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Preface to the second issue of Heart India 2023 《心脏印度2023》第二期前言
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_48_23
Ashutosh Kumar Singh
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引用次数: 0
Assessment of neurodevelopmental status using Development Assessment Scale for Indian Infants in children 6-24 months of age with congenital heart disease 用发育评估量表评估6-24月龄印度婴儿先天性心脏病患儿的神经发育状况
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_31_23
Jyotika Saini, M. Lazarus, Pradeep K. Jain, Pratibha Bamne
Subjects and Methods: The study included children 6–24 months of age with CHD confirmed by echocardiography. Their mental development quotient (DMeQ) and motor development quotient (DMoQ) was calculated using DASII. Developmental delay is defined as DQ <70% (<2 standard deviation) in either mental or motor domain. Statistical Analysis Used: Data entered in Excel spreadsheets and analyzed using SPSS 25.0. Results: Motor delay was found in 28% children and 26% children had mental delay (P = 0.0001). Among children with cyanotic CHD, both motor and mental development was seen in 80%, while in children with acyanotic CHD 18.8% children had motor delay and 16.5% children had mental delay (P = 0.0001). The mean DMoQ and mean DMeQ was significantly lower in the cyanotic group than in acyanotic group. The mean DMoQ and mean DMeQ was found to be significantly lower in the children with severe disease as compared to children with mild disease, as well as in the high-risk group as compared to low-risk group (P = 0.0001). Conclusions: We found high rates of motor and mental delay in children with cyanotic CHD, severe cardiac lesions, and high-risk category groups. Still, there is a need to find other associated factors, which can contribute to developmental delay, identified at the time of diagnosis through appropriate screening methods. Routine follow-up of these high-risk children with neurodevelopment assessment using DASII scale and early intervention will allow maximum growth and development of pediatric population with CHD and will have a positive impact on their quality of life. Context: With improved awareness, early screening and diagnosis, and better postoperative care, the survival rate and life expectancy of congenital heart disease (CHD) population is on rise, and hence there is the uttermost need to study morbidities like neurodevelopment delay, which significantly affect quality of life in long term. Aim: Assessment of Neurodevelopmental Status Using Development Assessment Scale for Indian Infants (DASII) in children 6-24 months of age with CHD. Settings and Design: This was a descriptive, cross-sectional, hospital-based study, conducted in a tertiary care hospital of Central India.
对象和方法:研究对象为经超声心动图证实的6-24月龄冠心病患儿。采用DASII计算其心理发展商(DMeQ)和运动发展商(DMoQ)。发育迟缓定义为智力或运动领域的DQ <70%(<2个标准差)。使用的统计分析:数据以Excel电子表格输入,使用SPSS 25.0进行分析。结果:28%的儿童存在运动迟缓,26%的儿童存在智力迟缓(P = 0.0001)。青紫型冠心病患儿中运动和智力发育均有80%,无青紫型冠心病患儿中运动迟缓和智力发育分别为18.8%和16.5% (P = 0.0001)。平均DMoQ和平均DMeQ均明显低于无氰组。重度疾病患儿的平均DMoQ和平均DMeQ显著低于轻度疾病患儿,高危组的平均DMoQ和平均DMeQ显著低于低危组(P = 0.0001)。结论:我们发现在患有紫绀型冠心病、严重心脏病变和高危人群的儿童中,运动和智力迟缓的发生率很高。尽管如此,仍有必要通过适当的筛查方法,在诊断时发现可能导致发育迟缓的其他相关因素。对这些高危儿童进行常规随访,采用DASII量表进行神经发育评估,并进行早期干预,可以最大限度地促进儿童冠心病人群的生长发育,并对其生活质量产生积极影响。背景:随着认识的提高、早期筛查和诊断以及术后护理的改善,先天性心脏病(CHD)人群的生存率和预期寿命不断上升,因此迫切需要对神经发育迟缓等显著影响长期生活质量的发病率进行研究。目的:应用印度婴儿发育评估量表(DASII)评价6-24月龄CHD患儿的神经发育状况。环境和设计:这是一项描述性、横断面、以医院为基础的研究,在印度中部的一家三级保健医院进行。
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引用次数: 0
Stent retrieval from renal artery by wire twist technique 应用钢丝扭转技术从肾动脉取出支架
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_28_23
Tanmay Mukhopadhyay, R. Roy
