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Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns最新文献

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[Curative effects of ultrathin anterolateral femoral flap in one-stage split-finger repair of palmar combined with multiple finger wounds]. 【超薄股前外侧皮瓣一期修复掌侧裂指合并多指伤的疗效观察】。
Q3 Medicine Pub Date : 2023-09-20 DOI: 10.3760/cma.j.cn501225-20221129-00514
H P Di, P P Xing, J J Zheng, C Ma, W X Huang, L Liu, J D Xue, H N Guo, G Y Yang, C D Xia, C Zhou
<p><p><b>Objective:</b> To explore the curative effects of ultrathin anterolateral femoral flap in one-stage split-finger repair of palmar combined with multiple finger wounds. <b>Methods:</b> A retrospective observational study was conducted. From October 2016 to June 2018, 20 patients with wounds on palms and multiple fingers who met the inclusion criteria were admitted to Zhengzhou First People's Hospital, including 15 males and 5 females, aged 18 to 77 years. After debridement, the wound area was 8 cm×4 cm-17 cm×12 cm. The wound was repaired by ultrathin anterolateral femoral flap with area of 9 cm×5 cm to 19 cm×13 cm. According to the wound condition of finger, the finger division was performed in one stage, and the length-to-width ratio of the split-finger flap was 2.0:1.0-2.5:1.0. During the surgery, the descending branches of lateral circumflex femoral artery and accompanying vein of flap were anastomosed end-to-end to the radial artery and vein in the recipient area, respectively, and the anterolateral femoral cutaneous nerve of flap was bridged with the superficial branch of radial nerve in the recipient area. The wounds in the donor area of flap in 14 patients were sutured directly, the wounds in the donor area of flap in 3 patients were repaired by relay superficial iliac circumflex artery perforator flap, and the wounds in the donor area of flap in 3 patients were covered by free trunk medium-thick skin graft. The survival of flap, occurrence of vascular crisis and other complications, and healing of wounds in the donor area of flap were recorded. The appearance of flap, scar hyperplasia in the donor and recipient areas and the patients' satisfaction with the shape and function of the donor and recipient areas were followed up. In 1 year after surgery, the two-point discrimination distance of the flap was measured, and the recovery of hand function was evaluated by the trial standard for the evaluation of the functions of the upper limbs of the Hand Surgery Society of the Chinese Medical Association. <b>Results:</b> The flaps of 17 patients survived without vascular crisis or other complications after surgery. The flap of 1 patient had poor blood circulation and partial necrosis, and the wound was healed 14 days after dressing change and grafting of split-thickness skin graft from head. Two patients had mild cyanosis at the margin of flap after surgery, which disappeared spontaneously 5 days later. Incisions at donor site, relay flaps, and skin grafts of all patients survived well. After surgery, the color and texture of flap were basically the same as that of the normal skin of hand, and linear scars were observed in the donor and recipient areas. The patients were satisfied with the recovery of appearance and function of donor and recipient areas. After 1 year of follow-up, the patients' hand sensory function recovered well, the two-point discrimination distance of flap was 4-6 mm, and the recovery of hand function was evaluated as
目的:探讨超薄股前外侧皮瓣一期修复掌侧裂指合并多指损伤的疗效。方法:采用回顾性观察研究。2016年10月至2018年6月,郑州市第一人民医院收治了20名符合入选标准的手掌和多指伤口患者,其中男性15名,女性5名,年龄18至77岁。清创后创面面积为8cm×4cm×17cm×12cm,采用超薄股前外侧皮瓣修复,面积为9cm×5cm~19cm×13cm,根据手指的创面情况,分一期进行手指分割,分割指皮瓣的长宽比为2.0:1.0-2.5:1.0。术中,皮瓣旋股外侧动脉和伴行静脉的下行支分别与受体区的桡动脉和桡静脉端对端吻合,皮瓣股前外侧皮神经与受体区桡神经浅支桥接。14例直接缝合皮瓣供区创面,3例采用旋髂浅动脉穿支皮瓣修复,3例皮瓣供区采用游离干-中厚皮片覆盖。记录皮瓣的成活率、血管危象和其他并发症的发生以及皮瓣供区伤口的愈合情况。随访皮瓣外观、供受区瘢痕增生情况及患者对供受区形状和功能的满意度。术后1年测量皮瓣两点判别距离,采用中华医学会手外科学会上肢功能评定试验标准评定手功能恢复情况。结果:17例患者术后皮瓣成活,无血管危象及其他并发症。1例皮瓣血运不畅,局部坏死,换药后14天创面愈合。两名患者术后皮瓣边缘轻度发绀,5天后自发消失。所有患者的供区切口、中继皮瓣和皮肤移植均存活良好。术后皮瓣的颜色和质地与手部正常皮肤基本一致,供、受区均可见线状瘢痕。患者对供体和受体区域的外观和功能恢复感到满意。经过1年的随访,患者的手部感觉功能恢复良好,皮瓣两点辨别距离为4-6mm,手部功能恢复评价为优18例,良2例。结论:超薄股前外侧皮瓣修复一期裂指手掌合并多指创面,可显著减少手术次数,改善手部功能和美观,值得临床推广。
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引用次数: 0
[Clinical effects of expanded frontal flap and flip scar flap in repairing partial nasal defect]. [额皮瓣和瘢痕翻转皮瓣修复鼻部分缺损的临床疗效]。
Q3 Medicine Pub Date : 2023-09-20 DOI: 10.3760/cma.j.cn501225-20230517-00173
F F Chu, Y K Tang, J K Ding, Y Zhang, W Liu, X J Ma

