Nabin Kumar Chaudhary, J. Giri, R. Gyawali, Prabhat Ranjan Pokharel
Regarding the relationship between the size of the pharynx and several sagittal skeletal malocclusions and patterns of growth, contradictory findings have been documented. The intent of this research was to analyze the size of the pharynx in various sagittal malocclusions and growth patterns in the Nepalese population. An analytic cross-sectional research was undertaken on patients who attended the Orthodontics Division of BPKIHS. A total of 135 patients’ lateral cephalometric radiographs were gathered. Medians and interquartile ranges of pharyngeal widths according to McNamara airway analysis and Arnett/Gunson FAB airway analysis adapted by Santiago et al. in different skeletal malocclusions and growth patterns were compared. There was not any discernible statistically noteworthy variation within the upper pharynx size, lower pharyngeal width, nasopharyngeal width (WNP), oropharyngeal width, hypopharyngeal width (WHP), and deep pharyngeal width (WDP) in different skeletal malocclusions. A statistically significant variation was discovered in nasopharyngeal size (P = 0.010), hypopharyngeal size (P = 0.027), and deep pharyngeal size (P < 0.001) in various patterns of growth, i.e. hypodivergent versus normodivergent, and in hypodivergent versus hyperdivergent, not in normodivergent versus hyperdivergent group of patients. There was not anything statistically noteworthy variation in the pharyngeal widths of the participants with respect to the various skeletal malocclusions. WNP, WHP, and WDP showed a statistically significant variation between hypodivergent versus normodivergent and hypodivergent versus hyperdivergent growth patterns.
{"title":"Pharyngeal width comparison in different skeletal malocclusions and growth patterns of Nepalese population","authors":"Nabin Kumar Chaudhary, J. Giri, R. Gyawali, Prabhat Ranjan Pokharel","doi":"10.4103/jorr.jorr_63_23","DOIUrl":"https://doi.org/10.4103/jorr.jorr_63_23","url":null,"abstract":"\u0000 \u0000 Regarding the relationship between the size of the pharynx and several sagittal skeletal malocclusions and patterns of growth, contradictory findings have been documented.\u0000 \u0000 \u0000 \u0000 The intent of this research was to analyze the size of the pharynx in various sagittal malocclusions and growth patterns in the Nepalese population.\u0000 \u0000 \u0000 \u0000 An analytic cross-sectional research was undertaken on patients who attended the Orthodontics Division of BPKIHS.\u0000 \u0000 \u0000 \u0000 A total of 135 patients’ lateral cephalometric radiographs were gathered. Medians and interquartile ranges of pharyngeal widths according to McNamara airway analysis and Arnett/Gunson FAB airway analysis adapted by Santiago et\u0000 al. in different skeletal malocclusions and growth patterns were compared.\u0000 \u0000 \u0000 \u0000 There was not any discernible statistically noteworthy variation within the upper pharynx size, lower pharyngeal width, nasopharyngeal width (WNP), oropharyngeal width, hypopharyngeal width (WHP), and deep pharyngeal width (WDP) in different skeletal malocclusions. A statistically significant variation was discovered in nasopharyngeal size (P = 0.010), hypopharyngeal size (P = 0.027), and deep pharyngeal size (P < 0.001) in various patterns of growth, i.e. hypodivergent versus normodivergent, and in hypodivergent versus hyperdivergent, not in normodivergent versus hyperdivergent group of patients.\u0000 \u0000 \u0000 \u0000 There was not anything statistically noteworthy variation in the pharyngeal widths of the participants with respect to the various skeletal malocclusions. WNP, WHP, and WDP showed a statistically significant variation between hypodivergent versus normodivergent and hypodivergent versus hyperdivergent growth patterns.\u0000","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"9 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. D’souza, Suresh Chari, S. Nagda, Chinmay Shah, Fhelen D. da Costa
Lack of professional integrity among dental students can greatly impact the safety of future patients. Currently, there are no established learning outcomes for dental professionalism. The aim of the study is to assess the perceptions of Indian educators (DE) and residents (DR) towards the attributes and methods to learn/teach dental professionalism. A cross-sectional descriptive study was conducted among Indian DE and DR from April 1, 2022, to July 31, 2022. A 31-item questionnaire was developed to evaluate the demographic data, perceptions of learning/teaching methods, and attributes of professionalism. The sample size was calculated to 446 subjects. Descriptive statistics were carried out. Of the 428 participants, 287 were DE and 141 were DR. Most participants are aware of the attributes and have a positive attitude toward professionalism. Role modeling and mentoring were the most effective ways to learn professionalism. About 97.9% of DE and 97.9% of DR felt it was important to teach dental students about professionalism. About 85.7% of DE and 73% of DR felt the need for an additional program in the current BDS curriculum. Most participants selected contact with role model teachers, clinical experience with patients, and discussion with peers as methods by which they learned dental professionalism. The majority of the participants are aware and have a positive attitude toward dental professionalism.
