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Role of optical coherence tomography in a case of coronary perforation 光学相干断层扫描在一例冠状动脉穿孔中的作用
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_9_20
P. S. Chowdary, V. Subrahmanya Sarma, Raghuram Palaparthi, G. Somasekhar, K. Gopalakrishna, K. Rao, M. Boochibabu, M. Prasad, Y. Sasidhar
Coronary angiography is the gold standard imaging modality during coronary interventions, but coronary angiogram has many limitations, catheter-based imaging modalities such as optical coherence tomography (OCT) have the potential to overcome these limitations, it plays a role in planning the procedure before stent implantation, it helps in optimizing the stent postprocedure and detecting mallapposition, edge dissection, but its role in coronary perforation has not been established in the literature, this is the first case reporting the OCT findings in a case of coronary perforation. This case highlights the fact that contained perforation can be diagnosed with the help of OCT, complimenting the coronary angiogram.
冠状动脉造影是冠状动脉介入治疗期间的金标准成像模式,但冠状动脉造影有许多局限性,基于导管的成像模式,如光学相干断层扫描(OCT)有可能克服这些局限性,它在支架植入前的程序规划中发挥作用,它有助于优化支架术后处理,检测错位、边缘夹层,但其在冠状动脉穿孔中的作用尚未在文献中得到证实,这是第一例报告冠状动脉穿孔OCT结果的病例。该病例强调了一个事实,即在OCT的帮助下,可以诊断出包含性穿孔,并补充冠状动脉造影。
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引用次数: 0
Transcatheter pulmonary valvuloplasty with coronary balloon for critical pulmonary atresia with intact ventricular septum in a neonate 经导管冠状动脉球囊肺动脉瓣成形术治疗新生儿完全性室间隔肺闭锁1例
Q4 Medicine Pub Date : 2020-07-01 DOI: 10.4103/heartindia.heartindia_1_20
V. Desabandhu, S. Narayanan, Mohanan S Sajeer
Pulmonary atresia with intact ventricular septum is a rare cause of cyanosis in a newborn. The prognosis and treatment of the condition depend on the pulmonary anatomy as well as the state of the right ventricle. We present a case where the patient presented with acute desaturation, and we had to do an emergency pulmonary valvotomy, using coronary wires and balloons, as a lifesaving procedure. The saturation improved on the table, and the patient could be discharged from hospital in a stable state. This particular case shows that opening an atretic pulmonary valve is a viable option and coronary wires and balloons can be used for the purpose.
肺闭锁与完整的室间隔是一个罕见的原因,在新生儿紫绀。病情的预后和治疗取决于肺解剖和右心室的状态。我们提出一个病例,病人表现出急性去饱和,我们不得不做一个紧急肺动脉瓣切开术,使用冠状动脉电线和气球,作为一个挽救生命的过程。手术台上饱和度提高,患者可以稳定出院。这个特殊的病例表明,打开肺动脉瓣是一个可行的选择,冠状动脉钢丝和球囊可用于此目的。
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引用次数: 0
A study on coronary artery anomalies in adult patients undergoing coronary angiography for various indications 不同适应症成人冠状动脉造影患者冠状动脉异常的研究
Q4 Medicine Pub Date : 2020-04-01 DOI: 10.4103/heartindia.heartindia_20_20
A. Moulick, B. Majhi, Gouranga Sarkar
Introduction: As variations in coronary artery anatomy is very common, the term “coronary artery anomaly” (CAA) applies only to the rarer forms of anatomic aberrations seen in the general population. CAAs are usually detected incidentally during coronary angiography (CAG) or autopsy. Some hemodynamically significant anomalies cause symptoms at young age and can cause sudden death. Knowledge of CAA is necessary to suspect them in appropriate clinical setting for early diagnosis and management that may be lifesaving. Subjects and Methods: Over a period of 1 year, we studied coronary anatomy of 1000 adult patients attending a tertiary cardiac center for coronary artery disease, valvular heart disease planning valve surgery, etc., where CAG was required. The absolute prevalence of different CAAs was recorded. Results: In our study, 3.6% of the patients had CAA. Most common of them were “right coronary artery arising from the left sinus” and “separate origin of the left anterior descending artery and left circumflex artery from the left sinus.” A significant coronary artery fistula was the next common. Conclusion: Some CAAs made coronary intervention technically challenging. There were hemodynamic implications in some, namely myocardial ischemia resulting from significant myocardial bridge and “coronary steal phenomenon” related to large coronary artery fistula. A high index of suspicion is required for early diagnosis, and the management of most serious forms can abort serious consequences. Information regarding CAAs is also helpful to overcome procedural difficulty during coronary and cardiothoracic interventions and avoid complications.
