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Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns最新文献

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[Effects of the anterolateral thigh chimeric perforator flaps in repairing complex wounds of foot and ankle]. 【股前外侧嵌合体穿支皮瓣修复足踝复杂创伤的效果】。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20230627-00232
P Ji, T Cao, Z Zhang, Z Zheng, M Liang, C Y Tian, T Hao, L L Chen, D H Hu, J T Han, K Tao

Objective: To investigate the effects of anterolateral thigh chimeric perforator flap in repairing complex wounds of foot and ankle. Methods: A retrospective observational study was conducted. From May 2018 to June 2022, 23 patients who met the inclusion criteria were admitted to the First Affiliated Hospital of Air Force Medical University to repair complex wounds of foot and ankle with anterolateral thigh chimeric perforator flaps, including 15 males and 8 females, aged from 20 to 66 years. The wounds were all accompanied by bone exposure and defects, and were complicated with varying degrees of infection. All patients underwent debridement and continuous vacuum sealing drainage treatment for 1 week in stage Ⅰ, with the skin and soft tissue defect area after debridement being 10 cm×5 cm to 22 cm×7 cm. In stage Ⅱ, the anterolateral thigh chimeric perforator flap was used to cover the defective wound, of which the muscle flap was used to fill the deep invalid cavity of the ankle joint or cover bone and internal fixation exposures, and the skin flap was used to cover the superficial wound, with the area of the skin flap ranging from 11 cm×6 cm to 23 cm×8 cm, and the area of the muscle flap ranging from 4.0 cm×2.5 cm to 8.0 cm×5.0 cm. The survival of the flap was observed after operation. During follow-up, the color, texture, appearance, and complications of the flap were observed, the function of ankle joint and its range of dorsiflexion motion and plantar flexion motion were measured, and the scar hyperplasia and muscular hernia in donor area were observed. Results: Ecchymosis and epidermal necrosis occurred at the tip of the flap in 1 patient on 5 days after operation and healed after dressing change for 1 week; the other flaps of patients survived successfully. After 6 to 40 months of follow-up, the color, texture, and shape of flaps were good, but 1 patient was not satisfied with the shape of the flap because of flap swelling; the ankle joint movement was basically normal, the dorsiflexion motion was 15-30°, and the plantar flexion motion was 20-45°; the scar hyperplasia in the donor area of the flap was not obvious, and no muscular hernia occurred. Conclusions: The anterolateral thigh chimeric perforator flap can effectively fill the deep invalid cavity of ankle joint and cover the superficial wound at the same time, with minimal damage to the donor site. So it is an ideal flap for repairing the complex wounds of foot and ankle.

目的:探讨股前外侧嵌合体穿支皮瓣修复足踝复杂创面的效果。方法:采用回顾性观察研究。2018年5月至2022年6月,23名符合入选标准的患者入住空军医科大学第一附属医院,采用股前外侧嵌合体穿支皮瓣修复足踝复杂伤口,其中男性15例,女性8例,年龄在20-66岁之间。伤口均伴有骨外露和缺损,并伴有不同程度的感染。所有患者在Ⅰ期均进行清创和持续真空封闭引流治疗1周,清创后皮肤和软组织缺损面积为10cm×5cm至22cm×7cm,其中肌瓣用于填充踝关节深部无效腔或覆盖骨和内固定暴露,皮瓣用于覆盖浅表伤口,皮瓣面积为11cm×6cm~23cm×8cm,肌瓣面积为4.0cm×2.5cm~8.0cm×5.0cm。随访期间,观察皮瓣的颜色、质地、外观和并发症,测量踝关节功能及其背屈和跖屈运动范围,观察供区瘢痕增生和肌疝。结果:1例患者术后5天皮瓣尖端出现瘀斑和表皮坏死,换药1周后愈合;其余皮瓣均成功成活。随访6~40个月后,皮瓣的颜色、质地和形状均良好,但1例患者因皮瓣肿胀对皮瓣的形状不满意;踝关节运动基本正常,背屈运动15~30°,跖屈运动20~45°;皮瓣供区瘢痕增生不明显,无肌疝发生。结论:股前外侧嵌合体穿支皮瓣可有效填充踝关节深部无效腔,同时覆盖浅表创面,对供区损伤最小。是修复足踝复杂创伤的理想皮瓣。
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引用次数: 0
[Research progress on prevention and treatment of deep vein thrombosis in burn patients]. 【烧伤患者深静脉血栓形成的防治研究进展】。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20220601-00210
W B Tang, X J Li

