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Prescription of antibiotics among paediatric outpatients at Teaching Hospital-Jaffna 贾夫纳教学医院儿科门诊患者抗生素处方分析
Pub Date : 2019-08-19 DOI: 10.4038/JMJ.V31I1.59
S. N. Thiyahiny, M. G. Sathiadas, R. Surenthirakumaran, S. Layanthini
Aim of the study was to evaluate prescription of antibiotics among paediatric outpatients at Teaching Hospital-Jaffna. It was a cross sectional descriptive study carried out among the paediatric outpatients in July and August 2014. A data extraction form was developed based on WHO data collection forms and was used to collect the data. Nine drug use indicators which include modified core and complementary WHO drug use indicators and indicators developed by the investigators were used to evaluate antibiotic prescription. Descriptive statistics were used for data analysis. Out of 1181 prescriptions of paediatric outpatients, 825 (69.9%) had antibiotics. Average number of antibiotics per prescription was 0.7. Percentage of antibiotics prescribed by generic name, from essential medicine list and for common conditions were 97%, 100% and 91.4% respectively. Percentage of prescriptions with the documentation of reason for prescribing an antibiotic was 97%. Only 3.4% antibiotic prescriptions were complete. Percentage of drug cost spent on antibiotics was 33.2% and average antibiotic cost per encounter was 54.34 Sri Lankan rupees. The most frequently prescribed antibiotic group was penicillins (53.3%). The most common indication for antibiotics was respiratory tract infection (70.3%). Majority of the antibiotics (74%) were prescribed in paediatric dosage form. Good prescribing practice was observed for prescribing in generic name, prescribing the antibiotic from essential medicines list, prescribing for common conditions, documentation of reason for prescribing and prescription of paediatric dosage forms. The completeness of antibiotic prescriptions was poor and needs special attention to improve. The drug use indicators are useful tools to evaluate the antibiotic prescriptions in a setting as well as among different settings.
本研究的目的是评估贾夫纳教学医院儿科门诊患者的抗生素处方情况。这是一项横断面描述性研究,于2014年7月和8月在儿科门诊患者中进行。根据世卫组织数据收集表制定了数据提取表,并用于收集数据。采用经修订的世卫组织核心和补充用药指标以及调查人员自行制定的指标等9项用药指标对抗生素处方进行评价。采用描述性统计进行数据分析。在1181张儿科门诊处方中,抗生素处方825张(69.9%)。每张处方平均使用0.7种抗生素。通用名、基本药物清单和常见病抗生素处方比例分别为97%、100%和91.4%。处方中有抗生素处方原因记录的比例为97%。只有3.4%的抗生素处方是完整的。抗生素占药品费用的33.2%,每次就诊的平均抗生素费用为54.34斯里兰卡卢比。最常用的抗生素是青霉素类(53.3%)。最常见的抗生素指征是呼吸道感染(70.3%)。大多数抗生素(74%)以儿科剂型开处方。良好的处方规范包括:通用名称处方、基本药物清单抗生素处方、常见病症处方、处方理由文件和儿科剂型处方。抗生素处方的完整性较差,需要特别注意改进。药物使用指标是评价某一环境以及不同环境间抗生素处方的有用工具。
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引用次数: 1
Idiopathic Hypereosinophilic syndrome with multiorgan involvement 特发性嗜酸性粒细胞增多综合征伴多器官受累
Pub Date : 2019-08-19 DOI: 10.4038/JMJ.V31I1.65
V. Nivethini, A. Hittarage, U. Dissanayake
Idiopathic hypereosinophilic Syndrome (HES) is a rare disorder, and a diagnosis of exclusion of primary and secondary HES. Symptoms develop insidiously and hyper eosinophilia is often detected incidentally. It involves skin, liver, lung, gastro intestinal system, blood, bone marrow and central nervous system. This case study describes about a patient diagnosed as Idiopathic hypereosinophilic Syndrome with bone marrow, lung and liver involvement, who was treated successfully with steroids.
特发性高嗜酸性粒细胞综合征(HES)是一种罕见的疾病,诊断排除原发性和继发性HES。症状发展不明显,嗜酸性细胞过多常被偶然发现。它涉及皮肤、肝、肺、胃肠系统、血液、骨髓和中枢神经系统。这个案例研究描述了一个被诊断为特发性嗜酸性粒细胞增多综合征的患者,骨髓、肺和肝脏受累,用类固醇治疗成功。
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引用次数: 0
A case report on Bradycardia: a rare manifestation of Saw scaled viper bite 心动过缓1例:锯鳞毒蛇咬伤的罕见表现
Pub Date : 2019-08-19 DOI: 10.4038/JMJ.V31I1.66
K. Varuni, S. Sivansuthan, G. Pratheepan, S. Gajanthan
Saw scaled viper is one of the venomous snakes in Sri Lanka. (1) It has different species worldwide. Bleeding manifestations and mortality are varying among them. There is no reported case on saw scaled bite related death in Sri Lanka. (1) Coagulopathy is the commonest manifestation. Here we are reporting the case report on Bradycardia following saw scaled viper bite for the first time. It has occurred after 72 hours and recovered with isoprenaline.
