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High Dose of Vitamin C in Septic and Critically Ill Patients with COVID-19: A Narrative Review 大剂量维生素 C 用于 COVID-19 败血症和重症患者:叙述性综述
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14845
Kiumarth Amini, A. Sahebnasagh, Ronak Amini, Solomon Habtemariam, F. Najmeddin, M. Mojtahedzadeh
Background: The coronavirus disease of 2019 (COVID-19) may be considered sepsis on the basis that all the pathological events and the subsequent organ-to-organ interaction in sepsis also occur in COVID-19. In this article, the authors first discussed the rationale for the use of vitamin C (Vit-C) in sepsis and septic patients. They also reviewed the role of a high dose of Vit-C in COVID-19, which included clinical trials designed for the management of this viral disease. Methods: The researchers explored databases of PubMed, Scopus, ISI Web of Science, and Google Scholar. Data were extracted to assess the effects of Vit-C in septic patients and also the efficacy of supplementation with a high dose of Vit-C regarding the clinical outcomes of patients with COVID-19. Results: Recent research findings indicate that severe inflammatory responses (cytokine storms) and oxidative stress are important causes for the high mortality in COVID-19 patients. It seems, however, that administering high doses of Vit-C can offer a therapeutic benefit. High doses of intravenous Vit-C, with its antioxidant properties and pleiotropic functions, could attenuate the tissue damage caused by excessive levels of free radicals following the cytokine storm and septic shock in severe cases of the disease. Conclusions: Recent literature suggests that high doses of Vit-C have a potential role in reducing mortality and intubation rates in critically ill COVID-19 patients. However, determining the optimal duration and dose of Vit-C in these patients requires further studies.
背景:2019 年冠状病毒病(COVID-19)可被视为败血症,其依据是败血症的所有病理事件和随后的器官间相互作用也发生在 COVID-19 中。在这篇文章中,作者首先讨论了在败血症和脓毒症患者中使用维生素 C(Vit-C)的理由。他们还回顾了大剂量维生素 C 在 COVID-19 中的作用,其中包括为治疗这种病毒性疾病而设计的临床试验。研究方法研究人员浏览了 PubMed、Scopus、ISI Web of Science 和 Google Scholar 等数据库。提取数据以评估 Vit-C 对败血症患者的影响,以及补充高剂量 Vit-C 对 COVID-19 患者临床疗效的影响。研究结果最新研究结果表明,严重的炎症反应(细胞因子风暴)和氧化应激是 COVID-19 患者死亡率高的重要原因。然而,注射大剂量的维生素 C 似乎能带来治疗效果。大剂量静脉注射的 Vit-C 具有抗氧化特性和多种功能,可减轻细胞因子风暴和严重脓毒性休克后自由基水平过高造成的组织损伤。结论最新文献表明,大剂量 Vit-C 有可能降低 COVID-19 重症患者的死亡率和插管率。然而,确定 Vit-C 在这些患者中的最佳持续时间和剂量还需要进一步研究。
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引用次数: 0
Nutrition in Disasters 灾难中的营养
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14835
A. Marzban, Fateme Sadeghi-Nodoushan
The Article Abstract is not available.  
文章摘要不详。
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引用次数: 0
The Study of Increasing Shelf-Life of Meat by Using Nanocellulose-Chitosan Composite Film Obtained from Agricultural By-Products 使用从农副产品中提取的纳米纤维素-壳聚糖复合膜提高肉类保质期的研究
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14837
Mahboubeh Mirhosseini, Azadeh Afra, F. B. Banadkooki, Fatemeh Banifatemeh
Background: This research was conducted to design a bionanocomposite film for meat packaging with regard to environmental aspects. Methods: Cellulose nanoparticles (CNPs) were used as nano-reinforcing factors were generated using non-edible agricultural by-products. The bionanocomposite film which was recently developed contains CNPs and chitosan (CS); then, the nanocomposites were explored via SEM, FTIR, agar disc diffusion tests and X-ray crystallography (XRD). Finally, the film was used to pack meat pieces. Results: Investigation of the morphological and physical reports of the solid films indicated that the CNPs are well scattered in bionanocomposite film. The addition of CNPs within a CS improved Young’s modulus by about 12135% and the tensile strength by 583%. In addition, XRD photographs indicated that CNP peak appeared after being added to CS context. Antimicrobial activity demonstrated that nanocomposites exerted restrictive effect on Escherichia coli, Pseudomonas aeruginosa, Listeria monocytogenes, and Staphylococcus aureus bacteria. Using CS-nanocellulose composite as a packing film on meat surface leads to decreasing bacteria growth compared to nylon packing materials at 4˚C after 8 days of storage. Conclusion: Findings indicated that the recently designed CNP-CS films are a better replacement for common food packaging substances.