{"title":"Perception towards professionalism among Indian dental educators and residents – A descriptive study","authors":"K. D’souza, Suresh Chari, S. Nagda, Chinmay Shah, Fhelen D. da Costa","doi":"10.4103/jorr.jorr_65_23","DOIUrl":"https://doi.org/10.4103/jorr.jorr_65_23","url":null,"abstract":"\u0000 \u0000 Lack of professional integrity among dental students can greatly impact the safety of future patients. Currently, there are no established learning outcomes for dental professionalism.\u0000 \u0000 \u0000 \u0000 The aim of the study is to assess the perceptions of Indian educators (DE) and residents (DR) towards the attributes and methods to learn/teach dental professionalism.\u0000 \u0000 \u0000 \u0000 A cross-sectional descriptive study was conducted among Indian DE and DR from April 1, 2022, to July 31, 2022. A 31-item questionnaire was developed to evaluate the demographic data, perceptions of learning/teaching methods, and attributes of professionalism. The sample size was calculated to 446 subjects. Descriptive statistics were carried out.\u0000 \u0000 \u0000 \u0000 Of the 428 participants, 287 were DE and 141 were DR. Most participants are aware of the attributes and have a positive attitude toward professionalism. Role modeling and mentoring were the most effective ways to learn professionalism. About 97.9% of DE and 97.9% of DR felt it was important to teach dental students about professionalism. About 85.7% of DE and 73% of DR felt the need for an additional program in the current BDS curriculum. Most participants selected contact with role model teachers, clinical experience with patients, and discussion with peers as methods by which they learned dental professionalism.\u0000 \u0000 \u0000 \u0000 The majority of the participants are aware and have a positive attitude toward dental professionalism.\u0000","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"22 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sclerostin is a glycoprotein predominantly released by specialized bone-forming cells (osteocytes). It serves as a principal inhibitor of osteogenesis and plays a key act in modulating the metabolism of alveolar bone. Sclerostin is shown to contribute to the occurrence of periodontitis by regulating the remodeling of the alveolar bone. A monoclonal antibody which antagonizes sclerostin has become extremely useful for osteoanabolic therapies. Romosozumab is an Food and Drug Administration-approved anti-sclerostin antibody that has shown promising results in the treatment of osteoporosis. Research is being conducted on the effect of anti-sclerostin antibody (Scl-Ab) as a therapeutic option in the management of periodontitis, and up till now, the results are promising. A comprehensive review of the literature was done using the PubMed database and Google Scholar. Research articles published before April 2023 with the search terms “sclerostin,” “periodontitis,” and “anti-sclerostin antibody” (Scl-Ab) were included. Most of the studies point toward a definitive association between chronic periodontitis and the levels of sclerostin. Numerous investigations underscore the significance of evaluating sclerostin levels as a diagnostic marker for periodontitis, and the application of anti-sclerostin antibodies as a potential therapeutic option for managing periodontitis and peri-implant diseases. However, further researches are required to delve into the therapeutic effects and possible side effects of Scl-Ab. Sclerostin antibodies show promise as an anabolic drug that enhances bone mass and could potentially become a viable therapeutic alternative for addressing periodontal conditions in future.
