T. Vislohuzova, N. Galatenko, R. Rozhnova, V. Bogatyrov, M. Galaburda
A series of polymeric composites based on polyurethanes with copolymer fragments of poly(vinyl butyral-vinyl acetate-vinyl alcohol) and 1,6-hexamethylenediamine filled with modified precipitated silica were synthesized. The content of silver in the nanocomposites was 0.1–0.2 and of copper – 0.14 and 0.2 mmol per 1 g of SiO2 (02AgCu; AgCu and 01Ag samples). The content of silver-containing silica filler in the polymer composites was 0.1, 0.5 and 1.0 wt. %. By means of the IR spectroscopy, it has been found that a physical immobilization of modified silica in the polymeric matrix takes place due to the presence of intermolecular hydrogen bonds. The influence of fillers on the structure and properties of polymer materials, in particular, on thermophysical properties and physico-mechanical parameters (tensile strength and relative elongation at rupture), were investigated. The results of physico-mechanical tests indicate that the strength characteristics of polyurethane depend on the content and concentration of fillers. It has been found that the polymeric sample filled with 02AgCu nanocomposite (0.2 mmol of Ag and Cu per 1 g of SiO2) has the highest strength of the rupture. It has been shown that the introduction of modified silica leads to a reduction of relative elongation at rupture of polymeric nanocomposite. The highest values showed the sample filled with AgCu (0.1 and 0.12 mmol Ag and Cu, respectively, per 1 g of SiO2). The introduction of silver-containing silica nanocomposites into a polyurethane, containing polyvinylbutiral copolymer fragments, leads to an increase in tensile strength and reduction of relative elongation at rupture. Polymeric composite with 0.5 wt. % of filler had the highest values of physico-mechanical parameters. It has been shown that the thermosphysical characteristics depend on the concentration and composition of the fillers and have a nonlinear character. The synthesized nanocomposites can be effectively used as biomedical materials.
{"title":"Composite materials based on polyurethane with fragments of poly(vinyl butyral-vinyl acetate-vinyl alcohol) copolymer in their structure filled with silver- and copper-containing silica","authors":"T. Vislohuzova, N. Galatenko, R. Rozhnova, V. Bogatyrov, M. Galaburda","doi":"10.15407/hftp13.03.274","DOIUrl":"https://doi.org/10.15407/hftp13.03.274","url":null,"abstract":"A series of polymeric composites based on polyurethanes with copolymer fragments of poly(vinyl butyral-vinyl acetate-vinyl alcohol) and 1,6-hexamethylenediamine filled with modified precipitated silica were synthesized. The content of silver in the nanocomposites was 0.1–0.2 and of copper – 0.14 and 0.2 mmol per 1 g of SiO2 (02AgCu; AgCu and 01Ag samples). The content of silver-containing silica filler in the polymer composites was 0.1, 0.5 and 1.0 wt. %. By means of the IR spectroscopy, it has been found that a physical immobilization of modified silica in the polymeric matrix takes place due to the presence of intermolecular hydrogen bonds. The influence of fillers on the structure and properties of polymer materials, in particular, on thermophysical properties and physico-mechanical parameters (tensile strength and relative elongation at rupture), were investigated. The results of physico-mechanical tests indicate that the strength characteristics of polyurethane depend on the content and concentration of fillers. It has been found that the polymeric sample filled with 02AgCu nanocomposite (0.2 mmol of Ag and Cu per 1 g of SiO2) has the highest strength of the rupture. It has been shown that the introduction of modified silica leads to a reduction of relative elongation at rupture of polymeric nanocomposite. The highest values showed the sample filled with AgCu (0.1 and 0.12 mmol Ag and Cu, respectively, per 1 g of SiO2). The introduction of silver-containing silica nanocomposites into a polyurethane, containing polyvinylbutiral copolymer fragments, leads to an increase in tensile strength and reduction of relative elongation at rupture. Polymeric composite with 0.5 wt. % of filler had the highest values of physico-mechanical parameters. It has been shown that the thermosphysical characteristics depend on the concentration and composition of the fillers and have a nonlinear character. The synthesized nanocomposites can be effectively used as biomedical materials.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123538328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Curcumin, a sparingly soluble polyphenol of plant origin, has antitumor, anti-inflammatory, antithrombotic, antidiabetic and antimicrobial properties. Currently, an important task is the development of medicinal composites based on curcumin, which provide an increase in its solubility and, accordingly, bioavailability. The aim of the work is to determine the optimal conditions for the adsorption of curcumin on the surface of a silica enterosorbent as soluble supramolecular complexes with a cationic dimeric surfactant decamethoxine. The UV/Vis spectroscopy data indicate that supramolecular interactions with decamethoxine lead to changes in the spectral characteristics of curcumin in solutions and on silica surface. The bathochromic shift of the absorption spectrum of curcumin in decamethoxine solutions characterizes the polarization of its carbonyl group in supramolecular complexes. The hypsochromic shift in the absorption spectra of curcumin adsorbed from decamethoxine solutions on silica is explained by the violation of its conjugated π-bond system, resulted probably from the change in the spatial orientation of the curcumin molecule at the adsorption of its complexes on the sorbent surface. Curcumin is adsorbed on highly dispersed silica much more effectively from decamethoxine solutions than from aqueous solutions. The adsorption of curcumin is maximal (92 %) at a concentration of decamethoxine 0.002 M, and decreases sharply to 9 % in the micellar region of concentrations (≥ 0.008 M). The dependence of curcumin adsorption on decamethoxine concentration is described by a domed curve, which indicates a significant contribution of hydrophobic interactions to the formation of supramolecular complexes of curcumin with cationic surfactant and their adsorption on silica surface. The results obtained are of practical importance and can be used in the development of new, more effective medicines containing bioactive curcumin, antiseptic decamethoxine and silica enterosorbent.
