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To study visual evoked potential in patients with optic nerve diseases 研究视神经疾病患者的视觉诱发电位
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_58_22
Kavita Poonia, R. Tuli, Gaurav Sharma, Amit Bhardwaj
To study Visual Evoked Potential in patients with Optic Nerve diseases. Study design and settings: Cross – Sectional study. 72 patients were included in our study, aged 12 years and above, diagnosed as optic nerve diseases like optic neuritis, Nonarteritc ischemic optic neuropathy (NAION), hereditary, nutritional and compressive optic neuropathy etc. Flash and Pattern VEPs were used. VEP amplitude and latency were noted. Out of total 144 eyes, 107 eyes were affected. Ethambutol induced Toxic optic neuropathy was the most common etiology, followed by secondary optic neuropathy, idiopathic, traumatic optic neuropathy, optic neuritis, NAION, compressive and post CRAO (Central Retinal Artery Occlusion) optic neuropathy. Mean latency of all affected eyes was 132±22.5 msec. mean amplitude of the all affected eyes was 6.36±2.1 microvolt. Latency was moderately delayed (110-140 msec) in 45.8%, while severely delayed (>140 msec) in 40.3% of total eyes. Amplitude was reduced in 36.5% of total eyes. Prolonged latency with normal amplitude was found in most of the eyes with optic neuritis while latency was also prolonged in fellow eyes of optic neuritis. In case of NAION prolonged latency and reduced amplitude was found in all eyes. Flash or pattern VEP can be used as an important tool for diagnosis of optic neuropathies or revealing of recurrence of disease and for follow up. VEP can also be used to detect subclinical damage in the fellow eyes of optic neuritis and also useful in differentiating the optic neuritis from ischemic optic neuropathy.
研究视神经疾病患者的视觉诱发电位。研究设计和设置:横断面研究。 研究共纳入 72 名患者,年龄在 12 岁及以上,被诊断为视神经疾病,如视神经炎、非动脉缺血性视神经病变(NAION)、遗传性、营养性和压迫性视神经病变等。使用闪光和模式 VEP。记录 VEP 振幅和潜伏期。 在总共 144 只眼睛中,107 只眼睛受到影响。乙胺丁醇诱发的中毒性视神经病变是最常见的病因,其次是继发性视神经病变、特发性、外伤性视神经病变、视神经炎、NAION、压迫性和 CRAO(视网膜中央动脉闭塞)后视神经病变。所有患眼的平均潜伏期为 132±22.5 毫秒,平均振幅为 6.36±2.1 微伏。中度延迟(110-140 毫秒)占 45.8%,严重延迟(大于 140 毫秒)占 40.3%。36.5%的眼睛振幅减小。大多数视神经炎患者的眼球潜伏期延长,但振幅正常,而其他视神经炎患者的眼球潜伏期也延长。在非结节性视网膜炎患者中,所有眼的潜伏期都延长,振幅减小。 闪光或模式 VEP 可作为诊断视神经病变或揭示疾病复发及随访的重要工具。VEP 还可用于检测视神经炎同侧眼的亚临床损害,也有助于区分视神经炎和缺血性视神经病变。
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引用次数: 0
The ocular manifestations of cerebral venous sinus thrombosis: An uncommon form of stroke 脑静脉窦血栓形成的眼部表现:一种不常见的中风形式
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_90_23
A. Mishra, Ruchi Shukla
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引用次数: 0
A case–control study of tear film functions in patients with unilateral pterygium at a Tertiary Care Center in Marathwada 马拉瓦达省一家三级医疗中心对单侧翼状胬肉患者泪膜功能的病例对照研究
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_121_23
A. Awargaonkar, Sagar Janrao, SurajkumarShobhalal Kuril
Pterygium is a very common ocular surface disorder. Tear film dysfunctions have been reported in subjects with pterygium. We aim to study the correlation between pterygium and dry eye disease in patients with unilateral pterygium. A case–control study of patients with unilateral pterygium was undertaken after ethical clearance from the institutional ethics committee. Eighty-seven patients with unilateral pterygium were included in the study. Tear film break-up time (TBUT), Rose Bengal staining (RBS), and Schirmer’s test 1 were performed in both eyes of the patients. Test results were compared with contralateral normal eye of the same patient. Data were analyzed using t-test and Chi-square test. P <0.05 was considered statistically significant. The tear film function parameters, namely Schirmer 1, TBUT, and RBS in the study group, were statistically different as compared to the control group. The mean of TBUT was 8.19 ± 1.87 s in pterygium eyes and 11.83 ± 1.69 s in contralateral normal eyes. The mean of Schirmer’s 1 was 10.65 ± 3.69 mm in pterygium eyes and 16.37 ± 4.82 mm in contralateral eyes with no pterygium. There was a statistically significant difference in the values of tear film function between eyes with pterygium and contralateral normal eyes.
