mass was found. The patient underwent exploratory laparotomy with resection of a left retroperitoneal bilobar mass. Results: Histopathological report revealed Lymphangiomyoma. She had a complication of a lymphatic leakage that required a second laparotomy with satisfactory clinical outcome. Conclusions: Surgeons should be aware of the pathological lymphatics and manage post-operative complications by a trial of conservative.

背景:淋巴管瘤病是一种罕见的涉及淋巴管的疾病,可导致梗阻和囊性形成,发病率为3-8/百万女性。这种疾病可能是散发性的,也可能是遗传性的。淋巴管肌瘤病主要影响肺部系统,而肺外淋巴管肌瘤症可能出现在不同的部位,偶尔表现为局限性腹部肿块。诊断过程可能需要手术切除,以获得病理标本,这也可能有助于实现疾病的长期控制。方法:我们报告一例45岁女性,她患有肺部症状,在检查过程中发现腹部肿块。患者接受了剖腹探查术,切除了左腹膜后双叶肿块。结果:组织病理学报告显示淋巴管肌瘤。她有淋巴管渗漏的并发症,需要进行第二次剖腹手术,临床结果令人满意。结论:外科医生应了解病理性淋巴管,并通过保守试验来处理术后并发症。
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引用次数: 0
Emergent Total Endovascular Arch Repair for Contained Aortic Arch Rupture: Another Tool in the Box. 急诊全血管内主动脉弓修复术治疗主动脉弓破裂:另一种工具。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-04-14 DOI: 10.1177/15385744231170919
Nicole Kus, Justin A Robinson, Michael R Hall, Mehrdad Ghoreishi, Bradley Taylor, Shahab Toursavadkohi

To date, emergent total endovascular aortic arch repair has not been described in the literature. We present a 67-year-old female with a poorly differentiated posterior mediastinal sarcoma. Imaging obtained was concerning for intravascular extension of the tumor into the thoracic aorta. While awaiting radiation therapy, the patient complained of worsening chest and arm pain, vital signs demonstrating tachypnea and hypoxia. Subsequent imaging revealed an increase in vascular erosion, concerning for a contained rupture, with complete obliteration of the left mainstem bronchus. The patient was emergently taken for percutaneous endovascular repair of her aortic arch. A three-vessel physician modified fenestrated graft was created and deployed with concurrent stenting of the innominate, left carotid, and left subclavian arteries. Interval computed tomography angiography revealed patency in all stented vessels, with no endoleak and no evidence of pseudoaneurysm. The patient was able to undergo chemotherapy with favorable decrease in tumor burden. Total endovascular aortic arch repair, when planned carefully, is an attractive option in high-risk patients who are otherwise not ideally suited for open total arch replacement.

到目前为止,文献中还没有描述紧急的全血管内主动脉弓修复术。我们报告一位67岁的女性,患有低分化的后纵隔肉瘤。所获得的影像学是关于肿瘤血管内延伸到胸主动脉。在等待放射治疗期间,患者抱怨胸部和手臂疼痛加剧,生命体征显示呼吸急促和缺氧。随后的影像学检查显示,血管侵蚀增加,涉及可控破裂,左主干支气管完全闭塞。患者被紧急送往经皮腔内修复主动脉弓。创建并部署了一个三血管医师改良的开窗移植物,同时对无名动脉、左颈动脉和左锁骨下动脉进行支架植入。计算机断层扫描血管造影术显示所有支架血管通畅,无内漏,也无假性动脉瘤的迹象。该患者能够接受化疗,肿瘤负担明显减轻。如果仔细计划,全血管内主动脉弓修复对高危患者来说是一个有吸引力的选择,否则这些患者不适合进行开放式全弓置换术。
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引用次数: 1
Randomized clinical Trial Comparing drug Eluting Stent Zilver PTX® Versus Bare Metal Stent Zilver Flex® for Treatment of Lesions in Femoral and Popliteal Arteries in Chronic Limb Threatening Ischemia. 比较药物洗脱支架Zilver PTX®与裸金属支架Zilver-Flex®治疗慢性肢体威胁性缺血中股动脉和腘动脉病变的随机临床试验。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-04-21 DOI: 10.1177/15385744231171746
Torbjörn Fransson, Anders Gottsäter, Mohammad Abdulrasak, Martin Malina, Timothy Resch

Objective: Drug eluting stents (DES) might improve the results of stenting in the femoropopliteal (FP) segment, but randomized data between DES and BMS in the treatment of patients with chronic limb threatening ischemia (CLTI) is lacking. The aim of this study was to perform a randomized comparison, between DES and bare metal stent (BMS) implantation in a subgroup of CLTI patients with lesions in the superficial femoral artery (SFA) and the P1-P2 portion of the popliteal artery.

