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Prevalence and Predictors of Postpartum Depression: Northwest Ethiopia. 埃塞俄比亚西北部产后抑郁症的患病率和预测因素。
Pub Date : 2020-01-21 eCollection Date: 2020-01-01 DOI: 10.1155/2020/9565678
Mengstu Melkamu Asaye, Haymanot Alem Muche, Eyerusalem Desta Zelalem

Background: Postpartum depression is an umbrella, which encompasses several mood disorders that follow childbirth within 6 weeks. Screening for postpartum depression would improve the ability to recognize these disorders and enhance care that ensures improved clinical outcomes. Early identification of postpartum depression is important in order to plan for implementation strategies that allow for timely treatment and support of women with postpartum depression.

Objective: To determine the prevalence and associated factors of postpartum depression among women who gave birth in the last six weeks in Gondar town, Northwest Ethiopia, 2018.

Methods: A community based cross-sectional study was conducted among 526 women who gave birth in the last 6 weeks from July 1 to 30, 2018 in Gondar town. Cluster sampling technique was used. Data were collected by semi-structured and pretested questionnaire and entered into epi-Info version 7.0 and then analyzed by SPSS version 20.0. Both bivariate and multivariable logistic regression model were fitted. Adjusted odds ratio with 95% confidence interval has been computed and variables with p-value <0.05 were considered statistically significant.

Results: The prevalence of postpartum depression among 526 postnatal women was 25% (95% CI: 21, 28). Abortion history (AOR = 1.79, 95% CI: 1.07, 2.97), birth weight <2.5 kg (AOR = 3.12, 95% CI: 1.78, 5.48), gestational age below 36 weeks (AOR = 2.18, 95% CI: 1.22, 3.88) unplanned pregnancy (AOR = 2.02, 95% CI: 1.24, 3.31), relatives' mental illness (AOR = 1.20: 1.09-3.05), had no antenatal visit (AOR = 4.05, 95% CI: 1.81, 9.05), had no postnatal visit (AOR = 1.82, 95% CI: 1.11, 3.00) were factors significantly associated with postpartum depression. Conclusion and Recommendations. The prevalence of PPD was found to be higher. Variables like abortion history, low birth weight, gestational age below 36 weeks, unplanned pregnancy, relatives' mental illness, had no antenatal visit, and had no postnatal visit were predisposing factors to postpartum depression. Preventive measures to avoid low birth weight and pregnancy complications are also identified as proactive ways to reduce postpartum depression. Early identification and treatment of depression during ANC and postpartum care can mitigate the impact of PPD on the mother-baby dyad. Emphasis must be given women to have ANC and PNC follow up.

背景:产后抑郁症是一把保护伞,包括分娩后6周内出现的几种情绪障碍。产后抑郁症的筛查将提高识别这些疾病的能力,并加强护理,确保改善临床结果。产后抑郁症的早期识别非常重要,以便制定实施战略,以便及时治疗和支持患有产后抑郁症的妇女。目的:了解2018年埃塞俄比亚西北部贡达尔镇近6周分娩妇女产后抑郁症的患病率及相关因素。方法:对贡达尔镇2018年7月1日至30日6周内分娩的526名妇女进行了基于社区的横断面研究。采用整群抽样技术。采用半结构化预测问卷收集数据,录入epi-Info 7.0版本,采用SPSS 20.0版本进行统计分析。拟合了双变量和多变量logistic回归模型。经校正的优势比(95%置信区间)和变量p值计算结果:526名产后妇女产后抑郁症患病率为25% (95% CI: 21,28)。流产史(AOR = 1.79, 95% CI: 1.07, 2.97)、出生体重。发现PPD的患病率较高。流产史、低出生体重、胎龄低于36周、意外怀孕、亲属精神疾病、产前未访视、产后未访视是产后抑郁的易感因素。避免低出生体重和妊娠并发症的预防措施也被确定为减少产后抑郁症的积极方法。产前和产后护理早期识别和治疗抑郁症可以减轻产后抑郁症对母婴的影响。强调必须有女性国民大会和PNC跟进。
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引用次数: 24
Prevalence of Common Mental Disorder and Its Association with Khat Chewing among Ethiopian College Students: A Systematic Review and Meta-Analysis. 埃塞俄比亚大学生中常见精神障碍的患病率及其与咀嚼阿拉伯茶的关系:一项系统综述和荟萃分析。
Pub Date : 2020-01-06 eCollection Date: 2020-01-01 DOI: 10.1155/2020/1462141
Birhanie Mekuriaw, Abriham Zegeye, Alemayehu Molla, Robel Hussen, Solomon Yimer, Zelalem Belayneh

