Objective: To analyze the therapeutic effect of costochondral graft (CCG) in constructing nasal tip cartilage composite for rhinoplasty. Methods: 84 rhinoplasty patients who were admitted to the hospital between September 2021 and September 2023 were selected and randomly grouped into a study group and a reference group of 42 cases each. The study group was prepared with CCG to construct a nasal tip cartilage composite and the reference group was filled with silicone material to compare the effectiveness of plastic surgery. Results: The plastic effect scores and the perioperative indexes of the study group were all higher than those of the reference group (P < 0.05). Before treatment, there was no difference in the nose-shaping indexes between both groups (P > 0.05). After treatment, the nasal plasticity indexes of the study group were all better than those of the reference group (P < 0.05). The complication rate of the study group was lower than that of the reference group (P < 0.05). Conclusion: The preparation of nasal tip cartilage composite using CCG improved the therapeutic effect of rhinoplasty, improved the perioperative indexes and nasal contouring indexes, and had fewer complications.
{"title":"Analysis of the Effect and Complication of Costochondral Graft in Constructing Nasal Tip Cartilage Composite for Rhinoplasty","authors":"Guanghui Wang","doi":"10.26689/dh.v2i2.7390","DOIUrl":"https://doi.org/10.26689/dh.v2i2.7390","url":null,"abstract":"Objective: To analyze the therapeutic effect of costochondral graft (CCG) in constructing nasal tip cartilage composite for rhinoplasty. Methods: 84 rhinoplasty patients who were admitted to the hospital between September 2021 and September 2023 were selected and randomly grouped into a study group and a reference group of 42 cases each. The study group was prepared with CCG to construct a nasal tip cartilage composite and the reference group was filled with silicone material to compare the effectiveness of plastic surgery. Results: The plastic effect scores and the perioperative indexes of the study group were all higher than those of the reference group (P < 0.05). Before treatment, there was no difference in the nose-shaping indexes between both groups (P > 0.05). After treatment, the nasal plasticity indexes of the study group were all better than those of the reference group (P < 0.05). The complication rate of the study group was lower than that of the reference group (P < 0.05). Conclusion: The preparation of nasal tip cartilage composite using CCG improved the therapeutic effect of rhinoplasty, improved the perioperative indexes and nasal contouring indexes, and had fewer complications.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":" 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141826703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To investigate and analyze the clinical effect of treating patients with chronic urticaria with Yu Ping Feng San combined with olopatadine. Methods: The study period was from January 2023 to January 2024, 46 patients diagnosed with chronic urticaria were extracted as assessment samples, which were randomly divided into an observation group (n = 23) and a control group (n = 23) by using the method of medical record number random drawing. The treatment program for patients in the control group was olopatadine, and the treatment program for patients in the observation group was Yu Ping Feng San combined with olopatadine. The TCM symptom scores, urticaria activity scores (UAS7), itching VAS scores, clinical efficiency, recurrence rate, and incidence of adverse reactions between the two groups were compared. Results: The TCM symptom scores of the observation group were lower than those of the control group after treatment (P < 0.05); the UAS7 score and itching VAS score of the observation group were lower than those of the control group after treatment (P < 0.05); the clinical effective rate of the observation group was higher than that of the control group after treatment, and the recurrence rate was lower than that of the control group (P < 0.05); the comparison of the incidence rates of adverse reactions between the two groups did not show any significant difference (P < 0.05). Conclusion: The treatment effect of patients with chronic urticaria using Yu Ping Feng San combined with olopatadine is remarkable. This combined treatment can relieve the symptoms of Chinese medicine, control the progression of the disease, and reduce the degree of itching, with a lower recurrence rate and higher safety of the medication, which is suitable for popularization and application in healthcare institutions.
