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Exploration of the association between contact history, socio-cultural factors and acute deliberate self-poisoning in North Central province of Sri Lanka: a case-control study 斯里兰卡中北部省接触史、社会文化因素与急性故意自我中毒关系的病例对照研究
Pub Date : 2019-12-30 DOI: 10.4038/amj.v13i1.7660
P. Pushpakumara, W. Chandrakumara, A. Gunasekara, S. Agampodi
Background Knowledge of someone else's suicidal behaviour significantly increased the risk of similar acts. Though Sri Lanka has implemented a national policy and an action plan to prevent suicides and attempted suicides, in 1997, the number of deliberate self-harm (DSH) incidents is increasing. We conducted a case-control study to identify the precipitants and to assess the possible impact of a contact history for acute deliberate self-poisoning (DSP) in view of identifying possible interventions. Materials and Methods We interviewed two hundred DSP patients, admitted to the medical wards of Teaching Hospital Anuradhapura (THA), during June - August 2004. Patients were randomly selected from a block of two consecutively admitted consenting DSP patients and an interviewer-administered questionnaire was completed. Age and sex-matched patients, who had no history of attempted suicide, admitted to medical wards of THA were interviewed as controls. Results Majority of DSP occurred among adolescents and young adults. Conflicts within the family and simple conflicts with someone else were the triggers for the majority (n=123, 61.5%, 95% CI 58.1-64.9%) of DSP. Our study showed that DSP was common among people who had not completed primary education (OR 4.5, 95% CI 2.5-7.9, p Conclusions DSP behaviour in rural Sri Lanka seems to be a learned response of vulnerable adolescents and young adults to deal with stressful situations. An in-depth exploration of this finding is needed in order to use it as a key factor in the identification of risk groups for DSP prevention.
了解他人的自杀行为会显著增加发生类似行为的风险。虽然斯里兰卡实施了一项国家政策和一项行动计划,以防止自杀和企图自杀,但在1997年,蓄意自残事件的数量正在增加。我们进行了一项病例对照研究,以确定沉淀剂,并评估接触史对急性故意自我中毒(DSP)的可能影响,以确定可能的干预措施。材料与方法我们访问了2004年6 - 8月在阿努拉德普勒教学医院(THA)病房住院的200例DSP患者。患者从两个连续入院的同意DSP患者中随机选择,并完成访谈者管理的问卷调查。年龄和性别相匹配的无自杀未遂史的住院患者作为对照。结果主要发生在青少年和青壮年。家庭内部冲突和与他人的简单冲突是大多数DSP的触发因素(n=123, 61.5%, 95% CI 58.1-64.9%)。我们的研究表明,DSP在未完成初等教育的人群中很常见(OR 4.5, 95% CI 2.5-7.9, p)。结论:斯里兰卡农村地区的DSP行为似乎是弱势青少年和年轻人应对压力情况的一种习得性反应。需要对这一发现进行深入探索,以便将其作为识别DSP预防风险群体的关键因素。
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引用次数: 0
Prevalence of incidental thyroid carcinoma (ITC) among total thyroidectomies performed by PSU-UOR on multinodular goiters; how accurate is the diagnosis and how rational is the treatment? PSU-UOR治疗多结节性甲状腺全甲状腺切除术中偶发甲状腺癌(ITC)的发生率诊断有多准确,治疗有多合理?
