Wound management & prevention最新文献_第7页

Negative pressure wound therapy with instillation in lower extremity wounds may contribute to cost-savings: 4 case reports. 在下肢伤口中滴注负压伤口治疗有助于节省费用：4例报告。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-05-01 DOI: 10.25270/wmp.2023.2.22058

R. Napolitano

BACKGROUNDUse of negative pressure wound therapy with instillation and dwell time (NPWTi-d) can assist with wound bed preparation for successful closure. The authors present their experience using NPWTi-d to manage lower extremity wounds in 4 patients and discuss the feasibility of improving cost efficiency.METHODSNPWTi-d involved instillation of normal saline with an 8-to 10 minute dwell time, followed by 3 to 3.5 hours of -125 mm Hg. Therapy continued for 6 to 7 days with dressing changes every 2 to 3 days.RESULTSPatients were all male, between the ages of 24 and 83 years old. Wound etiologies included chemical burn, deep tissue laceration, compartment syndrome with hematoma, and diabetic foot osteomyelitis. All wounds required cleansing. Prior to NPWTi-d, surgical debridement and antibiotics were administered as necessary. After NPWTi-d, the wounds exhibited healthy granulation and reduced in size, allowing for discharge to outpatient care. Upon follow-up 2 to 6 months later, no patients experienced wound complications or required readmission to the operating room, potentially saving on time and cost.CONCLUSIONIn these patients, use of NPWTi-d assisted in cleansing the wound surface and producing a positive healing outcome. Despite higher initial costs of NPWTi-d over standard dressings, a wound management protocol including NPWTi-d may help mitigate expenses incurred by delayed healing.

背景使用负压伤口治疗加滴注和停留时间（NPWTi-d）可以帮助伤口床为成功闭合做准备。作者介绍了他们使用NPWTi-d治疗4例下肢创伤的经验，并讨论了提高成本效益的可行性。方法滴注生理盐水，停留时间8至10分钟，然后滴注3至3.5小时-125毫米汞柱。治疗持续6至7天，每2至3天更换一次敷料。结果患者均为男性，年龄在24-83岁之间。伤口病因包括化学烧伤、深部组织撕裂伤、隔室综合征伴血肿和糖尿病足骨髓炎。所有伤口都需要清洗。在NPWTi-d之前，根据需要进行外科清创术和使用抗生素。NPWTi-d后，伤口表现出健康的肉芽并缩小，可以出院到门诊护理。在2至6个月后的随访中，没有患者出现伤口并发症或需要再次进入手术室，这可能节省了时间和成本。结论在这些患者中，使用NPWTi-d有助于清洁伤口表面，并产生积极的愈合效果。尽管NPWTi-d的初始成本高于标准敷料，但包括NPWTi-d在内的伤口管理方案可能有助于减轻延迟愈合所产生的费用。

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引用次数: 0

Textile composition, not number of layers, impacts interphase pressure and static stiffness index: A pragmatic, comparative analysis of the in vivo interphase pressure of 7 different 2-layer cohesive bandage kits in healthy volunteers. 纺织成分，而不是层数，影响间期压力和静态刚度指数:7种不同的2层粘结性绷带包在健康志愿者体内的间期压力的实用对比分析。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-05-01 DOI: 10.25270/wmp.2023.2.22072

