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Internal Mammary Artery-saphenous Vein Y Anastomosis in Coronary Artery Bypass Grafting - Is there a Possibility of Coronary Steal? 冠状动脉旁路移植术中的乳内动脉-隐静脉 Y 型吻合术--是否存在冠状动脉盗血的可能性?
IF 0.5 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-01-01 Epub Date: 2024-04-12 DOI: 10.4103/heartviews.heartviews_38_23
Sathish Kumar, Pratik Pandey

Recent advances in coronary revascularization include total arterial grafting, however, in a few cases, harvesting the right internal thoracic artery (RITA) is not possible due to various reasons. In such cases, where the aorta is also calcified, few surgeons perform Y anastomosis configuration with the left internal thoracic artery(LITA) and saphenous vein which can have disastrous complications. Our patient is a 65-year-old man who was diagnosed with multivessel coronary disease and presented with a coronary steal during coronary artery bypass grafting surgery. The RITA was not harvested due to osteoporosis sternum. LITA-saphenous vein Y anastomosis configuration was done as the aorta was calcified. The anastomosis was done between the LITA to the left anterior descending (LAD) artery and the Y arm saphenous vein was anastomosed to an obtuse marginal (OM)branch. He developed coronary steal following anastomosis of the Y graft to the OM branch. The patient had ischemic changes inside the operation theatre in LAD territory, hence grafts were revised following which the patient became stable. There is a high possibility of a coronary steal when the caliber of the Y arm does not match with the LITA. LITA-saphenous vein Y anastomosis can cause more complications as the saphenous vein is much bigger in caliber compared to the LITA.

冠状动脉血运重建的最新进展包括全动脉移植,但在少数情况下,由于各种原因无法采集右胸内动脉(RITA)。在这种情况下,如果主动脉也已钙化,少数外科医生会用左胸内动脉(LITA)和隐静脉进行Y吻合配置,这可能会产生灾难性的并发症。我们的患者是一名 65 岁的男性,他被诊断患有多支血管冠状动脉疾病,并在冠状动脉旁路移植手术中出现冠状动脉盗血。由于胸骨骨质疏松,他没有采集到 RITA。由于主动脉已经钙化,因此采用了 LITA 与隐静脉 Y 型吻合术。LITA 与左前降支(LAD)动脉之间进行了吻合,Y 型臂隐静脉与钝缘 (OM) 支进行了吻合。在 Y 型移植物与 OM 支吻合后,他出现了冠状动脉盗血。患者在手术室内出现了左上动脉血管缺血性病变,因此对移植物进行了修补,随后患者病情稳定。当 Y 臂的口径与 LITA 不匹配时,很有可能发生冠状动脉盗血。LITA 与隐静脉 Y 型吻合术可能会引起更多并发症,因为隐静脉的口径比 LITA 大得多。
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引用次数: 0
The Results of Urgent and Emergent Transcatheter Mitral Valve Repair (MitraClip®): A Comparison with Standard Elective Repair. 紧急和急诊经导管二尖瓣修复术(MitraClip®)的结果:与标准择期修复术的比较。
IF 0.5 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-01-01 Epub Date: 2024-04-12 DOI: 10.4103/heartviews.heartviews_88_23
Mohammed Al-Tawil, Jesvin T Sunny, Christopher J Goulden, Tahiyyah Akhteruzzaman, Basel F Alqeeq, Amer Harky

Background: Mitral regurgitation (MR) is the most common valvular disease worldwide. MR has been managed surgically, with either a mitral valve replacement or repair. Percutaneous transcatheter mitral valve repair (TMVr) with MitraClip® insertion has gained wide popularity and success over medical and surgical therapy for MR. Some patients with acute MR or decompensated heart failure could benefit from urgent TMVr. This meta-analysis aims to compare clinical outcomes of urgent versus elective TMVr.

Methods: We performed a study-level meta-analysis to compare the clinical outcomes of urgent versus elective TMVr using the MitraClip system. The primary endpoint outcome was all-cause mortality. Additional outcomes included procedural success, postoperative acute kidney injury (AKI), stroke, and length of in-hospital stay.