{"title":"Effect of supromolecular interactions with cationic surfactant decamethoxine on adsorption of curcumine on highly dispersed silica","authors":"N. Lipkovska, V. Barvinchenko","doi":"10.15407/hftp13.03.311","DOIUrl":"https://doi.org/10.15407/hftp13.03.311","url":null,"abstract":"Curcumin, a sparingly soluble polyphenol of plant origin, has antitumor, anti-inflammatory, antithrombotic, antidiabetic and antimicrobial properties. Currently, an important task is the development of medicinal composites based on curcumin, which provide an increase in its solubility and, accordingly, bioavailability. The aim of the work is to determine the optimal conditions for the adsorption of curcumin on the surface of a silica enterosorbent as soluble supramolecular complexes with a cationic dimeric surfactant decamethoxine. The UV/Vis spectroscopy data indicate that supramolecular interactions with decamethoxine lead to changes in the spectral characteristics of curcumin in solutions and on silica surface. The bathochromic shift of the absorption spectrum of curcumin in decamethoxine solutions characterizes the polarization of its carbonyl group in supramolecular complexes. The hypsochromic shift in the absorption spectra of curcumin adsorbed from decamethoxine solutions on silica is explained by the violation of its conjugated π-bond system, resulted probably from the change in the spatial orientation of the curcumin molecule at the adsorption of its complexes on the sorbent surface. Curcumin is adsorbed on highly dispersed silica much more effectively from decamethoxine solutions than from aqueous solutions. The adsorption of curcumin is maximal (92 %) at a concentration of decamethoxine 0.002 M, and decreases sharply to 9 % in the micellar region of concentrations (≥ 0.008 M). The dependence of curcumin adsorption on decamethoxine concentration is described by a domed curve, which indicates a significant contribution of hydrophobic interactions to the formation of supramolecular complexes of curcumin with cationic surfactant and their adsorption on silica surface. The results obtained are of practical importance and can be used in the development of new, more effective medicines containing bioactive curcumin, antiseptic decamethoxine and silica enterosorbent.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132760329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Diamant, R. Lavrik, D. Starokadomsky, S. Gryn, V. Ogenko
A brief literature review proves that nanosized fluorescent carbon materials are widely used. In particular, they are promising in biomedicine (due to biocompatibility – for example, for biovisualization); optoelectronics; as chemical fluorescent sensors for measuring the concentration of metals, pH, anions, organic substances and biomolecules; as markers for fingerprinting. This paper investigates carbon materials obtained by oxidation of activated carbon, which are similar in their optical characteristics to carbon nanotubes. The aim of this work was the synthesis of nanocarbon material from available chemical raw materials. As a prototype, the synthesis is based on the method of obtaining carbon weakly acid cation-exchange resin. The nanocarbon material is easily dispersed in water, forming stable colloidal solutions that exhibit luminescence in the blue-green region of the visible spectrum. According to the results of thermogravimetric analysis, the thermal destruction of surface functional groups was found. The nature of the functional groups on the surface of the carbon nanomaterial was based on the obtained data of infrared spectra. The purity of the samples was monitored by X-ray diffraction analysis of the powder. For the pure sample, only the amorphous carbon spectrum was observed, and for the crude, NaCl reflexes were observed. In the region of MALDI positive ions, clusters of molecular mass have been obtained, which may belong to fullerene-like carbon structures. We believe that the high signal intensity at m/z 44 indicates a significant number of carboxyl groups. For aqueous solutions, the luminescence spectrum was measured, on which blue-green fluorescence was observed. Excitation by radiation with a wavelength was chosen based on the results of preliminary measurements of the dependence of the emission intensity on the length of the excitatory radiation. The fluorescence spectrum shows a wide maximum at 450 nm, which is slightly shifted to the long-wavelength region after centrifugation of the sample and precipitation of large fractions. The method of dynamic light scattering shows that particles with a wide range of sizes are present in the solution, the maximum distribution occurs in relatively large units.
