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Orofacial pain Orofacial疼痛
Pub Date : 2020-04-01 DOI: 10.1017/cbo9781316134993.064
S. Graff‐Radford, A. Newman
Orofacial pain involves pain conditions associated with the hard and soft tissues of the head, face, neck, and all the intra-oral structures. The field of orofacial pain encompasses diagnosis and treatment of primary headaches, temporomandibular disorders, neuropathic pain, cervical pain, and myofascial pain. The evaluation and treatment of orofacial pain has evolved into a shared responsibility between the dentist and physician, with considerable overlap, distinguished only by the practitioner’s knowledge and training.
口面部疼痛包括与头部、面部、颈部和所有口腔内结构的软硬组织有关的疼痛状况。口腔面部疼痛的领域包括原发性头痛、颞下颌紊乱、神经性疼痛、颈椎疼痛和肌筋膜疼痛的诊断和治疗。口腔面部疼痛的评估和治疗已经演变为牙医和医生之间的共同责任,有相当大的重叠,只有从业者的知识和培训才能区分。
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引用次数: 0
Tension-type headache 紧张型头痛
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0029
S. Evers
Tension-type headache (TTH) is usually a dull, bilateral headache without accompanying symptoms. It is divided into three subtypes: infrequent episodic TTH (< 1 headache day per month), frequent episodic TTH (1–14 headache days per month), and chronic TTH (≥ 15 headache days per month). This division is highly relevant for three reasons. Firstly, impact on quality of life differs considerably between the three subtypes. Secondly, the pathophysiological mechanisms also differ. Peripheral mechanisms such as muscle tension are more important in episodic TTH, whereas central pain sensitization with reduced antinociceptive mechanisms are pivotal in chronic TTH. Thirdly, treatment differs between the subtypes, with symptomatic and prophylactic treatment being more appropriate for episodic and chronic TTH, respectively. Non-pharmacological management should always be part of the treatment. Patients with episodic TTH are treated with analgesics, while prophylactic drugs (in particular antidepressants) should be considered in patients with very frequent episodic or chronic TTH.
紧张性头痛(TTH)通常是一种无伴随症状的钝性双侧头痛。它分为三种亚型:不频繁发作性TTH(每月头痛天数< 1天)、频繁发作性TTH(每月头痛天数1 - 14天)和慢性TTH(每月头痛天数≥15天)。这一划分具有高度相关性,原因有三。首先,对生活质量的影响在三种亚型之间有很大差异。其次,其病理生理机制也存在差异。肌张力等外周机制在发作性TTH中更为重要,而中枢疼痛敏化与抗感觉机制降低在慢性TTH中至关重要。第三,不同亚型的治疗方法不同,对症治疗和预防治疗分别更适合于发作性和慢性TTH。非药物治疗应始终是治疗的一部分。发作性TTH患者使用止痛药治疗,而对于非常频繁的发作性或慢性TTH患者应考虑使用预防性药物(特别是抗抑郁药)。
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引用次数: 0
Headache and sleep 头痛与睡眠
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0057
S. Evers, R. Jensen
Headache and sleep share some clinical and physiological features. In ancient times good sleep was regarded as a cure for headache. The neuroanatomical links between the two conditions is the hypothalamus and one of the physiological links is the orexin metabolism. In the clinical setting, there are headache disorders predominantly occurring during sleep, such as cluster headache, or often occur in the early morning, such as migraine attacks. On the other side, sleep disorders can trigger headache such as sleep apnoea syndrome or bruxism. Recently, a significant association has been described between migraine and restless legs syndrome. Drugs used in headache and migraine treatment can lead to sleep disturbances such as vivid dreams caused by betablockers or hypersomnia caused by tricyclic antidepressants. A specific condition is hypnic headache, which exclusively occurs during the sleep.
头痛和睡眠有一些共同的临床和生理特征。在古代,良好的睡眠被认为是治疗头痛的一种方法。这两种情况之间的神经解剖学联系是下丘脑,生理联系之一是食欲素代谢。在临床环境中,头痛疾病主要发生在睡眠期间,如丛集性头痛,或经常发生在清晨,如偏头痛发作。另一方面,睡眠障碍会引发头痛,如睡眠呼吸暂停综合征或磨牙症。最近,偏头痛和不宁腿综合症之间有明显的联系。用于治疗头痛和偏头痛的药物可导致睡眠障碍,如β受体阻滞剂引起的生动梦境或三环抗抑郁药引起的嗜睡。一种特殊的情况是睡眠性头痛,它只发生在睡眠中。
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引用次数: 0
Thunderclap headache 雷声头痛
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0034
H. Koppen, A. van Sonderen, S. F. de Bruijn
Severe headache of sudden onset is relatively common, especially in emergency departments, and has an extensive differential. Neurovascular disorders often present with thunderclap headache. Although the initial work-up is focused to exclude subarachnoid haemorrhage, several other serious life-threatening disorders must be considered, such as cerebral venous sinus thrombosis and stroke. Furthermore, other causes like reversible cerebral vasoconstriction syndrome are recognized more and more. In this chapter the work-up of alert, neurologically intact patients presenting with an acute and severe headache, not related to trauma, will be described.