Pub Date : 2018-12-27 DOI: 10.4038/amj.v12i1.7612
R. W. Seneviratne, M. Kumara, J. Kumarasinghe, R. P. Abeywicrama, P. D. Silva
Background FNAC is regarded as a accurate, safe, and economical technique in identifying thyroid cancer in Mulitnodular goiter (MNG). The aim of our study was to detect the accuracy of FNAC in detecting thyroid cancer among patients undergoing total thyroidectomy at Professorial surgical unit, Teaching Hospital-Galle (PSU-THK).  Methods Indications for total thyroidectomy at PSU-THK include Thy 3-5 on FNAC, retrosternal goiters, those presenting with symptoms suggestive of obstruction or infiltration and cosmesis. However thy1-2 are also offered depending on the situation. Patients who had undergone total thyroidectomy for MNG with FNAC reporting Thy1-2, as well as those with Thy-3 FNAC, from 1st April 2014 to 31st march 2016 were analyzed.  Results Three hundred and forty two patients completed selection criteria for the study and 299 of them were females. Forty five point six percent belonged to the 20-39 age group and 38.89% belonged to the 39-64 age group. Two hundred ad eighty-four had Thy1-2 FNAC while 58 had Thy-3. Of the Thy 1-2 group, 212 had colloid goiter on FNAC and 54 had thyroiditis. Histology revealed malignancy in 14 female patients, 9 papillary and 4 follicular. Among the 58 patients of Thy 3, 15 had confirmed malignancy with 10 papillary and 4 follicular. The policy practiced by PSU-UOR in offering total thyroidectomy to MNGs in Thy1- 2 group is justified as the study shows them to have 4.93% risk of ITC. A similarly policy of offering total thyroidectomy to all the cases with Thy3 MNGs is recommended as the requirement of a second operation is high.  Conclusion Further research need to be carried out to identify thyroid cancer in MNGs with Thy 1-3 cytology, allowing clinicians to offer total thyroidectomy for more solid indications.
背景FNAC是一种准确、安全、经济的多结节性甲状腺肿(MNG)甲状腺癌症鉴别技术。我们研究的目的是检测FNAC在接受全甲状腺切除术的患者中检测甲状腺癌症的准确性,这些患者在教授外科,教学医院-Galle(PSU-THK)。方法PSU-THK甲状腺全切除术的适应症包括FNAC上的Thy 3-5、胸骨后甲状腺肿、有梗阻或浸润症状的甲状腺肿和美容。然而,thy1-2也根据情况提供。对2014年4月1日至2016年3月31日期间接受MNG甲状腺全切除术且FNAC报告Thy1-2的患者以及Thy-3 FNAC的患者进行分析。结果342名患者完成了本研究的选择标准,其中299人为女性。45.6%属于20-39岁年龄组,38.89%属于39-64岁年龄组。在284例患者中有200例患有Thy1-2FNAC,58例患有Thy-3。Thy1-2组中,212例经FNAC检查为胶质性甲状腺肿,54例为甲状腺炎。组织学检查显示14例女性患者为恶性肿瘤,其中9例为乳头状,4例为滤泡状。在58例Thy 3患者中,15例确诊为恶性肿瘤,其中10例为乳头状,4例为滤泡状。PSU-OR为Thy1-2组MNG提供甲状腺全切除术的政策是合理的,因为研究表明他们有4.93%的ITC风险。由于第二次手术的要求很高,建议采取类似的政策,为所有Thy3 MNG患者提供甲状腺全切除术。结论需要进一步研究Thy 1-3细胞学检测MNGs中甲状腺癌症的鉴别,为临床医生提供更可靠的甲状腺全切除术指征。
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引用次数: 0
Analysis of gaps in the correct diagnosis of leishmaniasis at primary care level; socio-demographic and environmental risk factors of leishmaniasis transmission in Anuradhapura 分析初级保健水平对利什曼病正确诊断的差距;阿努拉德普拉利什曼病传播的社会人口和环境危险因素
Pub Date : 2018-12-27 DOI: 10.4038/amj.v12i1.7638
H. Weerakoon, R. Ranawaka, J. Warnasekara, P. Bandara
Background The leishmaniasis is an emerging health problem in dry zone of Sri Lanka. The multiplicity of factors involved in the transmission of leishmaniasis constitutes a challenge to its control. Knowledge of such factors may contribute to identify the control strategies. Although Medical officers have been given training on leishmaniasis, still patients with leishmaniasis had been diagnosed incorrectly. Aim of the study was to analysis of the diagnosis pattern of leishmaniasis patients by the primary care medical officers and to identify potential socio demographic and environmental risk factors of leishmaniasis transmission. Methods A descriptive cross sectional study conducted among the leishmaniasis patients attending to the Dermatology clinic, Teaching Hospital Anuradhapura during November 2015 to November 2016 using interviewer administered questionnaire.  Results  The study sample was 300 leishmaniasis patients .Male to female ratio was 2:1.The commonest affected age group was 20 to 40 years .Lesser number (33%) had heard about leishmaniasis. Nearly one forth (23%) of patients had been diagnosed incorrectly at the primary health care level. Nearly 50%of patients got leishmaniasis due to occupation related activities. Most (75%) of patients had paddy fields, large number of Banana bushes, Manna bushes and large wild area near their residence. Nearly 50% of patients had water channel near their residence. All most all (96%) patients use bed nets. Conclusion Nearly one forth of patients missed diagnosis at the primary health care level. Paddy fields, Banana bushes, Manna bushes, large wild area and water channels close to residence may play role in leishmaniasis transmission.