{"title":"Anti-sclerostin antibody – A potential therapeutic target for periodontal bone regeneration","authors":"Shruthi Reghunath, Roshni Ramesh, Raseena Beevi Nafeesa, Divya Purushothaman Visalakshy, Binitta Paul Kannappillil, Ambili Gopalakrishnan","doi":"10.4103/jorr.jorr_68_23","DOIUrl":"https://doi.org/10.4103/jorr.jorr_68_23","url":null,"abstract":"Sclerostin is a glycoprotein predominantly released by specialized bone-forming cells (osteocytes). It serves as a principal inhibitor of osteogenesis and plays a key act in modulating the metabolism of alveolar bone. Sclerostin is shown to contribute to the occurrence of periodontitis by regulating the remodeling of the alveolar bone. A monoclonal antibody which antagonizes sclerostin has become extremely useful for osteoanabolic therapies. Romosozumab is an Food and Drug Administration-approved anti-sclerostin antibody that has shown promising results in the treatment of osteoporosis. Research is being conducted on the effect of anti-sclerostin antibody (Scl-Ab) as a therapeutic option in the management of periodontitis, and up till now, the results are promising. A comprehensive review of the literature was done using the PubMed database and Google Scholar. Research articles published before April 2023 with the search terms “sclerostin,” “periodontitis,” and “anti-sclerostin antibody” (Scl-Ab) were included. Most of the studies point toward a definitive association between chronic periodontitis and the levels of sclerostin. Numerous investigations underscore the significance of evaluating sclerostin levels as a diagnostic marker for periodontitis, and the application of anti-sclerostin antibodies as a potential therapeutic option for managing periodontitis and peri-implant diseases. However, further researches are required to delve into the therapeutic effects and possible side effects of Scl-Ab. Sclerostin antibodies show promise as an anabolic drug that enhances bone mass and could potentially become a viable therapeutic alternative for addressing periodontal conditions in future.","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"6 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141690592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This survey delved into the diverse practices regarding the placement and removal of temporary restorations in the field of endodontics. Employing a Google Forms questionnaire containing 16 inquiries, the study sought to capture varied trends prevalent among practitioners. The survey was conducted for 2 months, engaging 250 participants through social media platforms by sharing a generated link for the Google survey. The questionnaire covered a spectrum of aspects related to temporary restoration procedures, aiming to gather insights into the methodologies, techniques, and protocols adopted by practitioners during these processes. By employing an Internet-based survey tool, the researchers efficiently collated responses from a diverse pool of professionals. The study’s focus encompassed understanding the nuances in temporary restoration practices, emphasizing the significance of structured guidelines or protocols in ensuring efficient and standardized procedures. Through the collected responses, the survey aimed to identify prevalent trends, disparities, and potentially innovative approaches in the placement and removal of temporary restorations within the domain of endodontics. Ultimately, the survey results are anticipated to provide valuable insights into the varied methodologies employed in temporary restoration procedures, potentially paving the way for standardization or enhancement of protocols in this critical aspect of endodontic therapy.
