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Epidemiology of primary bone tumours in Nigeria: a systematic review 尼日利亚原发性骨肿瘤的流行病学:一项系统综述
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.17159/2309-8309/2022/v21n3a5
T. Koyejo, O. Olusunmade, O. Olufemi
BACKGROUND: Primary bone tumours, although rare, are an important rising cause of morbidity and mortality in Africa. Late presentation, delayed diagnosis and failure to obtain consent for surgical procedures are important causes of loss of limb and life especially in the West African subregion. Existing data on primary bone tumours in Nigeria have been based on studies performed at various regional levels. The aim of this study is to determine the epidemiological pattern of primary bone tumours in Nigeria in general, including demographics, predominant tumour types and predominant skeletal location by reviewing existing data METHODS: A search of the following databases: University of Edinburgh Library, PubMed, CINAHL and SCOPUS from 2000 till January 2021 following PRISMA guidelines was conducted to identify studies conducted in Nigeria with relevant epidemiological data on primary bone tumours in Nigeria RESULTS: The search yielded a total of 952 hits from which seven hospital-based retrospective studies met the inclusion criteria for review. The estimated incidence rate of primary bone tumours ranged from 0.08 to 0.31 per 100 000 population. All studies showed a male preponderance. The peak age group of individuals presenting with both benign and malignant primary bone tumours was 11-20 years. Overall, benign tumours were more common. Osteochondromas were the most common benign tumours, while the commonest malignant tumours identified were osteosarcomas. The most common location for both benign and malignant tumours were the tibia and fibula CONCLUSION: Nigeria shares some similar epidemiological characteristics of primary bone tumour with other countries; however, some peculiar differences have been identified in this study. Population-based studies are required to obtain more accurate epidemiological data about this disease Level of evidence: Level 2
背景:原发性骨肿瘤虽然罕见,但在非洲是发病率和死亡率上升的重要原因。姗姗来迟、诊断延误和未能获得手术同意是肢体和生命丧失的重要原因,特别是在西非分区域。尼日利亚关于原发性骨肿瘤的现有数据是根据在各个区域级别进行的研究得出的。本研究的目的是通过回顾现有数据确定尼日利亚原发性骨肿瘤的流行病学模式,包括人口统计学、主要肿瘤类型和主要骨骼位置。方法:搜索以下数据库:遵循PRISMA指南,从2000年至2021年1月,爱丁堡大学图书馆、PubMed、CINAHL和SCOPUS进行了检索,以确定在尼日利亚进行的具有尼日利亚原发性骨肿瘤相关流行病学数据的研究。结果:检索共产生952个结果,其中7个基于医院的回顾性研究符合纳入标准。原发性骨肿瘤的估计发病率为每10万人0.08至0.31人。所有的研究都显示男性占优势。出现良性和恶性原发性骨肿瘤的高峰年龄组为11-20岁。总体而言,良性肿瘤更为常见。骨软骨瘤是最常见的良性肿瘤,而最常见的恶性肿瘤是骨肉瘤。结论:尼日利亚原发性骨肿瘤的流行病学特征与其他国家相似;然而,在这项研究中发现了一些特殊的差异。需要开展以人群为基础的研究,以获得有关该病更准确的流行病学数据
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引用次数: 0
Splints and immobilisation approaches used for second to fifth metacarpal fractures: a systematic review 夹板和固定方法用于第二至第五掌骨骨折:系统回顾
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.17159/2309-8309/2022/v21n2a3
M. Keller, R. Barnes, C. Brandt, L. Hepworth
BACKGROUND: The second to fifth metacarpal fractures are immobilised with splints, plaster of Paris (POP) or buddy strapping for a period of time. However, no recent evidence-based splinting and immobilisation programme exists for the management thereof, leaving a gap in the literature to inform clinical practice. This review aimed to review, appraise and collate the literature on splints and immobilisation approaches used for second to fifth metacarpal fractures after surgical and conservative management in adults aged 20 to 59 years. METHODS: The review included experimental study designs, quasi-experimental studies, cohort studies and case-control studies from January 2008 to September 2018. Two reviewers independently screened, selected, appraised and extracted data from the included studies. Preferred reporting items for systematic reviews and meta-analysis (PRISMA) guided the reporting. Joanna Briggs Institute (jBl) critical appraisal tools were used to assess the risk of bias for each included study. RESULTS: Database searches generated 1 005 articles with ten additional articles found on Google Scholar. Ten articles were included: two randomised controlled trials (RCTs), one quasi-RCT, four prospective studies, one retrospective record review, one retrospective study and one comparative study with descriptive reporting of the results. CONCLUSION: High level 1b evidence suggests that no reduction, a soft wrap and buddy strapping for three weeks with early active finger and wrist mobilisation are effective for individuals who sustained boxer's fractures with < 70° angulation. To guide clinical practice, high-level research is needed to determine the immobilisation of second to fifth metacarpal fracture types. Level of evidence: Level 2
