Background: The cardiovascular (CV) diseases, including left ventricular hypertrophy (LVH) are major causes of morbidity and mortality in T2DM. The LVH is associated with ventricular arrhythmias, ischemic heart disease (IHD), heart failure and sudden death. Although the LVH is frequent in T2DM, screening for this disorder is frequently done. Material and Methods: In this study, 120 Sudanese T2DM patients were recruited, (70 with and 50 without LVH) from four cardiac centers in Khartoum, the latter is inhabited by most of the Sudanese Afro-Arab ethnic groups. Clinical data were obtained from almost all patients together with measurement of glycemic and renal parameters. Echocardiography was performed for each patient, the left ventricle geometry components including the relative wall thickness (RWT) were estimated and the left ventricle mass index (LVMI) was calculated. Results: The commonest LVH type was eccentric (65.7%), and grade was severe (37.1%), and both were strongly associated, p<0.001, while the frequency of the mild LVH was 28.6%. Out of 10 tested variables only HhA1c (p<0.001), urea (p=0.039) and creatinine (p=0.043) were significantly associated with LVH, while the sex, age, T2DM duration, smoking, obesity, random and fasting blood glucose were not. Moreover, the LVMI was positively correlated with HbA1c (CC0.188, p<0.039), and negatively with RWT (CC-0.495, p<0.000). Finally, significantly higher number of patients with IHD (p=0.038) and cerebral complications (p=0.014) had LVH. Conclusion: In this unique setting of interethnic cross, the results suggest that more genetic than environmental factors could be involved in diabetic LVH development.
{"title":"Correlates and Severity of Left Ventricular Hypertrophy in Type 2 Diabetes Patients in an Afro-Arab-cross Ethnic Community","authors":"Hayder A Giha","doi":"10.31579/2692-9759/054","DOIUrl":"https://doi.org/10.31579/2692-9759/054","url":null,"abstract":"Background: The cardiovascular (CV) diseases, including left ventricular hypertrophy (LVH) are major causes of morbidity and mortality in T2DM. The LVH is associated with ventricular arrhythmias, ischemic heart disease (IHD), heart failure and sudden death. Although the LVH is frequent in T2DM, screening for this disorder is frequently done. Material and Methods: In this study, 120 Sudanese T2DM patients were recruited, (70 with and 50 without LVH) from four cardiac centers in Khartoum, the latter is inhabited by most of the Sudanese Afro-Arab ethnic groups. Clinical data were obtained from almost all patients together with measurement of glycemic and renal parameters. Echocardiography was performed for each patient, the left ventricle geometry components including the relative wall thickness (RWT) were estimated and the left ventricle mass index (LVMI) was calculated. Results: The commonest LVH type was eccentric (65.7%), and grade was severe (37.1%), and both were strongly associated, p<0.001, while the frequency of the mild LVH was 28.6%. Out of 10 tested variables only HhA1c (p<0.001), urea (p=0.039) and creatinine (p=0.043) were significantly associated with LVH, while the sex, age, T2DM duration, smoking, obesity, random and fasting blood glucose were not. Moreover, the LVMI was positively correlated with HbA1c (CC0.188, p<0.039), and negatively with RWT (CC-0.495, p<0.000). Finally, significantly higher number of patients with IHD (p=0.038) and cerebral complications (p=0.014) had LVH. Conclusion: In this unique setting of interethnic cross, the results suggest that more genetic than environmental factors could be involved in diabetic LVH development.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114714671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hypoplastic left heart syndrome is a congenital heart disease which accounts for 8% of all congenital heart defects. Twin pregnancies have a significantly higher risk of structural heart disease than singleton ones, however the concordance rate has been found to be relatively low, even in monochorionic pregnancies. We describe here the favorable evolution of a monochorionic, diamniotic, twin pregnancy in which both fetuses were diagnosed with hypoplastic left heart syndrome by antenatal echocardiography. The present report suggests that at least in some cases there may be a genetic contribution to the etiology. The fetal diagnosis was imperative to a good postnatal outcome.
