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Bessel's disease-the first report of an IgG4-related disorder. 贝塞尔氏病--首次报道与 IgG4 相关的疾病。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-18 DOI: 10.1007/s00393-024-01502-1
B. Manger, G. Schett
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引用次数: 0
[Fever in rheumatological diseases]. [风湿病中的发热]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-18 DOI: 10.1007/s00393-024-01505-y
Jasper F. Nies, Martin Krusche
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引用次数: 0
[Laboratory diagnostics for vasculitis beyond antineutrophil cytoplasmatic autoantibodies]. [抗中性粒细胞胞浆自身抗体之外的脉管炎实验室诊断]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-08 DOI: 10.1007/s00393-024-01494-y
Ulf Schönermarck, Bernhard Hellmich, E. Csernok
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引用次数: 0
[Current data on rheumatological care: annual report from the National database (NDB) of the regional collaborative arthritis centres in Germany]. [风湿病治疗的最新数据:德国地区关节炎协作中心国家数据库(NDB)年度报告]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-03 DOI: 10.1007/s00393-024-01497-9
K. Albrecht, Katja Thiele, Tobias Alexander, Martin Aringer, Thorsten Eidner, Jörg Henes, G. Hoese, Kirsten Karberg, U. Kiltz, Andreas Krause, Wolfgang Ochs, Jutta G. Richter, Susanna Späthling-Mestekemper, Mirko Steinmüller, Siegfried Wassenberg, A. Strangfeld, J. Callhoff
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引用次数: 0
[The effect of intensified training therapy on axial spondylarthritis in day care units]. [强化训练疗法对日间护理单位轴性脊柱关节炎的影响]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2023-03-09 DOI: 10.1007/s00393-023-01333-6
T Schneidereit, D Delia, T Schmeiser, B Buehring

Background: Day care units are an essential part of psychiatric treatment in Germany. In rheumatology they are also regularly used. Axial spondylarthritis (axSpA) is an inflammatory rheumatic disease that causes pain, diminished quality of life, limitations in activities of daily living and ability to work, especially if insufficiently treated. The multimodal rheumatologic complex treatment with at least 14 days of inpatient care is an established tool to control exacerbated disease activity. The feasibility and effect of an equivalent treatment in a day care setting has not yet been evaluated.

Methods: The effect of a therapy in a day care unit comparable to the inpatient multimodal rheumatologic complex treatment was investigated using clinically established patient reported outcomes (NAS pain, FFbH, BASDAI, BASFI).

Results: Selected subgroups of axSpA patients can routinely and effectively be treated in day care units. Intensified multimodal as well as nonintensified treatment forms lead to reduced disease activity. Additionally, compared to nonintensified treatment, the intensified multimodal treatment approach leads to significantly reduced pain, and disease-related and functional limitations in daily life.

Conclusion: If available, treatment in a day care unit can complement the established inpatient treatment modalities in selected axSpA patients. In cases with high disease activity and suffering, intensified multimodal treatment should be preferred due to better outcomes.

背景介绍在德国,日间护理病房是精神病治疗的重要组成部分。在风湿病学领域也经常使用。轴性脊椎关节炎(axSpA)是一种炎症性风湿病,会导致疼痛、生活质量下降、日常生活和工作能力受限,尤其是在治疗不充分的情况下。住院治疗至少 14 天的多模式风湿病综合治疗是控制疾病活动加剧的既定工具。在日间护理环境中进行同等治疗的可行性和效果尚未得到评估:日间护理病房的治疗效果可与住院多模式风湿病综合治疗相媲美,研究采用了临床公认的患者报告结果(NAS 疼痛、FFbH、BASDAI、BASFI):结果:日间护理病房可对特定亚组 axSpA 患者进行常规、有效的治疗。多模式强化治疗和非强化治疗均可减少疾病活动。此外,与非强化治疗相比,强化多模式治疗方法可显著减少疼痛、与疾病相关的日常生活功能限制:结论:如果条件允许,日间护理病房的治疗可以对选定的axSpA患者的住院治疗模式起到补充作用。对于疾病活动度高、痛苦大的病例,应首选强化多模式治疗,以获得更好的疗效。
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引用次数: 0
["Rheuma (be-)greifen"- A multimodal teaching concept to improve rheumatology education for medical students]. [Rheuma (be-)greifen" - 改进医科学生风湿病学教育的多模式教学理念]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2023-07-28 DOI: 10.1007/s00393-023-01391-w
L Schuster, L Valor-Méndez, J Wacker, V Dannhardt-Thiem, A Schmidt, J Knitza, D Simon, B Manger, G Schett, A Kleyer

Background: The German Society for Rheumatology, through its campaign Rheuma2025, aims to improve student teaching in order to ensure patient care for rheumatological patients in the future.

