M. Montemezzo, A. AlTurki, Marcos Jakolinski, J. C. Jorge
with the syncopal episode. The patient has no other known comorbidities and no significant family history. A transthoracic echocardiogram revealed a normal left ventricular ejection fraction (68%), normal heart valves, and normal right ventricular size and function. The electrolytes and thyroid function were normal. In addition, an exercise electrocardiographic stress test was normal. She was therefore referred for a pacemaker implantation, and given her ongoing pregnancy, an alternative technique was applied. The patient was brought to the electrophysiology laboratory, and prior to commencing the procedure, a fetal heartbeat monitor was installed, and the entire procedure was followed by an obstetrician. The patient was sedated, using propofol, and both the right groin as well as the left pectoral region were ??? and draped using alcoholic chlorhexidine. Under local anesthesia, with 2% lidocaine 10cc, the right femoral vein was
{"title":"Pacemaker Implantation without Fluoroscopy and Guided by Anatomical Mapping","authors":"M. Montemezzo, A. AlTurki, Marcos Jakolinski, J. C. Jorge","doi":"10.36660/ijcs.20210005","DOIUrl":"https://doi.org/10.36660/ijcs.20210005","url":null,"abstract":"with the syncopal episode. The patient has no other known comorbidities and no significant family history. A transthoracic echocardiogram revealed a normal left ventricular ejection fraction (68%), normal heart valves, and normal right ventricular size and function. The electrolytes and thyroid function were normal. In addition, an exercise electrocardiographic stress test was normal. She was therefore referred for a pacemaker implantation, and given her ongoing pregnancy, an alternative technique was applied. The patient was brought to the electrophysiology laboratory, and prior to commencing the procedure, a fetal heartbeat monitor was installed, and the entire procedure was followed by an obstetrician. The patient was sedated, using propofol, and both the right groin as well as the left pectoral region were ??? and draped using alcoholic chlorhexidine. Under local anesthesia, with 2% lidocaine 10cc, the right femoral vein was","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85427933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Luíza Machado Nogueira, Ana Luísa dos Santos Maciel, Amanda Campos Querubino, Roberta Teixeira Prado, Jussara Regina Martins
Background: Therapeutic hypothermia is used in adults and neonates after cardiac arrest, but its efficiency in children under 18 years old is still uncertain. Objective: To evaluate the effectiveness and risks of therapeutic hypothermia after cardiac arrest in children under 18 years of age through a systematic review. Methods: A systematic review was performed in January 2022 in the MEDLINE, SciELO, Cochrane, and LILACS databases. Inclusion criteria: randomized controlled trials (RCTs) performed in humans. Articles from other typologies, published more than 10 years ago, or with volunteers over 18 years old were excluded. Results: Four studies were identified, of which 3 were analyzed; all of them were of moderate quality according to the Jadad Scale and the Cochrane Collaboration tool. The studies indicated that lowering the temperature did not improve data on mortality and adverse events. Two studies did not identify statistically significant differences (p > 0.05) considering hypothermia in relation to normothermia in terms of survival, safety, and global neurobehavioral and cognitive function. The other study did not show improved serum biomarker concentrations. Conclusions: The results found in this review do not support the use of therapeutic hypothermia after pediatric cardiac arrest, as this intervention did not provide any apparent benefits in terms of safety, adverse events, survival, and neurological impact. We recommend the conduction of new RCTs using the measurement of serum biomarkers to better evaluate the effectiveness of the intervention.
