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Exploring Patients' Needs and Desires for Quality Prenatal Care in Florida, United States. 探索美国佛罗里达州患者对优质产前护理的需求和愿望。
Pub Date : 2023-01-01 Epub Date: 2023-04-28 DOI: 10.21106/ijma.622
Kimberly Fryer, Chinyere N Reid, Naciely Cabral, Jennifer Marshall, Usha Menon

Background and objective: High-quality prenatal care promotes adequate care throughout pregnancy by increasing patients' desires to return for follow-up visits. Almost 15% of women in the United States receive inadequate prenatal care, with 6% receiving late or no prenatal care. Only 63% of pregnant women in Florida receive adequate prenatal care, and little is known about their perceptions of high-quality prenatal care. Therefore, the objective of this study was to assess women's perceptions of the quality of their prenatal care and to describe their preferences for seeking prenatal care that meets their needs.

Methods: From April to December 2019, a qualitative study was conducted with postpartum women (n = 55) who received no or late prenatal care and delivered in Tampa, Florida, USA. Eligible women completed an open-ended qualitative survey and a semi-structured in-depth interview. The interview contextualized the factors influencing prenatal care quality perceptions. The qualitative data analysis was based on Donabedian's quality of care model.

Results: The qualitative data analysis revealed three key themes about women's perceptions and preferences for prenatal care that meets their needs. First, clinical care processes included provision of health education and medical assessments. Second, structural conditions included language preferences, clinic availability, and the presence of ancillary staff. Finally, interpersonal communication encompassed interactions with providers and continuity of care. Overall, participants desired patient-centered care and care that was informative, tailored to their needs, and worked within the constraints of their daily lives.

Conclusion and global health implications: Women seeking and receiving prenatal care prefer a welcoming, patient-centered health care environment. These findings should prompt health care providers and organizations to improve existing prenatal care models and develop new prenatal care models that provide early, accessible, and high-quality prenatal care to a diverse population of maternity patients.

背景和目的:高质量的产前护理可提高患者复诊的意愿,从而促进整个孕期的充分护理。在美国,近 15%的妇女接受的产前护理不足,6%的妇女接受产前护理较晚或没有接受产前护理。在佛罗里达州,只有 63% 的孕妇接受了适当的产前护理,而她们对高质量产前护理的看法却鲜为人知。因此,本研究旨在评估妇女对产前护理质量的看法,并描述她们在寻求符合自身需求的产前护理时的偏好:从 2019 年 4 月到 12 月,在美国佛罗里达州坦帕市对未接受或延迟接受产前护理并分娩的产后妇女(n = 55)进行了一项定性研究。符合条件的妇女完成了开放式定性调查和半结构化深度访谈。访谈将影响产前护理质量认知的因素背景化。定性数据分析以 Donabedian 的护理质量模型为基础:定性数据分析揭示了妇女对满足其需求的产前护理的看法和偏好的三个关键主题。首先,临床护理过程包括提供健康教育和医疗评估。其次,结构条件包括语言偏好、诊所的可用性和辅助人员的存在。最后,人际沟通包括与医疗服务提供者的互动和护理的连续性。总之,参与者希望获得以患者为中心的护理和信息丰富、符合其需求并能在其日常生活限制范围内工作的护理:寻求和接受产前护理的妇女更喜欢热情、以患者为中心的医疗环境。这些发现应促使医疗服务提供者和机构改进现有的产前护理模式,并开发新的产前护理模式,为不同的孕产妇提供早期、方便和高质量的产前护理。
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引用次数: 0
Housing and Inequalities in US Life Expectancy, Child and Youth Mortality, and All-Cause and Cause-Specific Mortality, 1979-2020: Results from the National Longitudinal Mortality Study and the National Vital Statistics System. 1979-2020 年美国预期寿命、儿童和青少年死亡率以及全因和特定原因死亡率中的住房和不平等现象:全国纵向死亡率研究》和《全国人口动态统计系统》的结果。
Pub Date : 2023-01-01 Epub Date: 2023-12-20 DOI: 10.21106/ijma.653
Gopal K Singh, Hyunjung Lee, Lyoung Hee Kim

Background: Limited research exists on the association between housing, life expectancy, and mortality disparities in the United States (US). Using longitudinal individual-level and pooled county-level mortality data from 1979 to 2020, we examine disparities in life expectancy, child and youth mortality, and all-cause and cause-specific mortality in the US by several housing variables.

