Although it has clinical features that overlap with Kawasaki disease (KD) and toxic shock syndrome (TSS), an intense inflammatory storm distinguishes multisystem inflammatory syndrome in children (MIS-C) from KD and TSS. We report four children with laboratory evidence of severe acute respiratory syndrome - coronavirus - 2 (SARS-CoV-2) infection presenting with persistent fever, mucocutaneous signs, and raised inflammatory markers associated with remarkable multi-organ involvement, particularly that of the gastrointestinal and cardiovascular systems. All of them responded well to immunosuppressive therapy, including intravenous immunoglobulin and methylprednisolone. The distinguishing clinical characteristics found in MIS-C include the age of the child, gastrointestinal symptoms, and hypotension without coronary involvement. Immediate medical care is needed for a better outcome, and most children need management in an intensive care unit.
{"title":"COVID-19 related multisystem inflammatory syndrome in children (MIS-C): a case series from a tertiary care hospital in Sri Lanka","authors":"M. Jayasinghe, Manel Panapitiya","doi":"10.4038/amj.v16i2.7714","DOIUrl":"https://doi.org/10.4038/amj.v16i2.7714","url":null,"abstract":"Although it has clinical features that overlap with Kawasaki disease (KD) and toxic shock syndrome (TSS), an intense inflammatory storm distinguishes multisystem inflammatory syndrome in children (MIS-C) from KD and TSS. We report four children with laboratory evidence of severe acute respiratory syndrome - coronavirus - 2 (SARS-CoV-2) infection presenting with persistent fever, mucocutaneous signs, and raised inflammatory markers associated with remarkable multi-organ involvement, particularly that of the gastrointestinal and cardiovascular systems. All of them responded well to immunosuppressive therapy, including intravenous immunoglobulin and methylprednisolone. The distinguishing clinical characteristics found in MIS-C include the age of the child, gastrointestinal symptoms, and hypotension without coronary involvement. Immediate medical care is needed for a better outcome, and most children need management in an intensive care unit.","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43983764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Solangaarachchi, D. Subasinghe, M. Suraweera, N. Suraweera, N. Dilshani, S. Senadheera
Most Hibiscus tea are made with Hibiscus rosasinensis and are expensive. Although these tea are marketed indicating hypoglycemic effects, scientific data are lacking on the effect of H. rosasinensis on humans. The objective of the study was to determine the effect of home-made water extract of H. rosasinensis flower (HRWE) as a tea on post-prandial blood sugar level (PPBS) of healthy individuals compared to green tea (GT) and commercially available Hibiscus tea (CHT–H.rosasinensis+Rosehip). Fasting and PPBS [after consuming a standard diet (StD=1045Kcal), StD+GT, StD+CHT and StD+HRWE on separate days] at 15, 30, 45, 60 and 120 minutes of healthy volunteers (n=14) were measured
{"title":"Home-made Hibiscus rosasinensis tea on post-prandial blood glucose level and blood pressure: An interventional study","authors":"M. Solangaarachchi, D. Subasinghe, M. Suraweera, N. Suraweera, N. Dilshani, S. Senadheera","doi":"10.4038/amj.v16i2.7705","DOIUrl":"https://doi.org/10.4038/amj.v16i2.7705","url":null,"abstract":"Most Hibiscus tea are made with Hibiscus rosasinensis and are expensive. Although these tea are marketed indicating hypoglycemic effects, scientific data are lacking on the effect of H. rosasinensis on humans. The objective of the study was to determine the effect of home-made water extract of H. rosasinensis flower (HRWE) as a tea on post-prandial blood sugar level (PPBS) of healthy individuals compared to green tea (GT) and commercially available Hibiscus tea (CHT–H.rosasinensis+Rosehip). Fasting and PPBS [after consuming a standard diet (StD=1045Kcal), StD+GT, StD+CHT and StD+HRWE on separate days] at 15, 30, 45, 60 and 120 minutes of healthy volunteers (n=14) were measured","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47314107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dilini Chandrananda, Anne Benarrin, Eranga Chandrarathne, Supun Chanaka, A. Begam, H. Weerakoon
{"title":"Does English literacy and learning style affect the 2nd MBBS exam performance of medical undergraduates?: a descriptive cross-sectional study","authors":"Dilini Chandrananda, Anne Benarrin, Eranga Chandrarathne, Supun Chanaka, A. Begam, H. Weerakoon","doi":"10.4038/amj.v16i2.7721","DOIUrl":"https://doi.org/10.4038/amj.v16i2.7721","url":null,"abstract":"","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45298960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Narasinghe, C. Sarathchandra, H. Senanayake, P. Weerawansa
magnesium revealed rhythm with u waves. Abstract Hypokalemic periodic paralysis is a rare clinical syndrome characterized by low serum potassium and severe muscle weakness. The aetiology can be primary idiopathic or secondary to other disorders such as thyroid dysfunction and renal tubular acidosis. Hypokalemic periodic paralysis with distal renal tubular acidosis (RTAd) is seen in a cluster of the population in the North-central province of Sri Lanka particularly in association with Southeast Asian Ovalocytosis (SEAO). Here, we report the first case of severe respiratory muscle paralysis in a patient having RTAd with severe hypokalemia with associated SEAO from the North Central province, Sri Lanka.