S. Ehmann, Albert E. Ortega, H. Hettrick

"OBJECTIVE: The aim of the study was to comparatively evaluate the in vivo interphase pressure (IP) and statis stiffness index (SSI), upon initial application, of 7, 2-layer cohesive bandage kits when applied on healthy volunteers.METHODBandages were applied in random order, on non-consecutive days by a single experienced clinician. The IP at the time of application was measured on the right lower limb of 10 healthy volunteers at 2 different points (B1, C). Measurements were made in 2 positions, supine and standing. There were 2 consecutive applications and measurements made for each compression bandage set. Statistical analysis of the outcome data was performed, utilizing a repeated measures analysis of variance (ANOVA) to determine: the effects of the bandage type on IP and SSI for each of the measurement points and according to the subject's position. Post hoc analyses were performed by Tukey and Bonferroni test to identify significant differences. The dispersion of the recorded pressures within the study population (dispersion between subjects) was assessed by the coefficient of variations.RESULTSThe in vivo IP measured at B1 in the supine position varied from 50.1 mmHg (±5.3) to 73.7 mmHg (±13.4). The in vivo IP measured at C in the supine position varied from 53.2 mmHg (±7.6) to 69.3 mmHg (±10.6). Bonferroni post hoc analyses demonstrated with a 95% confidence interval, there was a significant difference between wraps and placed them into 5 groups for the IP measured at B1, and 3 groups for measurements taken at C. A regression model including the main effects of the wrap and the subject with their interaction were similar for the IP observed at B1 and C in the supine position (r2 = 0.881). The in vivo SSI measured at B1 varied from 11.95 (±5.4) to 6.65 (±4.4). Post hoc analyses similarly demonstrated significant differences placing the wraps into 3 different groups. Statistical analysis of the variability of the IP observed at B1 and C showed there was a significant difference at B1 (P = .001), which was not observed at C (P = .347).CONCLUSIONSub-bandage pressure measurements produced by the 7, '2-layer cohesive' compression box sets were not equivocal. IP and SSI varied by textile composition, clinically supporting the trial of alternative '2-layer cohesive' compression box set if the desired outcome (ie, wound healing, edema reduction) is not achieved. Additional study in patients with edema is warranted to allow an evidenced-based approached to the selection of a compression bandage set.

目的：本研究的目的是比较评估体内相间压（IP）和统计硬度指数（SSI）初次使用时，在健康志愿者身上使用7，2层粘性绷带包。方法由一名经验丰富的临床医生在非连续的几天内随机使用绷带。在2个不同点（B1、C）对10名健康志愿者的右下肢测量应用时的IP。测量采用仰卧和站立两种姿势。对每个压缩绷带组进行2次连续应用和测量。利用重复测量方差分析（ANOVA）对结果数据进行统计分析，以确定绷带类型对每个测量点的IP和SSI的影响，并根据受试者的位置。通过Tukey和Bonferroni检验进行事后分析，以确定显著差异。记录的压力在研究人群中的分散性（受试者之间的分散性）通过变异系数进行评估。结果仰卧位B1处测得的体内IP在50.1 mmHg（±5.3）至73.7 mmHg（？3.4）之间变化。仰卧位C处测得体内IP在53.2 mmHg（士7.6）至69.3 mmHg（徒10.6）之间变化，和3组用于在C。包括包裹物和受试者的主要影响及其相互作用的回归模型在仰卧位B1和C处观察到的IP相似（r2=0.881）。在B1处测量到的体内SSI在11.95（±5.4）到6.65（±4.4）之间变化。事后分析同样表明，将包裹物分为3组存在显著差异。对B1和C处观察到的IP变异性的统计分析显示，B1处存在显著差异（P=0.001），而C处没有观察到（P=.347）。结论7个“2层粘性”压缩盒组产生的子绷带压力测量结果并非模棱两可。IP和SSI因织物成分而异，临床上支持在未达到预期结果（即伤口愈合、水肿减轻）的情况下进行替代性“2层粘性”压缩箱定型试验。有必要对水肿患者进行额外的研究，以便对压缩绷带的选择进行基于证据的方法。

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引用次数: 0

Therapeutic modalities of human β defensin-2 with prospective significance in diabetic wound treatment. 人β防御素-2治疗方式在糖尿病创面治疗中的前瞻性意义。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-05-01 DOI: 10.25270/wmp.2023.2.22084

