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Effectiveness of psychosocial interventions for pediatric patients with scoliosis: a systematic review. 儿童脊柱侧凸患者心理社会干预的有效性:一项系统综述。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-03-07 eCollection Date: 2023-01-01 DOI: 10.1136/wjps-2022-000513
Maike van Niekerk, Ann Richey, John Vorhies, Connie Wong, Kali Tileston

Background: Pediatric patients affected by scoliosis have complex psychological and social care needs, and may benefit from psychosocial interventions. We therefore aimed to summarize evidence of the efficacy of psychosocial interventions for this patient population.

Methods: Literature was identified by searching Medline, PsycINFO, Embase, EBSCO Cumulated Index to Nursing and Allied Health Literature (CINAHL), and Cochrane Central Register of Controlled Trials (CENTRAL) from database inception to 20 March 2022. Articles that evaluated the effectiveness of psychosocial interventions for pediatric patients diagnosed with scoliosis and reported at least one quantitative outcome were included. Article eligibility, data extraction, and quality assessment (using the Cochrane Collaboration's Risk of Bias Tool and Methodological Index for Non-Randomized Studies) were performed by two independent researchers. Findings are presented using narrative synthesis.

Results: We identified ten studies, all of which focused on adolescent idiopathic scoliosis. Studies included a total of 1007 participants, most of whom were female. Three studies focused on patients undergoing bracing, six on patients undergoing spinal surgery, and one on patients broadly. Brace compliance monitoring and counseling were found to significantly improve brace compliance quality and quantity. Proactive mental healthcare delivery by nurses after spinal surgery was similarly found to improve outcomes. Several studies examined the efficacy of brief educational interventions; most did not report clear evidence of their efficacy. The methodological quality of studies was often unclear due to limitations in articles' reporting quality.

Conclusions: Research on the efficacy of psychosocial interventions for pediatric patients with scoliosis is limited, with interventions involving frequent patient-provider interactions showing the most promise. Future clinical and research efforts should focus on developing and testing psychosocial interventions for this patient population, with emphasis on multidisciplinary teams delivering holistic care.

Trial registration number: PROSPERO number CRD42022326957.

背景:受脊柱侧弯影响的儿童患者有复杂的心理和社会护理需求,可能受益于心理社会干预。因此,我们旨在总结心理社会干预对该患者群体有效性的证据。方法:从数据库建立到2022年3月20日,通过检索Medline、PsycINFO、Embase、EBSCO护理和联合健康文献累积索引(CINAHL)和Cochrane对照试验中央登记册(Central)来识别文献。纳入了评估心理社会干预对诊断为脊柱侧弯的儿童患者的有效性并报告了至少一个定量结果的文章。文章资格、数据提取和质量评估(使用Cochrane协作的偏倚风险工具和非随机研究方法指数)由两名独立研究人员进行。研究结果采用叙述综合法呈现。结果:我们确定了10项研究,所有研究都集中在青少年特发性脊柱侧弯。研究共包括1007名参与者,其中大多数是女性。三项研究集中于接受支撑的患者,六项研究集中在接受脊柱手术的患者,一项研究广泛关注患者。支架依从性监测和咨询可显著提高支架依从性的质量和数量。同样,在脊柱手术后,护士提供积极的心理保健可以改善结果。几项研究考察了简短的教育干预措施的效果;大多数人没有报告明确的疗效证据。由于文章报告质量的限制,研究的方法质量往往不明确。结论:对儿童脊柱侧弯患者进行心理社会干预的疗效研究有限,涉及频繁的患者与提供者互动的干预措施最有希望。未来的临床和研究工作应侧重于为这一患者群体开发和测试心理社会干预措施,重点是提供整体护理的多学科团队。试验注册号:PROSPERO编号CRD42022326957。
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引用次数: 1
Tribute to reviewers (January 1, 2022 to December 31, 2022) 向审稿人致敬(2022年1月1日至2022年12月31日)
4区 医学 Q4 PEDIATRICS Pub Date : 2023-03-01 DOI: 10.1136/wjps-2023-reviewers
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引用次数: 0
Outcomes of two-stage double-level rotational osteotomy in treating patients with congenital proximal radioulnar synostosis. 两阶段双水平旋转截骨术治疗先天性尺桡近端关节闭锁的疗效。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-01-01 DOI: 10.1136/wjps-2023-000578
Hu Bo, Jingfang Xu, Jianlan Lin, Weiwei Zhu, Zhefeng Zhen, Wensong Ye, Wenhao Chen
Department of Orthopedics, Sir Run Run Hospital Nanjing Medical University, Nanjing, Jiangsu, China Department of Orthopedics, Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China Department of Orthopedics, Fujian Children’s Hospital, Fuzhou, Fujian Province, China Department of Pediatric Surgery, Fujian Maternity and Child Health Hospital, Fuzhou, Fujian, China
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引用次数: 0
Radiomic-based machine learning model for predicting the surgical risk in children with abdominal neuroblastoma. 基于放射组学的机器学习模型预测腹部神经母细胞瘤儿童手术风险。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-01-01 DOI: 10.1136/wjps-2022-000531
Xuan Jia, Jiawei Liang, Xiaohui Ma, Wenqi Wang, Can Lai