{"title":"Efficacy and Risks of Therapeutic Hypothermia after Pediatric Cardiac Arrest: A Systematic Review","authors":"Anna Luíza Machado Nogueira, Ana Luísa dos Santos Maciel, Amanda Campos Querubino, Roberta Teixeira Prado, Jussara Regina Martins","doi":"10.36660/ijcs.20210246","DOIUrl":"https://doi.org/10.36660/ijcs.20210246","url":null,"abstract":"Background: Therapeutic hypothermia is used in adults and neonates after cardiac arrest, but its efficiency in children under 18 years old is still uncertain. Objective: To evaluate the effectiveness and risks of therapeutic hypothermia after cardiac arrest in children under 18 years of age through a systematic review. Methods: A systematic review was performed in January 2022 in the MEDLINE, SciELO, Cochrane, and LILACS databases. Inclusion criteria: randomized controlled trials (RCTs) performed in humans. Articles from other typologies, published more than 10 years ago, or with volunteers over 18 years old were excluded. Results: Four studies were identified, of which 3 were analyzed; all of them were of moderate quality according to the Jadad Scale and the Cochrane Collaboration tool. The studies indicated that lowering the temperature did not improve data on mortality and adverse events. Two studies did not identify statistically significant differences (p > 0.05) considering hypothermia in relation to normothermia in terms of survival, safety, and global neurobehavioral and cognitive function. The other study did not show improved serum biomarker concentrations. Conclusions: The results found in this review do not support the use of therapeutic hypothermia after pediatric cardiac arrest, as this intervention did not provide any apparent benefits in terms of safety, adverse events, survival, and neurological impact. We recommend the conduction of new RCTs using the measurement of serum biomarkers to better evaluate the effectiveness of the intervention.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80962675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Tonelli, Z. A. Meira, S. R. Castilho, A. F. M. Guimarães, T. Queiroz, A. Ferreira
,
，
{"title":"Abnormalities of Cardiac Situs and Heart Disease Diagnosed by Echocardiography in Patients with Biliary Atresia","authors":"H. Tonelli, Z. A. Meira, S. R. Castilho, A. F. M. Guimarães, T. Queiroz, A. Ferreira","doi":"10.36660/ijcs.20210207","DOIUrl":"https://doi.org/10.36660/ijcs.20210207","url":null,"abstract":",","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79208385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Flávia Gomes de Britto Neves, Rodrigo Pinheiro de Toledo Vianna, Marina Travassos Lopes
Background: Cardiovascular risk in adolescence is a public health problem that has grown along with the increase in soft drink consumption. Objective: To investigate the association between cardiovascular risk factors and daily consumption of soft drinks in Brazilian adolescents. Methods: We conducted a cross-sectional, national, school-based study of 36,956 Brazilian adolescents aged 12 to 17 years. Daily soft drink consumption was estimated using a 24-hour dietary recall. Cardiovascular risk was categorized as overweight, obesity, hypertension, hyperglycemia, and dyslipidemia. The survey command of Stata 14.0® was used to analyze data from a complex sample. The chi-square test was used to assess differences in soft drink consumption and other variables in the descriptive analysis. The odds ratio of cardiovascular risk factors and their respective 95% confidence intervals were estimated, considering sociodemographic and behavioral variables in the Mantel-Haenszel model. Statistical significance was set at p < 0.05. Results: Daily consumption of soft drinks was common among adolescents. A daily serving ≥ 450 mL was significantly associated with overweight and hypertension. Results associated with the consumption of regular soft drinks show the possibility of reverse causality. Consumption of diet soft drinks in adolescence should be considered a cardiovascular risk factor. Conclusion: Daily consumption of soft drinks can be understood as a relevant risk factor in the epidemiological scenario. Improper eating habits are multifactorial in nature and need to be better understood in the context of adolescent health and further explored in national surveys.
