B. F. O. Gomes, Armando Luis Cantisano, I. Menezes, A. Azevedo, Thiago Lenoir da Silva, Valdilene Lima Silva, G. P. Dutra, S. A. M. Paula, B. F. S. Mendes, P. R. Carmo, B. B. Pereira, J. L. Petriz, G. Oliveira
Abstract Background Literature is scarce on echocardiographic characteristics of COVID-19 patients admitted to the intensive care unit (ICU). Objectives To describe echocardiographic characteristics of ICU COVID-19 patients and associate them with clinical signals/symptoms, laboratory findings and outcomes. Methods Patients with RT-PCR-confirmed COVID-19, admitted to the ICU, who underwent echocardiography were included. Clinical characteristics associated with an abnormal echocardiogram (systolic ventricular dysfunction of any degree — left and/or right ventricle — and/or high filling pressures and/or moderate to severe pericardial effusion) were analyzed. Groups were compared using the Student's t-test, chi-square, and logistic regression. A p < 0.05 was considered statistically significant. Results A total of 140 patients met inclusion criteria, and 74 (52.9%) had an abnormal echocardiogram. A low number of left and right ventricular systolic dysfunction was observed, and 35% of the population had a normal diastolic function. In the univariate analysis, characteristics associated with abnormal echocardiogram were age, chronic kidney disease, elevated troponin, previous heart failure, and simplified acute physiology score 3 (SAPS 3). In the regression model, troponin and SAPS3 score were independent markers of abnormal echocardiogram. An abnormal echocardiogram was associated with a higher prevalence of in-hospital death (RR 2.10; 95% CI 1.04-4.24) and orotracheal intubation (RR 2.3; 95% CI 1.14-4.78). Conclusions COVID-19 has little effect on ventricular function, but it is common to find increased filling pressures. Elevated serum troponin level and SAPS3 score were the independent markers of an abnormal echocardiogram. In addition, the prevalence of in-hospital death and need for mechanical ventilation were higher in patients with abnormal echocardiogram.
背景关于新冠肺炎重症监护病房(ICU)住院患者超声心动图特征的文献很少。目的探讨重症监护室COVID-19患者的超声心动图特征，并将其与临床信号/症状、实验室检查结果和转归联系起来。方法选取经rt - pcr确诊的新冠肺炎住院患者并行超声心动图检查。分析了超声心动图异常的临床特征(任何程度的收缩期心室功能障碍-左心室和/或右心室-和/或高充盈压力和/或中度至重度心包积液)。组间比较采用学生t检验、卡方检验和逻辑回归。p < 0.05为差异有统计学意义。结果140例患者符合入选标准，超声心动图异常74例(52.9%)。左、右心室收缩功能不全发生率低，35%的患者舒张功能正常。在单因素分析中，与超声心动图异常相关的特征是年龄、慢性肾脏疾病、肌钙蛋白升高、既往心力衰竭和简化急性生理评分3 (SAPS 3)。在回归模型中，肌钙蛋白和SAPS3评分是超声心动图异常的独立标志。超声心动图异常与较高的院内死亡发生率相关(RR 2.10;95% CI 1.04-4.24)和经气管插管(RR 2.3;95% ci 1.14-4.78)。结论COVID-19对心室功能影响不大，但常见的是充盈压力升高。血清肌钙蛋白水平和SAPS3评分升高是超声心动图异常的独立标志。此外，超声心动图异常患者的院内死亡患病率和机械通气需求较高。
{"title":"Echocardiogram in Critically ill Patients with COVID-19: ECOVID Study","authors":"B. F. O. Gomes, Armando Luis Cantisano, I. Menezes, A. Azevedo, Thiago Lenoir da Silva, Valdilene Lima Silva, G. P. Dutra, S. A. M. Paula, B. F. S. Mendes, P. R. Carmo, B. B. Pereira, J. L. Petriz, G. Oliveira","doi":"10.36660/ijcs.20210114","DOIUrl":"https://doi.org/10.36660/ijcs.20210114","url":null,"abstract":"Abstract Background Literature is scarce on echocardiographic characteristics of COVID-19 patients admitted to the intensive care unit (ICU). Objectives To describe echocardiographic characteristics of ICU COVID-19 patients and associate them with clinical signals/symptoms, laboratory findings and outcomes. Methods Patients with RT-PCR-confirmed COVID-19, admitted to the ICU, who underwent echocardiography were included. Clinical characteristics associated with an abnormal echocardiogram (systolic ventricular dysfunction of any degree — left and/or right ventricle — and/or high filling pressures and/or moderate to severe pericardial effusion) were analyzed. Groups were compared using the Student's t-test, chi-square, and