L. Labban, Maysoun Kudsi, Z. Malek, Nasser K. Thallaj
Objectives: To evaluate the efficacy and safety of the Echinacea and ginger species extracts supplementation among patients with knee osteoarthritis (OA). Methods: Three hundred female patients with knee OA participated in this randomized study. They had OA of the knee and moderate-to-severe pain and they were divided into two groups. Study group (n=150) and control group (n=150). The study which lasted for 6-week. The study group received Ginger and Echinacea extract supplementations twice daily, with/ without acetaminophen. The study examined the reduction in "knee pain on standing for the study group (Ginger and Echinacea group)" defined by a reduction in pain of > or = 15 mm on a visual analog scale. The study measured other biological values such as BP, ESR, Creatinine and liver enzymes. Results: The supplementation of ginger and Echinacea extracts resulted in improvements in many values. Systolic blood pressure dropped from 120.5 ± 10.4 to 119.7 ± 8.9 mmHg, pain intensity VAS decreased from 6.9 ± 2.1 to 6.6 ± 1.5, ESR17.3 ± 11.9 and 21.0 ± 9.8mm/h, creatinine 0.87 ± 0.19mg/dl and 0.85 ± 0.16 mg/ dl and liver enzymes 21.6 ± 8.5 IU/L and 20.9 ± 4.5 IU/L for ALT and 20.9 ± 4.5 IU/L and 20.3 ± 7.4 IU/L for AST. Conclusion: The use of ginger extract in knee osteoarthritis patients had a moderately statistically significant effect on reducing pain with safe profile and mild GI adverse events.
{"title":"Pain Relieving Properties of Ginger (Z. officinale) and Echinacea (E. angustifolia) Extracts Supplementation among Female Patients with Osteoarthritis. A Randomized Study","authors":"L. Labban, Maysoun Kudsi, Z. Malek, Nasser K. Thallaj","doi":"10.5530/amdhs.2020.3.11","DOIUrl":"https://doi.org/10.5530/amdhs.2020.3.11","url":null,"abstract":"Objectives: To evaluate the efficacy and safety of the Echinacea and ginger species extracts supplementation among patients with knee osteoarthritis (OA). Methods: Three hundred female patients with knee OA participated in this randomized study. They had OA of the knee and moderate-to-severe pain and they were divided into two groups. Study group (n=150) and control group (n=150). The study which lasted for 6-week. The study group received Ginger and Echinacea extract supplementations twice daily, with/ without acetaminophen. The study examined the reduction in \"knee pain on standing for the study group (Ginger and Echinacea group)\" defined by a reduction in pain of > or = 15 mm on a visual analog scale. The study measured other biological values such as BP, ESR, Creatinine and liver enzymes. Results: The supplementation of ginger and Echinacea extracts resulted in improvements in many values. Systolic blood pressure dropped from 120.5 ± 10.4 to 119.7 ± 8.9 mmHg, pain intensity VAS decreased from 6.9 ± 2.1 to 6.6 ± 1.5, ESR17.3 ± 11.9 and 21.0 ± 9.8mm/h, creatinine 0.87 ± 0.19mg/dl and 0.85 ± 0.16 mg/ dl and liver enzymes 21.6 ± 8.5 IU/L and 20.9 ± 4.5 IU/L for ALT and 20.9 ± 4.5 IU/L and 20.3 ± 7.4 IU/L for AST. Conclusion: The use of ginger extract in knee osteoarthritis patients had a moderately statistically significant effect on reducing pain with safe profile and mild GI adverse events.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127765051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kmd Hossain, S. Roy, Mohammad Mosayed Ullah, R. Kabir, S. Arafat
Bangladesh is expected to face a rapid upraise of SARS- CoV-2 outbreak and the nation is in a state of locked down. Evidences suggests a nation suffers a wide range of mental health issues related to anxiety, fear, isolation, depression, panic, emotional outburst and sleep disturbances during COVID 19 pandemic. The psychological impairments are significant to the diagnosed cases, suspected cases, quarantine cases, health workers and their families and relatives. But the health individual spending times with an experience of pandemic are also vulnerable for mental health crisis. There are structured approaches and strategies for the management of this crisis that needs to be taken into account for a comprehensive strategy to meet the spreading challenge in the next potential horizon of COVID 19.