背景:利什曼病是斯里兰卡干旱地区新出现的卫生问题。利什曼病传播涉及多种因素,对控制该病构成挑战。了解这些因素可能有助于确定控制策略。尽管对医务人员进行了关于利什曼病的培训,但利什曼病患者仍被错误诊断。本研究的目的是分析初级保健医务人员对利什曼病患者的诊断模式,并确定潜在的利什曼病传播的社会人口和环境危险因素。方法对2015年11月至2016年11月在阿努拉德拉普勒教学医院皮肤科门诊就诊的利什曼病患者进行描述性横断面研究。结果研究对象为300例利什曼病患者,男女比例为2:1。最常见的发病年龄组为20 ~ 40岁。较少的人(33%)听说过利什曼病。近四分之一(23%)的患者在初级卫生保健一级被错误诊断。近50%的患者因职业相关活动而患利什曼病。大多数(75%)患者住所附近有水田、大量香蕉灌木、甘露灌木和大片野生区域。近50%的患者住所附近有水道。几乎所有(96%)患者都使用蚊帐。结论近四分之一的患者在初级卫生保健阶段漏诊。稻田、香蕉灌木、甘露灌木、大面积野生区域和靠近居民区的水道可能是利什曼病传播的重要渠道。
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引用次数: 2
Thyrotoxicosis presenting with pancytopenia: a case report 甲状腺毒症伴全血细胞减少1例
Pub Date : 2018-12-27 DOI: 10.4038/amj.v12i1.7633
P. Premathilake, W. Kularatne, S. D. N. Senadhira
Thyrotoxicosis can present with a wide array of clinical manifestations, among which pancytopenia is a rare entity. The disease itself, as well the treatment, can result in pancytopenia which makes the diagnosis more difficult and crucial. The mechanisms underlying are poorly understood currently. Antithyroid drugs which are well known to produce cytopenias as a side effect can safely be implemented in the management. Pancytopenia of thyrotoxicosis should completely reverse with the establishment of euthyroid state. We report a rare case of thyrotoxicosis presenting with pancytopenia which completely resolved with antithyroid treatment.
甲状腺毒性病可表现出广泛的临床表现,其中全血细胞减少症是一种罕见的疾病。这种疾病本身以及治疗都会导致全血细胞减少症,这使得诊断更加困难和关键。目前对其背后的机制了解甚少。众所周知,抗甲状腺药物会产生细胞减少症,这是一种副作用,可以安全地在管理中使用。甲状腺毒症的全血细胞减少症应随着甲状腺功能正常状态的建立而完全逆转。我们报告了一例罕见的甲状腺毒症,表现为全血细胞减少,经抗甲状腺药物治疗后完全消失。
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引用次数: 1
Mutlicentric Castleman’s disease presenting in a young patient 多中心卡斯尔曼氏病出现在一名年轻患者身上
Pub Date : 2018-12-27 DOI: 10.4038/amj.v12i1.7654
M. Boralessa, A. H. N. Fernando
Multicentric Castleman's disease (MCD) is a rare lymphoprofilerative disease and Its presentation in a young age population is unusual. Here, we report the case of a 28 year old Sri Lankan, male who was evaluated for lower limb edema and sensory type neuropathy along with skin thickening and pigmentation. He was found to have generalized lymphadenopathy and hepatosplenomegaly. His investigations revealed evidence of demyelinating type sensory- motor polyneuropathy, pulmonary hypertension, hypothyroidism. However studies conducted for HIV viruses and monoclonal gammopathy were negative. An excision biopsy of an Inguinal lymph node of his right side axila revealed changes supportive of a diagnosis of multicentric Castleman's disease. Despite being a rare disease and even rarer in a young population, diagnosis of MCD/POEMS syndrome should be suspected in patients' presenting with similar features described above. MCD is associated with many malignancies and has poor prognosis.