logistic regression. A p < 0.05 was considered statistically significant. Results A total of 140 patients met inclusion criteria, and 74 (52.9%) had an abnormal echocardiogram. A low number of left and right ventricular systolic dysfunction was observed, and 35% of the population had a normal diastolic function. In the univariate analysis, characteristics associated with abnormal echocardiogram were age, chronic kidney disease, elevated troponin, previous heart failure, and simplified acute physiology score 3 (SAPS 3). In the regression model, troponin and SAPS3 score were independent markers of abnormal echocardiogram. An abnormal echocardiogram was associated with a higher prevalence of in-hospital death (RR 2.10; 95% CI 1.04-4.24) and orotracheal intubation (RR 2.3; 95% CI 1.14-4.78). Conclusions COVID-19 has little effect on ventricular function, but it is common to find increased filling pressures. Elevated serum troponin level and SAPS3 score were the independent markers of an abnormal echocardiogram. In addition, the prevalence of in-hospital death and need for mechanical ventilation were higher in patients with abnormal echocardiogram.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85842220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
, they still represent a significant burden of disease whose impact could be potentially avoided. Liu et al., 6 in a large meta-analysis, detected a progressive increase in the incidence of CHD in most countries around the world, predominantly of smaller defects (ventricular septal defect, atrial septal defect, and patent ductus arteriosus), most likely reflecting an improved detection through the dissemination of the use of echocardiography. 6 In a country with continental dimensions, such as Brazil, healthcare programs take on distinct aspects in each macro-region according to the available resources and local health policies. In all regions, however, the lack of diagnosis is a major issue, together with the unavailability of hospital beds, the difficulty to refer patients to specialized centers
{"title":"Epidemiological Profile: An Important Step in the Organization of Medical Care","authors":"A. Damiano","doi":"10.36660/ijcs.20230018","DOIUrl":"https://doi.org/10.36660/ijcs.20230018","url":null,"abstract":", they still represent a significant burden of disease whose impact could be potentially avoided. Liu et al., 6 in a large meta-analysis, detected a progressive increase in the incidence of CHD in most countries around the world, predominantly of smaller defects (ventricular septal defect, atrial septal defect, and patent ductus arteriosus), most likely reflecting an improved detection through the dissemination of the use of echocardiography. 6 In a country with continental dimensions, such as Brazil, healthcare programs take on distinct aspects in each macro-region according to the available resources and local health policies. In all regions, however, the lack of diagnosis is a major issue, together with the unavailability of hospital beds, the difficulty to refer patients to specialized centers","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"214 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78124349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Provenzale Titinger, V. E. Rosa, M. Ochiai, T. A. Accorsi, J. Fernandes, R. Sampaio, F. Tarasoutchi
. 3,11 Studies have demonstrated the superiority of transcatheter treatment compared to drug treatment in patients with aortic stenosis who could not undergo valve surgery. 12,13 In addition to TAVI, other techniques are available, such as “valve-in-valve”, “valve-in-mitral annular calcification”, and percutaneous clipping of the mitral valve, emerging as alternatives to surgical treatment.
