{"title":"Para-testicular Sarcoma: An Extreme Rarity","authors":"Anurag Mishra, Tridibes Mandal","doi":"10.4103/jme.jme_138_22","DOIUrl":"https://doi.org/10.4103/jme.jme_138_22","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"64 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140436898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The competency-based medical education new curriculum stresses on the foundation course at the beginning of the MBBS programme, with an objective to orient the students on new knowledge and skills that will aid them in adapting to the new professional environment, providing the opportunity for faculty and peer interactions and sensitisation towards various teaching–learning methods. The Aim of the study was to analyse the student’s feedback on the foundation course and to determine the level of satisfaction of the learners towards the course. This was a programme evaluation of foundation course for newly joined MBBS students in Mamata Academy of Medical Sciences, Hyderabad, Telangana, India, during December from 12th to 19th for 7 days. On feedback analysis, around 90% of the students were satisfied with all the sessions and the students have expressed a high level of satisfaction towards the sessions of teamwork, leadership skills, interpersonal communication skills, Basic Life Support (BLS), first aid, field visit and Indian Medical Graduate (IMG) goals. A statistically significant difference between the mean scores of pre and post test was found. The overall feedback on the foundation course was satisfactory. Students have gladly received the foundation course and they were well sensitised by the topics covered and activities conducted. There was a significant improvement in their assessment scores. Thus, the impact of the foundation course will definitely help in accomplishing the goals of IMG effectively.
{"title":"Impact of Foundation Course on First MBBS Students and Their Level of Satisfaction – A Programme Evaluation","authors":"M. S. Lakshmi, P. Moses, Sulakshana Sony Cheemala","doi":"10.4103/jme.jme_48_23","DOIUrl":"https://doi.org/10.4103/jme.jme_48_23","url":null,"abstract":"\u0000 \u0000 \u0000 The competency-based medical education new curriculum stresses on the foundation course at the beginning of the MBBS programme, with an objective to orient the students on new knowledge and skills that will aid them in adapting to the new professional environment, providing the opportunity for faculty and peer interactions and sensitisation towards various teaching–learning methods.\u0000 \u0000 \u0000 \u0000 The Aim of the study was to analyse the student’s feedback on the foundation course and to determine the level of satisfaction of the learners towards the course.\u0000 \u0000 \u0000 \u0000 This was a programme evaluation of foundation course for newly joined MBBS students in Mamata Academy of Medical Sciences, Hyderabad, Telangana, India, during December from 12th to 19th for 7 days.\u0000 \u0000 \u0000 \u0000 On feedback analysis, around 90% of the students were satisfied with all the sessions and the students have expressed a high level of satisfaction towards the sessions of teamwork, leadership skills, interpersonal communication skills, Basic Life Support (BLS), first aid, field visit and Indian Medical Graduate (IMG) goals. A statistically significant difference between the mean scores of pre and post test was found.\u0000 \u0000 \u0000 \u0000 The overall feedback on the foundation course was satisfactory. Students have gladly received the foundation course and they were well sensitised by the topics covered and activities conducted. There was a significant improvement in their assessment scores. Thus, the impact of the foundation course will definitely help in accomplishing the goals of IMG effectively.\u0000","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"27 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arjun Kumar Singhal, M. H. Siddiqui, Shalini Goldar, Naveen Kumar, Sonu Kumari Agrawal
{"title":"National Medical Commission’s Generic Drug Policy: A Boon or a Bane for RMPs and Public Health?","authors":"Arjun Kumar Singhal, M. H. Siddiqui, Shalini Goldar, Naveen Kumar, Sonu Kumari Agrawal","doi":"10.4103/jme.jme_154_23","DOIUrl":"https://doi.org/10.4103/jme.jme_154_23","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"28 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Kulshreshtha, Osama Neyaz, Shahena Begum, Raj Kumar Yadav, K. Deepak