Objective: To investigate the clinical effects of expanded frontal flap and flip scar flap in repairing partial nasal defect. Methods: A retrospective observational study was conducted. From January 2012 to January 2022, 26 patients with partial nasal defects who met the inclusion criteria were admitted to the First Affiliated Hospital of Air Force Medical University, including 19 males and 7 females, aged 5 to 61 years. The surgery was performed in 4 stages. In the first stage, a rectangular skin and soft tissue expander (hereinafter referred to as expander) with suitable rated capacity was planted in frontal region and expanded by injecting water regularly. In the second stage, flip scar flap was grafted to reconstruct nasal inner lining, whose area was about 10% larger than the area of defect. The expanded frontal flap with pedicle was transferred to repair the nasal defect, whose pedicle was supraorbital vessel or supratrochlear vessel on the contralateral side of the defect, and the area of expanded flap was 20% larger than the nasal defect area after resection and flipping of scar flap. The donor site of expanded flap was sutured directly. After 3 weeks of flap transferring, the flap was delayed in the third stage. After 1 week of delaying operation, the pedicle of flap was cut off in the fourth stage. The number, rated capacity, injection volume, and expansion time of embedded expanders were recorded. The occurrences of complications including infection, hematoma, ulceration of expanded flap after the first stage operation, and blood supply disorder or necrosis of flap after operation in the second and fourth stages were observed. All the patients were followed up for 1 year at least, and the color of flap, scar of frontal donor site, symmetry of bilateral eyebrows, and the nasal appearance and ventilated function of external nasal tract were observed. Results: A total of 26 expanders were embedded in 26 patients. The rated capacity of expanders ranged from 100 to 300 mL. The injection volume was 1.0 to 1.5 times of the rated capacity of expanders. The expansion time ranged from 2.5 to 4.0 months, with an average time of 3 months. There were no complications occurred after each operation. The follow-up showed that the color of flap was similar to the normal nasal skin, the scar of frontal region was not obvious, the bilateral eyebrows were basically symmetrical, the nose had excellent appearance, ventilation function of external nasal tract was not affected, while some of the patients had downward rotation or unapparent tip-defining point of nose. Conclusions: Using the flip scar flap to reconstruct the nasal inner lining and pre-expanded frontal flap to reconstruct the nasal skin, without free cartilage transplantation to repair the partial nasal defects can achieve satisfied nasal appearance post operation, without abnormal external nasal ventilation function.

目的:探讨额皮瓣和翻瘢痕皮瓣修复鼻部分缺损的临床效果。方法:采用回顾性观察研究。2012年1月至2022年1月,空军医科大学第一附属医院共收治26例符合纳入标准的鼻部分缺损患者,其中男19例,女7例,年龄5~61岁。手术分4个阶段进行。在第一阶段,将具有适当额定容量的矩形皮肤和软组织扩张器(以下简称扩张器)种植在额叶区域,并通过定期注水进行扩张。在第二阶段,采用翻转瘢痕瓣移植重建鼻腔内衬,其面积比缺损面积大10%左右。转移带蒂额扩张皮瓣修复鼻缺损,其蒂为缺损对侧的眶上血管或滑车上血管,瘢痕瓣切除翻转后,扩张皮瓣面积比鼻缺损面积大20%。扩张皮瓣供区直接缝合。皮瓣移植3周后,第三期皮瓣出现延迟。延迟手术1周后,在第四阶段切除皮瓣蒂。记录嵌入式膨胀机的数量、额定容量、注入量和膨胀时间。观察第一期术后扩张皮瓣发生感染、血肿、溃疡等并发症,第二、四期术后皮瓣出现血供紊乱或坏死等并发症。随访1年以上,观察皮瓣颜色、额供区瘢痕、双侧眉毛对称性、鼻腔外观及外鼻道通气功能。结果:26例患者共植入26个扩张器。扩张器的额定容量在100-300mL之间。注射量是扩张器额定容量的1.0-1.5倍。扩张时间为2.5至4.0个月,平均3个月。每次手术后均无并发症发生。随访发现皮瓣颜色与正常鼻部皮肤相似,额部瘢痕不明显,双侧眉毛基本对称,鼻部外形美观,外鼻道通气功能不受影响,部分患者鼻尖分界点向下旋转或不明显。结论:采用翻转瘢痕瓣重建鼻腔内衬,额前扩张皮瓣重建鼻腔皮肤,无需游离软骨移植修复部分鼻腔缺损,术后鼻腔外观满意,无异常外鼻通气功能。
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引用次数: 0
[Influence of family with sequence similarity 134, member B-mediated reticulophagy on lipopolysaccharide-induced apoptosis of mouse dendritic cells]. [具有序列相似性的家族134,成员B介导的网状食道对脂多糖诱导的小鼠树突状细胞凋亡的影响]。
Q3 Medicine Pub Date : 2023-09-20 DOI: 10.3760/cma.j.cn501225-20230227-00063
Y Duan, R Q Yao, L Y Zheng, N Dong, Y Wu, Y M Yao, X G Dai
<p><p><b>Objective:</b> To investigate the influence of family with sequence similarity 134, member B (FAM134B)-mediated reticulophagy on lipopolysaccharide (LPS)-induced apoptosis of mouse dendritic cells (DCs), so as to provide a basis for improving the immune suppression of sepsis caused by wound infection and other factors. <b>Methods:</b> The experimental research methods were used. The DC line DC2.4 of the 3<sup>rd</sup> to 10<sup>th</sup> passage in the logarithmic growth stage was collected for experiments. DCs were divided into LPS stimulation 0 h (no stimulation) group, LPS stimulation 6 h group, LPS stimulation 12 h group, LPS stimulation 24 h group, and LPS stimulation 72 h group, which were cultured with 1 μg/mL LPS (the same concentration below) for the corresponding time. The protein expressions of FAM134B, microtubule-associated protein 1 light chain 3B (LC3B), and transporter protein SEC61B were determined by Western blotting, and the ratio of LC3B-Ⅱ/LC3B-Ⅰ was calculated (<i>n</i>=3). DCs were divided into phosphate buffer solution (PBS) group and LPS group for corresponding treatment. After 24 hours of culture, the expression of FAM134B and its co-localization with lysosomal probes and LC3B were detected using immunofluorescence method, while the number of autolysosomes in cells were observed through transmission electron microscope. DCs were divided into the FAM134B-knockdown group that were transfected with lentivirus containing small interfering RNA (siRNA) sequence of <i>FAM134B</i> gene and the empty vector group with empty lentivirus transfected. At post transfection hour 72, the fluorescence expression of cells was observed under the inverted