引言:由于冠状动脉解剖结构的变异非常常见,“冠状动脉异常”(CAA)一词仅适用于普通人群中罕见的解剖异常。CAA通常是在冠状动脉造影(CAG)或尸检时偶然发现的。一些血液动力学显著异常会在年轻时引起症状,并可能导致猝死。CAA的知识对于在适当的临床环境中怀疑它们是必要的,以便进行早期诊断和管理,这可能是救命的。受试者和方法:在一年的时间里,我们研究了1000名成年患者的冠状动脉解剖,这些患者在三级心脏中心接受冠状动脉疾病治疗,心脏瓣膜疾病计划瓣膜手术等,其中需要CAG。记录了不同CAA的绝对患病率。结果:在我们的研究中,3.6%的患者患有CAA。最常见的是“右冠状动脉起源于左窦”和“左前降支和左回旋支起源于左鼻窦”。其次是严重的冠状动脉瘘。结论:一些CAA使冠状动脉介入治疗在技术上具有挑战性。一些患者存在血液动力学影响,即由显著的心肌桥引起的心肌缺血和与大的冠状动脉瘘有关的“冠状动脉偷血现象”。早期诊断需要高的怀疑指数,而对最严重形式的治疗可能会导致严重后果。有关CAA的信息也有助于克服冠状动脉和心胸介入治疗过程中的程序困难,避免并发症。
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引用次数: 0
Preface to the second issue of Heart India 2020 《心印度2020》第二期序言
Q4 Medicine Pub Date : 2020-04-01 DOI: 10.4103/heartindia.heartindia_27_20
Ashutosh Kumar Singh
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引用次数: 0
Gender-based differences in coronary artery disease: A prospective observational study from a North Indian state 冠状动脉疾病的性别差异:来自印度北部一个州的前瞻性观察研究
Q4 Medicine Pub Date : 2020-04-01 DOI: 10.4103/heartindia.heartindia_13_20
Amit Sharma, M. Dar, M. Iqbal, N. Tramboo
Introduction: Coronary artery disease (CAD) causes significant morbidity and mortality in both genders, however, the importance of CAD in females is underappreciated. Aims and Objectives: This study is aimed at investigating the gender-based differences in presentation, evaluation, and outcome of CADs in a northern state of India. Materials and Methods: This is a prospective study conducted over a period of 3 years. All the patients with CAD (acute coronary syndrome or chronic stable angina) enrolled in the study were evaluated for clinical profile, angiographic profile, and the outcome. Results: A total of 3660 patients were enrolled in this study. There were 56.2% of males and 43.8% of females. Smoking as risk factor was noted in 69.6% of males and 7.9% of females, hypertension in 52.9% of males versus 65.4% of females, diabetes in 42.5% of males versus 60.7% of females, and obesity in 46.2% of males versus 57.3% of females. Male versus female mean body mass index was 24.7 versus 27.4, low-density lipoprotein 112.8 versus 123.7, high-sensitivity C-reactive protein 1.5 versus 2.9, and Lp(a) 274.9 versus 442.1, respectively. On coronary angiographic evaluation, male versus female single-vessel involvement was seen in 54.1% versus 58.8% of patients, double-vessel disease in 31.6% versus 27.6%, left main disease in 1.7% versus 3.6%, and spontaneous coronary artery dissection in 0.9% versus 1.5% patients, respectively. The overall mortality in males was 4.03% and 5.11% in females. Conclusion: Despite its atypical presentation, CAD has the worst outcome in women than men. Greater awareness of these gender-based differences will significantly improve the management and outcome of CAD in women.