背景:第二至第五掌骨骨折用夹板、巴黎石膏(POP)或好友绑带固定一段时间。然而,最近没有基于证据的夹板和固定方案存在于其管理中,在文献中留下空白,以告知临床实践。本综述旨在回顾、评估和整理关于夹板和固定入路用于20 - 59岁成人手术和保守治疗后第二至第五掌骨骨折的文献。方法:纳入2008年1月至2018年9月的实验研究设计、准实验研究、队列研究和病例对照研究。两位审稿人独立筛选、选择、评价和提取纳入研究的数据。系统评价和荟萃分析(PRISMA)的首选报告项目指导了报告。使用乔安娜布里格斯研究所(jBl)的关键评估工具来评估每个纳入研究的偏倚风险。结果:数据库搜索产生了1005篇文章,另外在谷歌Scholar上发现了10篇文章。纳入10篇文章:2篇随机对照试验(rct)、1篇准rct、4篇前瞻性研究、1篇回顾性记录综述、1篇回顾性研究和1篇描述性结果比较研究。结论:高水平1b证据表明,对于持续的拳击手骨折< 70°角度的患者,不复位,软包和好友绑扎三周,早期活动手指和手腕活动是有效的。为了指导临床实践,需要高水平的研究来确定第二至第五掌骨骨折类型的固定。证据等级:二级
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引用次数: 1
Retrospective audit of serum vitamin D levels in patients who underwent Latarjet procedure for anterior shoulder instability 肩前路不稳行拉塔捷手术患者血清维生素D水平的回顾性分析
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.17159/2309-8309/2022/v21n4a4
A. Rachuene, R. Dey, S. de Villiers, K. Berry, M. Mulder, J. Du Plessis, S. Roche
BACKGROUND: The aim of this study was to review vitamin D levels in patients who underwent Latarjet procedures at a tertiary teaching hospital and a private clinic. METHODS: A retrospective review of clinical and radiological records was performed for 22 patients who underwent Latarjet procedure between November 2017 and June 2019. Postoperative vitamin D levels were retrieved and classified into sufficient (> 75 nmol/L), insufficient (25-75 nmol/L), and deficient (< 25 nmol/L) groups. Two observers assessed radiographic images of the patients at six weeks and three months after surgery. Any bone resorption, fracture and nonunion were reported, and interobserver reliability was analysed using the intraclass correlation coefficient (ICC). RESULTS: The median age was 20.5 years and was predominantly male. A little more than two-thirds (68.1%) of the patients were found to have insufficient or deficient levels of vitamin D. One patient from the insufficient group had postoperative bone resorption. Good interobserver reliability was observed with the ICC value being 0.86. CONCLUSION: This study found a prevalence of insufficient/deficient vitamin D levels in young patients undergoing a Latarjet procedure. This study serves as a reminder to orthopaedic surgeons that vitamin D deficiency is prevalent among patients undergoing Latarjet Level of evidence: Level 4.
背景:本研究的目的是回顾在三级教学医院和私人诊所接受Latarjet手术的患者的维生素D水平。方法:回顾性分析2017年11月至2019年6月期间接受Latarjet手术的22例患者的临床和放射学记录。术后恢复维生素D水平,并将其分为充足组(75 nmol/L)、不足组(25-75 nmol/L)和缺乏组(< 25 nmol/L)。两名观察员评估了患者术后6周和3个月的放射图像。报告任何骨吸收、骨折和骨不连,并使用类内相关系数(ICC)分析观察者间的信度。结果:中位年龄为20.5岁,以男性为主。超过三分之二(68.1%)的患者发现维生素d不足或缺乏。维生素d不足组中有1例患者术后出现骨吸收。观察到良好的观察者间信度,ICC值为0.86。结论:本研究发现在接受Latarjet手术的年轻患者中普遍存在维生素D水平不足/缺乏。这项研究提醒骨科医生,维生素D缺乏症在接受Latarjet手术的患者中很普遍。
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引用次数: 0
Data and decision making – from odd to artificial 数据和决策——从奇怪到人为
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.17159/2309-8309/2022/v21n2a0
L. Marais
With my term as Editor-in-Chief of the SAOJ coming to an end soon, I cannot help but reflect on some of my past experiences in this role. Perhaps the most challenging (and satisfying) was the need to get to grips with some of the more intricate aspects of research methodology and statistics. At first glance, these concepts seem fairly straightforward, but almost ubiquitously become exceedingly complex the harder you look. The odds ratio (OR) is an excellent case in point. There are a number of ways in which the measure of association between an exposure and an outcome can be expressed. ORs are probably the most commonly used. The current emphasis on reporting 95% confidence intervals (CI), rather than only p-values, has resulted in us seeing and doing a lot more logistic regression. Along with the 95% CI, the statistical program also provides the OR, which is then