Objective: To assess whether a combination of traditional and innovative educational methods provide both an improvement in the quality of teaching and an increase in the attractiveness of rheumatology as a discipline.

Material and methods: Establishment of the teaching concept "Rheuma (be-)greifen" consisting of five modules on patient history taking with acting patients, musculoskeletal ultrasound, arthrocentesis, 3D printing of pathological joints and virtual reality applications based on real patient cases in the curricular teaching of medical students.

Results: The evaluation of the teaching concept with 93 students of medicine showed a consistently high acceptance of all modules, which were rated as very effective or rather effective. Direct patient-related modules, such as history taking with acting patients, musculoskeletal ultrasound and arthrocentesis, received even higher acceptance than the visualization methods utilizing 3D printing and virtual reality.

Conclusion: Innovative teaching methods can help to improve the acceptance of teaching in the field of rheumatology, especially when combined with classical teaching contents.

背景:德国风湿病学会(German Society for Rheumatology)通过其 "Rheuma2025 "运动,旨在提高学生的教学水平,以确保未来对风湿病患者的护理:评估传统和创新教育方法的结合是否既能提高教学质量,又能增加风湿病学作为一门学科的吸引力:建立 "Rheuma (be-)greifen "教学理念,该理念由五个模块组成,分别是在医科学生的课程教学中以真实患者病例为基础的病史采集、肌肉骨骼超声波检查、关节穿刺术、病理关节3D打印和虚拟现实应用:结果:93 名医科学生对教学理念的评估表明,他们对所有模块的接受度都很高,认为这些模块非常有效或相当有效。与病人直接相关的模块,如与表演病人一起采集病史、肌肉骨骼超声波检查和关节穿刺术,比利用 3D 打印和虚拟现实技术的可视化方法获得了更高的认可度:创新教学方法有助于提高风湿病学领域教学的接受度,尤其是与经典教学内容相结合时。
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引用次数: 0
[Immune-mediated inflammatory diseases in Germany : A cross-sectional analysis of comorbidities and pharmacotherapy]. [德国免疫介导的炎症性疾病:合并症和药物治疗的横断面分析]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2023-01-04 DOI: 10.1007/s00393-022-01306-1
Jan Leipe, Renate Schmelz, Gabriela Riemekasten, Diamant Thaçi, Jörg Henes, Knut Schäkel, Andreas Pinter, Michael Sticherling, Joanna Wegner, Stefano Fusco, Miriam Linke, Valeria Weber, Karina C Manz, Holger Bartz, Marit Roecken, Sandra Schmidt, Bimba F Hoyer

Background: Immune-mediated inflammatory diseases (IMID) can lead to a substantial disease burden for those affected, in particular by the concomitant occurrence of other IMIDs or in the presence of comorbidities. The care of patients with IMIDs is complex and involves various medical disciplines.

Objective: To describe the burden of disease and the current routine drug treatment of patients with IMID.

Material and methods: The retrospective cross-sectional analysis was based on statutory health insurance claims data from the InGef database. Prevalent patients with psoriasis (Pso), psoriatic arthritis (PsA), spondylarthritis (SpA), rheumatoid arthritis (RA), Crohn's disease (MC), ulcerative colitis (CU), or connective tissue disease were identified among 3,988,695 insured patients in 2018. The concomitant occurrence of different IMIDs and the extent to which patients with IMID are affected by other comorbidities compared to a reference population were investigated. The current routine drug treatment was described based on the use of predefined forms of treatment.