Background: Preoperative imaging assessment of surgical risk is very important for the prognosis of these children. To develop and validate a radiomics-based machine learning model based on the analysis of radiomics features to predict surgical risk in children with abdominal neuroblastoma (NB).

Methods: A retrospective study was conducted from April 2019 to March 2021 among 74 children with abdominal NB. A total of 1874 radiomic features in MR images were extracted from each patient. Support vector machines (SVMs) were used to establish the model. Eighty percent of the data were used as the training set to optimize the model, and 20% of the data were used to validate its accuracy, sensitivity, specificity and area under the curve (AUC) to verify its effectiveness.

Results: Among the 74 children with abdominal NB, 55 (65%) had surgical risk and 19 (35%) had no surgical risk. A t test and Lasso identified that 28 radiomic features were associated with surgical risk. After developing an SVM-based model using these features, predictions were made about whether children with abdominal NB had surgical risk. The model achieved an AUC of 0.94 (a sensitivity of 0.83 and a specificity of 0.80) with 0.890 accuracy in the training set and an AUC of 0.81 (a sensitivity of 0.73 and a specificity of 0.82) with 0.838 accuracy in the test set.

Conclusions: Radiomics and machine learning can be used to predict the surgical risk in children with abdominal NB. The model based on 28 radiomic features established by SVM showed good diagnostic efficiency.

背景:术前影像学评估手术风险对这些患儿的预后非常重要。开发并验证基于放射组学特征分析的基于放射组学的机器学习模型,以预测腹部神经母细胞瘤(NB)儿童的手术风险。方法:对2019年4月至2021年3月74例腹部NB患儿进行回顾性研究。从每位患者的MR图像中提取了1874个放射学特征。采用支持向量机(svm)建立模型。80%的数据作为训练集用于优化模型,20%的数据用于验证模型的准确性、灵敏度、特异性和曲线下面积(AUC),以验证模型的有效性。结果:74例腹部NB患儿中,55例(65%)存在手术风险,19例(35%)无手术风险。t检验和Lasso确定了28个放射学特征与手术风险相关。在利用这些特征开发了基于svm的模型后,对腹部NB患儿是否有手术风险进行了预测。该模型在训练集中的AUC为0.94(灵敏度为0.83,特异性为0.80),准确率为0.890;在测试集中的AUC为0.81(灵敏度为0.73,特异性为0.82),准确率为0.838。结论:放射组学和机器学习可用于预测腹部NB患儿的手术风险。基于支持向量机建立的28个放射学特征模型具有较好的诊断效果。
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引用次数: 0
Cases of pediatric intra-abdominal solid organ injury induced by blunt trauma experienced over a 15-year period at two centers in Japan. 在日本的两个中心,儿童钝性创伤引起的腹腔内实体器官损伤的病例经历了15年的时间。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-01-01 DOI: 10.1136/wjps-2023-000560
Mayu Matsui, Koshiro Sugita, Takafumi Kawano, Nanako Nishida, Ayaka Nagano, Masakazu Murakami, Keisuke Yano, Toshio Harumatsu, Shun Onishi, Koji Yamada, Waka Yamada, Mitsuru Muto, Tatsuru Kaji, Satoshi Ieiri

Objective: The present study attempts to clarify the clinical features of pediatric intra-abdominal solid organ injury at two institutions.