引言:冠状动脉疾病(CAD)在两性中都会导致显著的发病率和死亡率,然而,CAD在女性中的重要性却被低估了。目的和目的:本研究旨在调查印度北部一个邦CADs在表现、评估和结果方面基于性别的差异。材料和方法:这是一项为期3年的前瞻性研究。纳入研究的所有CAD(急性冠状动脉综合征或慢性稳定型心绞痛)患者都进行了临床特征、血管造影特征和结果评估。结果:本研究共纳入3660名患者。其中男性占56.2%,女性占43.8%。吸烟是69.6%的男性和7.9%的女性的风险因素,高血压是52.9%的男性和65.4%的女性,糖尿病是42.5%的男性和60.7%的女性,肥胖是46.2%的男性和57.3%的女性。男性和女性的平均体重指数分别为24.7和27.4,低密度脂蛋白112.8和123.7,高敏C反应蛋白1.5和2.9,Lp(a)274.9和442.1。在冠状动脉造影评估中,男性和女性的单血管受累分别为54.1%和58.8%,双血管病变分别为31.6%和27.6%,左主干病变分别为1.7%和3.6%,自发性冠状动脉夹层分别为0.9%和1.5%。男性的总死亡率为4.03%,女性为5.11%。结论:尽管CAD表现不典型,但女性的预后比男性差。提高对这些基于性别的差异的认识将显著改善妇女CAD的管理和结果。
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引用次数: 1
Real time 3D-OCT predicts restenosis by identifying geographic miss between overlapping stents after complex multivessel percutaneous coronary intervention 实时3D-OCT通过识别复杂多血管经皮冠状动脉介入治疗后重叠支架之间的地理缺失预测再狭窄
Q4 Medicine Pub Date : 2020-04-01 DOI: 10.4103/heartindia.heartindia_51_19
Raghuram Palaparti, Gopala Koduru, Sudarshan Palaparti, P. S. Chowdary, P. Kondru, Somasekhar Ghanta, B. Mannuva, Prasad Maganti, Sasidhar Yendapalli
A 78-year-old male patient with a history of cerebrovascular accident and left hemiparesis presented with evolved inferior wall myocardial infarction and preserved left ventricle (LV) function. Coronary angiogram revealed triple-vessel disease. After heart team discussion, he was advised multivessel percutaneous coronary intervention (PCI). He underwent PCI to right coronary artery (2× sirolimus-eluting stent) in the first stage with good result. After 4 weeks, he again presented to the emergency department with acute coronary syndrome (ACS). He underwent imaging-guided left main (LM) bifurcation PCI (mini-crush technique) with 2 ×× everolimus-eluting stent (EES) across LM to left anterior descending artery (LAD) and 2 ×× EES in left circumflex artery (LCX). Real-time three-dimensional optical coherence tomography (3D-OCT) identified 1 mm geographic miss between overlapping stents in heavily calcified LAD. Cine fluoroscopy and intravascular ultrasound (IVUS) did not identify the same. In view of elderly age, already high contrast load, mild renal impairment, and low-risk OCT features, he was managed conservatively. He was doing well until 10 months after PCI, when he presented again to the emergency department with ACS and LV dysfunction. CAG showed critical in-stent restenosis (ISR) at the LAD stent overlap area. Other stents were all patent with mild ISR in LCx. He underwent PCI to LAD with 1 ×× EES. He is in follow-up for the last 1 year without any complaints and improved LV function. The availability of real-time 3D-OCT machines allowed us to easily identify “geographic miss” which is sometimes difficult to detect with cine flouroscopy or IVUS, particularly in heavily calcified vessels. This newer technology adds another dimension to intravascular imaging-guided PCI and has shown great promise particularly in complex and bifurcation PCI.