锯鳞蛇是斯里兰卡的毒蛇之一。(1)它在世界各地有不同的种类。出血的表现和死亡率各不相同。在斯里兰卡没有与锯鳞咬伤有关的死亡报告。凝血功能障碍是最常见的表现。本文首次报道锯鳞毒蛇咬伤后心动过缓的病例报告。72小时后发生,用异丙肾上腺素恢复。
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引用次数: 0
Abdominal cutaneous nerve entrapment syndrome (ACNES) 腹皮神经卡压综合征(ACNES)
Pub Date : 2019-08-19 DOI: 10.4038/JMJ.V31I1.62
M. Thirukumar, H. Thambawita
Abdominal cutaneous nerve entrapment syndrome is caused by entrapment of an intercostal nerve in a fibrous ring in the rectus abdominis muscle and causes neuropathic pain. It remains an overlooked cause of chronic abdominal wall pain. Carnett’s test is useful to make a diagnosis. An injection of local anaesthetic and corticosteroid combination relieves pain and it is both diagnostic and treatment. This review article describes its pathophysiology, clinical diagnosis and its management. The databases Medline, and Google Scholar were searched using the terms chronic abdominal pain in general, surgical and gynaecological practice. Database were merged and duplicates were removed. The aim of the review is to update the knowledge on this topic in day to day clinical practice.
腹皮神经卡压综合征是由腹直肌纤维环中的肋间神经卡压引起的,可引起神经性疼痛。它仍然是慢性腹壁疼痛的一个被忽视的原因。卡耐特试验对诊断很有用。局部麻醉剂和皮质类固醇联合注射可减轻疼痛,它既是诊断又是治疗。现就其病理生理、临床诊断及治疗作一综述。在数据库Medline和Google Scholar中使用术语“一般慢性腹痛”、“外科和妇科实践”进行了搜索。已合并数据库并删除了重复项。回顾的目的是在日常临床实践中更新这一主题的知识。
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引用次数: 2
Rare presentation of Typhus Fever with multiorgan failure and Disseminated Intravascular Coagulation 罕见的斑疹伤寒合并多器官功能衰竭和弥散性血管内凝血
Pub Date : 2019-08-19 DOI: 10.4038/JMJ.V31I1.68
S. Sathiaruban, S. Ghetheswaran
A 46 years old female found to be unconscious at home and brought by neighbours. On admission her GCS was 9. Airway was patent with normal breathing pattern. She tachycardic with low volume pulse and bloodpressure is 60/40mmHg. She was febrile on admission. During resuscitation she received fluid boluses up to 1.5 litres (30ml/kg) .Intravenous noradrenaline was commenced to maintain BP. On examination both lungs breath sounds were equal, vesicular breathing and there were occasional crepitations. There was an eschar on the abdominal wall.
一名46岁的女性被发现昏迷在家中,是邻居送来的。入院时,她的GCS为9。气道通畅,呼吸方式正常。她心动过速,脉搏小,血压60/40mmHg。她入院时发烧。在复苏期间,她接受了1.5升(30ml/kg)的液体注射,开始静脉注射去甲肾上腺素以维持血压。检查时双肺呼吸音相等,泡状呼吸,偶有心悸。腹壁上有一个痂。
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引用次数: 0
Bronchiolitis in children 儿童毛细支气管炎
Pub Date : 2019-08-19 DOI: 10.4038/JMJ.V31I1.61
N. Umasankar
Bronchiolitis is the commonest lower respiratory tract infection in infants needing hospital admission. It is caused by the virus mainly the respiratory syncytial virus. The infants typically present with initial upper respiratory symptoms such as rhinitis, nasal congestion and low grade fever which is followed by tachypnea recessions grunting apnoea and cyanosis in severe cases. Young age group, prematurity congenital heart diseases are the major risk factors for the severe disease. Diagnosis of bronchiolitis is mainly depended on clinical features. Clinical assessment of a child suspected with bronchiolitis should include clinical features to diagnoses the bronchiolitis and to assess the severity of the bronchiolitis. There is no definitive management for bronchiolitis. None of the drugs tried in the management of bronhiolitis have shown their efficacy in reducing the length of hospital stay, severity of the illness or improvement in the outcome. The main stay of management is supportive like minimum handling, supplementary oxygen, and care on fluid and nutrition and ventilator support whenever needed.