{"title":"Frailty in Patients With Valve Disease: How to Assess?","authors":"David Provenzale Titinger, V. E. Rosa, M. Ochiai, T. A. Accorsi, J. Fernandes, R. Sampaio, F. Tarasoutchi","doi":"10.36660/ijcs.20210277","DOIUrl":"https://doi.org/10.36660/ijcs.20210277","url":null,"abstract":". 3,11 Studies have demonstrated the superiority of transcatheter treatment compared to drug treatment in patients with aortic stenosis who could not undergo valve surgery. 12,13 In addition to TAVI, other techniques are available, such as “valve-in-valve”, “valve-in-mitral annular calcification”, and percutaneous clipping of the mitral valve, emerging as alternatives to surgical treatment.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76734697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. C. A. Moraes, R. Santos, Joel Campos de Campos, Aline Carolina Castro Mota, Fernando Rocha Pessoa, Dayanne Coutinho Sarges, Davi Alexandrino Moraes, D. S. M. Souza
Abstract Background Recent reports in the literature have indicated that infection by coronavirus disease 2019 (COVID-19) causes cardiac complications, such as heart failure, arrhythmia, myocardial infarction, and even fulminant myocarditis. These complications have been identified as the cause of death in some patients infected with SARS-CoV-2. Objectives To analyze echocardiographic and electrocardiographic changes, treatments used, and clinical outcomes in patients with myocarditis and COVID-19. Methods The items described for Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were followed. This review included articles in English, Portuguese, and Spanish that reported cardiac involvement, injury, or myocardial inflammation in patients who acquired COVID-19 (SARS-CoV-2). Results Five databases were consulted to find 1,726 articles. After applying the eligibility criteria, a total of 22 studies were considered qualified. ST-segment (section of the electrocardiogram corresponding the end of the S wave to the beginning of the T wave) elevation and tachyarrhythmia were the most common changes found in the electrocardiographic analysis of patients affected with COVID-19. Concerning echocardiography, there was a high frequency of decreased ejection fraction and occurrence of pericardial effusion. Conclusion This systematic review provides a potential tool for the analysis of cardiac changes and implications caused in patients affected by SARS-CoV-2 infection, with emphasis on the presence of tachyarrhythmia on electrocardiogram (ECG) and decreased ejection fraction on echocardiogram.
{"title":"Covid-19 and Heart Involvement: A Systematic Review of Literature","authors":"F. C. A. Moraes, R. Santos, Joel Campos de Campos, Aline Carolina Castro Mota, Fernando Rocha Pessoa, Dayanne Coutinho Sarges, Davi Alexandrino Moraes, D. S. M. Souza","doi":"10.36660/ijcs.20220035","DOIUrl":"https://doi.org/10.36660/ijcs.20220035","url":null,"abstract":"Abstract Background Recent reports in the literature have indicated that infection by coronavirus disease 2019 (COVID-19) causes cardiac complications, such as heart failure, arrhythmia, myocardial infarction, and even fulminant myocarditis. These complications have been identified as the cause of death in some patients infected with SARS-CoV-2. Objectives To analyze echocardiographic and electrocardiographic changes, treatments used, and clinical outcomes in patients with myocarditis and COVID-19. Methods The items described for Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were followed. This review included articles in English, Portuguese, and Spanish that reported cardiac involvement, injury, or myocardial inflammation in patients who acquired COVID-19 (SARS-CoV-2). Results Five databases were consulted to find 1,726 articles. After applying the eligibility criteria, a total of 22 studies were considered qualified. ST-segment (section of the electrocardiogram corresponding the end of the S wave to the beginning of the T wave) elevation and tachyarrhythmia were the most common changes found in the electrocardiographic analysis of patients affected with COVID-19. Concerning echocardiography, there was a high frequency of decreased ejection fraction and occurrence of pericardial effusion. Conclusion This systematic review provides a potential tool for the analysis of cardiac changes and implications caused in patients affected by SARS-CoV-2 infection, with emphasis on the presence of tachyarrhythmia on electrocardiogram (ECG) and decreased ejection fraction on echocardiogram.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87075847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vivian de Moraes Coelho, Camila Oliveira Sinhoroto, Patrícia Magnaboso, Maria Beatriz Guimarães Raponi, Maria Angélica Melo e Oliveira, Omar Pereira de Almeida, V. Figueiredo