Methods: Using the 1979-2011 National Longitudinal Mortality Study (N=1,313,627) and the 2011-2020 linked county-level National Mortality Database and American Community Survey, we analyzed disparities in life expectancy and all-cause and cause-specific disparities by housing tenure, household crowding, and housing stability. Multivariate Cox proportional hazards regression was used to analyze individual-level mortality differentials by housing tenure. Age-adjusted mortality rates and rate ratios were used to analyze area-level disparities in mortality by housing variables.

Results: US homeowners had, on average, a 3.5-year longer life expectancy at birth than renters (74.22 vs. 70.76 years), with advantages in longevity associated with homeownership being greater for males than for females; for American Indians/Alaska Natives, non-Hispanic Whites, and non-Hispanic Blacks than for Asian/Pacific islanders and Hispanics; and for the US-born than for immigrants. Compared with renters, homeowners had 22% lower risks of all-cause mortality, 15% lower child mortality, 17% lower youth mortality, and significantly lower mortality from cardiovascular diseases, all cancers combined, stomach, liver, esophageal and cervical cancer, diabetes, influenza and pneumonia, COPD, cirrhosis, kidney disease, HIV/AIDS, infectious diseases, unintentional injuries, suicide, and homicide.

Conclusion and global health implications: Several aspects of housing are strongly associated with life expectancy, child and youth mortality, and all-cause and cause-specific mortality in the US. Policies that aim to provide well-designed, accessible, and affordable housing to residents of both developed and developing countries are important policy options for addressing one of the most fundamental determinants of health for disadvantaged individuals and communities and for reducing health inequities globally.

背景:关于美国住房、预期寿命和死亡率差异之间关系的研究十分有限。我们利用 1979 年至 2020 年的个人纵向死亡率数据和汇总的县级死亡率数据,通过几个住房变量研究了美国人在预期寿命、儿童和青少年死亡率以及全因和特定原因死亡率方面的差异:利用 1979-2011 年全国纵向死亡率研究(N=1,313,627)以及 2011-2020 年县级全国死亡率数据库和美国社区调查的关联数据,我们按住房保有权、家庭拥挤程度和住房稳定性分析了预期寿命差异以及全因和特定原因死亡率差异。多变量考克斯比例危险回归用于分析按住房保有权划分的个人水平死亡率差异。经年龄调整后的死亡率和比率用于分析按住房变量划分的地区级死亡率差异:美国房主的出生时预期寿命平均比租房者长 3.5 岁(74.22 岁对 70.76 岁),男性与房主相关的长寿优势大于女性;美国印第安人/阿拉斯加原住民、非西班牙裔白人和非西班牙裔黑人的长寿优势大于亚裔/太平洋岛民和西班牙裔;美国出生者的长寿优势大于移民。与租房者相比,房主的全因死亡风险降低了 22%,儿童死亡率降低了 15%,青少年死亡率降低了 17%,心血管疾病、所有癌症、胃癌、肝癌、食道癌和宫颈癌、糖尿病、流感和肺炎、慢性阻塞性肺病、肝硬化、肾病、艾滋病、传染病、意外伤害、自杀和他杀的死亡率显著降低:在美国,住房的几个方面与预期寿命、儿童和青少年死亡率以及全因和特定原因死亡率密切相关。旨在为发达国家和发展中国家的居民提供精心设计、方便使用且价格合理的住房的政策,是解决弱势个人和社区健康的最基本决定因素之一以及减少全球健康不平等的重要政策选择。
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引用次数: 0
Factors Affecting Paramedic Personnel in the Assessment and Management of Emergency Pediatric Patients within the Prehospital Settings in the United Kingdom. 影响护理人员在英国院前急救儿科患者评估和管理的因素。
Pub Date : 2023-01-01 DOI: 10.21106/ijma.600
Carl Dowling

A paramedic's role in the United Kingdom is to primarily respond and provide emergency medical care to patients in the community. Pediatric patients form a small percentage of ambulance call-outs per year, which impacts a paramedic's confidence and competence when implementing effective healthcare protocols due to few attempts and existing opportunities to address pediatric patients' needs. There are also pre-existing gaps and barriers in pediatric emergency paramedic education and the lack of exposure to that specific patient group for emergency medical service healthcare providers in the prehospital settings when responding to pediatric medical emergencies. Further guidance and support in paramedic practice and education could be advantageous in providing effective tools and knowledge to improve pediatric emergency care in prehospital settings.