reported in our results. Now, ORs are tricky things. To justify this statement, I am going to have to go way back to the start, where all good research should start, with the definitions. A ratio is simply a number obtained by dividing one number by another number, and there is not necessarily a relationship between the numerator and denominator. A proportion is a ratio that relates a part to a whole, thus there is a relationship between the numerator and denominator. Rate is a proportion where the denominator also takes into account another dimension, typically time. Defining probability (P) is a minefield, but for our purposes, we will limit it to the measure of the likelihood that an event will occur. With the basics out of the way, let us delve a little deeper. Relative risk (RR), also known as the risk ratio, is a descriptive statistic commonly used in analytical studies. Risk can be defined as the probability of the outcome of interest occurring. RR is therefore essentially a ratio of proportions. In statistical terms, RR is equal to the event rate in the exposed group divided by the event rate in the non-exposed (control) group (Figure 1). For example, imagine we are performing a study comparing the risk of developing infection following grade III open fractures when antibiotics are given within an hour of the injury (treatment group) or not (control group). If 5 out of 100 patients in the treatment group and 20 out of 100 patients in the control group get an infection, we have a relative risk of 0.25. RR = 0.25 means exposed patients (i.e., in the treatment group) are 0.25 times as likely to develop the outcome of interest. We could also state that patients receiving antibiotics within an hour were 75% (0.75 = 1 − 0.25) less likely to develop infection. As clinicians we generally prefer to think in terms of probabilities and relative risk. The other commonly used descriptive statistic to report measure of association is the odds ratio (OR). Odds can be defined as the relative probability of the outcome of interest occurring. So, what is this probability relative to? – the probab
随着我作为SAOJ总编辑的任期即将结束,我不禁回顾了我过去在这个角色上的一些经历。也许最具挑战性(也是最令人满意的)是需要掌握研究方法和统计的一些更复杂的方面。乍一看,这些概念似乎相当简单,但你越仔细看,它们几乎无处不在地变得极其复杂。比值比(OR)就是一个很好的例子。有许多方法可以表达暴露与结果之间的联系。or可能是最常用的。目前强调报告95%置信区间(CI),而不仅仅是p值,这导致我们看到并做了更多的逻辑回归。除了95% CI,统计程序还提供OR,然后在我们的结果中报告。现在,手术室是棘手的事情。为了证明这一说法是正确的,我将不得不回到起点,所有好的研究都应该从定义开始。比率只是一个数字除以另一个数字得到的数字,分子和分母之间不一定有关系。比例是部分与整体的比例,因此分子和分母之间存在关系。速率是一个比例,其分母还考虑了另一个维度,通常是时间。定义概率(P)是一个雷区,但出于我们的目的,我们将其限制为度量事件发生的可能性。有了这些基础知识,让我们深入研究一下。相对危险度(RR),又称风险比,是分析研究中常用的描述性统计量。风险可以定义为利息结果发生的概率。因此,RR本质上是一个比例比率。从统计学角度来看,RR等于暴露组的事件发生率除以未暴露组(对照组)的事件发生率(图1)。例如,假设我们正在进行一项研究,比较在受伤后一小时内给予抗生素(治疗组)或未给予抗生素(对照组)的III级开放性骨折发生感染的风险。如果治疗组100名患者中有5名感染,对照组100名患者中有20名感染,我们的相对风险为0.25。RR = 0.25意味着暴露患者(即治疗组)发生感兴趣结果的可能性是对照组的0.25倍。我们还可以说,在一小时内接受抗生素治疗的患者发生感染的可能性降低了75%(0.75 = 1 - 0.25)。作为临床医生,我们通常更喜欢从概率和相对风险的角度来思考。另一种常用的描述性统计方法是比值比(OR)。赔率可以定义为利益结果发生的相对概率。那么,这个概率相对于什么呢?——结果不发生的概率。换句话说,概率表示事件发生的概率与事件不发生的概率之比。概率在数学上可以定义为(P/1 - P)。OR是比值的比值等于受辐射组的结果概率除以未受辐射对照组的结果概率。OR < 1表示感兴趣的结果发生的几率降低,OR < 0 1表示几率增加。因此,在我们的开放性骨折示例研究中,OR为0.21。这意味着在接受抗生素治疗的人群中,感染的几率(而不是风险)降低了79%。如果OR是3.8,这意味着发生兴趣结果的几率增加了3.8倍。为了完整起见,我还将提到需要治疗的数量(NNT),它本质上是需要接受暴露以防止一种不想要的结果的患者数量。它被定义为绝对风险降低(ARR)的倒数。ARR等于对照组的事件发生率(CER)减去暴露组的事件发生率(EER)。在这一点上,反思ORs的起源可能是有用的。第一个基本原理与研究设计有关。在横断面研究中,RR可由患病率计算。在队列研究中,RR可通过发病率计算。如果在病例对照研究中无法获得发病率或患病率,则or可能是提供相关性测量指标的唯一选择重要的是要记住,病例对照研究通常用于研究罕见疾病或事件。为什么这是相关的,希望很快就会有更多的意义。ORs存在的第二个原因本质上是统计上的,而且有些复杂。基本上,即使在队列研究中,逻辑回归也提供了OR而不是RR,因为在数学建模过程中收敛问题的频率。 随着我作为SAOJ总编辑的任期即将结束,我不禁回顾了我过去在这个角色上的一些经历。也许最具挑战性(也是最令人满意的)是需要掌握研究方法和统计的一些更复杂的方面。乍一看,这些概念似乎相当简单,但你越仔细看,它们几乎无处不在地变得极其复杂。比值比(OR)就是一个很好的例子。有许多方法可以表达暴露与结果之间的联系。or可能是最常用的。目前强调报告95%置信区间(CI),而不仅仅是p值,这导致我们看到并做了更多的逻辑回归。除了95% CI,统计程序还提供OR,然后在我们的结果中报告。现在,手术室是棘手的事情。为了证明这一说法是正确的,我将不得不回到起点,所有好的研究都应该从定义开始。比率只是一个数字除以另一个数字得到的数字,分子和分母之间不一定有关系。比例是部分与整体的比例,因此分子和分母之间存在关系。速率是一个比例,其分母还考虑了另一个维度,通常是时间。定义概率(P)是一个雷区,但出于我们的目的,我们将其限制为度量事件发生的可能性。有了这些基础知识,让我们深入研究一下。相对危险度(RR),又称风险比,是分析研究中常用的描述性统计量。风险可以定义为利息结果发生的概率。因此,RR本质上是一个比例比率。从统计学角度来看,RR等于暴露组的事件发生率除以未暴露组(对照组)的事件发生率(图1)。例如,假设我们正在进行一项研究,比较在受伤后一小时内给予抗生素(治疗组)或未给予抗生素(对照组)的III级开放性骨折发生感染的风险。如果治疗组100名患者中有5名感染,对照组100名患者中有20名感染,我们的相对风险为0.25。RR = 0.25意味着暴露患者(即治疗组)发生感兴趣结果的可能性是对照组的0.25倍。