突然发作的严重头痛是相对常见的,特别是在急诊科,并有广泛的差异。神经血管疾病常表现为雷击性头痛。虽然最初的检查重点是排除蛛网膜下腔出血,但必须考虑其他一些严重的危及生命的疾病,如脑静脉窦血栓形成和中风。此外,其他原因如可逆性脑血管收缩综合征也越来越被认识到。在这一章的工作,警觉,神经完整的病人呈现急性和严重的头痛,不相关的创伤,将被描述。
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引用次数: 0
Headaches in the elderly 老年人头痛
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0051
Jonathan H. Smith, Andreas Straube, Jerry W. Swanson
There is a non-controversial definition about who is an elderly patient. The age group above 85 years is the fastest growing segment in the total population. Persisting pain is not rare in this patient group and the prevalence for persisting pain is 40–79%. Migraine prevalence declines gradually after the age of 40 years, but even in the age group of 60 years and older up to 5% complain of migraine and in some patients the symptoms change towards more tension type-like headaches. Tension-type headaches are thought to be the most prevalent primary headaches in the elderly, with a 1-year prevalence of about 36%; secondary headaches often present as tension type-like headaches. A typical age-bounded headache is hypnic headache, which is only seen in patients older than 55 years of age. In the treatment of headaches in the elderly, the pharmacokinetic changes with age should be considered; the distribution volume and elimination kinetics are different in the elderly. Therefore, treatment should be initiated as ‘slow and low’.
对于谁是老年病人,有一个没有争议的定义。85岁以上的年龄组是总人口中增长最快的部分。持续疼痛在该患者组中并不罕见,持续疼痛的患病率为40-79%。偏头痛的患病率在40岁以后逐渐下降,但即使在60岁及以上的年龄组中,也有5%的人抱怨偏头痛,有些患者的症状转变为更多的紧张性头痛。紧张性头痛被认为是老年人中最常见的原发性头痛,1年患病率约为36%;继发性头痛通常表现为紧张性头痛。典型的年龄限制头痛是睡眠性头痛,仅见于55岁以上的患者。在治疗老年人头痛时,应考虑药代动力学随年龄的变化;老年人的分布、体积和消除动力学不同。因此,治疗应以“缓慢和低剂量”开始。
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引用次数: 0
Cervicogenic headache 颈源性头痛
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0036
Nikolai Bogduk
Idiopathic intracranial hypertension (IIH) is a disorder of raised intracranial pressure, almost always associated with papilloedema, in the absence of underlying central nervous system pathology. It is a rare disease, with an annual incidence of around 1 in 100,000 persons, with an age of onset between 11 and 58 years. It is predominantly seen in obese women of childbearing age (incidence 10–20 per 100,000), but can affect any age, ethnicity, or sex. The two morbidities associated with IIH are vision loss and headache, with headache ultimately affecting > 90% of patients. The exact mechanisms underlying IIH related headache pain are still unknown, but it is often debilitating and significantly impacts on quality of life. The goal of treatment is to reduce intracranial pressure to minimize vision loss and headaches. Effective medical and surgical interventions are available for treatment of headache in IIH and are tailored to each individual patient. Overall, the prognosis for treatment of headache in IIH is good.
特发性颅内高压症(IIH)是一种颅内压升高的疾病,几乎总是伴有乳头水肿,但没有潜在的中枢神经系统病变。这是一种罕见疾病,年发病率约为十万分之一,发病年龄在 11 岁至 58 岁之间。它主要见于育龄期肥胖妇女(发病率为十万分之 10-20),但任何年龄、种族或性别的人都可能患病。与 IIH 相关的两种病症是视力下降和头痛,其中头痛最终影响到 90% 以上的患者。与 IIH 相关的头痛的确切机制尚不清楚,但它通常会使人衰弱,严重影响生活质量。治疗的目标是降低颅内压,以尽量减少视力丧失和头痛。目前已有治疗 IIH 头痛的有效药物和手术干预措施,并可根据每位患者的具体情况进行调整。总体而言,治疗 IIH 头痛的预后良好。
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引用次数: 0
Treatment and management 治疗和管理
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0016
D. Magis
A significant proportion of migraine patients appears reluctant to take migraine preventive drugs, or do not sufficiently improve when on available medications. The concept of non-pharmacological migraine approaches includes a large diversity of treatments: oral therapies (nutraceuticals or herbal medicines); exercise, behavioural therapies, and multidisciplinary care; acupuncture; peripheral invasive or non-invasive nerve stimulation; and, finally, brain neuromodulation (transcranial magnetic stimulation and transcranial direct current stimulation). The majority of these treatments have few adverse events and their efficacy often seems within the range of usual migraine preventive drugs. However, large placebo-controlled studies are often lacking. Thus, keeping these alternatives in mind when taking care of migraine patients in daily clinical practice is worthwhile.