在联合王国,护理人员的作用主要是对社区病人作出反应并提供紧急医疗护理。儿科患者每年在救护车呼叫中所占的比例很小,这影响了护理人员在实施有效医疗保健协议时的信心和能力,因为很少有尝试和现有的机会来解决儿科患者的需求。在儿科急救护理人员教育方面也存在着预先存在的差距和障碍,院前急救医疗服务保健提供者在应对儿科医疗紧急情况时缺乏对特定患者群体的接触。在护理实践和教育方面的进一步指导和支持可能有利于提供有效的工具和知识,以改善院前儿科急诊护理。
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引用次数: 0
Digital Well-being Through the Use of Technology-A Perspective. 通过使用技术实现数字幸福——一个视角。
Pub Date : 2023-01-01 DOI: 10.21106/ijma.588
Sudip Bhattacharya, Sandip Bhattacharya, Vidisha Vallabh, Roy Rillera Marzo, Ruchi Juyal, Ozden Gokdemir

"No man is an island unto himself" - John Donne According to the World Health Organization, health is "a state of complete physical, mental and social well-being and not merely the absence of disease and infirmity." Our healthcare industry, public behaviors, and environment have grown exponentially with digital technologies in the era of the 4th industrial revolution. Due to rapid digitalization and easy availability of the internet, we are now online round the clock on our digital devices, leaving behind digital traces/information. These digital footprints serve as an increasingly fruitful data source for social scientists, including those interested in demographic research. The collection and use of digital data (quantitative and qualitative) also present numerous statistical and computational opportunities, further motivating the development of new research approaches to address health issues. In this paper, we have described the concept of digital well-being and proposed how we can use digital information for good health.

“没有人是孤立的孤岛”——约翰·多恩根据世界卫生组织的定义,健康是“一种身体、精神和社会完全健康的状态,而不仅仅是没有疾病和虚弱。”在第四次工业革命时代,随着数字技术的发展,我们的医疗保健行业、公众行为、环境都呈指数级增长。由于数字化的快速发展和互联网的便捷使用,我们现在在我们的数字设备上全天候在线,留下了数字痕迹/信息。这些数字足迹为社会科学家提供了越来越丰富的数据来源,包括那些对人口研究感兴趣的人。数字数据(定量和定性)的收集和使用也提供了许多统计和计算机会,进一步推动开发新的研究方法来解决卫生问题。在本文中,我们描述了数字健康的概念,并提出了我们如何利用数字信息促进健康。
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引用次数: 0
Interbirth Intervals of Immigrant and Refugee Women in the United States: A Cross-Sectional Study. 美国移民妇女与难民妇女生育间隔:一项横断面研究。
Pub Date : 2023-01-01 DOI: 10.21106/ijma.621
Comfort Z Olorunsaiye, Larissa R Brunner Huber, Samira P Ouedraogo

Background and objective: Despite guidelines recommending an interval of at least 18-24 months between a live birth and the conception of the next pregnancy, nearly one-third of pregnancies in the United States are conceived within 18 months of a previous live birth. The purpose of this study was to examine the associations between multiple immigration-related variables and interbirth intervals among reproductive-aged immigrant and refugee women living in the United States.

Methods: This was a cross-sectional, quantitative study on the sexual and reproductive health (SRH) of reproductive-aged immigrant and refugee women in the United States. The data were collected via an online survey administered by Lucid LLC. We included data on women who had complete information on nativity and birth history in the descriptive analysis (n = 653). The exposure variables were immigration pathway, length of time since immigration, and country/region of birth. The outcome variable was interbirth interval (≤18, 19-35, or ≥36 months). We used multivariable ordinal logistic regression, adjusted for confounders, to determine the factors associated with having a longer interbirth interval among women with second- or higher-order births (n = 245).

Results: Approximately 37.4% of study participants had a short interbirth interval. Women who immigrated to the United States for educational (aOR = 4.57; 95% CI, 1.57-9.58) or employment opportunities (aOR = 2.27; 95% CI, 1.07-5.31) had higher odds of reporting a longer interbirth interval (19-35 or ≥36 months) than women born in the United States. Women born in an African country had 0.79 times the odds (aOR = 0.79; 95% CI, 0.02-0.98) of being in a higher category of interbirth interval.

Conclusion and global health implications: Although all birthing women should be counseled on optimal birth spacing through the use of postpartum contraception, immigrant and refugee women would benefit from further research and policy and program interventions to help them in achieving optimal birth spacing. SRH research in African immigrant and refugee communities is especially important for identifying ameliorable factors for improving birth spacing.