我们还可以说,在一小时内接受抗生素治疗的患者发生感染的可能性降低了75%(0.75 = 1 - 0.25)。作为临床医生,我们通常更喜欢从概率和相对风险的角度来思考。另一种常用的描述性统计方法是比值比(OR)。赔率可以定义为利益结果发生的相对概率。那么,这个概率相对于什么呢?——结果不发生的概率。换句话说,概率表示事件发生的概率与事件不发生的概率之比。概率在数学上可以定义为(P/1 - P)。OR是比值的比值等于受辐射组的结果概率除以未受辐射对照组的结果概率。OR < 1表示感兴趣的结果发生的几率降低,OR < 0 1表示几率增加。因此,在我们的开放性骨折示例研究中,OR为0.21。这意味着在接受抗生素治疗的人群中,感染的几率(而不是风险)降低了79%。如果OR是3.8,这意味着发生兴趣结果的几率增加了3.8倍。为了完整起见,我还将提到需要治疗的数量(NNT),它本质上是需要接受暴露以防止一种不想要的结果的患者数量。它被定义为绝对风险降低(ARR)的倒数。ARR等于对照组的事件发生率(CER)减去暴露组的事件发生率(EER)。在这一点上,反思ORs的起源可能是有用的。第一个基本原理与研究设计有关。在横断面研究中,RR可由患病率计算。在队列研究中,RR可通过发病率计算。如果在病例对照研究中无法获得发病率或患病率,则or可能是提供相关性测量指标的唯一选择重要的是要记住,病例对照研究通常用于研究罕见疾病或事件。为什么这是相关的,希望很快就会有更多的意义。ORs存在的第二个原因本质上是统计上的,而且有些复杂。基本上,即使在队列研究中,逻辑回归也提供了OR而不是RR,因为在数学建模过程中收敛问题的频率。 什么是收敛问题?这个解释超出了本文的范围,也超出了我的理解范围。这与回归的目的是最大化可能性(通过发现)有关
{"title":"Data and decision making – from odd to artificial","authors":"L. Marais","doi":"10.17159/2309-8309/2022/v21n2a0","DOIUrl":"https://doi.org/10.17159/2309-8309/2022/v21n2a0","url":null,"abstract":"With my term as Editor-in-Chief of the SAOJ coming to an end soon, I cannot help but reflect on some of my past experiences in this role. Perhaps the most challenging (and satisfying) was the need to get to grips with some of the more intricate aspects of research methodology and statistics. At first glance, these concepts seem fairly straightforward, but almost ubiquitously become exceedingly complex the harder you look. The odds ratio (OR) is an excellent case in point. There are a number of ways in which the measure of association between an exposure and an outcome can be expressed. ORs are probably the most commonly used. The current emphasis on reporting 95% confidence intervals (CI), rather than only p-values, has resulted in us seeing and doing a lot more logistic regression. Along with the 95% CI, the statistical program also provides the OR, which is then reported in our results. Now, ORs are tricky things. To justify this statement, I am going to have to go way back to the start, where all good research should start, with the definitions. A ratio is simply a number obtained by dividing one number by another number, and there is not necessarily a relationship between the numerator and denominator. A proportion is a ratio that relates a part to a whole, thus there is a relationship between the numerator and denominator. Rate is a proportion where the denominator also takes into account another dimension, typically time. Defining probability (P) is a minefield, but for our purposes, we will limit it to the measure of the likelihood that an event will occur. With the basics out of the way, let us delve a little deeper. Relative risk (RR), also known as the risk ratio, is a descriptive statistic commonly used in analytical studies. Risk can be defined as the probability of the outcome of interest occurring. RR is therefore essentially a ratio of proportions. In statistical terms, RR is equal to the event rate in the exposed group divided by the event rate in the non-exposed (control) group (Figure 1). For example, imagine we are performing a study comparing the risk of developing infection following grade III open fractures when antibiotics are given within an hour of the injury (treatment group) or not (control group). If 5 out of 100 patients in the treatment group and 20 out of 100 patients in the control group get an infection, we have a relative risk of 0.25. RR = 0.25 means exposed patients (i.e., in the treatment group) are 0.25 times as likely to develop the outcome of interest. We could also state that patients receiving antibiotics within an hour were 75% (0.75 = 1 − 0.25) less likely to develop infection. As clinicians we generally prefer to think in terms of probabilities and relative risk. The other commonly used descriptive statistic to report measure of association is the odds ratio (OR). Odds can be defined as the relative probability of the outcome of interest occurring. So, what is this probability relative to? – the probab","PeriodicalId":32220,"journal":{"name":"SA Orthopaedic Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67480708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Access gate-related lower limb fractures in children and adolescents: a review of injury patterns and evaluation of associated injuries 儿童和青少年通道门相关下肢骨折:损伤模式的回顾和相关损伤的评估