Results: In the database 188,440 patients with IMID (4.7%) were identified. Compared to the reference population the prevalence of comorbidities, such as depressive episodes and cardiovascular risk factors was higher in patients with IMID. For MC, CU, RA, and PsA disease-modifying antirheumatic drugs (DMARD) and classical systemic forms of treatment were used most commonly. In Pso, SpA, and connective tissue disease nonsteroidal anti-inflammatory drugs (NSAID) were the most frequently used treatment often in combination with other drugs.

Conclusion: A considerable number of patients with IMIDs (16.9-27.5%) suffer from different diseases of the IMID group. They are frequently affected by accompanying illnesses and require interdisciplinary medical treatment.

背景:免疫介导的炎症性疾病(IMID)会给患者带来沉重的疾病负担,尤其是同时患有其他 IMID 或合并症的患者。IMID 患者的护理工作十分复杂,涉及多个医学学科:材料与方法:回顾性横断面分析基于 InGef 数据库中的法定医疗保险理赔数据。在2018年的3,988,695名参保患者中确定了银屑病(Pso)、银屑病关节炎(PsA)、脊柱关节炎(SpA)、类风湿性关节炎(RA)、克罗恩病(MC)、溃疡性结肠炎(CU)或结缔组织病的患病率。与参照人群相比,调查了不同 IMID 的并发情况以及 IMID 患者受其他合并症影响的程度。在使用预定义治疗形式的基础上,对当前的常规药物治疗进行了描述:在数据库中发现了 188440 名 IMID 患者(4.7%)。与参照人群相比,IMID 患者的合并症发病率更高,如抑郁发作和心血管风险因素。对于 MC、CU、RA 和 PsA,最常用的是改善病情抗风湿药物(DMARD)和传统的系统治疗方法。在Pso、SpA和结缔组织病中,非甾体抗炎药(NSAID)是最常用的治疗方法,通常与其他药物联合使用:结论:相当多的 IMIDs 患者(16.9%-27.5%)患有不同的 IMID 类疾病。他们经常受到伴随疾病的影响,需要接受跨学科的治疗。
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引用次数: 0
[Update on Sjögren's syndrome : Diagnostics, treatment, and challenges]. [斯约格伦综合征的最新进展:诊断、治疗和挑战]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2024-03-18 DOI: 10.1007/s00393-024-01493-z
Nadine Zehrfeld, Torsten Witte, Diana Ernst

Sjögren's syndrome (SjS) is the most common connective tissue disease with a prevalence of 1:200. Predominantly affecting women, SjS is associated with destruction of the exocrine glands, leading to xerophthalmia and xerostomia. In over 50% of patients, there are also extraglandular manifestations, leading to multiple organ manifestations including polyneuropathies and interstitial lung disease as well as symptoms such as fatigue and arthralgia. Diagnostic procedures include biomarkers, in particular anti-SS-A/Ro antibodies, histology of salivary glands, and salivary gland sonography. There are currently no licensed immunosuppressive drugs for SjS, so current treatment is often based on off-label use of drugs. The European League Against Rheumatism (EULAR) has recently published treatment recommendations based on the prevailing organ manifestations. Several promising controlled trials with novel compounds and concepts are currently in progress.