这项调查深入探讨了牙髓病学领域有关临时修复体的放置和拆除的各种做法。该研究采用了包含 16 个问题的 Google Forms 问卷，试图捕捉从业人员中普遍存在的各种趋势。调查为期两个月，250 名参与者通过社交媒体平台分享谷歌调查的生成链接。 调查问卷涵盖了与临时修复程序相关的各个方面，旨在深入了解从业人员在这些过程中采用的方法、技术和规程。通过使用基于互联网的调查工具，研究人员有效地整理了来自不同专业人士的回复。 研究重点包括了解临时修复实践中的细微差别，强调结构化指南或规程对确保高效和标准化程序的重要意义。调查旨在通过收集到的答复，确定牙髓病学领域内临时修复体的放置和拆除方面的普遍趋势、差异和潜在的创新方法。 最终，预计调查结果将为临时修复程序中采用的各种方法提供有价值的见解，从而有可能为牙髓治疗中这一关键环节的标准化或改进规程铺平道路。
{"title":"Assessing the application and removal of temporary restorations in endodontic practice: A survey-based study","authors":"N. Ingle, Anant Kumar Heda, Manoj Likhitkar, Deepali Birla, Thanima Chandran, Pooja Warade","doi":"10.4103/jorr.jorr_5_24","DOIUrl":"https://doi.org/10.4103/jorr.jorr_5_24","url":null,"abstract":"\u0000 \u0000 This survey delved into the diverse practices regarding the placement and removal of temporary restorations in the field of endodontics. Employing a Google Forms questionnaire containing 16 inquiries, the study sought to capture varied trends prevalent among practitioners. The survey was conducted for 2 months, engaging 250 participants through social media platforms by sharing a generated link for the Google survey.\u0000 \u0000 \u0000 \u0000 The questionnaire covered a spectrum of aspects related to temporary restoration procedures, aiming to gather insights into the methodologies, techniques, and protocols adopted by practitioners during these processes. By employing an Internet-based survey tool, the researchers efficiently collated responses from a diverse pool of professionals.\u0000 \u0000 \u0000 \u0000 The study’s focus encompassed understanding the nuances in temporary restoration practices, emphasizing the significance of structured guidelines or protocols in ensuring efficient and standardized procedures. Through the collected responses, the survey aimed to identify prevalent trends, disparities, and potentially innovative approaches in the placement and removal of temporary restorations within the domain of endodontics.\u0000 \u0000 \u0000 \u0000 Ultimately, the survey results are anticipated to provide valuable insights into the varied methodologies employed in temporary restoration procedures, potentially paving the way for standardization or enhancement of protocols in this critical aspect of endodontic therapy.\u0000","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141710353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jishnu Pradeep, F. Peedikayil, Soni Kottayi, A. Aravind, Aswathi Sreedharan
Stainless steel crowns are considered to be a practicable alternative in the restoration of carious primary tooth. This study was done to assess Indian pediatric dentists’ knowledge, attitude, and practice of this technique and related factors with the use of the Hall technique (HT). A well-structured preused online questionnaire was sent to pedodontists practicing in India through various social media groups and emails. Descriptive statistics were used to characterize survey responses. A Chi-square test was employed to check the distribution of responders using the HT. Statistically P < 0.05 or less was considered statistically significant. A total of 210 pedodontists participated in this survey. 66.20% of the participants have <10 years’ experience; majority of the participants are in private clinical practice in urban areas. 97.14% of Indian pedodontists are aware of HT, and 22.54% regularly practice HT. 37% of the participants has apprehension of change in vertical dimension due to ooclusal changes and 35% of the participants fear of pulpal damage due to Hall technique. A significant number of pedodontists who have passed master of dental surgery (MDS) in pediatric and preventive dentistry <10 years ago (P = 0.034*), those from academic institutions (P = 0.048*), and those from urban areas (P = 0.045*) practice HT. A substantial proportion of the respondents were familiar with the HT, but considerably less number of participants use it regularly in clinical practice. There is a scope for increased practice of this technique so that the children in need of treatment of multisurface carious lesions can benefit.