翼状胬肉是一种非常常见的眼表疾病。有报告称翼状胬肉患者存在泪膜功能障碍。 我们旨在研究单侧翼状胬肉患者的翼状胬肉与干眼症之间的相关性。 在获得机构伦理委员会的伦理许可后,我们对单侧翼状胬肉患者进行了病例对照研究。 研究共纳入了 87 名单侧翼状胬肉患者。对患者的双眼进行了泪膜破裂时间(TBUT)、玫瑰红染色(RBS)和施尔默试验 1。测试结果与同一患者对侧正常眼进行比较。 数据采用 t 检验和卡方检验进行分析。P<0.05为差异有统计学意义。 与对照组相比,研究组的泪膜功能参数,即 Schirmer 1、TBUT 和 RBS 有统计学差异。翼状胬肉患者的 TBUT 平均值为 8.19 ± 1.87 秒,对侧正常眼为 11.83 ± 1.69 秒。翼状胬肉眼的 Schirmer's 1 平均值为 10.65 ± 3.69 mm,对侧无翼状胬肉眼的 Schirmer's 1 平均值为 16.37 ± 4.82 mm。 有翼状胬肉的眼睛和对侧正常眼睛的泪膜功能值在统计学上有显著差异。
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引用次数: 0
Tick manifestation of the upper eyelid 上眼睑的蜱虫表现
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_18_24
Shalaka Pissurlencar, Devika S. Joshi, Shrikant Joshi
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引用次数: 0
Assessing knowledge, attitude, and practice regarding conjunctivitis among patients 评估患者对结膜炎的认识、态度和做法
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_131_23
Maxwell Silva, P. V. Bhailume, Nachiket Pargaonkar, Malcolm Silva
(1) To assess the knowledge, attitude, and practice about conjunctivitis among patients. (2) To educate society regarding preventive and therapeutic measures. A cross-sectional study, in which 500 patients were selected as participants, knowledge, attitude, and practice were assessed regarding conjunctivitis using prevalidate questionnaire, which contains 20 questions. Descriptive statistics were used to elaborate patients’ demographic characteristics. Categorical variable was percentage while the continuous variable was conveyed as mean ± standard deviation. A significance P < 0.05 was used for comparison. All analyses were performed using the Statistical Package for the Social Science Version 20. Out of 500 distributed questionnaires, 328 were male, 172 were female, majority having age range between 25-60 years. It was seen that 370 participants (74%) have adequate knowledge regarding conjunctivitis. Patients have sufficient knowledge and awareness about conjunctivitis, yet effort should be made to bring change about conjunctivitis. Proper eye health facilities and teaching should be involved in institute health services, and early presentation to eye care centers for its treatment should be encouraged.
(1) 评估患者对结膜炎的认识、态度和做法。(2) 向社会宣传预防和治疗措施。 这项横断面研究选取了 500 名患者作为研究对象,使用包含 20 个问题的流行病学调查问卷评估了他们对结膜炎的认识、态度和做法。研究使用描述性统计来阐述患者的人口统计学特征。分类变量以百分比表示,连续变量以均数±标准差表示。比较采用显著性 P < 0.05。所有分析均使用社会科学统计软件包 20 版进行。 在发放的 500 份问卷中,男性 328 人,女性 172 人,大多数人的年龄在 25-60 岁之间。结果显示,370 名参与者(74%)对结膜炎有足够的了解。 患者对结膜炎有足够的了解和认识,但应努力改变对结膜炎的认识。应将适当的眼科保健设施和教学纳入研究所的保健服务中,并鼓励患者及早到眼科保健中心接受治疗。
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引用次数: 0
Keratoconus presentation with respect to age, gender, and severity in Western India 印度西部与年龄、性别和严重程度有关的角膜炎表现形式
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_144_23
Zalak A. Shah, Dipali Purohit, P. Danayak, Jayadatt D. Patel, Sena M. Purohit
To study the demographic profile of keratoconus (KC) patients visiting a tertiary eye care hospital in Western India. This cross-sectional, observational study included newly diagnosed KC patients visiting our hospital between January 2018 and October 2022. Patient’s demographic details (self-reported age at first presentation, age at diagnosis, and sex) and mean maximum curvature (K Max) were collected. The patients were divided into age band of 5-year groups. A subanalysis of gender and severity was performed among groups. Spearman’s correlation coefficient was used to evaluate the relationship between KC severity and age. A total of 536 patients with clinical KC were included. A self-reported age at first presentation was 19.4 ± 6.2 years. The mean age of diagnosis was 20.5 ± 6.0 years (range: 4–43 years). There were 61.6% (330) of males and 38.4% (206) of females (P < 0.01). The mean K Max value was 59.2 ± 13.3 diopter (D). The mean K Max was not significantly different between the sexes, with the exception of the age range of 24–28 years, where females had more severe KC than males (P = 0.02). Among the included patients, 38.6% (207) of patients were pediatrics (≤18 years), while 61.4% (329) were adults (>18 years). The mean K Max in pediatric KC (62.3 ± 15.1 D) was significantly higher than adult KC (57.3 ± 11.5), P < 0.01. Severity of KC did not correlate with the age of the patients (r = −0.20, P = 0.04). KC presented at a younger age with moderate-to-severe stage of the disease, indicating the need for early KC detection in our population.