Vidyasrilekha. Yele, Bharat Kr Sanapalli

BACKGROUNDDiabetic Wounds (DW) are a debilitating complication of diabetes. Although various therapeutic strategies are available for DW management, none of them meet all the fundamentals due to the multifaceted pathophysiology of DW. Given the ever-present threat of DW, novel improved therapeutic strategies and the fortification of DW research deserve better prioritization.PURPOSEThe current review aims to provide the detailed role of human β defensin-2 (HBD-2) in skin wounds with a prospective significance in DW treatment.METHODSThis review was conducted through searches of relevant abstracts, research and review articles, and patents, in Scopus, Web of Science, PubMed, Google Scholar, and Clinical Trials databases of English language articles.RESULTSHBD-2 is a critical innate immune-response protein that defends the human body from infections. Recent reports also support the role of HBD-2 in suppressing inflammation and promoting proliferation and angiogenesis. Based on the literature, its therapeutic administration has been proposed to maintain the equilibrium of systemic homeostasis in DW.CONCLUSIONIt has been hypothesized that HBD-2 could be a crucial modulator for controlling chronic inflammation and size by promoting proliferation and angiogenesis, opening up new therapy options in DW.

背景:糖尿病伤口(DW)是糖尿病的一种使人衰弱的并发症。虽然有多种治疗策略可用于DW的治疗，但由于DW的病理生理多方位，没有一种治疗策略能满足所有的基本要求。鉴于DW一直存在的威胁，新的改进的治疗策略和DW研究的加强应该得到更好的优先考虑。目的研究人β防御素-2 (HBD-2)在皮肤创面中的作用，为DW治疗提供参考。方法在Scopus、Web of Science、PubMed、谷歌Scholar和Clinical Trials英文论文数据库中检索相关摘要、研究综述文章和专利。结果shbd -2是一种保护人体免受感染的重要先天免疫反应蛋白。最近的报道也支持HBD-2在抑制炎症、促进增殖和血管生成方面的作用。根据文献，它的治疗管理已被提出维持DW的系统稳态平衡。结论HBD-2可能是一种重要的调节因子，通过促进细胞增殖和血管生成来控制慢性炎症和大小，为DW的治疗开辟了新的选择。

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引用次数: 1

Effects of PechaKucha presentation about prevention of pressure injury on knowledge of elderly care department students: a randomized controlled study. 一项随机对照研究:PechaKucha关于预防压伤的演讲对老年护理系学生知识的影响。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-05-01

Hale T Damar, Sueda Gür

Background: PechaKucha (PK) is a presentation technique that uses visual and narrative presentations consisting of 20 slides, each shown for 20 seconds.

Purpose: The aim of this study was to evaluate the effects of the PK presentation on elderly care department students' knowledge about pressure injury prevention.

Methods: This study used a single-blinded randomized control trial. Elderly care department students were randomized to the PK presentation technique (intervention group) and traditional PowerPoint presentations only (control group). The sample of the study consisted of 54 (intervention group = 28, control group = 26) elderly care department students. Data was collected using the Sociodemographic Form and the Pressure Ulcer Prevention Knowledge Assessment Instrument (PUPKAI). PUPKAI was administered before the presentations (pre-test), after the presentations (post-test 1), and 4 weeks after the presentations (post-test 2).

Results: Following the presentations, the intervention group's PUPKAI mean score (47.23 ± 11.62) was significantly higher than the control group's mean score (36.64 ± 12.41) (P < .05). Four weeks after completing the education, the intervention group's mean PUPKAI score (43.11 ± 13.72) was significantly higher than the control group's mean score (36.46 ± 12.76) (P < .05).

Conclusion: The knowledge level of the elderly care department students was found to be below the satisfactory level. It was determined that the PK presentation increased the knowledge level of the students regarding pressure injury prevention.

背景:PK (PechaKucha)是一种使用视觉和叙事的演示技术，由20张幻灯片组成，每张幻灯片播放20秒。目的:本研究的目的是评估PK演示对老年护理系学生压力损伤预防知识的影响。方法:采用单盲随机对照试验。老年护理系学生随机分为PK演示技术组(干预组)和传统ppt演示组(对照组)。研究对象为54名老年护理系学生(干预组28名，对照组26名)。使用社会人口学表格和压疮预防知识评估工具(PUPKAI)收集数据。干预组分别于演讲前(前测)、演讲后(后测1)、演讲后4周(后测2)进行pupukai评分。结果:演讲后干预组的平均评分(47.23±11.62)显著高于对照组的平均评分(36.64±12.41)(P < 0.05)。教育结束4周后，干预组的平均pupukai评分(43.11±13.72)显著高于对照组的平均评分(36.46±12.76)(P < 0.05)。结论:老年护理系学生的知识水平低于满意水平。结果表明，PK演示提高了学生对压力损伤预防的知识水平。