Results: Overall, 30-day mortality was significantly higher in the urgent group (odds ratio [OR]: 2.74; 95% confidence interval [CI] [2.17, 3.48]; P < 0.00001; I² =0%). However, subgroup analysis of matched cohorts showed no significant difference between both groups (OR: 1.80; 95% CI [0.94, 3.46]; P = 0.08; I² =0%). One-year mortality was similar between both groups (and: 1.67; 95% CI [0.96, 2.90]; P = 0.07; I² =0%). Procedural success was similar between both groups (89.4% vs. 89.8%; P = 0.43). Postoperative AKI was significantly higher in the urgent group (OR: 4.12; 95% CI [2.87, 5.91]; P < 0.00001; I² =0%).

Conclusion: Urgent TMVr should be indicated in select populations as it is considered therapeutic with acceptable outcomes therein.

背景:二尖瓣反流(MR)是全球最常见的瓣膜疾病。二尖瓣反流一直采用手术治疗,即二尖瓣置换术或修复术。与内科和外科治疗相比,插入 MitraClip® 的经皮经导管二尖瓣修复术(TMVr)已广受欢迎并取得成功。一些急性二尖瓣狭窄或失代偿性心力衰竭患者可从紧急的 TMVr 中获益。本荟萃分析旨在比较紧急 TMVr 与择期 TMVr 的临床疗效:我们进行了一项研究层面的荟萃分析,比较了使用 MitraClip 系统的紧急 TMVr 与择期 TMVr 的临床疗效。主要终点结果是全因死亡率。其他结果包括手术成功率、术后急性肾损伤(AKI)、中风和住院时间:总体而言,急诊组的 30 天死亡率明显更高(几率比 [OR]:2.74;95% 置信区间 [CI] [2.17,3.48];P < 0.00001;I² =0%)。然而,对匹配队列进行的亚组分析显示,两组之间没有明显差异(OR:1.80;95% CI [0.94,3.46];P = 0.08;I² =0%)。两组的一年死亡率相似(和:1.67;95% CI [0.96,2.90];P = 0.07;I² =0%)。两组的手术成功率相似(89.4% vs. 89.8%;P = 0.43)。急诊组术后AKI明显更高(OR:4.12;95% CI [2.87,5.91];P < 0.00001;I² =0%):结论:紧急 TMVr 应适用于特定人群,因为它被认为具有治疗作用,且结果可接受。
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引用次数: 0
EDITOR's GOODBYE. EDITOR'S GOODBYE.
IF 0.5 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-01-01 Epub Date: 2024-04-12 DOI: 10.4103/heartviews.heartviews_30_24
Rachel Hajar
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引用次数: 0
K-clip™, a Novel Transcatheter Treatment in Patients with Severely Tricuspid Regurgitation. K-clip™ 是一种用于严重三尖瓣反流患者的新型经导管疗法。
IF 0.5 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-01-01 Epub Date: 2024-04-12 DOI: 10.4103/heartviews.heartviews_89_23
Jiandong Ding, Rongfeng Xu, Xiaoli Zhang, Genshan Ma

Patients who suffer from severe tricuspid regurgitation (TR) and who are at high surgical risk have no standard care therapy. Therefore, minimally invasive and safer methods are sought. K-clip™, the first ultrasound-positioned interventional tricuspid annuloplasty instrument intended for percutaneous transcatheter repair. We report a patient with severe functional TR and high surgical risk who underwent K-clip™ tricuspid annuloplasty under echocardiography and fluoroscopy guidance.

患有严重三尖瓣反流(TR)且手术风险高的患者没有标准的治疗方法。因此,人们寻求微创和更安全的方法。K-clip™是首个用于经皮导管修复的超声定位介入三尖瓣瓣环成形器。我们报告了一名患有严重功能性 TR 且手术风险较高的患者,她在超声心动图和透视引导下接受了 K-clip™ 三尖瓣瓣环成形术。
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引用次数: 0
Study of the Histopathological Changes in the Heart in Postmortem/Autopsy Cases in Tertiary Care Center. 研究三级医疗中心尸检/活体解剖病例中心脏的组织病理学变化。
IF 0.5 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-01-01 Epub Date: 2024-04-12 DOI: 10.4103/heartviews.heartviews_45_23
Shivaji Dadarao Birare, Dinesh Vishwanath Swami, Sarika Sanjay Gaikwad, Roshani Rajesh Malpani

Context: There has been a significant increase in global cardiac-related fatalities, particularly over the last five decades. In India, cardiovascular diseases have emerged as a prevalent condition. Moreover, the incidence of sudden cardiac death has shown a steady rise worldwide.