背景和目的:尽管指南建议活产和下一次怀孕之间至少间隔18-24个月,但在美国,近三分之一的怀孕是在上一次活产后的18个月内怀孕的。本研究的目的是检验生活在美国的育龄移民和难民妇女中多个移民相关变量与生育间隔之间的关系。方法:对美国育龄移民和难民妇女的性健康和生殖健康(SRH)进行横断面定量研究。数据通过Lucid LLC管理的在线调查收集。我们在描述性分析中纳入了具有完整出生和出生史信息的妇女的数据(n = 653)。暴露变量为移民途径、移民时间长短和出生国家/地区。结局变量为生育间隔期(≤18、19-35或≥36个月)。我们使用多变量有序逻辑回归,调整混杂因素,以确定与二胎或高胎妇女生育间隔较长相关的因素(n = 245)。结果:大约37.4%的研究参与者的生育间隔较短。因教育原因移民美国的女性(aOR = 4.57;95% CI, 1.57-9.58)或就业机会(aOR = 2.27;95% CI, 1.07-5.31)报告生育间隔较长(19-35个月或≥36个月)的几率高于在美国出生的妇女。出生在非洲国家的女性有0.79倍的几率(aOR = 0.79;95% CI, 0.02-0.98)表明出生间隔较高。结论及其对全球健康的影响:虽然应通过使用产后避孕措施向所有生育妇女提供关于最佳生育间隔的咨询,但移民和难民妇女将受益于进一步的研究以及帮助她们实现最佳生育间隔的政策和方案干预措施。非洲移民和难民社区的性健康和生殖健康研究对于确定改善生育间隔的可改善因素尤其重要。
{"title":"Interbirth Intervals of Immigrant and Refugee Women in the United States: A Cross-Sectional Study.","authors":"Comfort Z Olorunsaiye,&nbsp;Larissa R Brunner Huber,&nbsp;Samira P Ouedraogo","doi":"10.21106/ijma.621","DOIUrl":"https://doi.org/10.21106/ijma.621","url":null,"abstract":"<p><strong>Background and objective: </strong>Despite guidelines recommending an interval of at least 18-24 months between a live birth and the conception of the next pregnancy, nearly one-third of pregnancies in the United States are conceived within 18 months of a previous live birth. The purpose of this study was to examine the associations between multiple immigration-related variables and interbirth intervals among reproductive-aged immigrant and refugee women living in the United States.</p><p><strong>Methods: </strong>This was a cross-sectional, quantitative study on the sexual and reproductive health (SRH) of reproductive-aged immigrant and refugee women in the United States. The data were collected via an online survey administered by Lucid LLC. We included data on women who had complete information on nativity and birth history in the descriptive analysis (n = 653). The exposure variables were immigration pathway, length of time since immigration, and country/region of birth. The outcome variable was interbirth interval (≤18, 19-35, or ≥36 months). We used multivariable ordinal logistic regression, adjusted for confounders, to determine the factors associated with having a longer interbirth interval among women with second- or higher-order births (n = 245).</p><p><strong>Results: </strong>Approximately 37.4% of study participants had a short interbirth interval. Women who immigrated to the United States for educational (aOR = 4.57; 95% CI, 1.57-9.58) or employment opportunities (aOR = 2.27; 95% CI, 1.07-5.31) had higher odds of reporting a longer interbirth interval (19-35 or ≥36 months) than women born in the United States. Women born in an African country had 0.79 times the odds (aOR = 0.79; 95% CI, 0.02-0.98) of being in a higher category of interbirth interval.</p><p><strong>Conclusion and global health implications: </strong>Although all birthing women should be counseled on optimal birth spacing through the use of postpartum contraception, immigrant and refugee women would benefit from further research and policy and program interventions to help them in achieving optimal birth spacing. SRH research in African immigrant and refugee communities is especially important for identifying ameliorable factors for improving birth spacing.</p>","PeriodicalId":30480,"journal":{"name":"International Journal of MCH and AIDS","volume":"12 1","pages":"e621"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/77/IJMA-12-e621.PMC10141878.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9803246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Morbidity and Mortality of HIV-Exposed Uninfected Infants in a Tertiary Referral Facility in Yaoundé, Cameroon. 喀麦隆雅温得一家三级转诊机构中暴露于艾滋病毒的未感染婴儿的发病率和死亡率。
Pub Date : 2023-01-01 Epub Date: 2023-12-23 DOI: 10.21106/ijma.663
Anne E Njom Nlend, Pascal Avenec, Jeannette Epée Ngoué, Arsène B Sandie

Background and objective: Following the recorded progress in the prevention of mother-to-child transmission of HIV in Yaoundé, Cameroon, the proportion of HIV-exposed infants who are uninfected (UIH) is increasing. These children are subject to infectious and non-infectious fragility. The purpose of this study was to assess infectious morbidity and mortality rates among UIH in Yaoundé, Cameroon.