一名78岁男性患者,有脑血管意外和左偏瘫病史,表现为演变性下壁心肌梗死,左心室(LV)功能保持。冠状动脉造影显示有三血管病变。在心脏小组讨论后,建议他进行多血管经皮冠状动脉介入治疗(PCI)。他在第一阶段接受了右冠状动脉PCI(2×西罗莫司洗脱支架),效果良好。4周后,他再次因急性冠状动脉综合征(ACS)到急诊科就诊。他接受了影像学引导的左主干(LM)分支PCI(迷你挤压技术),使用2××依维莫司洗脱支架(EES)穿过LM到达左前降支(LAD),并在左旋支(LCX)使用2×。实时三维光学相干断层扫描(3D-OCT)在严重钙化的左前降支中发现重叠支架之间的1mm地理缺失。电影荧光透视和血管内超声(IVUS)没有发现相同的情况。考虑到年龄较大、造影剂负荷已经很高、轻度肾损伤和低风险OCT特征,对其进行了保守治疗。他一直表现良好,直到PCI术后10个月,他因急性冠脉综合征和左心室功能障碍再次出现在急诊科。CAG在左前降支支架重叠区显示严重的支架内再狭窄(ISR)。其他支架在LCx中均为轻度ISR。他接受了经皮冠状动脉介入治疗至左前降支,并伴有1××EES。在过去的一年里,他一直在随访,没有任何投诉,左心室功能也有所改善。实时3D-OCT机器的可用性使我们能够轻松识别“地理缺失”,这有时很难用电影荧光镜或IVUS检测到,尤其是在严重钙化的血管中。这项新技术为血管内成像引导PCI增加了另一个维度,并显示出巨大的前景,特别是在复杂和分叉PCI中。
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引用次数: 0
Safety and efficacy of transcatheter device closure of patent ductus arteriosus in pediatric patients: Long-term outcomes 儿童动脉导管未闭经导管封堵器的安全性和有效性:长期疗效
Q4 Medicine Pub Date : 2020-04-01 DOI: 10.4103/heartindia.heartindia_6_20
J. Shah, Dharmin Bhalodiya, Abhishek Pravinchandra, S. Saraiya
Aims: Patent ductus arteriosus (PDA) is among the most prevalent congenital heart diseases in current times. The aim of this study is to evaluate contemporarily the safety and efficacy of transcatheter device closure of PDA at long-term follow-up. Materials and Methods: Transcatheter closure of PDA was attempted in 205 children between 2008 and 2015 using the Amplatzer duct occlude (ADO). Ductal anatomy was accurately delineated on lateral and right anterior oblique view on aortic angiogram. All children underwent complete clinical evaluation, electrocardiography, chest X-rays, and echocardiography prior to discharge and at 1-month, 6-month, and annual follow-up thereafter. Results: Of a total of 205 cases, 64% were females; the mean age was 7.92 ± 3.61 years (1–17 years), while the mean weight was 16.68 ± 10.82 (5–41 kg). ADOs-I were used in all the cases. The procedure was successful in 99.03% of patients with excellent results. Two patients required surgical closure due to device-induced aortic obstruction and left pulmonary stenosis. There were no cases of procedural deaths, device embolization, device infection, and infective endocarditis. All children fared well at a median follow-up of 94 months with no complications. Conclusion: The long-term data showed that percutaneous transcatheter closure of PDA using ADO was safe and effective in pediatric population with minimal complications.