{"title":"Clinical Observation on the Combination of Yu Ping Feng San and Olopatadine in the Treatment of Chronic Urticaria","authors":"Feng Jiang","doi":"10.26689/dh.v2i2.7396","DOIUrl":"https://doi.org/10.26689/dh.v2i2.7396","url":null,"abstract":"Objective: To investigate and analyze the clinical effect of treating patients with chronic urticaria with Yu Ping Feng San combined with olopatadine. Methods: The study period was from January 2023 to January 2024, 46 patients diagnosed with chronic urticaria were extracted as assessment samples, which were randomly divided into an observation group (n = 23) and a control group (n = 23) by using the method of medical record number random drawing. The treatment program for patients in the control group was olopatadine, and the treatment program for patients in the observation group was Yu Ping Feng San combined with olopatadine. The TCM symptom scores, urticaria activity scores (UAS7), itching VAS scores, clinical efficiency, recurrence rate, and incidence of adverse reactions between the two groups were compared. Results: The TCM symptom scores of the observation group were lower than those of the control group after treatment (P < 0.05); the UAS7 score and itching VAS score of the observation group were lower than those of the control group after treatment (P < 0.05); the clinical effective rate of the observation group was higher than that of the control group after treatment, and the recurrence rate was lower than that of the control group (P < 0.05); the comparison of the incidence rates of adverse reactions between the two groups did not show any significant difference (P < 0.05). Conclusion: The treatment effect of patients with chronic urticaria using Yu Ping Feng San combined with olopatadine is remarkable. This combined treatment can relieve the symptoms of Chinese medicine, control the progression of the disease, and reduce the degree of itching, with a lower recurrence rate and higher safety of the medication, which is suitable for popularization and application in healthcare institutions.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":" 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141825561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To analyze the application value and complication rate of hyaluronic acid and silicone gel prosthesis in cosmetic rhinoplasty. Methods: 60 patients who underwent cosmetic rhinoplasty in this clinic from March 2022 to March 2023 were selected as research subjects and divided into the hyaluronic acid group and the silicone group by single and double-digit lottery method, with 30 cases in each group. Hyaluronic acid material was used for rhinoplasty in the hyaluronic acid group, and silicone gel material was used for rhinoplasty in the silicone group. The two groups were compared in terms of postoperative complications, improvement rate of nasal shape, satisfaction of firmness, evaluation of surgical satisfaction, and life situation. Results: The incidence of postoperative complications was lower in the hyaluronic acid group than in the silicone group (χ2 = 4.320, P < 0.05); after nasal shape repair, the rate of nasal shape improvement was better in the hyaluronic acid group (29/96.67%) than in the silicone group (24/80.00%) (χ2 = 4.043, P < 0.05); the evaluation of satisfaction with the postoperative firmness of the nasal shape suggested that patients in the hyaluronic acid group (28/93.33%) had a better firmness than patients in the silicone group (22/80.00%) (χ2 = 4.320, P < 0.05); the evaluation of satisfaction with the surgery in the hyaluronic acid group was higher than that in the silicone group (P < 0.05); compared with the preoperative period, the life situation of both groups improved after the surgery, and the scores of the hyaluronic acid group were better than those of the silicone group (both P < 0.001). Conclusion: The application of hyaluronic acid in cosmetic rhinoplasty achieved high clinical value and safety, and this method is recommended to be widely used.
{"title":"Analysis of the Application Value and Complication Rate of Hyaluronic Acid and Silicone Gel Prosthesis in Cosmetic Rhinoplasty","authors":"Kai Zhu","doi":"10.26689/dh.v2i2.5842","DOIUrl":"https://doi.org/10.26689/dh.v2i2.5842","url":null,"abstract":"Objective: To analyze the application value and complication rate of hyaluronic acid and silicone gel prosthesis in cosmetic rhinoplasty. Methods: 60 patients who underwent cosmetic rhinoplasty in this clinic from March 2022 to March 2023 were selected as research subjects and divided into the hyaluronic acid group and the silicone group by single and double-digit lottery method, with 30 cases in each group. Hyaluronic acid material was used for rhinoplasty in the hyaluronic acid group, and silicone gel material was used for rhinoplasty in the silicone group. The two groups were compared in terms of postoperative complications, improvement rate of nasal shape, satisfaction of firmness, evaluation of surgical satisfaction, and life situation. Results: The incidence of postoperative complications was lower in the hyaluronic acid group than in the silicone group (χ2 = 4.320, P < 0.05); after nasal shape