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Comparison of Blood Homocysteine Levels between Women with Recurrent Pregnancy Loss and Women with Normal Fertility 复发性流产妇女与正常生育妇女血液同型半胱氨酸水平的比较
Pub Date : 2023-02-02 DOI: 10.3329/jemc.v11i1.63168
Mossammat Nigar Sultana, S. Rahman, Julia Akhtar Nira, P. Fatima
Background: Recurrent early pregnancy loss is a common but frequently unexplained obstetric problem. As it happens in early weeks of pregnancy, abnormal vasculogenesis and disordered cell multiplication are possible causes. Hyperhomocysteinemia is associated with both these pathological processes.Objective: To assess the association between hyperhomocysteinemia and recurrent pregnancy loss.Materials and Methods: This case-control observational study was conducted in the Department of Gynaecology and Obstetrics of Bangabandhu Sheikh Mujib Medical University, Dhaka during January to December 2015. Sixty patients were divided into two groups: 30 with recurrent pregnancy loss (RPL) as cases and 30 normal healthy mothers as controls.Results: All the subjects were matched in terms of age (p = 0.504). All were within normal BMI range (19.5 to 25 kg/square meter). Subjects in both groups were comparable in height, weight and BMI. 33.3% women of control group were in the low income stratum (monthly income 20000 taka or less) compared to50% of the RPL group. Control group had an equal mix of educational level from below Secondary School to Post-Graduates whereas there were fewer Post Graduate patients (3.3%) in the RPL group compared to control group (23.3%). The frequency of hyperhomocysteinemia (>15 micromoles/L) was significantly higher in cases compared to controls (46.7 vs.16.7%, p= 0.012). Mean homocysteine level was also significantly higher in cases compared to controls (13.67+/-4.80 vs. 9.87+/-4.84 micromole/L; p= 0.003).Conclusion: This study shows that blood homocysteine level in recurrent pregnancy loss patients is significantly higher compared to normal fertile mothers. There is a strong association between hyperhomocysteinemia and RPL.J Enam Med Col 2021; 11(1): 10-17
背景:复发性早孕损失是一个常见但经常无法解释的产科问题。由于发生在妊娠早期,血管生成异常和细胞增殖紊乱是可能的原因。高同型半胱氨酸血症与这两种病理过程有关。目的:探讨高同型半胱氨酸血症与复发性流产的关系。材料和方法:本病例对照观察性研究于2015年1月至12月在达卡Bangabandhu Sheikh Mujib医科大学妇产科进行。将60例患者分为两组:30例复发性妊娠丢失(RPL)为病例,30例正常健康母亲为对照。结果:所有受试者的年龄匹配(p=0.504)。所有受试人均在正常BMI范围内(19.5至25kg/平方米)。两组受试者的身高、体重和BMI具有可比性。对照组33.3%的女性属于低收入阶层(月收入20000塔卡或以下),而RPL组为50%。对照组从中学以下到研究生的教育水平相同,而RPL组的研究生患者(3.3%)比对照组(23.3%)少。与对照组相比,病例中高同型半胱氨酸血症(>15微摩尔/L)的频率显著更高(46.7%对1.67%,p=0.012)。平均同型半胱氨酸水平也显著更高结论:本研究表明,复发性流产患者的血液同型半胱氨酸水平明显高于正常生育母亲。高同型半胱氨酸血症与RPL之间有很强的相关性。《搪瓷医学杂志》2021;11(1):10-17
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引用次数: 0
Outcome of Acute Kidney Injury (AKI) Patients in the Intensive Care Unit of Enam Medical College & Hospital During the Period of July 2018 to May 2019 2018年7月至2019年5月伊纳姆医学院和医院重症监护病房急性肾损伤(AKI)患者的预后
Pub Date : 2023-02-02 DOI: 10.3329/jemc.v11i1.63170
Easnem Khanam, Shamimur Rahman, A. Islam, Nelufa Tahera Rahman