{"title":"Association between Cardiovascular Risk in Adolescents and Daily Consumption of Soft Drinks: a Brazilian National Study","authors":"Ana Flávia Gomes de Britto Neves, Rodrigo Pinheiro de Toledo Vianna, Marina Travassos Lopes","doi":"10.36660/ijcs.20200268","DOIUrl":"https://doi.org/10.36660/ijcs.20200268","url":null,"abstract":"Background: Cardiovascular risk in adolescence is a public health problem that has grown along with the increase in soft drink consumption. Objective: To investigate the association between cardiovascular risk factors and daily consumption of soft drinks in Brazilian adolescents. Methods: We conducted a cross-sectional, national, school-based study of 36,956 Brazilian adolescents aged 12 to 17 years. Daily soft drink consumption was estimated using a 24-hour dietary recall. Cardiovascular risk was categorized as overweight, obesity, hypertension, hyperglycemia, and dyslipidemia. The survey command of Stata 14.0® was used to analyze data from a complex sample. The chi-square test was used to assess differences in soft drink consumption and other variables in the descriptive analysis. The odds ratio of cardiovascular risk factors and their respective 95% confidence intervals were estimated, considering sociodemographic and behavioral variables in the Mantel-Haenszel model. Statistical significance was set at p < 0.05. Results: Daily consumption of soft drinks was common among adolescents. A daily serving ≥ 450 mL was significantly associated with overweight and hypertension. Results associated with the consumption of regular soft drinks show the possibility of reverse causality. Consumption of diet soft drinks in adolescence should be considered a cardiovascular risk factor. Conclusion: Daily consumption of soft drinks can be understood as a relevant risk factor in the epidemiological scenario. Improper eating habits are multifactorial in nature and need to be better understood in the context of adolescent health and further explored in national surveys.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81056646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luciana Gonçalves de Orange, M. Andrade, Cybelle Rolim de Lima, K. Dourado, Thayná Menezes Santos, M. M. Petribú, Priscilla Régia de Andrade Calaça, Silvia Alves Silva
To review scientific evidence on the effects of a gluten-free diet on body composition and improvement of clinical and biochemical parameters of metabolic syndrome. The Preferred Reporting Items for Systematic Reviews and Meta-Analyzes - PRISMA guidelines were followed. A literature search was performed in the PubMed, ScienceDirect, Trip Database, Bireme and Scielo databases, without language restriction, until March 2021. The terms “gluten-free diet”, “obesity”, “metabolic syndrome”, and “weight loss”, and Boolean operators (AND/OR) were used. The clinical hypothesis was structured according to the acronym PICOT. Randomized clinical trials with adult and elderly humans without a diagnosis of celiac disease, consuming a gluten-free diet, evaluating associations of the effects of this diet on weight loss and metabolic syndrome components were considered eligible. To assess the risk of bias, the RoB2 was used. A total of 3,198 articles were identified and, after the screening and evaluation of pre-defined eligibility criteria, four studies were included in the qualitative analysis. Weight loss was not associated with a gluten-free diet. However, individuals under a gluten-free diet had lower mean waist circumference, fat percentage (-2.3%) and serum triglyceride levels. The impact of a gluten-free diet on metabolic syndrome parameters is still controversial. In individuals without gluten sensitivity or celiac disease, the consumption of a gluten-free diet appears to provide no nutritional benefit. cholesterol <40mg/ dL). 1 These criteria are also adopted by the I Brazilian Guidelines on diagnosis and treatment of metabolic syndrome 2 and the American Heart Association. 3 The management of MS has been focused on attenuating modifiable risk factors, including overweight/obesity and changes of lifestyle (mainly diet), thereby contributing to the reduction of its incidence and complications. 4 Dietary strategies that have been used in the management of MS include the traditional Mediterranean diet (MD) characterized by a high intake of cereals, vegetables, and olive oil, a moderate intake of fish and alcohol, a low intake of dairy products, red meat, and sweets; 5,6 and the ketogenic diet, composed of 55-65% of fat, less than 20% of carbohydrates and 25-35% of proteins; the lactose-free diet, and the gluten-free diet (GFD). 7 Gluten is an insoluble protein complex, obtained during hydration of two cereal proteins, gliadin and glutenin. It is found in wheat, rye and barley and is source of several nutrients. 8 A GFD excludes foods containing