fluorescence phase contrast microscope, meanwhile, the normally cultured DCs were set as blank control group, and the same observation was performed at the corresponding time point. DCs were divided into PBS alone group and LPS alone group, DCs successfully transfected with lentivirus containing siRNA sequence of <i>FAM134B</i> gene were divided into FAM134B-knockdown+PBS group and FAM134B-knockdown+LPS group, and DCs successfully transfected with empty lentivirus were divided into empty vector+PBS group and empty vector+LPS group. These cells were stimulated correspondingly and cultured for 24 hours. The protein expression of FAM134B was detected using Western blotting (<i>n</i>=3); the apoptotic rate of cells was determined by flow cytometry (<i>n</i>=3); the situation of apoptosis was observed by Hoechst staining, and the apoptotic rate was calculated (<i>n</i>=5); the protein expressions of cleaved cysteine aspartic acid specific protease-3 (caspase-3), B cell lymphoma 2 (Bcl-2), and Bcl-2-associated X protein (Bax) were detected using Western blotting, and the ratio of Bax/Bcl-2 was calculated (<i>n</i>=5). Data were statistically analyzed with one-way analysis of variance (ANOVA), least significant difference test, and ANOVA for factorial design. <b>Results:</b> Compared with
目的:探讨序列相似性家族134,成员B(FAM134B)介导的网状食管对脂多糖(LPS)诱导的小鼠树突状细胞(DC)凋亡的影响,为提高伤口感染等因素引起的败血症的免疫抑制作用提供依据。方法:采用实验研究方法。收集对数生长期第3代至第10代的DC系DC2.4进行实验。将DC分为LPS刺激0 h(无刺激)组、LPS刺激6 h组、LPS激励12 h组、脂多糖激励24 h组和LPS激励72 h组,用1μg/mL LPS(以下相同浓度)培养相应时间。用蛋白质印迹法测定FAM134B、微管相关蛋白1轻链3B(LC3B)和转运蛋白SEC61B的蛋白表达,并计算LC3B-Ⅱ/LC3B-Ⅰ的比值(n=3)。将DC分为磷酸盐缓冲液(PBS)组和LPS组进行相应的处理。培养24小时后,用免疫荧光法检测FAM134B的表达及其与溶酶体探针和LC3B的共定位,同时用透射电镜观察细胞中自溶体的数量。将DC分为用含有FAM134B基因的小干扰RNA(siRNA)序列的慢病毒转染的FAM134B敲除组和用转染的空慢病毒的空载体组。转染后72小时,在倒置荧光相差显微镜下观察细胞的荧光表达,同时将正常培养的DC设为空白对照组,并在相应时间点进行相同的观察。将DC分为单独PBS组和单独LPS组,用含有FAM134B基因siRNA序列的慢病毒成功转染的DC分为FAM134B+PBS敲除组和FAM134B+LPS敲除组,用空慢病毒成功转导的DC分为由空载体+PBS组和空载体+LPS组。相应地刺激这些细胞并培养24小时。使用蛋白质印迹法检测FAM134B的蛋白质表达(n=3);流式细胞仪检测细胞凋亡率(n=3);Hoechst染色观察细胞凋亡情况,计算细胞凋亡率(n=5);用蛋白质印迹法检测裂解半胱氨酸天冬氨酸特异性蛋白酶-3(胱天蛋白酶-3)、B细胞淋巴瘤2(Bcl-2)和Bcl-2相关X蛋白(Bax)的蛋白表达,并计算Bax/Bcl-2的比值(n=5)。采用单因素方差分析(ANOVA)、最小显著性差异检验和因子设计的ANOVA对数据进行统计分析。结果:与LPS刺激0 h组相比,LPS刺激12h组和LPS刺激24h组细胞FAM134B的蛋白表达均显著增加(PPPP值均为P值均为PPPPC)。结论:在LPS刺激下,FAM134B介导的小鼠DC网织食道激活增强,并在24小时内达到峰值,激活的网织食道对细胞凋亡具有显著的抑制作用。
{"title":"[Influence of family with sequence similarity 134, member B-mediated reticulophagy on lipopolysaccharide-induced apoptosis of mouse dendritic cells].","authors":"Y Duan, R Q Yao, L Y Zheng, N Dong, Y Wu, Y M Yao, X G Dai","doi":"10.3760/cma.j.cn501225-20230227-00063","DOIUrl":"10.3760/cma.j.cn501225-20230227-00063","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the influence of family with sequence similarity 134, member B (FAM134B)-mediated reticulophagy on lipopolysaccharide (LPS)-induced apoptosis of mouse dendritic cells (DCs), so as to provide a basis for improving the immune suppression of sepsis caused by wound infection and other factors. &lt;b&gt;Methods:&lt;/b&gt; The experimental research methods were used. The DC line DC2.4 of the 3&lt;sup&gt;rd&lt;/sup&gt; to 10&lt;sup&gt;th&lt;/sup&gt; passage in the logarithmic growth stage was collected for experiments. DCs were divided into LPS stimulation 0 h (no stimulation) group, LPS stimulation 6 h group, LPS stimulation 12 h group, LPS stimulation 24 h group, and LPS stimulation 72 h group, which were cultured with 1 μg/mL LPS (the same concentration below) for the corresponding time. The protein expressions of FAM134B, microtubule-associated protein 1 light chain 3B (LC3B), and transporter protein SEC61B were determined by Western blotting, and the ratio of LC3B-Ⅱ/LC3B-Ⅰ was calculated (&lt;i&gt;n&lt;/i&gt;=3). DCs were divided into phosphate buffer solution (PBS) group and LPS group for corresponding treatment. After 24 hours of culture, the expression of FAM134B and its co-localization with lysosomal probes and LC3B were detected using immunofluorescence method, while the number of autolysosomes in cells were observed through transmission electron microscope. DCs were divided into the FAM134B-knockdown group that were transfected with lentivirus containing small interfering RNA (siRNA) sequence of &lt;i&gt;FAM134B&lt;/i&gt; gene and the empty vector group with empty lentivirus transfected. At post transfection hour 72, the fluorescence expression of cells was observed under the inverted fluorescence phase contrast microscope, meanwhile, the normally cultured DCs were set as blank control group, and the same observation was performed at the corresponding time point. DCs were divided into PBS alone group and LPS alone group, DCs successfully transfected with lentivirus containing siRNA sequence of &lt;i&gt;FAM134B&lt;/i&gt; gene were divided into FAM134B-knockdown+PBS group and FAM134B-knockdown+LPS group, and DCs successfully transfected with empty lentivirus were divided into empty vector+PBS group and empty vector+LPS group. These cells were stimulated correspondingly and cultured for 24 hours. The protein expression of FAM134B was detected using Western blotting (&lt;i&gt;n&lt;/i&gt;=3); the apoptotic rate of cells was determined by flow cytometry (&lt;i&gt;n&lt;/i&gt;=3); the situation of apoptosis was observed by Hoechst staining, and the apoptotic rate was calculated (&lt;i&gt;n&lt;/i&gt;=5); the protein expressions of cleaved cysteine aspartic acid specific protease-3 (caspase-3), B cell lymphoma 2 (Bcl-2), and Bcl-2-associated X protein (Bax) were detected using Western blotting, and the ratio of Bax/Bcl-2 was calculated (&lt;i&gt;n&lt;/i&gt;=5). Data were statistically analyzed with one-way analysis of variance (ANOVA), least significant difference test, and ANOVA for factorial design. &lt;b&gt;Results:&lt;/b&gt; Compared with ","PeriodicalId":24004,"journal":{"name":"Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns","volume":"39 9","pages":"857-866"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11630182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41111946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Best evidence summary of prevention strategies for pressure injury in adult hospitalized burn patients]. [成人住院烧伤患者压力损伤预防策略的最佳证据总结]。
Q3 Medicine Pub Date : 2023-09-20 DOI: 10.3760/cma.j.cn501225-20230328-00101
L Q Han, M Y Shen, X Y Tang, P X Wan, L D Lao, T He

Objective: To summarize the best evidence of prevention strategies for pressure injury in adult hospitalized burn patients. Methods: A bibliometric approach was used. Systematic searches were carried out to retrieve the published evidence of prevention strategies for pressure injury in adult hospitalized burn patients in the official websites of relevant academic organizations such as International Society for Burn injury, American Burn Association, and Japanese Dermatology Association, National Pressure Injury Advisory Panel, European Pressure Injury Advisory Panel, Pan Pacific Pressure Injury Alliance International Guidelines Website, foreign language databases such as UpToDate, BMJ Best Practice, MedSci, Joanna Briggs Institute Evidence-Based Practice Database, Cochrane Library, Web of Science, Embase, and PubMed, and Chinese databases such as China Biology Medicine disc, China National Knowledge Infrastructure, Wanfang Database, and China Clinical Guidelines Library. The literature types include clinical decision-making, evidence summary, guidelines, systematic review, and expert consensus. The search time was till February 21st, 2023. Two researchers independently screened the literature and evaluated the quality, and other researchers extracted and graded the evidence according to the topic. Results: A total of 10 papers were included, including 6 evidence summaries, 3 guidelines, and 1 expert consensus, all with high literature quality. After extracting evidence and classifying, 27 pieces of best evidences were summarized from three aspects, including prevention training and supervision, risk assessment, and prevention measures of pressure injury. Conclusions: A total of 27 pieces of best evidences of prevention strategies for pressure injury in adult hospitalized burn patients were summarized from 3 aspects. Medical workers can follow the best evidence and give personalized prevention strategies according to the specific condition of adult hospitalized burn patients to reduce the incidence of pressure injury.

目的:总结成年住院烧伤患者压力损伤预防策略的最佳证据。方法:采用文献计量学方法。在国际烧伤学会、美国烧伤协会、日本皮肤病学会、国家压力损伤咨询小组、,欧洲压力损伤咨询小组、泛太平洋压力损伤联盟国际指南网站、UpToDate、BMJ Best Practice、MedSci、Joanna Briggs Institute循证实践数据库、Cochrane Library、Web of Science、Embase和PubMed等外语数据库,以及中国生物医学光盘、中国国家知识基础设施、,万方数据库和中国临床指南库。文献类型包括临床决策、证据总结、指南、系统综述和专家共识。搜索时间为2023年2月21日。两名研究人员对文献进行独立筛选并评估质量,其他研究人员根据主题提取证据并进行评分。结果:共收录论文10篇,其中证据总结6篇,指南3篇,专家共识1篇,文献质量较高。经过提取证据和分类,从预防培训和监督、风险评估、压力损伤预防措施三个方面总结出27条最佳证据。结论:从3个方面总结了27条预防成人住院烧伤患者压力损伤策略的最佳证据。医务工作者可以遵循最佳证据,根据成年住院烧伤患者的具体情况,给出个性化的预防策略,以降低压力损伤的发生率。
{"title":"[Best evidence summary of prevention strategies for pressure injury in adult hospitalized burn patients].","authors":"L Q Han, M Y Shen, X Y Tang, P X Wan, L D Lao, T He","doi":"10.3760/cma.j.cn501225-20230328-00101","DOIUrl":"10.3760/cma.j.cn501225-20230328-00101","url":null,"abstract":"<p><p><b>Objective:</b> To summarize the best evidence of prevention strategies for pressure injury in adult hospitalized burn patients. <b>Methods:</b> A bibliometric approach was used. Systematic searches were carried out to retrieve the published evidence of prevention strategies for pressure injury in adult hospitalized burn patients in the official websites of relevant academic organizations such as International Society for Burn injury, American Burn Association, and Japanese Dermatology Association, National Pressure Injury Advisory Panel, European Pressure Injury Advisory Panel, Pan Pacific Pressure Injury Alliance International Guidelines Website, foreign language databases such as UpToDate, BMJ Best Practice, MedSci, Joanna Briggs Institute Evidence-Based Practice Database, Cochrane Library, Web of Science, Embase, and PubMed, and Chinese databases such as China Biology Medicine disc, China National Knowledge Infrastructure, Wanfang Database, and China Clinical Guidelines