目的:研究在印度西部一家三级眼科医院就诊的角膜炎(KC)患者的人口统计学特征。 这项横断面观察性研究纳入了 2018 年 1 月至 2022 年 10 月期间到我院就诊的新诊断 KC 患者。研究收集了患者的详细人口统计学资料(自我报告的首次就诊年龄、确诊年龄和性别)和平均最大曲率(K Max)。患者被分为 5 岁年龄段。对各组的性别和严重程度进行了子分析。斯皮尔曼相关系数用于评估 KC 严重程度与年龄之间的关系。 共纳入了 536 名临床 KC 患者。首次发病时的自我报告年龄为(19.4 ± 6.2)岁。平均确诊年龄为(20.5 ± 6.0)岁(范围:4-43 岁)。男性占 61.6%(330 人),女性占 38.4%(206 人)(P < 0.01)。平均最大 K 值为 59.2 ± 13.3 屈光度 (D)。除 24-28 岁年龄段的女性比男性有更严重的 KC 外(P = 0.02),男女之间的 K Max 平均值无明显差异。在纳入的患者中,38.6%(207 人)为儿童(18 岁以下),61.4%(329 人)为成人(18 岁以上)。小儿 KC 的平均 K Max(62.3 ± 15.1 D)明显高于成人 KC(57.3 ± 11.5),P < 0.01。KC 的严重程度与患者的年龄无关(r = -0.20,P = 0.04)。 中重度 KC 患者的年龄较小,这表明在我国人群中需要及早发现 KC。
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引用次数: 0
Blouse-hook injury in breastfeeding children: Canalicular laceration to corneal tear 哺乳期儿童的上衣钩伤:从管状裂伤到角膜撕裂
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_3_24
M. Agrawal, Teena Agrawal
An ocular injury in a kid is very common, especially in <5 years of age, which ranges from eye adnexa to globe injury. In breastfeeding kids, there are chances of eyelid avulsion with involvement of the canaliculus. In our case series, we report two cases of eyelid laceration and one case of corneal tear due to the use of a safety pin as a blouse hook. Our first case of a 2.5-year-old kid presented with multiple laceration of the eyelid and was managed by primary repair due to the unavailability of mini-monoka stent. The second child was managed well by the mini-monoka stent and had given excellent anatomical as well as functional outcome on 6 months of follow-up. Our third case was corneal tear which was managed well with good visual outcome without cataract formation on 6 months of follow-up.
儿童眼部受伤非常常见,尤其是 5 岁以下的儿童,从眼部附件到眼球都有可能受伤。在母乳喂养的儿童中,有可能发生眼睑撕裂并累及眼管。在我们的病例系列中,我们报告了两例眼睑撕裂伤和一例因使用安全别针作为上衣挂钩而导致的角膜撕裂伤。第一个病例是一名 2.5 岁的儿童,眼睑多处裂伤,由于没有微型单孔支架,只能进行初级修复。第二个病例使用迷你单眼皮支架治疗后效果良好,随访 6 个月后,在解剖和功能方面都取得了很好的疗效。我们的第三个病例是角膜撕裂,经过 6 个月的随访,处理得当,视力良好,没有形成白内障。
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引用次数: 0
Ocular disorders in Parkinson’s disease: A review 帕金森病的眼部疾病:综述
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_111_23
Yashi Bansal, Renu Grover
Parkinson’s disease (PD) is a common degenerative disorder characterized by decreased dopamine levels from damage to the substantia nigra causing classic motor deficits. Several ocular deficits have been recognized in association with PD such as oculomotor disturbances and diplopia, glaucoma and visual field loss, dry eye disease, color and contrast impairment, visual hallucinations, and visuospatial and visuoperceptual impairments. These disorders remain underreported, underrecognized, and poorly understood. Patients with PD are largely dependent on visual cues for compensating the motor deficits. Hence, early recognition and timely management of the above ocular disorders can lead to greater patient safety, independence, and a better quality of life.
