J. Ahamad, M. Ameen, E. T. Anwer, Subasini Uthirapathy, O. Porwal
Background: Andrographis paniculata Wall. commonly known as Kalmegh and widely used for the treatment of the liver complications in Indian sub-continent. It is important ingredient of several traditional herbal formulations. Materials and Methods: Hence we planned to developed quick qualitative and quantitative standardization method for its quality control by using TLC and UV-visible spectroscopic methods for its better therapeutic efficacy. Results: TLC and UV-visible spectroscopic method has been developed for identification and quantification of andrographolide in A. paniculata herb samples. The developed TLC resulted in well resolved spots of different constituents of herb along with andrographolide standard. The developed UV-visible spectroscopic method was used for the estimation of andrographolide in A. paniculata herb samples. Conclusions: These quick standardization methods are used as analytical tool for the routine analysis of A. paniculata herb samples for achieving better therapeutic effects.
{"title":"Qualitative and Quantitative Standardization of Andrographis paniculata by TLC Technique and UV Method","authors":"J. Ahamad, M. Ameen, E. T. Anwer, Subasini Uthirapathy, O. Porwal","doi":"10.5530/amdhs.2019.3.9","DOIUrl":"https://doi.org/10.5530/amdhs.2019.3.9","url":null,"abstract":"Background: Andrographis paniculata Wall. commonly known as Kalmegh and widely used for the treatment of the liver complications in Indian sub-continent. It is important ingredient of several traditional herbal formulations. Materials and Methods: Hence we planned to developed quick qualitative and quantitative standardization method for its quality control by using TLC and UV-visible spectroscopic methods for its better therapeutic efficacy. Results: TLC and UV-visible spectroscopic method has been developed for identification and quantification of andrographolide in A. paniculata herb samples. The developed TLC resulted in well resolved spots of different constituents of herb along with andrographolide standard. The developed UV-visible spectroscopic method was used for the estimation of andrographolide in A. paniculata herb samples. Conclusions: These quick standardization methods are used as analytical tool for the routine analysis of A. paniculata herb samples for achieving better therapeutic effects.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128826853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ushasree Adepu, Harinandani Appam, Brahmani Bachu, Avinassh Tippani, S. Anchuri
{"title":"Analysis of Fine Needle Aspiration Cytology in Diagnosing the Patients with Breast Lump: A Prospective Study","authors":"Ushasree Adepu, Harinandani Appam, Brahmani Bachu, Avinassh Tippani, S. Anchuri","doi":"10.5530/AMDHS.2019.2.7","DOIUrl":"https://doi.org/10.5530/AMDHS.2019.2.7","url":null,"abstract":"","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115268847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nitish Bhat, K. Thakur, Nandini Bharadwaj, Ramandeep Singh
Decalcification of hard tissues has remained an important part in visualizing the histology of the section. For the process of decalcification various decalcifying agents have been used in the past but very limited studies can be found in the literature about the comparison of various decalcifying agents. Aim: Here we present a study comparing three different decalcifying agents (10% Nitric acid, EDTA, 10 % Formic acid). Methodology: 30 freshly extracted premolars were decalcified using three different decalcifying agents. The end point of decalcification was tested by chemical methods. The decalcified sections were routinely processed and staining was done using Hematoxylin and Eosin. Result: Sections decalcified with EDTA gave better results as compared to the other two groups. Conclusion: EDTA is a better option for decalcification of tooth but it has a slow rate of action. So, for the cases requiring urgent results nitric acid can be used.
{"title":"Comparision of 10% Nitric Acid, Edta and 10% Formic Acid for Tooth Decalcification","authors":"Nitish Bhat, K. Thakur, Nandini Bharadwaj, Ramandeep Singh","doi":"10.5530/AMDHS.2019.2.8","DOIUrl":"https://doi.org/10.5530/AMDHS.2019.2.8","url":null,"abstract":"Decalcification of hard tissues has remained an important part in visualizing the histology of the section. For the process of decalcification various decalcifying agents have been used in the past but very limited studies can be found in the literature about the comparison of various decalcifying agents. Aim: Here we present a study comparing three different decalcifying agents (10% Nitric acid, EDTA, 10 % Formic acid). Methodology: 30 freshly extracted premolars were decalcified using three different decalcifying agents. The end point of decalcification was tested by chemical methods. The decalcified sections were routinely processed and staining was done using Hematoxylin and Eosin. Result: Sections decalcified with EDTA gave better results as compared to the other two groups. Conclusion: EDTA is a better option for decalcification of tooth but it has a slow rate of action. So, for the cases requiring urgent results nitric acid can be used.