研究背景本研究旨在设计一种用于肉类包装的仿生复合薄膜,并考虑其环保问题。方法:使用非食用农副产品生成纤维素纳米颗粒(CNPs)作为纳米增强因子。然后,通过扫描电镜、傅立叶变换红外光谱、琼脂盘扩散试验和 X 射线晶体学(XRD)对纳米复合材料进行了研究。最后,薄膜被用来包装肉块。结果对固体薄膜形态和物理报告的研究表明,CNPs 在仿生复合薄膜中分散良好。在 CS 中添加 CNPs 后,杨氏模量提高了约 12135%,拉伸强度提高了 583%。此外,XRD 照片显示,CNP 峰在加入 CS 后出现。抗菌活性表明,纳米复合材料对大肠杆菌、绿脓杆菌、单核细胞增生李斯特菌和金黄色葡萄球菌具有抑制作用。在肉类表面使用 CS 纳米纤维素复合材料作为包装膜,与尼龙包装材料相比,在 4˚C 温度下储存 8 天后,细菌的生长速度会有所下降。结论研究结果表明,最近设计的 CNP-CS 薄膜是普通食品包装材料的更好替代品。
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引用次数: 0
Pesticide Residue in Iranian Fruits and Vegetables: A Systematic Review 伊朗水果和蔬菜中的农药残留:系统综述
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14847
F. Toorang, Bahareh Sasanfar, Hamed Pouraram, Soheyl Eskandari
Background: There is a growing concern about the health-threatening effects of pesticide residues in fruits and vegetables worldwide. This study systematically reviewed the published data on pesticide residues in Iranian fruits and vegetables to clarify the gap in this issue. Method: The authors systematically searched PubMed, Google Scholar, Scopus, SID, and Iran Medex to find published studies on pesticide residues in Iranian foods without time and language restrictions. The title and abstract of all articles were evaluated after removing duplicate articles (2289 articles) by two independent reviewers. Finally, 25 articles were found that reported pesticide residues in fruits and vegetables. There was a great variation in measurement methods and pesticides reported across studies, which precluded meta-analysis. Therefore, a summary of the included studies was only reported. Results: Twenty-four studies reporting pesticide residues in Iranian fruits and vegetables were included. The percentage of Iranian fruits and vegetables contaminated with pesticides exceeding the maximum residue limit (MRL) was less than 10% in most studies. Contaminated samples were collected mainly from cultivated areas such as fields, orchards, or greenhouses. Conclusion: Pesticide residues in food have not been systematically reported in Iran. It was found that only limited articles were published by academic societies on this issue. Considering the current scenario, there is an urgent need to facilitate reliable and continuous measurements of toxic residues in Iranian food.
背景:全世界越来越关注水果和蔬菜中农药残留对健康的威胁。本研究系统地回顾了已发表的有关伊朗水果和蔬菜中农药残留的数据,以澄清在这一问题上的空白。研究方法作者对 PubMed、Google Scholar、Scopus、SID 和 Iran Medex 进行了系统检索,以查找有关伊朗食品中农药残留的已发表研究,不受时间和语言限制。在删除重复文章(2289 篇)后,由两名独立审稿人对所有文章的标题和摘要进行了评估。最后发现有 25 篇文章报告了水果和蔬菜中的农药残留。各研究报告的测量方法和农药残留量差异很大,因此无法进行荟萃分析。因此,本文仅对纳入的研究进行了总结。结果共纳入了 24 项报告伊朗水果和蔬菜中农药残留的研究。在大多数研究中,伊朗水果和蔬菜中农药残留量超过最高残留限量 (MRL) 的比例低于 10%。受污染的样本主要采集自田地、果园或温室等种植区。结论伊朗尚未系统报告食品中的农药残留。研究发现,学术团体就这一问题发表的文章非常有限。考虑到目前的情况,迫切需要对伊朗食品中的有毒残留物进行可靠和连续的测量。
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引用次数: 0
Urban Agriculture and Food Security: A Narrative Review 城市农业与粮食安全:叙述性评论
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14850
A. Marzban, Mohsen Dowlati, Fateme Sadeghi Nodoushan
Background Today, the world is facing the problems of population growth, urbanization, increasing need for food, depletion of water resources, and environmental degradation. Therefore, the present study investigates the impact of urban agriculture on food security. Methods: Search engines including PubMed, Scopus, Embase, Science Direct, Google scholar, Magiran, and scientific information database (SID) were applied with keywords such as population growth, food security, sustainable development, urban agriculture, food system to find related articles published up to 2022. Results: The impact of urban agriculture on food security can be seen through several factors such as nutritional stability, food availability, affordable food supply, and revenue generation through sales. Conclusion: Urban agriculture refers to production of food products in urban environment, where food is produced on rooftops, backyards, gardens, or in public open spaces. This work proposes new opportunities for sustainable development and urban management to make significant changes in living environment, health and land management. Furthermore, this research provides the poor in the city a chance to achieve food security by reducing household food costs.
