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Odontogenic sinusitis: A state‐of‐the‐art review 牙源性鼻窦炎:最新进展综述
Q2 Medicine Pub Date : 2022-03-01 DOI: 10.1002/wjo2.9
J. Craig
Abstract Odontogenic sinusitis (ODS) is more common than historically reported, and is underrepresented in the sinusitis literature. ODS is distinct from rhinosinusitis in that it is infectious sinusitis from an infectious dental source or a complication from dental procedures, and most commonly presents unilaterally. ODS clinical features, microbiology, and diagnostic and treatment paradigms are also distinct from rhinosinusitis. ODS evaluation and management should generally be conducted by both otolaryngologists and dental providers, and clinicians must be able to suspect and confirm the condition. ODS suspicion is driven by certain clinical features like unilateral maxillary sinus opacification on computed tomography, overt maxillary dental pathology on computed tomography, unilateral middle meatal purulence on nasal endoscopy, foul smell, and odontogenic bacteria in sinus cultures. Otolaryngologists should confirm the sinusitis through nasal endoscopy by assessing for middle meatal purulence, edema, or polyps. Dental providers should confirm dental pathology through appropriate examinations and imaging. Once ODS is confirmed, a multidisciplinary shared decision‐making process should ensue to discuss risks and benefits of the timing and different types of dental and sinus surgical interventions. Oral antibiotics are generally ineffective at resolving ODS, especially when there is treatable dental pathology. When both the dental pathology and sinusitis are addressed, resolution can be expected in 90%–100% of cases. For treatable dental pathology, while primary dental treatment may resolve the sinusitis, a significant percentage of patients still require endoscopic sinus surgery. For patients with significant sinusitis symptom burdens, primary endoscopic sinus surgery is an option to resolve symptoms faster, followed by appropriate dental management. More well‐designed studies are necessary across all areas of ODS.
牙源性鼻窦炎(ODS)比以往报道的更为常见,在鼻窦炎文献中代表性不足。ODS不同于鼻鼻窦炎,因为它是感染性鼻窦炎,来自感染性牙齿源或牙科手术并发症,最常见的是单侧表现。ODS的临床特征、微生物学、诊断和治疗模式也不同于鼻窦炎。ODS的评估和管理通常应由耳鼻喉科医生和牙科医生共同进行,临床医生必须能够怀疑和确认这种情况。某些临床特征,如计算机断层扫描显示单侧上颌窦混浊,计算机断层扫描显示明显的上颌牙病变,鼻内窥镜检查显示单侧中牙脓毒,气味难闻,鼻窦培养中有牙源性细菌,这些都是引起ODS怀疑的原因。耳鼻喉科医生应通过鼻内窥镜检查鼻窦脓肿、水肿或息肉来确认鼻窦炎。牙科医生应通过适当的检查和成像来确认牙齿病理。一旦ODS被确认,多学科的共同决策过程应该随之而来,讨论时间和不同类型的牙科和鼻窦手术干预的风险和益处。口服抗生素通常对解决ODS无效,特别是当有可治疗的牙齿病理时。当口腔病理和鼻窦炎都得到解决时,可以预期90%-100%的病例得到解决。对于可治疗的牙齿病理,虽然初级牙科治疗可以解决鼻窦炎,但很大比例的患者仍然需要内窥镜鼻窦手术。对于有明显鼻窦炎症状负担的患者,初级内窥镜鼻窦手术是一种更快解决症状的选择,其次是适当的牙科治疗。需要在消耗臭氧层物质的所有领域进行更多精心设计的研究。
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引用次数: 7
Three‐hundred and sixty degrees of surgical approaches to the maxillary sinus 上颌窦360度手术入路
Q2 Medicine Pub Date : 2022-03-01 DOI: 10.1002/wjo2.12
N. Rezende, C. Pinheiro-Neto, Luciano C. P. C. Leonel, J. V. Van Gompel, M. Peris-Celda, Garret Choby
Abstract Objectives To demonstrate three‐hundred and sixty degrees of maxillary sinus (MS) surgical approaches using cadaveric dissections, highlighting the step‐by‐step anatomy of each procedure. Methods Two latex‐injected cadaveric specimens were utilized to perform surgical dissections to demonstrate different approaches to the MS. The procedures were documented with macroscopic images and endoscopic pictures. Results Dissections were performed to approach the MS medially (endoscopic maxillary antrostomy and ethmoidectomy), anteriorly (Caldwell–Luc), superiorly (transconjunctival/transorbital approach), inferiorly (transpalatal approach), and posterolaterally (preauricular hemicoronal approach). Conclusion A number of approaches have been described to address pathology in the MS. Surgeons should be familiar with indications, limitations, and surgical anatomy from different perspectives to approach the MS. This paper illustrates anatomic approaches to the MS with detailed step‐by‐step cadaveric dissections and case examples.
目的利用尸体解剖展示360度上颌窦(MS)手术入路,强调每个手术的一步一步解剖。方法采用两具注射乳胶的尸体标本进行手术解剖,以展示不同的ms入路,并通过宏观图像和内窥镜图像记录手术过程。结果采用内侧(内镜下上颌窦口造口和筛窦切除术)、前方(Caldwell-Luc)、上方(经结膜/经眶入路)、下方(经腭入路)和后外侧(耳前半冠状入路)进行解剖。结论:在多发性硬化症中,外科医生应该熟悉适应症、局限性和手术解剖学,从不同的角度来处理多发性硬化症。本文通过详细的一步一步的尸体解剖和案例说明了多发性硬化症的解剖方法。