Background: Acute kidney injury (AKI) is a public health issue associated with multiple clinical conditions which may occur due to slight elevation in serum creatinine to anuric renal failure with electrolytes and acid-base imbalance, chronic kidney diseases, end-stage renal diseases, impaired innate immunity associated with higher infection rate, and increased duration of hospital stay with higher cost. Sometimes severe AKI patients may need intensive care support and renal replacement therapy. Severe sepsis is the most common cause of ICU admission.Materials and Methods: This observational study was conducted during the period of July 2018 to May 2019 in the Department of Anesthesiology and Intensive Care Unit of Enam Medical College & Hospital, Savar Dhaka. A total of 87 AKI patients were selected among which 48 were male and 39 were female. Acute kidney injury was selected with an increase in serum creatinine >0.3 mg /dL within 48 hours or ≥1.5 mg /dL from the base line within prior 7 days or urine volume <0.5mL/kg/hour. The last recorded lowest value or value within 24 hrs before admission was considered as baseline S. creatinine. Staging was done according to the KDIGO classification. Chronic Kidney Diseases (CKD) patients and acute on chronic kidney diseases patients aged <18 years were excluded from our study.Results: Highest age group was between 41 to 60 years. According to KDIGO definition 27.58% fell in stage-I, 39.8% in Stage-II and 33.33% in Stage-III. Hypertension (34.48%) and diabetes (24.18%) were found common co-morbid conditions. The most common indication for admission in ICU was septicemia (21.83%). Other causes include pneumonia and other respiratory illness (18.39%), gynae and obstetrical cases (16.09%) AGE (acute gastroenteritis) 13.79%, poisoning 9.19%, polytrauma 8.0%, cardiac diseases 6.89%, cerebrovascular diseases 3.44%, malignancy 2.29%. Total 62.06% (54) patients needed ionotropic support, 55.17% (48) needed artificial ventilation. 26.4% patients needed renal replacement therapy (8.04% HD, 12.64% SLED, 5.74% CRRT). Finally, 66 (75.86%) patients survived among which 59 (67.81%) recovered completely from AKI, 7 (8.04%) turned into CKD and 21 (24.13%) expired.Conclusion: Early detection and extensive ICU management may lead to full recovery of renal function which ultimately reduces adverse outcomes, renal replacement therapy and AKI-related morbidity and mortality.J Enam Med Col 2021; 11(1): 24-33
背景:急性肾损伤(AKI)是一种与多种临床情况相关的公共卫生问题,可由血清肌酐轻微升高、无尿性肾功能衰竭伴电解质和酸碱失衡、慢性肾脏疾病、终末期肾脏疾病、先天免疫功能受损与较高感染率相关、住院时间延长与较高费用相关。有时严重的AKI患者可能需要重症监护支持和肾脏替代治疗。严重脓毒症是ICU住院最常见的原因。材料与方法:本观察性研究于2018年7月至2019年5月在达卡萨瓦伊纳姆医学院和医院麻醉科和重症监护病房进行。共选取87例AKI患者,其中男性48例,女性39例。急性肾损伤选择48小时内血清肌酐升高0.3 mg /dL或7天内基线升高≥1.5 mg /dL或尿量<0.5mL/kg/小时。最后记录的最低值或入院前24小时内的值被视为基线S.肌酐。根据KDIGO分级进行分期。慢性肾脏疾病(CKD)患者和年龄<18岁的急性慢性肾脏疾病患者被排除在我们的研究之外。结果:41 ~ 60岁年龄组发病率最高。根据KDIGO的定义,27.58%为i期,39.8%为ii期,33.33%为iii期。高血压(34.48%)和糖尿病(24.18%)是常见的合并症。ICU住院最常见的指征是败血症(21.83%)。其他原因包括肺炎及其他呼吸系统疾病(18.39%)、妇产科病例(16.09%)、AGE(急性胃肠炎)13.79%、中毒9.19%、多发伤8.0%、心脏病6.89%、脑血管疾病3.44%、恶性肿瘤2.29%。54例(62.06%)患者需要离子化支持,48例(55.17%)患者需要人工通气。26.4%的患者需要肾脏替代治疗(HD占8.04%,SLED占12.64%,CRRT占5.74%)。最终存活66例(75.86%),其中完全康复59例(67.81%),转为CKD 7例(8.04%),死亡21例(24.13%)。结论:早期发现和广泛的ICU管理可使肾功能完全恢复,最终减少不良后果、肾脏替代治疗和aki相关的发病率和死亡率。中南大学学报(自然科学版);11 (1): 33
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引用次数: 0
College News Vol. 11(1) 大学新闻第11卷(1)