多中心Castleman病(MCD)是一种罕见的淋巴细胞增生性疾病,其在年轻人群中的表现是不寻常的。在这里,我们报告一个28岁的斯里兰卡男性病例,他因下肢水肿和感觉型神经病变以及皮肤增厚和色素沉着而被评估。他被发现有全身性淋巴结病和肝脾肿大。他的检查显示脱髓鞘型感觉-运动多神经病变,肺动脉高压,甲状腺功能减退。然而,对HIV病毒和单克隆γ病进行的研究均为阴性。右侧腋窝腹股沟淋巴结的活检切除显示了支持多中心Castleman病诊断的变化。尽管MCD/POEMS是一种罕见的疾病,在年轻人群中更为罕见,但应在患者出现上述相似特征时怀疑其诊断。MCD与许多恶性肿瘤相关,预后较差。
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引用次数: 0
Teaching life skills through arts; an option for adolescent health promotion in resource poor settings 通过艺术教授生活技能;在资源贫乏环境中促进青少年健康的一种选择
Pub Date : 2018-12-27 DOI: 10.4038/amj.v12i1.7647
G. Amarasinghe
Background Life skills prepare teenagers to face challenges in daily life. This study describes a novel art based life skills training programme that takes vulnerabilities and available opportunities for individual participant into account, to promote health of adolescents in resource poor settings. Methods A 2 hour session with two drawing activities followed by facilitated discussion was conducted for 42 students aging 13 to 16 years at a rural school. Drawings of the students were observed and themes were identified. Observation memos were documented during discussions and drawing activities. Anonymous written Feedback obtained at the end was analyzed thematically and triangulated with observations. Results Enthusiastic participation across all age groups was observed. The programme was described as interesting, clear and motivating. Students getting an understanding on applicability of life skills to overcome their personal challenges were observed during discussion and through feedback. Conclution The programme requires minimum resources and can provide an individualized active life skill learning opportunity to adolescents in low resource settings. Long term outcomes need to be assessed objectively.
生活技能帮助青少年应对日常生活中的挑战。这项研究描述了一种新的基于艺术的生活技能培训方案,该方案考虑到个体参与者的脆弱性和现有机会,以促进资源贫乏环境中青少年的健康。方法对一所农村学校42名13 ~ 16岁的学生进行了2小时的绘画活动,并进行了促进讨论。观察学生的绘画并确定主题。在讨论和绘图活动中记录观察备忘录。最后获得的匿名书面反馈进行了主题分析,并与观察结果进行了三角测量。结果观察到所有年龄组的参与热情。该计划被描述为有趣、清晰和激励。通过讨论和反馈,学生们了解了生活技能在克服个人挑战方面的适用性。该方案所需资源最少,可为资源匮乏地区的青少年提供个性化的积极生活技能学习机会。需要客观地评估长期结果。
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引用次数: 0
Mental health of children from a war affected border village: a cross sectional comparative study 受战争影响的边境村庄儿童的心理健康:横断面比较研究
Pub Date : 2018-12-27 DOI: 10.4038/amj.v12i1.7646
P. Pushpakumara, W. Chandrakumara
Background Sri Lankan government had a war against terrorism for thirty years in North and East of Sri Lanka. There were villages in the North-East border that the LTTE held territory and the community living in those villages faced frequent attacks during those three decades. The present study was conducted to compare the mental health of children in a war affected border village, with the mental health of same aged children from a village not directly affected by the war.   Methods Grade 8 and 9 students (n=148) from a government school were selected as subjects and a self-administered questionnaire and the validated Sinhalese version of the Strengths and Difficulties Questionnaire (SDQ) were completed. Age matched 138 students were selected as the comparison group, from an area which is socioeconomically similar but not affected by the war as a border village. Same questionnaires were completed by the comparison group.   Results Subject group consisted of 76 (51%) males and 72 (49%) females. Age ranged from 12-16 years (median 14, IQR 13-14). Majority (n=85, 57.0%) of children living in the border village experienced some kind of an extremely terrifying incident related to the war. Nearly one fifth (n=26, 17.6%) living in the border village, had lost at least one immediate family member due to terrorist attacks. Majority of the border village children (n=94, 63.5%) believed that the war produced a significant negative impact on their lives. Children living in the border village showed 2.5 fold excess risk for a mental health problem (OR 2.5, 95% CI 1.4 to 4.5.   Living in a border village carried 3 times excess risk for conduct problems (OR 3.1, 95% CI 1.6 to 6.0). Children living in the border village showed 2 fold excess risk for peer relationship problems (OR 1.9, 95% CI 1.1 to 3.2). Living in a border village carried 2 fold excess risk for hyperactivity/inattention problems (OR 2.3, 95% CI 1.2 to 4.2).  Conclusions Majority of the children living in border village reported different exposures related to the civil war that can cause considerable and long-lasting psychological impact. Children from the border village had a significantly higher risk of showing borderline abnormal values on the SDQ, compared to children not from a border village. It is probable that this is due to the effect of war and its impact on the mental health of the children of the border village.