{"title":"Hall technique in children: A cross-sectional survey among Indian pedodontists","authors":"Jishnu Pradeep, F. Peedikayil, Soni Kottayi, A. Aravind, Aswathi Sreedharan","doi":"10.4103/jorr.jorr_7_24","DOIUrl":"https://doi.org/10.4103/jorr.jorr_7_24","url":null,"abstract":"\u0000 \u0000 Stainless steel crowns are considered to be a practicable alternative in the restoration of carious primary tooth. This study was done to assess Indian pediatric dentists’ knowledge, attitude, and practice of this technique and related factors with the use of the Hall technique (HT).\u0000 \u0000 \u0000 \u0000 A well-structured preused online questionnaire was sent to pedodontists practicing in India through various social media groups and emails. Descriptive statistics were used to characterize survey responses. A Chi-square test was employed to check the distribution of responders using the HT. Statistically P < 0.05 or less was considered statistically significant.\u0000 \u0000 \u0000 \u0000 A total of 210 pedodontists participated in this survey. 66.20% of the participants have <10 years’ experience; majority of the participants are in private clinical practice in urban areas. 97.14% of Indian pedodontists are aware of HT, and 22.54% regularly practice HT. 37% of the participants has apprehension of change in vertical dimension due to ooclusal changes and 35% of the participants fear of pulpal damage due to Hall technique. A significant number of pedodontists who have passed master of dental surgery (MDS) in pediatric and preventive dentistry <10 years ago (P = 0.034*), those from academic institutions (P = 0.048*), and those from urban areas (P = 0.045*) practice HT.\u0000 \u0000 \u0000 \u0000 A substantial proportion of the respondents were familiar with the HT, but considerably less number of participants use it regularly in clinical practice. There is a scope for increased practice of this technique so that the children in need of treatment of multisurface carious lesions can benefit.\u0000","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"202 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141708361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Rajeev, Karishma M Desai, Ramyani Sinha, Pallavi Saxena, K. Saikumar
Most HNC cases and deaths are due to both individual predispositions linked to certain genetic characteristics, and lifestyle behaviors (tobacco and alcohol use) and secondary is an association with human papillomavirus (HPV). One of the important molecular event in carcinogenesis that could result in invasion and migration predisposing to malignant transformation is alteration in the cell adhesion such as p120 catenin. The loss of p120 catenin (p120) and/or its phosphorylation causes destabilization of E-cadherin; thus, it regulates cadherin stability and turnover which affects the cell adhesiveness and migratory capacity. Therefore, the present review will give the details of p120 is linked to the invasiveness and progression of various human epithelial many tumor types, including OSCCs.
{"title":"Expression of p120 – Catenin in oral squamous cell carcinoma and apparently normal mucosa adjacent to oral squamous cell carcinoma","authors":"A. Rajeev, Karishma M Desai, Ramyani Sinha, Pallavi Saxena, K. Saikumar","doi":"10.4103/jorr.jorr_4_23","DOIUrl":"https://doi.org/10.4103/jorr.jorr_4_23","url":null,"abstract":"Most HNC cases and deaths are due to both individual predispositions linked to certain genetic characteristics, and lifestyle behaviors (tobacco and alcohol use) and secondary is an association with human papillomavirus (HPV). One of the important molecular event in carcinogenesis that could result in invasion and migration predisposing to malignant transformation is alteration in the cell adhesion such as p120 catenin. The loss of p120 catenin (p120) and/or its phosphorylation causes destabilization of E-cadherin; thus, it regulates cadherin stability and turnover which affects the cell adhesiveness and migratory capacity. Therefore, the present review will give the details of p120 is linked to the invasiveness and progression of various human epithelial many tumor types, including OSCCs.","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"15 1","pages":"171 - 177"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48876373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VR. Sakthi Soundarya Lakshmi, S. Aparna, P. Madan Kumar
Generic medicine is a pharmaceutical drug which contains the same active ingredients as a branded drug in terms of strength, dosage, route of administration, quality, safety, performance characteristics, and therapeutic use. Generic medicine plays a major role in providing affordable medicines to patients. This systematic review was done to identify the knowledge regarding generic medicine prescription among dental and medical professionals worldwide. The search was performed in four databases PubMed, Turning Research Into Practice database (Trip database), Cochrane Library, and Google Scholar to identify the relevant articles with specific keywords and the time filter was February 2012 to February 2022. Finally we included 11 cross-sectional studies. However, generic prescribing is not very much adopted in India due to a lack of awareness about regulatory standards used in generic drug manufacturing. Based on this, the systematic review found that limited knowledge and negative perception among medical and dental professionals about generic medicine are clearly a major barrier to the implementation of generic medicine.