Introduction : Nurses from the night shift are exposed to sleep deprivation, which is associated with circadian rhythm alteration, lifestyle changes, psychosocial stress, and, consequently, increased risk of blood pressure (BP) deregulation and hypertension. Objective : To analyze risk factors associated with elevated BP levels in nursing workers. Methods : A transversal, quantitative study was conducted with 172 nursing professionals of a large hospital in the state of Minas Gerais, Brazil. The following data were collected: anthropometric and BP measurements, sociodemographic characteristics, clinical variables, and lifestyle habits. Results were evaluated by bivariate analysis and logistic regression. The level of significance adopted in the statistical analysis was 5%. Results : Participants’ average age was 42.7 ± 9.6 years old; 86.6% (n = 149) were female, and 20.3% (n = 35) had previous diagnosis of hypertension. Overweight and obesity (odds ratio [OR]: 2.187, 95% confidence interval [CI]: 1.060 – 4.509) and night shift (OR: 2.100, CI 95%: 1.061 – 4.158) were statistically significant (p < 0.05) for increased risk of elevated BP level. Conclusion : Excessive weight and night shift were significant factors for increased BP in nursing workers.
{"title":"Factors Associated With Elevated Blood Pressure in Nursing Workers","authors":"Vivian de Moraes Coelho, Camila Oliveira Sinhoroto, Patrícia Magnaboso, Maria Beatriz Guimarães Raponi, Maria Angélica Melo e Oliveira, Omar Pereira de Almeida, V. Figueiredo","doi":"10.36660/ijcs.20220001","DOIUrl":"https://doi.org/10.36660/ijcs.20220001","url":null,"abstract":"Introduction : Nurses from the night shift are exposed to sleep deprivation, which is associated with circadian rhythm alteration, lifestyle changes, psychosocial stress, and, consequently, increased risk of blood pressure (BP) deregulation and hypertension. Objective : To analyze risk factors associated with elevated BP levels in nursing workers. Methods : A transversal, quantitative study was conducted with 172 nursing professionals of a large hospital in the state of Minas Gerais, Brazil. The following data were collected: anthropometric and BP measurements, sociodemographic characteristics, clinical variables, and lifestyle habits. Results were evaluated by bivariate analysis and logistic regression. The level of significance adopted in the statistical analysis was 5%. Results : Participants’ average age was 42.7 ± 9.6 years old; 86.6% (n = 149) were female, and 20.3% (n = 35) had previous diagnosis of hypertension. Overweight and obesity (odds ratio [OR]: 2.187, 95% confidence interval [CI]: 1.060 – 4.509) and night shift (OR: 2.100, CI 95%: 1.061 – 4.158) were statistically significant (p < 0.05) for increased risk of elevated BP level. Conclusion : Excessive weight and night shift were significant factors for increased BP in nursing workers.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91180460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Petronilho, M. O. Gois, C. Sakaguchi, M. C. M. Frade, M. Roscani, A. Catai
Background: The incidence of diabetes mellitus in younger adults is rising over the years. The diabetic population has an increased risk of developing heart failure, and diabetic individuals with heart failure have four times greater mortality rate. Studies results about exercise effect on left ventricular function in type 2 diabetes mellitus are heterogenous. Objective : This review aimed to analyze the effects of physical exercise on left ventricular dysfunction in type 2 diabetes mellitus (T2DM). Methods: Only randomized clinical trials with humans published in English were included. Inclusion criteria were studies with type 2 diabetes patients, physical exercise, control group and left ventricular function. Exclusion criteria were studies with animals, children, teenagers, elderly individuals and athletes, presence of diet intervention, and patients with type 1 diabetes, cancer, cardiac, pulmonary, or neurological diseases. Electronic databases PubMed, Web of Science, Cochrane, and Scopus were last searched in September 2021. Risk of bias was assessed by the Physiotherapy Evidence Database (PEDro) scale. Results: Five studies were included, representing 314 diabetic individuals submitted to resistance and aerobic exercise training. Of the variables analyzed, physical exercise improved peak torsion (PTo), global longitudinal strain, global strain rate (GSR), time to peak untwist rate (PUTR), early diastolic filling rate (EDFR) and peak early diastolic strain rate (PEDSR). Conclusion: To our knowledge, this is the first systematic review on the effects of exercise on left ventricular function in T2DM including only randomized clinical trials with humans. Physical exercise seems to improve systolic and diastolic strain, twist, and torsion. High intensity exercise was reported to be superior to moderate intensity exercise in one study. This review was limited by the small number of studies and their heterogeneity regarding exercise protocols, follow-up period, exercise supervision and left ventricular function variables analyzed. This review was registered in PROSPERO (CRD42021234964).