{"title":"Does a Gluten-free Diet Improve Metabolic Syndrome Parameters? A Systematic Review","authors":"Luciana Gonçalves de Orange, M. Andrade, Cybelle Rolim de Lima, K. Dourado, Thayná Menezes Santos, M. M. Petribú, Priscilla Régia de Andrade Calaça, Silvia Alves Silva","doi":"10.36660/ijcs.20200291","DOIUrl":"https://doi.org/10.36660/ijcs.20200291","url":null,"abstract":"To review scientific evidence on the effects of a gluten-free diet on body composition and improvement of clinical and biochemical parameters of metabolic syndrome. The Preferred Reporting Items for Systematic Reviews and Meta-Analyzes - PRISMA guidelines were followed. A literature search was performed in the PubMed, ScienceDirect, Trip Database, Bireme and Scielo databases, without language restriction, until March 2021. The terms “gluten-free diet”, “obesity”, “metabolic syndrome”, and “weight loss”, and Boolean operators (AND/OR) were used. The clinical hypothesis was structured according to the acronym PICOT. Randomized clinical trials with adult and elderly humans without a diagnosis of celiac disease, consuming a gluten-free diet, evaluating associations of the effects of this diet on weight loss and metabolic syndrome components were considered eligible. To assess the risk of bias, the RoB2 was used. A total of 3,198 articles were identified and, after the screening and evaluation of pre-defined eligibility criteria, four studies were included in the qualitative analysis. Weight loss was not associated with a gluten-free diet. However, individuals under a gluten-free diet had lower mean waist circumference, fat percentage (-2.3%) and serum triglyceride levels. The impact of a gluten-free diet on metabolic syndrome parameters is still controversial. In individuals without gluten sensitivity or celiac disease, the consumption of a gluten-free diet appears to provide no nutritional benefit. cholesterol <40mg/ dL). 1 These criteria are also adopted by the I Brazilian Guidelines on diagnosis and treatment of metabolic syndrome 2 and the American Heart Association. 3 The management of MS has been focused on attenuating modifiable risk factors, including overweight/obesity and changes of lifestyle (mainly diet), thereby contributing to the reduction of its incidence and complications. 4 Dietary strategies that have been used in the management of MS include the traditional Mediterranean diet (MD) characterized by a high intake of cereals, vegetables, and olive oil, a moderate intake of fish and alcohol, a low intake of dairy products, red meat, and sweets; 5,6 and the ketogenic diet, composed of 55-65% of fat, less than 20% of carbohydrates and 25-35% of proteins; the lactose-free diet, and the gluten-free diet (GFD). 7 Gluten is an insoluble protein complex, obtained during hydration of two cereal proteins, gliadin and glutenin. It is found in wheat, rye and barley and is source of several nutrients. 8 A GFD excludes foods containing","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"196 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79877526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christiane Rodrigues Alves, S. Chermont, Christiane Cigagna Wiefels Reis, E. Nascimento, M. Ribeiro, F. Ribeiro, E. Mesquita, C. Mesquita
Background: Cardiac resynchronization therapy (CRT) is an effective treatment for patients with heart failure. Objective: To evaluate the response of CRT in maximal inspiratory pressure (MIP), peak expiratory flow (PEF), and exercise tolerance as determined by the six-minute walk test (6MWT) in patients with HF. Methods: This study used the 6MWT and Manovacuometer to assess functional capacity in relation to activities of daily living, in which fatigue and dyspnea are common. Results: After six months of CRT, this study identified improvements in the 6MWT, p<0.05; MIP, p=0.01; and PEF, p=0.03. Conclusion: After CRT, this study showed a significant improvement in MIP, PEF, and exercise tolerance. However, further studies are warranted to demonstrate the relevance of these findings.
背景:心脏再同步化治疗(CRT)是治疗心力衰竭的有效方法。目的:评价CRT对HF患者最大吸气压(MIP)、呼气峰流量(PEF)和6分钟步行试验(6MWT)测定的运动耐量的影响。方法:本研究使用6MWT和压力计来评估与日常生活活动相关的功能能力，其中疲劳和呼吸困难是常见的。结果:CRT治疗6个月后，本研究发现6MWT改善，p<0.05;MIP, p = 0.01;PEF, p=0.03。结论:CRT后，本研究显示MIP、PEF和运动耐量有显著改善。然而，需要进一步的研究来证明这些发现的相关性。