Deep vein thrombosis (DVT) and pulmonary embolism are common and serious complications in hospitalized patients. DVT may be induced by factors including the vein wall injury, hypercoagulability, and slow blood flow during the pathophysiological changes and treatment process of burn patients, especially severe burn patients. It is of great significance to understand the occurrence of DVT in burn patients, identify the high risk group of DVT formation in burn patients with effective evaluation methods, and carry out safe and effective prevention and treatment. This article briefly reviews research progress on the monitoring, prevention, and treatment of DVT in burn patients.

深静脉血栓形成(DVT)和肺栓塞是住院患者常见且严重的并发症。DVT可能是由烧伤患者,特别是严重烧伤患者在病理生理变化和治疗过程中的静脉壁损伤、高凝状态和血流缓慢等因素引起的。了解烧伤患者DVT的发生情况,用有效的评估方法识别烧伤患者DVT形成的高危人群,进行安全有效的预防和治疗,具有重要意义。本文简要综述了烧伤患者DVT的监测、预防和治疗的研究进展。
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引用次数: 0
[Clinical effects of scalp flaps pedicled with superficial temporal artery parietal branch in repairing facial destructive burn wounds]. [以颞浅动脉顶支为蒂的头皮瓣修复面部破坏性烧伤创面的临床疗效]。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20230312-00077
C D Xia, J D Xue, P P Xing, H P Di, J J Shi, J Zhang, D Y Cao, H T Xiao, L Liu, C Ma

Objective: To explore the clinical effects of scalp flaps pedicled with superficial temporal artery parietal branch in repairing facial destructive burn wounds. Methods: A retrospective observational study was conducted. From January 2016 to December 2021, 15 patients with facial destructive burns who met the inclusion criteria were admitted to Zhengzhou First People's Hospital, including 11 males and 4 females, aged 22 to 79 years. Two patients were complicated with unilateral eyeball destructive burns, two patients were complicated with unilateral auricle defects, eight patients were complicated with lip and cheek defects, and three patients were complicated with lip, cheek, and unilateral nasal alar defects. The burn wound areas ranged from 9 cm×6 cm to 13 cm×10 cm. The scalp flaps pedicled with superficial temporal artery parietal branch, with the area of 10 cm×7 cm to 15 cm×11 cm, were designed, excised, and transferred for repairing burn wounds. The secondary wounds at the donor sites were repaired with medium-thickness scalp grafts. According to patient's needs, the hairs grew at the facial transplanted flap were removed by laser at 2 weeks after the flap was completely viable, or the expanded scalp flap was used to treat the secondary alopecia in the flap donor area of the head at 3 months after the primary wound repair. The survival of the flap/skin graft and the wound healing of the donor and recipient areas after the primary wound repair were recorded. During the follow-up, the appearance of the flap, the scar hyperplasia at the suture site, the repair effect of facial functional parts, the treatment effects of laser hair removal and secondary alopecia treatment at the flap donor site were observed; the patient's satisfaction with the overall repair effect was inquired. Results: After the primary wound repair, all the flaps transplanted to the burn wounds and the skin grafts transplanted to the secondary wounds of the flap donor sites survived well, and the wounds at the donor and recipient sites of flap healed well. The color, texture, and thickness of flap were basically the same as those of normal facial skin, and the scar at the suture site was slight during 3 to 18 months of follow-up period after the primary wound repair. In 11 patients complicated with lip defects, the oral integrity, and the opening and closing functions of mouth were restored with the mouth opening being 2.0-2.5 cm and no microstomia; all the patients could carry out basic language communication, 8 of them could take regular food, and 3 of them could take soft food. The wounds in two patients with unilateral eyeball destructive burns were repaired. In 2 patients complicated with auricle defects, the wounds were repaired, and the external auditory canals were normal. In 3 patients complicated with unilateral nasal alar defects, their noses had poor appearance with reduced nostrils. No hair growth was observed in the facial flap sites