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120979406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Malaria Elimination Research Alliance (MERA) - The Launch of a Milestone","authors":"S. Hossain","doi":"10.5530/AMDHS.2019.2.5","DOIUrl":"https://doi.org/10.5530/AMDHS.2019.2.5","url":null,"abstract":"","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128238393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comprehensive Review on Selected Traditional Herbs in the Treatment of Metabolic Syndrome","authors":"J. Ahamad","doi":"10.5530/AMDHS.2019.2.6","DOIUrl":"https://doi.org/10.5530/AMDHS.2019.2.6","url":null,"abstract":"","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114519556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fazal ur Rehman Khilji, Q. Iqbal, S. Haider, Muhammad Anwar, A. Khalid, Fazal Muhammad, A. Zarkoon, F. Saleem
Introduction: Congestive Heart Failure (CHF) in patients with dialysis is a concern increasing morbidity and mortality. Research was conducted to evaluate CHF in dialysis patients; it`s frequency and prognosis among patients attending public healthcare institutions in Pakistan. Methods: This was a multicenter cohort study whereby data of 117 patients for one year was evaluated retrospectively. Results: All patients had End-Stage Renal Disease (ESRD) and were on regular maintenance hemodialysis therapy. 7.7 % patients had Non-Insulin Dependent Diabetes Mellitus, 4.3% had Ischemic Heart Disease, 78.6% had Left Ventricular Hypertrophy and 80.34% had Cardiomyopathy. 38.5% were confirmed with CHF. 31.6% had systolic dysfunction, 6.8% had diastolic dysfunction and 3.4% had both systolic and diastolic dysfunction. Among patients with systolic dysfunction, 2.6% measured Left Ejection Ventricle Fraction (LEVF) of ≤ 20%, 13.7% measured 21-30% and 15.4% measured 3-40%. Additionally, 28.9% developed de novo CHF. Recurrence of CHF was observed in 57.7% and mortality rate was 24% in CHF group. Conclusion: Incidence of CHF was relatively high in these patients. Frequent recurrence of the disease, re-hospitalization and enhanced mortality is evident of adverse prognosis of CHF in ESRD patients. CVD must not be considered separately in ESRD patients. Appropriate management and correction of risk factors of co-morbid conditions can be helpful in improving the disease condition..
{"title":"Frequency, Prognosis and Risk Factors of Congestive Heart Failure in Dialysis Patients Attending Public Hospitals in Pakistan","authors":"Fazal ur Rehman Khilji, Q. Iqbal, S. Haider, Muhammad Anwar, A. Khalid, Fazal Muhammad, A. Zarkoon, F. Saleem","doi":"10.5530/AMDHS.2019.1.4","DOIUrl":"https://doi.org/10.5530/AMDHS.2019.1.4","url":null,"abstract":"Introduction: Congestive Heart Failure (CHF) in patients with dialysis is a concern increasing morbidity and mortality. Research was conducted to evaluate CHF in dialysis patients; it`s frequency and prognosis among patients attending public healthcare institutions in Pakistan. Methods: This was a multicenter cohort study whereby data of 117 patients for one year was evaluated retrospectively. Results: All patients had End-Stage Renal Disease (ESRD) and were on regular maintenance hemodialysis therapy. 7.7 % patients had Non-Insulin Dependent Diabetes Mellitus, 4.3% had Ischemic Heart Disease, 78.6% had Left Ventricular Hypertrophy and 80.34% had Cardiomyopathy. 38.5% were confirmed with CHF. 31.6% had systolic dysfunction, 6.8% had diastolic dysfunction and 3.4% had both systolic and diastolic dysfunction. Among patients with systolic dysfunction, 2.6% measured Left Ejection Ventricle Fraction (LEVF) of ≤ 20%, 13.7% measured 21-30% and 15.4% measured 3-40%. Additionally, 28.9% developed de novo CHF. Recurrence of CHF was observed in 57.7% and mortality rate was 24% in CHF group. Conclusion: Incidence of CHF was relatively high in these patients. Frequent recurrence of the disease, re-hospitalization and enhanced mortality is evident of adverse prognosis of CHF in ESRD patients. CVD must not be considered separately in ESRD patients. Appropriate management and correction of risk factors of co-morbid conditions can be helpful in improving the disease condition..","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126784359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saurabh Nimesh, R. Tomar, Manoj Kumar, Nitish Tyagi, P. Shukla
Erectile dysfunction or Sexual dysfunction or male impotence is defined as the inability of a man to achieve and maintain an erection sufficient for mutually satisfactory intercourse with his partner. Sexual health and function are important determinants of quality of life. ED is a significant and common medical problem. An estimated 150 million men worldwide have some degree of ED, and more than twice that many are expected to be affected by 2025. Several orally active drugs Apomorphine sublingual, Sildenafil, Vardenafil, Tadalafil and Avanafil are currently prescribed for the treatment of ED to improve the arterial blood flow to the penile tissue. Herbal medicinal plants and their extracts have been used in traditional medicine in treatment of ED. These herbal medicinal drugs are including Ginseng, Ashwagandha, Yohimbine, Safed musli, Shilajit, Ginkgo. The present review provides an overview of the knowledge of ED or sexual dysfunction at the time.