Hyperbaric oxygen therapy (HBOT) is an adjunctive treatment for chronic pain. The current study aimed to perform a systematic evaluation and meta-analysis of randomised controlled trials (RCTs) to assess the clinical efficacy and safety of HBOT for pain reduction in fibromyalgia (FM) patients compared to conventional therapy. A systematic search of medical subject headings and keywords associated with HBOT for FM patients was conducted using electronic databases: MEDLINE/ PubMed, Web of Science, Cochrane Library Central Register of Controlled Trials, and Scopus. Google Scholar was also combed to detect likely non-indexed available studies. We also searched manually through reference lists of identified original articles or reviews for relevant articles. The http://www.clinicaltrial.gov was examined for all research protocols being conducted/ planned. The Cochrane Collaboration tool and Higgins and Thompson’s I2 method determined the risk of bias and heterogeneity. The primary outcome was the effect of HBOT on pain; secondary outcomes included adverse effects of HBOT, assessment of the quality of life, functional impairment, psychological symptoms, and sleep quality. The overall quality of evidence was assessed with the GRADE approach. Cochrane RevMan software (version 5.4) was used for data analysis. Results were synthesised through a general summary of the characteristics and findings of each study. We also analysed different HBOT protocols and their outcomes across the studies. Five RCTs enrolling 91 and 89 patients in FM and control groups were included in the present study. HBOT results in decreased tender points (-6.23 (95 % CI: -7.76, -4.71) P < 0.0001), increased pain threshold (0.57 (95% CI: 0.3, 0.83) P < 0.00001) and a decreased Visual Analog scale (VAS) score for pain (-5.31(95 % CI: -8.17, -2.45)). Quality of life, sleep, functional impairment, etc., also improved after HBOT. HBOT is effective in pain and other associated outcomes in FM patients. In FM patients, high-quality evidence in favour of HBOT to improve pain, fatigue, quality of life, sleep, psychological outcomes, etc., is required.
高压氧疗法（HBOT）是一种治疗慢性疼痛的辅助疗法。本研究旨在对随机对照试验（RCTs）进行系统评估和荟萃分析，以评估高压氧疗法与传统疗法相比在减轻纤维肌痛（FM）患者疼痛方面的临床疗效和安全性。我们使用电子数据库对与纤维肌痛患者 HBOT 相关的医学主题词和关键词进行了系统检索：MEDLINE/PubMed、Web of Science、Cochrane Library Central Register of Controlled Trials 和 Scopus。我们还对谷歌学术进行了梳理，以发现可能未被收录的可用研究。我们还通过人工方式在已确定的原始文章或综述的参考文献列表中搜索相关文章。我们在 http://www.clinicaltrial.gov 上检查了所有正在进行/计划进行的研究方案。Cochrane 协作工具以及 Higgins 和 Thompson 的 I2 方法确定了偏倚和异质性风险。主要结果是 HBOT 对疼痛的影响；次要结果包括 HBOT 的不良反应、生活质量评估、功能障碍、心理症状和睡眠质量。证据的总体质量采用 GRADE 方法进行评估。数据分析采用 Cochrane RevMan 软件（5.4 版）。我们对每项研究的特点和结果进行了综合总结。我们还分析了各项研究中不同的 HBOT 方案及其结果。本研究共纳入了五项研究，FM 组和对照组分别有 91 和 89 名患者参加。HBOT 可减少压痛点（-6.23 (95 % CI: -7.76, -4.71) P < 0.0001），提高疼痛阈值（0.57 (95 % CI: 0.3, 0.83) P < 0.00001），减少疼痛的视觉模拟量表（VAS）评分（-5.31(95 % CI: -8.17, -2.45)）。经 HBOT 治疗后，患者的生活质量、睡眠、功能障碍等也有所改善。HBOT 对 FM 患者的疼痛和其他相关症状有效。对于 FM 患者，需要高质量的证据来证明 HBOT 可改善疼痛、疲劳、生活质量、睡眠、心理结果等。
{"title":"Assessment of the Efficacy and Safety of Hyperbaric Oxygen Therapy on Pain in Patients with Fibromyalgia: A Systematic Review and Meta-analysis of Randomised Controlled Studies","authors":"P. Kulshreshtha, Osama Neyaz, Shahena Begum, Raj Kumar Yadav, K. Deepak","doi":"10.4103/jme.jme_102_23","DOIUrl":"https://doi.org/10.4103/jme.jme_102_23","url":null,"abstract":"\u0000 Hyperbaric oxygen therapy (HBOT) is an adjunctive treatment for chronic pain. The current study aimed to perform a systematic evaluation and meta-analysis of randomised controlled trials (RCTs) to assess the clinical efficacy and safety of HBOT for pain reduction in fibromyalgia (FM) patients compared to conventional therapy. A systematic search of medical subject headings and keywords associated with HBOT for FM patients was conducted using electronic databases: MEDLINE/ PubMed, Web of Science, Cochrane Library Central Register of Controlled Trials, and Scopus. Google Scholar was also combed to detect likely non-indexed available studies. We also searched manually through reference lists of identified original articles or reviews for relevant articles. The http://www.clinicaltrial.gov was examined for all research protocols being conducted/ planned. The Cochrane Collaboration tool and Higgins and Thompson’s I2 method determined the risk of bias and heterogeneity. The primary outcome was the effect of HBOT on pain; secondary outcomes included adverse effects of HBOT, assessment of the quality of life, functional impairment, psychological symptoms, and sleep quality. The overall quality of evidence was assessed with the GRADE approach. Cochrane RevMan software (version 5.4) was used for data analysis. Results were synthesised through a general summary of the characteristics and findings of each study. We also analysed different HBOT protocols and their outcomes across the studies. Five RCTs enrolling 91 and 89 patients in FM and control groups were included in the present study. HBOT results in decreased tender points (-6.23 (95 % CI: -7.76, -4.71) P < 0.0001), increased pain threshold (0.57 (95% CI: 0.3, 0.83) P < 0.00001) and a decreased Visual Analog scale (VAS) score for pain (-5.31(95 % CI: -8.17, -2.45)). Quality of life, sleep, functional impairment, etc., also improved after HBOT. HBOT is effective in pain and other associated outcomes in FM patients. In FM patients, high-quality evidence in favour of HBOT to improve pain, fatigue, quality of life, sleep, psychological outcomes, etc., is required.","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"29 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140437672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
India achieved elimination target for leprosy in December 2005. However, many pockets in the country continue to report significant number of cases. The aim of the study was to study the profile of leprosy cases presenting to a tertiary care hospital in North India in post-elimination era. The study was conducted at Hansen’s disease clinic. The study design was a retrospective observational study. Chart review of treatment naive leprosy patients enrolled between 1st January 2018 and 31st December 2019 was done. Data regarding demographic profile, clinical spectrum of leprosy, slit-skin smears (SSSs) and histopathological findings were analysed. Statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS) software version 23 (SPSS Inc., Chicago, IL, USA). Data were statistically described in terms of range, mean ± standard deviation, frequency (number of cases), and relative frequency (percentages). Amongst a total of 115 patients, males (68%, n = 79/115) outnumbered females. Children (<15 years) constituted 0.86% cases (n = 1/115) and 26% cases (n = 30/115) were above 50 years of age. Multibacillary leprosy (73%, n = 84/115) was more common. Borderline lepromatous (41.7%, n = 48/115) was the most common clinical type of leprosy, whereas Grade 2 disability was noted amongst 0.05% (n = 6/115) patients at presentation. SSS were positive in 60% (69/115) cases. The present study showed a significant increase in cases in the older age group and decrease in new cases in children. Furthermore, multibacillary cases outnumbered the paucibacillary cases. Similar trends were reported to be an indicator of decreasing incidence of leprosy in countries that eliminated leprosy. We speculate that India may be entering a phase of decreased community transmission of leprosy. Further, multicentric studies across the country may throw more light.
{"title":"Leprosy in North India in Post-Elimination Era: A Retrospective Study","authors":"N. Hazarika, R. Bhatia, C. Divyalakshmi","doi":"10.4103/jme.jme_40_23","DOIUrl":"https://doi.org/10.4103/jme.jme_40_23","url":null,"abstract":"\u0000 \u0000 \u0000 India achieved elimination target for leprosy in December 2005. However, many pockets in the country continue to report significant number of cases.\u0000 \u0000 \u0000 \u0000 The aim of the study was to study the profile of leprosy cases presenting to a tertiary care hospital in North India in post-elimination era.\u0000 \u0000 \u0000 \u0000 The study was conducted at Hansen’s disease clinic. The study design was a retrospective observational study. Chart review of treatment naive leprosy patients enrolled between 1st January 2018 and 31st December 2019 was done. Data regarding demographic profile, clinical spectrum of leprosy, slit-skin smears (SSSs) and histopathological findings were analysed.\u0000 \u0000 \u0000 \u0000 Statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS) software version 23 (SPSS Inc., Chicago, IL, USA). Data were statistically described in terms of range, mean ± standard deviation, frequency (number of cases), and relative frequency (percentages).\u0000 \u0000 \u0000 \u0000 Amongst a total of 115 patients, males (68%, n = 79/115) outnumbered females. Children (<15 years) constituted 0.86% cases (n = 1/115) and 26% cases (n = 30/115) were above 50 years of age. Multibacillary leprosy (73%, n = 84/115) was more common. Borderline lepromatous (41.7%, n = 48/115) was the most common clinical type of leprosy, whereas Grade 2 disability was noted amongst 0.05% (n = 6/115) patients at presentation. SSS were positive in 60% (69/115) cases.