Wire twist technique is an important technique for retrieval of dislodged stent or broken coronary wire in areas where snare cannot be negotiated because of its bulky profile. In our patient dislodged coronary stent had been successfully retrieved from renal artery using twist wire technique. A 59 years gentleman, diabetic, hypertensive and smoker admitted with recent anterior wall myocardial infarction and ongoing chest pain. On coronary angiogram patient had approx. 80% stenosis in proximal LAD and approx. 80% stenosis in large OM1. PCI to LAD done with a 3X24 DES placed from ostium of LAD. But balloon dilation of OM lesion was difficult because of its tortuosity and also a 3X33 stent couldn't be negotiated . During removal of stent balloon came out and the stent was struck and hanging in the LCX to LM to Aorta. It spontaneously dislodged from coronary artery and entered right renal artery. However PCI to OM done with a smaller stent of 3X28 DES. A snare had been tried but couldn't be negotiated through the renal artery using right femoral route and JR(5F) guide cath. As an alternative approach three coronary wires had been passed through the side of the dislodged stent and multiple twisting done through a torquer. Thus the stent was entangled with the wires and the whole system was pulled and removed.
钢丝扭转技术是一种重要的技术,用于复位支架移位或冠状动脉钢丝断裂,而在这些区域,由于其庞大的外形,圈套无法通过。本病例采用扭转丝技术成功地从肾动脉中取出游离的冠状动脉支架。一个59岁的绅士,糖尿病,高血压和吸烟者承认最近的前壁心肌梗死和持续的胸痛。在冠状动脉造影中患者有大约。80%的LAD近端和近端狭窄。大网膜狭窄80%。PCI至LAD,从LAD口放置3X24 DES。但由于OM病变的弯曲性,球囊扩张困难,且无法协商3X33支架。在移除支架过程中,球囊出现,支架被击中并悬挂在LCX至LM至主动脉处。它自发地从冠状动脉脱落进入右肾动脉。然而,采用较小的3X28 DES支架进行PCI至OM。使用右股径和JR(5F)引导导管,尝试了圈套,但无法通过肾动脉。作为一种替代方法,三根冠状动脉导线穿过移位支架的一侧,并通过扭矩器进行多次扭转。因此,支架与金属丝纠缠在一起,整个系统被拉出并移除。
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引用次数: 0
A single-center retrospective study of Vitamin D status and acute left ventricular heart failure from a super specialty tertiary care hospital in Northeast India 印度东北部一家超级专科三级医院维生素D状态与急性左心室心力衰竭的单中心回顾性研究
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_23_23
A. Boro, P. Gupta, B. Paul, H. Rahman, S. Gang, Ananya Barman
Introduction: Heart failure (HF) is a progressive clinical condition and is a major cause of mortality and morbidity. Various studies have shown the association of Vitamin D deficiency with HF. The present study aimed to investigate the Vitamin D status among acute left ventricular failure (LVF) patients admitted to our hospital. Materials and Methods: Medical records of 55 acute LVF patients were retrospectively assessed. Patients were categorized according to their Vitamin D status. Demographics, risk factors, clinical presentations, and biochemical data of the patients were analyzed and documented. Results: Patients were grouped based on their Vitamin D status as deficient (40%; n = 22), insufficient (32.7%; n = 18), optimal (23.6%; n = 13), and toxic (3.6%; n = 2). The overall cohort included 67.3% (n = 37) of males with a male/female ratio of 2.1:1. Ages ranged from 22 to 86 years with a mean age of 64.8 years ± 2.3. Rural/Urban was 1:0.9. Hypertension (63.6%; n = 35) was the predominant risk factor across all groups. Mortality was the highest in the Vitamin D deficient group (36.4%; n = 8). The most common symptom observed was dyspnea (76.4%; n = 42). A high incidence of HF with reduced ejection fraction (58.1%; n = 32) was seen in the entire cohort with the highest prevalence in the Vitamin D-deficient group (27.3%; n = 15). Conclusions: Our study revealed a high occurrence of Vitamin D deficiency and insufficiency among HF patients. Routine screening of Vitamin D levels should be done in patients with unexplained cardiac problems. Serious adverse events, including HF, can be prevented and/or reduced on early diagnosis and treatment of Vitamin D deficiency/insufficiency.