Methods: We conducted a retrospective cohort study. Infants were included in the study and defined as the study subjects if they were between the ages of 24 months or younger, if they were born to HIV-positive mothers, and if they were confirmed to be HIV-negative. The main study outcomes were morbidity rate (defined as infectious, clinical events that required consultation or hospitalization) and death. Data were entered and saved in the Census and Survey Processing System (Cspro) 7.3. Statistical analyses were performed in R Software 3.6.2. The significance level was set at 0.05.

Results: In total, 240 subjects were recruited of whom 53.3% were males. Most of the HIV-positive mothers (95.7%) had used combination antiretroviral (ARV) therapy for at least four weeks during pregnancy. Among the subjects, 93.2% received ARV prophylaxis, 68.7% were exclusively breastfed for six months, 94.7% were fully vaccinated, and 60.6% had received cotrimoxazole up to the detection of the non-infection. Overall, the morbidity rate stood at 34.2%. The incidence of morbidity was 3 per 1,000 child months of the follow-up. The main pathologies were acute respiratory infections (60.79%) and malaria (17.65%). Three deaths were recorded, representing an overall mortality rate of 1.25% for an incidence of 1.1 per 1,000 child months of the follow-up (FU). Clinical events were more frequent in mothers diagnosed with HIV during pregnancy under the azidothymidine (AZT) + lamivudine (3TC) + névirapine (NVP) -based protocol (odds ratio of 3.83 [1.09-14.45; p = 0.039]). Morbidity was also higher for the follow-up periods of less than six months.

Conclusion and global health implications: The overall mortality rate among UIH was low. However, the morbidity rate was considerably higher. Emphasis should be focused on in-care retention for up to 24 months for all UIH, which should include monitoring of HIV-infected mothers prior to pregnancy.

背景和目的:喀麦隆雅温得市在预防母婴传播艾滋病方面取得了显著进展,但受艾滋病病毒感染的未感染婴儿(UIH)比例却在增加。这些儿童会出现感染性和非感染性脆弱性。本研究旨在评估喀麦隆雅温得未感染艾滋病毒婴儿的感染性发病率和死亡率:我们进行了一项回顾性队列研究。婴儿年龄在 24 个月或 24 个月以下、由 HIV 阳性母亲所生、HIV 阴性的婴儿均被纳入研究范围。研究的主要结果是发病率(定义为需要就诊或住院的感染性临床事件)和死亡率。数据在人口普查和调查处理系统(Cspro)7.3 中输入和保存。统计分析在 R 软件 3.6.2 中进行。显著性水平设定为 0.05:共招募了 240 名受试者,其中 53.3% 为男性。大多数艾滋病毒呈阳性的母亲(95.7%)在怀孕期间使用过至少四周的抗逆转录病毒(ARV)联合疗法。其中,93.2%的受试者接受了抗逆转录病毒预防治疗,68.7%的受试者进行了为期六个月的纯母乳喂养,94.7%的受试者接受了全面的疫苗接种,60.6%的受试者在发现未感染前接受了复方新诺明治疗。总的来说,发病率为 34.2%。在随访期间,每 1 000 个儿童月的发病率为 3 例。主要病症是急性呼吸道感染(60.79%)和疟疾(17.65%)。有 3 例死亡记录,总死亡率为 1.25%,发病率为每千个随访月 1.1 例(FU)。在基于阿齐多胸苷(AZT)+拉米夫定(3TC)+奈韦拉平(NVP)的方案下,在怀孕期间被诊断出感染艾滋病毒的母亲发生临床事件的频率更高(几率比为 3.83 [1.09-14.45; p = 0.039])。随访时间少于 6 个月的患者发病率也较高:UIH 的总死亡率较低。结论和对全球健康的影响:UIH 的总死亡率较低,但发病率却相当高。重点应放在对所有 UIH 进行长达 24 个月的随访上,其中应包括在怀孕前对感染 HIV 的母亲进行监测。
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引用次数: 0
Correlation Between Plasma Vitamin C Concentration and COVID-19 Outcomes among Patients Seen at a Major Hospital in the United Arab Emirates. 在阿拉伯联合酋长国一家大医院就诊的患者血浆维生素C浓度与COVID-19结局的相关性
Pub Date : 2022-01-01 DOI: 10.21106/ijma.608
Wael Hafez, Sana Osman, Muneir Gador, Dina Khair, Muhammad Aslam