斯里兰卡政府在斯里兰卡北部和东部进行了长达30年的反恐战争。东北边界的一些村庄是猛虎组织控制的领土,在这三十年中,居住在这些村庄的社区经常受到攻击。本研究旨在比较受战争影响的边境村庄儿童的心理健康状况与未受战争直接影响的村庄同龄儿童的心理健康状况。方法选取某公办学校八、九年级学生148名,分别填写自填问卷和有效的僧伽罗语优势与困难问卷(SDQ)。年龄匹配的138名学生作为对照组,他们来自一个社会经济相似但未受战争影响的边境村庄。对照组也完成了同样的问卷调查。结果受试者组男性76例(51%),女性72例(49%)。年龄12-16岁(中位14岁,IQR 13-14岁)。居住在边境村庄的大多数儿童(n=85, 57.0%)经历了某种与战争有关的极其可怕的事件。近五分之一(n=26, 17.6%)居住在边境村庄,因恐怖袭击失去了至少一名直系亲属。大多数边境村儿童(n=94, 63.5%)认为战争对他们的生活产生了显著的负面影响。生活在边境村庄的儿童出现精神健康问题的风险高出2.5倍(OR 2.5, 95% CI 1.4至4.5)。生活在边境村庄的行为问题风险高出3倍(OR 3.1, 95% CI 1.6 - 6.0)。生活在边境村庄的儿童出现同伴关系问题的风险高出2倍(OR 1.9, 95% CI 1.1 - 3.2)。居住在边境村庄的儿童出现多动/注意力不集中问题的风险高出2倍(OR 2.3, 95% CI 1.2 - 4.2)。大多数生活在边境村庄的儿童报告了与内战有关的不同暴露,这些暴露可能造成相当大和长期的心理影响。来自边境村庄的儿童与非边境村庄的儿童相比,在SDQ上显示边缘性异常值的风险明显更高。这很可能是由于战争的影响及其对边境村庄儿童心理健康的影响。
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引用次数: 0
Is Cancer Screening a Priority among Adult Females in Sri Lanka? 癌症筛查是斯里兰卡成年女性的优先事项吗?
Pub Date : 2018-09-18 DOI: 10.4038/AMJ.V11I1.7639
Y. Warnasekara, M. K. Gamakumbura, S. D. Konthota, L. Liyanage, Bad Lakpriya, S. Agampodi
We assessed the use of well women clinics (WWC) screening services for cervical and breast cancer prevention in a sample of females attending the largest religious festival in Sri Lanka. Of the 3,116 women studied, 2, 874(92.2%) were aware on breast cancer and 2, 609(83.7%) on cervical carcinoma. Of them only 1,895 (60.8%) were aware of the WWC services, but only 578 (18.5%) had ever used the services. Of the 217 professionals or associate professionals in the study sample, 190 (87.6%) were aware of the WWC compared to only 58.8% among the 2,899 women falling under the categories of other occupations and housewives. Clinic attendance was also significantly higher amongst professionals and associate professionals compared to women in other occupational categories and housewives (40.1% versus 16.9%). Use of cancer screening services are low and new strategies needed to improve the secondary prevention of these cancers in Sri Lanka.