背景 当今世界正面临着人口增长、城市化、粮食需求增加、水资源枯竭和环境退化等问题。因此,本研究调查了城市农业对粮食安全的影响。研究方法使用 PubMed、Scopus、Embase、Science Direct、Google scholar、Magiran 和科学信息数据库(SID)等搜索引擎,以人口增长、粮食安全、可持续发展、城市农业、粮食系统为关键词,查找截至 2022 年发表的相关文章。研究结果城市农业对粮食安全的影响体现在多个方面,如营养稳定性、食品供应、可负担得起的食品供应以及通过销售创收。结论都市农业是指在城市环境中生产食品,在屋顶、后院、花园或公共开放空间生产食品。这项工作为可持续发展和城市管理提供了新的机遇,使生活环境、健康和土地管理发生重大变化。此外,这项研究还为城市贫民提供了一个通过降低家庭食品成本实现食品安全的机会。
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引用次数: 0
The Association of Body Image Concern with Anthropometric Indices and Dietary Intakes in Adolescent Girls: A Cross-Sectional Study 青春期少女对身体形象的关注与人体测量指数和膳食摄入量的关系:一项横断面研究
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14836
A. Kohansal, Kimia Leilami, Mozhgan Hafizi, Alireza Rafiepour, M. Nouri, Zahra Sohrabi, Marzieh Akbarzade
Background: Due to the increasing prevalence of body image concern (BIC), especially in adolescent girls, and its potential associations with lifestyle factors and anthropometric indices, the present study was designed to evaluate the associations between BIC with anthropometric indices and dietary intake in adolescent girls. Methods: In this cross-section study, 210 adolescent girls aged 14-16 years were selected from high schools in Shiraz, Iran. Their anthropometric and demographic information were carefully recorded. Physical activity data were recorded through the International Physical Activity Questionnaire and information on dietary intake was collected using a 24-hour recall. To assess BIC, Littleton BIC questionnaire was applied. Regression analysis was used to assess the associations between variables. Results: Based on the results, 121 girls (55.8%) of the participants had no BIC, 70 (32.3%) had little, and 26 (12.0%) had medium BIC. Mean values of BMI, BMI for age centile, and z-scores were significantly different between BIC subgroups (P=0.008, 0.023, and 0.009, respectively). Mean values of height, and height for age centile, and z-scores were significantly different between BIC subgroups (P=0.018, 0.021, and 0.029, respectively). Risk of BIC increased, by 77% with 1 unit increase in z-score of height for age. Also, 1 kcal increase in daily energy intake led to 1% decrease in the risk of BIC. Conclusion: BIC was associated with lower calorie intake and higher z-score of height for age in adolescent girls.