Methods: The injured organ, patient age, sex, injury grade, imaging findings, intervention, length of hospital stay, and complications were retrospectively reviewed using medical records at two centers from 2007 to 2021.

Results: There were 25 cases of liver injury, 9 of splenic injury, 8 of pancreatic injury, and 5 of renal injury. The mean age of all patients was 8.6±3.8 years old, with no difference between organ injury types. Radiological intervention was performed in four cases of liver injury (16.0%) and one case of splenic injury (11.1%), and surgery was performed in two cases of liver injury (8.0%) and three cases of pancreatic injury (37.5%). All other cases were treated conservatively. Complications included adhesive ileus in one case of liver injury (4.0%), splenic atrophy in one case of splenic injury (11.1%), pseudocysts in three cases of pancreatic injury (37.5%), atrophy of the pancreatic parenchyma in one case of pancreatic injury (12.5%), and urinoma in one case of renal injury (20.0%). No mortalities were observed.

Conclusion: Pediatric patients with blunt trauma had favorable outcomes at two pediatric trauma centers covering a broad medical area, including remote islands.

目的:本研究试图阐明两所医院小儿腹腔内实体器官损伤的临床特点。方法:回顾性分析两个中心2007 - 2021年的病历资料,包括损伤器官、患者年龄、性别、损伤等级、影像学表现、干预措施、住院时间和并发症。结果:肝损伤25例,脾损伤9例,胰损伤8例,肾损伤5例。所有患者的平均年龄为8.6±3.8岁,器官损伤类型无差异。肝损伤4例(16.0%)、脾损伤1例(11.1%)行放射干预,肝损伤2例(8.0%)、胰腺损伤3例(37.5%)行手术治疗。其余病例均采用保守治疗。并发症包括肝损伤1例粘连性肠梗阻(4.0%),脾损伤1例脾萎缩(11.1%),胰腺损伤3例假性囊肿(37.5%),胰腺损伤1例胰腺实质萎缩(12.5%),肾损伤1例尿液瘤(20.0%)。未观察到死亡。结论:两家儿科创伤中心覆盖了广泛的医疗区域,包括偏远的岛屿,钝性创伤的儿童患者预后良好。
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引用次数: 0
Epigastric hernias in children and the use of ultrasound in its diagnosis. 儿童腹壁疝及其超声诊断的应用。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-01-01 DOI: 10.1136/wjps-2022-000544
Tatjana T König, Laura S Oerters, Ljuba Spiller, Martin Schwind, Mark Born, Christina Oetzmann von Sochaczewski, Andreas C Heydweiller

Introduction: There is a paucity of clinical data on pediatric epigastric hernias despite them accounting for up to 6% of all hernia repairs in children. We aimed to provide additional data to supplement those 117 cases of a recent systematic review and to further clarify the role of ultrasound in diagnosing pediatric epigastric hernia.

Methods: We retrospectively included all 60 patients treated for epigastric hernias in children in two tertiary pediatric surgical departments within 12 years. Associations were tested via point-biserial correlation analyses.

Results: Epigastric hernias primarily affected preschool children with a median age of 39 months. The vast majority of patients (88%) presented with swelling that was occasionally (30%) accompanied by pain. Fascial defects could be found during clinical examination in 45% of patients with a median size of 5 mm (95% CI 3 to 10). Smaller defects were less likely to be palpable (r=-0.44, 95% CI -0.08 to -0.7, p=0.021). Likewise, ultrasound was used more frequently with smaller fascial defect sizes (r=-0.51, 95% CI -0.16 to -0.74, p=0.007). Laparoscopic repair was used in 11 patients (19%) and more often (4/11) in combination with another simultaneous procedure than open repair (11/48).