目的:动脉导管未闭(PDA)是当今最常见的先天性心脏病之一。本研究的目的是评估当代经导管装置关闭PDA在长期随访中的安全性和有效性。材料与方法:2008年至2015年间,我们对205名儿童采用Amplatzer导管闭塞术(ADO)对PDA进行了经导管封闭。在主动脉造影的侧位和右前斜位上准确地描绘了导管解剖。所有儿童在出院前以及出院后1个月、6个月和每年随访时均进行了完整的临床评估、心电图、胸部x线检查和超声心动图检查。结果:205例患者中,女性占64%;平均年龄为7.92±3.61岁(1 ~ 17岁),平均体重为16.68±10.82 (5 ~ 41 kg)。所有病例均使用ados - 1。手术成功率达99.03%,效果良好。2例患者因器械引起的主动脉阻塞和左肺狭窄需要手术关闭。没有手术死亡、器械栓塞、器械感染和感染性心内膜炎病例。在中位随访94个月期间,所有儿童均表现良好,无并发症。结论:长期资料显示,经皮经导管应用ADO封堵PDA安全有效,并发症少。
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引用次数: 1
Fetal echocardiography: A single-center tertiary care experience 胎儿超声心动图:单中心三级护理经验
Q4 Medicine Pub Date : 2020-04-01 DOI: 10.4103/heartindia.heartindia_8_20
A. Rashid, Shaheera Ajaz, H. Rather, Aabid A. Ahmed, Rabiya Khursheed, I. Hafeez, Iqbal Dar, N. Choh
Background: Although fetal echocardiography is established screening tool for the detection of cardiac anomalies, its utility and awareness remains less in less-developed areas of the world. There is no data from our region about the usage and outcome of fetal echocardiography. Aims and Objectives: To study the indications, referral patterns, and outcomes of fetal echocardiography. Materials and Methods: All pregnant women referred for fetal echocardiography from January 2017 to July 2018 were included in the study. Results: A total of 600 pregnant women underwent fetal echocardiography. The mean age of patients was 28 ± 4.2 years. The mean gestational age referred for fetal echo was 26 ± 4 weeks. Four hundred and twenty (70%) patients were more than 22 weeks of gestational age. Indications included maternal indications in 385 (64.2%) patients. The various maternal indications included bad obstetrical history in 180 (30%), pregestational diabetes in 100 (16.67%), congenital heart disease (CHD) in mother in 35 (5.83%), medication use during pregnancy in 15 (2.3%), and connective tissue disorder in mother in 55 (9.16%). Other indications included abnormal/not properly visualized cardiac chambers on anomaly scan in 50 (8.3%) and previous child with heart disease in 105 (17.5%). Different abnormalities detected included ventricular septal defect, pulmonary atresia intact septum each in 3 (0.5%); tetarology of fallot (TOF), tricuspid atresia, unbalanced atrioventricular canal defect with single ventricle, corrected the great arteries, fetal cardiac tumor, Ebstein anomaly, and total anomalous pulmonary venous connection each in 1 (0.16%); double outlet right ventricle pulmonary stenosis, hypoplastic left heart syndrome, compete heart block, fetal supraventricular tachycardia, and CoA each in 2 (0.33%) patients. Twenty-four of 600 (40 per 1000) screened fetal echos were abnormal. Seventeen (70.8%) patients were referred for an unsatisfactory/abnormal anomaly scan which were low-risk pregnancies. The highest yield of CHD was in patients who had been referred for abnormal fetal anomaly scan when compared with other referral indications (17 of 50 [34%] versus 7 of 550 [1.27%] in other indications; P = 0.0001). Conclusion: The most common indication for which fetal scan was abnormal routine ultrasound which was mostly low-risk pregnancies. Dedicated cardiac screening should be part of the routine anomaly scan. Detailed fetal echo should be done in all patients who have any doubt on anomaly scan. Greater awareness in our community is needed for proper referral timings of fetal echo.