背景:由于身体形象问题(BIC)的发生率越来越高,尤其是在青春期少女中,而且其与生活方式因素和人体测量指数之间存在潜在关联,本研究旨在评估青春期少女的身体形象问题与人体测量指数和饮食摄入量之间的关联。研究方法在这项横断面研究中,从伊朗设拉子市的高中选取了 210 名 14-16 岁的少女。仔细记录了她们的人体测量和人口统计学信息。体力活动数据通过国际体力活动调查表进行记录,饮食摄入量信息则通过 24 小时回忆法收集。为了评估 BIC,采用了利特尔顿 BIC 问卷。采用回归分析法评估变量之间的关联。结果结果显示,121 名女孩(55.8%)无 BIC,70 名女孩(32.3%)有少量 BIC,26 名女孩(12.0%)有中等 BIC。不同 BIC 亚组的体重指数(BMI)、BMI 年龄百分位数和 Z 值的平均值有显著差异(P 分别为 0.008、0.023 和 0.009)。身高平均值、年龄百分位数身高和 z 值在 BIC 亚组之间有显著差异(P 分别为 0.018、0.021 和 0.029)。年龄身高 z 值每增加一个单位,BIC 风险就会增加 77%。此外,每日能量摄入增加 1 千卡,BIC 风险降低 1%。结论青春期少女的 BIC 与较低的卡路里摄入量和较高的身高年龄 Z 值有关。
{"title":"The Association of Body Image Concern with Anthropometric Indices and Dietary Intakes in Adolescent Girls: A Cross-Sectional Study","authors":"A. Kohansal, Kimia Leilami, Mozhgan Hafizi, Alireza Rafiepour, M. Nouri, Zahra Sohrabi, Marzieh Akbarzade","doi":"10.18502/jnfs.v9i1.14836","DOIUrl":"https://doi.org/10.18502/jnfs.v9i1.14836","url":null,"abstract":"Background: Due to the increasing prevalence of body image concern (BIC), especially in adolescent girls, and its potential associations with lifestyle factors and anthropometric indices, the present study was designed to evaluate the associations between BIC with anthropometric indices and dietary intake in adolescent girls. Methods: In this cross-section study, 210 adolescent girls aged 14-16 years were selected from high schools in Shiraz, Iran. Their anthropometric and demographic information were carefully recorded. Physical activity data were recorded through the International Physical Activity Questionnaire and information on dietary intake was collected using a 24-hour recall. To assess BIC, Littleton BIC questionnaire was applied. Regression analysis was used to assess the associations between variables. Results: Based on the results, 121 girls (55.8%) of the participants had no BIC, 70 (32.3%) had little, and 26 (12.0%) had medium BIC. Mean values of BMI, BMI for age centile, and z-scores were significantly different between BIC subgroups (P=0.008, 0.023, and 0.009, respectively). Mean values of height, and height for age centile, and z-scores were significantly different between BIC subgroups (P=0.018, 0.021, and 0.029, respectively). Risk of BIC increased, by 77% with 1 unit increase in z-score of height for age. Also, 1 kcal increase in daily energy intake led to 1% decrease in the risk of BIC. Conclusion: BIC was associated with lower calorie intake and higher z-score of height for age in adolescent girls.","PeriodicalId":32114,"journal":{"name":"Journal of Nutrition and Food Security","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139807773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Consumption of Medicinal Plants among Patients with Diabetes in Eastern Mediterranean Regional Office Countries: A Systematic Review and Meta-Analysis 东地中海地区办事处国家糖尿病患者的药用消费:系统回顾与元分析
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14846
M. Ardakani, Nasim Namiranian, Mohammad Afkhami Ardekani, M. Zareipour, Ali Asadian, Sara Heydari
Background: Diabetes mellitus is a chronic disease which affects all aspects of human life. Medical herbs have become increasingly popular as complementary therapeutic measures for patients with diabetes. Thus, the present research aims to explore the consumption of medical herbs in patients with diabetes in Eastern Mediterranean Regional Office (EMRO) countries through a meta-analysis. Methods: The following keywords were searched: medicine, medicinal plants, healing plants, medicinal herbs, use, usage, frequency of use, prevalence, diabetes patients, type 2 diabetes, adults with diabetes, and EMRO countries. The databases searched included Scopus, PubMed, Web of Science, and Google Scholar. Results: A total of 3,542 papers were found. After omitting repeated or irrelevant papers, 70 papers were retained. An analysis of the abstract and full text of papers led to the retention of 35 papers. A great variance was found regarding the rate of consuming medical herbs in the papers (16.8-97.7%). The relative frequency of consuming medical herbs was 38% (95% CI: 33-44). Moreover, the most prevalent herbs were fenugreek (19%), cinnamon (18%), black seed (14%), white lupinus (13%), and olive (13%) with a 95% confidence interval. About 70% of patients (95%CI: 62-79) did not inform their physician of their herbal medicine consumption. Conclusion: In light of the present findings, it can be concluded that patients with diabetes use a wide range of medical herbs. Thus, health specialists and physicians need to be aware of the possible synergic or moderating effect of herbal medicine on the therapeutic measures taken for diabetes.