Conclusions: Epigastric hernias are primarily a condition of the preschool child. Ultrasound can be beneficial if the diagnosis cannot be made clinically; otherwise, it is abdicable if it does not change the management of the patient's epigastric hernia. Laparoscopic repairs might be beneficial for children with multiple defects or simultaneous procedures.

导读:尽管儿童腹壁疝占所有儿童疝修补术的6%,但关于儿童腹壁疝的临床数据缺乏。我们的目的是提供额外的数据来补充这117例最近的系统回顾,并进一步阐明超声在诊断小儿腹壁疝中的作用。方法:我们回顾性地纳入了12年内在两个三级儿科外科治疗的60例儿童上腹部疝患者。通过点双列相关分析检验相关性。结果:上腹部疝主要影响学龄前儿童,中位年龄为39个月。绝大多数患者(88%)表现为肿胀,偶尔(30%)伴有疼痛。45%的患者在临床检查中发现筋膜缺损,中位尺寸为5mm (95% CI 3 ~ 10)。较小的缺陷不太可能被发现(r=-0.44, 95% CI -0.08至-0.7,p=0.021)。同样,超声在筋膜缺损较小的情况下使用频率更高(r=-0.51, 95% CI -0.16 ~ -0.74, p=0.007)。11例患者(19%)采用腹腔镜修复,与其他同步手术(11/48)相比,更多的患者(4/11)采用腹腔镜修复。结论:腹壁疝主要是学龄前儿童的一种疾病。如果不能临床诊断,超声是有益的;否则,如果它不改变病人腹壁疝的治疗,它是可取的。腹腔镜修复可能有利于儿童多缺陷或同时手术。
{"title":"Epigastric hernias in children and the use of ultrasound in its diagnosis.","authors":"Tatjana T König,&nbsp;Laura S Oerters,&nbsp;Ljuba Spiller,&nbsp;Martin Schwind,&nbsp;Mark Born,&nbsp;Christina Oetzmann von Sochaczewski,&nbsp;Andreas C Heydweiller","doi":"10.1136/wjps-2022-000544","DOIUrl":"https://doi.org/10.1136/wjps-2022-000544","url":null,"abstract":"<p><strong>Introduction: </strong>There is a paucity of clinical data on pediatric epigastric hernias despite them accounting for up to 6% of all hernia repairs in children. We aimed to provide additional data to supplement those 117 cases of a recent systematic review and to further clarify the role of ultrasound in diagnosing pediatric epigastric hernia.</p><p><strong>Methods: </strong>We retrospectively included all 60 patients treated for epigastric hernias in children in two tertiary pediatric surgical departments within 12 years. Associations were tested via point-biserial correlation analyses.</p><p><strong>Results: </strong>Epigastric hernias primarily affected preschool children with a median age of 39 months. The vast majority of patients (88%) presented with swelling that was occasionally (30%) accompanied by pain. Fascial defects could be found during clinical examination in 45% of patients with a median size of 5 mm (95% CI 3 to 10). Smaller defects were less likely to be palpable (r=-0.44, 95% CI -0.08 to -0.7, p=0.021). Likewise, ultrasound was used more frequently with smaller fascial defect sizes (r=-0.51, 95% CI -0.16 to -0.74, p=0.007). Laparoscopic repair was used in 11 patients (19%) and more often (4/11) in combination with another simultaneous procedure than open repair (11/48).</p><p><strong>Conclusions: </strong>Epigastric hernias are primarily a condition of the preschool child. Ultrasound can be beneficial if the diagnosis cannot be made clinically; otherwise, it is abdicable if it does not change the management of the patient's epigastric hernia. Laparoscopic repairs might be beneficial for children with multiple defects or simultaneous procedures.</p>","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":"6 2","pages":"e000544"},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9b/61/wjps-2022-000544.PMC10083873.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9304961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Association between high deductible health plan coverage and age at pediatric umbilical hernia repair. 高免赔额健康计划覆盖率与儿童脐疝修补年龄之间的关系。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-01-01 DOI: 10.1136/wjps-2022-000526
Morgan E Doty, Lindsay A Gil, Jennifer N Cooper