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.17159/2309-8309/2022/v21n4a1
M. P. Phala, P. Rachuene, Bongani Socutshana, ¹. Khetani, S. Bila³
BACKGROUND: Lower limb fractures occurring in and around the home environment and caused by collapsing access gates present frequently to our emergency unit. There is currently limited literature evaluating injuries resulting from access gate accidents. The aim of this study was to evaluate the patterns of lower limb fractures, management options offered and concomitant injuries in children as well as adolescents presenting with access gate-related lower limb traumas. METHODS: A retrospective cross-sectional review of 43 children with 46 lower limb fractures was conducted between 1 January 2017 and 31 December 2020. Hospital records and radiology archives of all children and adolescents under 12 years of age (24 males and 8 females) with lower limb fractures sustained following an access gate injury were reviewed and included for analysis. Data was analysed descriptively using SAS (SAS Institute Inc, Carey, NC, USA), Release 9.4. RESULTS: The prevalence of access gate-related injuries for all lower limb fractures in children and adolescents treated during the four-year period was 11%. The findings revealed that femur fractures are more common, accounting for 50.0% of the cases. The majority of cases were of patients younger than 6 years (71.9%), and predominantly affecting males (3:1). The fractures occurred in a home environment and were commonly related to non-motorised gates, in 93.8% of cases. The oblique fracture patterns comprised 40.6% of the fractures, and 68.8% of the fractures were located in the diaphysis. Open fractures constituted 50.0% of the tibia fractures. Mild head injuries associated with lower limb fractures were observed in 12.5% of the cases. CONCLUSION: The results demonstrated the prevalence of lower limb fractures above all injuries related to access gates. The majority of the injuries observed in this study occurred in manually operated gates, and commonly affected younger patients. In light of these findings, further studies are required into the reasons for these injuries and preventative measures Level of evidence: Level 4.
背景:下肢骨折发生在家庭环境和周围,并引起塌陷的入口门经常出现在我们的急诊室。目前评价出入口事故造成的伤害的文献有限。本研究的目的是评估儿童和青少年出现与通道门相关的下肢创伤的下肢骨折模式、治疗方案和伴随损伤。方法:对2017年1月1日至2020年12月31日期间43例下肢骨折的儿童进行回顾性横断面分析。我们回顾了所有12岁以下儿童和青少年(24名男性和8名女性)在通道门损伤后下肢骨折的医院记录和放射学档案,并将其纳入分析。使用SAS (SAS Institute Inc, Carey, NC, USA), Release 9.4对数据进行描述性分析。结果:在四年治疗期间,所有儿童和青少年下肢骨折的通道门相关损伤发生率为11%。结果显示,股骨骨折更为常见,占病例的50.0%。以6岁以下患者居多(71.9%),以男性为主(3:1)。骨折发生在家庭环境中,通常与非机动门有关,占93.8%。斜向骨折占40.6%,骨干骨折占68.8%。开放性骨折占胫骨骨折的50.0%。12.5%的病例出现轻度头部损伤合并下肢骨折。结论:下肢骨折的发生率高于所有与通道门相关的损伤。本研究中观察到的大多数损伤发生在手动操作的门,通常影响年轻患者。根据这些发现,需要进一步研究这些伤害的原因和预防措施。证据等级:四级。
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引用次数: 0
A computer tomography-based anthropomorphic study of forearm osteology: implications for prosthetic design 基于计算机断层扫描的前臂骨病拟人化研究:对假体设计的启示
Q4 Medicine Pub Date : 2021-08-31 DOI: 10.17159/2309-8309/2021/v20n3a5
H. Pretorius, N. Ferreira, M. Burger
ABSTRACT BACKGROUND: The aim of this study was to accurately establish the variability in the anatomy of the radius and ulna in the context of the design of an intramedullary nail for both bones METHODS: Forearm computed tomography scans were used to measure the specific internal and external anatomy of the radius and ulna in adult patients. Patients with fractures or dislocations involving either the radius and/or ulna were excluded RESULTS: A total of 97 scans, comprising 84% male and 16% female patients, were included. The mean radius length was 238.43±18.38 mm (95% CI 234.60-241.74 mm). The mean curvature was an arc with a radius of 561.43±93.49 mm (95% CI 543.09-580.78 mm). The smallest measurement of the canal width was 5.17 mm (95% CI 4.87-5.47 mm). The ulna showed a mean length of 259.90±19.88 mm (95% CI 255.89-263.91 mm). The smallest measurement of the canal width was 4.80±1.30 mm (95% CI 4.53-5.87 mm). The mean proximal shaft angle was 11.39±3.30° (95% CI 10.76-12.82° CONCLUSION: This computed tomography scan-based anthropomorphic study has identified novel anatomical features and associations of human forearm bones. This information will be used in the design and manufacture of anatomic intramedullary devices to better manage radius and ulna fractures or pathology Level of evidence: Level 4 Keywords: radius, ulna, anatomy, osteology, radius of curvature, intramedullary design