背景:糖尿病是一种影响人类生活各个方面的慢性疾病。作为糖尿病患者的辅助治疗措施,药草越来越受欢迎。因此,本研究旨在通过荟萃分析探讨东地中海地区办事处(EMRO)国家糖尿病患者的草药消费情况。方法:搜索以下关键词:医药、药用植物、治疗植物、药草、使用、用法、使用频率、患病率、糖尿病患者、2 型糖尿病、成人糖尿病患者、东地中海地区办事处国家。搜索的数据库包括 Scopus、PubMed、Web of Science 和 Google Scholar。结果:共找到 3,542 篇论文。在剔除重复或不相关的论文后,保留了 70 篇论文。对论文摘要和全文进行分析后,保留了 35 篇论文。论文中食用药草的比例差异很大(16.8%-97.7%)。服用药草的相对频率为 38%(95% CI:33-44)。此外,最常见的草药是葫芦巴(19%)、肉桂(18%)、黑种子(14%)、白羽扇豆(13%)和橄榄(13%),置信区间为 95%。约 70% 的患者(95% 置信区间:62-79)没有告知医生他们服用草药的情况。结论根据本研究结果,可以得出结论:糖尿病患者使用的草药种类繁多。因此,保健专家和医生需要了解草药对糖尿病治疗措施可能产生的协同或调节作用。
{"title":"Consumption of Medicinal Plants among Patients with Diabetes in Eastern Mediterranean Regional Office Countries: A Systematic Review and Meta-Analysis","authors":"M. Ardakani, Nasim Namiranian, Mohammad Afkhami Ardekani, M. Zareipour, Ali Asadian, Sara Heydari","doi":"10.18502/jnfs.v9i1.14846","DOIUrl":"https://doi.org/10.18502/jnfs.v9i1.14846","url":null,"abstract":"Background: Diabetes mellitus is a chronic disease which affects all aspects of human life. Medical herbs have become increasingly popular as complementary therapeutic measures for patients with diabetes. Thus, the present research aims to explore the consumption of medical herbs in patients with diabetes in Eastern Mediterranean Regional Office (EMRO) countries through a meta-analysis. Methods: The following keywords were searched: medicine, medicinal plants, healing plants, medicinal herbs, use, usage, frequency of use, prevalence, diabetes patients, type 2 diabetes, adults with diabetes, and EMRO countries. The databases searched included Scopus, PubMed, Web of Science, and Google Scholar. Results: A total of 3,542 papers were found. After omitting repeated or irrelevant papers, 70 papers were retained. An analysis of the abstract and full text of papers led to the retention of 35 papers. A great variance was found regarding the rate of consuming medical herbs in the papers (16.8-97.7%). The relative frequency of consuming medical herbs was 38% (95% CI: 33-44). Moreover, the most prevalent herbs were fenugreek (19%), cinnamon (18%), black seed (14%), white lupinus (13%), and olive (13%) with a 95% confidence interval. About 70% of patients (95%CI: 62-79) did not inform their physician of their herbal medicine consumption. Conclusion: In light of the present findings, it can be concluded that patients with diabetes use a wide range of medical herbs. Thus, health specialists and physicians need to be aware of the possible synergic or moderating effect of herbal medicine on the therapeutic measures taken for diabetes.","PeriodicalId":32114,"journal":{"name":"Journal of Nutrition and Food Security","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139808593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Crataegus Extract on the Relief of Heart Palpitation and Anxiety in Teenagers: An Interventional Quasi-Experimental Study 山楂提取物对缓解青少年心悸和焦虑的影响:一项干预性准实验研究
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14839
Mohammad Reza Alipour, Vakil Asadolahi, Mohammadtaghi Sarebanhassanabadi
Background: Heart palpitation is a common complaint defined as an unpleasant or abnormal heartbeat feeling. This study aimed to investigate the effectiveness of Crataegus extract on the relief of heart palpitations and anxiety in adolescents. Methods: This is an interventional quasi-experimental study performed from February 19, 2016 to February 19, 2017 on 120 adolescents aged 13 to 19 years with a complaint of heart palpitations, referring to heart clinic in Afshar Hospital of Yazd. The participants' demographic information, heartbeat feeling, Hamilton anxiety scaling, blood pressure, heartbeat rate, and electrocardiogram (ECG) were recorded. Patients were first treated with 20 drops every 8 hours for three days and then 25 drops every 8 hours for one month with Crataegus edible drops. They were then re-evaluated for heart palpations and anxiety. Results: Of 120 adolescents referring to Afshar Hospital with heart palpitations, 98 of participants (81.7%) experienced improvement. Mean differences in systolic blood pressure, heart rate, and anxiety scores before and after treatment with Crataegus extract decreased significantly by 1.71, 8.52, 6.55, respectively, but the mean difference in diastolic blood pressure increased by 1.46 (P<0.05). Conclusion: According to the results, Crataegus extract might be effective in reducing palpitation and anxiety in adolescents.  Further studies are suggested to approve the results of the study.