斯约格伦综合征(Sjögren's syndrome,SjS)是最常见的结缔组织病,发病率为 1:200。SjS 主要影响女性,与外分泌腺的破坏有关,导致眼干症和口干症。50%以上的患者还伴有腺体外表现,导致多器官表现,包括多发性神经病和间质性肺病,以及疲劳和关节痛等症状。诊断程序包括生物标志物,尤其是抗 SS-A/Ro 抗体、唾液腺组织学检查和唾液腺超声检查。目前还没有针对 SjS 的特许免疫抑制剂,因此目前的治疗通常是在标签外使用药物。欧洲抗风湿病联盟(EULAR)最近发布了基于主要器官表现的治疗建议。目前,几项采用新型化合物和概念的对照试验正在进行中,前景看好。
{"title":"[Update on Sjögren's syndrome : Diagnostics, treatment, and challenges].","authors":"Nadine Zehrfeld, Torsten Witte, Diana Ernst","doi":"10.1007/s00393-024-01493-z","DOIUrl":"10.1007/s00393-024-01493-z","url":null,"abstract":"<p><p>Sjögren's syndrome (SjS) is the most common connective tissue disease with a prevalence of 1:200. Predominantly affecting women, SjS is associated with destruction of the exocrine glands, leading to xerophthalmia and xerostomia. In over 50% of patients, there are also extraglandular manifestations, leading to multiple organ manifestations including polyneuropathies and interstitial lung disease as well as symptoms such as fatigue and arthralgia. Diagnostic procedures include biomarkers, in particular anti-SS-A/Ro antibodies, histology of salivary glands, and salivary gland sonography. There are currently no licensed immunosuppressive drugs for SjS, so current treatment is often based on off-label use of drugs. The European League Against Rheumatism (EULAR) has recently published treatment recommendations based on the prevailing organ manifestations. Several promising controlled trials with novel compounds and concepts are currently in progress.</p>","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Positive experiences of specialist assistants and physicians with respect to the delegation research project StaerkeR : Evaluation of the training and experiences within the framework of this project]. [专家助理和医生在委托研究项目 "StaerkeR:项目框架内的培训和经验评估 "中的积极经验]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2022-12-09 DOI: 10.1007/s00393-022-01298-y
Anna Mai, Sandra Abrantes Diaz, Michelle Stein, Robin Denz, Renate Klaaßen-Mielke, Nina Timmesfeld, Dietmar Krause, Jürgen Braun

Introduction: The delegation of medical services to rheumatology assistants (RFA) has proven to be safe and effective in the evaluation of the research project "StaerkeR". Afterwards, the experiences of the participating RFAs and rheumatologists with delegation were surveyed and discussed within the framework of an opinion research project.

Methods: At the end of the project, the participating RFAs and rheumatologists were surveyed via an online questionnaire (quantitative analysis) (21 questions for physicians and 44 questions for RFAs). In addition, focus group meetings were held for the RFAs, which were led by a moderator and a secretary. The results of the focus group sessions (qualitative analyses) were analyzed according to the structured method of Kuckartz.

Results: All 31 RFAs and 25 rheumatologists involved in the project participated in the online surveys and 9 RFAs took part in the 2 focus groups. In the online surveys, both the RFAs and the rheumatologists gave predominantly good to very good ratings with respect to RFA training, the implementation of delegation in the practices and outpatient clinics, the role of the RFAs and the overall evaluation of the delegation concept. In the focus group discussions, many possible limitations regarding acceptance and implementation of the delegation concept were mentioned.

Conclusion: The delegation of medical tasks to RFAs is a concept that is positively assessed and highly accepted by both sides, the rheumatologists and the RFAs. In a comparison between the individual practices and hospital outpatient departments, there is still a clear heterogeneity with respect to the willingness and logistical possibilities in the implementation of the delegation concept.

