Pub Date : 2019-10-02DOI: 10.24217/2530-4984.19s2v1s1.00006
S. Pellicer
{"title":"Experiencia en el uso de biomarcadores farmacogenéticos en la práctica clínica: Hospital La Fe (VALENCIA).","authors":"S. Pellicer","doi":"10.24217/2530-4984.19s2v1s1.00006","DOIUrl":"https://doi.org/10.24217/2530-4984.19s2v1s1.00006","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127767001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-02DOI: 10.24217/2530-4984.19s2v1s1.00008
Cáceres. n, J. A. García-Agúndez
{"title":"El papel de los consorcios en el futuro de la farmacogenética: Proyecto Pharmvar.","authors":"Cáceres. n, J. A. García-Agúndez","doi":"10.24217/2530-4984.19s2v1s1.00008","DOIUrl":"https://doi.org/10.24217/2530-4984.19s2v1s1.00008","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123132922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-02DOI: 10.24217/2530-4984.19s2v1s1.00004
Alicante España. Farmacología Clínica. Departamento de Salud Alican, Alicante España. Neurofarmacología del Dolor, A. Peiró
{"title":"Experiencia en el uso de biomarcadores farmacogenéticos en la práctica clínica: Hospital General de Alicante.","authors":"Alicante España. Farmacología Clínica. Departamento de Salud Alican, Alicante España. Neurofarmacología del Dolor, A. Peiró","doi":"10.24217/2530-4984.19s2v1s1.00004","DOIUrl":"https://doi.org/10.24217/2530-4984.19s2v1s1.00004","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121821866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-12DOI: 10.24217/2530-4984.19V1S1.00012
M. Bravo
Patent ductus arteriosus (PDA) is a common condition of preterm infants and it is associated with significant morbidity and mortality. The best therapeutic option for PDA closure remains controversial. Necrotizing enterocolitis (NEC) and bowel spontaneous perforation have been observed in those infants who received pharmacologic treatment of PDA. Conventional treatment of PDA consists on 3 daily doses of intravenous (iv) ibuprofen in bolus 10-5-5 mg/kg/day. Recently, it has been shown that intravenous continuous infusion of ibuprofen (10-5-5 mg/kg/day) seems to be more effective for PDA closure than the conventional treatment with iv bolus. Our group demonstrated in a recent pilot study that the Echocardiographically guided treatment, EchoG, of PDA when it is compared with the conventional treatment, is feasible and reduces the number of ibuprofen doses. Thus, EchoG treatment potentially reduces the adverse events associated with ibuprofen (i.e lower rate of NEC in the experimental group). This multicenter study will evaluate whether the combination of both experimental therapies (EchoG and iv continuous infusions) reduces the incidence of bowel adverse events (NEC and bowel spontaneous perforation) as compared with EchoG and iv ibuprofen bolus.
{"title":"Ensayo clínico aleatorizado para evaluar dos pautas de administración del ibuprofeno en el tratamiento del ductus arterioso persistente eco-guiado.","authors":"M. Bravo","doi":"10.24217/2530-4984.19V1S1.00012","DOIUrl":"https://doi.org/10.24217/2530-4984.19V1S1.00012","url":null,"abstract":"Patent ductus arteriosus (PDA) is a common condition of preterm infants and it is associated with significant morbidity and mortality. The best therapeutic option for PDA closure remains controversial. Necrotizing enterocolitis (NEC) and bowel spontaneous perforation have been observed in those infants who received pharmacologic treatment of PDA. Conventional treatment of PDA consists on 3 daily doses of intravenous (iv) ibuprofen in bolus 10-5-5 mg/kg/day. Recently, it has been shown that intravenous continuous infusion of ibuprofen (10-5-5 mg/kg/day) seems to be more effective for PDA closure than the conventional treatment with iv bolus. Our group demonstrated in a recent pilot study that the Echocardiographically guided treatment, EchoG, of PDA when it is compared with the conventional treatment, is feasible