{"title":"Synthesis and research of carbon nanodots and nanoparticles from activated carbon","authors":"V. Diamant, R. Lavrik, D. Starokadomsky, S. Gryn, V. Ogenko","doi":"10.15407/hftp13.03.321","DOIUrl":"https://doi.org/10.15407/hftp13.03.321","url":null,"abstract":"A brief literature review proves that nanosized fluorescent carbon materials are widely used. In particular, they are promising in biomedicine (due to biocompatibility – for example, for biovisualization); optoelectronics; as chemical fluorescent sensors for measuring the concentration of metals, pH, anions, organic substances and biomolecules; as markers for fingerprinting. This paper investigates carbon materials obtained by oxidation of activated carbon, which are similar in their optical characteristics to carbon nanotubes. The aim of this work was the synthesis of nanocarbon material from available chemical raw materials. As a prototype, the synthesis is based on the method of obtaining carbon weakly acid cation-exchange resin. The nanocarbon material is easily dispersed in water, forming stable colloidal solutions that exhibit luminescence in the blue-green region of the visible spectrum. According to the results of thermogravimetric analysis, the thermal destruction of surface functional groups was found. The nature of the functional groups on the surface of the carbon nanomaterial was based on the obtained data of infrared spectra. The purity of the samples was monitored by X-ray diffraction analysis of the powder. For the pure sample, only the amorphous carbon spectrum was observed, and for the crude, NaCl reflexes were observed. In the region of MALDI positive ions, clusters of molecular mass have been obtained, which may belong to fullerene-like carbon structures. We believe that the high signal intensity at m/z 44 indicates a significant number of carboxyl groups. For aqueous solutions, the luminescence spectrum was measured, on which blue-green fluorescence was observed. Excitation by radiation with a wavelength was chosen based on the results of preliminary measurements of the dependence of the emission intensity on the length of the excitatory radiation. The fluorescence spectrum shows a wide maximum at 450 nm, which is slightly shifted to the long-wavelength region after centrifugation of the sample and precipitation of large fractions. The method of dynamic light scattering shows that particles with a wide range of sizes are present in the solution, the maximum distribution occurs in relatively large units.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131685938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Vashchynskyi, I. V. Semkiv, A. Kashuba, R. Petrus
In this paper, changes in the porous structure of carbon material are investigated during chemical activation of apricot pit at different temperatures. The main purpose of the research has been to study the features of the internal micro- and mesostructure of the carbon surface, as well as to find patterns in the size distribution of pores dependent on the carbonization temperature of plant raw materials and subsequent chemical activation. The object of the study is porous carbon material, obtained from dried apricot fruit pits, pre-crushing, and cleaned from the core. This raw material has been carbonized at 300–900 °C with an interval of 100 °C and subjected to chemical activation by potassium hydroxide in the weight ratio XК, where ХК = m(KOH)/m(C). Thereby, a series of samples C3÷C9 has been obtained. The porous structure characteristics (specific surface area and total pore volume) of porous carbon material have been determined based on the analysis of nitrogen adsorption / desorption isotherms. It has been found that these materials have a frame structure with a large number of micropores. The analysis of literature data has revealed that the experimental curves belong to the isotherms that are characteristic of multilayer adsorption in micro- and mesopores of materials of organic origin. The hysteresis loop observed on these isotherms is related to the sorption processes in narrow pores. It has been found that carbonization of raw materials and chemical activation contribute to the cleaning of the frame structure, and there are acceptable modes of heat treatment of raw materials of plant origin, which determine the optimal pore size distribution and have a specific surface area S = (1042–1313) m2/g. With the help of scanning electron microscopy, the peculiarities of the formation of impurities on the surface of the original samples have been studied and their nature has been elucidated. It has been found that the largest total pore area has a sample carbonized at 600 ºC, and the largest pore volume Vtotal = 0.68 cm3/g for sample C3 is associated with a significant number of mesopores in the porous structure. As the carbonation temperature increases to 800-900 °C, narrow micropores degenerate and the carbon matrix transforms, resulting in a decrease in both the total pore area and the total porous volume.