背景介绍心悸是一种常见的主诉,是指不愉快或不正常的心跳感觉。本研究旨在探讨山楂提取物对缓解青少年心悸和焦虑的效果。研究方法本研究是一项干预性准实验研究,研究时间为 2016 年 2 月 19 日至 2017 年 2 月 19 日,研究对象是亚兹德阿夫沙尔医院心脏门诊的 120 名以心悸为主诉的 13 至 19 岁青少年。参与者的人口统计学信息、心跳感觉、汉密尔顿焦虑评分、血压、心跳速率和心电图(ECG)均被记录在案。患者首先接受每 8 小时一次、每次 20 滴的治疗,为期三天,然后接受每 8 小时一次、每次 25 滴的山楂可食用滴剂治疗,为期一个月。然后重新评估他们的心脏触诊和焦虑情况。结果:在阿夫沙尔医院就诊的 120 名心悸青少年中,98 人(81.7%)的症状有所改善。山楂提取物治疗前后,收缩压、心率和焦虑评分的平均差异分别显著下降了1.71、8.52和6.55,但舒张压的平均差异增加了1.46(P<0.05)。结论根据研究结果,山楂提取物可有效减轻青少年的心悸和焦虑。 建议进一步研究以验证研究结果。
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引用次数: 0
A Review of the Effect of Synbiotic Foods on Reducing and Treating Constipation in Fasted People during the Month of Ramadan 综述复合益生菌食品对减轻和治疗斋月禁食者便秘的影响
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14848
M. Shirdeli, Fatemeh Yaghoubi, Fateme Sadeghi-Nodoushan, A. Marzban
Background: Fasting during Ramadan is an obligatory duty for all Muslims in the world. One of the most common side effects of fasting is constipation if fasted people do not follow a proper diet. Therefore, the purpose of this study is to review the effect of synbiotic foods on reducing and treating constipation in fasted people during Ramadan. Methods: Search engines including PubMed, Scopus, Embase, Science Direct, Google scholar, Magiran, and scientific information database (SID) were applied with keywords such as Fasting, Synbiotics, Constipation, Ramadan, Digestive System, Probiotics and Prebiotics to find related articles published up to 2022. Finally, 45 articles were included in the review. Results: Synbiotics are actually oral supplements and a mixture of probiotics and prebiotics. The use of these compounds, in addition to reducing the complication of constipation, has other benefits that can be a step towards reducing the use of drugs and changing lifestyle not only this month but also at other times. Conclusion: The use of fiber-containing compounds, beneficial for the activity of the gastrointestinal tract, both microbial and to improve its peristalsis, is especially necessary in the elderly, whose peristalsis has decreased due to aging. The placement of synbiotic foods such as synbiotic dairy products will help to control this complication due to the presence of prebiotics and beneficial probiotics.