Methods: Patients presenting with CLTI scheduled for endovascular treatment of FP lesions were randomly assigned by blinded envelopes 1:1 in a single blinded, parallel group design to DES or BMS after lesion crossing. Primary endpoints were target lesion revascularization (TLR) at 12 and 24 months and primary patency at 12 and 24 months. Secondary endpoints were technical success (TS), clinical success, secondary patency at 12 and 24 months, limb salvage, serious adverse events (SAE) at 24 month and survival at five years.

Results: A total of 48 CLTI patients and 49 limbs, were enrolled, 22 in the BMS group and 27 in the DES group. Demographics, comorbidities, and Rutherford class were similar in both treatment arms. The overall rate of total occlusions was 96% and the corresponding overall median lesion length was 240 mm. No patients were lost to follow up. No significant differences were detected between groups regarding TLR and primary patency. The overall primary patency at 12 and 24 months was 42.9% and 36.7% respectively and the overall freedom from TLR was 67.3% and 61.2% respectively. The results in the two groups were also similar regarding secondary outcomes.

Conclusions: This single centre, randomized study could not demonstrate superiority of DES compared to BMS when treating long FP lesions in patients with CLTI but was limited by insufficient patient inclusion.

目的:药物洗脱支架(DES)可以改善股腘段支架植入术的效果,但缺乏DES和BMS治疗慢性肢体威胁性缺血(CLTI)患者的随机数据。本研究的目的是在股浅动脉(SFA)和腘动脉P1-P2部分有病变的CLTI患者亚组中,对DES和裸金属支架(BMS)植入进行随机比较。方法:将计划进行FP病变血管内治疗的CLTI患者通过单盲、平行组设计中的盲信封1:1随机分配到病变交叉后的DES或BMS。主要终点为12个月和24个月时的靶病变血运重建(TLR)以及12个月至24个月的主要通畅性。次要终点为技术成功率(TS)、临床成功率、12个月和24个月的次要通畅率、肢体挽救率、24个月严重不良事件(SAE)和5年生存率。结果:共有48名CLTI患者和49条肢体入选,其中22例在BMS组,27例在DES组。两个治疗组的人口学、合并症和Rutherford分类相似。总闭塞率为96%,相应的总中位病变长度为240mm。没有患者失访。两组之间在TLR和初次通畅性方面没有发现显著差异。12个月和24个月时的总体初次通畅率分别为42.9%和36.7%,TLR的总体自由度分别为67.3%和61.2%。两组的次要结果也相似。结论:这项单中心随机研究在治疗CLTI患者的长FP病变时,不能证明DES与BMS相比的优越性,但受患者纳入不足的限制。
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引用次数: 0
Hepatic Arterioportal Fistula Following Liver Trauma: Case Series and Review of the Literature. 肝损伤后肝动脉门瘘:病例系列和文献复习。
IF 0.7 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-03-20 DOI: 10.1177/15385744231165155
Soroosh Noorbakhsh, Lissette Gomez, Yoo Joung, Courtney Meyer, Dustin S Hanos, Mari Freedberg, Nathan Klingensmith, April A Grant, Deepika Koganti, Jonathan Nguyen, Randi N Smith, Jason D Sciarretta

Purpose: Hepatic arterioportal fistula (HAPF) is an uncommon complication of hepatic trauma, which can manifest with abdominal pain and the sequelae of portal hypertension months to years after injury. The purpose of this study is to present cases of HAPF from our busy urban trauma center and make recommendations for management.

Methods: One hundred and twenty-seven patients with high-grade penetrating liver injuries (American Association for the Surgery of Trauma [AAST] - Grades IV-V) between January 2019 and October 2022 were retrospectively reviewed. Five patients were identified with an acute hepatic arterioportal fistula following abdominal trauma from our ACS-verified adult Level 1 trauma center. Institutional experience with overall surgical management is described and reviewed with the current literature.