repair, the rate of nasal shape improvement was better in the hyaluronic acid group (29/96.67%) than in the silicone group (24/80.00%) (χ2 = 4.043, P < 0.05); the evaluation of satisfaction with the postoperative firmness of the nasal shape suggested that patients in the hyaluronic acid group (28/93.33%) had a better firmness than patients in the silicone group (22/80.00%) (χ2 = 4.320, P < 0.05); the evaluation of satisfaction with the surgery in the hyaluronic acid group was higher than that in the silicone group (P < 0.05); compared with the preoperative period, the life situation of both groups improved after the surgery, and the scores of the hyaluronic acid group were better than those of the silicone group (both P < 0.001). Conclusion: The application of hyaluronic acid in cosmetic rhinoplasty achieved high clinical value and safety, and this method is recommended to be widely used.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":" 67","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141826912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To investigate the relationship between dermoscopic vascular pattern and laser efficacy in children with port wine stains. Methods: From January 2023 to December 2023, 43 children aged 3 to 18 years old with port wine stains in our hospital were selected. The Optimex dermoscopy (American Cynosure Company, Model: M393) was used to observe the vascular pattern and clinical efficacy. Results: There were 14 cases (31.11%) of linear blood vessels, 10 cases (22.22%) of dotted blood vessels, eight cases (17.78%) of reticular blood vessels, seven cases (15.56%) of short rod-shaped blood vessels, three cases (6.67%) of mixed-type blood vessels, and three cases (6.67%) of uniform red background pattern. According to the results of dermoscopy, the effective rates of six types of blood vessels, linear blood vessels, dotted blood vessels, reticular blood vessels, short rod-shaped blood vessels, mixed-type blood vessels, and uniform red background pattern were 71.43%, 100%, 62.50%, 100%, 66.67%, and 33.33%, respectively. The difference was statistically significant (P < 0.05). Conclusion: The treatment efficacy of pulsed dye laser on port wine stains varies with different vascular patterns, and the effects on dotted, short rod-shaped, and linear blood vessels are better.
{"title":"Relationship Between Dermoscopic Vascular Pattern and Laser Efficacy in Children with Port Wine Stains","authors":"Ruijue Li","doi":"10.26689/dh.v2i2.7395","DOIUrl":"https://doi.org/10.26689/dh.v2i2.7395","url":null,"abstract":"Objective: To investigate the relationship between dermoscopic vascular pattern and laser efficacy in children with port wine stains. Methods: From January 2023 to December 2023, 43 children aged 3 to 18 years old with port wine stains in our hospital were selected. The Optimex dermoscopy (American Cynosure Company, Model: M393) was used to observe the vascular pattern and clinical efficacy. Results: There were 14 cases (31.11%) of linear blood vessels, 10 cases (22.22%) of dotted blood vessels, eight cases (17.78%) of reticular blood vessels, seven cases (15.56%) of short rod-shaped blood vessels, three cases (6.67%) of mixed-type blood vessels, and three cases (6.67%) of uniform red background pattern. According to the results of dermoscopy, the effective rates of six types of blood vessels, linear blood vessels, dotted blood vessels, reticular blood vessels, short rod-shaped blood vessels, mixed-type blood vessels, and uniform red background pattern were 71.43%, 100%, 62.50%, 100%, 66.67%, and 33.33%, respectively. The difference was statistically significant (P < 0.05). Conclusion: The treatment efficacy of pulsed dye laser on port wine stains varies with different vascular patterns, and the effects on dotted, short rod-shaped, and linear blood vessels are better.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuanyang Shi, Hua Zhang, Yinuo Liu, W. Fang, Ying Xia, Jin Zhao, Gaoling Zhao, Chunquan Sheng, Qingjie Zhao, Yongsheng He, Amanda Juan Chen, Wanqing Liao, Keya Cai, Bo Pan, Weihua Pan
Cryptococcus neoformans can cause detrimental cryptococcosis and other severe complications, especially in immunocompromised populations. Disseminated cryptococcosis in organ transplantation patients is extremely rare and often involves lungs, brains, skin, nails, and other organs. In this paper, we report a rare disseminated cryptococcosis case involving skin and lung that presented with recurrent dark brown abscesses and nodules in an immunocompromised female after kidney transplantation. The K-Set detection result of Cryptococcus capsular polysaccharide in serum is positive. The identification of pus culture by Autof MS 1000 indicates that the patient was infected with Cryptococcus neoformans var. grubii. In addition to treatment using liposomal amphotericin B, fluorocytosine, and fluconazole, local extraction of pus and simultaneous injection of liposomal amphotericin B into skin lesions were performed. This comprehensive treatment method proved effective, as the patient recovered from fever and skin symptoms. The innovative treatment may contribute to helping more disseminated cryptococcosis patients.