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引用次数: 3
Exclusively endoscopic surgical resection of esthesioneuroblastoma: A systematic review 完全内窥镜手术切除感觉神经母细胞瘤:系统回顾
Q2 Medicine Pub Date : 2022-03-01 DOI: 10.1002/wjo2.10
Daniel B. Spielman, Andi Liebowitz, Maeher R Grewal, Chetan Safi, J. Overdevest, A. Iloreta, Brett E. Youngerman, D. Gudis
Abstract Background Historically sinonasal malignancies were always addressed via open craniofacial surgery for an oncologic resection. Increasingly esthesioneuroblastomas are excised using an exclusively endoscopic approach, however, the rarity of this disease limits the availability of long‐term and large scale outcomes data. Objective The primary objective is to evaluate the treatment modalities used and the overall survival of patients with esthesioneuroblastoma managed with exclusively endoscopic surgery. Methods In accordance with PRISMA guidelines, PubMed was queried to identify studies describing outcomes associated with endoscopic management of esthesioneuroblastomas. Results Forty‐four out of 2462 articles met inclusion criteria, totaling 399 patients with esthesioneuroblastoma treated with an exclusively endoscopic approach. Seventy‐two patients (18.0%) received adjuvant chemotherapy and 331 patients (83.0%) received postoperative radiation therapy. The average age was 50.6 years old (range 6–83). Of the 399 patients, 57 (16.6%) were Kadish stage A, 121 (35.2%) were Kadish stage B, 145 (42.2%) were Kadish stage C, and 21 (6.1%) were Kadish stage D. Pooled analysis demonstrated that 66.0% of patients had Hyams histologic Grade Ⅰ or Ⅱ, while 34.0% of patients had Grade Ⅲ or Ⅳ disease. Negative surgical margins were achieved in 86.9% of patients, and recurrence was identified in 10.3% of patients. Of those with 5‐year follow‐up, reported overall survival was 91.1%. Conclusion Exclusively endoscopic surgery for esthesioneuroblastoma is performed for a wide range of disease stages and grades, and the majority of these patients are also treated with adjuvant chemotherapy or radiation therapy. Reported overall recurrence rate is 10.3% and 5‐year survival is 91.1%.
历史上,鼻窦恶性肿瘤总是通过开放性颅面手术进行肿瘤切除。越来越多的神经母细胞瘤通过内窥镜手术切除,然而,这种疾病的罕见性限制了长期和大规模结果数据的可用性。主要目的是评估采用内窥镜手术治疗的感觉神经母细胞瘤患者的治疗方式和总生存率。方法根据PRISMA指南,检索PubMed,以确定描述内窥镜治疗感觉神经母细胞瘤相关结果的研究。2462篇文章中有44篇符合纳入标准,共399例采用内窥镜治疗的神经母细胞瘤患者。72例(18.0%)患者接受了辅助化疗,331例(83.0%)患者接受了术后放疗。平均年龄50.6岁(范围6-83岁)。在399例患者中,57例(16.6%)为卡迪什A期,121例(35.2%)为卡迪什B期,145例(42.2%)为卡迪什C期,21例(6.1%)为卡迪什d期。综合分析显示66.0%的患者为Hyams组织学分级Ⅰ或Ⅱ,34.0%的患者为Ⅲ或Ⅳ级。86.9%的患者手术切缘呈阴性,10.3%的患者复发。在随访5年的患者中,总生存率为91.1%。结论内镜下手术治疗感觉神经母细胞瘤适用于各种疾病分期和分级,大多数患者同时接受辅助化疗或放疗。报道的总复发率为10.3%,5年生存率为91.1%。
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引用次数: 3
The Draf III procedure: A review of indications and techniques 程序草案III:适应症和技术回顾
Q2 Medicine Pub Date : 2022-03-01 DOI: 10.1002/wjo2.6
M. Noller, Jakob L Fischer, D. Gudis, Charles A. Riley
Abstract The Draf Ⅲ procedure involves the creation of a common frontal sinus cavity. The most common indication for the Draf Ⅲ procedure is chronic rhinosinusitis of the frontal sinuses despite the failure of more conservative interventions such as bilateral Draf Ⅱa procedures. Primary Draf Ⅲ may be indicated in patients with a high risk of failures such as those with severe polyposis and those with a frontal sinus opening less than 4 mm on computed tomography imaging. Other indications for the Draf Ⅲ include access for tumor removal and repair of traumatic fractures of the frontal sinus. The “inside‐out” Draf Ⅲ procedure is the standard approach when the frontal recess anterior–posterior diameter is wide enough for instrument access, usually larger than 4–5 mm. The “outside‐in” Draf Ⅲ procedure can be done when the frontal recess is too narrow to safely accommodate instruments. Regular follow‐up with debridement should be done to prevent neo‐ostium stenosis.
草案Ⅲ程序涉及创建一个共同额窦腔。尽管更保守的干预措施如双侧draftⅡa手术失败,但draftⅢ手术最常见的适应症是额窦慢性鼻窦炎。Primary draftⅢ可能适用于失败风险高的患者,如严重息肉病患者和计算机断层成像上额窦开口小于4mm的患者。draftⅢ的其他适应症包括肿瘤切除和额窦创伤性骨折的修复。当额隐窝前后直径足够宽,通常大于4-5毫米时,“内-外”draftⅢ程序是标准入路。当额部隐窝太窄,无法安全地放置器械时,可采用“外-内”draftⅢ程序。应定期随访并清创,以防止新口狭窄。