仿制药是指在强度、剂量、给药途径、质量、安全性、性能特点和治疗用途方面与品牌药物含有相同活性成分的药物。仿制药在为患者提供负担得起的药物方面发挥着重要作用。这项系统综述旨在确定世界各地牙科和医学专业人员对非专利药物处方的了解。在PubMed、Turning Research Into Practice数据库（Trip数据库）、Cochrane Library和Google Scholar四个数据库中进行搜索，以识别具有特定关键词的相关文章，时间过滤器为2012年2月至2022年2月。最后，我们纳入了11项横断面研究。然而，由于对仿制药生产中使用的监管标准缺乏认识，印度并没有太多采用仿制药处方。基于此，系统综述发现，医学和牙科专业人员对仿制药的知识有限和负面看法显然是实施仿制药的主要障碍。
{"title":"Knowledge, attitude, and perception regarding generic medicine prescription among dental and medical professionals – A systematic review","authors":"VR. Sakthi Soundarya Lakshmi, S. Aparna, P. Madan Kumar","doi":"10.4103/jorr.jorr_47_22","DOIUrl":"https://doi.org/10.4103/jorr.jorr_47_22","url":null,"abstract":"Generic medicine is a pharmaceutical drug which contains the same active ingredients as a branded drug in terms of strength, dosage, route of administration, quality, safety, performance characteristics, and therapeutic use. Generic medicine plays a major role in providing affordable medicines to patients. This systematic review was done to identify the knowledge regarding generic medicine prescription among dental and medical professionals worldwide. The search was performed in four databases PubMed, Turning Research Into Practice database (Trip database), Cochrane Library, and Google Scholar to identify the relevant articles with specific keywords and the time filter was February 2012 to February 2022. Finally we included 11 cross-sectional studies. However, generic prescribing is not very much adopted in India due to a lack of awareness about regulatory standards used in generic drug manufacturing. Based on this, the systematic review found that limited knowledge and negative perception among medical and dental professionals about generic medicine are clearly a major barrier to the implementation of generic medicine.","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"15 1","pages":"161 - 170"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49561138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IAfreen Fathima, S. Rohini, S. Aparna, PD Madan Kumar
Introduction: In the rural population of South India, tooth loss affects 48.7% of people. In addition, there are now more patients with more than five congenitally missing adult teeth. This may cause a person's quality of life to decline and cause them to experience both physical and psychological discomfort. Materials and Methods: The current cross-sectional descriptive study was conducted over a period of month using a questionnaire-based survey (February 2022). Using G-POWER software version 3.1, the minimum sample size was calculated as 100 people, considering a study with an 80% power and a = 0.5. Results: Around 59.6% have answered right when asked about the source of dental stem cells (DSCs). 13.5 percentage have no idea about sourcing of stem cells, 6.7% state dental pulp stem cell, a very small population state periodontal tissue to be the source, while a minor group state it to be from apical papilla, <1% have no idea. Conclusion: Data of this study indicate that although there is typically good awareness regarding DSCs origins, uses, and clinical research best practises, there is not a comprehensive comprehension of these topics. The respondents have shown a quite favorable attitude toward improving their understanding of DSCs.