背景介绍在斋月期间禁食是全世界所有穆斯林的义务。如果禁食者没有遵循适当的饮食习惯,禁食最常见的副作用之一就是便秘。因此,本研究旨在探讨合生元食品对减少和治疗斋月期间禁食者便秘的效果。研究方法使用PubMed、Scopus、Embase、Science Direct、Google scholar、Magiran和科学信息数据库(SID)等搜索引擎,以斋戒、合成益生菌、便秘、斋月、消化系统、益生菌和益生元为关键词,查找截至2022年发表的相关文章。最后,45 篇文章被纳入综述。研究结果合成益生菌实际上是一种口服补充剂,是益生菌和益生元的混合物。使用这些复合物,除了能减少便秘并发症外,还有其他好处,不仅能在本月,还能在其他时候减少药物使用,改变生活方式。结论使用含纤维的化合物对胃肠道的微生物活动和改善胃肠道的蠕动都有好处,对于因衰老而导致胃肠道蠕动减弱的老年人尤为必要。由于益生菌和有益益生菌的存在,添加益生菌食品(如益生菌乳制品)将有助于控制这种并发症。
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引用次数: 0
Interaction of Vitamin D Receptor Gene FokI Variants and Omega-3 Fatty Acids on Perceived Stress Score and Serum Cortisol Levels in Nurses: A Cross-Sectional Study 维生素 D 受体基因 FokI 变异与欧米茄-3 脂肪酸对护士感知压力评分和血清皮质醇水平的相互作用:一项横断面研究
Q4 Medicine Pub Date : 2024-02-03 DOI: 10.18502/jnfs.v9i1.14844
Zahra Veysi, Azadeh Dehghani, Mahnaz Sanjari, Z. Maghbooli, K. Mirzaei
Background: There is a high prevalence of perceived stress among nurses. Recent studies have shown that omega-3 fatty acids and genetic variants contribute to perceived stress. This study aimed to examine interactions between vitamin D receptor (VDR) gene FokI polymorphism and omega-3 fatty acids on perceived stress score and serum cortisol levels in nurses. Methods: A total of 268 Iranian nurses (248 women; 20 men) participated in this cross-sectional study. Omega-3 fatty acids and perceived stress score of participants were evaluated using a 3-day food record and the Perceived Stress Scale (PSS)-10, respectively. Serum cortisol concentrations were evaluated by ELISA. VDR FokI polymorphism was genotyped using the restriction fragment length polymorphism method. Results: No significant relationship was found between omega-3 fatty acids with perceived stress score or cortisol level in FF genotype carriers, but lower intake of PUFA was related to higher cortisol level (P=0.04) in Ff carriers. Significant interactions were observed between VDR FOKI polymorphism and intakes of eicosapentaenoic acid (EPA) (P Interaction=0.06), linoleic acid (P Interaction=0.06), and docosahexaenoic acid (DHA) (P Interaction=0.06) on serum cortisol, so that lower intake of EPA, linoleic acid, and DHA was associated with an increase in cortisol levels in individuals with ff genotype. Moreover, in carriers of ff genotype, lower intake of EPA was related to the elevated perceived stress score (P Interaction=0.06). Conclusion: FokI polymorphism interacts with omega-3 fatty acids (EPA, linoleic acid, and DHA) to increase cortisol level and with EPA to increase perceived stress score in nurses.
背景:护士的压力感知率很高。最近的研究表明,ω-3 脂肪酸和基因变异会导致感知压力。本研究旨在探讨维生素 D 受体(VDR)基因 FokI 多态性和欧米伽-3 脂肪酸对护士感知压力评分和血清皮质醇水平的相互作用。研究方法共有 268 名伊朗护士(248 名女性;20 名男性)参加了这项横断面研究。研究人员分别使用 3 天食物记录和感知压力量表 (PSS)-10 对参与者的欧米伽-3 脂肪酸和感知压力得分进行了评估。血清皮质醇浓度通过 ELISA 方法进行评估。采用限制性片段长度多态性方法对 VDR FokI 多态性进行基因分型。结果显示在FF基因型携带者中,ω-3脂肪酸与感知压力得分或皮质醇水平之间没有发现明显的关系,但在Ff基因型携带者中,较低的PUFA摄入量与较高的皮质醇水平有关(P=0.04)。VDR FOKI多态性与二十碳五烯酸(EPA)(P Interaction=0.06)、亚油酸(P Interaction=0.06)和二十二碳六烯酸(DHA)(P Interaction=0.06)的摄入量对血清皮质醇有显著的交互作用,因此在ff基因型携带者中,较低的EPA、亚油酸和DHA摄入量与皮质醇水平的升高有关。此外,在ff基因型携带者中,较低的EPA摄入量与较高的感知压力评分有关(P Interaction=0.06)。结论FokI 多态性与欧米伽-3 脂肪酸(EPA、亚油酸和 DHA)相互作用增加皮质醇水平,与 EPA 相互作用增加护士的压力感知得分。
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Journal of Nutrition and Food Security
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