Background: Mental disorder is a global burden that affects all groups of people. Young people, particularly college/university students, are more vulnerable to common mental disorders than the general population. Thus, students may use khat to gain immediate relief from their psychological distress which may worsen again after longer time of chewing. In Ethiopia, there are studies showing discrepant and inconsistent results of common mental disorder among college/university students. Therefore, this review sought to determine the prevalence of common mental disorder and its association with khat chewing among Ethiopian college/university students.

Methods: Different kinds of literature were searched from the databases of Google Scholar, PubMed/Medline, ScienceDirect, and PsycINFO. A total of 10 primary studies which report the prevalence of common mental disorder among Ethiopian college/university students were included in the review. The data were extracted using a standardized data extraction format prepared in Microsoft Excel. STATA version 14 statistical software was used for analysis. Cochran's Q test statistics and I 2 test were used to assess heterogeneity. A random effects meta-analysis model was used to estimate the pooled prevalence of common mental disorder due to the variability of the studies. Lastly, the association between common mental disorder and khat chewing was conducted.

Results: The pooled prevalence of common mental disorder among Ethiopian college/university students was 37.73% (95% CI: 30.43, 45.03). The subgroup analysis showed the highest [51.9% (95% CI: 30.19, 73.70)] and lowest [33.28% (95% CI: 19.95, 46.60)] prevalences of common mental disorder among Ethiopian college/university students found in Amhara and South Nation Nationality and People regions, respectively. The pooled effect (odds ratio) of khat chewing on common mental disorder was 2.01 (95% CI: 1.38, 2.95).

Conclusions: In our review, it is found that more than one-third of college/university students suffered from common mental disorder. Khat chewers were found to be twofolds more vulnerable to develop common mental disorder than nonchewers.

背景:精神障碍是影响所有人群的全球性负担。年轻人,特别是大学生,比一般人更容易患常见的精神障碍。因此,学生可以使用阿拉伯茶来立即缓解他们的心理困扰,这种困扰可能会在咀嚼更长的时间后再次恶化。在埃塞俄比亚,有研究表明,大学生中常见精神障碍的结果存在差异和不一致。因此,本综述试图确定埃塞俄比亚大学生中常见精神障碍的患病率及其与咀嚼阿拉伯茶的关系。方法:从Google Scholar、PubMed/Medline、ScienceDirect和PsycINFO数据库中检索不同类型的文献。共有10项报告埃塞俄比亚学院/大学生中常见精神障碍流行情况的初步研究被纳入审查。采用Microsoft Excel编制的标准化数据提取格式提取数据。采用STATA version 14统计软件进行分析。采用Cochran’s Q检验统计量和i2检验评估异质性。由于研究的可变性,随机效应荟萃分析模型被用于估计常见精神障碍的总患病率。最后,研究了常见精神障碍与咀嚼阿拉伯茶之间的关系。结果:埃塞俄比亚大学生中常见精神障碍的总患病率为37.73% (95% CI: 30.43, 45.03)。亚组分析显示,埃塞俄比亚大学生的常见精神障碍患病率最高[51.9% (95% CI: 30.19, 73.70)],最低[33.28% (95% CI: 19.95, 46.60)]分别出现在阿姆哈拉和南方民族地区。咀嚼阿拉伯茶对常见精神障碍的综合效应(优势比)为2.01 (95% CI: 1.38, 2.95)。结论:在我们的综述中发现,超过三分之一的大学生患有常见的精神障碍。研究发现,咀嚼阿拉伯茶的人患普通精神疾病的几率是不咀嚼阿拉伯茶的人的两倍。
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引用次数: 13
Affective and Psychotic Disorders in War-Torn Eastern Part of the Democratic Republic of the Congo: A Cross-Sectional Study. 饱受战争蹂躏的刚果民主共和国东部地区的情感和精神障碍:一项横断面研究。
Pub Date : 2020-01-01 DOI: 10.1155/2020/9190214
Bives Mutume Vivalya, Germain Manzekele Bin Kitoko, Adelard Kalima Nzanzu, Martial Mumbere Vagheni, Rock Kasereka Masuka, Wilson Mugizi, Scholastic Ashaba