{"title":"Successful Palliation in Monochorionic Twins with Hypoplastic Left Heart Syndrome","authors":"Tania Leme da Rocha Martinez","doi":"10.31579/2692-9759/047","DOIUrl":"https://doi.org/10.31579/2692-9759/047","url":null,"abstract":"Hypoplastic left heart syndrome is a congenital heart disease which accounts for 8% of all congenital heart defects. Twin pregnancies have a significantly higher risk of structural heart disease than singleton ones, however the concordance rate has been found to be relatively low, even in monochorionic pregnancies. We describe here the favorable evolution of a monochorionic, diamniotic, twin pregnancy in which both fetuses were diagnosed with hypoplastic left heart syndrome by antenatal echocardiography. The present report suggests that at least in some cases there may be a genetic contribution to the etiology. The fetal diagnosis was imperative to a good postnatal outcome.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123470263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiac pacing is the only treatment available for patients with Symptomatic bradyarrhythmias in the absence of reversible causes. For about 50 Apical right ventricular pacing has been used for years.
{"title":"Left Branch Cardiac Stimulation. Beginning of a Program in Icu","authors":"A. Carranza Pinel","doi":"10.31579/2692-9759/037","DOIUrl":"https://doi.org/10.31579/2692-9759/037","url":null,"abstract":"Cardiac pacing is the only treatment available for patients with Symptomatic bradyarrhythmias in the absence of reversible causes. For about 50 Apical right ventricular pacing has been used for years.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121787348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mostafa Q Al Shamiri, Waleed AlHarbi, Nouf Abdulaziz Alanazi, Ayman M. Alsaleh, Mobarak M, Alsaluli
Objective: The present study aims to estimate the prevalence of heart failure (HF) with preserved ejection fraction (HF-PEF) in patients with HF. The study also compares their clinical characteristics with heart failure and reduced ejection fraction among Saudi out patients. Methods: A Cross sectional, observational study was conducted by recruiting heart failure patients, who had an echocardiography within one year and the left ventricular ejection fraction >45%. The case report forms monitored for source documentation and accuracy. Results: The population sample included 26% women; with mean age 58 ±10 years (range 32 to 82). Of these patients, 66 did not have an EF measurement. Of the 330 patients with EF values, 168 had an EF of >45% and were classified as having HF-PEF and 162 had an EF < 45% and were classified as having HF-REF. Calcium channel blocker, thiazides diuretic and ARBs were more frequently used in HF-PEF. Conclusion: The study concluded that there is a need to develop safe and cost-effective methods for screening high-risk patients with multiple risk factors for the early detection and treatment of heart failure.
{"title":"Prevalence and Baseline Characteristics of Patients with Heart Failure and Preserved Ejection Fraction at Outpatients Sitting in Saudi Arabia","authors":"Mostafa Q Al Shamiri, Waleed AlHarbi, Nouf Abdulaziz Alanazi, Ayman M. Alsaleh, Mobarak M, Alsaluli","doi":"10.31579/2692-9759/048","DOIUrl":"https://doi.org/10.31579/2692-9759/048","url":null,"abstract":"Objective: The present study aims to estimate the prevalence of heart failure (HF) with preserved ejection fraction (HF-PEF) in patients with HF. The study also compares their clinical characteristics with heart failure and reduced ejection fraction among Saudi out patients. Methods: A Cross sectional, observational study was conducted by recruiting heart failure patients, who had an echocardiography within one year and the left ventricular ejection fraction >45%. The case report forms monitored for source documentation and accuracy. Results: The population sample included 26% women; with mean age 58 ±10 years (range 32 to 82). Of these patients, 66 did not have an EF measurement. Of the 330 patients with EF values, 168 had an EF of >45% and were classified as having HF-PEF and 162 had an EF < 45% and were classified as having HF-REF. Calcium channel blocker, thiazides diuretic and ARBs were more frequently used in HF-PEF. Conclusion: The study concluded that there is a need to develop safe and cost-effective methods for screening high-risk patients with multiple risk factors for the early detection and treatment of heart failure.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123459788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irion W. Pursell, Jessica W. Barnes, M. Massing, Sushma Dugyala, N. Cottoms
Serious health-related disparities continue to disproportionately impact underserved, low-wealth, and minority communities driven by an entanglement of factors. Studies show cardiovascular disease (CVD) prevalence in rural areas is advancing with widespread consequences on the local economies, health care systems, and population. Previous efforts in healthcare and community-based systems to impact rural CVD and CVD-related outcomes have been mostly unsuccessful for various reasons. The Lincoln Project (TLP) in Arkansas was conceived in response to this serious unmet need and with historical shortcomings in mind. TLP adopts a novel community health worker-led neighborhood-based strategy, bridging the gap between social resources, health care services and the rural communities they serve with the goal of rebalancing CVD-based health equity in areas of Arkansas with the most severe health disparities.
