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Risk Factors of Relapse After Successful Electroconvulsive Therapy for Taiwanese Patients With Major Depression 台湾重性抑郁症患者成功电休克治疗后复发的危险因素
Pub Date : 2019-07-24 DOI: 10.1097/YCT.0000000000000619
Wei-Cheng Yang, Ching-Hua Lin, Cheng-Chung Chen
Objectives Major depressive disorder is a recurrent illness. Treatment strategies are generally focused on achieving remission and preventing relapse/recurrence. The aim of this study was to explore the risk factors associated with relapse for remitted patients during the 12-week follow-up. Methods This was an open-label trial for major depressive disorder patients receiving acute treatments with electroconvulsive therapy (ECT) and continuation medication in the 12-week follow-up. Symptom severity and psychosocial functioning were assessed using the 17-item Hamilton Rating Scale for Depression (HAMD-17) and the Work and Social Adjustment Scale at each visit. Remission was defined as a HAMD-17 of 7 or less after acute treatment. Relapse was defined as a HAMD-17 of 14 or greater. Subjects achieving remission after acute treatments were included for analysis. Survival analysis was used to investigate the factors associated with relapse. Results Sixty patients receiving ECT for acute treatment were enrolled for 12-week follow-up. Using Cox regression analysis, a greater number of previous major depressive episodes and greater baseline Work and Social Adjustment Scale scores were significantly associated with shorter time to relapse. Conclusions The goal of acute treatment should focus on functional remission to prevent relapse. Further studies related to more effective treatments to prevent relapse after acute ECT are required in the future.
目的重度抑郁症是一种复发性疾病。治疗策略通常侧重于实现缓解和防止复发/复发。本研究的目的是在12周的随访中探讨与缓解患者复发相关的危险因素。方法本研究是一项开放标签试验,在12周的随访中,接受电休克治疗(ECT)和持续药物治疗的重度抑郁症患者。在每次访问时,使用17项汉密尔顿抑郁评定量表(HAMD-17)和工作与社会适应量表对症状严重程度和心理社会功能进行评估。缓解被定义为急性治疗后HAMD-17为7或更低。复发的定义是HAMD-17评分为14或更高。急性治疗后达到缓解的受试者被纳入分析。生存率分析用于研究复发的相关因素。结果60例接受电痉挛治疗的急性期患者入选,随访12周。使用Cox回归分析,既往重度抑郁发作次数越多,基线工作和社会适应量表得分越高,复发时间越短。结论急性期治疗应以功能缓解为主,防止复发。未来需要进一步研究更有效的治疗方法来预防急性ECT后复发。
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引用次数: 3
Handbook of ECT: A Guide to Electroconvulsive Therapy for Practitioners 电痉挛治疗手册:从业人员电痉挛治疗指南
Pub Date : 2019-06-01 DOI: 10.1097/YCT.0000000000000591
W. McCall
Copyright © aimed at both practitioners and trainees who need a quick, up-to-date source about most aspects of clinical ECT. It is not meant to be an exhaustive text, rather a primer of technique.” In my reading of this book, I found that I agreed with Dr Kellner's assessment and directions on each aspect of the practice of ECT. The clinical directions provided in this book will place the reader squarely in the mainstream of ECT practice. Although the book intentionally avoids digressions into areas that lack consensus, ample references are provided for the reader whowants to delve more deeply into the science. Useful tables and figures are spaced throughout, and a comprehensive index helps readers quickly find specific topics. Blank pages at the end allow the reader to make their own notes as they go.
版权所有©针对需要关于临床ECT大多数方面的快速,最新来源的从业人员和培训生。它不是一个详尽的文本,而是一个技术入门。”在我阅读这本书的过程中,我发现我同意凯尔纳医生对电休克疗法实践的每个方面的评估和指导。在这本书中提供的临床指导将把读者放在电痉挛疗法的主流实践中。虽然这本书有意避免离题到缺乏共识的领域,但为想要更深入地研究科学的读者提供了充足的参考资料。有用的表格和数字是间隔的,一个全面的索引帮助读者快速找到具体的主题。最后的空白页允许读者在阅读过程中做自己的笔记。
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引用次数: 8
Patient- and Family-Centered Electroconvulsive Therapy. 以病人和家庭为中心的电休克疗法。
IF 2.5 Pub Date : 2019-06-01 DOI: 10.1097/YCT.0000000000000596
Herbert A Fox