目的:探讨以颞浅动脉顶支为蒂的头皮瓣修复面部破坏性烧伤创面的临床效果。方法:采用回顾性观察研究。2016年1月至2021年12月,郑州市第一人民医院收治了15名符合入选标准的面部破坏性烧伤患者,其中男性11名,女性4名,年龄在22-79岁之间。2例并发单侧眼球破坏性烧伤,2例并发双侧耳廓缺损,8例并发唇颊缺损,3例并发唇、颊和单侧鼻翼缺损。烧伤面积9 cm×6 cm~13 cm×10 cm,设计、切除、转移以颞浅动脉顶支为蒂的10 cm×7 cm~15 cm×11 cm头皮瓣,用于烧伤创面修复。供体部位的继发性伤口用中等厚度的头皮移植物修复。根据患者需要,在皮瓣完全成活后2周用激光去除面部移植皮瓣处生长的毛发,或在初次伤口修复后3个月用扩张头皮皮瓣治疗头部皮瓣供区继发性脱发。记录皮瓣/皮肤移植物的存活率以及初次伤口修复后供体和受体区域的伤口愈合情况。随访中观察皮瓣外观、缝合部位瘢痕增生、面部功能部位修复效果、激光脱毛及皮瓣供区继发性脱发治疗效果;询问患者对整体修复效果的满意度。结果:烧伤创面一次修复后,所有皮瓣移植及皮瓣供区二次创面植皮均成活良好,皮瓣供区及受区创面愈合良好。皮瓣的颜色、质地和厚度与正常面部皮肤基本相同,伤口初次修复后随访3至18个月,缝合处瘢痕轻微。11例唇缘缺损患者,口腔完整性及口部开闭功能恢复,口部开口2.0-2.5cm,无微小切口;所有患者都能进行基本的语言交流,其中8人能正常进食,3人能吃软性食物。对两例单侧眼球破坏性烧伤患者的创面进行了修复。2例合并耳廓缺损的患者,创面得到修复,外耳道正常。3例合并单侧鼻翼缺损的患者,其鼻部外观较差,鼻孔缩小。8例患者经激光脱毛治疗后,皮瓣部位未见毛发生长。5名患者成功地使用扩张头皮皮瓣治疗了头部皮瓣供区的继发性脱发。患者对整体修复效果均满意。结论:以颞浅动脉顶支为蒂的头皮瓣血供丰富,适用于面部破坏性烧伤创面的修复。它易于转移,可以更好地恢复受区的外观和功能,对皮瓣供区的损伤最小,值得临床推广。
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引用次数: 0
[Expert consensus on the management of deep partial-thickness burn wounds in pediatric patients (2023 version)]. 【儿科患者深部部分厚度烧伤创面处理专家共识(2023年版)】。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20230730-00026

Burns are the leading cause of accidental injuries among Chinese children. Due to the strong wound repair ability and the demand for growth and development in pediatric patients, there are many options for the treatment of deep partial-thickness burn wounds in pediatric patients, while many controversies about the strategies for treatment of this kind of wounds also exist. This article assembled the consensus reached by experts in burns and relevant fields in China and abroad on the management of thermal-induced deep partial-thickness burn wounds in pediatric patients aged 1-6 years, including definition and diagnosis, surgical treatment, non-surgical treatment, wound dressings, application of growth factors, treatment of infectious wounds, prevention and treatment of scar, to provide guiding recommendations for the diagnosis and treatment of deep partial-thickness burn wounds in pediatric patients in China.