背景:虽然胎儿超声心动图是检测心脏异常的筛查工具,但在世界欠发达地区,其实用性和意识仍然较少。我们地区没有关于胎儿超声心动图的使用和结果的数据。目的和目的:研究胎儿超声心动图的适应症、转诊模式和结果。材料与方法:2017年1月至2018年7月,所有接受胎儿超声心动图检查的孕妇均纳入研究。结果:共600名孕妇接受了胎儿超声心动图检查。患者平均年龄28±4.2岁。胎儿回声的平均胎龄为26±4周。420例(70%)患者的胎龄超过22周。适应症包括385例(64.2%)患者的产妇适应症。产妇的各种适应证包括:不良产科史180例(30%),妊娠期糖尿病100例(16.67%),母亲先天性心脏病35例(5.83%),孕期用药15例(2.3%),母亲结缔组织疾病55例(9.16%)。其他适应症包括50例(8.3%)异常扫描时心室异常或未正确显示,105例(17.5%)既往儿童有心脏病。不同异常包括室间隔缺损、肺闭锁、室间隔完整3例(0.5%);法洛特四联症(TOF)、三尖瓣闭锁、单心室房室管不平衡缺损、大动脉矫正、胎儿心脏肿瘤、Ebstein异常、全肺静脉连接异常各1例(0.16%);双出口右心室肺动脉狭窄、左心发育不全综合征、竞争性心脏传导阻滞、胎儿室上性心动过速和CoA各2例(0.33%)。600例胎儿超声检查中有24例(40 / 1000)异常。17例(70.8%)患者因不满意/异常异常扫描而转诊,为低危妊娠。与其他转诊指征相比,转诊胎儿异常扫描的患者冠心病发生率最高(50例中有17例[34%],而其他指征中550例中有7例[1.27%];P = 0.0001)。结论:常规超声异常是胎儿扫描最常见的指征,多为低危妊娠。专门的心脏筛查应该是常规异常扫描的一部分。所有对异常扫描有疑问的患者都应做详细的胎儿超声检查。我们的社区需要更多的意识,以适当的转介时间胎儿回声。
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引用次数: 0
Effect of nicorandil on short-term echocardiographic and acute angiographic outcomes in acute coronary syndrome patients undergoing percutaneous coronary intervention 尼可地尔对经皮冠状动脉介入治疗急性冠状动脉综合征患者短期超声心动图和急性血管造影结果的影响
Q4 Medicine Pub Date : 2020-04-01 DOI: 10.4103/heartindia.heartindia_19_20
A. Jha, M. Rohit
Context: Patients with acute coronary syndrome (ACS) often have the suboptimal results of percutaneous coronary intervention (PCI) despite adequate restoration of coronary patency. Aims: This study evaluated the utility of starting nicorandil before PCI in patients with ACS, in terms of acute angiographic and short-term echocardiographic outcomes. Settings and Design: It was a prospective, randomized, blinded, single-center trial; involving stable patients with recent ACS and no prior revascularization. Subjects and Methods: Patients started on intravenous (IV) nicorandil infusion or placebo at least 2 h before PCI, continued till 48 h after PCI. Echocardiographic parameters (left ventricular ejection fraction [LVEF], Wall Motion Score Index (WMSI) score, and myocardial performance index (MPI)) were assessed at baseline and at 4 weeks post-PCI. Thrombolysis in myocardial infarction (TIMI) flow grade and corrected TIMI frame count were assessed before and after PCI. The primary endpoints were improvement in regional wall motion abnormality, MPI, LVEF, and corrected TIMI frame count. The secondary endpoints were the major adverse cardiovascular event (MACE) (cardiac death, angina, myocardial infarction [MI], or revascularization) within 30 days, no reflow, slow flow, and periprocedural MI. Results: Fifty-five patients were recruited over 1 year, of which 13 patients were excluded. There were numerically lower but statistically nonsignificant improvement in slow flow and no reflow in nicorandil arm. Significant improvement in echocardiographic parameter of MPI was seen in nicorandil group at follow-up. There was no significant improvement in other echocardiographic parameters and MACE. Conclusions: In patients with ACS and a single-vessel disease on undergoing PCI for recent ACS, the use of IV nicorandil was associated with a significant improvement in MPI at 1-month follow-up. There was no significant difference in the acute angiographic parameters, MACE, LVEF, or wall motion score index.