新生隐球菌可引起有害的隐球菌病和其他严重并发症，尤其是在免疫力低下的人群中。器官移植患者中的播散性隐球菌病极为罕见，通常累及肺、脑、皮肤、指甲和其他器官。本文报告了一例罕见的涉及皮肤和肺部的播散性隐球菌病病例，患者为一名肾移植后免疫力低下的女性，表现为反复发作的深褐色脓肿和结节。血清中隐球菌荚膜多糖的 K-Set 检测结果呈阳性。用 Autof MS 1000 进行的脓培养鉴定表明，患者感染的是新型隐球菌变种 grubii。除了使用两性霉素 B 脂质体、氟胞嘧啶和氟康唑进行治疗外，还在局部抽取脓液，同时向皮损处注射两性霉素 B 脂质体。事实证明，这种综合治疗方法非常有效，患者的发烧和皮肤症状均已痊愈。这种创新的治疗方法可能有助于帮助更多的播散性隐球菌病患者。
{"title":"Disseminated Cryptococcosis Involving Skin and Lung in an Immunocompromised Patient After Kidney Transplantation: A Case Report","authors":"Yuanyang Shi, Hua Zhang, Yinuo Liu, W. Fang, Ying Xia, Jin Zhao, Gaoling Zhao, Chunquan Sheng, Qingjie Zhao, Yongsheng He, Amanda Juan Chen, Wanqing Liao, Keya Cai, Bo Pan, Weihua Pan","doi":"10.26689/dh.v1i3.5851","DOIUrl":"https://doi.org/10.26689/dh.v1i3.5851","url":null,"abstract":"Cryptococcus neoformans can cause detrimental cryptococcosis and other severe complications, especially in immunocompromised populations. Disseminated cryptococcosis in organ transplantation patients is extremely rare and often involves lungs, brains, skin, nails, and other organs. In this paper, we report a rare disseminated cryptococcosis case involving skin and lung that presented with recurrent dark brown abscesses and nodules in an immunocompromised female after kidney transplantation. The K-Set detection result of Cryptococcus capsular polysaccharide in serum is positive. The identification of pus culture by Autof MS 1000 indicates that the patient was infected with Cryptococcus neoformans var. grubii. In addition to treatment using liposomal amphotericin B, fluorocytosine, and fluconazole, local extraction of pus and simultaneous injection of liposomal amphotericin B into skin lesions were performed. This comprehensive treatment method proved effective, as the patient recovered from fever and skin symptoms. The innovative treatment may contribute to helping more disseminated cryptococcosis patients.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":"6 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139156485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Charry Anzola, I. Cuellar, Tatiana Valeria Camayo, Maria Daniela Polania
Lichen myxedema (LM) represents a group of rare skin diseases, which falls under chronic mucinoses. LM, previously described as localized scleromyxedema, however, is not associated with systemic involvement. Among the subtypes, atypical LM is rare, with few reported cases associated with multiple myeloma (MM). We present a case of MM, positive for lambda chains, with acute-onset clinical symptoms, and diagnosed with atypical LM. The patient was managed with topical corticosteroid with improvement of lesions after one month of treatment.
{"title":"Atypical Lichen Myxedematosus Associated with Multiple Myeloma","authors":"Laura Charry Anzola, I. Cuellar, Tatiana Valeria Camayo, Maria Daniela Polania","doi":"10.26689/dh.v1i1.4994","DOIUrl":"https://doi.org/10.26689/dh.v1i1.4994","url":null,"abstract":"Lichen myxedema (LM) represents a group of rare skin diseases, which falls under chronic mucinoses. LM, previously described as localized scleromyxedema, however, is not associated with systemic involvement. Among the subtypes, atypical LM is rare, with few reported cases associated with multiple myeloma (MM). We present a case of MM, positive for lambda chains, with acute-onset clinical symptoms, and diagnosed with atypical LM. The patient was managed with topical corticosteroid with improvement of lesions after one month of treatment.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125959411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Atopic dermatitis is a chronic, inflammatory, and pruritic dermatosis of high prevalence, especially in childhood. a relevant public health issue. Atopic dermatitis is associated with several factors, including genetic, psychological, infectious, food, and environmental, and may be associated with other manifestations of atopy, such as asthma and rhinitis. Objective: To determine the epidemiological profile and the prevalence of personal and family history of allergy in children with atopic dermatitis at a referral service, comparing it to existing literature. Methods: We conducted a cross-sectional and descriptive hospital-based study involving children of both genders under 18 years with clinical diagnosis of atopic dermatitis (Hanifin and Rajka criteria) seen at the Pediatric Dermatology Outpatient Clinic of Hospital Municipal Universitário de Taubaté (HMUT), SP-Brazil, from October 2018 to April 2019. Epidemiological data and data related to personal and family history of allergies were collected from the medical records. Microsoft Excel 2019 was used for compilation and data analysis. Results: Of the 440 consultations in that period, 35 (7.9%) were for atopic dermatitis, of which 23 of them were females (65.7%) and 15 were phototype IV (42.9%); their mean age was 7.7 (standard deviation = 4.3), and the duration of disease ranged from 2 months to 14 years (mean 5.3 years; standard deviation = 4.3). Among the 35 patients, 31 (88.6%) manifested the condition by the fifth year of life. Personal history of allergies was observed in 27 individuals (77.1%), with a predominance of allergic rhinitis and in older age groups. Conclusion: This study, as a pioneer in the region, contributes to the epidemiological profile of patients with atopic dermatitis from the Pediatric Dermatology Outpatient Clinic of HMUT, revealing an early onset and a higher prevalence in females and individuals with higher phototypes. In addition, this study also demonstrated the prevalence of personal and family history of allergies in these patients, consistent with literature.