烧伤是中国儿童意外伤害的主要原因。由于儿童患者具有较强的伤口修复能力和对生长发育的需求,治疗儿童深部部分厚度烧伤伤口有多种选择,但对这类伤口的治疗策略也存在许多争议。本文汇集了国内外烧伤及相关领域专家对1-6岁儿童热致深部偏厚烧伤创面管理的共识,包括定义与诊断、手术治疗、非手术治疗、创面敷料、生长因子的应用、感染性创面的治疗,瘢痕的预防和治疗,为我国儿科深部偏厚烧伤患者的诊断和治疗提供指导性建议。
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引用次数: 0
[Selection strategy of pedicled axial flaps for repairing high-voltage electric burn wounds in foot and ankle]. [带蒂轴状皮瓣修复脚踝高压电烧伤创面的选择策略]。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20230613-00212
H Y Zhong, Y Chen, X Y Du, Q Wang, M Wang, M L Zou, S M Yuan

Objective: To explore the selection strategy of pedicled axial flaps for repairing high-voltage electric burn wounds in foot and ankle. Methods: The retrospective observational research method was used. From January 2017 to December 2022, 16 patients with skin and soft tissue defects in foot and ankle after high-voltage electric burns were treated in General Hospital of Eastern Theater Command, including 11 cases of unilateral defect and 5 cases of bilateral defect. All patients were male, aged from 25 to 75 years. After thorough debridement, the area of the defect to be repaired with the flap was 5.0 cm×4.0 cm to 12.0 cm×8.0 cm. Before operation, the color Doppler ultrasound, computed tomography angiography, or digital subtraction angiography was used to fully evaluate the degree of vascular injury in the affected limb and to identify the distribution and traffic anastomosis of vascular network. Pedicled axial flaps with reliable blood supply were used to repair the wounds as soon as possible, and the area of flaps ranged from 3.0 cm×2.0 cm to 13.0 cm×8.0 cm. The wound in the donor area of flaps was repaired with split-thickness skin graft from head or medium-thickness skin graft from thigh. The flap repair of wounds in various areas of the ankle and foot was recorded. The postoperative survivals of the flaps and skin grafts were observed after surgery. The postoperative appearance of flaps and walking function of patients were followed up. At the last follow-up, the foot and ankle function was evaluated and rated using the American Association of Foot and Ankle Surgeons Ankle Posterior Foot Scoring System. Results: Two wounds in toe area were repaired with reverse dorsal pedis flaps, 3 wounds in medial ankle area and 2 wounds in heel area were repaired with medial plantar flaps, 2 wounds in anterior plantar area combined with toe area were repaired with reverse medial plantar flaps, 2 wounds in anterior plantar area combined with toe area and 5 wounds in anterior plantar area were repaired with reverse medial pedis flaps, 1 wound in toe area was combined with proper plantar digital artery flap, 1 dorsal pedis wound and 1 lateral malleolus wound were repaired with lateral supramalleolar perforator flaps, and 1 lateral malleolus wound and 1 dorsal pedis wound were repaired with sural neurovascular flap. One flap had venous reflux disorder after surgery and survived after treatment, while the other flaps and skin grafts survived completely after surgery. During the follow-up of 6 to 24 months after operation, the appearance of the flaps was good, and the walking function of patients was normal. At the last follow-up, the functional score of foot and ankle was 76 to 95, which was evaluated as excellent in 11 cases and good in 5 cases. Conclusions: According to the condition of high-voltage electric burn in foot and ankle, early and thorough debridement, preoperative imaging examination to evaluate blood vessels of