This article builds upon prior efforts to improve the quality of electroconvulsive therapy (ECT) practice and care by encouraging the participation of family members in the ECT process. This participation included the presence of a family member or significant other (SO) in the treatment room during the ECT procedure. Suggestions for limiting that presence to the induction process and for providing limited physical contact with the patient are proposed. The participation of the SO during the pretreatment assessment process is encouraged. Because of possible impairment of memory and judgment, accurate information about the patient's condition and intercurrent life events, as provided by the SO, is often crucial. Furthermore, the patient's report may be influenced by the common experience of fear of ECT. Under these circumstances, an alliance with the SO may at times be more crucial than the alliance with the patient. The importance of establishing a therapeutic alliance with both patient and SO is emphasized. An illustrative clinical vignette is provided.

本文建立在以前的努力,以提高质量的电休克治疗(ECT)的实践和护理,鼓励家庭成员参与电休克治疗过程。这种参与包括在电痉挛治疗过程中有家庭成员或重要的其他人(SO)在治疗室。建议将其限制在诱导过程中,并建议与患者进行有限的身体接触。鼓励社会服务人员参与预处理评估过程。由于记忆和判断可能受损,SO提供的有关患者病情和生活事件的准确信息往往至关重要。此外,患者的报告可能会受到对电痉挛疗法的普遍恐惧经验的影响。在这种情况下,与SO的合作有时可能比与患者的合作更为重要。强调了与患者和SO建立治疗联盟的重要性。提供了一个说明性的临床小插图。
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引用次数: 1
The FDA Final Order on ECT Devices, Finally. FDA关于电痉挛装置的最终指令,终于。
IF 2.5 Pub Date : 2019-06-01 DOI: 10.1097/YCT.0000000000000601
Charles H Kellner, William V McCall, Harm-Pieter Spaans, Pascal Sienaert
n December 26, 2018, FDA published its final order on the reclassification of ECT devices. CulO minating a process that got underway in 2011 with the convening of the Neurological Devices Classification panel, the final order is welcome news for ECT patients, their families, and for ECT practitioners. While much of the reclassification process is bureaucratically complex, the end result is simple and clear: the practice of ECTwill continue unimpeded in the United States.
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引用次数: 6
Developing and Implementing a Quality Assurance Strategy for Electroconvulsive Therapy. 电休克治疗质量保证策略的制定与实施。
IF 2.5 Pub Date : 2019-03-01 DOI: 10.1097/YCT.0000000000000497
Jessa Hollingsworth, Beverly Baliko, Selina McKinney, Peter Rosenquist

Background: The literature provides scant guidance in effective quality assurance strategies concerning the use of electroconvulsive therapy (ECT) for the treatment of psychiatric conditions. Numerous guidelines are published that provide guidance in the delivery of care; however, little has been done to determine how a program or facility might ensure compliance to best practice for safety, tolerability, and efficacy in performing ECT.

Objective: The objective of this project was to create a quality assurance strategy specific to ECT. Determining standards for quality care and clarifying facility policy were key outcomes in establishing an effective quality assurance strategy.

Methods: An audit tool was developed utilizing quality criteria derived from a systematic review of ECT practice guidelines, peer review, and facility policy. All ECT procedures occurring over a 2-month period of May to June 2017 were retrospectively audited and compared against target compliance rates set for the facility's ECT program. Facility policy was adapted to reflect quality standards, and audit findings were used to inform possible practice change initiatives, were used to create benchmarks for continuous quality monitoring, and were integrated into regular hospital quality meetings.

Results: Clarification on standards of care and the use of clinical auditing in ECT was an effective starting point in the development of a quality assurance strategy. Audit findings were successfully integrated into the hospital's overall quality program, and recognition of practice compliance informed areas for future quality development and policy revision in this small community-based hospital in the southeastern United States.

Conclusions: This project sets the foundation for a quality assurance strategy that can be used to help monitor procedural safety and guide future improvement efforts in delivering ECT. Although it is just the first step in creating meaningful quality improvement, setting clear standards and identifying areas of greatest clinical need were crucial beginning for this hospital's growing program.