Background and objective: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a newly emerged coronavirus that causes coronavirus disease-2019 (COVID-19) with varying degrees of disease manifestations. Vitamin C is an essential water-soluble vitamin with anti-inflammatory, antioxidant, antiviral, and immunomodulatory functions. The study aimed to investigate the association between serum vitamin C concentration and outcomes of COVID-19 among adults in the United Arab Emirates (UAE).

Methods: This retrospective observational study included 67 COVID-19 patients aged 30-59 years old. Measurement of vitamin C levels was performed at the National Reference Laboratory, UAE using liquid chromatography-tandem mass spectrometry (LC/MS-MS). The cut-off value was 0.4 mg/dl; plasma levels that ranged from 0.4 to 2 mg/dl were defined as sufficient. Values above 2 mg/dl were recognized as high and values less than 0.4 mg/dl are considered low or deficient.

Results: Among the included patients, 58.2% suffered from vitamin C deficiency. We found a statistically significant correlation between the concentration of serum vitamin C and age (p=0.03), the presence of hypertension (p=0.013), diabetes (p=0.01), and the development of pneumonia (p=0.012). There was no significant correlation between the concentration of serum vitamin C and the need for mechanical ventilation, Intensive Care Unit (ICU) admission, COVID-19 severity, or mortality. The risk of COVID-19 severity decreased in patients with sufficient vitamin C levels by 52% compared to patients with vitamin C deficiency (p=0.177). There was a statistically significant correlation between vitamin C sufficiency and low lactate dehydrogenase, C-reactive protein (CRP), and fibrinogen. However, the odds of vitamin C sufficiency in COVID-19 patients were significantly associated with lowering CRP levels (OR=0.99, 95% CI (0.98-1.00), p=0.024).

Conclusion and global health implications: Low serum vitamin C concentrations were associated with several demographic characteristics of patients, the presence of pneumonia, and inflammation. Furthermore, improving our social determinants, such as how we live, eat, drink, and vitamin C supplementation could positively impact the future health of the individual, community, and population.

背景与目的:严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)是一种新型冠状病毒,可引起冠状病毒病-2019 (COVID-19),具有不同程度的疾病表现。维生素C是一种必需的水溶性维生素,具有抗炎、抗氧化、抗病毒和免疫调节功能。该研究旨在调查阿拉伯联合酋长国成年人血清维生素C浓度与COVID-19结局之间的关系。方法:回顾性观察研究纳入67例年龄30 ~ 59岁的COVID-19患者。在阿联酋国家参考实验室使用液相色谱-串联质谱法(LC/MS-MS)测量维生素C水平。临界值为0.4 mg/dl;血浆水平在0.4到2毫克/分升之间被定义为足够。高于2毫克/分升被认为是高,低于0.4毫克/分升被认为是低或不足。结果:58.2%的患者存在维生素C缺乏症。我们发现血清维生素C浓度与年龄(p=0.03)、高血压(p=0.013)、糖尿病(p=0.01)和肺炎(p=0.012)之间存在统计学意义上的显著相关性。血清维生素C浓度与机械通气需求、重症监护病房(ICU)入院、COVID-19严重程度或死亡率之间无显著相关性。与缺乏维生素C的患者相比,维生素C水平充足的患者发生COVID-19严重程度的风险降低了52% (p=0.177)。维生素C充足性与低乳酸脱氢酶、C反应蛋白(CRP)和纤维蛋白原之间有统计学意义的相关性。然而,COVID-19患者维生素C充足的几率与CRP水平降低显著相关(OR=0.99, 95% CI (0.98-1.00), p=0.024)。结论和全球健康影响:低血清维生素C浓度与患者的几个人口统计学特征、肺炎和炎症的存在有关。此外,改善我们的社会决定因素,如我们如何生活、饮食和补充维生素C,可能会对个人、社区和人口的未来健康产生积极影响。
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引用次数: 0
Considerations about Reducing False-Negative PCR Test for COVID-19. 关于减少COVID-19 PCR假阴性检测的思考
Pub Date : 2022-01-01 Epub Date: 2022-11-28 DOI: 10.21106/ijma.571
Alireza Ghannad Sabzevari, Mohsen Nikbakht

Polymerase chain reaction (PCR) for the detection of nucleic acids is the gold standard test for the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is the probability of false-negative results with this test, which poses a threat to public health. Here, we highlight some important factors that should be considered for reducing the false-negative results of the SARS-CoV-2 PCR test.