目的:探讨带蒂轴状皮瓣修复足踝高压电烧伤创面的选择策略。方法:采用回顾性观察研究方法。2017年1月至2022年12月,在东部战区司令部总医院治疗16例高压电烧伤足踝皮肤及软组织缺损患者,其中单侧缺损11例,双侧缺损5例。所有患者均为男性,年龄在25至75岁之间。彻底清创后,用皮瓣修复的缺损面积为5.0cm×4.0cm至12.0cm×8.0cm。术前,使用彩色多普勒超声、计算机断层造影或数字减影血管造影来全面评估患肢的血管损伤程度,并确定血管网的分布和交通吻合。皮瓣面积3.0cm×2.0cm~13.0cm×8.0cm,皮瓣供区创面采用头部中厚皮片或大腿中厚皮修复。记录了踝关节和足部不同部位伤口的皮瓣修复情况。术后观察皮瓣和皮片的成活率。随访患者术后皮瓣外观及行走功能。在最后一次随访中,使用美国足踝外科医生协会踝关节后足评分系统对足踝功能进行评估和评分。结果:足背逆行皮瓣修复足趾区2处,足踝内侧区3处,足跟区2处,足底前区合并足趾区2处、足底前区5处用足内侧逆行皮瓣修复,足趾区1处用足趾固有动脉皮瓣修复,足背侧1处、外踝侧1处用踝上外侧穿支皮瓣修复,用腓肠神经血管皮瓣修复1例外踝伤和1例足背伤。其中一个皮瓣在手术后出现静脉回流障碍,并在治疗后存活,而另一个皮瓣和皮肤移植物在手术后完全存活。术后随访6~24个月,皮瓣外观良好,患者行走功能正常。在最后一次随访中,足部和脚踝的功能评分为76至95,11例评估为优秀,5例评估为良好。结论:根据足踝高压电烧伤的情况,早期彻底清创,术前影像学检查评估患肢血管,选择血液供应可靠的带蒂轴状皮瓣,是足踝高压烧伤创面修复及相关功能重建的良好方法。
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引用次数: 0
[Effects of miniature free groin perforator flaps in repairing small wounds on hands]. [微型游离腹股沟穿支皮瓣修复手部小伤口的效果]。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20230701-00244
F Liu, W Zhang, W G Xie, L Chen, W D Zhang, J X Zhou, Z Li

Objective: To investigate the effects of miniature free groin perforator flaps in repairing small wounds on hands. Methods: The retrospective observational study was conducted. Fifteen patients with 16 small wounds on hands were admitted to Tongren Hospital of Wuhan University & Wuhan Third Hospital from July 2020 to October 2022, including 12 males and 3 females, aged 19 to 56 years. The size of skin and soft tissue defect was 2.0 cm×1.5 cm to 6.0 cm×3.0 cm after debridement. According to size and shape of the wounds, 13 single-lobe perforator flaps and 2 bilobed perforator flaps were designed in the groin region, with the flap size of 4.5 cm×2.5 cm to 7.5 cm×3.5 cm. According to the condition of the recipient area, the arteries and veins at the pedicle of the flap were anastomosed to the arteries and veins of the recipient area respectively. The wounds in the donor area of the flap was closed by layered and tension-reducing suture. The thickness of the flap was measured during operation. The survival of the flap was observed, and the complications in the donor and recipient areas were recorded after operation. The appearance and texture of the flap were observed during follow-up. At the last follow-up, the sensory recovery of the affected hand was evaluated, the function of the affected hand was evaluated according to the trial standard of the upper limb partial function evaluation of the Hand Surgery Society of the Chinese Medical Association, the scar in the donor and recipient areas were observed, and the satisfaction of patients for the curative effects was inquired. Results: The thickness of the flap was ranged from 0.3 to 1.0 cm, with an average thickness of 0.6 cm. After operation, 11 single-lobe flaps and 2 bilobed flaps survived well; in the left 2 single-lobe flaps, one flap had venous crisis but returned to normal after removing stitches to reduce tension and bloodletting of flaps, while the other one flap had a little necrosis on tip but healed after dressing change. No complications occurred in donor and recipient areas. During follow-up of 8 to 35 months after operation, the flaps had good elasticity and soft texture; 8 flaps were slightly bloated and were trimmed 3 to 8 months after operation, while the appearances of the other flaps were good. At the last follow-up, all flaps recovered protective feeling; the function of the affected hand was evaluated as excellent in 10 cases, good in 4 cases, and fair in 1 case; only linear scar remained in the donor and recipient areas; the patients were satisfied with the appearance and function recovery of the affected hand. Conclusions: The miniature free groin perforator flaps in repairing small wounds on hands have the advantages of high survival rate of flaps, hidden flap donor area, little damage, few complications, good repair effect, etc., showing clinical application value. It is recommended for repairing non-functional wounds on hands.

