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Urologie Kolumne. 泌尿科科鲁姆内
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 DOI: 10.1007/s00120-024-02458-5
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引用次数: 0
[Novel systemic treatment options for advanced bladder cancer]. [晚期膀胱癌的新型系统治疗方案]。
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 Epub Date: 2024-08-29 DOI: 10.1007/s00120-024-02413-4
C Aydogdu, I Brinkmann, J Casuscelli

Systemic treatment of urothelial carcinoma of the bladder requires complex approaches and is constantly evolving. Neoadjuvant cisplatin-based chemotherapy followed by radical cystectomy remains the current standard of care for muscle-invasive advanced bladder cancer. For patients ineligible for cisplatin, adjuvant treatment with nivolumab is recommended. Innovative perioperative combinations could transform the treatment landscape in the future. First-line treatment for metastatic urothelial carcinoma has long been dominated by platinum-based combinations, recently followed by the immune checkpoint inhibitor avelumab as maintenance therapy; however, recent results on the use of enfortumab vedotin and pembrolizumab in the first-line setting are expected to fundamentally change the treatment options. In subsequent lines of treatment, the not yet approved erdafitinib, as the first targeted therapy for advanced urothelial carcinoma, offers an important alternative and underscores the need for molecular testing.

膀胱尿路上皮癌的系统治疗需要复杂的方法，并且在不断发展。以顺铂为基础的新辅助化疗和根治性膀胱切除术仍是目前治疗肌肉浸润性晚期膀胱癌的标准疗法。对于不符合顺铂治疗条件的患者，建议使用 nivolumab 进行辅助治疗。创新的围手术期联合疗法可能会改变未来的治疗格局。长期以来，转移性尿路上皮癌的一线治疗一直是以铂类药物为基础的联合疗法，最近又开始使用免疫检查点抑制剂阿维列单抗作为维持治疗；然而，最近在一线治疗中使用恩福单抗维多汀和pembrolizumab的结果有望从根本上改变治疗方案。在后续治疗中，尚未获批的厄达菲替尼作为晚期尿路上皮癌的第一种靶向疗法，提供了一种重要的替代疗法，并强调了分子检测的必要性。
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引用次数: 0
[Early sources of urologic and venereologic sexual medicine from Vienna : Protagonists at the interface of two new medical specialties]. [维也纳泌尿学和性病学性医学的早期来源：两个新医学专科交界处的主角]。
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 Epub Date: 2024-08-27 DOI: 10.1007/s00120-024-02392-6
Friedrich H Moll, Heiner Fangerau

The Austrian Society for the Promotion of Sexual Medicine and Sexual Health (Österreichische Gesellschaft zur Förderung der Sexualmedizin und der Sexuellen Gesundheit [ÖGFSSG]) was founded in 2014. This foundation looked back upon the increasing efforts to develop this field of academic knowledge since the middle of the 19th century, in which Viennese medicine played an important role. This article highlights key Viennese players who had a particular interest in sexual medicine from a urological perspective around 1900. They worked in the wider area of several disciplines, striving for specialization in the environment of a rapidly growing metropolis with multiple cultural influences. The scholars presented here as a collection of sources contributed to the upswing in sexual medicine through their work by venturing into an area in which no medical or other discipline had previously been able to claim sovereignty of interpretation.

奥地利性医学和性健康促进会（Österreichische Gesellschaft zur Förderung der Sexualmedizin und der Sexuellen Gesundheit [ÖGFSSG]）成立于2014年。该基金会回顾了自19世纪中叶以来为发展这一学术知识领域所付出的日益艰辛的努力，维也纳医学在其中发挥了重要作用。本文重点介绍了1900年前后从泌尿科角度对性医学特别感兴趣的维也纳重要人物。他们涉猎多个学科，在快速发展的大都市环境中努力实现专业化，并受到多种文化的影响。这里介绍的这些学者通过他们的工作，涉足了一个医学或其他学科以前都无法宣称拥有解释权的领域，从而为性医学的发展做出了贡献。
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引用次数: 0
[Andrology]. [Andrology].
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 Epub Date: 2024-11-08 DOI: 10.1007/s00120-024-02460-x
Sabine Kliesch, Thorsten Diemer, Armin Soave, Herbert Sperling
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引用次数: 0
Berufspolitik BvDU. 专业政策 BvDU。
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 DOI: 10.1007/s00120-024-02467-4
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引用次数: 0
BvDU Kurz notiert. BvDU 简介。
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 DOI: 10.1007/s00120-024-02468-3
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引用次数: 0
GeSRU. GeSRU.
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 DOI: 10.1007/s00120-024-02463-8
{"title":"GeSRU.","authors":"","doi":"10.1007/s00120-024-02463-8","DOIUrl":"10.1007/s00120-024-02463-8","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":"63 11","pages":"1209-1210"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitteilungen der DGU. 总干事室函件。
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 DOI: 10.1007/s00120-024-02466-5
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引用次数: 0
Termine. 日期
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 DOI: 10.1007/s00120-024-02470-9
{"title":"Termine.","authors":"","doi":"10.1007/s00120-024-02470-9","DOIUrl":"10.1007/s00120-024-02470-9","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":"63 11","pages":"1213-1214"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Testosterone replacement therapy and possible side effects]. [睾酮替代疗法和可能的副作用]。
IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie
Pub Date : 2024-11-01 Epub Date: 2024-10-10 DOI: 10.1007/s00120-024-02455-8
Michael Zitzmann, Martin C Michel, Herbert Sperling

The substitution of testosterone is basic andrological treatment. Beside the "when and how," knowledge of possible side effects is mandatory. Therefore, we highlight the effects of testosterone replacement therapy on bones, cardiac function, sexuality, gynacomatia, fertility, and contraception, but also areas of concern regarding prostate carcinoma and testosterone replacement therapy.

睾丸激素替代品是最基本的生理治疗方法。除了 "何时、如何"，了解可能的副作用也是必须的。因此，我们将重点介绍睾酮替代疗法对骨骼、心脏功能、性功能、妇科炎症、生育能力和避孕的影响，以及前列腺癌和睾酮替代疗法的相关注意事项。
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引用次数: 0
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