相当大比例的偏头痛患者似乎不愿意服用偏头痛预防药物,或者在使用现有药物后症状没有得到充分改善。非药物偏头痛治疗方法的概念包括多种治疗方法:口服治疗(营养品或草药);运动、行为疗法和多学科护理;针灸;外周侵入性或非侵入性神经刺激;最后是脑神经调节(经颅磁刺激和经颅直流电刺激)。大多数这些治疗几乎没有不良事件,其疗效似乎通常在常规偏头痛预防药物的范围内。然而,通常缺乏大规模的安慰剂对照研究。因此,在日常临床实践中照顾偏头痛患者时,记住这些选择是值得的。
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引用次数: 0
Migraine and vertigo 偏头痛和眩晕
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0013
Y. Cha
The phenomena of migraine headache and vertigo share many epidemiological, anatomical, and clinical characteristics. The historically parallel development of the neuroscience of each field has formally intersected in the development of consensus criteria for vestibular migraine and the inclusion of vestibular migraine in the International Classification of Headache Disorders. Differences exist in the temporal profile of head pain and vertigo as manifestations of migraine, which can obscure the association. However, the growing body of evidence on the common demographic, neurochemical signature, and treatment responses of pain and vestibular symptoms indicate that they exist as symptoms of a common syndrome, one which can only be fully understood by recognizing the significance of each kind of manifestation.
偏头痛和眩晕的现象具有许多流行病学、解剖学和临床特征。历史上每个领域神经科学的平行发展已经在前庭偏头痛的共识标准的发展和前庭偏头痛纳入国际头痛疾病分类中正式相交。偏头痛表现为头痛和眩晕的时间分布存在差异,这可能会模糊两者之间的联系。然而,越来越多的证据表明,疼痛和前庭症状的共同人口学特征、神经化学特征和治疗反应表明,它们是一种共同综合征的症状,只有认识到每种表现的重要性,才能充分理解这种症状。
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引用次数: 0
Hemicrania continua 头痛还
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0021
Johan Lim, Joost Haan
Hemicrania continua is an uncommon primary headache characterized by continuous, unilateral cranial pain of moderate intensity, more painful exacerbations with cranial autonomic features, and an absolute response to indomethacin. It is considered one of the trigeminal autonomic cephalalgias. Activation of the trigeminal–autonomic reflex and the contralateral posterior hypothalamic grey is thought to play an important role in its pathophysiology. The mean age of onset is in the third decade and there is a female preponderance of 2:1. Hemicrania continua can be divided into a remitting and an unremitting type; most patients suffer from the unremitting type. Any part of the head or neck can be affected, and pain is mainly described as throbbing. Many patients experience migrainous features during exacerbations. Physical and supplementary investigations are mostly normal. Other trigeminal autonomic cephalalgias and migraine are the main differential diagnostic alternatives for consideration.
持续性偏头痛是一种罕见的原发性头痛,其特征是持续的、中等强度的单侧头部疼痛,伴有颅自主神经特征的疼痛加重,对吲哚美辛有绝对反应。它被认为是三叉神经自主神经性头痛之一。三叉神经自主反射和对侧下丘脑后灰的激活被认为在其病理生理中起重要作用。平均发病年龄为30岁,女性发病率为2:1。持续型偏头痛可分为缓解型和持续型;大多数患者患有不懈型。头部或颈部的任何部位都可能受到影响,疼痛主要表现为悸动。许多患者在病情加重时出现偏头痛特征。物理和辅助检查大多正常。其他三叉神经自主神经性头痛和偏头痛是主要的鉴别诊断选择。
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引用次数: 0
Paroxysmal hemicrania
Pub Date : 2020-04-01 DOI: 10.1093/med/9780198724322.003.0019
G. Bussone, E. Cittadini
Paroxysmal hemicrania is classified as a trigeminal autonomic cephalalgia by the International Classification of Headache Disorders, third edition. The current criteria require at least 20 attacks of severe unilateral orbital, supraorbital, or temporal pain, lasting 2–30 minutes, accompanied by ipsilateral cranial autonomic features such as ptosis, eyelid oedema, conjunctival injection, lacrimation, nasal blockage, or rhinorrhoea. Attacks usually have a frequency of more than five per day, and respond exquisitely to indomethacin.
阵发性偏头痛被归类为三叉神经性自主脑痛的国际头痛疾病分类,第三版。目前的标准要求至少20次严重的单侧眼眶、眶上或颞部疼痛,持续2-30分钟,伴有同侧颅自主神经特征,如上睑下垂、眼睑水肿、结膜注射、流泪、鼻阻塞或鼻漏。发作频率通常在每天5次以上,并且对吲哚美辛反应灵敏。
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引用次数: 0
期刊
Oxford Textbook of Headache Syndromes
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