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引用次数: 0

Lessons Learned: A Disruption in Care Leads to Increased Rates of Proximal Amputations. 经验教训:护理中断导致近端截肢率增加。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-03-01 DOI: 10.25270/wmp.2023.1.4957

Justin Yu, Jai Joshi, Carmen Wong, Nafis Ahmed, Amit Rao, Timmy Li, Ammar Al Rubaiay, G. Landis, Alisha R. Oropallo

BACKGROUNDIn March 2020, due to the COVID-19 pandemic, hospitalizations in New York state were restricted to emergency purposes. Non-COVID related cases involving lower extremity wounds were only admitted for acute infections and limb salvage. Patients with these conditions were placed at higher risk for eventual limb loss.PURPOSETo understand the impact of COVID-19 on amputation rates.METHODSA retrospective review of lower limb institution-wide amputations was conducted at Northwell Health from January 2020 to January 2021. The amputation rates during the COVID-19 shutdown period were compared to the pre-pandemic, post-shutdown, and reopening period.RESULTSThe pre-pandemic period had 179 amputations, of which 8.38 % were proximal. 86 amputations were performed during shutdown, with a greater proportion being proximal (25.58 %, p=0.0009). Following the shutdown period, amputations returned to baseline. The proportion of proximal amputations during post-shutdown was 18.5 % and during reopening was 12.06 %. Patients had 4.89 times higher odds of undergoing a proximal amputation during the shutdown period.CONCLUSIONSThe effect of COVID-19 on amputation rates demonstrates an increase in proximal amputation during the initial shutdown. This study suggests an indirect negative effect of COVID-19 hospital restrictions on surgeries during the initial shutdown period.

背景2020年3月，由于新冠肺炎大流行，纽约州的住院治疗仅限于紧急情况。涉及下肢伤口的非新冠肺炎相关病例仅因急性感染和肢体抢救入院。患有这些疾病的患者最终失去肢体的风险更高。目的了解新冠肺炎对截肢率的影响。方法自2020年1月至2021年1月，在Northwell Health对全机构范围内的下肢截肢进行了回顾性审查。新冠肺炎关闭期间的截肢率与大流行前、关闭后和重新开放期间进行了比较。结果疫情前有179例截肢，其中8.38%是近端截肢。在停堆期间进行了86次截肢手术，其中近端截肢的比例更大（25.58%，p=0.00009）。停堆期结束后，截肢手术恢复到基线。关闭后近端截肢的比例为18.5%，重新开放时为12.06%。患者在停摆期间接受近端截肢的几率高出4.89倍。结论新冠肺炎对截肢率的影响表明，在最初关闭期间，近端截肢率增加。这项研究表明，新冠肺炎医院在最初关闭期间限制手术会产生间接负面影响。

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引用次数: 0

Lessons Learned: A Disruption in Care Leads to Increased Rates of Proximal Amputations. 经验教训:护理中断导致近端截肢率增加。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-03-01

Justin Yu, Jai Joshi, Carmen Wong, Nafis Ahmed, Amit Rao, Timmy Li, Ammar Al Rubaiay, Gregg Landis, Alisha Oropallo

Background: In March 2020, due to the COVID-19 pandemic, hospitalizations in New York state were restricted to emergency purposes. Non-COVID related cases involving lower extremity wounds were only admitted for acute infections and limb salvage. Patients with these conditions were placed at higher risk for eventual limb loss.

Purpose: To understand the impact of COVID-19 on amputation rates.

Methods: A retrospective review of lower limb institution-wide amputations was conducted at Northwell Health from January 2020 to January 2021. The amputation rates during the COVID-19 shutdown period were compared to the pre-pandemic, post-shutdown, and reopening period.