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引用次数: 5
Frontal lobe position after single‐layer cadaveric dermal matrix repair of large anterior skull base defects 单层尸体真皮基质修复大前颅底缺损后额叶定位
Q2 Medicine Pub Date : 2022-03-01 DOI: 10.1002/wjo2.23
Corinna G Levine, Abdullah N Al-Rasheedi, Alejandro M A Mantero, M. Al-Bar, R. Casiano
Abstract Objective Endoscopic repair of large anterior skull base (ASB) defects has excellent results when using multilayered repairs with a nasoseptal flap. However, in extensive intranasal tumors, a nasoseptal flap may not always be available. One alternative option is a flexible single‐layer ASB repair. Initial studies indicate low cerebrospinal fluid leak rates with a single‐layer repair. However, the level of frontal lobe support, particularly the propensity for a significant inferior displacement of the frontal lobe, is not known. The goal of this study is to determine the frontal lobe position after single‐layer acellular dermal allograft repair in large ASB defects. Study Design Retrospective cohort study. Setting Tertiary care medical center. Subjects and Methods This cohort study compares the frontal lobe position in adults who underwent endoscopic endonasal ASB tumor resection and single‐layer cadaveric dermal matrix repair (ASB cohort) with control subjects without intracranial abnormalities (control cohort). The ASB cohort includes subjects with an ASB defect of ≥5 cm anterior/posterior and ≥1.5 cm wide and who had imaging at least 2 months after surgery. The frontal lobe position is measured on sagittal CT/MRI using a reference line from the base of the sella to the nasion. A value of zero indicates that the inferior‐most aspect of the frontal lobe is at the level of the nasion−sellar line. A positive value indicates that the frontal lobe is inferior to the nasion−sellar line. The ASB cohort frontal lobe position is compared with the control cohort using the Mann−Whitney U test. A priori we set an absolute difference of 5 mm as a clinically significant difference. Results The ASB cohort includes 47 subjects who are 57% male with an average age of 60 years (range: 31−89 years). The most common ASB pathology is esthesioneuroblastoma (n = 21) and 81% of the ASB cohort had postoperative radiation. The control cohort includes 20 subjects who are 60% male, with a mean age of 45 years (range: 19−74 years). The majority of controls underwent imaging for head trauma (n = 13). The ASB mean frontal lobe position is −0.2 mm superior to the nasion−sellar line (range: −9.2 to 10.4 mm), while the control's mean frontal lobe position is 1.1 mm inferior to the nasion−sellar line. This difference is not statistically significant (P = 0.13) and does not reach our a priori definition of clinical significance. The frontal lobe position of ASB subjects who had radiation is closer to the nasion−sellar line as compared with those who did not undergo radiation. Conclusions Single‐layer acellular dermal graft repair maintains frontal lobe support and position in large ASB defects.
摘要目的鼻中隔瓣多层修复大前颅底缺损具有良好的内镜修复效果。然而,在广泛的鼻内肿瘤中,鼻中隔瓣可能并不总是可用的。另一种选择是灵活的单层ASB修复。初步研究表明单层修复的脑脊液漏率低。然而,额叶的支持水平,特别是额叶明显下移位的倾向,尚不清楚。本研究的目的是确定单层脱细胞真皮同种异体移植修复大ASB缺损后额叶的位置。研究设计回顾性队列研究。设置三级医疗中心。受试者和方法本队列研究比较了接受鼻内窥镜ASB肿瘤切除术和单层尸体真皮基质修复(ASB队列)的成人额叶位置与无颅内异常的对照组(对照组)。ASB队列包括ASB前/后≥5cm、≥1.5 cm宽且术后至少2个月有影像学检查的患者。在矢状位CT/MRI上使用从鞍底到鼻的参考线测量额叶位置。值为0表示额叶的最下端位于颈鞍线的水平。阳性表示额叶低于鼻鞍线。采用Mann - Whitney U检验比较ASB组与对照组的额叶位置。先验地,我们设定5毫米的绝对差异为临床显著性差异。结果ASB队列包括47名受试者,男性占57%,平均年龄60岁(范围:31 ~ 89岁)。最常见的ASB病理为神经母细胞瘤(n = 21), 81%的ASB患者术后接受放疗。对照组包括20名受试者,其中60%为男性,平均年龄45岁(范围:19 - 74岁)。大多数对照组接受头部外伤影像学检查(n = 13)。ASB组平均额叶位置比鼻鞍线高- 0.2 mm(范围:- 9.2至10.4 mm),而对照组的平均额叶位置比鼻鞍线低1.1 mm。这种差异没有统计学意义(P = 0.13),也没有达到我们对临床意义的先验定义。与未接受放射治疗的ASB受试者相比,接受放射治疗的ASB受试者的额叶位置更接近鼻-鞍线。结论单层脱细胞真皮移植修复大面积ASB缺损可维持额叶的支撑和位置。
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引用次数: 0
Septoplasty alone is not suitable for most structural nasal obstructions 单纯鼻中隔成形术不适用于大多数结构性鼻塞
Q2 Medicine Pub Date : 2021-10-01 DOI: 10.1016/j.wjorl.2020.05.007
Jin-Feng Liu , Zhan-Feng Yan , Zhi-Jin Zhang , Ning-Yu Wang