{"title":"Influence of carbonization conditions on porous structure of carbon materials","authors":"V. Vashchynskyi, I. V. Semkiv, A. Kashuba, R. Petrus","doi":"10.15407/hftp13.03.349","DOIUrl":"https://doi.org/10.15407/hftp13.03.349","url":null,"abstract":"In this paper, changes in the porous structure of carbon material are investigated during chemical activation of apricot pit at different temperatures. The main purpose of the research has been to study the features of the internal micro- and mesostructure of the carbon surface, as well as to find patterns in the size distribution of pores dependent on the carbonization temperature of plant raw materials and subsequent chemical activation. The object of the study is porous carbon material, obtained from dried apricot fruit pits, pre-crushing, and cleaned from the core. This raw material has been carbonized at 300–900 °C with an interval of 100 °C and subjected to chemical activation by potassium hydroxide in the weight ratio XК, where ХК = m(KOH)/m(C). Thereby, a series of samples C3÷C9 has been obtained. The porous structure characteristics (specific surface area and total pore volume) of porous carbon material have been determined based on the analysis of nitrogen adsorption / desorption isotherms. It has been found that these materials have a frame structure with a large number of micropores. The analysis of literature data has revealed that the experimental curves belong to the isotherms that are characteristic of multilayer adsorption in micro- and mesopores of materials of organic origin. The hysteresis loop observed on these isotherms is related to the sorption processes in narrow pores. It has been found that carbonization of raw materials and chemical activation contribute to the cleaning of the frame structure, and there are acceptable modes of heat treatment of raw materials of plant origin, which determine the optimal pore size distribution and have a specific surface area S = (1042–1313) m2/g. With the help of scanning electron microscopy, the peculiarities of the formation of impurities on the surface of the original samples have been studied and their nature has been elucidated. It has been found that the largest total pore area has a sample carbonized at 600 ºC, and the largest pore volume Vtotal = 0.68 cm3/g for sample C3 is associated with a significant number of mesopores in the porous structure. As the carbonation temperature increases to 800-900 °C, narrow micropores degenerate and the carbon matrix transforms, resulting in a decrease in both the total pore area and the total porous volume.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130092633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The goal of this study is unraveling the specific features of non-stationary surface concentration distribution of electroactive and inactive species in a model electrochemical process with a preceding homogeneous first-order chemical reaction (CE mechanism). For this purpose, the exact analytical expressions for the non-stationary concentration distributions of electroactive and inactive species in the thin layer attached to a planar electrode are analyzed. The both cases of equal and unequal diffusion coefficients of species taking part in the preceding chemical reaction are considered. In the former case, the exact analytical expressions for the concentration distributions of electroactive and inactive species on a planar electrode are obtained. The peculiarities of the limiting cases of zero and infinite frequency of an applied alternating current for the both cases of equal and unequal diffusion coefficients of species are discussed. It is shown that there is a phase shift between AC and the surface concentration of species that changes under the action of this current. At low frequencies, the phase angle tends to p/2, whereas at high frequencies it decreases to p/4. The phase angle is the function of the two important measures, namely, the ratio of the Nernst diffusion layer thickness to the oscillation diffusion layer thickness, and the ratio of the Nernst diffusion layer thickness to the reaction layer one. It is shown that the phase angle depends on the diffusion coefficient of species in different manner for low and high values of the rate constants of the chemical reaction. At low values of these parameters, the phase angle shifts slightly to the range of high frequencies with an increase of diffusion coefficient. At the high rate constants, the phase angle decreases with frequency more slowly, and its dependence on diffusion coefficient is observed only at middle frequencies. The surface concentration of electroactive and inactive species decreases with an increase of frequency, but for the inactive species this process is faster than that for the electroactive species. The influence of the inactive species on the surface concentration of electroactive species decreases at high frequencies and at low rate constants of the preceding chemical reaction. The results obtained shed the light on complex dynamics at an electrode/electrolyte interface under non-stationary conditions.
{"title":"Analytical expressions for surface concentration distribution in a model electrochemical process with a preceding chemical reaction","authors":"O. I. Gichan","doi":"10.15407/hftp13.03.239","DOIUrl":"https://doi.org/10.15407/hftp13.03.239","url":null,"abstract":"The goal of this study is unraveling the specific features of non-stationary surface concentration distribution of electroactive and inactive species in a model electrochemical process with a preceding homogeneous first-order chemical reaction (CE mechanism). For this purpose, the exact analytical expressions for the non-stationary concentration distributions of electroactive and inactive species in the thin layer attached to a planar electrode are analyzed. The both cases of equal and unequal diffusion coefficients of species taking part in the preceding chemical reaction are considered. In the former case, the exact analytical expressions for the concentration distributions of electroactive and inactive species on a planar electrode are obtained. The peculiarities of the limiting cases of zero and infinite frequency of an applied alternating current for the both cases of equal and unequal diffusion coefficients of species are discussed. It is shown that there is a phase shift between AC and the surface concentration of species that changes under the action of this current. At low frequencies, the phase angle tends to p/2, whereas at high frequencies it decreases to p/4. The phase angle is the function of the two important measures, namely, the ratio of the Nernst diffusion layer thickness to the oscillation diffusion layer thickness, and the ratio of the Nernst diffusion layer thickness to the reaction layer one. It is shown that the phase angle depends on the diffusion coefficient of species in different manner for low and high values of the rate constants of the chemical reaction. At low values of these parameters, the phase angle shifts slightly to the range of high frequencies with an increase of diffusion coefficient. At the high rate constants, the phase angle decreases with frequency more slowly, and its dependence on diffusion coefficient is observed only at middle frequencies. The surface concentration of electroactive and inactive species decreases with an increase of frequency, but for the inactive species this process is faster than that for the electroactive species. The influence of the inactive species on the surface concentration of electroactive species decreases at high frequencies and at low rate constants of the preceding chemical reaction. The results obtained shed the light on complex dynamics at an electrode/electrolyte interface under non-stationary conditions.