Aims: The aim of this study was to research how frequently cardiac disease was found during postmortem/autopsy cases and how it affects sudden death.

Materials and methods: The research was conducted at the Department of Pathology, SRTR, GMC, Ambajogai, India. One hundred and eighty cardiac specimens were examined from October 2019 to October 2021. Formalin-fixed heart specimens had multiple sections cut out of them at 4-5 mm intervals. The tissues underwent preparation, followed by sectioning into 4 μm thickness using paraffin. The standard staining method of hematoxylin and eosin was used to stain the samples. Different cardiac histomorphological alterations were assessed.

Results: The study included 180 autopsy cases. The highest numbers of cases were observed in the age group of 31-40 years (20.2%). Triple-vessel involvement was seen in the majority of 61.5% of cases, out of 180 cases, 52.7% of cases were of hypertrophy.

Conclusions: The research highlights the prevalence of cardiovascular diseases, particularly atherosclerosis and hypertrophy. Notably, sudden death cases showed a distinct distribution across the study years, with males being predominantly affected. This underscores the urgent need for preventive measures and interventions to prevalent cardiovascular conditions effectively.

背景:全球与心脏相关的死亡人数大幅增加,尤其是在过去的五十年里。在印度,心血管疾病已成为一种流行病。此外,心脏性猝死的发病率在全球范围内呈稳步上升趋势。研究目的:本研究旨在研究在尸检/活体解剖病例中发现心脏疾病的频率及其对猝死的影响:研究在印度Ambajogai的GMC SRTR病理学系进行。从 2019 年 10 月到 2021 年 10 月,共检查了 180 份心脏标本。福尔马林固定的心脏标本以 4-5 毫米的间距切取多个切片。组织经过制备,然后用石蜡切成 4 μm 厚的切片。样本采用苏木精和伊红标准染色法进行染色。对不同的心脏组织形态学改变进行评估:研究包括 180 例尸检病例。31-40岁年龄组的病例数最多(20.2%)。在 180 个病例中,52.7% 的病例为肥厚型,61.5% 的病例可见三血管受累:这项研究强调了心血管疾病,尤其是动脉粥样硬化和肥厚的发病率。值得注意的是,猝死病例在不同研究年份有明显的分布,男性患者居多。这突出表明,迫切需要采取预防措施和干预措施来有效预防心血管疾病。
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引用次数: 0
Two-dimensional speckle tracking strain echocardiography in a case of acute myopericarditis due to COVID-19 virus 二维斑点追踪应变超声心动图在COVID-19型急性心包炎中的应用
Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-01-01 DOI: 10.4103/heartviews.heartviews_68_23
AjitkumarKrishna Jadhav
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引用次数: 0
Renal function improvement after aortic valve replacement in a patient with chronic kidney disease – A case report 慢性肾病患者主动脉瓣置换术后肾功能改善1例报告
Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-01-01 DOI: 10.4103/heartviews.heartviews_37_23
Gauri Parvathy, Sathish Kumar, AzharSalimahmed Sayyed, Kiranmoy Roy
Inadequate peripheral perfusion due to cardiac diseases can worsen renal function in patients with chronic kidney disease (CKD). Due to the nature of the simultaneous cardiac and renal disease, it is often difficult to determine which is the primary cause, and hence many surgeons hesitate to operate on patients with end-stage kidney disease. However, when the primary cause is cardiac related, renal function can improve after successful cardiac surgery. Here, we describe a 55-year-old female patient with CKD Stage 5 who was on maintenance hemodialysis with severe aortic stenosis (AS) and underwent surgical aortic valve replacement and recovered from dialysis-dependent kidney disease. Drastic improvement in renal function after cardiac surgery can occur even in patients with CKD due to improved renal perfusion, especially in cases of AS. Therefore, diagnosing the primary cause of renal dysfunction is essential.
心脏疾病引起的外周灌注不足可使慢性肾脏疾病(CKD)患者的肾功能恶化。由于心脏和肾脏同时发生疾病的性质,通常很难确定哪一个是主要原因,因此许多外科医生对终末期肾脏疾病患者的手术犹豫不决。然而,当主要原因与心脏有关时,心脏手术成功后肾功能可以改善。在这里,我们描述了一位55岁的女性CKD 5期患者,她患有严重的主动脉狭窄(AS),接受维持性血液透析,并接受了手术主动脉瓣置换术,并从透析依赖性肾脏疾病中恢复过来。即使是CKD患者,由于肾脏灌注改善,心脏手术后肾功能也会出现显著改善,尤其是AS患者。因此,诊断肾功能不全的主要原因是必要的。