{"title":"COVID-19 and Mental Health Challenges in Bangladesh","authors":"Kmd Hossain, S. Roy, Mohammad Mosayed Ullah, R. Kabir, S. Arafat","doi":"10.5530/amdhs.2020.2.8","DOIUrl":"https://doi.org/10.5530/amdhs.2020.2.8","url":null,"abstract":"Bangladesh is expected to face a rapid upraise of SARS- CoV-2 outbreak and the nation is in a state of locked down. Evidences suggests a nation suffers a wide range of mental health issues related to anxiety, fear, isolation, depression, panic, emotional outburst and sleep disturbances during COVID 19 pandemic. The psychological impairments are significant to the diagnosed cases, suspected cases, quarantine cases, health workers and their families and relatives. But the health individual spending times with an experience of pandemic are also vulnerable for mental health crisis. There are structured approaches and strategies for the management of this crisis that needs to be taken into account for a comprehensive strategy to meet the spreading challenge in the next potential horizon of COVID 19.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123990477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This is a case of breakthrough seizure and use of valproic acid (VPA) in management. Objective is to discuss the systematic approach in pharmacological treatment of epilepsy. Day one, patient was initiated with intravenous infusion of phenytoin 800mg, tablet phenytoin 300mg OD and tablet VPA 400mg TDS. Tablet VPA doses were withheld at Day 2 after Therapeutic Drug Monitoring (TDM) toxic levels. Patient was discharged with tablet VPA 400mg BD and tablet levetiracetam 500mg BD. In the beginning of therapy, a single pharmacotherapeutic agent is introduced cautiously to reduce any unwanted incidences of idiosyncratic and dose related toxicity. The pharmaco therapeutic agent dose must then be increased gradually to a maximum tolerated drug-dose therapeutic response. If this agent is not tolerated, it can be substituted with another agent for efficacious mono therapy. If seizures prevail, despite adequate trials of two appropriate agents, then poly therapy should be initiated. Patients need to be informed about the objectives of therapy and
{"title":"Systematic Approach in Long Term Pharmacological Treatment of Epilepsy: A Case Report on the Use of Valproic Acid","authors":"Captain Manvikram Singh Gill","doi":"10.5530/amdhs.2020.2.7","DOIUrl":"https://doi.org/10.5530/amdhs.2020.2.7","url":null,"abstract":"This is a case of breakthrough seizure and use of valproic acid (VPA) in management. Objective is to discuss the systematic approach in pharmacological treatment of epilepsy. Day one, patient was initiated with intravenous infusion of phenytoin 800mg, tablet phenytoin 300mg OD and tablet VPA 400mg TDS. Tablet VPA doses were withheld at Day 2 after Therapeutic Drug Monitoring (TDM) toxic levels. Patient was discharged with tablet VPA 400mg BD and tablet levetiracetam 500mg BD. In the beginning of therapy, a single pharmacotherapeutic agent is introduced cautiously to reduce any unwanted incidences of idiosyncratic and dose related toxicity. The pharmaco therapeutic agent dose must then be increased gradually to a maximum tolerated drug-dose therapeutic response. If this agent is not tolerated, it can be substituted with another agent for efficacious mono therapy. If seizures prevail, despite adequate trials of two appropriate agents, then poly therapy should be initiated. Patients need to be informed about the objectives of therapy and","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114564709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olanrewaju Olanrewaju O, Omoniyi Isaac, Oladapo Oladapo O, A. Adesola, D. Bukola, Odunuga Odunuga O, Basirat Adebowale
Background: Excessive weight gain, obesity and poor lifestyles are some of the predisposing factors to the burden of non-communicable diseases (NCDs) especially among in Africa continent and other region of the world. Objectives: This study assessed the lifestyles patterns and Anthropometric indices of staff in Jos University Teaching Hospital, Jos, Nigeria. Methods: It was descriptive cross-sectional study which involved 283 staffs who were randomly selected from all the department in the hospital Information were sourced from participants on medical history, dietary habits and lifestyles patterns using a structured, self-administered questionnaire and anthropometric indices. Data were analyzed using descriptive statistics and chi-square. In all cases, a probability of (<0.05) were taken to indicates level of significance. Results: More than half (64.3%) of the respondents were within the age of 30-49 years. More (68%) female health workers participated in the study than male workers (32%). More half of the respondents (56.2%) had parents that were suffering chronic diseases. Only (21.6%) of the respondents drink alcohol, 2.5% smoke cigarette, 65% did not engage in physical exercise. Large number (86.2%) of the respondents always adds vegetables to their diet and 39.1% took fruit regularly while about 56.2% of the respondent’s parents had chronic diseases. Prevalence of Overweight/Obesity as determined by abnormal values for BMI, WC, WHR and BIA were 48.9%, 31.1%, 43.1% and 65% respectively. Conclusion: This study observed a high level of abnormal body weight status and low consumption of fruits among the hospital staff.