Septoplasty is widely used in the treatment of structural nasal obstructions, and it also has a good effect and a high degree of postoperative satisfaction. However, there a large number of structures demonstrate abnormalities related to structural nasal obstruction, including the external nose, maxilla, nasal cavity and paranasal sinus. Nasal septum deviation is only one signs of structural nasal obstruction and does not represent all possible structural abnormalities of the nasal cavity and its surrounding structure. Septoplasty is only performed to correct deviations of the nasal septum, which in many cases is obviously insufficient in restoring the symmetry of the nasal structure. Therefore, septoplasty alone is not suitable for the treatment of most structural nasal obstructions. Nasal ventilation expansion surgery, which typically covers more abnormal structural correction procedures than septoplasty, should be used when describing the treatment of structural nasal obstruction.

鼻中隔成形术广泛应用于结构性鼻塞的治疗,效果良好,术后满意度高。然而,有大量的结构表现出与结构性鼻塞相关的异常,包括外鼻、上颌骨、鼻腔和鼻副窦。鼻中隔偏曲只是结构性鼻塞的一个征象,并不能代表鼻腔及其周围结构的所有可能的结构异常。鼻中隔成形术仅用于纠正鼻中隔的偏差,在许多情况下,这显然不足以恢复鼻结构的对称性。因此,单纯的鼻中隔成形术不适用于大多数结构性鼻塞的治疗。鼻通气扩张手术通常比鼻中隔成形术涵盖更多的异常结构矫正手术,在描述结构性鼻塞的治疗时应使用。
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引用次数: 4
Phonosurgery: A review of current methodologies 声外科学:当前方法的回顾
Q2 Medicine Pub Date : 2021-10-01 DOI: 10.1016/j.wjorl.2020.09.001
Christopher Ulmschneider, Jeffrey Baker, Ian Vize, Jack Jiang