Results: Four of our patients presented in hemorrhagic shock requiring emergent operative intervention. The first patient had postoperative angiography and coil embolization of the HAPF. Patients 2 through 4 underwent damage control laparotomy with temporary abdominal closure followed by postoperative transarterial embolization with gelatin sponge particles (Gelfoam) or combined Gelfoam/n-butyl cyanoacrylate. The final patient went directly for angiography and Gelfoam embolization after identification of the HAPF. All 5 patients had resolution of HAPF on follow-up imaging with continued post management for traumatic injuries.

Conclusion: Hepatic arterioportal fistula can present as a complication of hepatic injury and manifest with significant hemodynamic aberrations. Although surgical intervention was required to achieve hemorrhage control in almost all cases, management of HAPF in the setting of high-grade liver injuries was achieved successfully with modern endovascular techniques. A multidisciplinary approach to such injuries is necessary to optimize care in the acute setting following traumatic injury.

目的:肝动脉门静脉瘘(HAPF)是肝损伤的一种罕见并发症,可表现为损伤后数月至数年的腹痛和门静脉高压后遗症。本研究的目的是介绍我们繁忙的城市创伤中心的HAPF病例,并提出管理建议。方法:回顾性分析2019年1月至2022年10月期间127例高级穿透性肝损伤(美国创伤外科协会[AAST]-IV-V级)患者。我们的ACS验证的成人1级创伤中心有5名患者在腹部创伤后发现了急性肝动脉门静脉瘘。对整体外科手术管理的机构经验进行了描述,并结合当前文献进行了回顾。结果:4例患者出现失血性休克,需要紧急手术干预。第一例患者行HAPF术后血管造影术和线圈栓塞。2至4名患者接受了损伤控制的剖腹手术,暂时关闭腹部,然后在术后用明胶海绵颗粒(Gelfoam)或Gelfoam/氰基丙烯酸正丁酯联合动脉栓塞。最后一位患者在确认HAPF后直接进行血管造影术和明胶海绵栓塞。所有5名患者在后续影像学检查中均获得了HAPF的分辨率,并在创伤后继续治疗。结论:肝动静脉瘘是肝损伤的一种并发症,表现为明显的血液动力学异常。尽管几乎所有病例都需要手术干预来控制出血,但在高级别肝损伤的情况下,HAPF的管理是通过现代血管内技术成功实现的。有必要对此类损伤采取多学科方法,以优化创伤后急性环境中的护理。
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引用次数: 0
Amputation of the Unsalvageable Leg in Vascular Patients with Cancer. 癌症血管性患者不可挽救腿的截肢。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-10-01 Epub Date: 2023-04-18 DOI: 10.1177/15385744231171752
Arsalan Wafi, Vijay Kolli, Bilal Azhar, Grace Poole, James Budge, Paul Moxey, Ian Loftus, Peter Holt

Objectives: The aim of this study was to compare outcomes of major lower limb amputation (MLA) in patients with and without cancer and with cancer patients receiving palliation over amputation for their unsalvageable limb.

Methods: Cancer patients who underwent a major amputation or palliation between 2013 and 2018 were included. Comparison groups were cancer-MLA (active/managed cancers), non-cancer MLA (historic cancer or no cancer history) and cancer-palliation at presentation with unsalvageable limbs. Prospectively collected data was retrospectively analysed for outcomes including survival, postoperative complications, length of stay, suitability for rehabilitation and discharge destination.

Results: 262 (cancer and non-cancer) patients underwent MLA and 18 patients with cancer received palliation. Of those amputated, 26 (9.9%) had active or managed cancer, of which 12 were diagnosed in the 6 months before MLA. Cancer-MLA patients presented with more acute ischaemia compared to non-cancer patients. Median survival was significantly different between the cancer-MLA (14.1 [9.5 - 29.5, 95% CI] months), non-cancer MLA (57.7 [45 - 73.6, 95% CI] months) and cancer-palliation (.6 [.4 - 2.3, 95% CI] months) groups, P < .001. A significantly higher proportion of cancer-MLA patients (10/26, 38.5%) were deemed unsuitable for rehabilitation in post-operative assessment compared to non-cancer MLA (21/236, 8.9%) patients, P < .001. There was a variation in destinations of discharge, with a greater proportion of cancer-MLA patients (4/26, 15.4%) going to a nursing home compared to non-cancer MLA (10/236, 4.2%) patients, P = .016.