{"title":"Effects of Cardiac Resynchronization Therapy on a Six-minute Walk Test, Maximal Inspiratory Pressure and Peak Expiratory Flow in Patients with Heart Failure: A Longitudinal Study","authors":"Christiane Rodrigues Alves, S. Chermont, Christiane Cigagna Wiefels Reis, E. Nascimento, M. Ribeiro, F. Ribeiro, E. Mesquita, C. Mesquita","doi":"10.36660/ijcs.20190158","DOIUrl":"https://doi.org/10.36660/ijcs.20190158","url":null,"abstract":"Background: Cardiac resynchronization therapy (CRT) is an effective treatment for patients with heart failure. Objective: To evaluate the response of CRT in maximal inspiratory pressure (MIP), peak expiratory flow (PEF), and exercise tolerance as determined by the six-minute walk test (6MWT) in patients with HF. Methods: This study used the 6MWT and Manovacuometer to assess functional capacity in relation to activities of daily living, in which fatigue and dyspnea are common. Results: After six months of CRT, this study identified improvements in the 6MWT, p<0.05; MIP, p=0.01; and PEF, p=0.03. Conclusion: After CRT, this study showed a significant improvement in MIP, PEF, and exercise tolerance. However, further studies are warranted to demonstrate the relevance of these findings.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"167 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76253591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Salazar, Cristhian Espinoza Romero, M. P. Lopes, C. E. Branco, J. Soares, A. Santis, R. Sampaio, F. Tarasoutchi
lactic dehydrogenase 297 U/ml, C-reactive protein 2.5 mg/L). A gallium-67 scintigraphy revealed increased concentration of the radiopharmaceutical in the cardiac area, with a diffuse pattern of uptake (Figure 1). Oral prednisone (1mg per kilogram per day) was started with good clinical response. MRI was conducted 72 hours after initiation of steroids, which showed LVEF of 44%, non-ischemic focal myocardial fibrosis with native T1 and extracellular volume, leading to the hypothesis of inflammatory cardiomyopathy (Figure 2). Seven days after prednisone, another TTE showed a significant improvement in LVEF, to 50%. Then, a fluorodeoxyglucose-(18F-FDG) PET-CT was performed, which confirmed myocardial uptake (Figure 3). Finally, the patient was discharged to finish corticosteroid therapy and referred for elective mitral and aortic valve replacement. is prevalent
{"title":"Cardiac Magnetic Resonance and Positron Emission Tomography in the Diagnosis and Follow-Up of Acute Rheumatic Fever - Case Report","authors":"D. Salazar, Cristhian Espinoza Romero, M. P. Lopes, C. E. Branco, J. Soares, A. Santis, R. Sampaio, F. Tarasoutchi","doi":"10.36660/ijcs.20210093","DOIUrl":"https://doi.org/10.36660/ijcs.20210093","url":null,"abstract":"lactic dehydrogenase 297 U/ml, C-reactive protein 2.5 mg/L). A gallium-67 scintigraphy revealed increased concentration of the radiopharmaceutical in the cardiac area, with a diffuse pattern of uptake (Figure 1). Oral prednisone (1mg per kilogram per day) was started with good clinical response. MRI was conducted 72 hours after initiation of steroids, which showed LVEF of 44%, non-ischemic focal myocardial fibrosis with native T1 and extracellular volume, leading to the hypothesis of inflammatory cardiomyopathy (Figure 2). Seven days after prednisone, another TTE showed a significant improvement in LVEF, to 50%. Then, a fluorodeoxyglucose-(18F-FDG) PET-CT was performed, which confirmed myocardial uptake (Figure 3). Finally, the patient was discharged to finish corticosteroid therapy and referred for elective mitral and aortic valve replacement. is prevalent","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90164714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Castro, João Giffoni da Silveira, A. Moreno, M. Orsini
ramp protocol on a treadmill (ATL, Inbrasport, Brazil). Oxygen uptake (VO 2 ), carbon dioxide (VCO 2 ), and ventilation (VE) were registered every ten seconds using a metabolic cart (Handymet, MDI, Brazil). Forced expiratory volume in one second (FEV1) was measured immediately before the exercise test and in several moments after peak exercise (immediately, 5 minutes, 10 minutes, and 15minutes) (Smart One, MIR, USA). A 12-lead electrocardiogram was continuously recorded (XCribe, Mortara, USA), and non-invasive blood pressure was measured each two-minutes The ventilatory threshold was identified by the combination of the following methods: 3 at the point of the first upward inflection of the ventilation vs. time curve, at the beginning of a consistent increase in the ventilatory equivalent for O2 (minute ventilation/ oxygen consumption) without a concomitant increase in the ventilatory equivalent for carbon dioxide (minute ventilation/carbon dioxide production), and at the beginning of an increase in expired oxygen fraction.