Cold-steel has served as the gold standard modality of phonosurgery for most of its history. Surgical laser technology has revolutionized this field with its wide use of applications. Additional modalities have also been introduced such as coagulative lasers, photodynamic therapy, and cryotherapy. This review will compare the surgical modalities of cold steel, surgical lasers, phototherapy and cryotherapy. The mechanism of action, tissue effects and typical uses will be addressed for each modality.

冷钢在其大部分历史中一直是声外科的金标准模式。外科激光技术的广泛应用使这一领域发生了革命性的变化。其他治疗方式也被引入,如凝固激光、光动力疗法和冷冻疗法。本文将比较冷钢、激光手术、光疗和冷冻治疗的手术方式。作用机制,组织效应和典型用途将讨论每种方式。
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引用次数: 5
Guide for Authors 作者指南
Q2 Medicine Pub Date : 2021-10-01 DOI: 10.1016/S2095-8811(21)00070-6
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引用次数: 0
The distribution of parotid gland neoplasms in a veteran population 退伍军人中腮腺肿瘤的分布
Q2 Medicine Pub Date : 2021-10-01 DOI: 10.1016/j.wjorl.2020.05.009
Adnan S. Hussaini , Navin R. Prasad , Edina Paal , Eshetu A. Tefera , Sonya Malekzadeh , Jessica H. Maxwell

Objective

Salivary gland tumors account for 6%–8% of head and neck neoplasms with the parotid gland as the most common primary site. Pleomorphic adenomas (PA) are considered the most common benign parotid gland neoplasms, followed by Warthin tumors (WT). The goal of this study was to investigate the distribution of parotid gland neoplasms among a United States veteran population.