Background: There is lack of information about prevalence of affective and psychotic disorders triggered by traumatic events among people living in war-affected regions. This study is aimed at determining the prevalence rate of affective and psychotic disorders and the associated factors in a war-torn eastern part of Democratic Republic of the Congo.

Methods: This epidemiological cross-sectional descriptive study was carried out from 1st January 2019 to 31st December 2019 at Cepima and Muyisa health centers. This study enrolled 344 patients that had experienced traumatic events in Eastern Democratic Republic of the Congo from the 1119 participants, of whom 229 had positive bipolar affective disorder and 115 patients had psychotic disorders.

Results: The results revealed that bipolar affective disorders were two times more than psychotic disorders. Sexual abuse, sudden death of a relative, kidnapping, the physical torture, and childhood trauma were the psychological factors correlated to the occurrence of bipolar affective and psychotic disorders.

Conclusions: It was concluded that the traumatic experiences were precursors for the occurrence of bipolar affective and psychotic spectrum disorders.

背景:生活在受战争影响地区的人们缺乏关于创伤事件引发的情感和精神障碍患病率的信息。本研究旨在确定在刚果民主共和国饱受战争蹂躏的东部地区情感和精神障碍的患病率及其相关因素。方法:本流行病学横断面描述性研究于2019年1月1日至2019年12月31日在Cepima和Muyisa卫生中心进行。这项研究从1119名参与者中招募了344名在刚果民主共和国东部经历过创伤性事件的患者,其中229名患有阳性双相情感障碍,115名患有精神障碍。结果:双相情感障碍的发生率是精神障碍的2倍。性虐待、亲属猝死、绑架、体罚和童年创伤是双相情感和精神障碍发生的相关心理因素。结论:创伤经历是双相情感和精神谱系障碍发生的先兆。
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引用次数: 6
Insight and Associated Factors among Patients with Schizophrenia in Mental Specialized Hospital, Ethiopia, 2018. 埃塞俄比亚精神专科医院精神分裂症患者的洞察力及相关因素,2018。
Pub Date : 2019-11-17 eCollection Date: 2019-01-01 DOI: 10.1155/2019/2453862
Mandaras Tariku, Demeke Demilew, Tolesa Fanta, Meskerem Mekonnen, Dessie Abebaw Angaw

Background: Insight is the degree of the patient's awareness and understanding of their attributions, feelings, behavior and disturbing symptoms. Majority of the patients with schizophrenia have poor insight and insight is an important prognostic indicator in schizophrenia to enhance treatment compliances and reducing the risks of clinical deterioration. The main objective of this study was to assess insight and its associated factors among patients with schizophrenia at mental specialized hospital in Ethiopia.

Methods: Institutional based cross-sectional study was conducted from May to June 2018 Mental Specialized Hospital among 455 patients with schizophrenia. Insight was measured by an abridged version of Scale to assess unawareness of mental disorder. Positive and Negative Syndrome Scale, Calgary depressive scale, Oslo social support scale was used to identify factors associated with insight. Simple and multiple linear regression analysis were used to assess associated factors of insight in the participants.