背景:近年来，青年人糖尿病的发病率呈上升趋势。糖尿病人群患心力衰竭的风险增加，糖尿病患者合并心力衰竭的死亡率是正常人的四倍。运动对2型糖尿病左心室功能影响的研究结果参差不齐。目的:本综述旨在分析体育锻炼对2型糖尿病(T2DM)左心室功能障碍的影响。方法:只纳入用英文发表的人类随机临床试验。纳入标准为2型糖尿病患者、体育锻炼、对照组和左心室功能研究。排除标准为动物、儿童、青少年、老年人和运动员、存在饮食干预、1型糖尿病、癌症、心脏、肺部或神经系统疾病患者的研究。PubMed、Web of Science、Cochrane和Scopus等电子数据库最后一次检索是在2021年9月。偏倚风险通过物理治疗证据数据库(PEDro)量表进行评估。结果:纳入了5项研究，代表314名糖尿病患者进行了抵抗和有氧运动训练。在分析的变量中，体育锻炼提高了峰值扭转率(PTo)、整体纵向应变、整体应变率(GSR)、至峰值解捻率(PUTR)、舒张早期充盈率(EDFR)和舒张早期峰值应变率(PEDSR)。结论:据我们所知，这是第一个关于运动对T2DM患者左心室功能影响的系统综述，仅包括随机临床试验。体育锻炼似乎可以改善收缩期和舒张期的紧张、扭曲和扭转。一项研究报告高强度运动优于中等强度运动。本综述受限于研究数量少，且在运动方案、随访期、运动监督和左心室功能变量分析方面存在异质性。本综述已在PROSPERO注册(CRD42021234964)。
{"title":"Effects of Physical Exercise on Left Ventricular Function in Type 2 Diabetes Mellitus: A Systematic Review","authors":"A. Petronilho, M. O. Gois, C. Sakaguchi, M. C. M. Frade, M. Roscani, A. Catai","doi":"10.36660/ijcs.20220020","DOIUrl":"https://doi.org/10.36660/ijcs.20220020","url":null,"abstract":"Background: The incidence of diabetes mellitus in younger adults is rising over the years. The diabetic population has an increased risk of developing heart failure, and diabetic individuals with heart failure have four times greater mortality rate. Studies results about exercise effect on left ventricular function in type 2 diabetes mellitus are heterogenous. Objective : This review aimed to analyze the effects of physical exercise on left ventricular dysfunction in type 2 diabetes mellitus (T2DM). Methods: Only randomized clinical trials with humans published in English were included. Inclusion criteria were studies with type 2 diabetes patients, physical exercise, control group and left ventricular function. Exclusion criteria were studies with animals, children, teenagers, elderly individuals and athletes, presence of diet intervention, and patients with type 1 diabetes, cancer, cardiac, pulmonary, or neurological diseases. Electronic databases PubMed, Web of Science, Cochrane, and Scopus were last searched in September 2021. Risk of bias was assessed by the Physiotherapy Evidence Database (PEDro) scale. Results: Five studies were included, representing 314 diabetic individuals submitted to resistance and aerobic exercise training. Of the variables analyzed, physical exercise improved peak torsion (PTo), global longitudinal strain, global strain rate (GSR), time to peak untwist rate (PUTR), early diastolic filling rate (EDFR) and peak early diastolic strain rate (PEDSR). Conclusion: To our knowledge, this is the first systematic review on the effects of exercise on left ventricular function in T2DM including only randomized clinical trials with humans. Physical exercise seems to improve systolic and diastolic strain, twist, and torsion. High intensity exercise was reported to be superior to moderate intensity exercise in one study. This review was limited by the small number of studies and their heterogeneity regarding exercise protocols, follow-up period, exercise supervision and left ventricular function variables analyzed. This review was registered in PROSPERO (CRD42021234964).","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88948133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabela Madruga, T. D. Moraes, C. Prado, C. Baldini, A. Braga
Background: Cardiac anomalies are the most prevalent congenital malformations among live births in the world. In Brazil, it is estimated that nearly 25,757 new cases occur each year, and the Southeast region presents the highest prevalence, with 10 new cases/1,000 live births. Objective: The aim of this study is to evaluate the epidemiology of congenital heart disease (CHD) in the state of São Paulo. Methods: This is a cross-sectional and time-series observational study with data from the Brazilian Information System on Live Births. Heart-related cardiac malformation cases — International Classification