Results: The pre-pandemic period had 179 amputations, of which 8.38 % were proximal. 86 amputations were performed during shutdown, with a greater proportion being proximal (25.58 %, p=0.0009). Following the shutdown period, amputations returned to baseline. The proportion of proximal amputations during post-shutdown was 18.5 % and during reopening was 12.06 %. Patients had 4.89 times higher odds of undergoing a proximal amputation during the shutdown period.

Conclusions: The effect of COVID-19 on amputation rates demonstrates an increase in proximal amputation during the initial shutdown. This study suggests an indirect negative effect of COVID-19 hospital restrictions on surgeries during the initial shutdown period.

背景:2020年3月，由于COVID-19大流行，纽约州的住院治疗仅限于紧急情况。涉及下肢伤口的非covid相关病例仅因急性感染和肢体保留而入院。患有这些疾病的患者最终失去肢体的风险更高。目的:了解新冠肺炎疫情对截肢率的影响。方法:对2020年1月至2021年1月在Northwell Health进行的全机构下肢截肢进行回顾性分析。将COVID-19关闭期间的截肢率与大流行前、关闭后和重新开放期间进行比较。结果:大流行前发生截肢179例，近端截肢占8.38%。在关闭期间进行了86例截肢，近端截肢比例较大(25.58%，p=0.0009)。关闭后，截肢量恢复到基线水平。关闭后近端截肢比例为18.5%，重新开放时为12.06%。患者在关闭期间进行近端截肢的几率高出4.89倍。结论:COVID-19对截肢率的影响表明，在初始关闭期间，近端截肢率增加。这项研究表明，COVID-19医院限制在最初关闭期间对手术产生了间接的负面影响。

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引用次数: 0

Comparison of Wound Debridement Pressures With Updated Tests. 伤口清创压力与最新测试的比较。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-03-01 DOI: 10.25270/wmp.2023.1.2631

S. Fisher

BACKGROUNDWound debridement is one of the key treatment methods for chronic and acute wounds. Various tools are used to perform debridement, but the force applied to the tissue by these different instruments has been poorly documented in a limited number of past research efforts.PURPOSEThe aim of this study was to provide insight into the actual amount of pressure exerted on wound tissue.METHODSWe used a digital force transducer to measure the pressure applied by multiple combinations of angiocatheter needles (catheters), syringes, and other common debridement tools. The data obtained were compared with the pressure measurements reported by previous studies. The common standard used in research is a 35-mL syringe with a 19-gauge catheter with a pressure of 7 to 8 pounds per square inch (psi), which is regarded as the most effective for wound care.RESULTSMany of the instruments measured in this experiment closely reflected the pressure measurements previously published in the research literature and are safe to use to properly irrigate wounds. However, some discrepancies were also found, ranging from a small psi variability to several psi. Further studies and testing may be beneficial to confirm the results of this experiment.CONCLUSIONCertain tools produced higher pressures that were not suitable for routine wound care. Findings from this study can also be used by clinicians to choose appropriate tools and to monitor pressure when they use various common irrigation tools.

背景伤口清创是治疗慢性和急性创伤的关键方法之一。各种各样的工具被用来进行清创，但是在过去有限的研究中，这些不同的工具对组织施加的力的记录很少。目的本研究的目的是深入了解施加在伤口组织上的实际压力。方法我们使用数字力传感器测量血管导管针、注射器和其他常用清创工具的多种组合施加的压力。所获得的数据与先前研究报告的压力测量结果进行了比较。研究中使用的常用标准是一个35毫升的注射器和一个19号的导管，压力为每平方英寸7到8磅(psi)，这被认为是最有效的伤口护理。结果本实验中测量的许多仪器与先前发表的研究文献中的压力测量结果非常接近，可以安全地用于正确的伤口冲洗。然而，也发现了一些差异，从很小的psi变化到几个psi。进一步的研究和测试可能有助于证实本实验的结果。结论:某些工具产生较高的压力，不适合常规伤口护理。这项研究的结果也可以用于临床医生选择适当的工具，并监测压力时，他们使用各种常见的冲洗工具。