Library. The literature types include clinical decision-making, evidence summary, guidelines, systematic review, and expert consensus. The search time was till February 21<sup>st</sup>, 2023. Two researchers independently screened the literature and evaluated the quality, and other researchers extracted and graded the evidence according to the topic. <b>Results:</b> A total of 10 papers were included, including 6 evidence summaries, 3 guidelines, and 1 expert consensus, all with high literature quality. After extracting evidence and classifying, 27 pieces of best evidences were summarized from three aspects, including prevention training and supervision, risk assessment, and prevention measures of pressure injury. <b>Conclusions:</b> A total of 27 pieces of best evidences of prevention strategies for pressure injury in adult hospitalized burn patients were summarized from 3 aspects. Medical workers can follow the best evidence and give personalized prevention strategies according to the specific condition of adult hospitalized burn patients to reduce the incidence of pressure injury.</p>","PeriodicalId":24004,"journal":{"name":"Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns","volume":"39 9","pages":"867-873"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11630381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41100755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Curative effects of medial plantar free flap in reconstructing electric burn wound and scar contracture in the palm]. [足底内侧游离皮瓣修复手掌电烧伤及瘢痕挛缩的疗效]。
Q3 Medicine Pub Date : 2023-09-20 DOI: 10.3760/cma.j.cn501225-20230601-00197
F Han, X K Yang, T He, L X Wang, N Zhang, J T Han

Objective: To explore the curative effects of medial plantar free flap in reconstructing electric burn wound and scar contracture in the palm. Methods: A retrospective observational study was conducted. From January 2020 to January 2023, 6 patients with electric burn wounds or scar contracture in the palm who met the inclusion criteria were admitted to the First Affiliated Hospital of Air Force Medical University, including 5 males and 1 female, aged 35 to 55 years. The wound area was 5.0 cm×3.0 cm-8.0 cm×7.0 cm after the debridement of electric burn wounds or resection of scar in the palm. The medial plantar free flap anastomosed with cutaneous nerve was used for wound reconstruction, with flap area of 5.5 cm×3.5 cm-8.5 cm×7.5 cm. The wound in the donor site was repaired with transplantation of abdominal full-thickness skin graft. After surgery, the survival of flaps and skin grafts were observed, the shape and texture of flap and the recovery of donor site of flap were observed, and the holding function of the affected hand was assessed. At the last follow-up, the two-point discrimination distance of flap was measured, the sensory recovery of flap was evaluated with the trial standard for the evaluation of the functions of the upper limbs of the Hand Surgery Society of the Chinese Medical Association, and the function recovery of flap was evaluated by post-surgery flap function evaluation scale. Results: After surgery, 5 flaps survived well, while the distal part of 1 flap was partially necrotic, which was repaired by medium-thickness skin graft from lateral thigh after debridement. All the skin grafts at the donor sites survived well. During follow-up of 3 to 24 months, the flap was not bloated, the texture and color were good, the match with the surrounding tissue was high, with no obvious scar contracture occurred at the donor site. The affected hand had good holding function. At the last follow-up, the two-point discrimination distance of flap was 6-8 mm, the flap sensation recovery was as follows: 5 flaps recovered to grade S3+, 1 flap recovered to grade S3, and the functional evaluation of flaps was excellent in 5 cases and good in 1 case. The patients basically returned to normal life and work. Conclusions: The medial plantar free flap with cutaneous nerve anastomosis has many advantages, such as high matching degree of appearance, good sensory recovery, and holding function of the affected hand. It is an ideal choice for the reconstruction of the electric burn wound and scar contracture in the palm.

目的:探讨足底内侧游离皮瓣修复手掌电烧伤及瘢痕挛缩的疗效。方法:采用回顾性观察研究。2020年1月至2023年1月,空军医科大学第一附属医院收治6例符合纳入标准的电烧伤或手掌瘢痕挛缩患者,其中男5例,女1例,年龄35-55岁。电烧伤创面清创或手掌瘢痕切除后,创面面积为5.0cm×3.0cm~8.0cm×7.0cm。采用吻合皮神经的足底内侧游离皮瓣进行创面重建,皮瓣面积5.5cm×3.5cm~8.5cm×7.5cm,供区创面采用腹部全厚皮片移植修复。术后观察皮瓣和皮肤移植物的存活情况,观察皮瓣的形状和质地以及皮瓣供区的恢复情况,并评估患手的握持功能。在最后一次随访中,测量皮瓣两点辨别距离,用中华医学会手外科学会上肢功能评定试验标准评定皮瓣感觉恢复情况,用术后皮瓣功能评定量表评定皮瓣功能恢复情况。结果:术后5个皮瓣成活良好,1个皮瓣远端部分坏死,清创后用股外侧中厚皮片修复。所有移植部位的皮肤均存活良好。随访3~24个月,皮瓣无肿胀,质地、色泽良好,与周围组织匹配度高,供区无明显瘢痕挛缩。患手握持功能良好。在最后一次随访中,皮瓣的两点判别距离为6-8mm,皮瓣感觉恢复情况如下:5个皮瓣恢复到S3+级,1个皮瓣恢复为S3级,5例皮瓣功能评价优,1例皮瓣感觉良好。患者基本恢复了正常的生活和工作。结论:吻合皮神经的足底内侧游离皮瓣具有外形匹配度高、感觉恢复良好、对患手握持功能好等优点。它是重建手掌电烧伤和瘢痕挛缩的理想选择。