{"title":"Renal function improvement after aortic valve replacement in a patient with chronic kidney disease – A case report","authors":"Gauri Parvathy, Sathish Kumar, AzharSalimahmed Sayyed, Kiranmoy Roy","doi":"10.4103/heartviews.heartviews_37_23","DOIUrl":"https://doi.org/10.4103/heartviews.heartviews_37_23","url":null,"abstract":"Inadequate peripheral perfusion due to cardiac diseases can worsen renal function in patients with chronic kidney disease (CKD). Due to the nature of the simultaneous cardiac and renal disease, it is often difficult to determine which is the primary cause, and hence many surgeons hesitate to operate on patients with end-stage kidney disease. However, when the primary cause is cardiac related, renal function can improve after successful cardiac surgery. Here, we describe a 55-year-old female patient with CKD Stage 5 who was on maintenance hemodialysis with severe aortic stenosis (AS) and underwent surgical aortic valve replacement and recovered from dialysis-dependent kidney disease. Drastic improvement in renal function after cardiac surgery can occur even in patients with CKD due to improved renal perfusion, especially in cases of AS. Therefore, diagnosing the primary cause of renal dysfunction is essential.","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135445628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful bail out of rotablator driveshaft fracture due to severe calcified lesion and proximal tortuosity 由于严重钙化病变和近端扭曲导致的旋转驱动轴骨折成功抢救
Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-01-01 DOI: 10.4103/heartviews.heartviews_28_23
Hiroki Uehara, Masaki Okuyama, Yutaro Oe, Takaki Yoshimura, Takahiro Gunji
A 59-year-old male dialysis patient with a history of coronary artery bypass graft surgery underwent percutaneous coronary intervention of a right coronary artery with a severely calcified lesion. While debulking calcification using a Rotablator, the driveshaft was suddenly fractured. We attempted to move a child-in-mother catheter closer and across a second floppy wire and we dilated a 2.0-mm noncompliant balloon to trap the driveshaft, which we then removed, and restarted the intervention.
59岁男性透析患者,有冠状动脉搭桥手术史,经皮冠状动脉介入治疗右冠状动脉严重钙化病变。当使用旋转器去除钙化时,传动轴突然断裂。我们试图通过第二根软线将母子导管移动得更近一些,并扩大一个2.0 mm的不顺应球囊来包裹传动轴,然后将其取出,重新开始干预。
{"title":"Successful bail out of rotablator driveshaft fracture due to severe calcified lesion and proximal tortuosity","authors":"Hiroki Uehara, Masaki Okuyama, Yutaro Oe, Takaki Yoshimura, Takahiro Gunji","doi":"10.4103/heartviews.heartviews_28_23","DOIUrl":"https://doi.org/10.4103/heartviews.heartviews_28_23","url":null,"abstract":"A 59-year-old male dialysis patient with a history of coronary artery bypass graft surgery underwent percutaneous coronary intervention of a right coronary artery with a severely calcified lesion. While debulking calcification using a Rotablator, the driveshaft was suddenly fractured. We attempted to move a child-in-mother catheter closer and across a second floppy wire and we dilated a 2.0-mm noncompliant balloon to trap the driveshaft, which we then removed, and restarted the intervention.","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135445625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusual hemodynamic pressure trace mimicking aortic stenosis: A decepti “Con” 一个不寻常的血流动力学压力痕迹模拟主动脉狭窄:一个欺骗“骗局”
Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-01-01 DOI: 10.4103/heartviews.heartviews_18_23
Aditya Kapoor, AnkitKumar Sahu, Kamlesh Raut, Sudeep Kumar
We report an abnormal hemodynamic pressure tracing taken during pullback from the left ventricle. This report emphasizes the careful observation of hemodynamic tracing relative to continuous electrocardiographic monitoring for identifying potentially pathological vascular phenomena that may have detrimental outcomes on the clinical management of the underlying condition.
我们报告一个异常的血流动力学压力追踪从左心室拉回。本报告强调,相对于连续的心电图监测,仔细观察血流动力学追踪可以识别潜在的病态性血管现象,这些现象可能对潜在疾病的临床治疗产生不利影响。