帕金森病(Parkinson's disease,PD)是一种常见的退行性疾病,其特征是黑质受损导致多巴胺水平下降,从而引起典型的运动障碍。已发现帕金森病伴有多种眼部功能障碍,如眼球运动障碍和复视、青光眼和视野缺损、干眼症、色彩和对比度障碍、视幻觉以及视觉空间和视觉感知障碍。这些疾病仍未得到充分报道、充分认识和深入了解。帕金森病患者在很大程度上依赖视觉线索来补偿运动障碍。因此,早期识别和及时处理上述眼部疾病可提高患者的安全性、独立性和生活质量。
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引用次数: 0
Delayed vitreous prolapse causing corneal decompensation with normal Intraocular pressure: A case report 眼压正常的延迟性玻璃体脱垂导致角膜失代偿:病例报告
Pub Date : 2024-05-01 DOI: 10.4103/jcor.jcor_10_24
Prachi Sharma, Vishal Katiyar
Vitreous prolapse is a postcataract surgery complication that can further cause corneal decompensation, glaucoma, macular edema, and retinal detachment. We present a rare case report of delayed vitreous prolapse in a 55-year-old man 20 years after cataract surgery with posterior capsular rupture causing diminution of vision and central corneal decompensation. To our surprise, the intraocular pressure was 18.6 mmHg (within the normal limits). The patient underwent pars plana vitrectomy for the same and had excellent postoperative visual recovery.
玻璃体脱垂是白内障手术后的一种并发症,可进一步导致角膜失代偿、青光眼、黄斑水肿和视网膜脱离。我们报告了一例罕见的延迟性玻璃体脱垂病例,患者是一名 55 岁的男性,白内障手术后 20 年,后囊破裂导致视力下降和中央角膜失代偿。令我们惊讶的是,患者的眼压为 18.6 mmHg(在正常范围内)。为此,患者接受了玻璃体旁切除术,术后视力恢复良好。
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引用次数: 0
Isolated homonymous hemianopia: A case series 孤立性同向偏盲:一系列病例
Pub Date : 2023-09-01 DOI: 10.4103/jcor.jcor_52_23
ShreeyaK Jain, Rajani Kadri, U. Sampritha, Ajay A Kudva
The purpose of this study was to describe five case series of patients who presented with isolated homonymous hemianopia (HH) heralding the ministroke. This was a retrospective observational case series. This was a retrospective case series of five patients who presented to the outpatient department with isolated HH and was followed up for 6 months. 30-2 Humphrey's perimetric analysis and neuroimaging was done. Patients also underwent 2D ECHO and 24 h holter monitoring. These patients who presented with isolated HH had best corrected visual acuity of 6/6, N6 with Snellen's chart. Pupils and color vision were normal. On neuroimaging, one patient had infarction only in the occipital lobe. Two had infarction in the cerebellar hemispheres along with the occipital lobe and one patient had infarction in the deep white matter of temporal lobe, corona radiata, and the last patient also had chronic infarct in the frontal lobe. But all these patients presented with isolated HH. 2D ECHO and 24 h holter monitoring were within normal limits and had no neurological deficits. They were put on oral antiplatelets, statins and nutritional supplements, followed up by neurologists for 6 months and showed no neurological deficits on follow up. On finger confrontation test, hemianopia was still persistent. Isolated visual symptoms may be an early presenting characteristic of stroke. As there is a finite window of time during which therapy for stroke is effective, prompt identification of such atypical symptoms is crucial.
本研究的目的是描述五个病例系列的患者,他们表现出孤立的同名偏盲(HH),预示着小中风。这是一个回顾性观察病例系列。这是一个由五名患者组成的回顾性病例系列,他们在门诊就诊时患有孤立性HH,并接受了6个月的随访。进行30-2 Humphrey的视野分析和神经影像学检查。患者还接受了2D ECHO和24小时动态心电图监测。这些出现孤立性HH的患者的最佳矫正视力为6/6,Snellen图表显示为N6。瞳孔和色觉正常。在神经影像学检查中,一名患者仅在枕叶出现梗死。两名患者在小脑半球和枕叶发生梗死,一名患者在颞叶深部白质、放射冠发生梗死,最后一名患者也在额叶发生慢性梗死。但所有这些患者均表现为孤立性HH。2D ECHO和24 h holter监测在正常范围内,没有神经功能缺陷。他们服用了口服抗血小板药物、他汀类药物和营养补充剂,由神经学家随访6个月,随访时没有表现出神经系统缺陷。在手指对抗测试中,偏盲仍然存在。孤立的视觉症状可能是中风的早期表现特征。由于中风治疗有效的时间窗口有限,因此及时识别此类非典型症状至关重要。
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引用次数: 0
期刊
Journal of Clinical Ophthalmology and Research
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