{"title":"[Curative effects of medial plantar free flap in reconstructing electric burn wound and scar contracture in the palm].","authors":"F Han, X K Yang, T He, L X Wang, N Zhang, J T Han","doi":"10.3760/cma.j.cn501225-20230601-00197","DOIUrl":"10.3760/cma.j.cn501225-20230601-00197","url":null,"abstract":"<p><p><b>Objective:</b> To explore the curative effects of medial plantar free flap in reconstructing electric burn wound and scar contracture in the palm. <b>Methods:</b> A retrospective observational study was conducted. From January 2020 to January 2023, 6 patients with electric burn wounds or scar contracture in the palm who met the inclusion criteria were admitted to the First Affiliated Hospital of Air Force Medical University, including 5 males and 1 female, aged 35 to 55 years. The wound area was 5.0 cm×3.0 cm-8.0 cm×7.0 cm after the debridement of electric burn wounds or resection of scar in the palm. The medial plantar free flap anastomosed with cutaneous nerve was used for wound reconstruction, with flap area of 5.5 cm×3.5 cm-8.5 cm×7.5 cm. The wound in the donor site was repaired with transplantation of abdominal full-thickness skin graft. After surgery, the survival of flaps and skin grafts were observed, the shape and texture of flap and the recovery of donor site of flap were observed, and the holding function of the affected hand was assessed. At the last follow-up, the two-point discrimination distance of flap was measured, the sensory recovery of flap was evaluated with the trial standard for the evaluation of the functions of the upper limbs of the Hand Surgery Society of the Chinese Medical Association, and the function recovery of flap was evaluated by post-surgery flap function evaluation scale. <b>Results:</b> After surgery, 5 flaps survived well, while the distal part of 1 flap was partially necrotic, which was repaired by medium-thickness skin graft from lateral thigh after debridement. All the skin grafts at the donor sites survived well. During follow-up of 3 to 24 months, the flap was not bloated, the texture and color were good, the match with the surrounding tissue was high, with no obvious scar contracture occurred at the donor site. The affected hand had good holding function. At the last follow-up, the two-point discrimination distance of flap was 6-8 mm, the flap sensation recovery was as follows: 5 flaps recovered to grade S3<sup>+</sup>, 1 flap recovered to grade S3, and the functional evaluation of flaps was excellent in 5 cases and good in 1 case. The patients basically returned to normal life and work. <b>Conclusions:</b> The medial plantar free flap with cutaneous nerve anastomosis has many advantages, such as high matching degree of appearance, good sensory recovery, and holding function of the affected hand. It is an ideal choice for the reconstruction of the electric burn wound and scar contracture in the palm.</p>","PeriodicalId":24004,"journal":{"name":"Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns","volume":"39 9","pages":"820-825"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11630327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41111745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of tibial second toe free flap bridged with blood flow and nerve in the treatment of severe flexion contracture of the proximal interphalangeal joint]. [带血流和神经桥接的胫骨第二趾游离皮瓣治疗近端指间关节严重屈曲挛缩的疗效]。
Q3 Medicine Pub Date : 2023-08-20 DOI: 10.3760/cma.j.cn501225-20220707-00286
K Wang, G Z Jin, Z C Teng, C W Ge, Z J Liu, J H Ju, S Dong, Q Wang, Y D Li
<p><p><b>Objective:</b> To investigate the effects of tibial second toe free flap bridged with blood flow and nerve in the treatment of severe flexion contracture of the proximal interphalangeal joint. <b>Methods:</b> A retrospective observational study was conducted. From March 2013 to October 2019, 9 patients with severe flexion contracture (type Ⅲ) of the proximal interphalangeal joint after trauma operation, conforming to the inclusion criteria, were hospitalized in Suzhou Ruihua Orthopaedic Hospital, including 5 males and 4 females, aged from 17 to 62 years. After the contracture tissue affecting the extension of the proximal interphalangeal joint was cut off, and the scar tissue was resected, the size of the volar wound near the proximal interphalangeal joint in extended position was 2.0 cm×1.0 cm-2.5 cm×1.5 cm, with the length of proper digital artery and nerve defect being 1.0-1.5 cm. A free flap of the same size as the wound was cut from the tibial side of the second toe and transplanted to repair the wound, and the defective proper digital artery and nerve was repaired by bridging with the tibial proper plantar digital artery and nerve of about 1.5 cm in length. The full-thickness skin graft was taken from the proximal tibial side of the lower leg to repair the wound at flap donor site. The wound at skin graft donor site was sutured directly. The survival of flap and skin graft was observed after operation. The patients were followed up, and at the last follow-up, the recovery of the affected finger and the second toe, including the donor and recipient areas were observed, the two-point discrimination distances of the flap repaired site and the pulp of the affected finger were observed and measured at the same time, the blood flow patency of bridged vessel of