导言:在 "StaerkeR "研究项目的评估中,将医疗服务委托给风湿病学助理(RFA)被证明是安全有效的。随后,在民意调查项目的框架内,对参与项目的风湿病学助理和风湿病学专家的委托经验进行了调查和讨论:在项目结束时,通过在线问卷(定量分析)(针对医生的 21 个问题和针对 RFA 的 44 个问题)对参与项目的 RFA 和风湿病医生进行了调查。此外,还为风湿病学家举行了焦点小组会议,会议由一名主持人和一名秘书主持。焦点小组会议的结果(定性分析)按照 Kuckartz 的结构化方法进行了分析:参与项目的所有 31 位区域外科医生和 25 位风湿病学家都参加了在线调查,9 位区域外科医生参加了 2 个焦点小组。在网上调查中,区域联邦医生和风湿病学家对区域联邦医生的培训、在诊所和门诊实施委托治疗的情况、区域联邦医生的作用以及对委托治疗理念的总体评价均以 "好 "和 "非常好 "为主。在焦点小组讨论中,与会者提到了在接受和实施委托概念方面可能存在的许多限制:结论:风湿免疫科医生和风湿免疫科医师双方都积极评价并高度认可向风湿免疫科医师下放医疗任务的理念。在个体诊所和医院门诊部之间进行比较时,在实施委托概念的意愿和后勤可能性方面仍存在明显的差异。
{"title":"[Positive experiences of specialist assistants and physicians with respect to the delegation research project StaerkeR : Evaluation of the training and experiences within the framework of this project].","authors":"Anna Mai, Sandra Abrantes Diaz, Michelle Stein, Robin Denz, Renate Klaaßen-Mielke, Nina Timmesfeld, Dietmar Krause, Jürgen Braun","doi":"10.1007/s00393-022-01298-y","DOIUrl":"10.1007/s00393-022-01298-y","url":null,"abstract":"<p><strong>Introduction: </strong>The delegation of medical services to rheumatology assistants (RFA) has proven to be safe and effective in the evaluation of the research project \"StaerkeR\". Afterwards, the experiences of the participating RFAs and rheumatologists with delegation were surveyed and discussed within the framework of an opinion research project.</p><p><strong>Methods: </strong>At the end of the project, the participating RFAs and rheumatologists were surveyed via an online questionnaire (quantitative analysis) (21 questions for physicians and 44 questions for RFAs). In addition, focus group meetings were held for the RFAs, which were led by a moderator and a secretary. The results of the focus group sessions (qualitative analyses) were analyzed according to the structured method of Kuckartz.</p><p><strong>Results: </strong>All 31 RFAs and 25 rheumatologists involved in the project participated in the online surveys and 9 RFAs took part in the 2 focus groups. In the online surveys, both the RFAs and the rheumatologists gave predominantly good to very good ratings with respect to RFA training, the implementation of delegation in the practices and outpatient clinics, the role of the RFAs and the overall evaluation of the delegation concept. In the focus group discussions, many possible limitations regarding acceptance and implementation of the delegation concept were mentioned.</p><p><strong>Conclusion: </strong>The delegation of medical tasks to RFAs is a concept that is positively assessed and highly accepted by both sides, the rheumatologists and the RFAs. In a comparison between the individual practices and hospital outpatient departments, there is still a clear heterogeneity with respect to the willingness and logistical possibilities in the implementation of the delegation concept.</p>","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10973023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10361761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Wearables in rheumatology]. [风湿病学中的可穿戴设备]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2023-06-08 DOI: 10.1007/s00393-023-01377-8
Tingting Xiong, Martin Krusche

As a result of digitalization in medicine wearable computing devices (wearables) are becoming increasingly more important. Wearables are small portable electronic devices with which the user can record data relevant to health, such as number of steps, activity profile, electrocardiogram (ECG), heart and breathing frequency or oxygen saturation. Initial studies on the use of wearables in patients with rheumatological diseases show the opening up of new possibilities for prevention, disease monitoring and treatment. This study provides the current data situation and the implementation of wearables in the discipline of rheumatology. Additionally, future potential fields of application as well as challenges and limits of the implementation of wearables are illustrated.

随着医疗数字化的发展,可穿戴计算设备(可穿戴设备)变得越来越重要。可穿戴设备是一种小型便携式电子设备,用户可以用它记录与健康有关的数据,如步数、活动情况、心电图(ECG)、心跳和呼吸频率或血氧饱和度。关于风湿病患者使用可穿戴设备的初步研究表明,可穿戴设备为预防、监测和治疗疾病提供了新的可能性。本研究提供了风湿病学科目前的数据情况和可穿戴设备的实施情况。此外,还说明了未来潜在的应用领域以及实施可穿戴设备所面临的挑战和限制。
{"title":"[Wearables in rheumatology].","authors":"Tingting Xiong, Martin Krusche","doi":"10.1007/s00393-023-01377-8","DOIUrl":"10.1007/s00393-023-01377-8","url":null,"abstract":"<p><p>As a result of digitalization in medicine wearable computing devices (wearables) are becoming increasingly more important. Wearables are small portable electronic devices with which the user can record data relevant to health, such as number of steps, activity profile, electrocardiogram (ECG), heart and breathing frequency or oxygen saturation. Initial studies on the use of wearables in patients with rheumatological diseases show the opening up of new possibilities for prevention, disease monitoring and treatment. This study provides the current data situation and the implementation of wearables in the discipline of rheumatology. Additionally, future potential fields of application as well as challenges and limits of the implementation of wearables are illustrated.</p>","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10973074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9964587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Zeitschrift fur Rheumatologie
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