{"title":"Lifestyles patterns and Anthropometric Indices of Healthcare Staff in Jos University Teaching Hospital, Jos, Nigeria","authors":"Olanrewaju Olanrewaju O, Omoniyi Isaac, Oladapo Oladapo O, A. Adesola, D. Bukola, Odunuga Odunuga O, Basirat Adebowale","doi":"10.5530/amdhs.2020.2.5","DOIUrl":"https://doi.org/10.5530/amdhs.2020.2.5","url":null,"abstract":"Background: Excessive weight gain, obesity and poor lifestyles are some of the predisposing factors to the burden of non-communicable diseases (NCDs) especially among in Africa continent and other region of the world. Objectives: This study assessed the lifestyles patterns and Anthropometric indices of staff in Jos University Teaching Hospital, Jos, Nigeria. Methods: It was descriptive cross-sectional study which involved 283 staffs who were randomly selected from all the department in the hospital Information were sourced from participants on medical history, dietary habits and lifestyles patterns using a structured, self-administered questionnaire and anthropometric indices. Data were analyzed using descriptive statistics and chi-square. In all cases, a probability of (<0.05) were taken to indicates level of significance. Results: More than half (64.3%) of the respondents were within the age of 30-49 years. More (68%) female health workers participated in the study than male workers (32%). More half of the respondents (56.2%) had parents that were suffering chronic diseases. Only (21.6%) of the respondents drink alcohol, 2.5% smoke cigarette, 65% did not engage in physical exercise. Large number (86.2%) of the respondents always adds vegetables to their diet and 39.1% took fruit regularly while about 56.2% of the respondent’s parents had chronic diseases. Prevalence of Overweight/Obesity as determined by abnormal values for BMI, WC, WHR and BIA were 48.9%, 31.1%, 43.1% and 65% respectively. Conclusion: This study observed a high level of abnormal body weight status and low consumption of fruits among the hospital staff.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123728336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The evolution in the field of medicine is to develop new drugs to treat an ailment. So, it is never that the finding a better drug for treatment can stop. But the debate on picking a natural or synthetic system of medicine with the better ability to treat will be eternal. This creates dilemma in the treatment of different diseases and disorder and so in the nephrotoxicity. As we go through the literatures, we find different ways and drugs for the treatment of nephrotoxicity. Every system has advantages and corresponding disadvantages within itself corresponding to that of drugs. This article is all about the different nephroprotective drug used or present in literature, there advantages (nephroprotection ability) and disadvantages (side effects and less efficacy).
{"title":"Drug Induced Nephrotoxicity Treatment: Synthetic and Herbal Drugs","authors":"Sabreena Naz, Kislaya Mishra, A. Rizvi","doi":"10.5530/amdhs.2020.2.6","DOIUrl":"https://doi.org/10.5530/amdhs.2020.2.6","url":null,"abstract":"The evolution in the field of medicine is to develop new drugs to treat an ailment. So, it is never that the finding a better drug for treatment can stop. But the debate on picking a natural or synthetic system of medicine with the better ability to treat will be eternal. This creates dilemma in the treatment of different diseases and disorder and so in the nephrotoxicity. As we go through the literatures, we find different ways and drugs for the treatment of nephrotoxicity. Every system has advantages and corresponding disadvantages within itself corresponding to that of drugs. This article is all about the different nephroprotective drug used or present in literature, there advantages (nephroprotection ability) and disadvantages (side effects and less efficacy).","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122763120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Habibullah Habibullah H, Faria Khurshid, M. Younus, N. ul Haq, Y. Sadiq, M. Zahir, A. Naseem
Background: Appendicitis is condition which describes and explain inflammation of appendix. Signs and symptoms of appendicitis are generally severe discomfort in lower right part of abdominal cavity, vomiting, nausea and loss of appetite while around 40% of people do not show these distinctive characteristics of appendicitis. For management of acute appendicitis appendectomy is required on urgent basis. The incidence of surgical wound infections or surgical sites infections are greatly reduced by administration of antibiotics prophylactically. Methodology: This cross sectional study was conducted for minor and major surgery patients of appendicitis at Sandman Provincial Hospital Quetta and Bolan Medical Complex Hospital Quetta. The study was carried out over period of 4 months between May 2018 and September 2018. Convenient sampling method was adopted for enrolling study patients A standardized data collection form was developed based on recommendations of Center for Disease Control (CDC) guiding principle