the affected finger was examined by Allen test, and the function of the proximal interphalangeal joint of the affected finger was evaluated according to Chinese Medical Association's standard for the range of motion of proximal interphalangeal joint. <b>Results:</b> The flaps and skin grafts survived smoothly after operation. The follow-up after operation lasted for 5 to 22 months, with a mean of 10 months. At the last follow-up, the flap repaired site had good shape, good color and texture, with the two-point discrimination distance being 9-12 mm, and the two-point discrimination distance of the pulp of the affected finger was 6-10 mm; the Allen test results of the affected fingers were all negative (i.e., the bridged vessels had good blood flow patency), with no recurrence of flexion contracture, and the function of the proximal interphalangeal joint was evaluated as excellent; the skin graft area of the second toe was not ruptured but was a little pigmented, and the flexion and extension activities of toe were good. <b>Conclusions:</b> The tibial second toe free flap bridged with blood flow and nerve has reliable therapeutic effect in the treatment of severe flexion contracture
目的:探讨带血供和神经桥接的胫骨第二趾游离皮瓣治疗严重指间关节屈曲挛缩症的疗效。方法:采用回顾性观察研究。2013年3月至2019年10月,苏州瑞华骨科医院收治9例符合纳入标准的外伤后近端指间关节严重屈曲挛缩(Ⅲ型)患者,其中男5例,女4例,年龄17~62岁。切除影响近端指间关节伸展的挛缩组织,切除瘢痕组织后,伸展位置指间关节近端掌侧伤口大小为2.0cm×1.0cm~2.5cm×1.5cm,指固有动脉和神经缺损长度为1.0-1.5cm。从第二脚趾的胫骨侧切下与伤口大小相同的游离皮瓣并移植以修复伤口,通过与长度约1.5cm的胫骨指足底固有动脉和神经桥接来修复有缺陷的指固有动脉和神经元。从小腿胫骨近端取全厚皮片,修复皮瓣供区创面。直接缝合供皮部位的伤口。术后观察皮瓣和皮片的成活情况。对患者进行随访,在最后一次随访时,观察患指和第二趾的恢复情况,包括供体和受体区域,同时观察和测量皮瓣修复部位和患指牙髓的两点判别距离,采用Allen试验检测患指桥接血管的血流通畅性,并根据中华医学会近端指间关节活动范围标准评价患指近端指指间关节的功能。结果:术后皮瓣及皮片均顺利成活。术后随访5~22个月,平均10个月。最后一次随访时,皮瓣修复部位形状好,颜色质地好,两点辨别距离9-12mm,患指牙髓两点辨别距离6-10mm;患指Allen试验结果均为阴性(即桥接血管血流通畅性良好),屈曲挛缩无复发,近端指间关节功能评价为优良;第二足趾植皮区未破裂,但有少量色素沉着,足趾屈伸活动良好。结论:带血流和神经桥接的胫骨第二趾游离皮瓣治疗近端指间关节屈曲挛缩症疗效可靠,皮瓣修复区颜色和质地良好。桥接修复严重收缩的指固有动脉和神经,有利于改善指体的血液供应,重建感觉。
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引用次数: 0
[Mechanism and prevention and treatment strategy of progressive injury in high-voltage electric burns]. 【高压电烧伤进行性损伤的机制及防治策略】。
Q3 Medicine Pub Date : 2023-08-20 DOI: 10.3760/cma.j.cn501225-20230331-00107
Q F Zhang, J W Hao

High-voltage electric burn is one of burns that can cause severe damages to tissue and organs. Clinically, progressive injury in high-voltage electric burns is a key pathological change that affects the level of amputation and the success rate of treatment. At present, the exact definition and mechanism of progressive injury in high-voltage electric burns have not been elucidated, and the clinical treatment is mainly symptomatic treatment. Relevant research data on the mechanism and treatment of progressive injury in high-voltage electric burns are lacking. This paper analyzes and summarizes the mechanism, diagnosis, treatment, and common outcome of progressive injury in high-voltage electric burns, and provides a reference for the mechanism research, clinical diagnosis and treatment of progressive injury in high-voltage electric burns.

高压电烧伤是一种可对组织和器官造成严重损伤的烧伤。临床上,高压电烧伤的进行性损伤是影响截肢水平和治疗成功率的关键病理变化。目前,高压电烧伤进行性损伤的确切定义和机制尚未阐明,临床治疗以对症治疗为主。关于高压电烧伤进行性损伤的机制和治疗方法,缺乏相关的研究资料。本文对高压电烧伤进行性损伤的机制、诊断、治疗及常见转归进行了分析和总结,为高压电烧伤的进行性损伤机制研究、临床诊断和治疗提供参考。
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引用次数: 0
[A case with giant ulcer caused by skin diffuse large B-cell lymphoma in the axilla]. [一例腋窝皮肤弥漫性大B细胞淋巴瘤引起的巨大溃疡]。
Q3 Medicine Pub Date : 2023-08-20 DOI: 10.3760/cma.j.cn501225-20220331-00116
F Liu, W Zhang, W G Xie, L Chen, Z Li

In May 16th, 2019, a male patient (aged 51 years) with a rare giant ulcer caused by skin diffuse large B-cell lymphoma in the axilla was admitted to Tongren Hospital of Wuhan University & Wuhan Third Hospital, and the ulcer wound was confirmed by biopsy and immunohistochemical analysis after extensive excision. Ultimately, a good prognosis was obtained by transplantation of flap and skin graft in combination with radiotherapy and chemotherapy.

2019年5月16日,一名男性患者(51岁)因腋窝皮肤弥漫性大B细胞淋巴瘤引起的罕见巨大溃疡入住武汉大学同仁医院和武汉市第三医院,经广泛切除,经活检和免疫组织化学分析证实溃疡伤口。最终,通过皮瓣移植和皮肤移植结合放疗和化疗获得了良好的预后。
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引用次数: 0
[Research advances on post-burn cognitive disorders and its mechanism]. [烧伤后认知障碍及其机制研究进展]。
Q3 Medicine Pub Date : 2023-08-20 DOI: 10.3760/cma.j.cn501225-20221117-00492
Y Luo, G P Liang

Cognitive disorders after burns is an important problem that cannot be ignored in the diagnosis and treatment of burn patients. Its mechanism may be related to the activation of inflammatory response, destruction of the blood-brain barrier, hypothalamic-pituitary-adrenal axis imbalance, nerve cell changes, etc. Mechanism-specific prevention and treatment will be the best choice to reduce post-burn cognitive disorders in the future. This review introduces the research advances in epidemiology, risk factors, possible pathogenesis, diagnosis, treatment, and prevention of cognitive disorders in burn patients, in order to provide a reference for timely and accurate assessment, treatment, and prevention of cognitive disorders in burn patients.

