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2021 3rd Novel Intelligent and Leading Emerging Sciences Conference (NILES)最新文献

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High Performance Machine Learning Models for Functional Verification of Hardware Designs 硬件设计功能验证的高性能机器学习模型
Pub Date : 2021-10-23 DOI: 10.1109/NILES53778.2021.9600502
Khaled A. Ismail, M. A. E. Ghany
Fast and accurate Machine Learning (ML) models for predicting input stimulus in verification testbenches are proposed in this paper. Multiple (ML) models: Artificial Neural Network (ANN), Deep Neural Network (DNN), Support Vector Regression (SVR) and Decision Trees (DT) are examined to constrain randomization of input values to hit the planned coverage metrics. Accuracy of the models is measured using (ML) evaluation metrics such as: Mean Squared Error (MSE) and (R2 score). Training time required for each (ML) model is calculated and compared. Investigated (ML) models show an average improvement of 63.5% in the number of simulation cycles needed to reach full coverage closure compared to existing work. Comparative analysis between the models shows that (DT) is the most suitable (ML) model for a functional verification environment, due to its high accuracy and low training time required.
本文提出了一种快速准确的机器学习模型,用于预测验证测试台中输入的刺激。研究了多个(ML)模型:人工神经网络(ANN)、深度神经网络(DNN)、支持向量回归(SVR)和决策树(DT),以约束输入值的随机化,以达到计划的覆盖指标。使用(ML)评估指标,如:均方误差(MSE)和(R2评分)来测量模型的准确性。计算并比较每个(ML)模型所需的训练时间。调查(ML)模型显示,与现有工作相比,达到全覆盖关闭所需的模拟周期数量平均提高了63.5%。模型之间的对比分析表明,(DT)模型具有较高的准确率和较低的训练时间,是最适合功能验证环境的(ML)模型。
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引用次数: 1
Benchmarking of Antimicrobial Resistance Gene Detection Tools in Assembled Bacterial Whole Genomes 组装细菌全基因组耐药基因检测工具的标杆研究
Pub Date : 2021-10-23 DOI: 10.1109/NILES53778.2021.9600515
E. Abdelrazik, Mariam Oweda, M. El-Hadidi
Antimicrobial resistance (AMR) is one of the ten dangers threatening our world, according to the world health organization (WHO). Nowadays, there are plenty of electronic microbial genomics and metagenomics data records that represent host-associated microbiomes. These data introduce new insights and a comprehensive understanding of the current antibiotic resistance threats and the upcoming resistance outbreak. Many bioinformatics tools have been developed to detect the AMR genes based on different annotated databases of bacterial whole genome sequences (WGS). The number and structure of databases used may affect prediction quality. Herein, we aim to check the performance of four AMR gene detection tools and characterize the detection quality by comparing predicted results to reference antibiotic susceptibility test (AST) data. This may enhance the precise in-silico prediction of resistance phenotype and reduce false-positive predictions, which lead to more biologically relevant results. Four AMR gene detection tools; AMRFinder, ABRicate, ResFinder, and SraX are used for the benchmarking using Salmonella enterica isolates (n=104) retrieved from National Center for Biotechnology Information (NCBI) Assembly Database in July 2021. Performance is checked in terms of accuracy, precision, and specificity for each tool. Pearson x2 test is used to compare predicted results with antibiotic susceptibility testing (true results). All performance measures are assessed via scikit-learn package 0.21.3 and R software V 4.0.3. The highest accuracy was achieved by AMRFinder (0.89), while ResFinder had the highest precision score (0.93) and ABRicate has the lowest time and memory consumption. On the other hand, ResFinder's results confirmed the null hypothesis of the Pearson x2 test. We conclude that ResFinder is the best tool where its results have the tiniest difference compared to the phenotypic antibiotic susceptibility (true results).
根据世界卫生组织(WHO)的报告,抗菌素耐药性(AMR)是威胁我们世界的十大危险之一。目前,已有大量代表宿主相关微生物组的电子微生物基因组学和宏基因组学数据记录。这些数据提供了对当前抗生素耐药性威胁和即将发生的耐药性暴发的新见解和全面理解。基于不同的细菌全基因组序列(WGS)注释数据库,已经开发了许多生物信息学工具来检测AMR基因。所用数据库的数量和结构可能会影响预测质量。在此,我们的目的是检查四种AMR基因检测工具的性能,并通过将预测结果与参考抗生素敏感性试验(AST)数据进行比较来表征检测质量。这可能会提高耐药表型的精确计算机预测,减少假阳性预测,从而导致更多生物学相关的结果。四种AMR基因检测工具;使用AMRFinder、ABRicate、ResFinder和SraX对2021年7月从国家生物技术信息中心(NCBI)组装数据库检索的肠沙门氏菌分离株(n=104)进行基准测试。根据每个工具的准确性、精密度和特异性来检查性能。使用Pearson x2检验比较预测结果与抗生素药敏试验(真实结果)。所有性能指标均通过scikit-learn软件包0.21.3和R软件v4.0.3进行评估。AMRFinder的准确率最高(0.89),ResFinder的准确率最高(0.93),ABRicate的时间和内存消耗最低。另一方面,ResFinder的结果证实了Pearson x2检验的零假设。我们的结论是,ResFinder是最好的工具,其结果与表型抗生素敏感性(真实结果)相比差异最小。
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引用次数: 1
Navigation of an n-link Revolute Robotic Arm via Hierarchal Landmarks 基于层次地标的n连杆旋转机械臂导航
Pub Date : 2021-10-23 DOI: 10.1109/NILES53778.2021.9600539
Ravinesh Chand, Sandeep Kumar, R. P. Chand
This paper presents a dynamic n-link revolute robotic arm that can perform a sequence of tasks and navigate via hierarchal landmarks to its target. The stability condition with multiple Lyapunov functions for switched systems is considered. The multiple Lyapunov functions are formulated from the Lyapunov-based Control Scheme (LbCS) as a tool for analyzing Lyapunov stability. A new set of switched nonlinear, time-invariant, continuous, and stabilizing velocity controllers of the proposed Rn robotic arm are developed.
本文提出了一种动态n连杆旋转机械臂,它可以执行一系列任务并通过分层地标导航到目标。研究了具有多个Lyapunov函数的切换系统的稳定性条件。基于Lyapunov的控制方案(LbCS)形成了多个Lyapunov函数,作为分析Lyapunov稳定性的工具。研制了一套新型的切换非线性定常连续稳定速度控制器。
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引用次数: 9
期刊
2021 3rd Novel Intelligent and Leading Emerging Sciences Conference (NILES)
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