{"title":"Exercise-Induced Bronchoconstriction: A Frequent, but Neglected Cause of Chest Pain","authors":"R. Castro, João Giffoni da Silveira, A. Moreno, M. Orsini","doi":"10.36660/ijcs.20200376","DOIUrl":"https://doi.org/10.36660/ijcs.20200376","url":null,"abstract":"ramp protocol on a treadmill (ATL, Inbrasport, Brazil). Oxygen uptake (VO 2 ), carbon dioxide (VCO 2 ), and ventilation (VE) were registered every ten seconds using a metabolic cart (Handymet, MDI, Brazil). Forced expiratory volume in one second (FEV1) was measured immediately before the exercise test and in several moments after peak exercise (immediately, 5 minutes, 10 minutes, and 15minutes) (Smart One, MIR, USA). A 12-lead electrocardiogram was continuously recorded (XCribe, Mortara, USA), and non-invasive blood pressure was measured each two-minutes The ventilatory threshold was identified by the combination of the following methods: 3 at the point of the first upward inflection of the ventilation vs. time curve, at the beginning of a consistent increase in the ventilatory equivalent for O2 (minute ventilation/ oxygen consumption) without a concomitant increase in the ventilatory equivalent for carbon dioxide (minute ventilation/carbon dioxide production), and at the beginning of an increase in expired oxygen fraction.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86914743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Barbiero, R. Carloto, D. S. Pereira, Gabriela C. Schwantes, M. M. Guimarães, Maíra Ribas Goulart, D. Schuh, L. Pellanda
Background: Long-term outcomes of patients with Fontan circulation are uncertain regarding the prevalence and role of risk factors (RFs) such as increased body mass index (BMI), arterial hypertension, and hypercholesterolemia. Objectives: To describe the prevalence of RFs in patients with univentricular heart, with variable follow-up times. Methods: This mixed cohort study was performed with 66 patients, who underwent blood count, fasting blood glucose, C-reactive protein (CRP), and lipid profile tests; systolic/diastolic blood pressure (SBP/DBP) measurements; and anthropometric and sociodemographic data collection. Cardiovascular RFs among first-degree relatives and physical activity habits were also assessed. Prevalence was described using proportions, with a 95% confidence interval. Continuous variables (height, weight, age, SBP, DBP) were described as means and standard deviations (m±SD). Associations between RFs were assessed using chi-squared or Fisher’s exact tests. Spearman’s correlation was used for analyzing CRP and the presence of 2 or more RFs. The Shapiro-Wilk test was used to check for data normality. Statistical significance considered p<0.05. Results: In our population, 19.7% were overweight, mean SBP was 89.44±37.4, and mean DBP was 60.0±26.08. The most prevalent diseases in the interviewees’ families were systemic arterial hypertension (30.3%), obesity (16.7%), and 2 or more cardiovascular RFs among first-degree relatives (13.8%). We observed a trend towards significance between the presence of 2 familial RFs and overweight, as well as a risk profile for cardiovascular disease. There was an association between the BMI percentile, the presence of 2 or more RFs (p<0.05), and CRP (p<0.01). Conclusions: Overweight is common in patients with univentricular heart, being related to more than 2 cardiovascular RFs among first-degree relatives; physical inactivity and changes in lipid profiles are also frequent.
{"title":"Cardiovascular Risk Factors in Children and Adolescents with Fontan Circulation","authors":"S. Barbiero, R. Carloto, D. S. Pereira, Gabriela C. Schwantes, M. M. Guimarães, Maíra Ribas Goulart, D. Schuh, L. Pellanda","doi":"10.36660/ijcs.20200357","DOIUrl":"https://doi.org/10.36660/ijcs.20200357","url":null,"abstract":"Background: Long-term outcomes of patients with Fontan circulation are uncertain regarding the prevalence and role of risk factors (RFs) such as increased body mass index (BMI), arterial hypertension, and hypercholesterolemia. Objectives: To describe the prevalence of RFs in patients with univentricular heart, with variable follow-up times. Methods: This mixed cohort study was performed with 66 patients, who underwent blood count, fasting blood glucose, C-reactive protein (CRP), and lipid profile tests; systolic/diastolic blood pressure (SBP/DBP) measurements; and anthropometric and sociodemographic data collection. Cardiovascular RFs among first-degree relatives and physical activity habits were also assessed. Prevalence was described using proportions, with a 95% confidence interval. Continuous variables (height, weight, age, SBP, DBP) were described as means and standard deviations (m±SD). Associations between RFs were assessed using chi-squared or Fisher’s exact tests. Spearman’s correlation was used for analyzing CRP and the presence of 2 or more RFs. The