Pub Date : 2022-03-01DOI: 10.23736/s2724-542x.21.02840-6
J. R. Fiore, M. Di Stefano, M. R. Lipsi, F. Antonucci, Tommaso Granato, G. Faleo, S. Bruno, F. Arena, M. Margaglione, M. Centra
{"title":"Lack of plasma viremia in SARS-CoV-2 seropositive blood donors carrying the virus in nasopharyngeal swabs argues against potential transmission of COVID-19 through blood","authors":"J. R. Fiore, M. Di Stefano, M. R. Lipsi, F. Antonucci, Tommaso Granato, G. Faleo, S. Bruno, F. Arena, M. Margaglione, M. Centra","doi":"10.23736/s2724-542x.21.02840-6","DOIUrl":"https://doi.org/10.23736/s2724-542x.21.02840-6","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79930955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.23736/s2724-542x.20.02669-5
Roopshikha Sahu, Amisha Yadav, A. Nath
{"title":"Estimation of maximum recommended therapeutic dose of anti-retroviral drugs using diversified sampling and varied descriptors","authors":"Roopshikha Sahu, Amisha Yadav, A. Nath","doi":"10.23736/s2724-542x.20.02669-5","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02669-5","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82842410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.23736/s2724-542x.20.02734-2
L. Salmi, F. Patrucco, L. Molinari, M. Bellan, P. Sainaghi, L. Castello
{"title":"ADAM17 inhibition effects on Mer shedding","authors":"L. Salmi, F. Patrucco, L. Molinari, M. Bellan, P. Sainaghi, L. Castello","doi":"10.23736/s2724-542x.20.02734-2","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02734-2","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72408049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.23736/s2724-542x.21.02753-1
N. Vu, T. T. Dao, N. Truong, H. Nguyen, P. Pham
{"title":"The immunomodulation of osteoblasts and chondroblasts differentiated from programmed death-ligand 1-positive mesenchymal stem cells","authors":"N. Vu, T. T. Dao, N. Truong, H. Nguyen, P. Pham","doi":"10.23736/s2724-542x.21.02753-1","DOIUrl":"https://doi.org/10.23736/s2724-542x.21.02753-1","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84121972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.23736/s2724-542x.20.02642-7
T. R. Poorani, Selvam Iswarya, M. Priya, Sri D. Sivakumar, S. Kannan
{"title":"Fabrication of medicinal transdermal patch impregnated with silver nanoparticles synthesized from biomedical photographic wastes","authors":"T. R. Poorani, Selvam Iswarya, M. Priya, Sri D. Sivakumar, S. Kannan","doi":"10.23736/s2724-542x.20.02642-7","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02642-7","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82956870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.23736/s2724-542x.20.02739-1
J. Cusato, A. Calcagno, M. Antonucci, L. Marinaro, V. Avataneo, A. de Nicolò, S. Bonora, G. di Perri, A. D’Avolio
{"title":"A pharmacogenetic study in HIV-infected patients treated with ritonavir: hematological and cardiovascular disease risk analysis","authors":"J. Cusato, A. Calcagno, M. Antonucci, L. Marinaro, V. Avataneo, A. de Nicolò, S. Bonora, G. di Perri, A. D’Avolio","doi":"10.23736/s2724-542x.20.02739-1","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02739-1","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85755006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.23736/s2724-542x.20.02633-6
M. Fioranelli, A. Sepehri, M. Roccia, L. Cota, Chiara Rossi, A. Beesham, T. Lotti
{"title":"The role of brain-spinal cord-heart circuit and its dermatologic antenna in imaging","authors":"M. Fioranelli, A. Sepehri, M. Roccia, L. Cota, Chiara Rossi, A. Beesham, T. Lotti","doi":"10.23736/s2724-542x.20.02633-6","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02633-6","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86178673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.23736/S2724-542X.21.02742-7
S. Satapathy, R. Sahoo, K. P. Pattnaik, L. Panigrahi, S. Mallick