and reduces the number of ibuprofen doses. Thus, EchoG treatment potentially reduces the adverse events associated with ibuprofen (i.e lower rate of NEC in the experimental group). This multicenter study will evaluate whether the combination of both experimental \u0000therapies (EchoG and iv continuous infusions) reduces the incidence of bowel adverse events (NEC and bowel spontaneous perforation) as compared with EchoG and iv ibuprofen bolus.","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128875890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-09DOI: 10.24217/2530-4984.17v1s1.00007
A. R. Mariblanca, L. D. García, I. García, J. M. Villatoro, E. R. García, M. Moreno, Alberto M. Borobia Pérez
{"title":"Infección por Parvovirus B19 como imitadora de DRESS.","authors":"A. R. Mariblanca, L. D. García, I. García, J. M. Villatoro, E. R. García, M. Moreno, Alberto M. Borobia Pérez","doi":"10.24217/2530-4984.17v1s1.00007","DOIUrl":"https://doi.org/10.24217/2530-4984.17v1s1.00007","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117251835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-09DOI: 10.24217/2530-4984.17v1s1.00006
A. G. Duarte, A. Zubiaur, A. Q. Cortés, M. Bandini, I. H. Surmann, Ilena Medina Expósito, Alberto M. Borobia Pérez
{"title":"¿DRESS o Pustulosis? Esa es la cuestión.","authors":"A. G. Duarte, A. Zubiaur, A. Q. Cortés, M. Bandini, I. H. Surmann, Ilena Medina Expósito, Alberto M. Borobia Pérez","doi":"10.24217/2530-4984.17v1s1.00006","DOIUrl":"https://doi.org/10.24217/2530-4984.17v1s1.00006","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132594288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-09DOI: 10.24217/2530-4984.17v1s1.00002
M. G. Ruiz, Alberto M. Borobia Pérez
{"title":"Tratamiento oftalmológico agudo del paciente con necrolisis epidérmica tóxica.","authors":"M. G. Ruiz, Alberto M. Borobia Pérez","doi":"10.24217/2530-4984.17v1s1.00002","DOIUrl":"https://doi.org/10.24217/2530-4984.17v1s1.00002","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116265566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-09DOI: 10.24217/2530-4984.17V1S1.00004
A. R. Mariblanca, L. D. García, I. García, E. R. García, Kapil Laxman Nanwani Nanwani, E. Sendagorta, Alberto M. Borobia Pérez
{"title":"Necrólisis epidérmica tóxica causada por Pilexil champú: serenoa serrulata vs hidantoína.","authors":"A. R. Mariblanca, L. D. García, I. García, E. R. García, Kapil Laxman Nanwani Nanwani, E. Sendagorta, Alberto M. Borobia Pérez","doi":"10.24217/2530-4984.17V1S1.00004","DOIUrl":"https://doi.org/10.24217/2530-4984.17V1S1.00004","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121964012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-09DOI: 10.24217/2530-4984.17v1s1.00001
S. Nuñez, N. Conde, A. González, A. Pérez
{"title":"The experience of the patient with epidermal necrolysis (TE) in the Getafe Hospital´s Great Burned Unit (GBU) from their own perspective.","authors":"S. Nuñez, N. Conde, A. González, A. Pérez","doi":"10.24217/2530-4984.17v1s1.00001","DOIUrl":"https://doi.org/10.24217/2530-4984.17v1s1.00001","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121495316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-09DOI: 10.24217/2530-4984.17v1s1.00009
Andreina Marques-Mejias, M. Sánchez-Jareño, Ana Fiandor, Rosario Cabañas, Teresa Bellón, Alberto M. Borobia Pérez
{"title":"Neosensibilización a betalactámicos durante síndrome de DRESS por fenitoína.","authors":"Andreina Marques-Mejias, M. Sánchez-Jareño, Ana Fiandor, Rosario Cabañas, Teresa Bellón, Alberto M. Borobia Pérez","doi":"10.24217/2530-4984.17v1s1.00009","DOIUrl":"https://doi.org/10.24217/2530-4984.17v1s1.00009","url":null,"abstract":"","PeriodicalId":257309,"journal":{"name":"IBJ Clinical Pharmacology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114807717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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