{"title":"The Arkansas Lincoln Project: Design of a Novel Interventional Model to Address Cardiovascular Health Disparities in Rural, Underserved Communities of the Arkansas Delta","authors":"Irion W. Pursell, Jessica W. Barnes, M. Massing, Sushma Dugyala, N. Cottoms","doi":"10.31579/2692-9759/049","DOIUrl":"https://doi.org/10.31579/2692-9759/049","url":null,"abstract":"Serious health-related disparities continue to disproportionately impact underserved, low-wealth, and minority communities driven by an entanglement of factors. Studies show cardiovascular disease (CVD) prevalence in rural areas is advancing with widespread consequences on the local economies, health care systems, and population. Previous efforts in healthcare and community-based systems to impact rural CVD and CVD-related outcomes have been mostly unsuccessful for various reasons. The Lincoln Project (TLP) in Arkansas was conceived in response to this serious unmet need and with historical shortcomings in mind. TLP adopts a novel community health worker-led neighborhood-based strategy, bridging the gap between social resources, health care services and the rural communities they serve with the goal of rebalancing CVD-based health equity in areas of Arkansas with the most severe health disparities.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117016821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hypertrophic cardiomyopathy (HCM) is a common hereditary cardiomyopathy that affects up to 1 in 200 people in the general population [1,2] Patients with HCM usually have asymmetric or isolated areas of left ventricular hypertrophy >15 mm that aren't caused by anything else. The majority of patients have left ventricular outflow tract (LVOT) blockage at rest or with provocation owing to systolic anterior motion (SAM) of the mitral valve with mitral-ventricular septal contact. In addition, SAM causes mild to moderate mitral regurgitation (MR), which is usually oriented posteriorly [3, 4]. Up to 60% of HCM patients experience cardiac issues after surgery (myocardial infarction (MI), congestive heart failure (CHF), or both) [5]. We will discuss anesthetic technique selection during noncardiac surgery for individuals with a preoperative diagnosis of HCM and provide some tips in this review.
{"title":"Tips in Anesthetic Techniques in Hypertrophic Cardiomyopathy","authors":"H. Degirmenci, H. Taş","doi":"10.31579/2692-9759/045","DOIUrl":"https://doi.org/10.31579/2692-9759/045","url":null,"abstract":"Hypertrophic cardiomyopathy (HCM) is a common hereditary cardiomyopathy that affects up to 1 in 200 people in the general population [1,2] Patients with HCM usually have asymmetric or isolated areas of left ventricular hypertrophy >15 mm that aren't caused by anything else. The majority of patients have left ventricular outflow tract (LVOT) blockage at rest or with provocation owing to systolic anterior motion (SAM) of the mitral valve with mitral-ventricular septal contact. In addition, SAM causes mild to moderate mitral regurgitation (MR), which is usually oriented posteriorly [3, 4]. Up to 60% of HCM patients experience cardiac issues after surgery (myocardial infarction (MI), congestive heart failure (CHF), or both) [5]. We will discuss anesthetic technique selection during noncardiac surgery for individuals with a preoperative diagnosis of HCM and provide some tips in this review.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125607106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rama Kumari N, Shahood Ajaz Kakroo, Archana Remala
Background: Contrast induced nephropathy (CIN) is a grave but underdiagnosed complication of percutaneous coronary intervention that is associated with increased in-hospital morbidity and mortality. Our aim was to study the incidence, risk factors of CIN and applicability of Mehran risk score (MRS) in Indian population. Methods: A total number of 432 patients were enrolled in the study. Patients of age ≥ 18 years with known CAD, ACS who underwent PCI were included. Patients were followed for development of CIN. Results: Mean eGFR of 88.4 + 30.65 ml/min/1.73 m2 and mean contrast volume usage of 122.8 + 41.9 ml. 64 patients (14.8%) developed CIN. On univariate analysis, age (p 0.435), gender (0.125), hypertension (0.679), diabetes (0.177), contrast volume (0.155) were not associated with development of CIN whereas, smoking (0.021), hypotension (<0.001), heart failure (<0.001), anemia (0.001) and median eGFR (p < 0.001) were significantly associated with development of CIN. The incidence of CIN was 2.7 fold higher (OR : 2.68, 95% CI : 1.299-5.540, p = 0.008) in the intermediate group (MRS 6-10), 5.4 fold higher (OR : 5.403, 95% CI : 2.249-12.978, p <0.001) in the high risk group (MRS 11-15) and 51 fold higher (OR : 51.059, 95% CI : 18.195-143.278, p <0.001) in the very high risk groups (MRS > 16) when compared to the low risk group (MRS < 5) respectively. Conclusions: The incidence of CIN in the very high risk group (MRS > 16) was substantially higher in our study (77.8 %) as compared to same group in Mehran study (57.3 %).