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126220863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Gerashchenko, K. O. Stepanyuk, O. Chepliaka, M. Borysenko, E. Pakhlov, D. G. Klyuchkov, K. G. Vinogradova
Неaling of infected ulcers and wounds, particularly in older people, is a serious problem in modern surgery. As a result of many years efforts, we have created an innovative wound care composition that has high absorptive, anti-inflammatory and wound-healing capabilities and are starting the clinical study of it. The composition, which got a trade mark Pathelen®, contains nanoscale hydrophilic silica (A-300), hydrophobic silica (Aerosil® R972 Pharma) and benzalkonium chloride. This work aimed to develop an optimal pathway of industrial production, as well as methods of quality control of the drug. The examination of manufacture intermediates and the final product includes bulk density measurement, thermal analysis, IR spectroscopy, chemical methods of identification, adsorption capacity and microbial contamination control. The pathway of manufacture which consists of mechanochemical immobilization of benzalkonium chloride on hydrophobic silica surface and mixing of obtained semi-product with hydrophilic nanoscale silica is developed. Thus, a technological method is proposed for combining hydrophilic and hydrophobic nanomaterials in one preparation. The final product complies to the elaborated quality parameters. In particular, the bulk density is distributed in a range 50–60 g/L, the adsorption capacity is not less than 140 mg of protein per gram. The absence of pathogenic microorganisms and fungi was demonstrated; the quantity of non-pathogenic microorganisms meets the requirements of the European Pharmacopoeia for products in this category. The results obtained can be useful for the organization a large-scale production of the proposed drug in future.
{"title":"Hydrophilic/hydrophobic wound care preparation based on the nanoscale silica: physicochemical and technological aspects","authors":"I. Gerashchenko, K. O. Stepanyuk, O. Chepliaka, M. Borysenko, E. Pakhlov, D. G. Klyuchkov, K. G. Vinogradova","doi":"10.15407/hftp13.02.160","DOIUrl":"https://doi.org/10.15407/hftp13.02.160","url":null,"abstract":"Неaling of infected ulcers and wounds, particularly in older people, is a serious problem in modern surgery. As a result of many years efforts, we have created an innovative wound care composition that has high absorptive, anti-inflammatory and wound-healing capabilities and are starting the clinical study of it. The composition, which got a trade mark Pathelen®, contains nanoscale hydrophilic silica (A-300), hydrophobic silica (Aerosil® R972 Pharma) and benzalkonium chloride. This work aimed to develop an optimal pathway of industrial production, as well as methods of quality control of the drug. The examination of manufacture intermediates and the final product includes bulk density measurement, thermal analysis, IR spectroscopy, chemical methods of identification, adsorption capacity and microbial contamination control. The pathway of manufacture which consists of mechanochemical immobilization of benzalkonium chloride on hydrophobic silica surface and mixing of obtained semi-product with hydrophilic nanoscale silica is developed. Thus, a technological method is proposed for combining hydrophilic and hydrophobic nanomaterials in one preparation. The final product complies to the elaborated quality parameters. In particular, the bulk density is distributed in a range 50–60 g/L, the adsorption capacity is not less than 140 mg of protein per gram. The absence of pathogenic microorganisms and fungi was demonstrated; the quantity of non-pathogenic microorganisms meets the requirements of the European Pharmacopoeia for products in this category. The results obtained can be useful for the organization a large-scale production of the proposed drug in future.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129289841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kartel, K. Voitko, Y. Grebelna, S. Zhuravskyi, K. Ivanenko, T. Kulyk, S. Makhno, Y. Sementsov
The aim of the current study was to find changes in the structure and state of the surface of graphene oxide (GO) under the conditions of its reduction and modification by hetero atoms of nitrogen and amino acids. Reduction of GO was performed with hydrazine hydrate (R-GO), doping with nitrogen atoms - urea impregnation and subsequent heat treatment (N-GO), and the surface of GO was modified with sulfur-containing amino acid – L-cysteine by nucleophilic addition (L-GO). The samples obtained were characterized by analytical methods, such as Raman scattering, IR spectroscopy, TPD-mass-spectrometry, dynamic light scattering spectroscopy. The available Raman spectra indicate a defective structure of GO, reduction of GO leads to greater ordering of the structure in relation to GO, nitrating and modification by amino acid - to the opposite effect, a slight deterioration of the structural state. According to the results of IR spectroscopy, also confirmed by TPD-MS, GO has a large number of functional surface groups: (OH), (C=O), (C=C), (C-O-C), (CO-O-CO), (CH). Hydrazine reduction completely hydrophobizes the surface, in the IR spectra there is only a peak at ~ 1040 cm–1, which corresponds to CO-O-CO vibrations, with significantly reduced intensity, as well as bands at 2120 and 2300 cm–1, which indicate the aromatic nature of the samples and exist in all GO derivatives. In nitrogen and sulfur-containing samples (L-GO) a new peak of ~ 1520 cm–1appears, which corresponds to N-H vibrations in amines. Sulfur-containing derivatives have valence vibrations at 600 cm–1, which most likely corresponds to S-H bonds. Thus, modification of GO leads to a significant change in its structure and surface chemistry, which in turn affects the capability of the obtained samples to capture free radicals. Previous empirical studies have shown that this property increases in the series L-GO > GO > N-GO > R-GO.