背景:关于使用电休克疗法(ECT)治疗精神疾病的有效质量保证策略,文献提供的指导很少。出版了许多指南,为提供护理提供指导;然而,在确定一个项目或机构如何确保实施ECT的安全性、耐受性和有效性方面符合最佳实践方面,却做得很少。目的:这个项目的目的是建立一个特定于ECT的质量保证策略。确定质量护理标准和澄清设施政策是建立有效质量保证战略的关键成果。方法:利用从电痉挛疗法实践指南、同行评议和设施政策的系统审查中得出的质量标准,开发了一种审计工具。2017年5月至6月2个月期间发生的所有ECT手术都进行了回顾性审计,并与该设施ECT项目设定的目标合规率进行了比较。对设施政策进行了调整,以反映质量标准,审计结果用于通知可能的做法改变举措,用于创建持续质量监测的基准,并纳入定期的医院质量会议。结果:明确电痉挛治疗的护理标准和临床审计的使用是制定质量保证策略的有效起点。审核结果被成功地整合到医院的整体质量计划中,对实践合规的认可为这家美国东南部的小型社区医院未来的质量发展和政策修订提供了信息。结论:该项目为质量保证策略奠定了基础,该策略可用于帮助监测手术安全性,并指导未来电痉挛治疗的改进工作。虽然这只是创造有意义的质量改进的第一步,但制定明确的标准和确定最大的临床需求领域是该医院不断发展的项目的关键开端。
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引用次数: 1
The Madness of Fear—A History of Catatonia 恐惧的疯狂——紧张症的历史
Pub Date : 2018-12-01 DOI: 10.1097/YCT.0000000000000532
P. Sienaert
“T oday (...) catatonia is edging its way back to center stage as an independent disorder,” Shorter and Fink state in their new book on the history of this startling syndrome. Thanks, not least, to the authors' relentless effort. Edward Shorter is professor of the history of medicine at the University of Toronto. Max Fink, professor of psychiatry and neurology, emeritus, worked at Stony Brook School of Medicine, New York. The former has written extensively about the history of electroconvulsive therapy (ECT); the latter, Fink, is the history of ECT. One expects to read a history book. But The Madness of Fear is so much more than that. Some phrases are so literary that one cannot resist the temptation to read them aloud repetitively making one's family members frown. Here is one: “Buffeted by psychoanalysis and blinded by the prestige of German learning, clinicians let catatonia languish in the quagmire of schizophrenia” (p117). The authors “join other scholars in the growing disbelief about ‘schizophrenia’” (p120). Throughout the book, they don't pass up a chance to criticize the concept of schizophrenia that, according to Meduna, already in 1946, “doesn't mean anything more than ‘crazy’ or ‘cracked’” (p78). Not only do the authors unfold the history of catatonia, from Kahlbaum's predecessors in the early 19th century (chapter 2, “Catatonia Before Kahlbaum”) up to the so-called “resignation syndrome”marked by stupor among refugee children coming to Sweden, first described not more than 2 years ago. They also offer the reader a clinical lesson. Fink and Shorter want the reader to recognize the clinical picture of catatonia, to detect a severe condition that is fairly easy to cure. In an erawhere it is “bon ton” to hail dimensional diagnoses and demonize categorical labeling, Fink states it is our job as medical doctors to label our patients, provided that the label specifies an identifiable syndrome and brings a successful treatment (Fink, personal communication, May 6, 2018). A myriad of case descriptions with a sense of phenomenological detail that has
肖特和芬克在他们关于这种惊人综合症历史的新书中写道:“今天,紧张症作为一种独立的疾病正在慢慢回到舞台的中心。”尤其要感谢作者们不懈的努力。爱德华·肖特(Edward Shorter)是多伦多大学医学史教授。马克斯·芬克,精神病学和神经学名誉教授,曾在纽约石溪医学院工作。前者撰写了大量关于电休克疗法(ECT)的历史;后者,芬克,是电痉挛疗法的历史。人们期望读一本历史书。但《恐惧的疯狂》远不止于此。有些短语是如此的文学,以至于一个人无法抗拒大声朗读它们的诱惑,反复地让家人皱眉。这里有一个:“受到精神分析的打击,被德国学术的声望蒙蔽了眼睛,临床医生让紧张症在精神分裂症的泥潭中憔悴”(p117)。两位作者“加入了其他越来越不相信‘精神分裂症’的学者行列”(p120)。在整本书中,他们没有放过任何一个批评精神分裂症概念的机会,根据梅杜纳在1946年的说法,“精神分裂症的意思只不过是‘疯狂’或‘崩溃’”(p78)。作者不仅揭示了紧张症的历史,从19世纪初卡尔鲍姆的前辈(第二章,“卡尔鲍姆之前的紧张症”)到所谓的“辞职综合症”,以来到瑞典的难民儿童的麻木为标志,不到两年前首次被描述。他们也给读者上了一堂临床课。芬克和肖特希望读者认识到紧张症的临床症状,发现一种相当容易治愈的严重疾病。芬克说,在一个推崇维度诊断和妖魔化分类标签的地方,给病人贴上标签是医生的工作,前提是这个标签指定了一种可识别的综合征,并带来了成功的治疗(芬克,《个人沟通》,2018年5月6日)。无数的案例描述带有现象学的细节感