Shapiro-Wilk test was used to check for data normality. Statistical significance considered p<0.05. Results: In our population, 19.7% were overweight, mean SBP was 89.44±37.4, and mean DBP was 60.0±26.08. The most prevalent diseases in the interviewees’ families were systemic arterial hypertension (30.3%), obesity (16.7%), and 2 or more cardiovascular RFs among first-degree relatives (13.8%). We observed a trend towards significance between the presence of 2 familial RFs and overweight, as well as a risk profile for cardiovascular disease. There was an association between the BMI percentile, the presence of 2 or more RFs (p<0.05), and CRP (p<0.01). Conclusions: Overweight is common in patients with univentricular heart, being related to more than 2 cardiovascular RFs among first-degree relatives; physical inactivity and changes in lipid profiles are also frequent.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89489126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iury Matheus Lima Cavalcanti, Cristian Rodrigues do Nascimento, P. P. Tenório, T. Araújo
Background: Obesity is a public health problem and has been associated with the development of metabolic disorders that have a strong relationship with the onset of cardiovascular diseases (CVD). Objective: The objective was to analyze the influence of abdominal obesity (AO) on systemic arterial hypertension (SAH) and on the lipid profile in cardiovascular risk stratification in adult women. Methods: Altogether, 91 women participated in the research. Lifestyle information was collected, in addition to the analysis of clinical measures of cardiovascular risk and biochemical parameters. Unpaired Student's t-test, logistic regression, and Pearson's correlation were performed for data analysis, with a value of p <0.05 considered significant. Results: The prevalence of AO was 62.6%. Logistic regression showed that AO increased the chance of developing SAH by 2.9-fold. The same behavior was observed in the TG/HDL-c lipid ratio (3.93 ± 0.3 vs. 2.16 ± 0.2), representing an 82% increase in obese women. The present study also demonstrated that the best anthropometric parameter to analyze cardiovascular risk in the studied population was the waist/height ratio (AUC = 0.707). Conclusions: It can therefore be concluded that AO plays a significant role in the development of SAH and changes in lipid values that predict increased cardiovascular risk, configuring a strong influence factor for CVD.
背景:肥胖是一个公共卫生问题，与代谢紊乱的发展有关，代谢紊乱与心血管疾病(CVD)的发病有很强的关系。目的:目的是分析腹部肥胖(AO)对成年女性全身性动脉高血压(SAH)和心血管危险分层中脂质谱的影响。方法:共有91名女性参与了研究。收集生活方式信息，分析心血管风险的临床指标和生化参数。数据分析采用Unpaired Student t检验、logistic回归和Pearson相关分析，p <0.05为显著性。结果:AO患病率为62.6%。Logistic回归显示，AO使SAH发生的几率增加了2.9倍。在TG/HDL-c脂质比率(3.93±0.3 vs. 2.16±0.2)中观察到同样的行为，肥胖女性增加了82%。本研究还表明，分析研究人群心血管风险的最佳人体测量参数是腰高比(AUC = 0.707)。结论:因此可以得出结论，AO在SAH的发展和预测心血管风险增加的脂质值变化中起着重要作用，是CVD的一个重要影响因素。
{"title":"Analysis of the Influence of Abdominal Obesity on Systemic Arterial Hypertension and on the Lipid Profile on Cardiometabolic Risk Stratification in Adult Women","authors":"Iury Matheus Lima Cavalcanti, Cristian Rodrigues do Nascimento, P. P. Tenório, T. Araújo","doi":"10.36660/ijcs.20200415","DOIUrl":"https://doi.org/10.36660/ijcs.20200415","url":null,"abstract":"Background: Obesity is a public health problem and has been associated with the development of metabolic disorders that have a strong relationship with the onset of cardiovascular diseases (CVD). Objective: The objective was to analyze the influence of abdominal obesity (AO) on systemic arterial hypertension (SAH) and on the lipid profile in cardiovascular risk stratification in adult women. Methods: Altogether, 91 women participated in the research. Lifestyle information was collected, in addition to the analysis of clinical measures of cardiovascular risk and biochemical parameters. Unpaired Student's t-test, logistic regression, and Pearson's correlation were performed for data analysis, with a value of p <0.05 considered significant. Results: The prevalence of AO was 62.6%. Logistic regression showed that AO increased the chance of developing SAH by 2.9-fold. The same behavior was observed in the TG/HDL-c lipid ratio (3.93 ± 0.3 vs. 2.16 ± 0.2), representing an 82% increase in obese women. The present study also demonstrated that the best anthropometric parameter to analyze cardiovascular risk in the studied population was the waist/height ratio (AUC = 0.707). Conclusions: It can therefore be concluded that AO plays a significant role in the development of SAH and changes in lipid values that predict increased cardiovascular risk, configuring a strong influence factor for CVD.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"463 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88879989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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