Results: The mean score of insight was 13.66 (95% CI 13.27, 14.04). Age at first onset of illness, duration of treatments, depressive symptoms were inversely associated with mean insight score; whereas unemployed, positive and negative syndrome, previous hospitalization, >=2 episodes were positively associated with mean insight score.

Conclusion: Nearly half of the study participants were scored above the mean insight score so, the clinicians and psychotherapists should have to work together to improve insight among patients with schizophrenia.

背景:洞察力是指患者对自己的归因、感受、行为和困扰症状的认识和理解程度。大多数精神分裂症患者的洞察力较差,而洞察力是提高精神分裂症治疗依从性、降低临床恶化风险的重要预后指标。本研究的主要目的是评估埃塞俄比亚精神专科医院精神分裂症患者的洞察力及其相关因素。方法:对2018年5 - 6月精神专科医院455例精神分裂症患者进行机构横断面研究。洞察力是通过一个精简版的量表来评估精神障碍的无意识。采用正、负症候群量表、卡尔加里抑郁量表、奥斯陆社会支持量表来确定与洞察力相关的因素。使用简单和多元线性回归分析来评估参与者洞察力的相关因素。结果:洞察力平均得分为13.66分(95% CI 13.27, 14.04)。发病年龄、治疗持续时间、抑郁症状与平均洞察力得分呈负相关;而失业、阳性和阴性综合征、既往住院、>=2次发作与平均洞察力得分呈正相关。结论:近一半的研究参与者得分高于平均洞察力得分,因此,临床医生和心理治疗师应该共同努力提高精神分裂症患者的洞察力。
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引用次数: 7
Prevalence and Associated Factors of Violence against Hospital Staff at Amanuel Mental Specialized Hospital in Addis Ababa, Ethiopia 埃塞俄比亚亚的斯亚贝巴Amanuel精神专科医院对医院工作人员的暴力发生率及相关因素
Pub Date : 2019-11-05 DOI: 10.1155/2019/3642408
A. Abate, D. Abebaw, A. Birhanu, A. Zerihun, D. Assefa
Background. Violence at the workplace has become an alarming phenomenon worldwide. The real size of the problem is largely unknown and recent information shows that the current knowledge is only the tip of the iceberg. The enormous cost of violence at the workplace for person and community at large is becoming more apparent. It could be physical, sexual, and verbal in nature and could be actual or threatened. Objectives. To access prevalence and associated factors of violence against hospital staff at Amanuel Mental Specialized Hospital Addis Ababa, Ethiopia. Methods. An institution based cross-sectional study was employed in 2017. The data were collected using Workplace Violence in the Health Sector Country Case Study Questionnaire from 496 participants. Participants had been selected using simple random sampling technique and data were collected using a self-administered structured questionnaire. The collected data were entered into Epi-data version 3.1, and SPSS version 21 was used for Analysis. Binary logistic regression was fitted to identify factors associated with the outcome variable. Result. From 496 staff intended to have participated in this study, complete data were obtained from 435, making a response rate of 87.7%. This research showed high prevalence of violence and we have got that staff had been exposed to physical violence 36.8%, verbal violence 62.1%, and sexual violence 21.8 % over the past year, respectively. Age, sex, and contact with the patient were statistically significant variables (p < 0.05). Conclusion and Recommendation. According to this study, majority of AMSH staff were violated by the patient they care.
背景工作场所的暴力行为已成为全世界令人担忧的现象。这个问题的真实规模在很大程度上是未知的,最近的信息表明,目前的知识只是冰山一角。工作场所暴力行为给个人和整个社区带来的巨大代价越来越明显。它可能是身体上的、性的和言语上的,也可能是实际的或威胁的。目标。了解埃塞俄比亚亚的斯亚贝巴Amanuel精神专科医院暴力侵害医院工作人员的流行率和相关因素。方法。2017年采用了一项基于机构的横断面研究。数据是使用卫生部门国家案例研究问卷中的工作场所暴力从496名参与者中收集的。参与者是使用简单的随机抽样技术选择的,数据是使用自行管理的结构化问卷收集的。将收集的数据输入Epi数据3.1版,并使用SPSS 21版进行分析。二元逻辑回归用于确定与结果变量相关的因素。后果从496名有意参与这项研究的员工中,从435名员工中获得了完整的数据,回复率为87.7%。这项研究表明,暴力的发生率很高,我们发现员工在过去一年中分别遭受了36.8%的身体暴力、62.1%的言语暴力和21.8%的性暴力。年龄、性别和与患者的接触是具有统计学意义的变量(p<0.05)。结论和建议。根据这项研究,AMSH的大多数工作人员都受到了他们护理的患者的侵犯。