{"title":"Respiratory muscle paralysis in a patient with hypokalemia associated with Southeast Asian ovalocytosis: A case report","authors":"S. Narasinghe, C. Sarathchandra, H. Senanayake, P. Weerawansa","doi":"10.4038/amj.v16i2.7681","DOIUrl":"https://doi.org/10.4038/amj.v16i2.7681","url":null,"abstract":"magnesium revealed rhythm with u waves. Abstract Hypokalemic periodic paralysis is a rare clinical syndrome characterized by low serum potassium and severe muscle weakness. The aetiology can be primary idiopathic or secondary to other disorders such as thyroid dysfunction and renal tubular acidosis. Hypokalemic periodic paralysis with distal renal tubular acidosis (RTAd) is seen in a cluster of the population in the North-central province of Sri Lanka particularly in association with Southeast Asian Ovalocytosis (SEAO). Here, we report the first case of severe respiratory muscle paralysis in a patient having RTAd with severe hypokalemia with associated SEAO from the North Central province, Sri Lanka.","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43796879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
objective was to determine activity among undergraduate medical students using smartphone technology. Abstract With the advancement of technology, smartphones have become a widely available tool in day-to-day activities. However, the feasibility of using this technology daily 45 medical males). daily steps count a range of 2132 to 12709. of daily step count lower step count. step counts
{"title":"Smartphone technology to monitor physical activity among medical students and its association with mental distress","authors":"Yasodha Dissanayake, J. Warnasekara, S. Agampodi","doi":"10.4038/amj.v16i2.7702","DOIUrl":"https://doi.org/10.4038/amj.v16i2.7702","url":null,"abstract":"objective was to determine activity among undergraduate medical students using smartphone technology. Abstract With the advancement of technology, smartphones have become a widely available tool in day-to-day activities. However, the feasibility of using this technology daily 45 medical males). daily steps count a range of 2132 to 12709. of daily step count lower step count. step counts","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":"441 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41283013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ensuring responsible conduct of research and publications in Sri Lankan context: an eye-opener","authors":"Anjana Silva, K. Weerakoon","doi":"10.4038/amj.v16i2.7731","DOIUrl":"https://doi.org/10.4038/amj.v16i2.7731","url":null,"abstract":"","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44658436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Amarakoon, Supun Wedasingha, Isuru Sandakelum, Janith Chandrakumara, Anjana Silva
{"title":"Myocarditis and severe neuromuscular paralysis following a suspected Common krait (Bungarus caeruleus) envenoming in a child: A case report","authors":"G. Amarakoon, Supun Wedasingha, Isuru Sandakelum, Janith Chandrakumara, Anjana Silva","doi":"10.4038/amj.v16i1.7713","DOIUrl":"https://doi.org/10.4038/amj.v16i1.7713","url":null,"abstract":"","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44086422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Jayasooriya, Jerrard Fernando, Chatura Rathnayake
{"title":"Abnormalities in MRI brain in Sri Lankan children with epilepsy: A descriptive study","authors":"D. Jayasooriya, Jerrard Fernando, Chatura Rathnayake","doi":"10.4038/amj.v16i1.7703","DOIUrl":"https://doi.org/10.4038/amj.v16i1.7703","url":null,"abstract":"","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48547386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statin-induced autoimmune necrotizing myopathy: A case report","authors":"Ranga Chamara, K. Jayasinghe","doi":"10.4038/amj.v16i1.7699","DOIUrl":"https://doi.org/10.4038/amj.v16i1.7699","url":null,"abstract":"","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43106508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Weerakoon, Hasantha Banduwardana, R. Ranawaka, P. Bandara, U. S. Kumara, Nimal Ariyarathna, J. Warnasekara
{"title":"Socio-demographic factors, treatment-seeking behaviours and common clinical presentations of leprosy patients in Anuradhapura, Sri Lanka","authors":"H. Weerakoon, Hasantha Banduwardana, R. Ranawaka, P. Bandara, U. S. Kumara, Nimal Ariyarathna, J. Warnasekara","doi":"10.4038/amj.v16i1.7669","DOIUrl":"https://doi.org/10.4038/amj.v16i1.7669","url":null,"abstract":"","PeriodicalId":30600,"journal":{"name":"Anuradhapura Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70099414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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