{"title":"Erectile Dysfunction: An Update","authors":"Saurabh Nimesh, R. Tomar, Manoj Kumar, Nitish Tyagi, P. Shukla","doi":"10.5530/AMDHS.2019.1.3","DOIUrl":"https://doi.org/10.5530/AMDHS.2019.1.3","url":null,"abstract":"Erectile dysfunction or Sexual dysfunction or male impotence is defined as the inability of a man to achieve and maintain an erection sufficient for mutually satisfactory intercourse with his partner. Sexual health and function are important determinants of quality of life. ED is a significant and common medical problem. An estimated 150 million men worldwide have some degree of ED, and more than twice that many are expected to be affected by 2025. Several orally active drugs Apomorphine sublingual, Sildenafil, Vardenafil, Tadalafil and Avanafil are currently prescribed for the treatment of ED to improve the arterial blood flow to the penile tissue. Herbal medicinal plants and their extracts have been used in traditional medicine in treatment of ED. These herbal medicinal drugs are including Ginseng, Ashwagandha, Yohimbine, Safed musli, Shilajit, Ginkgo. The present review provides an overview of the knowledge of ED or sexual dysfunction at the time.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126271686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer- I am and I will","authors":"S. Hossain","doi":"10.5530/AMDHS.2019.1.2","DOIUrl":"https://doi.org/10.5530/AMDHS.2019.1.2","url":null,"abstract":"","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"108 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114090421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacy Informatics: An Emerging Field","authors":"S. Atique, Chien-Yeh Hsu","doi":"10.5530/AMDHS.2019.1.1","DOIUrl":"https://doi.org/10.5530/AMDHS.2019.1.1","url":null,"abstract":"","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124491206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To explore the National Survey of Drug Information Centers practice in Saudi Arabia: Research and Publications at MOH hospitals. Methods: It is a cross-sectional four months national survey of Drug Information Services at MOH. It contained ten domains with 181 questions designed by the authors. It was derived from Internal Pharmaceutical Federation, American Society of Health-System Pharmacists best practice guidelines. This survey was distributed to forty hospital pharmacies that run drug information services. In this study, the domain Research and Publications System was explored and analyzed. It consisted of eight questions about the written policy and procedure and application methods for Research and Publications at MOH system in the drug information centers. All analysis was done through survey monkey system. Results: The survey was distributed to 45 of hospitals, the response rate, was 40 (88.88%) hospitals. The highest score of investigational drug services was a written policy and procedure for IDS did not exist in 23 (57.5%) hospitals while only 6 (15%) of hospitals 100% applied the elements. The highest score of Pharmacy Professional Publications Services was the written policy and procedure for Professional Publications Services did not exist in 24 (60%) hospitals while only 6 (15%) of hospitals 100% applied the elements. The highest scores of Pharmacy Ethical and Legal Issues was a Written policy and procedure for Pharmacy Ethical and Legal did not exist in 20 (50%) hospitals while only 7 (17.5%) of hospitals 100% applied the elements. Conclusion: There was a weak implementation of Research and Publications system in drug information centers practice. An educating and training of drug information pharmacist on the Research and Publications system is required.in addition to setup up policy and procedures during the implementation of the services.
{"title":"National Survey of Drug Information Centers Practice: Research and Publication System at Ministry of Health Hospitals in Saudi Arabia","authors":"Y. Alomi, S. Alghamdi, R. A. Alattyh","doi":"10.5530/amdhs.2018.1.5","DOIUrl":"https://doi.org/10.5530/amdhs.2018.1.5","url":null,"abstract":"Objective: To explore the National Survey of Drug Information Centers practice in Saudi Arabia: Research and Publications at MOH hospitals. Methods: It is a cross-sectional four months national survey of Drug Information Services at MOH. It contained ten domains with 181 questions designed by the authors. It was derived from Internal Pharmaceutical Federation, American Society of Health-System Pharmacists best practice guidelines. This survey was distributed to forty hospital pharmacies that run drug information services. In this study, the domain Research and Publications System was explored and analyzed. It consisted of eight questions about the written policy and procedure and application methods for Research and Publications at MOH system in the drug information centers. All analysis was done through survey monkey system. Results: The survey was distributed to 45 of hospitals, the response rate, was 40 (88.88%) hospitals. The highest score of investigational drug services was a written policy and procedure for IDS did not exist in 23 (57.5%) hospitals while only 6 (15%) of hospitals 100% applied the elements. The highest score of Pharmacy Professional Publications Services was the written policy and procedure for Professional Publications Services did not exist in 24 (60%) hospitals while only 6 (15%) of hospitals 100% applied the elements. The highest scores of Pharmacy Ethical and Legal Issues was a Written policy and procedure for Pharmacy Ethical and Legal did not exist in 20 (50%) hospitals while only 7 (17.5%) of hospitals 100% applied the elements. Conclusion: There was a weak implementation of Research and Publications system in drug information centers practice. An educating and training of drug information pharmacist on the Research and Publications system is required.in addition to setup up policy and procedures during the implementation of the services.","PeriodicalId":237766,"journal":{"name":"Advances in Medical, Dental and Health Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123713103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：