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引用次数: 8
Factors Associated with Depression among Heart Failure Patients at Cardiac Follow-Up Clinics in Northwest Ethiopia, 2017: A Cross-Sectional Study 2017年埃塞俄比亚西北部心脏随访诊所心力衰竭患者抑郁的相关因素:一项横断面研究
Pub Date : 2019-07-21 DOI: 10.1155/2019/6892623
Kassahun Gebeyehu Yazew, Debrework Tesgera Beshah, M. H. Salih, Tadele Amare Zeleke
Background Depression is a comorbid disorder in patients with heart failure and it is a major public health problem worldwide. Little is known about the depression among heart failure patients in low-income countries, while, in Ethiopia, none was studied. Objective This study is to assess the prevalence of depression and associated factors among heart failure patients at cardiac follow-up clinics at Amhara Region Referral Hospitals, Northwest Ethiopia, 2017. Methods A hospital based cross-sectional study was conducted between March 30, 2017, and May 15, 2017, G.C., by using a systematic random sampling technique to select 422 of 1395 HF patients. Structured interviewer-administered questionnaires and patient card review with a checklist that incorporates the PHQ-9 tool for depression measurement were used. The collected data were checked, coded, and entered into Epi-info version 7 and exported to SPSS version 20. Bivariate logistic regression at p-value <0.2 was exported to multivariate logistic regressions and p-value <0.05 was considered statistically significant. Results A total of 403 were included with a response rate of 95.5%. Among the participants, 51.1% had depressive symptoms. Factors associated with depressive symptoms were poor self-care behavior 1.60 [AOR (95% CI=1.01, 2.55)], poor social support 1.90 [AOR (95% CI=1.16, 3.12)], being female 2.70 [AOR (95% CI=1.44, 5.07)], current smoking history 4.96 [AOR (95% CI=1.54, 15.98)], and duration of heart failure (>1 year) 1.64 [AOR (95% CI=1.04, 2.59)]. Conclusions Around half of the patients were depressive. The patients who had poor self-care behavior, were females, had poor social support, had a current history of smoking, and had duration of chronic heart failure >1 year need special attention. Therefore, all referral hospitals need efforts to focus on those problems and target improvements of depressive symptoms.
背景抑郁症是心力衰竭患者的一种合并症,也是世界范围内的一个主要公共卫生问题。在低收入国家,人们对心力衰竭患者的抑郁症知之甚少,而在埃塞俄比亚,人们对此一无所知。目的本研究旨在评估2017年埃塞俄比亚西北部阿姆哈拉地区转诊医院心脏随访诊所心力衰竭患者的抑郁患病率及其相关因素。方法在2017年3月30日至2017年5月15日期间,采用系统随机抽样技术,对1395名HF患者中的422名进行了医院横断面研究。采用结构化访谈者管理的问卷调查和患者卡片审查,检查表中包含了PHQ-9抑郁测量工具。对收集的数据进行检查、编码,并将其输入Epi-info第7版,然后导出到SPSS第20版。p值为1年的双变量逻辑回归)1.64[AOR(95%CI=1.04,2.59)]。结论大约一半的患者患有抑郁症。自我保健行为不佳、女性、社会支持不佳、有吸烟史、慢性心力衰竭持续时间>1年的患者需要特别关注。因此,所有转诊医院都需要努力关注这些问题,并以改善抑郁症状为目标。
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引用次数: 20
Is There Association between Risky Sexual Behaviors and Depression Symptoms among Youth? A Case of Jimma University Students, Ethiopia. 青少年危险性行为与抑郁症状之间是否存在关联?埃塞俄比亚吉马大学学生一例
Pub Date : 2019-07-01 eCollection Date: 2019-01-01 DOI: 10.1155/2019/3757656
Yonas Tesfaye, Alemayehu Negash, Tsegaye Tewelde Gebrehiwot, Worknesh Tessema, Susan Anand, Gutema Ahmed, Daniel Alemu