Design

Retrospective chart review.

Setting

Washington DC Veterans Affairs Medical Center.

Participants

Veterans who underwent fine needle aspiration (FNA) for a parotid gland mass from 2000 to 2018 were included. Medical records were reviewed for gender, age, tobacco use, surgery date, and pathology results.

Main outcome measures

Changes in the distribution of parotid neoplasms and tobacco use over an 18-year period.

Results

Of 141 patients with parotid gland masses, 86.5% (n = 122) were benign, 9.9% (n = 14) were malignant, and 3.5% (n = 5) were indeterminate. Of benign tumors, WT accounted for the majority at 51.6%, followed by PA at 40.2%. When stratified by decade (2000–2009 and 2010–2018), the proportion of WT compared to all other benign and malignant neoplasms increased from 31.6% to 53.6%, whereas the proportion of PA decreased from 36.8% to 33.3%. The rate of tobacco use was unchanged at approximately 32.0% among our cohort from 2000 to 2018.

Conclusion

Among our cohort of veteran patients, WT was the most common benign parotid tumor and has increased in incidence over the last two decades despite an unchanged smoking rate.

目的涎腺肿瘤占头颈部肿瘤的6% ~ 8%,以腮腺为最常见的原发部位。多形性腺瘤(PA)被认为是最常见的腮腺良性肿瘤,其次是沃辛瘤(WT)。本研究的目的是调查美国退伍军人人群中腮腺肿瘤的分布。设计回顾性图表评审。华盛顿退伍军人事务医疗中心。参与者包括2000年至2018年接受细针抽吸(FNA)治疗腮腺肿块的退伍军人。回顾医疗记录的性别、年龄、吸烟、手术日期和病理结果。主要观察指标:18年间腮腺肿瘤分布和烟草使用的变化。结果141例腮腺肿物中,86.5% (n = 122)为良性,9.9% (n = 14)为恶性,3.5% (n = 5)不确定。在良性肿瘤中,WT占51.6%,其次是PA,占40.2%。当按十年(2000-2009年和2010-2018年)分层时,WT与所有其他良恶性肿瘤的比例从31.6%增加到53.6%,而PA的比例从36.8%下降到33.3%。从2000年到2018年,我们的队列中烟草使用率保持不变,约为32.0%。结论:在我们的退伍军人患者队列中,WT是最常见的腮腺良性肿瘤,尽管吸烟率不变,但其发病率在过去20年中有所增加。
{"title":"The distribution of parotid gland neoplasms in a veteran population","authors":"Adnan S. Hussaini ,&nbsp;Navin R. Prasad ,&nbsp;Edina Paal ,&nbsp;Eshetu A. Tefera ,&nbsp;Sonya Malekzadeh ,&nbsp;Jessica H. Maxwell","doi":"10.1016/j.wjorl.2020.05.009","DOIUrl":"10.1016/j.wjorl.2020.05.009","url":null,"abstract":"<div><h3>Objective</h3><p>Salivary gland tumors account for 6%–8% of head and neck neoplasms with the parotid gland as the most common primary site. Pleomorphic adenomas (PA) are considered the most common benign parotid gland neoplasms, followed by Warthin tumors (WT). The goal of this study was to investigate the distribution of parotid gland neoplasms among a United States veteran population.</p></div><div><h3>Design</h3><p>Retrospective chart review.</p></div><div><h3>Setting</h3><p>Washington DC Veterans Affairs Medical Center.</p></div><div><h3>Participants</h3><p>Veterans who underwent fine needle aspiration (FNA) for a parotid gland mass from 2000 to 2018 were included. Medical records were reviewed for gender, age, tobacco use, surgery date, and pathology results.</p></div><div><h3>Main outcome measures</h3><p>Changes in the distribution of parotid neoplasms and tobacco use over an 18-year period.</p></div><div><h3>Results</h3><p>Of 141 patients with parotid gland masses, 86.5% (n = 122) were benign, 9.9% (n = 14) were malignant, and 3.5% (n = 5) were indeterminate. Of benign tumors, WT accounted for the majority at 51.6%, followed by PA at 40.2%. When stratified by decade (2000–2009 and 2010–2018), the proportion of WT compared to all other benign and malignant neoplasms increased from 31.6% to 53.6%, whereas the proportion of PA decreased from 36.8% to 33.3%. The rate of tobacco use was unchanged at approximately 32.0% among our cohort from 2000 to 2018.</p></div><div><h3>Conclusion</h3><p>Among our cohort of veteran patients, WT was the most common benign parotid tumor and has increased in incidence over the last two decades despite an unchanged smoking rate.</p></div>","PeriodicalId":32097,"journal":{"name":"World Journal of OtorhinolaryngologyHead and Neck Surgery","volume":"7 4","pages":"Pages 285-290"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.wjorl.2020.05.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39504034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Prevalence and associated risk factors of recurrent otitis media with effusion in children in Upper Egypt 上埃及儿童复发性中耳炎伴积液的患病率及相关危险因素
Q2 Medicine Pub Date : 2021-10-01 DOI: 10.1016/j.wjorl.2020.08.002
Khaled Saad , Abobakr Abdelmoghny , Yasser F. Abdel-Raheem , Eman Fathalla Gad , Amira Elhoufey