背景:特应性皮炎是一种慢性、炎症性、瘙痒性皮肤病，发病率高，尤其在儿童中。一个相关的公共卫生问题。特应性皮炎与多种因素有关，包括遗传、心理、感染、食物和环境，并可能与其他特应性表现有关，如哮喘和鼻炎。目的:了解转诊儿童特应性皮炎患者的流行病学概况和个人及家族史的流行情况，并与现有文献进行比较。方法:我们进行了一项以医院为基础的横断面和描述性研究，涉及2018年10月至2019年4月在巴西市Universitário de taubat医院(HMUT)儿科皮肤科门诊就诊的18岁以下临床诊断为特应性皮炎(Hanifin和Rajka标准)的男女儿童。从医疗记录中收集流行病学资料以及与个人和家庭过敏史相关的资料。使用Microsoft Excel 2019进行编制和数据分析。结果:440例患者中，特应性皮炎35例(7.9%)，其中女性23例(65.7%)，光型IV型15例(42.9%);平均年龄7.7岁(标准差= 4.3)，病程2个月~ 14年(平均5.3年;标准差= 4.3)。35例患者中，31例(88.6%)在5岁时出现症状。27人(77.1%)有个人过敏史，以变应性鼻炎为主，年龄较大。结论:本研究作为该地区的先驱，有助于了解HMUT儿科皮肤科门诊特应性皮炎患者的流行病学概况，揭示了女性和高光型个体的早发性和高患病率。此外，本研究还证明了这些患者的个人和家族过敏史的普遍性，与文献一致。
{"title":"Epidemiological Profile and Associated Allergic Conditions of Atopic Dermatitis: Data from a Referral Service in Southeastern Brazil","authors":"C. Pereira, F. R. Ferreira","doi":"10.26689/dh.v1i1.4993","DOIUrl":"https://doi.org/10.26689/dh.v1i1.4993","url":null,"abstract":"Background: Atopic dermatitis is a chronic, inflammatory, and pruritic dermatosis of high prevalence, especially in childhood. a relevant public health issue. Atopic dermatitis is associated with several factors, including genetic, psychological, infectious, food, and environmental, and may be associated with other manifestations of atopy, such as asthma and rhinitis. Objective: To determine the epidemiological profile and the prevalence of personal and family history of allergy in children with atopic dermatitis at a referral service, comparing it to existing literature. Methods: We conducted a cross-sectional and descriptive hospital-based study involving children of both genders under 18 years with clinical diagnosis of atopic dermatitis (Hanifin and Rajka criteria) seen at the Pediatric Dermatology Outpatient Clinic of Hospital Municipal Universitário de Taubaté (HMUT), SP-Brazil, from October 2018 to April 2019. Epidemiological data and data related to personal and family history of allergies were collected from the medical records. Microsoft Excel 2019 was used for compilation and data analysis. Results: Of the 440 consultations in that period, 35 (7.9%) were for atopic dermatitis, of which 23 of them were females (65.7%) and 15 were phototype IV (42.9%); their mean age was 7.7 (standard deviation = 4.3), and the duration of disease ranged from 2 months to 14 years (mean 5.3 years; standard deviation = 4.3). Among the 35 patients, 31 (88.6%) manifested the condition by the fifth year of life. Personal history of allergies was observed in 27 individuals (77.1%), with a predominance of allergic rhinitis and in older age groups. Conclusion: This study, as a pioneer in the region, contributes to the epidemiological profile of patients with atopic dermatitis from the Pediatric Dermatology Outpatient Clinic of HMUT, revealing an early onset and a higher prevalence in females and individuals with higher phototypes. In addition, this study also demonstrated the prevalence of personal and family history of allergies in these patients, consistent with literature.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126841226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omalizumab (Xolair®) was approved for the treatment of chronic idiopathic urticaria in 2017. Furthermore, consistent with international guidelines published in 2018, the Urticaria Clinical Practice Guidelines by the Japanese Dermatological Association provide detailed instructions for the use of omalizumab. However, there are no reports summarizing the efficacy of omalizumab in chronic idiopathic urticaria in Japan. The subjects of our study were 