目的:探讨微型游离腹股沟穿支皮瓣修复手部小伤口的效果。方法:采用回顾性观察研究。2020年7月至2022年10月,武汉大学同仁医院和武汉市第三医院收治了15名手部有16处小伤口的患者,其中包括12名男性和3名女性,年龄在19至56岁之间。清创术后皮肤及软组织缺损大小为2.0cm×1.5cm~6.0cm×3.0cm。根据伤口大小和形状,在腹股沟区设计了13个单叶穿支皮瓣和2个双叶穿支瓣,皮瓣大小为4.5cm×2.5cm至7.5cm×3.5cm。根据受区情况,将皮瓣蒂动脉和静脉分别与受区动脉和静脉吻合。皮瓣供区创面采用分层减压缝合。术中测量皮瓣厚度。观察皮瓣的存活情况,并记录术后供区和受体区的并发症。在随访中观察皮瓣的外观和质地。在最后一次随访中,评估患手的感觉恢复情况,按照中华医学会手外科学会上肢部分功能评估试验标准对患手的功能进行评估,观察供受区瘢痕,询问患者对疗效的满意度。结果:皮瓣厚度0.3~1.0cm,平均厚度0.6cm,术后11个单叶皮瓣和2个双叶皮瓣成活良好;左侧2个单叶皮瓣中,一个皮瓣出现静脉危象,但拆线后恢复正常,以减少皮瓣的张力和放血,另一个皮瓣尖端有点坏死,但换药后愈合。供体和受体区域均未出现并发症。术后随访8~35个月,皮瓣弹性好,质地柔软;术后3~8个月,有8个皮瓣出现轻微肿胀,其余皮瓣外观良好。最后一次随访时,所有皮瓣均恢复了保护性感觉;患手功能优10例,良4例,尚可1例;供体和受体区域仅保留线性瘢痕;患者对患手的外观和功能恢复满意。结论:微型游离腹股沟穿支皮瓣修复手部小伤口具有皮瓣成活率高、皮瓣供区隐蔽、损伤小、并发症少、修复效果好等优点,具有临床应用价值。建议用于修复手上的非功能性伤口。
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引用次数: 0
[Summary of the 14th Asia Pacific Burn Congress, the 18th Chinese Symposium on Burn Medicine, and the 2023 Huaxia Burn Forum]. 【第十四届亚太烧伤大会、第十八届中国烧伤医学研讨会、2023华夏烧伤论坛综述】。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20231011-00109
G J Mu, Y Mo, Z Q Yuan, G X Luo, G P Liang

The 14th Asia Pacific Burn Congress, the 18th Chinese Symposium on Burn Medicine, and the 2023 Huaxia Burn Forum was held successfully in Chongqing from September 13th to 16th, 2023. More than 1 000 participants from more than 10 countries and regions attended the congress, including over 100 overseas experts. The theme of the congress was homage, heritage, and innovation, and three-day academic exchange was held in the form of academician forum, keynote forum, and seven thematic sub-forums focused on the hot spots and difficulties in the fields of burns, trauma, wound repair, and related fields. The congress was compact, comprehensive, in-depth, and fruitful, with warm atmosphere at the meeting site.

第十四届亚太烧伤大会、第十八届中国烧伤医学研讨会、2023华夏烧伤论坛于2023年9月13日至16日在重庆成功举行。来自10多个国家和地区的1000多人参加了大会,其中包括100多名海外专家。大会以致敬、传承、创新为主题,以院士论坛、主题论坛、七个专题分论坛等形式,围绕烧伤、创伤、创伤修复及相关领域的热点和难点,开展了为期三天的学术交流。大会紧凑、全面、深入、富有成果,会议现场气氛热烈。
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引用次数: 0
[Research advances on application of pancreatic stone protein in the early diagnosis of sepsis]. 【胰腺结石蛋白在败血症早期诊断中的应用研究进展】。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20221120-00498
T He, W Liu, Z A Shen