Background: Risky Sexual Behaviors (RSB) and Depression symptoms expose young people to various reproductive health problems including sexually transmitted infections and HIV/AIDS. To date the link between these two major public health problems lacks empirical evidence in the context of higher education institutions in Ethiopia.

Objective: The aim of this study was to assess association between risky sexual behavior and depression symptoms among Jimma University main campus students, Jimma, Ethiopia, 2016.

Methods: An institution based quantitative cross sectional study was conducted. A pre-tested questionnaire and modified Beck Depression Inventory II were administered to 700 students, selected by multi-stage stratified sampling, from the main campus of Jimma University. Descriptive statistics, simple and multiple logistic regression models were used to analyze possible confounders. Presence of crude association between the dependent and independent variables was detected by bivariate logistic regression analysis. Variables with p value < 0.25 in bivariate analysis were analyzed by multivariable logistic regression to exclude the confounders. Adjusted odd ratios with 95%CI were computed to examine depression symptoms and other independent variables as predictors of RSB.

Results: RSB were reported by 30.2% students. Out of 222 (33.6%) students with depression symptoms 105 (47.3%) reported RSB. Students with moderate depression symptoms are nearly two times more likely to experience risky sexual behavior than students with no depression symptoms (AOR 1.9, 95% CI: 1-3.1). Students with severe depression symptoms are nearly two and half times more likely to experience RSB than students with no depression symptoms counterparts (AOR 2.6, 95%CI: 1.3- 5.1).

Conclusion: RSB were high among students with depression symptoms in the main campus of Jimma University. To help students overcome the challenges, recommendation was given for concerted action from the University, governmental and NGO, and the surrounding community to establish support services and various reproductive and mental health awareness programs within the campus.