聚合酶链反应(PCR)检测核酸是诊断严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)的金标准检测。然而,这种检测有可能产生假阴性结果,对公众健康构成威胁。在此,我们强调了减少SARS-CoV-2 PCR检测假阴性结果应考虑的一些重要因素。
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引用次数: 0
Theory-Driven, Multi-Stage Process to Develop a Culturally-Informed Anti-Stigma Intervention for Pregnant Women Living with HIV in Botswana. 理论驱动,多阶段的过程,以发展文化知情的反污名干预怀孕妇女艾滋病毒感染者在博茨瓦纳。
Pub Date : 2022-01-01 DOI: 10.21106/ijma.569
Ohemaa B Poku, Timothy D Becker, Shathani Rampa, Supriya Misra, Ari R Ho-Foster, Patlo Entaile, Charisse Tay, Karen Choe, Tonya Arscott-Mills, Michael B Blank, Philip Renison Opondo, Lawrence H Yang

Background and objectives: Despite a well-established universal HIV diagnosis and treatment program, Botswana continues to face a high HIV prevalence, in large part due to persistent stigma, which particularly affects pregnant women and interferes with healthcare engagement. Tackling stigma as a fundamental cause of HIV disparities is an important but understudied aspect of current HIV interventions. Our multinational and multicultural team used a theory-driven, multi-stage iterative process to develop measures and interventions to first identify and then target the most culturally-salient aspects of stigma for mothers living with HIV in Botswana. This methodology report examines the stage-by-stage application of the "What Matters Most" (WMM) theory and lessons learned, sharing a replicable template for developing culturally-shaped anti-stigma interventions.

Methods: First, we conducted initial qualitative work based on the WMM theory to identify key structural and cultural factors shaping stigma for women living with HIV in Botswana. Second, we developed a psychometrically validated scale measuring how "what matters most" contributes to and protects against stigma for this population. Third, we designed an anti-stigma intervention, "Mothers Moving towards Empowerment" (MME), centered on the local values identified using WMM theory that underly empowerment and motherhood by adapting a cognitive behavioral therapy (CBT)-informed, group-based, and peer-co-led anti-stigma intervention specifically for pregnant women living with HIV. Fourth, we conducted a pilot study of MME in which participants were allocated to two trial arms: intervention or treatment-as-usual control.

Results: Our qualitative research identified that bearing and caring for children are capabilities essential to the concept of respected womanhood, which can be threatened by a real or perceived HIV diagnosis. These values informed the development and validation of a scale to measure these culturally-salient aspects of stigma for women living with HIV in Botswana. These findings further informed our intervention adaptation and pilot evaluation, in which the intervention group showed significant decreases in HIV stigma and depressive symptoms compared to the control group. Participants reported overcoming reluctance to disclose their HIV status to family, leading to improved social support.

Conclusion and global health implications: Previous studies have not utilized culturally-based approaches to assess, resist, and intervene with HIV-related stigma. By applying WMM in each stage, we identified cultural and gendered differences that enabled participants to resist HIV stigma. Focusing on these capabilities that enable full personhood, we developed an effective culturally-tailored anti-stigma intervention for pregnant women living with HIV in Botswana. This theory-driven, multi-stage approach can