我们在斯里兰卡参加最大宗教节日的女性样本中评估了健康女性诊所(WWC)筛查服务在预防宫颈癌和乳腺癌方面的使用情况。在研究的3116名女性中,2874名(92.2%)了解癌症,2609名(83.7%)了解宫颈癌。其中只有1895人(60.8%)知道WWC服务,但只有578人(18.5%)使用过这些服务。在研究样本中的217名专业人员或副专业人员中,190人(87.6%)知道WWC,而在其他职业和家庭主妇类别的2899名女性中,这一比例仅为58.8%。与其他职业类别的妇女和家庭主妇相比,专业人员和准专业人员的就诊率也显著较高(40.1%对16.9%)。癌症筛查服务的使用率较低,斯里兰卡需要采取新的策略来改善这些癌症的二级预防。
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引用次数: 1
A rare presentation of Guillain -Barre syndrome: Pharyngeal-cervical-brachial variant 格林-巴利综合征的罕见表现:咽颈臂变异
Pub Date : 2018-09-17 DOI: 10.4038/amj.v11i1.7626
Mohamed Nadheem
Guillain-Barre syndrome is characterized by acute onset symmetrical , generalized, ascending weakness with areflexia. It has wide variety of subtypes according to the involvement of muscle and nerve groups. We describe a case of 70 year old lady developing a rare form of GBS, the pharyngeal-cervical-brachial variant of the disease.
格林-巴利综合征的特点是急性发作的对称性、全身性、上升性虚弱伴灵活性减退。根据肌肉和神经组的参与程度,它有各种各样的亚型。我们描述了一例70岁的妇女发展为一种罕见的GBS,咽颈臂变异性疾病。
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引用次数: 1
Lung function assessment in preschool children; a review of the utility of basic spirometry, interrupter technique and forced oscillation technique 学龄前儿童肺功能评价基本肺活量测定法、中断技术和强制振荡技术的应用综述
Pub Date : 2018-09-06 DOI: 10.4038/AMJ.V11I1.7641
S. Rajapakse, D. Yasaratne, L. Amarasiri
Objective lung function assessment in preschool children is a challenge; the mechanics of the lungs are changing rapidly with advancing age and maturation, the population is too old to ethically justify routine sedation prior to lung function assessment, as in infants, and also, they are too young to be able to focus sufficiently and perform elaborate respiratory manoeuvers required by commonly used lung function tests in older children and adults. But, clinically, a clear evidence based demarcation between isolated non-significant episodes of respiratory symptoms and pathognomonic symptoms is vital for the management. Even though many different lung function techniques are commonly used in the assessment of preschool children, the purpose of this review is to evaluate three commonly used pulmonary function tests, viz. basic spirometry, interrupter technique and forced oscillation technique in order to assess their usefulness in preschool children. We conclude that contrary to common misbelief, ample evidence exists that preschool children are capable of performing lung function tests. Basic spirometry, which stood the test of time, remains one of the most commonly used lung function tests. The interrupter technique and the forced oscillation techniques are quickly gathering reputation as reliable alternatives for lung function assessment in preschool children, especially due to the minimal co-operation required from the subject and the versatility of the test. These techniques will enable definitive diagnosis, assessment of severity and the therapeutic response of multiple, complex and often challenging clinical respiratory conditions to enable efficient management
客观评价学龄前儿童肺功能是一个挑战;随着年龄的增长和成熟,肺的机制正在迅速变化,人口年龄太大,在肺功能评估之前常规镇静在伦理上是合理的,如在婴儿中,而且,他们太年轻,不能充分集中注意力,不能执行在较大的儿童和成人中常用的肺功能测试所需的复杂的呼吸操作。但是,在临床上,明确区分孤立的非显著呼吸道症状发作和病状症状对于治疗至关重要。尽管许多不同的肺功能技术通常用于学龄前儿童的评估,但本综述的目的是评估三种常用的肺功能测试,即基本肺活量测定法、中断技术和强迫振荡技术,以评估它们在学龄前儿童中的实用性。我们得出结论,与普遍的误解相反,有充分的证据表明,学龄前儿童有能力进行肺功能测试。基本肺活量测定法经受住了时间的考验,仍然是最常用的肺功能测试之一。中断技术和强迫振荡技术作为评估学龄前儿童肺功能的可靠替代方案,正迅速获得声誉,特别是由于受试者的最小合作要求和测试的多功能性。这些技术将能够明确诊断,评估严重程度和治疗反应的多种,复杂的,往往具有挑战性的临床呼吸条件,使有效的管理
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引用次数: 1
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Anuradhapura Medical Journal
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