for inhibition of SSI was used. Ethical approval was obtained from Ethical Committee of Faculty of Pharmacy and Health Sciences, University of Balochistan Quetta. Results: Results showed that majority of patients of appendicitis 133 (68.2%) were from age group 1 to 20 years. Majority of participants that had undergone surgery for appendicitis were male 114 (58.5%). Majority of respondents belonged to the urban area i.e 123. Outcomes on follow up showed majority of the patients had healed their wound which were using prescribed antibiotics for post-operative care. Only one patient reported the sepsis. Metronidazole was prescribed to most of the patient’s i.e 183, Ceftriaxone to 162, Gentamicin to 155, Moxifloxacin to 19 among other antibiotics. Conclusion: The current study demonstrated that antibiotics are rationally prescribed in tertiary care hospitals of Quetta, also prophylactic and post-operative prescribing of antibiotics yield the desired outcomes.
{"title":"Evaluation of Antibiotics used and Treatment Outcomes in Postoperative Appendectomy Patients","authors":"Habibullah Habibullah H, Faria Khurshid, M. Younus, N. ul Haq, Y. Sadiq, M. Zahir, A. Naseem","doi":"10.5530/amdhs.2019.4.14","DOIUrl":"https://doi.org/10.5530/amdhs.2019.4.14","url":null,"abstract":"Background: Appendicitis is condition which describes and explain inflammation of appendix. Signs and symptoms of appendicitis are generally severe discomfort in lower right part of abdominal cavity, vomiting, nausea and loss of appetite while around 40% of people do not show these distinctive characteristics of appendicitis. For management of acute appendicitis appendectomy is required on urgent basis. The incidence of surgical wound infections or surgical sites infections are greatly reduced by administration of antibiotics prophylactically. Methodology: This cross sectional study was conducted for minor and major surgery patients of appendicitis at Sandman Provincial Hospital Quetta and Bolan Medical Complex Hospital Quetta. The study was carried out over period of 4 months between May 2018 and September 2018. Convenient sampling method was adopted for enrolling study patients A standardized data collection form was developed based on recommendations of Center for Disease Control (CDC) guiding principle for inhibition of SSI was used. Ethical approval was obtained from Ethical Committee of Faculty of Pharmacy and Health Sciences, University of Balochistan Quetta. Results: Results showed that majority of patients of appendicitis 133 (68.2%) were from age group 1 to 20 years. Majority of participants that had undergone surgery for appendicitis were male 114 (58.5%). Majority of respondents belonged to the urban area i.e 123. Outcomes on follow up showed majority of the patients had healed their wound which were using prescribed antibiotics for post-operative care. Only one patient reported the sepsis. Metronidazole was prescribed to most of the patient’s i.e 183, Ceftriaxone to 162, Gentamicin to 155, Moxifloxacin to 19 among other antibiotics. Conclusion: The current study demonstrated that antibiotics are rationally prescribed in tertiary care hospitals of Quetta, also prophylactic and post-operative prescribing of antibiotics yield the desired outcomes.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132806210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Deo, S. Rijal, S. Kunwar, S. Yadav, Sujaya Gupta
Introduction: In developing countries drug monitoring system is not efficient and patients can easily buy drugs without any prescription. The users believe those drugs to be all safe. There is more awareness regarding over-the-counter drugs in urban population. Objectives: To assess the awareness and practice of over-the-counter (OTC) drugs among young and adults in a selected Nepalese community. Materials and Methods: A descriptive cross-sectional study was carried out among people of Basundhara, Kathmandu of age group 20-40 years. Non-probability convenience sampling was done to select 384 respondents. Structured questionnaire was used for data collection. The data was analysed in SPSS version 16.0 program. Results: The majority of the participants were in the age range of 31-40 years with the mean age of 30.16±5.28. Findings regarding the awareness revealed that 60.7% and 88.1% participants knew the correct meaning and precaution of over-the-counter drugs respectively, 32.8% obtained the information through friends, 55.2% told that easy accessibility was the reason for taking OTC drugs. Drugs using without prescription were 92.4%, 80.2% reuse the previous prescription when the illness was similar, 75.3% suggested others to take over the counter drugs and 46.1% used the medicine even if its color and odor was unusual. Conclusion: In conclusion, people are aware about over-the-counter drugs. However, they are taking it rampantly and seem uncontrollable too. Thus, it is important to organise the continuing education for pharmacists and awareness program by policy makers to the community people about appropriate use of OTC medications to prevent the chances of drug misuse.