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引用次数: 1

Early Skin Temperature Characteristics of the Kennedy Lesion (Kennedy Terminal Ulcer). 肯尼迪病变（肯尼迪末期溃疡）的早期皮肤温度特征。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-03-01 DOI: 10.25270/wmp.2023.1.1424

K. Kennedy-Evans, Deanna M. Vargo, L. Ritter, D. Adams, Suzanne Koerner, Ellen Duell

BACKGROUNDPressure injuries are associated with skin temperature changes, but little is known about skin temperature characteristics of the Kennedy Lesion (KL).PURPOSEThe purpose of this study was to describe early skin temperature changes in KLs using long-wave infrared thermography.METHODSKLs were identified from chart review in 10 ICU patients. Skin assessments were performed within 24 hours of new skin discoloration. Temperature measurements were performed using a long-wave infrared thermography imaging system. Relative Temperature Differential (RTD) between the discolored area and a selected control point was calculated. RTDs of > +1.2 degrees C and < -1.2 degrees C were considered abnormal. Demographic data and observable characteristics of the KL were collected when available. Descriptive statistics (Mean plus/minus SD; % ) were used.RESULTSThe major finding of this study was that there were no early skin temperature differences between the KLs and surrounding skin.CONCLUSIONThe early stage of the KL may be limited to microvascular injury which results in a normal skin temperature. More studies are needed to verify this finding and to ascertain whether KL skin temperature changes over time. The study also supports the bedside use of thermography in skin temperature assessment.

背景压力损伤与皮肤温度变化有关，但对肯尼迪损伤（KL）的皮肤温度特征知之甚少。本研究的目的是使用长波红外热像图描述KL早期的皮肤温度变化。方法通过对10名ICU患者的图表回顾，确定了ODSKL。在新的皮肤变色后24小时内进行皮肤评估。使用长波红外热成像系统进行温度测量。计算变色区域和选定控制点之间的相对温差（RTD）。大于+1.2摄氏度和小于-1.2摄氏度的RTD被认为是异常的。人口统计学数据和KL的可观察特征在可用时收集。使用描述性统计（平均值加/减SD；%）。结果本研究的主要发现是KLs和周围皮肤之间没有早期皮肤温度差异。结论KL的早期可能局限于微血管损伤，导致皮肤温度正常。需要更多的研究来验证这一发现，并确定KL皮肤温度是否随时间变化。该研究还支持在床边使用热成像技术评估皮肤温度。

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引用次数: 1

Pain Management With Topical Ibuprofen in Partial-Thickness Burn Wounds and Effects on Wound Healing: A Prospective Randomized Clinical Study. 局部使用布洛芬治疗部分厚度烧伤伤口的疼痛管理及其对伤口愈合的影响：一项前瞻性随机临床研究。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-03-01 DOI: 10.25270/wmp.2023.1.3248

A. Akgun, Merve Alkin

BACKGROUNDPain management is important for patient comfort in the treatment of partial-thickness burn wounds. The topical application of ibuprofen provides analgesic and anti-inflammatory effects.PURPOSETo evaluate the efficacy of ibuprofen-containing foam dressing in partial-thickness burns.METHODSThe study included 50 patients with superficial second-degree burn wounds. Ibuprofen-containing foam dressing was used in 25 patients and paraffin gauze dressing in 25 patients as controls. The visual analogue score (VAS) was evaluated 30 min after dressing. On the 90th day following wound healing, the Vancouver scar scale (VSS) was administered to the patients to evaluate healing and scar formation.RESULTSThe rate of wound healing significantly increased in the study (ibuprofen-containing foam dressing) group compared to control group (8.84±2.97 vs 11.32±4.39, P = 0.010), and the frequency of dressing change significantly decreased in the study group vs control group (1.36±0.49 vs 5.68±2.07, P = 0.000). The oral analgesic needs and VAS scores of the patients were also found to be statistically significantly lower in the study group (5.04 ± 2.44) than for the control group (8.64 ± 1.29, P = 0.000). In the evaluation of the VSS, the total score was lower in the study group, but no statistically significant difference was observed.CONCLUSIONThe use of ibuprofen-containing foam dressing in patients with superficial second-degree burns eligible for outpatient follow-up provides effective pain management and increases patient comfort. It does not have a negative effect on wound healing. We consider that ibuprofen-containing foam dressing can be safely used in partial-thickness burns.