烧伤后认知障碍是烧伤患者诊断和治疗中不可忽视的重要问题。其机制可能与炎症反应的激活、血脑屏障的破坏、下丘脑-垂体-肾上腺轴失衡、神经细胞变化等有关。机制特异性预防和治疗将是未来减少烧伤后认知障碍的最佳选择。本文综述了烧伤患者认知障碍的流行病学、危险因素、可能的发病机制、诊断、治疗和预防等方面的研究进展,以期为烧伤患者及时、准确地评估、治疗和防治认知障碍提供参考。
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引用次数: 0
[Treatment methods of upper limbs with destructive electric burns and its clinical efficacy]. [上肢破坏性电烧伤的治疗方法及临床疗效]。
Q3 Medicine Pub Date : 2023-08-20 DOI: 10.3760/cma.j.cn501225-20230530-00188
W Zhang, L Chen, F Yang, W D Zhang, F Liu, W G Xie
<p><p><b>Objective:</b> To investigate the treatment methods of upper limbs with destructive electric burns and its clinical efficacy. <b>Methods:</b> A retrospective observational study was conducted. From July 2014 to December 2020, 20 male patients with destructive electric burns in upper limbs who met the inclusion criteria were admitted to Tongren Hospital of Wuhan University & Wuhan Third Hospital, aged from 21 to 57 years, of whom 7 patients underwent emergency surgery, and a total of 20 affected limbs were treated with limb salvage. The necrotic bone was resected in 5 affected limbs, the residual hand and wrist at the distal end of left affected limb was replanted to the residual end of the right forearm in one patient in a cross heterotopic way, and short reduction and replantation after osteotomy were performed for two affected limbs with distal ulnar and radial necrosis. After thorough debridement, the area of wound proposed to be repaired by tissue flap was from 12 cm×7 cm to 58 cm×13 cm. According to the size and distribution of wound, the wounds of 2 affected limbs were repaired by transplantation of pedicled latissimus dorsi myocutaneous flap and free groin flap with vascular anastomosis. The wounds of the remaining 17 affected limbs were repaired with the transplantation of free latissimus dorsi myocutaneous flap, anterolateral thigh flaps, and paraumbilical perforator flap, with 10 affected limbs with larger wounds being jointly transplanted with the groin flap or the paraumbilical perforator flap on the other side. The total grafted tissue flap area was 20 cm×8 cm to 52 cm×20 cm. During tissue flap transplantation, according to the length of blood vessel defect in the affected limb, the distal artery of the affected limb was bridged with the distal part of flap vascular pedicle, undamaged vein on the affected side, superficial vein of abdominal wall, and great saphenous vein, etc., in 14 affected limbs, and the great saphenous vein was grafted in 3 of them with impeded distal return for recanalization of distal limb veins. The wound in the donor area was repaired by direct suture or grafting with split-thickness scalp. After the wound was basically healed, the functional rehabilitation training was started gradually, and the functional reconstruction and scar rectification surgery were started 3 months after tissue flap transplantation. The survival of tissue flaps/skin grafts, wound healing, limb salvage, and follow-up status after surgery were recorded. At the last follow-up, the function of the successfully salvaged limb was evaluated and scored by the disabilities of the arm, shoulder and hand (DASH) scoring scale. <b>Results:</b> After surgery, the grafted tissue flap in the affected limb and the skin grafts transplanted on the wound at flap donor site survived, and wounds at the recipient and donor sites healed well. Two affected limbs had distal necrosis within 10 days after tissue flap transplantation, and the middle and
目的:探讨上肢破坏性电烧伤的治疗方法及临床疗效。方法:采用回顾性观察研究。2014年7月至2020年12月,武汉大学同仁医院和武汉市第三医院收治了20名符合纳入标准的男性上肢破坏性电烧伤患者,年龄在21-57岁之间,其中7名患者接受了紧急手术,共有20名患肢接受了保肢治疗。对5例患肢进行坏死骨切除,1例患者将左患肢远端残手、残腕交叉异位再植至右前臂残端,对2例尺骨、桡骨远端坏死的患肢进行截骨后短复位再植。经彻底清创后,建议用组织瓣修复的伤口面积为12cm×7cm至58cm×13cm。根据伤口的大小和分布,采用带蒂背阔肌皮瓣和带血管吻合的腹股沟游离皮瓣移植修复2例患肢的伤口。其余17条患肢采用游离背阔肌肌皮瓣、股前外侧皮瓣、脐旁穿支皮瓣移植修复,10条创面较大的患肢采用另一侧腹股沟皮瓣或脐旁穿支皮瓣联合移植。移植的组织瓣总面积为20cm×8cm至52cm×20cm。在组织瓣移植过程中,根据患肢血管缺损的长度,14条患肢的患肢远端动脉与皮瓣血管蒂远端、患侧未损伤静脉、腹壁浅静脉、大隐静脉等桥接,其中3例移植大隐静脉,远端返流不畅,用于肢体远端静脉再通。供区创面采用直接缝合或头皮分厚移植修复。伤口基本愈合后,逐渐开始功能康复训练,组织瓣移植3个月后开始功能重建和瘢痕矫正手术。记录组织瓣/皮肤移植物的存活率、伤口愈合、肢体挽救和手术后的随访情况。在最后一次随访中,通过手臂、肩膀和手部残疾(DASH)评分表对成功挽救的肢体的功能进行评估和评分。结果:术后,移植于患肢的组织瓣和皮瓣供区创面的皮片均成活,供区和受区创面愈合良好。两条患肢在组织瓣移植后10天内出现远端坏死,前臂中上部被截肢。其余18条患肢均获成功挽救(包括缩短再植和交叉异位再植)。在6~48个月的随访中,5例成功挽救的患肢在组织瓣移植后3~18个月出现残余肌腱和骨组织无菌溶解,经手术清创结合真空密封引流治疗后逐渐愈合。在最后一次随访中,两个患肢的残端在截肢后愈合良好;成功抢救的18条患肢均存活良好,其中8条患肢手指屈伸功能和拇指对侧功能恢复良好,能独立完成日常活动,9只患肢恢复了部分活动能力,可以在对侧上肢或辅助装置的帮助下完成穿衣、吃饭等日常活动,1只患肢无功能。在最后一次随访中,成功挽救的18条患肢的DASH评分表功能评分范围为30.0-100。结论:及时进行手术清创,正确处理损伤的骨组织,有效桥接血管重建患肢远端动脉,使用富血组织瓣修复伤口,结合早期康复和功能恢复治疗,有利于抢救有破坏性电烧伤的上肢,改善患肢功能。
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Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns
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