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引用次数: 45
International Society for ECT and Neurostimulation Annual Meeting Abstracts 2018 国际电痉挛和神经刺激学会2018年年会摘要
Pub Date : 2018-09-01 DOI: 10.1097/yct.0000000000000520
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引用次数: 0
Intramuscular Ketamine Protocol as an Alternative to Physical Restraints for Electroconvulsive Therapy Administration in a Psychotic Patient 肌注氯胺酮方案作为精神病人电休克治疗中物理约束的替代方案
Pub Date : 2018-07-01 DOI: 10.1097/00124509-900000000-99220
L. Smith-Martinez, L. Chatham, Purushothaman Muthukanagaraj
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引用次数: 0
Re: "See Many, Do None, Now We Need Your Help". 回复:“多看,不做,现在我们需要你的帮助”。
IF 2.5 Pub Date : 2018-06-01 DOI: 10.1097/YCT.0000000000000496
Jorge Mota
different ECT-related anxiety trajectories. In some patients, anxiety levels increase during a treatment course, whereas in others, it decreases or remains unchanged. As we already stated in our review, patients are not simply anxious or not anxious but experience anxiety on a broad continuum, depending on a variety of thoughts and experiences, weighing risks and benefits of the treatment during different stages of it. Interestingly, Swartz states that ECT can also protect against developing PTSD. He argues that the threatening experiences of a severe psychiatric illness such as melancholia or acute psychosis itself can generate anxiety, such as PTSD. Electroconvulsive therapy might be able to prevent PTSD by decreasing patients' exposure to melancholic, psychotic, or suicidal thoughts. In a recent book about the cultural history of ECT yet another explanation is given to the question of why some patients experience such high levels of anxiety. Sadowsky argues convincingly that people's fear of ECT derives not simply from prejudice but from a social memory of uses that are fearsome. Although its efficacy is beyond doubt, ECT has a troubled history and has been misused.Most likely, the misuses of ECT in the past as well as the persistent negative portrayal in movies and television programs can also help to understand some patients' fear of ECT. It seems that the history of ECT itself has created some kind of collective, archetypal PTSD. Ironically, in its hay days, ECTwas seen as a treatment that got rid of the intense fears patients experienced with pharmacoconvulsive therapy, and practitioners were struck by the reduction in fear and resistance from patients treated with ECT. Both our review and Dr Fox's commentary stress the virtual absence of scientific data and the need for further prospective studies. Only a better understanding of the mechanisms involved in ECT-related anxiety will facilitate designing adequate anxietyreducing or -preventing interventions to improve the well-being of severely ill patients in need of ECT.
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引用次数: 0
Successful Treatment With Electroconvulsive Therapy of a Patient With Chiari Malformation Type I 电休克疗法成功治疗1例I型基亚里畸形
Pub Date : 2018-06-01 DOI: 10.1097/00124509-900000000-99227
Dimitry Francois, Tiffany Huang
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引用次数: 0
期刊
The Journal of ECT
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