背景和目标:尽管建立了一个完善的普遍艾滋病毒诊断和治疗方案,博茨瓦纳仍然面临着很高的艾滋病毒流行率,这在很大程度上是由于持续的耻辱,这尤其影响到孕妇,并干扰了医疗保健参与。将耻辱感作为艾滋病毒差异的根本原因,是当前艾滋病毒干预措施的一个重要但尚未得到充分研究的方面。我们的跨国和多元文化团队采用理论驱动的多阶段迭代过程来制定措施和干预措施,首先确定并针对博茨瓦纳感染艾滋病毒的母亲最突出的文化耻辱感方面。本方法论报告考察了“最重要的是什么”(WMM)理论和经验教训的逐步应用,为制定文化塑造的反污名干预措施分享了可复制的模板。方法:首先,我们基于WMM理论进行了初步定性工作,以确定博茨瓦纳女性艾滋病毒感染者污名化的关键结构和文化因素。其次,我们开发了一种心理测量学验证的量表,测量“最重要的”如何对这一人群产生影响并保护他们免受耻辱感。第三,我们设计了一种反污名化干预,“母亲走向赋权”(MME),以使用WMM理论确定的地方价值观为中心,通过采用认知行为疗法(CBT)为基础,以群体为基础,以同伴为主导,专门针对感染艾滋病毒的孕妇进行反污名化干预。第四,我们进行了一项MME的试点研究,其中参与者被分配到两个试验组:干预组或常规治疗组。结果:我们的定性研究发现,生育和照顾孩子是受尊重的女性概念的基本能力,这可能会受到真实或感知的艾滋病毒诊断的威胁。这些价值观为制定和验证一个量表提供了依据,以衡量博茨瓦纳感染艾滋病毒的妇女所面临的这些文化上突出的耻辱方面。这些发现进一步为我们的干预适应和试点评估提供了信息,在干预组中,与对照组相比,HIV耻辱感和抑郁症状显著减少。参与者报告说,他们克服了不愿向家人透露自己的艾滋病毒状况,从而改善了社会支持。结论和全球健康影响:以前的研究没有利用基于文化的方法来评估、抵制和干预与艾滋病毒相关的耻辱。通过在每个阶段应用WMM,我们确定了使参与者能够抵制艾滋病毒污名的文化和性别差异。专注于这些实现完整人格的能力,我们为博茨瓦纳感染艾滋病毒的孕妇开发了一种有效的文化定制反污名干预措施。这种理论驱动的多阶段方法可以复制,以在其他结果、人群和环境中实现减少耻辱感。
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引用次数: 0
Malaria Elimination: What Can Africa Learn from China? 消除疟疾:非洲可以向中国学习什么?
Pub Date : 2022-01-01 Epub Date: 2022-11-29 DOI: 10.21106/ijma.526
Claude Ngwayu Nkfusai, Olivia Ngou, Caroline Ekoko Subi, Sofia Mohlin, Fidele Bemadoum, Sylvanus Teboh, Frankline Sevidzem Wirsiy, Luchuo Engelbert Bain

For decades now, malaria has been an important public health concern in Africa, which bears the greatest burden for the disease, affecting children and adults alike. Although a few countries (Australia, Brunei, Singapore, and Algeria, among others) have previously eliminated malaria, the World Health Organization (WHO), on June 30, 2021, declared China malaria-free. This commentary seeks to explore what China did differently to eliminate malaria and what Africa can learn from China's experience. First, Africa can use innovative tools and strategies used by China to attain success. Second, Africa can create a multi-sector collaboration among Heads of States in high burden malaria-affected countries by involving all stakeholders such as ministries of health, finance, research, education, development, public security, the army, police, commerce, industry, and information technology, customs, media and tourism to jointly fight malaria in all African countries. Furthermore, African countries could adapt the genetics-based approaches used by China in the elimination of mosquito breeding grounds. Finally, Africa can also adapt a better surveillance system of reporting on malaria daily as China did in their experience.

几十年来,疟疾一直是非洲一个重要的公共卫生问题,非洲承受着最沉重的疾病负担,儿童和成人都受到影响。虽然一些国家(澳大利亚、文莱、新加坡和阿尔及利亚等)此前已经消灭了疟疾,但世界卫生组织(世卫组织)于2021年6月30日宣布中国为无疟疾国家。本文旨在探讨中国在消除疟疾方面的不同之处,以及非洲可以从中国的经验中学到什么。第一,非洲可以借鉴中国的创新工具和战略来取得成功。第二,非洲可以在疟疾高负担国家的国家元首之间建立多部门合作,让卫生、财政、研究、教育、发展、公安、军队、警察、商业、工业和信息技术、海关、媒体和旅游业等所有利益攸关方参与,共同在所有非洲国家防治疟疾。此外,非洲国家可以采用中国在消除蚊子滋生地中使用的基于遗传学的方法。最后,非洲还可以像中国的经验那样,采用更好的监测系统,每天报告疟疾情况。
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引用次数: 0
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International Journal of MCH and AIDS
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