Pub Date : 2023-02-02 DOI: 10.3329/jemc.v11i1.63176
Halima Begum
Abstract not availableJ Enam Med Col 2021; 11(1): 59
摘要不可用J Enam Med Col 2021;11(1):59
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引用次数: 0
Antibiogram of Extended Spectrum Beta-Lactamase and AmpC Beta- Lactamase Producing Escherichia coli among the Patients Attending a Selected Tertiary Health Care Hospital 某三级卫生保健医院就诊患者中产生广谱β-内酰胺酶和AmpCβ-内肽酶大肠杆菌的抗体谱
Pub Date : 2022-05-10 DOI: 10.3329/jemc.v10i3.59360
Lotifur Rahman, Asna Smzh, Md Abdul Aziz
Background: The global emergence and spread of Extended Spectrum Beta-Lactamases (ESBLs) and AmpC beta-lactamases (AmpC) producing Escherichia coli (E. coli) have become a global concern because of inducing resistance toward most of the antimicrobial classes and making the treatment difficult. Hence, this study was aimed to assess the prevalence and antibiotic resistance pattern of ESBL and AmpC beta-lactamases producing E. coli in Bangladesh Institute of Health Sciences (BIHS) General Hospital.Objectives: To assess the prevalence of ESBL +ve and AmpC +ve producing E. coli and to see their antibiotic resistance pattern in BIHS General Hospital.Materials and Methods: A total of 675 samples were subjected to aerobic bacteriologic culture in the department of Microbiology, BIHS General Hospital, Mirpur, Dhaka, during the period of 1st July 2016 to 30th June 2017. Specimens were collected from hospitalized and outdoor patients of different age and sex groups. All the isolates were identified by standard microbiological technique and their antibiotic susceptibility was observed by disk diffusion method. Strict aseptic precautions were taken all through the culture system.Results: Out of 675 specimens, 150 (22.22%) culture yielded growth of E. coli. Among them 47 (31.3%) were ESBL +ve, 27 (18%) were AmpC +ve and 7 (4.7%) were both AmpC +ve and ESBL +ve E. coli.Conclusion: Advance antibiotic resistance surveillance is necessary to guide the appropriate and judicious antibiotic use. The antibiotic should be used after performing culture and sensitivity test to minimize increasing trend of drug resistance.J Enam Med Col 2020; 10(3): 179-185
背景:超广谱β-内酰胺酶(ESBLs)和产AmpCβ-内内酰胺酶的大肠杆菌(E.coli)在全球范围内的出现和传播已成为全球关注的问题,因为它们会诱导对大多数抗菌药物的耐药性,并使治疗变得困难。因此本研究旨在评估孟加拉国卫生科学研究所(BIHS)总医院产ESBL和AmpCβ-内酰胺酶大肠杆菌的患病率和耐药性模式。目的:评估产ESBL+ve和AmpC+ve大肠杆菌的发病率,并了解其在BIHS总医院的耐药性模式。材料和方法:共675份样本于2016年7月1日至2017年6月30日在达卡米尔布尔BIHS综合医院微生物科接受需氧细菌培养。标本采集自不同年龄和性别组的住院和室外患者。所有分离株均采用标准微生物技术进行鉴定,并用纸片扩散法观察其对抗生素的敏感性。整个培养系统都采取了严格的无菌预防措施。结果:在675份标本中,150份(22.22%)培养物产生了大肠杆菌生长。其中ESBL+ve大肠杆菌47株(31.3%),AmpC+ve大肠杆菌27株(18%),AmpC+ve和ESBL+E大肠杆菌7株(4.7%)。结论:加强抗生素耐药性监测是指导合理使用抗生素的必要条件。抗生素应在进行培养和敏感性测试后使用,以尽量减少耐药性的增加趋势。《搪瓷医学杂志》2020;10(3):179-185
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引用次数: 0
Outcome of Temporalis Myofascial Flap as an Interpositional Material in Temporomandibular Joint Ankylosis 颞肌筋膜瓣作为颞下颌关节强直的修复材料
Pub Date : 2022-05-10 DOI: 10.3329/jemc.v10i3.59361
A. Faruq, S. Sultana