背景危险性行为(RSB)和抑郁症状使年轻人面临各种生殖健康问题,包括性传播感染和艾滋病毒/艾滋病。迄今为止,这两个主要公共卫生问题之间的联系缺乏埃塞俄比亚高等教育机构的经验证据。目的本研究旨在评估2016年埃塞俄比亚吉马吉马大学主校区学生的危险性行为与抑郁症状之间的关系。方法采用基于机构的定量横断面研究。采用预测问卷和改良Beck抑郁量表II,对来自金马大学主校区的700名学生进行了多阶段分层抽样。使用描述性统计、简单和多元逻辑回归模型来分析可能的混杂因素。通过双变量逻辑回归分析检测因变量和自变量之间存在粗略关联。具有p值的变量 < 通过多变量逻辑回归分析双变量分析中的0.25,以排除混杂因素。计算95%置信区间的校正奇数比,以检查抑郁症状和其他独立变量作为RSB的预测因素。结果30.2%的学生报告RSB。在222名(33.6%)有抑郁症状的学生中,105名(47.3%)报告了RSB。有中度抑郁症状的学生发生危险性行为的可能性几乎是没有抑郁症状学生的两倍(AOR 1.9,95%CI:1-3.1)。有严重抑郁症状的同学发生RSB的可能性是没有抑郁症症状的同学的2.5倍(AOR2.6,95%CI+1.3-5.1)吉马大学主校区有抑郁症症状的学生。为了帮助学生克服挑战,建议大学、政府和非政府组织以及周边社区采取一致行动,在校园内建立支持服务和各种生殖和心理健康意识计划。
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引用次数: 0
Food Insecurity and Mental Distress among Mothers in Rural Tigray and SNNP Regions, Ethiopia 埃塞俄比亚农村提格雷和snp地区母亲的粮食不安全和精神困扰
Pub Date : 2019-06-19 DOI: 10.1155/2019/7458341
Tarik Taye Birhanu, A. Tadesse
Access to safe and adequate food is a basic human right under Article 25 of the Universal Declaration of Human Rights. Globally, more than 870 million people consume less calories than they require, which can lead to disabling physical and mental health outcomes. This study was designed to investigate the association between household food insecurity and mental distress among mothers in the Tigray and SNNP regions of Ethiopia. A community based cross-sectional survey was completed on a total of 2,992 households. A linear multiple regression model was used to study the association between food insecurity and mental distress. More than half of the study participants, 57.9%, were experiencing food insecurity. The prevalence of mental distress among the mothers was 39%. Food insecurity was significantly associated with mental distress after controlling for socioeconomic covariates. Integrating screening and management of mental distress would result in a better health status of the mothers and those under their care.
根据《世界人权宣言》第25条,获得安全和充足的食物是一项基本人权。在全球范围内,超过8.7亿人摄入的卡路里低于他们所需的卡路里,这可能导致身心健康状况不佳。本研究旨在调查埃塞俄比亚提格雷和SNNP地区母亲的家庭粮食不安全与精神困扰之间的关系。一项以社区为基础的横断面调查共对2,992个家庭进行了调查。采用线性多元回归模型研究粮食不安全与心理困扰之间的关系。超过一半的研究参与者(57.9%)正在经历粮食不安全。母亲中精神困扰的患病率为39%。在控制社会经济协变量后,食物不安全与精神痛苦显著相关。对精神痛苦进行综合筛查和管理将改善母亲及其照顾对象的健康状况。
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引用次数: 5
Use of Long-Acting Injectable Antipsychotic in an Inpatient Unit of a Community Teaching Hospital 长效注射抗精神病药物在某社区教学医院住院部的应用
Pub Date : 2019-06-13 DOI: 10.1155/2019/8629030
Olaniyi Olayinka, Ayotomide Oyelakin, Karthik Cherukupally, Inderpreet Virk, Chiedozie Ojimba, S. Khadka, A. Maksymenko, Patrice Fouron, Taher Khandaker, Tolu Olupona, Jason Hershberger
Background Individuals with Schizophrenia Spectrum Disorders (SSD) often experience significant impairment in educational, occupational, and psychosocial functioning. The clinical benefit of long-acting injectable antipsychotics (LAIs) in the management of patients with SSD is well established. SSD patients who are nonadherent to treatment have lower disease relapse and readmission rates when prescribed a LAI, compared to oral antipsychotics. Despite the reported advantages of LAIs, their prescription rates in clinical settings remain low. This pilot study aimed to determine the pattern of LAI prescription in psychiatric inpatients of a teaching community hospital in Brooklyn, New York. Methods A retrospective review of the charts of patients discharged from the psychiatric units of the hospital from September 1, 2017, through September 30, 2017, was conducted. Frequencies and proportions