本研究的目的是发现氧化石墨烯(GO)在氮和氨基酸杂原子还原和修饰的条件下，其表面结构和状态的变化。通过水合肼(R-GO)、氮原子掺杂-尿素浸渍和热处理(N-GO)还原氧化石墨烯，并通过亲核加成(L-GO)对氧化石墨烯表面进行含硫氨基酸- l -半胱氨酸修饰。采用拉曼散射、红外光谱、tpd质谱、动态光散射等分析方法对样品进行了表征。可用的拉曼光谱表明氧化石墨烯的结构有缺陷，氧化石墨烯的还原导致与氧化石墨烯相关的结构更有序，氨基酸的硝化和修饰-相反的效果，结构状态轻微恶化。红外光谱结果和TPD-MS证实，氧化石墨烯具有大量的表面官能团:(OH)、(C=O)、(C=C)、(C-O-C)、(CO-O-CO)、(CH)。在红外光谱中，仅在~ 1040 cm-1处有一个峰，对应于CO-O-CO振动，强度明显减弱;在2120和2300 cm-1处有两个谱带，表明样品具有芳香性，所有GO衍生物都存在。在含氮和含硫样品(L-GO)中，出现了~ 1520 cm - 1的新峰，对应于胺中的N-H振动。含硫衍生物的价振动在600 cm-1，这很可能对应于S-H键。因此，氧化石墨烯的修饰会导致其结构和表面化学发生重大变化，从而影响所得样品捕获自由基的能力。以往的实证研究表明，该性质的增加顺序为L-GO > GO > N-GO > R-GO。
{"title":"Changes in the structure and properties of graphene oxide surfaces during reduction and modification","authors":"M. Kartel, K. Voitko, Y. Grebelna, S. Zhuravskyi, K. Ivanenko, T. Kulyk, S. Makhno, Y. Sementsov","doi":"10.15407/hftp13.02.179","DOIUrl":"https://doi.org/10.15407/hftp13.02.179","url":null,"abstract":"The aim of the current study was to find changes in the structure and state of the surface of graphene oxide (GO) under the conditions of its reduction and modification by hetero atoms of nitrogen and amino acids. Reduction of GO was performed with hydrazine hydrate (R-GO), doping with nitrogen atoms - urea impregnation and subsequent heat treatment (N-GO), and the surface of GO was modified with sulfur-containing amino acid – L-cysteine by nucleophilic addition (L-GO). The samples obtained were characterized by analytical methods, such as Raman scattering, IR spectroscopy, TPD-mass-spectrometry, dynamic light scattering spectroscopy. The available Raman spectra indicate a defective structure of GO, reduction of GO leads to greater ordering of the structure in relation to GO, nitrating and modification by amino acid - to the opposite effect, a slight deterioration of the structural state. According to the results of IR spectroscopy, also confirmed by TPD-MS, GO has a large number of functional surface groups: (OH), (C=O), (C=C), (C-O-C), (CO-O-CO), (CH). Hydrazine reduction completely hydrophobizes the surface, in the IR spectra there is only a peak at ~ 1040 cm–1, which corresponds to CO-O-CO vibrations, with significantly reduced intensity, as well as bands at 2120 and 2300 cm–1, which indicate the aromatic nature of the samples and exist in all GO derivatives. In nitrogen and sulfur-containing samples (L-GO) a new peak of ~ 1520 cm–1appears, which corresponds to N-H vibrations in amines. Sulfur-containing derivatives have valence vibrations at 600 cm–1, which most likely corresponds to S-H bonds. Thus, modification of GO leads to a significant change in its structure and surface chemistry, which in turn affects the capability of the obtained samples to capture free radicals. Previous empirical studies have shown that this property increases in the series L-GO > GO > N-GO > R-GO.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130816055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Zolotarenko, M. Ualkhanova, E. Rudakova, N. Akhanova, A. Zolotarenko, D. Shchur, M. Gabdullin, N. Gavrylyuk, A. Zolotarenko, M. Chymbai, I. Zagorulko, O. Havryliuk
A review of more than 100 contemporary literary works of domestic and foreign researchers on the issues of electric arc synthesis (EAS) of various carbon nanostructures (CNS) has been performed. EAS CNScan be performed in both gaseous and liquid media. EAS in a gaseous medium has a number of advantages, such as high productivity and velocity of the condensation process, as well as ease of control.But this method of synthesis also has disadvantages: it requires a complex vacuum and cooling system, which makes the installation very cumbersome.In addition, this method does not solve the problem of agglomeration of synthesized CNS and has a by-product of synthesis in the form of growth (deposit) on the electrode. EAS in a liquid medium is more compact equipment, as it does not require systems of vacuum (the process takes place at atmospheric pressure) and cooling (liquid medium plays the role of heat dissipation).This method of synthesis uses different types of dielectric liquids – from distilled water (H2O), liquid nitrogen (N2) to hydrocarbon solvents, which can serve as a source of carbon in the synthesis zone.By changing the composition of the liquid phase, it is possible to achieve the synthesis of different types of CNS.Also, this method involves the use of metal electrodes, which, in addition to long service life, can act as catalysts.The metal particles can be encapsulated ANS, forming composites with different magnetic properties.In some studies, it has been shown that mixtures of metal carbides can be formed when