Objective

We conducted this study to determine the associations of possible risk factors and prevalence of recurrent otitis media with effusion (OME) in a cohort of children in Upper Egypt.

Methods

This was a cross-sectional study undertaken in two tertiary referral centers in Upper Egypt. Associations of possible risk factors with prevalence of recurrent OME were studied. Multi-factor logistic regression analysis was done to recognize the statistically significant risk factors associated with recurrent OME.

Results

We collected the data of 2003 pediatric patients, of which 1016 were males (50.7%). A total number of 310 children have OME, including 159 males (51.3%). The prevalence rate of OME in our cohort was 15.5%. Multi-factor logistic regression analysis of the risk factors related to recurrent OME showed it was strongly associated with adenoid hypertrophy (P < 0.0001), tonsil hypertrophy (P < 0.0001), sinusitis (P < 0.0001), posterior nostril polyps (P = 0.009), allergic rhinitis (P < 0.0001), recurrent URTIs (P = 0.029) and gastroesophageal reflux (P = 0.031).

Conclusions

Our study showed that recurrent OME in children in Upper Egypt is a common multifactorial problem, especially in young age. In our locality, allergic rhinitis, recurrent upper respiratory tract infections, gastroesophageal reflux, adenoid and tonsil hypertrophy were the most important associated factors related to the etiopathogenesis of OME.

目的:我们进行了这项研究,以确定上埃及一组儿童中复发性中耳炎伴积液(OME)的可能危险因素与患病率之间的关系。方法:这是一项横断面研究,在上埃及的两个三级转诊中心进行。研究了可能的危险因素与OME复发率的关系。进行多因素logistic回归分析,以识别与OME复发相关的具有统计学意义的危险因素。结果共收集小儿患儿2003例,其中男性1016例,占50.7%。共有310名儿童患有OME,其中男性159名(51.3%)。我们的队列中OME的患病率为15.5%。多因素logistic回归分析显示,复发性OME与腺样体肥大密切相关(P <0.0001),扁桃体肥大(P <0.0001),鼻窦炎(P <0.0001),后鼻孔息肉(P = 0.009),变应性鼻炎(P <0.0001)、复发性尿路感染(P = 0.029)和胃食管反流(P = 0.031)。结论我们的研究表明,上埃及地区儿童复发性OME是一种常见的多因素问题,尤其是在年轻时期。在我们地区,变应性鼻炎、反复上呼吸道感染、胃食管反流、腺样体和扁桃体肥大是OME发病最重要的相关因素。
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引用次数: 11
期刊
World Journal of OtorhinolaryngologyHead and Neck Surgery
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