{"title":"Study of Risk Factors and Applicability of Mehran Risk Score in Predicting Contrast Induced Nephropathy in Patients Undergoing Percutaneous Coronary Intervention Patients – A Prospective Observational Cohort Study","authors":"Rama Kumari N, Shahood Ajaz Kakroo, Archana Remala","doi":"10.31579/2692-9759/035","DOIUrl":"https://doi.org/10.31579/2692-9759/035","url":null,"abstract":"Background: Contrast induced nephropathy (CIN) is a grave but underdiagnosed complication of percutaneous coronary intervention that is associated with increased in-hospital morbidity and mortality. Our aim was to study the incidence, risk factors of CIN and applicability of Mehran risk score (MRS) in Indian population. Methods: A total number of 432 patients were enrolled in the study. Patients of age ≥ 18 years with known CAD, ACS who underwent PCI were included. Patients were followed for development of CIN. Results: Mean eGFR of 88.4 + 30.65 ml/min/1.73 m2 and mean contrast volume usage of 122.8 + 41.9 ml. 64 patients (14.8%) developed CIN. On univariate analysis, age (p 0.435), gender (0.125), hypertension (0.679), diabetes (0.177), contrast volume (0.155) were not associated with development of CIN whereas, smoking (0.021), hypotension (<0.001), heart failure (<0.001), anemia (0.001) and median eGFR (p < 0.001) were significantly associated with development of CIN. The incidence of CIN was 2.7 fold higher (OR : 2.68, 95% CI : 1.299-5.540, p = 0.008) in the intermediate group (MRS 6-10), 5.4 fold higher (OR : 5.403, 95% CI : 2.249-12.978, p <0.001) in the high risk group (MRS 11-15) and 51 fold higher (OR : 51.059, 95% CI : 18.195-143.278, p <0.001) in the very high risk groups (MRS > 16) when compared to the low risk group (MRS < 5) respectively. Conclusions: The incidence of CIN in the very high risk group (MRS > 16) was substantially higher in our study (77.8 %) as compared to same group in Mehran study (57.3 %).","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124681107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The relationship between a person's lifestyle and the degree of atherosclerosis is very important. Trying to find such a connection is the goal of many researchers. It is also the purpose of the author's work, a brief description of which is given in this review. Method: Study of information on the Internet, participation in medical conferences, participation (only for 2021) in 3 international webinars on atherosclerosis, publication of articles. Results: The importance of this issue for modern man is very great.
{"title":"Atherosclerosis and Human Life Expectancy","authors":"V. Ermoshkin","doi":"10.31579/2692-9759/042","DOIUrl":"https://doi.org/10.31579/2692-9759/042","url":null,"abstract":"The relationship between a person's lifestyle and the degree of atherosclerosis is very important. Trying to find such a connection is the goal of many researchers. It is also the purpose of the author's work, a brief description of which is given in this review. Method: Study of information on the Internet, participation in medical conferences, participation (only for 2021) in 3 international webinars on atherosclerosis, publication of articles. Results: The importance of this issue for modern man is very great.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"12 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120928507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hayder A Giha, Osman Al-Sayed, Osman A. O. Alamin, Sara Osman AbdAllah Hassan
Background: Acute coronary syndrome (ACS), is ischemic heart disease of varying risk factors and clinical pattern and with immense health burden worldwide. Inflammation is believed to be an etiological factor in ACS, and neutrophil to lymphocyte ratio (NLR), to be a biomarker. Objectives: To describe the clinical pattern and risk factors of ACS in Afro-Arabs of Sudan and to evaluate the NLR as a severity marker. Method: In a total population, cross-sectional study, conducted in Al-Shaab Hospital- Sudan, clinical, laboratory and ECG data were used for ACS grouping into unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI) and STEMI. All patients underwent coronary angiography (CAG) and their Gensini score and NLR were calculated. Results: A total of 130 patients (62.3% men) of a median age of 58.0, 50.0-65.0 yrs., (range 32.0-82.0), were diagnosed with ACS; 44.6% STEMI, 37.7% NSTEMI and 17.7% UA. The median Gensini score was higher in STEMI (42.5, 12.0-71.0) and NSTEMI (40.0, 15.8-60.5) compared with UA (10.0, 5.0-23.0), p 0.002, similarly, was the NLR; 3.5, 1.6-4.6; 2.9, 1.5-3.8 and 0.9, 0.8-1.1, respectively p<0.001. Furthermore, the NLR in concordance with CAG findings p<0.001. Finally, hypertension, diabetes mellitus and dyslipidemia, respectively, were stronger ACS risk factors in women than in men unlike smoking, and family history imposed the least risk. Conclusion: While the ACS clinical pattern was in-line with literature, the risk factors order was different, and it was different between sexes. Importantly, the NLR strongly associated with ACS severity, but failed to distinguish between NSTEMI and STEMI.