{"title":"Awareness and Practice of Over-the-Counter Drugs in a Selected Community of Nepal","authors":"S. Deo, S. Rijal, S. Kunwar, S. Yadav, Sujaya Gupta","doi":"10.5530/amdhs.2019.4.13","DOIUrl":"https://doi.org/10.5530/amdhs.2019.4.13","url":null,"abstract":"Introduction: In developing countries drug monitoring system is not efficient and patients can easily buy drugs without any prescription. The users believe those drugs to be all safe. There is more awareness regarding over-the-counter drugs in urban population. Objectives: To assess the awareness and practice of over-the-counter (OTC) drugs among young and adults in a selected Nepalese community. Materials and Methods: A descriptive cross-sectional study was carried out among people of Basundhara, Kathmandu of age group 20-40 years. Non-probability convenience sampling was done to select 384 respondents. Structured questionnaire was used for data collection. The data was analysed in SPSS version 16.0 program. Results: The majority of the participants were in the age range of 31-40 years with the mean age of 30.16±5.28. Findings regarding the awareness revealed that 60.7% and 88.1% participants knew the correct meaning and precaution of over-the-counter drugs respectively, 32.8% obtained the information through friends, 55.2% told that easy accessibility was the reason for taking OTC drugs. Drugs using without prescription were 92.4%, 80.2% reuse the previous prescription when the illness was similar, 75.3% suggested others to take over the counter drugs and 46.1% used the medicine even if its color and odor was unusual. Conclusion: In conclusion, people are aware about over-the-counter drugs. However, they are taking it rampantly and seem uncontrollable too. Thus, it is important to organise the continuing education for pharmacists and awareness program by policy makers to the community people about appropriate use of OTC medications to prevent the chances of drug misuse.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116567563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aadil Ali, N. Haq, Kainat Chang, S. Naqi, Muhammad Rafique, Muhammad Ismail, Rabbia Naseer, A. Nasim, Muhammad Kumail
Many frail older adults are slim, weak and under nourished; this part of frailty remains a critical concern in the old age. However, there is also strong conformation that excessive obesity contributes to frailty, therefore, present study was conducted to assess the Relationship between Obesity and Frailty in Older Population of Karachi, Pakistan. A cross sectional survey was conducted in different hospitals of Karachi, Pakistan from January to March 2018. BMI was measured by standard procedure in already diagnosed 377 patients of Fraility (mild and sever) and SPSS version 23 was used to analyze the data. The majority were ( n =215, 57%) male and having age between 61 to 63 years ( n =75, 19.9%), overweight ( n =151, 40%) and Obese were ( n =37, 9.8%) no significant correlation was found between obesity and frailty. This Study concluded that there is no significance of obesity on Fraility, because mostly the government facilities are being attended by the poor patients and the rich patients who may have the obesity along with Fraility may go to the private institutes.