{"title":"An unusual hemodynamic pressure trace mimicking aortic stenosis: A decepti “Con”","authors":"Aditya Kapoor, AnkitKumar Sahu, Kamlesh Raut, Sudeep Kumar","doi":"10.4103/heartviews.heartviews_18_23","DOIUrl":"https://doi.org/10.4103/heartviews.heartviews_18_23","url":null,"abstract":"We report an abnormal hemodynamic pressure tracing taken during pullback from the left ventricle. This report emphasizes the careful observation of hemodynamic tracing relative to continuous electrocardiographic monitoring for identifying potentially pathological vascular phenomena that may have detrimental outcomes on the clinical management of the underlying condition.","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134982099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new era of clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 gene editing technology in cardiovascular diseases: Opportunities, challenges, and perspectives 聚类规律间隔短回文重复序列/ crispr相关蛋白9基因编辑技术在心血管疾病中的新时代:机遇、挑战和前景
Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-01-01 DOI: 10.4103/heartviews.heartviews_49_23
Kumar Rahul, SushilKumar Singh, Sarvesh Kumar, Vivek Tewarson, MohammadZeeshan Hakim, Karan Kaushik, Satish Kumar, Bhupendra Kumar
Cardiovascular diseases (CVDs) remain major causes of global mortality in the world. Genetic approaches have succeeded in the discovery of the molecular basis of an increasing number of cardiac diseases. Genome-editing strategies are one of the most effective methods for assisting therapeutic approaches. Potential therapeutic methods of correcting disease-causing mutations or of knocking out specific genes as approaches for the prevention of CVDs have gained substantial attention using genome-editing techniques. Recently, the clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) system has become the most widely used genome-editing technology in molecular biology due to its benefits such as simple design, high efficiency, good repeatability, short cycle, and cost-effectiveness. In the present review, we discuss the possibilities of applying the CRISPR/Cas9 genome-editing tool in the CVDs.
心血管疾病(cvd)仍然是全球死亡的主要原因。遗传方法已经成功地发现了越来越多心脏疾病的分子基础。基因组编辑策略是辅助治疗方法的最有效方法之一。利用基因组编辑技术纠正致病突变或敲除特定基因作为预防心血管疾病的方法的潜在治疗方法已经获得了大量关注。近年来,聚集规律间隔短回文重复序列/CRISPR-associated protein 9 (CRISPR/Cas9)系统以其设计简单、效率高、可重复性好、周期短、成本效益高等优点,成为分子生物学中应用最广泛的基因组编辑技术。在这篇综述中,我们讨论了CRISPR/Cas9基因组编辑工具在心血管疾病中应用的可能性。
{"title":"A new era of clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 gene editing technology in cardiovascular diseases: Opportunities, challenges, and perspectives","authors":"Kumar Rahul, SushilKumar Singh, Sarvesh Kumar, Vivek Tewarson, MohammadZeeshan Hakim, Karan Kaushik, Satish Kumar, Bhupendra Kumar","doi":"10.4103/heartviews.heartviews_49_23","DOIUrl":"https://doi.org/10.4103/heartviews.heartviews_49_23","url":null,"abstract":"Cardiovascular diseases (CVDs) remain major causes of global mortality in the world. Genetic approaches have succeeded in the discovery of the molecular basis of an increasing number of cardiac diseases. Genome-editing strategies are one of the most effective methods for assisting therapeutic approaches. Potential therapeutic methods of correcting disease-causing mutations or of knocking out specific genes as approaches for the prevention of CVDs have gained substantial attention using genome-editing techniques. Recently, the clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) system has become the most widely used genome-editing technology in molecular biology due to its benefits such as simple design, high efficiency, good repeatability, short cycle, and cost-effectiveness. In the present review, we discuss the possibilities of applying the CRISPR/Cas9 genome-editing tool in the CVDs.","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134982104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Heart Views
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