引言:心力衰竭(HF)是一种进行性临床疾病,是导致死亡和发病的主要原因。各种研究表明维生素D缺乏与HF有关。本研究旨在调查我院收治的急性左心室衰竭(LVF)患者的维生素D状况。材料与方法:回顾性分析55例急性LVF患者的病历资料。根据患者的维生素D状况对其进行分类。对患者的人口学、危险因素、临床表现和生化数据进行了分析和记录。结果:根据患者的维生素D状况将其分为不足(40%;n=22)、不足(32.7%;n=18)、最佳(23.6%;n=13)和中毒(3.6%;n=2)。整个队列包括67.3%(n=37)的男性,男女比例为2.1:1。年龄22~86岁,平均年龄64.8±2.3岁。农村/城市为1:0.9。高血压(63.6%;n=35)是所有组的主要危险因素。维生素D缺乏组的死亡率最高(36.4%;n=8)。观察到的最常见症状是呼吸困难(76.4%;n=42)。在整个队列中,射血分数降低的HF发病率很高(58.1%;n=32),维生素D缺乏组的发病率最高(27.3%;n=15)。结论:我们的研究显示HF患者中维生素D缺乏和不足的发生率很高。对于有不明原因心脏问题的患者,应进行维生素D水平的常规筛查。维生素D缺乏/不足的早期诊断和治疗可以预防和/或减少包括HF在内的严重不良事件。
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引用次数: 0
Association of serum uric acid with left ventricular ejection fraction: A retrospective insight from a tertiary care hospital of North East India 血清尿酸与左心室射血分数的相关性:来自印度东北部一家三级护理医院的回顾性观察
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_25_23
P. Gupta, A. Boro, B. Paul, H. Rahman, Ananya Barman, P. Sarkar, S. Gang
Context: Cardiometabolic risk factors play crucial roles in left ventricular dysfunctions (left ventricular failure): a defining feature of heart failure (HF) with preserved ejection fractions (HFpEF). Among the many, serum uric acid (SUA) is a controversial risk factor that needs to be investigated globally. Aim: We aim to elucidate a correlation of SUA with ejection fraction percentage (EF%) in patients with chronic HF supporting the probable notion of hyperuricemia being a prognostic biomarker. Settings and Design: This retrospective, cohort study was performed on patients who visited from January 2022 to June 2022 in the Department of Cardiology at a tertiary care hospital in Northeastern India. Methods: A series of 81 selected patients with known congestive HF were documented with various baseline, clinical, and biochemical parameters. Patients were divided into three groups based on EF% and their relation with SUA, along with other parameters was analyzed. Statistical Analysis: Data were presented as mean ± standard deviation and frequencies for continuous variables and categorical variables, respectively. ANOVA one-way tests were conducted for continuous variables and Chi-square tests for categorical variables. P < 0.05 was considered as statistically significant. Results: A significant correlation was established between levels of SUA and EF (P = 0.021). Hence, hyperuricemia is directly related to an increased risk of lower EF. Conclusion: Even when asymptomatic, SUA can be used as a prognostic biomarker in the assessment of HF diseases.