Background: High deductible health plans (HDHPs) are associated with the avoidance of both necessary and unnecessary healthcare. Umbilical hernia repair (UHR) is a procedure that is frequently unnecessarily performed in young children, contrary to best practice guidelines. We hypothesized that children with HDHPs, as compared with other types of commercial health plans, are less likely to undergo UHR before 4 years of age but are also more likely to have UHR delayed beyond 5 years of age.

Methods: Children aged 0-18 years old residing in metropolitan statistical areas (MSAs) who underwent UHR in 2012-2019 were identified in the IBM Marketscan Commercial Claims and Encounters Database. A quasi-experimental study design using MSA/year-level HDHP prevalence among children as an instrumental variable was employed to account for selection bias in HDHP enrollment. Two-stage least squares regression modeling was used to evaluate the association between HDHP coverage and age at UHR.

Results: A total of 8601 children were included (median age 5 years, IQR 3-7). Univariable analysis revealed no differences between the HDHP and non-HDHP groups in the likelihood of UHR being performed before 4 years of age (27.7% vs 28.7%, p=0.37) or after 5 years of age (39.8% vs 38.9%, p=0.52). Geographical region, metropolitan area size, and year were associated with HDHP enrollment. Instrumental variable analysis demonstrated no association between HDHP coverage and undergoing UHR at <4 years of age (p=0.76) or >5 years of age (p=0.87).

Conclusions: HDHP coverage is not associated with age at pediatric UHR. Future studies should investigate other means by which UHRs in young children can be avoided.