摘要背景:本研究的目的是在设计两块骨头的髓内钉的背景下,准确地确定桡骨和尺骨解剖结构的可变性。排除桡骨和/或尺骨骨折或脱位的患者。结果:共有97次扫描,包括84%的男性和16%的女性患者。平均半径长度为238.43±18.38 mm(95%CI 234.60-241.74 mm)。平均曲率为一条半径为561.43±93.49 mm的圆弧(95%CI 543.09-580.78 mm)。管宽度的最小测量值为5.17mm(95%CI 4.87-5.47mm)。尺骨的平均长度为259.90±19.88 mm(95%CI 255.89-263.91 mm)。管宽度的最小测量值为4.80±1.30 mm(95%CI 4.53-5.87 mm)。平均近端轴角为11.39±3.30°(95%CI 10.76-12.82°结论:这项基于计算机断层扫描的拟人化研究已经确定了人类前臂骨骼的新解剖特征和关联。这些信息将用于解剖髓内装置的设计和制造,以更好地管理桡骨和尺骨骨折或病理学证据级别:4级关键词:桡骨、尺骨、解剖学、骨学、放射学弯曲ius,髓内设计
{"title":"A computer tomography-based anthropomorphic study of forearm osteology: implications for prosthetic design","authors":"H. Pretorius, N. Ferreira, M. Burger","doi":"10.17159/2309-8309/2021/v20n3a5","DOIUrl":"https://doi.org/10.17159/2309-8309/2021/v20n3a5","url":null,"abstract":"ABSTRACT BACKGROUND: The aim of this study was to accurately establish the variability in the anatomy of the radius and ulna in the context of the design of an intramedullary nail for both bones METHODS: Forearm computed tomography scans were used to measure the specific internal and external anatomy of the radius and ulna in adult patients. Patients with fractures or dislocations involving either the radius and/or ulna were excluded RESULTS: A total of 97 scans, comprising 84% male and 16% female patients, were included. The mean radius length was 238.43±18.38 mm (95% CI 234.60-241.74 mm). The mean curvature was an arc with a radius of 561.43±93.49 mm (95% CI 543.09-580.78 mm). The smallest measurement of the canal width was 5.17 mm (95% CI 4.87-5.47 mm). The ulna showed a mean length of 259.90±19.88 mm (95% CI 255.89-263.91 mm). The smallest measurement of the canal width was 4.80±1.30 mm (95% CI 4.53-5.87 mm). The mean proximal shaft angle was 11.39±3.30° (95% CI 10.76-12.82° CONCLUSION: This computed tomography scan-based anthropomorphic study has identified novel anatomical features and associations of human forearm bones. This information will be used in the design and manufacture of anatomic intramedullary devices to better manage radius and ulna fractures or pathology Level of evidence: Level 4 Keywords: radius, ulna, anatomy, osteology, radius of curvature, intramedullary design","PeriodicalId":32220,"journal":{"name":"SA Orthopaedic Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46256652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Malignant transformation in an 11-year-old child with multiple hereditary exostosis 一例11岁儿童多发性遗传性外泌体病的恶性转化
Q4 Medicine Pub Date : 2021-08-31 DOI: 10.17159/2309-8309/2021/v20n3a8
Janet L de Stadler, N. Kruger, Shivani Singh, E. Banderker, S. Dix-Peek, K. Pillay
ABSTRACT BACKGROUND: Multiple hereditary exostosis (MHE) is a rare autosomal dominant disorder predisposing to the development of multiple osteochondromas. Malignant transformation is an uncommon complication of osteochondromas and is especially rare in the paediatric population. Making a diagnosis of malignant transformation is recognised as a challenge globally METHODS: We obtained informed consent and ethics approval prior to reviewing the hospital file, radiology and pathology of our index patient, as well as conducting a directed literature search RESULTS: An 11-year-old male with MHE presented with new onset pain in the right leg with an associated inability to weight bear. Plain radiographs and magnetic resonance imaging (MRI) showed features consistent with malignant transformation. The child underwent a Malawer 1 resection of the proximal fibula with no complications. The pathology confirmed a grade 1 secondary peripheral chondrosarcoma (CS) arising in an osteochondroma The rate of malignant transformation in MHE is as high as 36.3% in select specialist tertiary centres. Ninety per cent of the resultant malignancies are chondrosarcomas. Malignant transformation before the age of 20 years is exceptional. Plain radiology is routinely used for monitoring of patients with MHE. Other modalities exist to assess for