Sepsis is a severe life-threatening syndrome characterized by an abnormal host response to infection that can rapidly evolve into septic shock and multiple organ failure. Treatment of sepsis depends on early identification and diagnosis as well as adequate and timely anti-infection and multi-organ functional support. In recent years, pancreatic stone protein has been widely studied as a new biomarker for sepsis. Existing evidence shows that compared with the commonly used inflammatory markers in clinical practice, pancreatic stone protein has higher sensitivity and specificity in the diagnosis of sepsis. It enables the early diagnosis of sepsis and assessment of the severity of septic patients to a certain extent. This article reviews the characteristics, biological functions, diagnostic features, and clinical application of pancreatic stone protein.

败血症是一种严重的危及生命的综合征,其特征是宿主对感染的异常反应,可迅速演变为感染性休克和多器官衰竭。败血症的治疗取决于早期识别和诊断,以及充分及时的抗感染和多器官功能支持。近年来,胰腺结石蛋白作为一种新的败血症生物标志物被广泛研究。现有证据表明,与临床常用的炎症标志物相比,胰腺结石蛋白对败血症的诊断具有更高的敏感性和特异性。它能够在一定程度上早期诊断败血症并评估败血症患者的严重程度。本文就胰结石蛋白的特点、生物学功能、诊断特点及临床应用作一综述。
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引用次数: 0
[Research advances on mental disorders in patients with extensive burns]. [大面积烧伤患者精神障碍的研究进展]。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20221116-00490
G X Gu, M Z Ran, M M Li

Extensive burns can cause nonnegligible acute and chronic damage to central nervous system of patients. The damage of central nervous system may have a profound impact on patients, including neurobehavioral changes such as post-traumatic stress disorder, depression, anxiety, and sleep disorder. These changes may persist after injury, greatly affecting patients' integration into society and return to work. This paper systematically reviewed the clinical manifestations, pathogenesis, and current intervention methods of mental disorders in patients with extensive burns, aiming to provide a basis for further understanding, prevention, and treatment of patients with mental disorders after burns.

大面积烧伤可对患者的中枢神经系统造成不可忽视的急性和慢性损伤。中枢神经系统的损伤可能对患者产生深远影响,包括神经行为变化,如创伤后应激障碍、抑郁、焦虑和睡眠障碍。这些变化可能在受伤后持续存在,极大地影响患者融入社会和重返工作岗位。本文系统综述了大面积烧伤患者精神障碍的临床表现、发病机制和目前的干预方法,旨在为进一步了解、预防和治疗烧伤后精神障碍患者提供依据。
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引用次数: 0
[Visual analysis of the current research status and hotspots of electric burns at home and abroad]. 【国内外电烧伤研究现状及热点可视化分析】。
Q3 Medicine Pub Date : 2023-10-20 DOI: 10.3760/cma.j.cn501225-20230511-00167
H X Chen, Y W Huang, W J Liu, B Liu, G B Chen, D D Zhang, P Y Chen, W Lai