背景在治疗部分厚度烧伤伤口时，疼痛管理对患者的舒适度很重要。布洛芬的局部应用提供了镇痛和抗炎作用。目的评价含布洛芬泡沫敷料治疗部分厚度烧伤的疗效。方法本研究包括50例浅表二度烧伤患者。25例患者使用含布洛芬泡沫敷料，25例患者采用石蜡纱布敷料作为对照。敷料后30分钟评估视觉模拟评分（VAS）。在伤口愈合后的第90天，对患者进行温哥华疤痕量表（VSS），以评估愈合和疤痕形成。结果研究组（含布洛芬泡沫敷料）的伤口愈合率显著高于对照组（8.84±2.97 vs 11.32±4.39，P=0.010），与对照组相比，研究组换药频率显著降低（1.36±0.49 vs 5.68±2.07，P=0.000）。研究组患者的口腔镇痛需求和VAS评分（5.04±2.44）也显著低于对照组（8.64±1.29，P=0.000，研究组的总分较低，但没有观察到统计学上的显著差异。结论在符合门诊随访条件的浅表二度烧伤患者中使用含布洛芬的泡沫敷料可以有效地控制疼痛，增加患者的舒适度。它对伤口愈合没有负面影响。我们认为含有布洛芬的泡沫敷料可以安全地用于部分厚度烧伤。

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引用次数: 1

Comparison of Wound Debridement Pressures With Updated Tests. 伤口清创压力与最新测试的比较。

IF 1.2 4区医学 Q4 DERMATOLOGY

Wound management & prevention

Pub Date : 2023-03-01

Stacy Fisher

Background: Wound debridement is one of the key treatment methods for chronic and acute wounds. Various tools are used to perform debridement, but the force applied to the tissue by these different instruments has been poorly documented in a limited number of past research efforts.

Purpose: The aim of this study was to provide insight into the actual amount of pressure exerted on wound tissue.

Methods: We used a digital force transducer to measure the pressure applied by multiple combinations of angiocatheter needles (catheters), syringes, and other common debridement tools. The data obtained were compared with the pressure measurements reported by previous studies. The common standard used in research is a 35-mL syringe with a 19-gauge catheter with a pressure of 7 to 8 pounds per square inch (psi), which is regarded as the most effective for wound care.

Results: Many of the instruments measured in this experiment closely reflected the pressure measurements previously published in the research literature and are safe to use to properly irrigate wounds. However, some discrepancies were also found, ranging from a small psi variability to several psi. Further studies and testing may be beneficial to confirm the results of this experiment.

Conclusion: Certain tools produced higher pressures that were not suitable for routine wound care. Findings from this study can also be used by clinicians to choose appropriate tools and to monitor pressure when they use various common irrigation tools.

背景:创面清创是治疗慢性和急性创面的关键方法之一。各种各样的工具被用来进行清创，但是在过去有限的研究中，这些不同的工具对组织施加的力的记录很少。目的:本研究的目的是深入了解施加在伤口组织上的实际压力。方法:我们使用数字力传感器测量血管导管针(导管)、注射器和其他常见清创工具的多种组合施加的压力。所获得的数据与先前研究报告的压力测量结果进行了比较。研究中使用的常用标准是一个35毫升的注射器和一个19号的导管，压力为每平方英寸7到8磅(psi)，这被认为是最有效的伤口护理。结果:本实验中测量的许多仪器与先前研究文献中发表的压力测量结果非常接近，可以安全地用于正确的伤口冲洗。然而，也发现了一些差异，从很小的psi变化到几个psi。进一步的研究和测试可能有助于证实本实验的结果。结论:某些工具产生较高的压力，不适合常规伤口护理。这项研究的结果也可以用于临床医生选择适当的工具，并监测压力时，他们使用各种常见的冲洗工具。

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