{"title":"Knowledge, attitude, and awareness of tooth stem cell banking among dentists","authors":"IAfreen Fathima, S. Rohini, S. Aparna, PD Madan Kumar","doi":"10.4103/jorr.jorr_44_22","DOIUrl":"https://doi.org/10.4103/jorr.jorr_44_22","url":null,"abstract":"Introduction: In the rural population of South India, tooth loss affects 48.7% of people. In addition, there are now more patients with more than five congenitally missing adult teeth. This may cause a person's quality of life to decline and cause them to experience both physical and psychological discomfort. Materials and Methods: The current cross-sectional descriptive study was conducted over a period of month using a questionnaire-based survey (February 2022). Using G-POWER software version 3.1, the minimum sample size was calculated as 100 people, considering a study with an 80% power and a = 0.5. Results: Around 59.6% have answered right when asked about the source of dental stem cells (DSCs). 13.5 percentage have no idea about sourcing of stem cells, 6.7% state dental pulp stem cell, a very small population state periodontal tissue to be the source, while a minor group state it to be from apical papilla, <1% have no idea. Conclusion: Data of this study indicate that although there is typically good awareness regarding DSCs origins, uses, and clinical research best practises, there is not a comprehensive comprehension of these topics. The respondents have shown a quite favorable attitude toward improving their understanding of DSCs.","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"15 1","pages":"139 - 144"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42523713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacques Gérard Edouma Bohimbo, Karl Grégoire, S. Fokam, Haibolda Vounsoumna, C. Messanga
Context: Cellulitis of the floor of the mouth is dangerous condition because of their life-threatening potential due to their locations. Aims: The objective of this study was to evaluate and document the pattern of cellulitis of the floor of the mouth seen in a hospital of rural region of Cameroon. Settings and Design: This descriptive and prospective study was conducted in the Odontostomatology Unit of the Garoua Regional Hospital (Cameroon). Subjects and Methods: All patients presenting with cellulitis of the floor of the mouth between December 2020 and February 2021 were included in the study. The data concerning demography (age and sex), clinic (risk factors, symptoms, signs, etiology, and evolutionary stage), treatment (medical, surgical, and their evolution), and prognosis were analyzed using quantitative descriptive analysis. Results: Thirty-four patients representing 10.39% of the total consulted were enrolled. The male represented 55.88%. The mean age was 31.68 years. The etiology was odontogenic in 91.18% of cases. Swelling (100%), pain (100%), trismus (97.65%), dysphagia (88.23%), asthenia (76.47%), cervical spreading (58.82%), and poor oral hygiene (94.11%) were the main clinical signs. The cellulitis was suppurative in 76.47% of cases. All patients received probabilistic antibiotic therapy. Corticosteroids (61.76%), surgical (91.18%), and etiological treatment (82.35%) were associated. Complications occurred in 8.82% of cases. A favorable evolution was seen in 94.12% of cases. Death occurred in 5.88% of cases. Conclusions: Cellulitis of the floor of the mouth is still frequent in developing countries. Adequate management of these pathologies is the main condition to reduce their mortality rate.
{"title":"Management of cellulitis of the floor of the mouth in a Cameroonian secondary hospital","authors":"Jacques Gérard Edouma Bohimbo, Karl Grégoire, S. Fokam, Haibolda Vounsoumna, C. Messanga","doi":"10.4103/jorr.jorr_19_23","DOIUrl":"https://doi.org/10.4103/jorr.jorr_19_23","url":null,"abstract":"Context: Cellulitis of the floor of the mouth is dangerous condition because of their life-threatening potential due to their locations. Aims: The objective of this study was to evaluate and document the pattern of cellulitis of the floor of the mouth seen in a hospital of rural region of Cameroon. Settings and Design: This descriptive and prospective study was conducted in the Odontostomatology Unit of the Garoua Regional Hospital (Cameroon). Subjects and Methods: All patients presenting with cellulitis of the floor of the mouth between December 2020 and February 2021 were included in the study. The data concerning demography (age and sex), clinic (risk factors, symptoms, signs, etiology, and evolutionary stage), treatment (medical, surgical, and their evolution), and prognosis were analyzed using quantitative descriptive analysis. Results: Thirty-four patients representing 10.39% of the total consulted were enrolled. The male represented 55.88%. The mean age was 31.68 years. The etiology was odontogenic in 91.18% of