of Diseases (ICD) 10th revision Q20.0 to Q24.9 — were selected from January 2010 to December 2018, in the state of São Paulo, Brazil. This study analyzed rates of malformations per year and investigated associated factors, using single and multiple logistic regression models. The significance level adopted in this study was 5%. Results: The highest cardiac malformation rate was in the São Paulo metropolitan region (2.84:1000), while the lowest was found in the region of Franca (0.3:1000). The most frequent defect was interatrial communication (38.2%). The main associated factors observed in this study were prematurity of 22 to 27 weeks (OR=4,401 95% CI: 3,796-5,104) — CI: Confidence Interval; OR: Odds ratio —, mother’s age between 35 and 49 years of age (OR=1,602 95% CI: 1,525-1,682), yellow race (OR=1,481 95% CI: 1,235-1,775), triple or more pregnancy (OR=1,438 95% CI: 1,004-2,060), and history of a dead child (OR=1,213 95% CI: 1,152-1,277). Conclusion: The main factors associated with this outcome, which are part of the obstetric history of mothers, should be addressed and considered when pregnancy is a planned event.
{"title":"Associated Factors with Congenital Heart Disease in the Most Populated State of Brazil Between 2010 and 2018","authors":"Isabela Madruga, T. D. Moraes, C. Prado, C. Baldini, A. Braga","doi":"10.36660/ijcs.20210283","DOIUrl":"https://doi.org/10.36660/ijcs.20210283","url":null,"abstract":"Background: Cardiac anomalies are the most prevalent congenital malformations among live births in the world. In Brazil, it is estimated that nearly 25,757 new cases occur each year, and the Southeast region presents the highest prevalence, with 10 new cases/1,000 live births. Objective: The aim of this study is to evaluate the epidemiology of congenital heart disease (CHD) in the state of São Paulo. Methods: This is a cross-sectional and time-series observational study with data from the Brazilian Information System on Live Births. Heart-related cardiac malformation cases — International Classification of Diseases (ICD) 10th revision Q20.0 to Q24.9 — were selected from January 2010 to December 2018, in the state of São Paulo, Brazil. This study analyzed rates of malformations per year and investigated associated factors, using single and multiple logistic regression models. The significance level adopted in this study was 5%. Results: The highest cardiac malformation rate was in the São Paulo metropolitan region (2.84:1000), while the lowest was found in the region of Franca (0.3:1000). The most frequent defect was interatrial communication (38.2%). The main associated factors observed in this study were prematurity of 22 to 27 weeks (OR=4,401 95% CI: 3,796-5,104) — CI: Confidence Interval; OR: Odds ratio —, mother’s age between 35 and 49 years of age (OR=1,602 95% CI: 1,525-1,682), yellow race (OR=1,481 95% CI: 1,235-1,775), triple or more pregnancy (OR=1,438 95% CI: 1,004-2,060), and history of a dead child (OR=1,213 95% CI: 1,152-1,277). Conclusion: The main factors associated with this outcome, which are part of the obstetric history of mothers, should be addressed and considered when pregnancy is a planned event.","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83198835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Summary COP researchers have already conducted very important research that must be expanded, including larger and more diverse and better defined populations, with patients around the world, different cardiovascular and non-cardiovascular diseases, tests using a treadmill (more experience with treadmill CPET is needed), and evaluation of the prognostic values of sub-maximal parameters, such as COP and eventually VO 2 at VT1, versus the maximal parameters, such as pVO 2 , VE/VCO 2 slope, and OUES. A clear answer is needed: [...]