背景:高免赔额健康计划(HDHPs)与避免必要和不必要的医疗保健有关。脐疝修补术(UHR)是一种经常在幼儿中进行的不必要的手术,违背了最佳实践指南。我们假设,与其他类型的商业健康计划相比,患有hdhp的儿童在4岁之前接受UHR的可能性较小,但UHR延迟到5岁以后的可能性也更大。方法:在IBM Marketscan商业索赔和遭遇数据库中确定2012-2019年居住在大都市统计区(msa)的0-18岁儿童。采用准实验研究设计,将儿童中MSA/年度水平HDHP患病率作为工具变量,以解释HDHP入组的选择偏倚。采用两阶段最小二乘回归模型评估HDHP覆盖率与UHR年龄之间的关系。结果:共纳入8601例儿童(中位年龄5岁,IQR 3-7)。单变量分析显示,HDHP组和非HDHP组在4岁前(27.7% vs 28.7%, p=0.37)或5岁后(39.8% vs 38.9%, p=0.52)进行UHR的可能性没有差异。地理区域、大都市区大小和年份与HDHP注册人数有关。工具变量分析显示,HDHP覆盖率与5岁时接受UHR没有关联(p=0.87)。结论:HDHP覆盖率与儿童UHR的年龄无关。未来的研究应探讨避免幼儿超高辐射的其他方法。
{"title":"Association between high deductible health plan coverage and age at pediatric umbilical hernia repair.","authors":"Morgan E Doty,&nbsp;Lindsay A Gil,&nbsp;Jennifer N Cooper","doi":"10.1136/wjps-2022-000526","DOIUrl":"https://doi.org/10.1136/wjps-2022-000526","url":null,"abstract":"<p><strong>Background: </strong>High deductible health plans (HDHPs) are associated with the avoidance of both necessary and unnecessary healthcare. Umbilical hernia repair (UHR) is a procedure that is frequently unnecessarily performed in young children, contrary to best practice guidelines. We hypothesized that children with HDHPs, as compared with other types of commercial health plans, are less likely to undergo UHR before 4 years of age but are also more likely to have UHR delayed beyond 5 years of age.</p><p><strong>Methods: </strong>Children aged 0-18 years old residing in metropolitan statistical areas (MSAs) who underwent UHR in 2012-2019 were identified in the IBM Marketscan Commercial Claims and Encounters Database. A quasi-experimental study design using MSA/year-level HDHP prevalence among children as an instrumental variable was employed to account for selection bias in HDHP enrollment. Two-stage least squares regression modeling was used to evaluate the association between HDHP coverage and age at UHR.</p><p><strong>Results: </strong>A total of 8601 children were included (median age 5 years, IQR 3-7). Univariable analysis revealed no differences between the HDHP and non-HDHP groups in the likelihood of UHR being performed before 4 years of age (27.7% vs 28.7%, p=0.37) or after 5 years of age (39.8% vs 38.9%, p=0.52). Geographical region, metropolitan area size, and year were associated with HDHP enrollment. Instrumental variable analysis demonstrated no association between HDHP coverage and undergoing UHR at <4 years of age (p=0.76) or >5 years of age (p=0.87).</p><p><strong>Conclusions: </strong>HDHP coverage is not associated with age at pediatric UHR. Future studies should investigate other means by which UHRs in young children can be avoided.</p>","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":"6 2","pages":"e000526"},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/82/wjps-2022-000526.PMC10030914.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9561093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Umbilical cord sparing technique of umbilicoplasty in infants with giant omphalocele. 巨大脐膨出婴儿脐带成形术中的保留脐带技术。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-01-01 DOI: 10.1136/wjps-2023-000574
Peng Wang, Jinfa Tou
{"title":"Umbilical cord sparing technique of umbilicoplasty in infants with giant omphalocele.","authors":"Peng Wang,&nbsp;Jinfa Tou","doi":"10.1136/wjps-2023-000574","DOIUrl":"https://doi.org/10.1136/wjps-2023-000574","url":null,"abstract":"","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":"6 3","pages":"e000574"},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9817452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digestive perianastomotic ulcerations after intestinal resection in children. 儿童肠切除术后消化道吻合口周围溃疡。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-01-01 DOI: 10.1136/wjps-2022-000533
Weicheng Zhang, Jinfa Tou

Digestive perianastomotic ulceration (DPAU) is a rare complication after intestinal resection and anastomosis occurring at or near the anastomosis site. The purpose of this review is to summarize the characteristics of DPAU, including the etiology, diagnosis and differential diagnosis, clinical manifestations, treatment, and future research. All recent literature on DPAU was searched in PubMed, Embase, and Cochrane and then reviewed. The clinical manifestations of DPAU are mainly gastrointestinal symptoms such as bloody stool and chronic anemia. The diagnosis of DPAU is difficult. Specific diseases, such as Crohn's disease, must be ruled out before a diagnosis can be made. In addition, there are no clear treatment guidelines due to the high degree of heterogeneity in response to drugs and surgery. It is recommended to adjust medication in time and combine various treatment methods. In addition, the mechanism that causes DPAU is not well understood; however, several possible mechanisms have been proposed, such as scar tissue ischemia and underlying diseases. Moreover, there is a high risk of relapses, and a long-term follow-up is necessary. Numerous issues remain to be solved in this area; therefore, more randomized controlled trials and studies should be carried out to further understand this disease.

