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Total abdominal hysterectomy in a Tertiary Hospital in Kumasi: Indication, Histopathological Findings and Clinicopathological Correlation 库马西一家三级医院的全腹子宫切除术:指征、组织病理学表现和临床病理相关性
IF 0.4 Pub Date : 2018-06-01 DOI: 10.4314/jmbs.v7i1.3
N. Titiloye, B. Duduyemi, E. Asiamah, I. Okai, P. Ossei, Thomas Okpoti Konney, P. Fefemwole
Hysterectomy is the commonest gynaecological surgery worldwide. Hysterectomy is commonly performed in our centre with request for post-surgical histological confirmation of pathologies. The aim of this study was to review all the hysterectomy specimens sent to our department between 2008 and 2016 and analyse the histological diagnosis in them and clinically correlate with the indications for the surgery. We reviewed retrospectively request forms, histological reports and slides generated for all cases of hysterectomies sent to our department for histological assessment between 2008 and 2016 totalling 1086. All the data obtained were analysed using SPSS 21. A total number of 1086 cases of hysterectomies with or without salpingooophorectomy were received in our department. The age range was 15 to 85 years with age group 40 to 49 years constituting 57.7% of cases. The commonest indication for surgery was uterine mass which constituted 722 cases (66.42%) and an obvious uterine mass was found at grossing in 737 cases (66.48%) while histology revealed uterine leiomyoma in 861 cases (79.28%) constituting the largest proportion of histological diagnosis. Other indications for surgery include dysfunctional uterine bleeding, suspected ovarian and cervical malignancy and peri-partum haemorrhage. Histological diagnoses confirmed wide range of lesions within the endometrium, cervix, fallopian tubes and ovaries. There was correlation between clinical indication and histological diagnosis up to 90.2% of all cases. Our data confirmed hysterectomy specimens with or without salpingo-oophorectomy as a common histological specimen in our laboratory, with peak age of patients in the fifth decade. Leiomyoma was the commonest histological finding and other wide ranges of pathologies were seen with strong positive (r = 0.98) correlation between pre-operative indication and the final diagnosis.Journal of Medical and Biomedical Sciences (2018) 7(1), 22 - 28
子宫切除术是全世界最常见的妇科手术。子宫切除术通常在我们中心进行,要求术后组织学确认病理。本研究的目的是回顾2008年至2016年间发送到我科的所有子宫切除术标本,并分析其中的组织学诊断以及与手术指征的临床相关性。我们回顾性审查了2008年至2016年间发送到我科进行组织学评估的所有子宫切除术病例的申请表、组织学报告和幻灯片,共计1086份。所有数据均使用SPSS 21进行分析。我科共接受了1086例子宫切除术,包括或不包括输卵管卵母细胞切除术。年龄范围为15至85岁,年龄组为40至49岁,占病例的57.7%。最常见的手术指征是子宫肿块,占722例(66.42%),737例(66.48%)发现明显的子宫肿块,861例(79.28%)组织学显示子宫平滑肌瘤,占组织学诊断的最大比例。手术的其他适应症包括功能失调的子宫出血、疑似卵巢和宫颈恶性肿瘤以及围产期出血。组织学诊断证实子宫内膜、宫颈、输卵管和卵巢有广泛的病变。临床指征与组织学诊断的相关性高达90.2%。我们的数据证实,无论是否进行输卵管卵巢切除术,子宫切除术标本都是我们实验室中常见的组织学标本,患者的峰值年龄在第五个十年。平滑肌瘤是最常见的组织学发现,其他广泛的病理学表现与术前适应症和最终诊断之间有很强的正相关(r=0.98)。医学与生物医学科学杂志(2018)7(1),22-28
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引用次数: 2
Prevalence, patterns and predictors of self-medication with anti-malarial drugs among Cameroonian mothers during a recent illness episode 喀麦隆母亲在最近一次发病期间使用抗疟疾药物自我治疗的流行程度、模式和预测因素
IF 0.4 Pub Date : 2018-06-01 DOI: 10.4314/jmbs.v7i1.4
L. Kojom, A. A. Ntoumba, H. N. Nyabeyeu, G. B. Wepnje, C. Tonga, L. Lehman
Artemisinin-based combination therapies (ACTs) are recommended as treatment of choice for malaria. Although the resistance to artemisinin and its derivatives has not yet been officially reported in Africa, there is growing concern that it may reach the continent. Self-medication is common among African populations and may explained drug resistance. Unfortunately, a few studies have addressed this issue in Cameroon. This study seeks to appraise the prevalence, patterns and predictors of antimalarial self-medication. A household-based cross-sectional study was conducted in 2016 in the town of Douala. Interviews and pretested semi-structured questionnaires were administered for collecting information from 213 mothers of under-fives. The prevalence of self-medication was 49.30%. The main reasons were “habit” (38.75%), “Lack of money” (22.48%) and “Lightness of symptoms” (13.18 %). Pharmacy (47.80%) and street medicine stores (30.19%) were the commonest drug providers. Nearly 20% of women had not respected posology although treatment was right and taken promptly. Age, level of education and curiosity on treatment were risk factors of self-medication. Our study confirms that malaria self-medication is common among women and the influence of some factors. Hence, strategies for information, education and communication should be scaled up to efficiently address self-medication in the area.Journal of Medical and Biomedical Sciences (2018) 7(1), 29 - 39
推荐以青蒿素为基础的联合疗法作为治疗疟疾的选择。尽管非洲尚未正式报告对青蒿素及其衍生物的耐药性,但人们越来越担心这种耐药性可能会传播到非洲大陆。自我用药在非洲人口中很常见,这可能解释了耐药性。不幸的是,喀麦隆的一些研究已经解决了这个问题。本研究旨在评估抗疟疾自我药物治疗的流行程度、模式和预测因素。2016年在杜阿拉镇进行了一项以家庭为基础的横断面研究。对213名五岁以下儿童的母亲进行了访谈和预测半结构化问卷调查。自我药疗率为49.30%。主要原因是“习惯”(38.75%)、“缺钱”(22.48%)和“症状轻”(13.18%)。药房(47.80%)和街头药店(30.19%)是最常见的药物提供者。近20%的女性不尊重病理学,尽管治疗是正确和及时的。年龄、文化程度和对治疗的好奇心是自我药疗的危险因素。我们的研究证实,疟疾自我药疗在妇女中很常见,并且受到一些因素的影响。因此,应扩大信息、教育和交流战略,以有效解决该地区的自我药疗问题。医学与生物医学杂志,2018,7(1),29 - 39
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引用次数: 9
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Journal of Medical and Biomedical Science
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