{"title":"Cardiorespiratory Optimal Point: A New Kid in the Block or an Established Star?","authors":"Miguel Mendes","doi":"10.36660/ijcs.20230124","DOIUrl":"https://doi.org/10.36660/ijcs.20230124","url":null,"abstract":"Summary COP researchers have already conducted very important research that must be expanded, including larger and more diverse and better defined populations, with patients around the world, different cardiovascular and non-cardiovascular diseases, tests using a treadmill (more experience with treadmill CPET is needed), and evaluation of the prognostic values of sub-maximal parameters, such as COP and eventually VO 2 at VT1, versus the maximal parameters, such as pVO 2 , VE/VCO 2 slope, and OUES. A clear answer is needed: [...]","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135913530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mateus Correa Lech, Joel Stefani, Lucas Fernando Fabra, Miguel Gus, Fernando Pivatto
Background The SHARPEN score was developed to predict in-hospital mortality in patients hospitalized for infective endocarditis (IE), undergoing or not undergoing cardiac surgery. A comparison with other available scores has not yet been carried out. Objective To evaluate the performance of the SHARPEN score in predicting in-hospital mortality in patients hospitalized for IE undergoing cardiac surgery and compare it with that of both nonspecific and IE-specific surgical scores. Methods Retrospective cohort study including all admissions of patients ≥18 years [...]
{"title":"Analysis of the SHARPEN Score in the Prediction of In-Hospital Mortality of Patients With Infective Endocarditis Undergoing Cardiac Surgery","authors":"Mateus Correa Lech, Joel Stefani, Lucas Fernando Fabra, Miguel Gus, Fernando Pivatto","doi":"10.36660/ijcs.20230061","DOIUrl":"https://doi.org/10.36660/ijcs.20230061","url":null,"abstract":"Background The SHARPEN score was developed to predict in-hospital mortality in patients hospitalized for infective endocarditis (IE), undergoing or not undergoing cardiac surgery. A comparison with other available scores has not yet been carried out. Objective To evaluate the performance of the SHARPEN score in predicting in-hospital mortality in patients hospitalized for IE undergoing cardiac surgery and compare it with that of both nonspecific and IE-specific surgical scores. Methods Retrospective cohort study including all admissions of patients ≥18 years [...]","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136008228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
drugs goes far beyond providing the access of medications, when in fact it should include educational issues designed specifically for the cultural background of that community or population
毒品远远超出了提供药物的途径，事实上，它应该包括专门为该社区或人口的文化背景设计的教育问题
{"title":"Challenging Health Literacy, Patient Knowledge, and Adherence to Oral Anticoagulation in Primary Care Units","authors":"A. Mansur","doi":"10.36660/ijcs.20230095","DOIUrl":"https://doi.org/10.36660/ijcs.20230095","url":null,"abstract":"drugs goes far beyond providing the access of medications, when in fact it should include educational issues designed specifically for the cultural background of that community or population","PeriodicalId":32690,"journal":{"name":"International Journal of Cardiovascular Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78475707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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