metal electrodes are used in the EAS process in a liquid medium.The liquid medium after EASCNS is also of scientific interest. Probably, the liquid medium contains new modifications of soluble organic compounds, which are being researched by researchers around the world.Thus, scientists have found that after EAS in a liquid medium using graphite electrodes, the working solution (C6H6) changed its color.This indicates the formation of soluble organic compounds in it. In the literature review on the basis of literature data the table of modes for industrial synthesis of single-walled CNS is created.Also, a list of modes for the creation of defective CNS as a method of increasing the area of adsorption in nanoparticles. The solution of important problems of the EAS method is recorded: agglomeration of CNS; the problem of forming a deposit; increase productivity.
{"title":"Advantages and disadvantages of electric arc methods for the synthesis of carbon nanostructures","authors":"O. Zolotarenko, M. Ualkhanova, E. Rudakova, N. Akhanova, A. Zolotarenko, D. Shchur, M. Gabdullin, N. Gavrylyuk, A. Zolotarenko, M. Chymbai, I. Zagorulko, O. Havryliuk","doi":"10.15407/hftp13.02.209","DOIUrl":"https://doi.org/10.15407/hftp13.02.209","url":null,"abstract":"A review of more than 100 contemporary literary works of domestic and foreign researchers on the issues of electric arc synthesis (EAS) of various carbon nanostructures (CNS) has been performed. EAS CNScan be performed in both gaseous and liquid media. EAS in a gaseous medium has a number of advantages, such as high productivity and velocity of the condensation process, as well as ease of control.But this method of synthesis also has disadvantages: it requires a complex vacuum and cooling system, which makes the installation very cumbersome.In addition, this method does not solve the problem of agglomeration of synthesized CNS and has a by-product of synthesis in the form of growth (deposit) on the electrode. EAS in a liquid medium is more compact equipment, as it does not require systems of vacuum (the process takes place at atmospheric pressure) and cooling (liquid medium plays the role of heat dissipation).This method of synthesis uses different types of dielectric liquids – from distilled water (H2O), liquid nitrogen (N2) to hydrocarbon solvents, which can serve as a source of carbon in the synthesis zone.By changing the composition of the liquid phase, it is possible to achieve the synthesis of different types of CNS.Also, this method involves the use of metal electrodes, which, in addition to long service life, can act as catalysts.The metal particles can be encapsulated ANS, forming composites with different magnetic properties.In some studies, it has been shown that mixtures of metal carbides can be formed when metal electrodes are used in the EAS process in a liquid medium.The liquid medium after EASCNS is also of scientific interest. Probably, the liquid medium contains new modifications of soluble organic compounds, which are being researched by researchers around the world.Thus, scientists have found that after EAS in a liquid medium using graphite electrodes, the working solution (C6H6) changed its color.This indicates the formation of soluble organic compounds in it. In the literature review on the basis of literature data the table of modes for industrial synthesis of single-walled CNS is created.Also, a list of modes for the creation of defective CNS as a method of increasing the area of adsorption in nanoparticles. The solution of important problems of the EAS method is recorded: agglomeration of CNS; the problem of forming a deposit; increase productivity.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132925898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This paper presents a theory that allows one to calculate the energy absorbed by spheroidal metal nanoparticles when irradiated by ultrashort laser pulses of different duration in the region of surface plasmon resonance. Simple analytical expressions are obtained to calculate the absorption energy dependent on the frequency of carrier laser wave, on the pulse duration, and on the ratio between the axes of the ellipsoids. It is shown that at the frequency of the carrier (laser) wave, which coincides with that of the surface plasmon, the maximum absorption is observed for spherical nanoparticles. As the carrier frequency deviates from the surface plasmon one, two maxima appear in the absorption spectrum, dependent on the ratio of spheroidal axes: one corresponds to the elongated particles and the other to the flattened ones.