背景:心脏代谢危险因素在左心室功能障碍(左心室衰竭)中起着至关重要的作用:左心室功能障碍是保留射血分数(HFpEF)的心力衰竭(HF)的决定性特征。其中,血清尿酸(SUA)是一个有争议的风险因素,需要在全球范围内进行调查。目的:我们的目的是阐明SUA与慢性心衰患者射血分数百分比(EF%)的相关性,支持高尿酸血症作为预后生物标志物的可能概念。背景和设计:这项回顾性队列研究是对2022年1月至2022年6月在印度东北部一家三级医院心内科就诊的患者进行的。方法:选择81例已知的充血性心力衰竭患者,记录各种基线、临床和生化参数。根据EF%及其与SUA的关系将患者分为三组,并分析其他参数。统计分析:连续变量以均数±标准差表示,分类变量以频率表示。对连续变量进行单因素方差分析,对分类变量进行卡方检验。P < 0.05为差异有统计学意义。结果:SUA与EF之间存在显著相关(P = 0.021)。因此,高尿酸血症与EF降低的风险增加直接相关。结论:即使无症状,SUA也可以作为评估HF疾病的预后生物标志物。
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引用次数: 0
Achromobacter: A bug in prosthetic heart valve 无色杆菌:人工心脏瓣膜中的一种细菌
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_32_23
J. Meher, S. Ashwanth
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引用次数: 0
Study of right ventricular outflow tract gradient in immediate postoperative period following intracardiac repair for tetralogy of Fallot 法洛四联症心内修复术后即刻右心室流出道梯度的研究
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_11_23
Vinay Upadhyay, P. Nayak, Ruchit Patel, Sandip Lukhi
Background: Surgical repair of tetralogy of Fallot (TOF) consists of adequate ventricular septal defect closure and relief of right ventricular outflow tract (RVOT) obstruction to the greatest extent possible. The residual RVOT gradient can be due to dynamic and fixed obstruction, and high gradient is sometimes seen even after a satisfactory RVOT resection often confirmed with intraoperative TransEsophageal Echocardiogram (TEE). Aim: The present study was conducted to study the changes in RVOT residual gradient in the early postoperative period. We analyzed the change in residual gradient by invasive monitoring intraoperatively after separating from cardiopulmonary bypass (CPB) in a case of intracardiac repair (ICR) for TOF and compared the readings 24 h after extubating the patients in intensive care unit (ICU). Materials and Methods: This was an observation study done in the Department of CTVS, Advanced Cardiac Centre, PGIMER, and Chandigarh from February 2018 to March 2019. A total of thirty patients with preoperative diagnosis of TOF were included in the study. After ICR for TOF, postseparation from CPB, RVOT gradient was measured using 23G needle connected to pressure transducer and compared with RVOT gradient measured 24 h postextubating using invasive line kept intraoperatively in pulmonary artery and RVOT. Results: There was a significant decrease in residual RVOT gradient postoperatively in ICU after 24 h of extubating, in comparison to intraoperative postbypass residual RVOT gradient. Postbypass residual RVOT gradient was 11.33 ± 1.39 that decreased to 7.81 ± 1.29 24 h after extubating (P < 0.05). Patients in whom pulmonary valve was preserved had greater postbypass residual RVOT gradient (12.44 ± 1.13) than patients with transannular patch (10.5 ± 0.90). However, both decreased after 24 h of extubating (9 ± 0.7 and 6.9 ± 0.8, respectively). Conclusion: Once satisfactory RVOT resection for fixed obstruction is done and is confirmed using TEE, the residual gradient, if marginally high, can be ignored as residual gradient significantly decreases after extubation and hemodynamic improvement is seen in postoperative period.