The global pandemic of COVID-19 is progressing rapidly across the world and declared as health emergency. The novel Coronavirus can cause severe lower respiratory tract infections primarily in geriatric, immunocompromised persons, infants and patients with comorbidities, or genetic disorders. Few Emergency Use Authorizations (EAUs) have been granted by FDA and other regulatory bodies with an aim to repurpose the existing approved medicines to fight the disease, and till date no specific treatment methodologies or preventive measures are available. At present, numerous medications which are already approved for other therapeutic indications, as well as the new medications, are undergoing clinical trials for the evaluation of safety and efficacy against COVID-19 infection. These therapeutic ranges include antimalarial, antiviral, steroids, convalescent plasma containing antibodies, and immune modulators, etc. Nevertheless, the primary focus is on preventive care and currently more than hundred potential vaccine candidates are under development by leading biotech companies across the globe which are at different phases of clinical development. Lipid based mRNA delivery, DNA delivery and mAbs are the most advanced technologies being embraced besides whole-virion inactivated vaccine, attenuated live vaccine, non-replicating viral vector-based vaccine, protein single unit vaccine and multiunit vaccine. This review focuses on the current progress in drug delivery systems of COVID-19 vaccine across industries, academics, and government funded research institutes with a special focus on the synthetic mRNA-based lipid nanoparticle (LNP).
{"title":"Developmental biology of Corona vaccine: lipid nanoparticle mRNA-encapsulation, a safe approach","authors":"S. Satapathy, R. Sahoo, K. P. Pattnaik, L. Panigrahi, S. Mallick","doi":"10.23736/S2724-542X.21.02742-7","DOIUrl":"https://doi.org/10.23736/S2724-542X.21.02742-7","url":null,"abstract":"The global pandemic of COVID-19 is progressing rapidly across the world and declared as health emergency. The novel Coronavirus can cause severe lower respiratory tract infections primarily in geriatric, immunocompromised persons, infants and patients with comorbidities, or genetic disorders. Few Emergency Use Authorizations (EAUs) have been granted by FDA and other regulatory bodies with an aim to repurpose the existing approved medicines to fight the disease, and till date no specific treatment methodologies or preventive measures are available. At present, numerous medications which are already approved for other therapeutic indications, as well as the new medications, are undergoing clinical trials for the evaluation of safety and efficacy against COVID-19 infection. These therapeutic ranges include antimalarial, antiviral, steroids, convalescent plasma containing antibodies, and immune modulators, etc. Nevertheless, the primary focus is on preventive care and currently more than hundred potential vaccine candidates are under development by leading biotech companies across the globe which are at different phases of clinical development. Lipid based mRNA delivery, DNA delivery and mAbs are the most advanced technologies being embraced besides whole-virion inactivated vaccine, attenuated live vaccine, non-replicating viral vector-based vaccine, protein single unit vaccine and multiunit vaccine. This review focuses on the current progress in drug delivery systems of COVID-19 vaccine across industries, academics, and government funded research institutes with a special focus on the synthetic mRNA-based lipid nanoparticle (LNP).","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85345655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.23736/s2724-542x.20.02645-2
Hanie Fooladi, Ali Ghanbariasad, Neda Sepahi, A. Taghinezhad, S. Tahmasebi, A. Amiri, H. Mirzaei, Barasa Sahebnazar
{"title":"Multiple biomarker panel for the detection of circulating tumor cells in peripheral blood of breast cancer patients for early detection using the real-time reverse transcription-polymerase chain reaction","authors":"Hanie Fooladi, Ali Ghanbariasad, Neda Sepahi, A. Taghinezhad, S. Tahmasebi, A. Amiri, H. Mirzaei, Barasa Sahebnazar","doi":"10.23736/s2724-542x.20.02645-2","DOIUrl":"https://doi.org/10.23736/s2724-542x.20.02645-2","url":null,"abstract":"","PeriodicalId":29824,"journal":{"name":"Minerva Biotechnology and Biomolecular Research","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80002552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：