for demographic and disease-related characteristics were calculated. Pertinent continuous variables were recoded into categorical variables. Chi-square-tests or Fisher's exact tests were performed for categorical variables. The one-sample Shapiro-Wilk test (for sample size < 50) was used to check for the normality of distribution of continuous variables. Statistical significance was defined as p ≤ 0.05. Results Forty-three (70%) of the patients discharged from the inpatient unit during the study period had SSD and were eligible for a LAI. Their ages ranged from 20 to 71 years (mean = 41 years), and more than two-thirds were male. Less than half of the eligible patients (n = 19; 44%) were prescribed a LAI, most of whom were male (n=16; 84%). An association between age group (patients aged 41 years or younger) and LAI use was observed (p < 0.05), while gender, employment status, living arrangement, length of hospital stay, recent hospitalization, and cooccurring substance use disorder were not. Conclusion LAI prescription rate at the inpatient psychiatric unit of the hospital was marginally higher than those reported in most studies. Age appears to influence LAI use during the study period. Initiatives that increase LAI prescription rate for all eligible patients admitted to inpatient psychiatric unit should be encouraged.
背景患有精神分裂症谱系障碍(SSD)的个体通常在教育、职业和心理社会功能方面受到严重损害。长效注射抗精神病药物(LAIs)在SSD患者治疗中的临床益处已得到充分证实。与口服抗精神病药物相比,不坚持治疗的SSD患者在服用LAI时疾病复发率和再入院率较低。尽管报道了LAI的优势,但其在临床环境中的处方率仍然很低。这项试点研究旨在确定纽约布鲁克林一家教学社区医院精神病住院患者的LAI处方模式。方法对2017年9月1日至9月30日该院精神科出院患者的病历进行回顾性分析。计算人口统计学和疾病相关特征的频率和比例。相关的连续变量被重新编码为分类变量。对分类变量进行卡方检验或Fisher精确检验。单样本Shapiro-Wilk检验(样本量<50)用于检查连续变量分布的正态性。统计学显著性定义为p≤0.05。结果研究期间,43名(70%)出院患者患有SSD,符合LAI条件。他们的年龄从20岁到71岁不等(平均41岁),超过三分之二的人是男性。不到一半的符合条件的患者(n=19;44%)被开具了LAI,其中大多数是男性(n=16;84%)。年龄组(41岁或以下的患者)与LAI使用之间存在相关性(p<0.05),而性别、就业状况、生活安排、住院时间、近期住院时间和共同发生的物质使用障碍则没有。结论该院精神科住院患者的LAI处方率略高于大多数研究报告。在研究期间,年龄似乎会影响LAI的使用。应鼓励为所有入住精神科住院的符合条件的患者提高LAI处方率的举措。
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引用次数: 7
Marital Status Disruptions and Internalizing Disorders of Children. 婚姻状况、破裂与儿童内化障碍。
Pub Date : 2019-06-09 eCollection Date: 2019-01-01 DOI: 10.1155/2019/4634967
Jordyn T Wallenborn, Gregory Chambers, Elizabeth Lowery, Saba W Masho

Marital disruption (i.e., separation or divorce) impacts an estimated 40-50% of married couples. Previous research has shown that marital disruption results in negative health outcomes for children and adolescents. Our study aims to investigate the relationship between marital disruptions and internalizing disorders of children in a prospective cohort. Comparisons between marital status groups at each time point showed a significant difference in CBCL score between children in married and unmarried families at 3 years of age, with children in unmarried families having a 0.10 higher standardized CBCL score (95% CI: 0.09-0.12; p<.0001). Differences in CBCL score by marital status were not significant at 5 and 9 years after adjusting for confounders. Parental marital status is associated with an increased CBCL internalizing behavior score at 3 years of age, but the association disappears at later time points.

婚姻破裂(即分居或离婚)影响了大约40-50%的已婚夫妇。先前的研究表明,婚姻破裂会对儿童和青少年的健康产生负面影响。本研究旨在探讨婚姻破裂与儿童内化障碍之间的关系。各时间点婚姻状况组间比较显示,已婚和未婚家庭儿童3岁时的CBCL评分有显著差异,未婚家庭儿童的标准化CBCL评分高0.10 (95% CI: 0.09-0.12;p
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引用次数: 3
期刊
Psychiatry Journal
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