{"title":"Disparity of risk factors and concordance of NLR with Gensini score in acute coronary syndrome in an Afro-Arab multiethnic nation","authors":"Hayder A Giha, Osman Al-Sayed, Osman A. O. Alamin, Sara Osman AbdAllah Hassan","doi":"10.31579/2692-9759/038","DOIUrl":"https://doi.org/10.31579/2692-9759/038","url":null,"abstract":"Background: Acute coronary syndrome (ACS), is ischemic heart disease of varying risk factors and clinical pattern and with immense health burden worldwide. Inflammation is believed to be an etiological factor in ACS, and neutrophil to lymphocyte ratio (NLR), to be a biomarker. Objectives: To describe the clinical pattern and risk factors of ACS in Afro-Arabs of Sudan and to evaluate the NLR as a severity marker. Method: In a total population, cross-sectional study, conducted in Al-Shaab Hospital- Sudan, clinical, laboratory and ECG data were used for ACS grouping into unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI) and STEMI. All patients underwent coronary angiography (CAG) and their Gensini score and NLR were calculated. Results: A total of 130 patients (62.3% men) of a median age of 58.0, 50.0-65.0 yrs., (range 32.0-82.0), were diagnosed with ACS; 44.6% STEMI, 37.7% NSTEMI and 17.7% UA. The median Gensini score was higher in STEMI (42.5, 12.0-71.0) and NSTEMI (40.0, 15.8-60.5) compared with UA (10.0, 5.0-23.0), p 0.002, similarly, was the NLR; 3.5, 1.6-4.6; 2.9, 1.5-3.8 and 0.9, 0.8-1.1, respectively p<0.001. Furthermore, the NLR in concordance with CAG findings p<0.001. Finally, hypertension, diabetes mellitus and dyslipidemia, respectively, were stronger ACS risk factors in women than in men unlike smoking, and family history imposed the least risk. Conclusion: While the ACS clinical pattern was in-line with literature, the risk factors order was different, and it was different between sexes. Importantly, the NLR strongly associated with ACS severity, but failed to distinguish between NSTEMI and STEMI.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131046546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Habib, M. Hillis, Aghayed Almobayed, Mohanned Alhadad, Khaled Hani Alkhodari
Arteriovenous malformations (AVM) of mandibula are rare abnormal congenital vascular condition that can result in serious complications. Although, various treatment options have been advocated in the literature, there seems to be no complete consensus on a suitable treatment option in these cases. Here, we describe a case of mandibular AVM, who has presented with massive oral bleeding, treated successfully by embolization of the bilateral external carotid arteries and the left superior thyroid artery. During the procedure, the patient developed symptoms of acute ischemic stroke that was diagnosed and managed during the same session by endovascular techniques.
{"title":"Mandibular AV Malformation: Life-Threatening Bleeding from the Mouth managed by Endovascular Intervention Complicated by Acute Ischemic Stroke on table. Case Report","authors":"M. Habib, M. Hillis, Aghayed Almobayed, Mohanned Alhadad, Khaled Hani Alkhodari","doi":"10.31579/2692-9759/041","DOIUrl":"https://doi.org/10.31579/2692-9759/041","url":null,"abstract":"Arteriovenous malformations (AVM) of mandibula are rare abnormal congenital vascular condition that can result in serious complications. Although, various treatment options have been advocated in the literature, there seems to be no complete consensus on a suitable treatment option in these cases. Here, we describe a case of mandibular AVM, who has presented with massive oral bleeding, treated successfully by embolization of the bilateral external carotid arteries and the left superior thyroid artery. During the procedure, the patient developed symptoms of acute ischemic stroke that was diagnosed and managed during the same session by endovascular techniques.","PeriodicalId":316029,"journal":{"name":"Cardiology Research and Reports","volume":"283 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123126928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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