毛细支气管炎是需要住院的婴儿最常见的下呼吸道感染。主要由呼吸道合胞病毒引起。婴儿通常表现为最初的上呼吸道症状,如鼻炎、鼻塞和低烧,随后出现呼吸急促衰退、咕噜声呼吸暂停和严重的发绀。年龄小、早产儿是先天性心脏病严重发病的主要危险因素。毛细支气管炎的诊断主要依靠临床表现。对疑似毛细支气管炎患儿的临床评估应包括诊断毛细支气管炎的临床特征和评估毛细支气管炎的严重程度。毛细支气管炎没有明确的治疗方法。没有一种治疗支气管炎的药物在缩短住院时间、减轻病情严重程度或改善预后方面显示出疗效。管理的主要停留是支持性的,如最低限度的处理,补充氧气,液体和营养护理以及必要时的呼吸机支持。
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引用次数: 47
The Jaffna Medical Journal as a forum for undergraduate research 《贾夫纳医学杂志》作为本科生研究的论坛
Pub Date : 2019-08-19 DOI: 10.4038/JMJ.V31I1.63
S. Ketheesan, R. Natkunam, N. Ketheesan
It is unfortunate that over the last 65 years many factors have contributed to the sporadic publication of the Jaffna Medical Journal (JMJ). To sustain publication as a regular periodical, it is important to explore avenues to increase the number of submissions of high-quality manuscripts. One untapped source that could significantly enhance the number of submissions to JMJ are manuscripts arising from research undertaken by undergraduate students. To enable such students to produce high quality manuscripts from the work they carry out, students have to be adequately trained and mentored. We are of the view that if appropriate training is provided for undergraduates it will not only help JMJ in the short-term but also nurture the aspirations of future clinicians and researchers who have an interest in inquiry. Moreover, such an investment in student training and capacity building will ensure the future continuity of the Journal.
不幸的是,在过去的65年里,许多因素导致了《贾夫纳医学杂志》(JMJ)的零星出版。为了维持定期刊物的出版,重要的是探索增加高质量稿件提交数量的途径。一个未开发的来源,可以显著提高提交给JMJ的数量是由本科生进行研究的手稿。为了使这些学生能够从他们所从事的工作中写出高质量的手稿,学生们必须得到充分的培训和指导。我们认为,如果为本科生提供适当的培训,这不仅会在短期内帮助JMJ,而且还会培养对探究感兴趣的未来临床医生和研究人员的抱负。此外,这种对学生培训和能力建设的投资将确保期刊未来的连续性。
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引用次数: 0
Clinical governance 临床治理
Pub Date : 2018-12-31 DOI: 10.4038/jmj.v30i2.16
M. G. Sathiadas
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引用次数: 0
Child with recurrent meningitis: Encephalocele causing anterior cranial fossa defect with CSF rhinorrhoea 复发性脑膜炎患儿:脑膨出引起前颅窝缺损伴脑脊液鼻漏
Pub Date : 2018-12-28 DOI: 10.4038/jmj.v30i2.26
V. Mayoorathy, S. Doluweera
Recurrent meningitis in children is potentially life threatening, causing long term morbidities and psychological trauma to the patient through the repeated hospital admission and multiple invasive investigations. Immune deficiency and bacterial migration along congenital or acquired pathways connecting CSF pathways to external surfaces are the two important aetiologies which should be taken into consideration1. We report a case of a boy who presented with recurrent meningitis due to defect in the anterior cranial fossa ethmoidal air cells.
儿童复发性脑膜炎可能危及生命,通过反复住院和多次侵入性检查,对患者造成长期发病率和心理创伤。免疫缺陷和细菌沿连接脑脊液途径与外表面的先天性或获得性途径迁移是应考虑的两个重要病因1。我们报告一个病例的男孩谁提出复发性脑膜炎由于缺损的前颅窝筛气细胞。
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引用次数: 0
A child with fanconi anaemia 一个范可尼贫血症的孩子
Pub Date : 2018-12-28 DOI: 10.4038/JMJ.V30I2.28
A. Puvana, M. G. Sathiadas
Fanconi anemia (FA) is an inherited bone marrow failure syndrome characterized by pancytopenia, physical abnormalities and predisposition to malignancy. It is due to DNA repair defect results in genomic instability. Diagnosis is done by chromosomal fragility test which is high sensitive and low specific test. In this case report, a nine year old girl was accidentally identified with bicytopenia during febrile illness with reactive bone marrow initially. It was followed by pancytopenia with hypocellular marrow. She was diagnosed as FA with classic physical findings of cafe au lait spots, microcephaly, torticollis, hypocellular bone marrow, positive mitomycin-C stress cytogenetic test and high HbF.
范可尼贫血(FA)是一种遗传性骨髓衰竭综合征,以全血细胞减少、身体异常和易患恶性肿瘤为特征。这是由于DNA修复缺陷导致基因组不稳定。诊断方法为染色体脆性试验,该试验灵敏度高,特异性低。在这个病例报告中,一个九岁的女孩在最初的骨髓反应性发热性疾病中意外地被诊断为双氧体减少症。随后是全血细胞减少伴骨髓细胞减少。她被诊断为FA,典型的物理表现为咖啡斑点,小头畸形,斜颈,骨髓细胞减少,丝裂霉素- c应激细胞遗传学检测阳性,HbF高。
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引用次数: 0
期刊
Jaffna Medical Journal
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