Temporomandibular joint ankylosis is a common problem in Bangladesh due to trauma and infection. Diverse interpositional materials have been proposed in this regard with especial advantages and limitation. Interpositional arthroplasty is the best solution. The aim of this review article is to provide a useful clinical update about interpositional arthroplasty in temporomandibular joint ankylosis, its advantages and limitations. For this purpose eighteen articles were selected through searching internet, reviewed and are summarized here. Dental surgeons need proper training for proper diagnosis and adequate treatment. Research in this field will be helpful for both patients and doctors. Temporomandibular joint ankylosis, treatment objectives of TMJ ankylosis and update of temporalis myofascial flap as an interpositional material are described here.J Enam Med Col 2020; 10(3): 186-189
颞下颌关节强直是孟加拉国常见的创伤和感染问题。在这方面,已经提出了各种各样的中介材料,它们具有特殊的优点和局限性。位置间关节成形术是最好的解决方案。这篇综述文章的目的是提供一个有用的临床更新,关节间关节成形术治疗颞下颌关节强直,其优点和局限性。为此,本文通过互联网检索,选取18篇文章进行综述。牙科外科医生需要适当的培训来进行正确的诊断和充分的治疗。这一领域的研究对病人和医生都有帮助。本文介绍颞下颌关节强直、颞下颌关节僵硬的治疗目标以及颞肌筋膜瓣作为一种介入材料的更新。《搪瓷医学杂志》2020;10(3):186-189
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引用次数: 0
Rehabilitation of COVID 19 Patients, a Critically Important Issue COVID 19患者的康复,一个至关重要的问题
Pub Date : 2022-05-10 DOI: 10.3329/jemc.v10i3.59354
M. Rahman
Abstract not availableJ Enam Med Col 2020; 10(3): 136-138
摘要不可用J Enam Med Col 2020;10(3):136-138
{"title":"Rehabilitation of COVID 19 Patients, a Critically Important Issue","authors":"M. Rahman","doi":"10.3329/jemc.v10i3.59354","DOIUrl":"https://doi.org/10.3329/jemc.v10i3.59354","url":null,"abstract":"Abstract not available\u0000J Enam Med Col 2020; 10(3): 136-138","PeriodicalId":30472,"journal":{"name":"Journal of Enam Medical College","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47398269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Children with Behavioral Problem and/or Cognitive Deficit: It’s Correlation with Maternal Employment 有行为问题和/或认知缺陷的儿童:与母亲就业相关
Pub Date : 2022-05-10 DOI: 10.3329/jemc.v10i3.59355
F. Afroze, M. Haque, S. Banu, R. Alam
Background: Hospital records reveal a gradual increase in the number of children with behavioral and cognitive problems. Maternal employment has also been rising steadily. However, little is known about the relationship between maternal employment and child’s behavioral and cognitive problems.Objective: To evaluate the child’s behavioral and cognitive problems and their relationship with maternal employment.Materials and Methods: This cross-sectional analytical study was conducted on 30 children aged 3−8 years, having cognitive and/or behavioral problems who fulfilled the enrollment criteria. Data were analyzed descriptively and Chi-square/Fisher’s exact tests were used wherever appropriate with significance set at p<0.05.Results: Children’s mean age was 5.5±2.0 years (M:F 1.3:1). Of all children, 73.3% were family’s 1st child, 83.3% belonged to nuclear family. Among parents 43% spent quality time with children. Among mothers 40% were service holders and others were housewives. All working mothers were employed before 3rd year of their children. Among working mothers 84% worked 8 hours per day. Externalizing and internalizing behavior problems, non-satisfactory school performance and non-disciplined activities were found higher among working mothers’ children compared to housewife