105 patients treated with omalizumab 300 mg/month for chronic idiopathic urticaria at Tokyo Medical University Hospital from June 2017 to March 2021, inclusive of 23 male and 82 female patients, with a mean age of 45.4 ± 16.0 and disease duration of 46.9 ± 99.4 months. Three months after treatment, omalizumab was discontinued in 63 patients with a Urticaria Control Test score of 16. The mean number of dose completions was 6.4 ± 4.1. There were nine cases of relapse in which seven of the nine cases discontinued omalizumab within six doses. Most of the relapsed cases improved with re-administration of omalizumab, but it was again discontinued in five cases. Omalizumab has lesser side effects than steroids and cyclosporine, and the criteria for its use were revised in 2018, requiring an allergist or dermatologist to be available to treat adverse events such as asthma and anaphylaxis at the facility or in collaboration with neighboring medical institutions. Omalizumab can also be used in dermatology clinics. The drug is an effective treatment for severe chronic idiopathic urticaria and is anticipated to be used by more dermatologists.
{"title":"A Study of 105 Patients Treated with Omalizumab for Chronic Idiopathic Urticaria","authors":"Tomonobu Ito, Y. Okubo, K. Harada","doi":"10.26689/dh.v1i1.4997","DOIUrl":"https://doi.org/10.26689/dh.v1i1.4997","url":null,"abstract":"Omalizumab (Xolair®) was approved for the treatment of chronic idiopathic urticaria in 2017. Furthermore, consistent with international guidelines published in 2018, the Urticaria Clinical Practice Guidelines by the Japanese Dermatological Association provide detailed instructions for the use of omalizumab. However, there are no reports summarizing the efficacy of omalizumab in chronic idiopathic urticaria in Japan. The subjects of our study were 105 patients treated with omalizumab 300 mg/month for chronic idiopathic urticaria at Tokyo Medical University Hospital from June 2017 to March 2021, inclusive of 23 male and 82 female patients, with a mean age of 45.4 ± 16.0 and disease duration of 46.9 ± 99.4 months. Three months after treatment, omalizumab was discontinued in 63 patients with a Urticaria Control Test score of 16. The mean number of dose completions was 6.4 ± 4.1. There were nine cases of relapse in which seven of the nine cases discontinued omalizumab within six doses. Most of the relapsed cases improved with re-administration of omalizumab, but it was again discontinued in five cases. Omalizumab has lesser side effects than steroids and cyclosporine, and the criteria for its use were revised in 2018, requiring an allergist or dermatologist to be available to treat adverse events such as asthma and anaphylaxis at the facility or in collaboration with neighboring medical institutions. Omalizumab can also be used in dermatology clinics. The drug is an effective treatment for severe chronic idiopathic urticaria and is anticipated to be used by more dermatologists.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121772486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Celia, C. Giménez, A. Miranda, E. Haas, M. López, C. Civale
Malignant fibrous histiocytoma is the most common soft tissue sarcoma in adults but is rare as a primary cutaneous tumor. It has a male predilection with a peak incidence between the fifth and sixth decades of life. Malignant fibrous histiocytoma predominantly occurs in the extremities. We report a case of malignant fibrous histiocytoma presenting in the hallux of the right foot.