{"title":"Impact of Obesity on Frailty in Older Population of Karachi, Pakistan","authors":"Aadil Ali, N. Haq, Kainat Chang, S. Naqi, Muhammad Rafique, Muhammad Ismail, Rabbia Naseer, A. Nasim, Muhammad Kumail","doi":"10.5530/amdhs.2019.4.15","DOIUrl":"https://doi.org/10.5530/amdhs.2019.4.15","url":null,"abstract":"Many frail older adults are slim, weak and under nourished; this part of frailty remains a critical concern in the old age. However, there is also strong conformation that excessive obesity contributes to frailty, therefore, present study was conducted to assess the Relationship between Obesity and Frailty in Older Population of Karachi, Pakistan. A cross sectional survey was conducted in different hospitals of Karachi, Pakistan from January to March 2018. BMI was measured by standard procedure in already diagnosed 377 patients of Fraility (mild and sever) and SPSS version 23 was used to analyze the data. The majority were ( n =215, 57%) male and having age between 61 to 63 years ( n =75, 19.9%), overweight ( n =151, 40%) and Obese were ( n =37, 9.8%) no significant correlation was found between obesity and frailty. This Study concluded that there is no significance of obesity on Fraility, because mostly the government facilities are being attended by the poor patients and the rich patients who may have the obesity along with Fraility may go to the private institutes.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130491882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nuchal cords have been invariably seen in pregnancies, sometimes discovered antenatally while more often as an incidental finding during birth. It sometimes can present as a complication to active labour, leading to unpredictable maternal and peri-natal morbidity and mortality. However, as often as nuchal cords are witnessed in clinical scenarios, only little is known in peer reviewed literature about their significance. There is an existing practical deficiency of guidelines and algorithmic measures to ensure maternal and neonatal wellbeing in a case of cord around neck. Diagnosis of nuchal cord is still a challenge during antenatal evaluation and not often taken in concern by obstetricians. In our study we study the incidence of nuchal cords with its overall aftermath with respect to maternal and neonatal parameters and attempt to probe the likely importance for its screening and developing guidelines.
{"title":"To Evaluate the Association of Cord around Neck at the Time of Delivery with Maternal and Peri-natal Outcomes","authors":"Rahul Kumar, S. Jamal, A. Verma","doi":"10.5530/amdhs.2019.3.11","DOIUrl":"https://doi.org/10.5530/amdhs.2019.3.11","url":null,"abstract":"Nuchal cords have been invariably seen in pregnancies, sometimes discovered antenatally while more often as an incidental finding during birth. It sometimes can present as a complication to active labour, leading to unpredictable maternal and peri-natal morbidity and mortality. However, as often as nuchal cords are witnessed in clinical scenarios, only little is known in peer reviewed literature about their significance. There is an existing practical deficiency of guidelines and algorithmic measures to ensure maternal and neonatal wellbeing in a case of cord around neck. Diagnosis of nuchal cord is still a challenge during antenatal evaluation and not often taken in concern by obstetricians. In our study we study the incidence of nuchal cords with its overall aftermath with respect to maternal and neonatal parameters and attempt to probe the likely importance for its screening and developing guidelines.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132009262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anchusa azurea (Syn. Anchusa italica) belong to the Boraginaceae family and were distributed in the temperate, especially in Mediterranean regions. Chemical studies showed that A. azurea contains mainly triterpenes and polyphenols. A. azurea possessed many pharmacological effects; these included anticancer, antioxidant and antiviral effects etc. The aim of this review article is to gather information about A. azurea which is currently scattered in form of various publications PubMed, Science Direct and Elsevier etc. Through this review article we tried to attract the attention of people for therapeutic potential of A. azurea. The present review comprises upto date information of traditional uses, phytochemistry and pharmacology of A. azurea. Some progress has been made, but still consistent efforts are required to explore the individual compounds isolated A. azurea to validate and understand its traditional uses and clinical practices. This review article provides preliminary information and gives a direction for the basic and clinical research on A. azurea.
{"title":"A Comprehensive Review on Pharmacognostical and Pharmacological Characters of Anchusa azurea","authors":"F. Hussain, J. Ahamad, Peshawa Osw","doi":"10.5530/amdhs.2019.3.10","DOIUrl":"https://doi.org/10.5530/amdhs.2019.3.10","url":null,"abstract":"Anchusa azurea (Syn. Anchusa italica) belong to the Boraginaceae family and were distributed in the temperate, especially in Mediterranean regions. Chemical studies showed that A. azurea contains mainly triterpenes and polyphenols. A. azurea possessed many pharmacological effects; these included anticancer, antioxidant and antiviral effects etc. The aim of this review article is to gather information about A. azurea which is currently scattered in form of various publications PubMed, Science Direct and Elsevier etc. Through this review article we tried to attract the attention of people for therapeutic potential of A. azurea. The present review comprises upto date information of traditional uses, phytochemistry and pharmacology of A. azurea. Some progress has been made, but still consistent efforts are required to explore the individual compounds isolated A. azurea to validate and understand its traditional uses and clinical practices. This review article provides preliminary information and gives a direction for the basic and clinical research on A. azurea.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120922916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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