cartilage cap thickness, a much-debated criterion of malignant change. Pathology is essential for confirmation of malignant transformation as well as to exclude high grade lesions. Treatment is wide local excision (WLE) with limb-sparing surgery and long-term follow-up to detect for local recurrences. CONCLUSION: The malignant transformation of osteochondromas occurs more frequently in individuals with MHE and may even arise in the paediatric population. In the presence of suspicious clinical or radiological features, en-bloc surgical resection and histopathological correlation is mandatory to make the diagnosis. We encourage a multidisciplinary team approach with collaboration between the orthopaedic surgeon, radiologist and pathologist Level of evidence: Level 5 Keywords: multiple hereditary exostosis (MHE), chondrosarcoma, osteochondroma, malignant transformation
背景:多发性遗传性外生骨病(MHE)是一种罕见的常染色体显性遗传病,易导致多发性骨软骨瘤的发生。恶性转化是骨软骨瘤的罕见并发症,在儿科人群中尤其罕见。方法:在审查医院档案、放射学和病理之前,我们获得了知情同意和伦理批准,并进行了有针对性的文献检索。结果:一名11岁男性MHE患者,右腿新发疼痛,并伴有无法负重。x线平片和磁共振成像(MRI)显示与恶性转化相符的特征。该患儿接受了腓骨近端Malawer 1切除术,无并发症。病理证实由骨软骨瘤引起的1级继发性外周软骨肉瘤(CS)。在一些专科三级中心,MHE的恶性转化率高达36.3%。90%的恶性肿瘤是软骨肉瘤。20岁以前的恶性转化是罕见的。常规影像学检查用于MHE患者的监测。评估软骨帽厚度的其他方式存在,这是一个备受争议的恶性变化标准。病理是必要的恶性转化的确认,并排除高级别病变。治疗是广泛的局部切除(WLE)与肢体保留手术和长期随访,以发现局部复发。结论:骨软骨瘤的恶性转化在MHE患者中更常见,甚至可能出现在儿科人群中。在存在可疑的临床或放射学特征时,必须进行整体手术切除和组织病理学相关才能做出诊断。我们鼓励骨科医生、放射科医生和病理学家开展多学科合作。证据等级:5级。关键词:多发性遗传性外生性增生(MHE)、软骨肉瘤、骨软骨瘤、恶性转化
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引用次数: 0
Correlation of the squat-and-smile test against other patient-reported outcome scores in knee pathology 膝关节病理学中深蹲和微笑测试与其他患者报告的结果评分的相关性
Q4 Medicine Pub Date : 2021-08-31 DOI: 10.17159/2309-8309/2021/v20n3a4
J. Roux, R. Dey, A. Deichl, Oscar Torney, M. Laubscher, S. Graham, M. Held
ABSTRACT BACKGROUND: The use of patient-reported outcome measures (PROMs) for knee pathology may be affected by socioeconomic factors, language barriers and time constraints in busy outpatient clinics. The squat-and-smile test (SST) is an example of such a test that has previously been validated for femur fractures. The aim of this study was to validate the SST against other PROMs in patients with knee pathology METHODS: Patients presenting to a subspecialist knee clinic in a large hospital in sub-Saharan Africa were approached to participate. They were asked to squat and the depth of the squat as well as the need to support themselves were classified into four categories. To describe their pain, participants also selected one of three smiley faces (unhappy, neutral, smiling). These test scores were correlated to the patient's Knee injury and Osteoarthritis Outcome Score (KOOS), Tegner Lysholm score and EQ-5D scores RESULTS: Seventy patients (median age 53.4 years) were included. The squat depth correlated moderately with the KOOS score (r=0.56) and poorly with the EQ-5D and Lysholm scores (r=0.46; r=0.43). The need for squat support had poor correlations with the KOOS, EQ-5D and Lysholm scores (r=0.29; r=0.31; r=0.31), as did the smiley face component (r=0.40; r=0.32; r=0.30 CONCLUSION: For patients with knee pathology, the squat depth correlates moderately with other PROMs. It could therefore be used in settings for which conventional PROMs have limited application. Support needed to squat, and a visual analogue scale of smiley faces, had poor correlation when compared to other knee PROMs and should not be used for the assessment of knee pathology Level of evidence: Level 4 Keywords: squat and smile, KOOS, PROM, smiley faces, outcome score
摘要背景:在繁忙的门诊诊所,使用患者报告的结果测量(PROM)进行膝关节病理检查可能受到社会经济因素、语言障碍和时间限制的影响。深蹲微笑测试(SST)就是这样一个测试的例子,该测试之前已被验证用于股骨骨折。本研究的目的是验证SST与其他PROM在膝关节病理患者中的作用。方法:邀请撒哈拉以南非洲一家大型医院的膝关节亚专科诊所就诊的患者参与。他们被要求蹲下,蹲下的深度以及支撑自己的需要被分为四类。为了描述他们的痛苦,参与者还从三个笑脸中选择了一个(不开心、中性、微笑)。这些测试分数与患者的膝关节损伤和骨关节炎结果分数(KOOS)、Tegner-Lysholm分数和EQ-5D分数相关。结果:包括70名患者(中位年龄53.4岁)。深蹲深度与KOOS评分相关性中等(r=0.56),与EQ-5D和Lysholm评分相关性较差(r=0.46;r=0.43)。深蹲支撑需求与KOOS、EQ-5D、Lysholm得分相关性较差(r=0.29;r=0.31;r=0.31),笑脸组件也是如此(r=0.40;r=0.32;r=0.30结论:对于膝关节病变患者,深蹲深度与其他PROM适度相关。因此,它可以用于传统PROM应用有限的环境。与其他膝关节PROM相比,深蹲所需的支持和笑脸的视觉模拟量表相关性较差,不应用于评估膝关节路径logy证据水平:4级关键词:蹲着微笑、KOOS、PROM、笑脸、结果得分
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引用次数: 0