背景:法洛四联症(TOF)的外科修复包括充分闭合室间隔缺损和最大限度地缓解右心室流出道(RVOT)阻塞。残余的右心室流出道梯度可能是由于动态和固定的阻塞,即使在术中经食管超声心动图(TEE)证实了令人满意的左心室流出道切除后,有时也会出现高梯度。目的:研究RVOT残余梯度在术后早期的变化。我们分析了一例心内修复(ICR)TOF患者脱离体外循环(CPB)后术中有创监测残余梯度的变化,并比较了重症监护室(ICU)患者拔管后24小时的读数。材料和方法:这是一项2018年2月至2019年3月在CTVS部、高级心脏中心、PGIMER和昌迪加尔进行的观察研究。共有30名术前诊断为TOF的患者被纳入研究。TOF ICR后,CPB分离后,使用连接到压力传感器的23G针测量RVOT梯度,并与拔管后24小时使用术中保留在肺动脉和RVOT中的有创线测量的RVOT梯度进行比较。结果:与术中穿刺后残余RVOT梯度相比,拔管24小时后ICU的残余RVOT斜率显著降低。转流后残余RVOT梯度为11.33±1.39,拔管后24小时降至7.81±1.29(P<0.05)。保留肺动脉瓣的患者转流后剩余RVOT梯度(12.44±1.13)大于经环补片的患者(10.5±0.90)。然而,拔管24小时后两者均下降(分别为9±0.7和6.9±0.8)。结论:一旦对固定性梗阻进行了满意的RVOT切除并经食管超声心动图证实,残余梯度(如果略高)可以忽略,因为拔管后残余梯度显著降低,术后血流动力学改善。
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引用次数: 0
Clinical profile of patients having myocardial bridge on coronary angiography at tertiary care hospital in Rajasthan 拉贾斯坦邦三级医院冠状动脉造影心肌桥患者的临床概况
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_13_23
Archit Dahiya, M. Thakur, D. Agarwal, Gunjan Agarwal, H. Wardhan
Introduction: Myocardial bridge (MB) is usually defined as the segment of the coronary artery (epicardial) which passes intramurally. In the early days, it was not having any clinical importance, but later studies showed the presence of it in the left anterior descending (LAD) artery can be associated with myocardial infarction and cardiac death suddenly. Material and Methods: The aim of this study was mostly to assess the profile of patients with the MB on coronary angiography and to evaluate its association with atherosclerotic disease in the coronary artery at a tertiary care hospital in Rajasthan. In this study, evaluation was done (retrospectively) of the angiographic reports of the patients, and the prevalence of MB was seen totally, individually, or in combination with LAD, left circumflex, and right coronary artery. Results: Out of all 140 patients, 125 (89%) were males, and 15 (11%) were females. Among 140, the mean age of the patients having MB was 55.51 years. Out of 140 patients, 46% (65 patients) had diabetes, 41% (58 patients) had hypertension, and 42% (59 patients) were found to be smoker. Conclusion: The prevalence of MB in our study is similar to what is reported in the literature. The most common location of the MB was the mid-LAD segment.