{"title":"Kinetic theory of absorption of ultrashort laser pulses by ensembles of metallic nanoparticles under conditions of surface plasmon resonance","authors":"A. Biliuk, O. Semchuk, O. Havryliuk","doi":"10.15407/hftp13.02.190","DOIUrl":"https://doi.org/10.15407/hftp13.02.190","url":null,"abstract":"This paper presents a theory that allows one to calculate the energy absorbed by spheroidal metal nanoparticles when irradiated by ultrashort laser pulses of different duration in the region of surface plasmon resonance. Simple analytical expressions are obtained to calculate the absorption energy dependent on the frequency of carrier laser wave, on the pulse duration, and on the ratio between the axes of the ellipsoids. It is shown that at the frequency of the carrier (laser) wave, which coincides with that of the surface plasmon, the maximum absorption is observed for spherical nanoparticles. As the carrier frequency deviates from the surface plasmon one, two maxima appear in the absorption spectrum, dependent on the ratio of spheroidal axes: one corresponds to the elongated particles and the other to the flattened ones.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"68 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133308866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kartel, L. Karachevtseva, Y. Sementsov, O. Lytvynenko
The possibilities to enhance the properties of nanostructured surfaces are evaluated on “polymer-multiwall carbon nanotube” composites. Influence of sp3 hybridization bonds is investigated in composites derived from polypropylene, polyamide-6, polyamide-12 and polyvinyl chloride after adding CNTs to polymers. IR absorption of “polymer-CNTs” films exceeds that of polymer by 10-103 times in the entire measured spectral range. In addition, two-polar IR absorption are measured on composites with negative components at spectral positions of “D-band” and “2D-band” of sp3 hybridization. In this case, the greater oscillation amplitudes of C-C, CH2 and CH3 bonds correspond to a higher absorption at the vibration frequencies γω(CН) and γω(CH2). Two-polar oscillations of absorption with a negative component in the spectral band ranges “D” and “2D” of sp3 hybridization in nanotubes have been measured for the composites. Frequencies of 2D-band correspond to the second order frequencies of D-band. The intensity of 2D band increases with an increase in the concentration of defects. The absorption of light increases when the frequencies of local oscillations of surface bonds in carbon nanotubes correspond to the frequencies of slotted modes along the boundary of the “nanotube polymer” (surface polaritons). Two-polar oscillations have an ultra-small half width 0.4–0.6 cm–1, which indicates a strong interaction of surface polaritons with photons. Vertically polarized light along carbon nanotubes and horizontally polarized light of D and 2D bands resulted in light beams splitting, two-photon interference and realization of the quantum Hong-Ou-Mandel effect.
{"title":"Hong-Ou-Mandel quantum effect on “polymer - multiwall cnt” composites","authors":"M. Kartel, L. Karachevtseva, Y. Sementsov, O. Lytvynenko","doi":"10.15407/hftp13.02.170","DOIUrl":"https://doi.org/10.15407/hftp13.02.170","url":null,"abstract":"The possibilities to enhance the properties of nanostructured surfaces are evaluated on “polymer-multiwall carbon nanotube” composites. Influence of sp3 hybridization bonds is investigated in composites derived from polypropylene, polyamide-6, polyamide-12 and polyvinyl chloride after adding CNTs to polymers. IR absorption of “polymer-CNTs” films exceeds that of polymer by 10-103 times in the entire measured spectral range. In addition, two-polar IR absorption are measured on composites with negative components at spectral positions of “D-band” and “2D-band” of sp3 hybridization. In this case, the greater oscillation amplitudes of C-C, CH2 and CH3 bonds correspond to a higher absorption at the vibration frequencies γω(CН) and γω(CH2). Two-polar oscillations of absorption with a negative component in the spectral band ranges “D” and “2D” of sp3 hybridization in nanotubes have been measured for the composites. Frequencies of 2D-band correspond to the second order frequencies of D-band. The intensity of 2D band increases with an increase in the concentration of defects. The absorption of light increases when the frequencies of local oscillations of surface bonds in carbon nanotubes correspond to the frequencies of slotted modes along the boundary of the “nanotube polymer” (surface polaritons). Two-polar oscillations have an ultra-small half width 0.4–0.6 cm–1, which indicates a strong interaction of surface polaritons with photons. Vertically polarized light along carbon nanotubes and horizontally polarized light of D and 2D bands resulted in light beams splitting, two-photon interference and realization of the quantum Hong-Ou-Mandel effect.","PeriodicalId":296392,"journal":{"name":"Himia, Fizika ta Tehnologia Poverhni","volume":"293 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114686880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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