背景:急性冠状动脉综合征(ACS)患者尽管冠状动脉通畅性得到了充分恢复,但经皮冠状动脉介入治疗(PCI)的结果往往并不理想。目的:本研究评估了急性冠脉综合征患者PCI前开始服用尼可地尔的急性血管造影和短期超声心动图结果。设置和设计:这是一项前瞻性、随机、盲法、单中心试验;涉及近期急性冠脉综合征且既往无血运重建的稳定患者。受试者和方法:患者在PCI前至少2小时开始静脉滴注尼可地尔或安慰剂,持续至PCI后48小时。在基线和PCI后4周评估超声心动图参数(左心室射血分数[LVEF]、壁运动评分指数(WMSI)评分和心肌性能指数(MPI))。PCI前后评估心肌梗死溶栓(TIMI)流量等级和校正TIMI帧计数。主要终点是改善局部壁运动异常、MPI、LVEF和校正TIMI帧数。次要终点是30天内的主要心血管不良事件(MACE)(心脏死亡、心绞痛、心肌梗死或血运重建)、无回流、缓慢血流和围手术期心肌梗死。结果:1年内招募了55名患者,其中13名患者被排除在外。尼可地尔组的慢流和无回流在数值上较低,但在统计学上无显著改善。随访时,尼可地尔组MPI的超声心动图参数有显著改善。其他超声心动图参数和MACE没有显著改善。结论:急性冠脉综合征和单血管疾病患者在接受PCI治疗时,静脉注射尼可地尔与1个月随访时MPI的显著改善有关。急性血管造影参数、MACE、LVEF或壁运动评分指数无显著差异。
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引用次数: 1
Left ventricular systolic function assessment with two-dimensional strain imaging among patients with rheumatic mitral stenosis 风湿性二尖瓣狭窄患者的二维应变成像评价左心室收缩功能
Q4 Medicine Pub Date : 2020-04-01 DOI: 10.4103/heartindia.heartindia_10_20
Amresh Singh, Amit Kumar, S. Vijay, Sunitha Vishwanathan
Introduction: Two-dimensional (2D) strain is a novel technique which evaluates left ventricular (LV) systolic functions more objectively and quantitatively and does not have the limitations seen in ejection fraction (EF), tissue Doppler imaging, and Doppler strain. In this study, we aimed to evaluate the role of 2D strain in the assessment of LV systolic function and the relationship between the presence of atrial fibrillation (AF) and LV dysfunction in patients with mitral stenosis (MS). Materials and Methods: This study is a cross-sectional study. The 2D strain was obtained from LV apical LAX, 4C, and 2C view. Peak LV longitudinal systolic strain was calculated for apical LCX, 4C, and 2C view, and global LV systolic strain was calculated by averaging the three apical views. Results: A total of thirty patients were enrolled in the study. They included 24 (80%) females and 6 (20%) males. There were 11 patients (36.7%) had AF and 21 patients (63.3%) had sinus rhythm. There were mean mitral valve area 1.17 cm2 (by planimetry) and 1.19 cm2 (by pressure half-time), mean mitral valve gradient 12.0 mmHg, mean peak gradient 22 mmHg, and mean right ventricular systolic pressure (50.6 vs. 37.4 mmHg) compared to sinus group. In this study, the mean ALAX LSS (−15.12), mean A4C LSS (−14.65), mean A2C LSS (−13.89), and mean GLOBAL LSS (−14.52) were statistically significant (P < 0.001) lower than the control group. Among AF groups, there were statistically significant (P < 0.05) lower A2C LSS and GLOBAL LSS, but there was no significant difference in ALAX LSS and A4C LSS in both groups. Conclusion: Despite normal LV dimensions and EF, there was a highly significant lower (P < 0.001) global longitudinal systolic strain (GLSS) in MS patients compared to healthy controls. Patients with AF had significantly lower GLSS value (P < 0.05) than the sinus rhythm group among patients with MS.