cases. Swelling (100%), pain (100%), trismus (97.65%), dysphagia (88.23%), asthenia (76.47%), cervical spreading (58.82%), and poor oral hygiene (94.11%) were the main clinical signs. The cellulitis was suppurative in 76.47% of cases. All patients received probabilistic antibiotic therapy. Corticosteroids (61.76%), surgical (91.18%), and etiological treatment (82.35%) were associated. Complications occurred in 8.82% of cases. A favorable evolution was seen in 94.12% of cases. Death occurred in 5.88% of cases. Conclusions: Cellulitis of the floor of the mouth is still frequent in developing countries. Adequate management of these pathologies is the main condition to reduce their mortality rate.","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"15 1","pages":"93 - 97"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45106082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Bhuvaneswari, H. Prasad, M. Rajmohan, K. Srichinthu, V. Prema, L. Mahalakshmi
Background: Pulp as well as periodontium has an interrelationship in terms of development, structure, and function. The interrelationship of periodontitis and pulpal pathologies is contentious with some rivals and evidently incongruous lines of evidence being presented in the literary. Aims and Objectives: The aim and objective of our study was to analyze, “the pulpal variations in the tooth affected by moderate-to-severe grade of periodontitis histopathologically.” Materials and Methodology: Twenty single-rooted, nondecayed, mobile teeth which were clinically and radiographically diagnosed as periodontally affected were extracted. The diagnosed and collected teeth were instantly fixed in 10% neutral-buffered formalin for 48 h, after sectioning off the crown to allow the formalin to diffuse through root canals and fix the pulp tissue. The formalin-fixed sectioned roots were decalcified with formalin-ethylenediaminetetraacetic acid (Hillman and Lee solution). It took around 8–10 weeks for decalcification. Demineralized specimens were further subjected to processing and stained using hematoxylin and eosin for analysis. Results: The common histopathological findings were inflammation (80%), which was of chronic type in most specimens. Edema (80%) and moderate-to-severe fibrosis (100%) were also noticed in a majority of the specimens. Other findings noticed were dilated blood vessels (30%) and atrophied blood vessels (30%) with free pulp stones (50%). Necrosis (10%) and loss of odontoblastic integrity were the least common findings. Conclusion: Histopathological changes of varying degrees of degeneration were noted in the pulp due to periodontitis.
{"title":"Histopathological changes of the pulp in periodontally compromised teeth","authors":"M. Bhuvaneswari, H. Prasad, M. Rajmohan, K. Srichinthu, V. Prema, L. Mahalakshmi","doi":"10.4103/jorr.jorr_15_22","DOIUrl":"https://doi.org/10.4103/jorr.jorr_15_22","url":null,"abstract":"Background: Pulp as well as periodontium has an interrelationship in terms of development, structure, and function. The interrelationship of periodontitis and pulpal pathologies is contentious with some rivals and evidently incongruous lines of evidence being presented in the literary. Aims and Objectives: The aim and objective of our study was to analyze, “the pulpal variations in the tooth affected by moderate-to-severe grade of periodontitis histopathologically.” Materials and Methodology: Twenty single-rooted, nondecayed, mobile teeth which were clinically and radiographically diagnosed as periodontally affected were extracted. The diagnosed and collected teeth were instantly fixed in 10% neutral-buffered formalin for 48 h, after sectioning off the crown to allow the formalin to diffuse through root canals and fix the pulp tissue. The formalin-fixed sectioned roots were decalcified with formalin-ethylenediaminetetraacetic acid (Hillman and Lee solution). It took around 8–10 weeks for decalcification. Demineralized specimens were further subjected to processing and stained using hematoxylin and eosin for analysis. Results: The common histopathological findings were inflammation (80%), which was of chronic type in most specimens. Edema (80%) and moderate-to-severe fibrosis (100%) were also noticed in a majority of the specimens. Other findings noticed were dilated blood vessels (30%) and atrophied blood vessels (30%) with free pulp stones (50%). Necrosis (10%) and loss of odontoblastic integrity were the least common findings. Conclusion: Histopathological changes of varying degrees of degeneration were noted in the pulp due to periodontitis.","PeriodicalId":31361,"journal":{"name":"Journal of Oral Research and Review","volume":"15 1","pages":"98 - 102"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70813843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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