mothers’ children (50.0% vs 38.9%; 16.7% vs 11.1%; 91.7% vs 88.9%; 50.0% vs 44.4%, respectively). In this study >1 behavior problems and delayed cognition were found higher among housewife mothers’ children (33.3% vs. 38.9%; 41.7% vs. 66.7%). In both groups, 83.3% children were not involved in extracurricular activities. Overall, Risk Ratios did not predict any risk of having behavioral problems with mothers’ employment (all p values >0.05).Conclusion: This study demonstrated no significant effect of maternal employment on developing child’s behavioral and cognitive problems. To generalize the findings, large-scale study is recommended.J Enam Med Col 2020; 10(3): 143-152
背景:医院记录显示有行为和认知问题的儿童数量逐渐增加。产妇就业也在稳步上升。然而,关于母亲就业与儿童行为和认知问题之间的关系,人们知之甚少。目的:探讨儿童的行为和认知问题及其与母亲就业的关系。材料和方法:本横断面分析研究对30名符合入组标准的3 - 8岁有认知和/或行为问题的儿童进行研究。对数据进行描述性分析,并酌情使用卡方/Fisher精确检验,显著性集为p1,发现家庭主妇母亲的孩子的行为问题和认知延迟更高(33.3%比38.9%;41.7% vs. 66.7%)。在两组中,83.3%的孩子没有参加课外活动。总体而言,风险比并不能预测母亲就业后出现行为问题的风险(p值均为0.05)。结论:本研究未发现母亲就业对儿童行为和认知问题的发展有显著影响。为了推广研究结果,建议进行大规模的研究。中南大学学报(自然科学版);(3): 143 - 152
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引用次数: 0
Clinical and Genetic Studies of Limb Girdle Muscular Dystrophy: Reports of Two Cases 肢带性肌萎缩症的临床与遗传学研究:附2例报告
Pub Date : 2022-05-10 DOI: 10.3329/jemc.v10i3.59362
R. Islam, K. Fatema, Anjir Anwar, M. Rahman, S. Akhter
Limb girdle muscular dystrophy (LGMD) presents with weakness and wasting of muscles, initially appear at proximal group of pelvic and shoulder girdles and inherited by an autosomal recessive disorder mainly and rarely autosomal dominant trait. We report two young girls of limb girdle muscular dystrophy (LGMD), who presented with gradual onset of weakness in proximal muscle of all four limbs. There was positive family history in one girl. Neurological examination revealed pseudo hypertrophy of both calves, hypotonia in all four limbs, muscle power diminished, more on proximally. All deep tendon reflexes were diminished with planters bilateral flexors. Gower sign was positive and winging of scapula was also present. Electromyography (EMG) showed myopathic pattern. Both had elevated creatinine phosphokinase levels and finally genetic study confirmed the diagnosis.J Enam Med Col 2020; 10(3): 190-194
肢体带状肌营养不良症(LGMD)表现为肌肉无力和萎缩,最初出现在骨盆和肩带近端组,以常染色体隐性遗传为主,很少有常染色体显性遗传。我们报告两名年轻女孩的肢体带状肌营养不良症(LGMD),谁提出了逐渐出现的衰弱近端肌肉的所有四肢。1名女孩有阳性家族史。神经学检查显示双小腿假性肥厚,四肢张力下降,肌肉力量减弱,更近端。植入双侧屈肌后,所有深肌腱反射均减弱。高尔征阳性,肩胛骨也有翅状。肌电图显示肌病型。两人均有肌酐磷酸激酶水平升高,最终基因研究证实了诊断。中南大学学报(自然科学版);(3): 190 - 194
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引用次数: 0
Reviewers in this Issue Vol.10(3) 第10卷(3)期审稿人
Pub Date : 2022-05-10 DOI: 10.3329/jemc.v10i3.59365
E. Chief
Abstract not availableJ Enam Med Col 2020; 10(3): 200
摘要不可用J Enam Med Col 2020;10(3):200
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引用次数: 0
Enhancing Dorsal Spinal Cord Mass in a 50-Year-Old Lady 一名50岁女性脊髓背侧肿块增强
Pub Date : 2022-05-10 DOI: 10.3329/jemc.v10i3.59363
Samar C Sarkar, Mashah Binte Amin
Abstract not availableJ Enam Med Col 2020; 10(3): 195-197
摘要不可用J Enam Med Col 2020;10(3):195-197
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引用次数: 0
期刊
Journal of Enam Medical College
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