二维应变是一种较客观定量评价左室收缩功能的新技术,不存在射血分数(EF)、组织多普勒成像和多普勒应变的局限性。在本研究中,我们旨在评估2D应变在二尖瓣狭窄(MS)患者左室收缩功能评估中的作用,以及心房颤动(AF)的存在与左室功能障碍的关系。材料与方法:本研究为横断面研究。2D菌株分别从LV顶端LAX、4C和2C视图获得。计算顶端LCX、4C和2C视点的左室纵向收缩应变峰值,计算三个顶点视点的左室整体收缩应变平均值。结果:共有30例患者入组研究。其中女性24例(80%),男性6例(20%)。房颤11例(36.7%),窦性心律21例(63.3%)。平均二尖瓣面积1.17 cm2(平面测量法)和1.19 cm2(压力半时间法),平均二尖瓣梯度12.0 mmHg,平均峰值梯度22 mmHg,平均右心室收缩压(50.6 vs 37.4 mmHg)。本研究中,ALAX平均LSS(- 15.12)、A4C平均LSS(- 14.65)、A2C平均LSS(- 13.89)、GLOBAL平均LSS(- 14.52)均低于对照组,差异均有统计学意义(P < 0.001)。AF组间,A2C LSS、GLOBAL LSS降低有统计学意义(P < 0.05), ALAX LSS、A4C LSS降低无统计学意义(P < 0.05)。结论:尽管左室尺寸和EF正常,但MS患者的整体纵向收缩应变(GLSS)显著低于健康对照组(P < 0.001)。房颤组GLSS值明显低于窦性心律组(P < 0.05)。
{"title":"Left ventricular systolic function assessment with two-dimensional strain imaging among patients with rheumatic mitral stenosis","authors":"Amresh Singh, Amit Kumar, S. Vijay, Sunitha Vishwanathan","doi":"10.4103/heartindia.heartindia_10_20","DOIUrl":"https://doi.org/10.4103/heartindia.heartindia_10_20","url":null,"abstract":"Introduction: Two-dimensional (2D) strain is a novel technique which evaluates left ventricular (LV) systolic functions more objectively and quantitatively and does not have the limitations seen in ejection fraction (EF), tissue Doppler imaging, and Doppler strain. In this study, we aimed to evaluate the role of 2D strain in the assessment of LV systolic function and the relationship between the presence of atrial fibrillation (AF) and LV dysfunction in patients with mitral stenosis (MS). Materials and Methods: This study is a cross-sectional study. The 2D strain was obtained from LV apical LAX, 4C, and 2C view. Peak LV longitudinal systolic strain was calculated for apical LCX, 4C, and 2C view, and global LV systolic strain was calculated by averaging the three apical views. Results: A total of thirty patients were enrolled in the study. They included 24 (80%) females and 6 (20%) males. There were 11 patients (36.7%) had AF and 21 patients (63.3%) had sinus rhythm. There were mean mitral valve area 1.17 cm2 (by planimetry) and 1.19 cm2 (by pressure half-time), mean mitral valve gradient 12.0 mmHg, mean peak gradient 22 mmHg, and mean right ventricular systolic pressure (50.6 vs. 37.4 mmHg) compared to sinus group. In this study, the mean ALAX LSS (−15.12), mean A4C LSS (−14.65), mean A2C LSS (−13.89), and mean GLOBAL LSS (−14.52) were statistically significant (P < 0.001) lower than the control group. Among AF groups, there were statistically significant (P < 0.05) lower A2C LSS and GLOBAL LSS, but there was no significant difference in ALAX LSS and A4C LSS in both groups. Conclusion: Despite normal LV dimensions and EF, there was a highly significant lower (P < 0.001) global longitudinal systolic strain (GLSS) in MS patients compared to healthy controls. Patients with AF had significantly lower GLSS value (P < 0.05) than the sinus rhythm group among patients with MS.","PeriodicalId":32147,"journal":{"name":"Heart India","volume":"8 1","pages":"93 - 97"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47851011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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