Positive patient experience of wide awake local anaesthesia no tourniquet (WALANT) hand surgery in the government setting: a prospective descriptive study 政府环境下广泛清醒局部麻醉无止血带(WALANT)手部手术的积极患者体验:一项前瞻性描述性研究
Q4 Medicine Pub Date : 2021-08-31 DOI: 10.17159/2309-8309/2021/v20n3a1
Jaco J. Naude, O. Koch, L. Schmidt, T. Roux
ABSTRACT BACKGROUND: The purpose of this study was to establish a subjective patient experience with wide awake local anaesthesia no tourniquet (WALANT) procedures performed in the institution from May 2019 to March 2020. WALANT surgery was initiated to improve standard operating procedure and to decrease theatre burden METHODS: This prospective, descriptive study included 100 patients with a mean age of 59 years who required either a carpal tunnel or trigger finger release. The patients' pain experience was documented on the visual analogue scale (VAS) for the local anaesthetic injection and the surgical procedure. Overall experience was assessed on the patient's preference to have the procedure performed by the WALANT method or the conventional method RESULTS: One hundred patients were included, of which 67 had medical comorbidities. The mean VAS score was 1.5 (SD±1.6) with pain on injection. The mean VAS pain score during the surgical procedure was 0.2 (SD±0.7). One hundred per cent of patients (100/100) felt they would do the WALANT outpatient procedure again instead of admission to hospital and surgery in the theatre. Two complications occurred related to wound care problems, and were successfully managed. None of the patients required reoperations for incomplete release of the carpal tunnel or trigger finger surgery CONCLUSION: The results of this study suggest that minor hand surgery using the WALANT protocol can be performed effectively and with high patient satisfaction rates in the orthopaedic outpatient clinic, and is a useful tool in the skillset of a hand surgeon Level of evidence: Level 4 Keywords: WALANT, hand surgery, trigger finger, carpal tunnel release
摘要背景:本研究的目的是建立2019年5月至2020年3月在该机构进行的全清醒局部麻醉无止血带(WALANT)手术的主观患者体验。WALANT手术旨在改善标准手术程序并减轻手术室负担。方法:这项前瞻性描述性研究包括100名平均年龄59岁的患者,他们需要腕管或扳机指松解术。患者的疼痛体验记录在局部麻醉注射和手术过程的视觉模拟量表(VAS)上。根据患者偏好采用WALANT方法或传统方法进行手术的总体经验进行评估。结果:包括100名患者,其中67名患者患有医疗合并症。注射时疼痛的平均VAS评分为1.5(SD±1.6)。手术过程中的平均VAS疼痛评分为0.2(SD±0.7)。100%的患者(100/100)认为他们会再次进行WALANT门诊手术,而不是入院和在手术室进行手术。发生了两起与伤口护理问题有关的并发症,并得到了成功处理。没有一名患者因腕管不完全松解或扳机指手术而需要再次手术。结论:本研究结果表明,在骨科门诊,使用WALANT方案的小型手部手术可以有效进行,患者满意度高,是手外科医生技能中的一个有用工具证据级别:4级关键词:WALANT,手部手术,扳机指,腕管松解术
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引用次数: 3
Antibiotic resistance - Netflix, HAL 9000 and the $100 billion question 抗生素耐药性-Netflix、HAL 9000和1000亿美元的问题
Q4 Medicine Pub Date : 2021-08-31 DOI: 10.17159/2309-8309/2021/v20n3a0
L. Marais
With Yuval Noah Harari’s ‘I told you so’ still ringing in our ears and the battlefield still ablaze, one cannot help but wonder what the next microorganism assault on humankind is going to involve.1 While we are still fully engaged on our main front, another old enemy is gathering strength on our flanks. Bacterial resistance has been described as the single most important threat to public health in the  21st century.2 The United Nations interagency group on bacterial resistance estimates that drug-resistant disease could rise from a current figure of around 700 000 deaths per annum to around 10 million a year by 2050, if we don’t act.3 The six most common bacterial pathogens in orthopaedics are currently all on the CDC (Centers for Disease Control and Prevention) ‘Urgent’ or ‘Serious’ threat list.4 A meta-analysis estimated that 39% to 51% of surgical site infection in the USA was caused by bacteria that are resistant to  the standard prophylactic antibiotics.5 Our primary tool against resistance is antibiotic stewardship programmes. But wil it solve the problem?
尤瓦尔·诺亚·赫拉利(Yuval Noah Harari)的那句“我早告诉过你”还在耳边回响,战场还在熊熊燃烧,人们不禁想知道,下一次微生物对人类的攻击将涉及什么当我们仍在主战线上全力作战时,另一个宿敌正在我们的侧翼集结兵力。细菌耐药性被认为是21世纪对公众健康最重要的威胁联合国细菌耐药性机构间小组估计,如果我们不采取行动,到2050年,耐药性疾病的死亡人数可能会从目前的每年约70万人上升到每年约1000万人骨科中最常见的六种细菌病原体目前都在疾病控制和预防中心(CDC)的“紧急”或“严重”威胁清单上一项荟萃分析估计,在美国39%至51%的手术部位感染是由对标准预防性抗生素耐药的细菌引起的我们对付耐药性的主要工具是抗生素管理规划。但这能解决问题吗?
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SA Orthopaedic Journal
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