\u0000 \u0000 \u0000 \u0000 The present study showed a significant increase in cases in the older age group and decrease in new cases in children. Furthermore, multibacillary cases outnumbered the paucibacillary cases. Similar trends were reported to be an indicator of decreasing incidence of leprosy in countries that eliminated leprosy. We speculate that India may be entering a phase of decreased community transmission of leprosy. Further, multicentric studies across the country may throw more light.\u0000","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140436528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ravi Gupta, LokeshKumar Saini, Meenu Singh, Yugal Kishore Pant
{"title":"Waking Up to the Importance of Sleep: Need for a National Sleep Health Policy","authors":"Ravi Gupta, LokeshKumar Saini, Meenu Singh, Yugal Kishore Pant","doi":"10.4103/jme.jme_121_23","DOIUrl":"https://doi.org/10.4103/jme.jme_121_23","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"40 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140437485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Kalyani, Kusum K. Rohilla, Pratima Gupta, Saurabh Vashney
{"title":"Tips to Young Researchers: Conflicts of Interest","authors":"C. Kalyani, Kusum K. Rohilla, Pratima Gupta, Saurabh Vashney","doi":"10.4103/jme.jme_120_23","DOIUrl":"https://doi.org/10.4103/jme.jme_120_23","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"139 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140438053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ghost Gall Bladder","authors":"Brij Sharma, V. Bodh, Rajesh Sharma, A. Bhateja","doi":"10.4103/jme.jme_105_23","DOIUrl":"https://doi.org/10.4103/jme.jme_105_23","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"9 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The ongoing COVID-19 pandemic in dengue-endemic countries falls as a huge burden on healthcare infrastructure. Above everything, similar signs and symptoms of diseases caused by the two viruses make diagnosis and treatment more difficult. For this literature review, published articles from January 2020 to March 2023 available in the databases ‘PubMed’, ‘Google Scholar’ and ‘Embase’ have been explored to look at the similarities and differences between dengue and SARS-CoV-2 virus through the lens of genomics, epidemiology, clinical presentation and outcome of patients. The objectives of this study were to draw conclusions about the proposed pathophysiology of the viruses in case of a co-infection and to narrate evidence on outcome associated with the co-infection. Co-infection with dengue and COVID-19 virus can lead to moderate-to-severe morbid conditions; even the outcome could be fatal due to shock, multi-organ failure and stroke.
{"title":"A Narrative Review on Dengue and COVID-19 Co-infection: A Deadly Duo","authors":"Santosh Kumar, Ashutosh Mishra","doi":"10.4103/jme.jme_57_23","DOIUrl":"https://doi.org/10.4103/jme.jme_57_23","url":null,"abstract":"\u0000 The ongoing COVID-19 pandemic in dengue-endemic countries falls as a huge burden on healthcare infrastructure. Above everything, similar signs and symptoms of diseases caused by the two viruses make diagnosis and treatment more difficult. For this literature review, published articles from January 2020 to March 2023 available in the databases ‘PubMed’, ‘Google Scholar’ and ‘Embase’ have been explored to look at the similarities and differences between dengue and SARS-CoV-2 virus through the lens of genomics, epidemiology, clinical presentation and outcome of patients. The objectives of this study were to draw conclusions about the proposed pathophysiology of the viruses in case of a co-infection and to narrate evidence on outcome associated with the co-infection. Co-infection with dengue and COVID-19 virus can lead to moderate-to-severe morbid conditions; even the outcome could be fatal due to shock, multi-organ failure and stroke.","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"32 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. S. Narayanan, Sundaram Loganathan, Barath Lochan, Dinesh Mahalingam
{"title":"RESUSC-O: A Community Cardiopulmonary–Cerebral Resuscitation Provider App","authors":"K. S. Narayanan, Sundaram Loganathan, Barath Lochan, Dinesh Mahalingam","doi":"10.4103/jme.jme_177_23","DOIUrl":"https://doi.org/10.4103/jme.jme_177_23","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"36 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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