Conclusion: Cancer is prevalent among vascular amputees, with a large proportion being occult diagnoses. Cancer is associated with poorer outcomes following amputation, but survival remains significantly better compared to palliation in cancer patients presenting with unsalvageable limbs.

目的:本研究的目的是比较癌症患者和非癌症患者的主要下肢截肢(MLA)的结果,以及癌症患者因无法修复的肢体而接受截肢缓解的结果。方法:纳入2013年至2018年间接受重大截肢或姑息治疗的癌症患者。对照组为癌症-MLA(活动性/管理性癌症)、非癌症MLA(历史性癌症或无癌症史)和出现四肢不可修复的癌症。前瞻性收集的数据进行了回顾性分析,包括生存率、术后并发症、住院时间、是否适合康复和出院目的地。结果:262例癌症和非癌症患者接受了MLA,18例癌症患者接受了缓解。在被截肢的患者中,26人(9.9%)患有活动性或治疗性癌症,其中12人是在MLA前6个月被诊断的。与非癌症患者相比,癌症-MLA患者表现出更多的急性缺血。癌症-MLA组(14.1个月[9.5-29.5个月,95%CI])、非癌症MLA组(57.7个月[45-73.6个月,95%CI]个月)和癌症伴癌组(.6个月[4-2.3个月,95%CI])的中位生存率有显著差异,P<.001。与非癌症MLA患者(21/236,8.9%)相比,癌症-MLA患者(10/26,38.5%)在术后评估中被认为不适合康复的比例显著更高,P<.001。出院目的地存在差异,癌症-MLA患者(4/26,15.4%)前往疗养院的比例高于非癌症MLA患者(10/236,4.2%),P=0.016。结论:癌症在血管截肢者中普遍存在,其中很大一部分是隐性诊断。癌症与截肢后的不良后果相关,但与肢体无法修复的癌症患者的缓解相比,存活率仍然显著提高。
{"title":"Amputation of the Unsalvageable Leg in Vascular Patients with Cancer.","authors":"Arsalan Wafi,&nbsp;Vijay Kolli,&nbsp;Bilal Azhar,&nbsp;Grace Poole,&nbsp;James Budge,&nbsp;Paul Moxey,&nbsp;Ian Loftus,&nbsp;Peter Holt","doi":"10.1177/15385744231171752","DOIUrl":"10.1177/15385744231171752","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to compare outcomes of major lower limb amputation (MLA) in patients with and without cancer and with cancer patients receiving palliation over amputation for their unsalvageable limb.</p><p><strong>Methods: </strong>Cancer patients who underwent a major amputation or palliation between 2013 and 2018 were included. Comparison groups were cancer-MLA (active/managed cancers), non-cancer MLA (historic cancer or no cancer history) and cancer-palliation at presentation with unsalvageable limbs. Prospectively collected data was retrospectively analysed for outcomes including survival, postoperative complications, length of stay, suitability for rehabilitation and discharge destination.</p><p><strong>Results: </strong>262 (cancer and non-cancer) patients underwent MLA and 18 patients with cancer received palliation. Of those amputated, 26 (9.9%) had active or managed cancer, of which 12 were diagnosed in the 6 months before MLA. Cancer-MLA patients presented with more acute ischaemia compared to non-cancer patients. Median survival was significantly different between the cancer-MLA (14.1 [9.5 - 29.5, 95% CI] months), non-cancer MLA (57.7 [45 - 73.6, 95% CI] months) and cancer-palliation (.6 [.4 - 2.3, 95% CI] months) groups, P < .001. A significantly higher proportion of cancer-MLA patients (10/26, 38.5%) were deemed unsuitable for rehabilitation in post-operative assessment compared to non-cancer MLA (21/236, 8.9%) patients, P < .001. There was a variation in destinations of discharge, with a greater proportion of cancer-MLA patients (4/26, 15.4%) going to a nursing home compared to non-cancer MLA (10/236, 4.2%) patients, P = .016.</p><p><strong>Conclusion: </strong>Cancer is prevalent among vascular amputees, with a large proportion being occult diagnoses. Cancer is associated with poorer outcomes following amputation, but survival remains significantly better compared to palliation in cancer patients presenting with unsalvageable limbs.</p>","PeriodicalId":23530,"journal":{"name":"Vascular and Endovascular Surgery","volume":" ","pages":"697-705"},"PeriodicalIF":0.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9673692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Vascular and Endovascular Surgery
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