消化道吻合口周围溃疡(DPAU)是肠切除术吻合后发生在吻合部位或附近的罕见并发症。本文综述DPAU的特点,包括病因、诊断与鉴别诊断、临床表现、治疗方法及未来研究方向。在PubMed, Embase和Cochrane中检索了所有关于DPAU的最新文献,然后进行了回顾。DPAU的临床表现以大便带血、慢性贫血等胃肠道症状为主。诊断DPAU是困难的。特定疾病,如克罗恩病,必须在诊断之前排除。此外,由于对药物和手术反应的高度异质性,尚无明确的治疗指南。建议及时调整用药,并结合多种治疗方法。此外,导致DPAU的机制尚不清楚;然而,已经提出了几种可能的机制,如疤痕组织缺血和潜在疾病。此外,复发风险高,需要长期随访。在这方面仍有许多问题有待解决;因此,需要开展更多的随机对照试验和研究来进一步了解这种疾病。
{"title":"Digestive perianastomotic ulcerations after intestinal resection in children.","authors":"Weicheng Zhang,&nbsp;Jinfa Tou","doi":"10.1136/wjps-2022-000533","DOIUrl":"https://doi.org/10.1136/wjps-2022-000533","url":null,"abstract":"<p><p>Digestive perianastomotic ulceration (DPAU) is a rare complication after intestinal resection and anastomosis occurring at or near the anastomosis site. The purpose of this review is to summarize the characteristics of DPAU, including the etiology, diagnosis and differential diagnosis, clinical manifestations, treatment, and future research. All recent literature on DPAU was searched in PubMed, Embase, and Cochrane and then reviewed. The clinical manifestations of DPAU are mainly gastrointestinal symptoms such as bloody stool and chronic anemia. The diagnosis of DPAU is difficult. Specific diseases, such as Crohn's disease, must be ruled out before a diagnosis can be made. In addition, there are no clear treatment guidelines due to the high degree of heterogeneity in response to drugs and surgery. It is recommended to adjust medication in time and combine various treatment methods. In addition, the mechanism that causes DPAU is not well understood; however, several possible mechanisms have been proposed, such as scar tissue ischemia and underlying diseases. Moreover, there is a high risk of relapses, and a long-term follow-up is necessary. Numerous issues remain to be solved in this area; therefore, more randomized controlled trials and studies should be carried out to further understand this disease.</p>","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":"6 3","pages":"e000533"},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/f6/wjps-2022-000533.PMC10410847.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10033144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of pediatric ventriculo-peritoneal shunt infections arising in antibiotic-impregnated and standard catheters: a multicenter observational study. 抗生素浸渍和标准导管引起的儿科脑室-腹膜分流感染的比较:一项多中心观察性研究。
IF 0.8 4区 医学 Q4 PEDIATRICS Pub Date : 2023-01-01 DOI: 10.1136/wjps-2023-000566
Joan Robinson, Archana Balamohan, Michelle Barton, Marie-Astrid Lefebvre, Ahmed Almadani, Dolores Freire, Alastair McAlpine, Jocelyn Srigley, Patrick Passarelli, John Bradley, Dele Davies, Gwenn Skar, Isabelle Viel-Theriault, Sarah Khan, Rupeena Purewal, Nicole LeSaux, Jennifer Bowes, Michael Hawkes
Antibiotic-impregnated ventricular shunt catheters
{"title":"Comparison of pediatric ventriculo-peritoneal shunt infections arising in antibiotic-impregnated and standard catheters: a multicenter observational study.","authors":"Joan Robinson,&nbsp;Archana Balamohan,&nbsp;Michelle Barton,&nbsp;Marie-Astrid Lefebvre,&nbsp;Ahmed Almadani,&nbsp;Dolores Freire,&nbsp;Alastair McAlpine,&nbsp;Jocelyn Srigley,&nbsp;Patrick Passarelli,&nbsp;John Bradley,&nbsp;Dele Davies,&nbsp;Gwenn Skar,&nbsp;Isabelle Viel-Theriault,&nbsp;Sarah Khan,&nbsp;Rupeena Purewal,&nbsp;Nicole LeSaux,&nbsp;Jennifer Bowes,&nbsp;Michael Hawkes","doi":"10.1136/wjps-2023-000566","DOIUrl":"https://doi.org/10.1136/wjps-2023-000566","url":null,"abstract":"Antibiotic-impregnated ventricular shunt catheters","PeriodicalId":23823,"journal":{"name":"World Journal of Pediatric Surgery","volume":"6 3","pages":"e000566"},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/60/wjps-2023-000566.PMC10410850.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10033145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
World Journal of Pediatric Surgery
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