Objective: To analyze the literature on electric burns published at home and abroad, and to explore the research hotspots and frontiers of electric burns. Methods: The bibliometric method was used. The Chinese and English literature related to electric burns published in China National Knowledge Infrastructure, Wanfang database, VIP database and the core collection of Web of Science database from January 1, 2013 to December 31, 2022 were searched respectively, and the CiteSpace 6.2.R2 software was used for analysis. The number of papers, authors, countries, and institutions of Chinese and English literature were counted respectively, and the co-occurrence analysis of keywords and mutation analysis and cluster analysis on the basis of the co-occurrence analysis were conducted, besides, the clustering time line figure was obtained after the keywords were sorted by time to explore the current research status and the evolution process of hotspots in the field of electric burns. Results: A total of 398 English papers were retrieved from the core collection of Web of Science database, and a total of 523 Chinese papers were retrieved from China National Knowledge Infrastructure, Wanfang database, and VIP database after duplicate check. From 2013 to 2022, the number of English literature published in the field of electric burns showed a steadily upward trend, and the number of published Chinese literature showed a downward trend and tended to be stable. In Chinese literature, a total of 302 authors as the first author published papers related to electric burns, with 17 core authors published ≥3 papers; in English literature, a total of 320 authors as the first author published papers related to electric burns. Researches on electric burns were carried out in 65 countries, with United States having the most cooperation with other countries and the largest number of papers published. A total of 512 institutions at home and abroad published papers related to electric burns, and the institutions with the largest number of Chinese and English papers were Shanghai Electric Power Hospital in China (n=14) and Hallym University in Korea (n=11), respectively. A total of 1 176 Chinese keywords and 1 068 English keywords were included for co-occurrence analysis after excluding keywords related to the searching words. The top three keywords in frequency in Chinese literature were surgical flap, wound repair, and nursing, and the top three keywords in frequency in English literature were management, epidemiology, and children. Ten clusters were obtained by keyword analysis in Chinese literature, and the largest cluster was wound healing, followed by clinical effects and surgical flaps. Seven clusters were obtained by keyword analysis in English literature, and the largest cluster was reconstructive surgical procedures, followed by chronic pain and shock. The persistent clusters in Chinese literature were wound healing and clini

目的:分析国内外电烧伤文献,探索电烧伤的研究热点和前沿。方法:采用文献计量法。分别检索2013年1月1日至2022年12月31日在中国国家知识基础设施、万方数据库、VIP数据库和Web of Science数据库核心集上发表的与电烧伤相关的中英文文献,并使用CiteSpace 6.2.R2软件进行分析。分别统计了中英文文献的论文数量、作者、国家和机构,并在共现分析的基础上进行了关键词的共现分析、突变分析和聚类分析,将关键词按时间排序后得到聚类时间线图,以探讨电烧伤领域的研究现状和热点的演变过程。结果:从Web of Science数据库核心库中检索到398篇英文论文,从中国国家知识基础设施、万方数据库和VIP数据库中检索到523篇中文论文。2013-2022年,电烧伤领域发表的英文文献数量呈稳步上升趋势,发表的中文文献数量呈下降趋势并趋于稳定。在中国文献中,共有302位作者作为第一作者发表了与电烧伤相关的论文,其中17位核心作者发表了≥3篇论文;在英国文献中,共有320位作者作为第一作者发表了与电烧伤有关的论文。对电烧伤的研究在65个国家进行,其中美国与其他国家的合作最多,发表的论文最多。国内外共有512家机构发表了与电烧伤相关的论文,中英文论文数量最多的机构分别是中国上海电力医院(n=14)和韩国韩大(n=11)。在排除与搜索词相关的关键词后,共包括1176个中文关键词和1068个英文关键词进行共现分析。中文文献中频率最高的三个关键词是外科皮瓣、伤口修复和护理,英文文献中频率最低的三个关键字是管理、流行病学和儿童。通过中文文献中的关键词分析获得了10个聚类,最大的聚类是伤口愈合,其次是临床效果和手术皮瓣。通过英语文献中的关键词分析获得了七个聚类,最大的聚类是重建外科手术,其次是慢性疼痛和休克。中国文献中持续存在的集群是伤口愈合和临床结果等,近两年突出的节点是手术时机、肢体电烧伤和增生性瘢痕;英文文献中的持续聚类为重建手术和慢性疼痛等,近两年的突出节点为预测因素和烧伤处理等。在中文文献中,突变持续时间最长的关键词(2017-2021)为手腕电烧伤,突变强度最高的关键词为皮瓣修复;在英语文献中,突变持续时间最长的关键词(2019-2022)是电压,突变强度最高的关键词是预防。结论:国内外电烧伤的研究方向和热点存在异同。外科皮瓣修复是国内外共同的研究热点。目前,国内研究主要集中在伤口愈合、手腕电烧伤等方面,国际研究主要集中于治疗管理、流行病学、重建等方面。
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引用次数: 0
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Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns
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