心肌桥(MB)通常被定义为冠状动脉(心外膜)内部通过的一段。在早期,它没有任何临床意义,但后来的研究表明,它存在于左前降支(LAD)动脉可与心肌梗死和心源性猝死相关。材料和方法:本研究的主要目的是在拉贾斯坦邦的一家三级保健医院评估MB患者冠状动脉造影的概况,并评估其与冠状动脉粥样硬化疾病的关系。在本研究中,回顾性地评估了患者的血管造影报告,并观察了MB的患病率,包括整体、单独或与LAD、左旋冠状动脉和右冠状动脉合并。结果:140例患者中,男性125例(89%),女性15例(11%)。140例患者中,MB患者的平均年龄为55.51岁。在140名患者中,糖尿病患者占46%(65例),高血压患者占41%(58例),吸烟者占42%(59例)。结论:本研究中MB的患病率与文献报道相似。MB最常见的位置是lad中段。
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引用次数: 0
Successful implantation of dual-chamber permanent pacemaker in case of persistent left superior vena cava with the absence of right superior vena cava 双腔永久性起搏器成功植入左上腔静脉持续而右上腔静脉缺失的病例
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_20_23
Rajesh Sharma, S. Aggarwal
Persistent left superior vena cava (PLSVC), a rare congenital abnormality of the venous system, often goes unnoticed. Typically, it is identified incidentally while performing certain interventional procedures. It may manifest as sick sinus syndrome (SSS) or third-degree atrioventricular block, necessitating pacemaker implantation. This placement can be challenging since the dilated coronary sinus (CS) complicates locating the ventricular lead in certain circumstances. Here, the presented case focuses on a 55-year-old female presenting with SSS after complaining of presyncope, chest pain, and dizziness. The decision to implant a dual-chamber pacemaker was approved, but technical complications suggested a PLSVC with an absent right superior vena cava throughout the procedure. The particularity of this case was that, despite the anatomical difficulties, it was possible to cross the ventricular lead into the CS using a semicircular stylet.
持续性左上腔静脉(PLSVC)是一种罕见的先天性静脉系统异常,经常被忽视。通常,它是在执行某些介入程序时偶然发现的。它可能表现为病态窦房结综合征(SSS)或三度房室传导阻滞,需要植入起搏器。这种放置可能具有挑战性,因为在某些情况下,扩张的冠状窦(CS)使心室导线的定位变得复杂。在这里,本文的病例集中在一名55岁的女性身上,她在抱怨发作前、胸痛和头晕后出现SSS。植入双腔起搏器的决定获得批准,但技术并发症表明,在整个手术过程中,PLSVC存在右上腔静脉缺失。该病例的特殊性在于,尽管存在解剖困难,但使用半圆形探针将心室导线穿过CS是可能的。
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引用次数: 0
Correlation of diabetes complications with blood pressure variability 糖尿病并发症与血压变异性的相关性
Q4 Medicine Pub Date : 2023-05-01 DOI: 10.4103/heartindia.heartindia_19_23
S. Shakya, P. Verma, R. Karoli, P. Meena
Introduction: India is suffering from an epidemic of noncommunicable diseases. Type 2 diabetes and hypertension are two lifestyle diseases which are often coexistent. The present study aimed to assess whether blood pressure (BP) variability has any correlation with the prevalence of chronic complications of diabetes. Materials and Methods: In a hospital-based cross-sectional study, 116 patients of newly diagnosed type 2 diabetes were enrolled. Ambulatory BP monitoring (ABPM) for 24 h duration was performed in all the study participants. The abnormal patterns of BP were analyzed. Results: Out of 100 patients with valid ABPM data, 62% of patients had masked hypertension, 45% had nondipping pattern, and 13% had reverse dipping pattern. The prevalence of diabetes complications both macrovascular and microvascular was significantly higher in patients who had abnormal dipping patterns. Conclusion: Our findings highlight the importance of ABPM which detects masked hypertension, white-coat hypertension, and abnormal BP patterns which are related to complications of diabetes.
引言:印度正遭受非传染性疾病的流行。2型糖尿病和高血压是两种经常并存的生活方式疾病。本研究旨在评估血压(BP)变异性是否与糖尿病慢性并发症的患病率有任何相关性。材料和方法:在一项基于医院的横断面研究中,116名新诊断的2型糖尿病患者被纳入研究。对所有研究参与者进行24小时的动态血压监测(ABPM)。对血压异常模式进行分析。结果:在有有效ABPM数据的100名患者中,62%的患者有隐性高血压,45%的患者有非下倾模式,13%的患者有反向下倾模式。在有异常倾斜模式的患者中,糖尿病大血管和微血管并发症的发生率显著较高。结论:我们的研究结果强调了ABPM的重要性,它可以检测与糖尿病并发症相关的隐性高血压、白质高血压和异常血压模式。
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引用次数: 0
期刊
Heart India
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