{"title":"Malignant Fibrous Histiocytoma","authors":"D. Celia, C. Giménez, A. Miranda, E. Haas, M. López, C. Civale","doi":"10.26689/dh.v1i1.4992","DOIUrl":"https://doi.org/10.26689/dh.v1i1.4992","url":null,"abstract":"Malignant fibrous histiocytoma is the most common soft tissue sarcoma in adults but is rare as a primary cutaneous tumor. It has a male predilection with a peak incidence between the fifth and sixth decades of life. Malignant fibrous histiocytoma predominantly occurs in the extremities. We report a case of malignant fibrous histiocytoma presenting in the hallux of the right foot.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124320149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Guindo, A. Keita, M. Diakité, F. Haidara, K. Tall, Y. Fofana, L. Cissé, B. Traoré, M. Sissoko, A. Traore, Y. Karabinta, M. Gassama, H. Thiam, A-A Dicko, O. Faye
Background: Psoriasis is a chronic recurrent inflammatory dermatosis occurring in genetically predisposed individuals. Its dramatic nature of the lesions, successive flare-ups, and skin discomfort may affect the quality of life of patients and result in a depressive tendency. Objective: To assess the impact of psoriasis on the quality of life of patients and the relationship between disease severity and quality of life. Methods: A descriptive cross-sectional study was carried out in Bamako from September 3, 2018 to August 30, 2019. The Dermatology Life Quality Index (DLQI) and Psoriasis Area Severity Index (PASI) were used to assess quality of life and factors of disease severity. Inclusion was based on clinical and histopathologic criteria. Questionable cases were excluded from the study. Results: A total of 106 cases of psoriasis were identified out of 24,000 consultations, i.e., a hospital frequency of 0.44%. Of these cases, 54 were included. Males accounted for 70% of the cases, and the average age was 37. The distribution of the social repercussions of the disease was as follows: disability (68.52%), non-participation in ceremonies (20.37%), stigmatization (18.52%), isolation (12.96%), work stoppage (11.11%), and non-sharing of meals (9.26%). However, the reception by caregivers was satisfactory in 96.30% of cases, and 85% of patients scored ≤ 10 on DLQI, suggesting that they had good quality of life. Among the patients with psoriasis, 35.04%, 12.96%, and 50.00% had mild, moderate, and severe disease, respectively. Conclusion: Quality of life is multifactorial and has no direct association with the severity of psoriasis. Dermatologists must take into account the dimensions of symptoms and psychological state when managing patients with psoriasis.
{"title":"Quality of Life of Patients with Psoriasis: A Study of 54 Patients in Bamako","authors":"B. Guindo, A. Keita, M. Diakité, F. Haidara, K. Tall, Y. Fofana, L. Cissé, B. Traoré, M. Sissoko, A. Traore, Y. Karabinta, M. Gassama, H. Thiam, A-A Dicko, O. Faye","doi":"10.26689/dh.v1i1.4995","DOIUrl":"https://doi.org/10.26689/dh.v1i1.4995","url":null,"abstract":"Background: Psoriasis is a chronic recurrent inflammatory dermatosis occurring in genetically predisposed individuals. Its dramatic nature of the lesions, successive flare-ups, and skin discomfort may affect the quality of life of patients and result in a depressive tendency. Objective: To assess the impact of psoriasis on the quality of life of patients and the relationship between disease severity and quality of life. Methods: A descriptive cross-sectional study was carried out in Bamako from September 3, 2018 to August 30, 2019. The Dermatology Life Quality Index (DLQI) and Psoriasis Area Severity Index (PASI) were used to assess quality of life and factors of disease severity. Inclusion was based on clinical and histopathologic criteria. Questionable cases were excluded from the study. Results: A total of 106 cases of psoriasis were identified out of 24,000 consultations, i.e., a hospital frequency of 0.44%. Of these cases, 54 were included. Males accounted for 70% of the cases, and the average age was 37. The distribution of the social repercussions of the disease was as follows: disability (68.52%), non-participation in ceremonies (20.37%), stigmatization (18.52%), isolation (12.96%), work stoppage (11.11%), and non-sharing of meals (9.26%). However, the reception by caregivers was satisfactory in 96.30% of cases, and 85% of patients scored ≤ 10 on DLQI, suggesting that they had good quality of life. Among the patients with psoriasis, 35.04%, 12.96%, and 50.00% had mild, moderate, and severe disease, respectively. Conclusion: Quality of life is multifactorial and has no direct association with the severity of psoriasis. Dermatologists must take into account the dimensions of symptoms and psychological state when managing patients with psoriasis.","PeriodicalId":299678,"journal":{"name":"Dermatological Health","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132535850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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