Pub Date : 2019-01-01DOI: 10.26565/2076-0612-2019-28-06
N. Shushliapina
Introduction. Capillary changes link are closely correlated with shifts in central hemodynamics, which allows the use of microcirculation parameters as diagnostic and prognostic criteria for assessing the body as a whole. The work is aimed at increasing the efficiency of detecting microcirculatory disorders by computer capillaroscopy in patients with pathology of intranasal structures and accompanied by difficulty in nasal breathing and smell. Purpose: nature and severity analysis of intravital morphological changes in the microvessels of the nail bed in patients with pathology of the intranasal structures, accompanied by impaired nasal breathing and smell.Materials and methods: We examined 145 patients aged 18–38 years who were diagnosed with changes in intranasal structures with varying degrees of nasal obstruction and impaired sense of smell. Patients were divided into 3 groups. The first group — patients with a disease duration of 3–5 years; the second group — patients with a disease duration of up to 0.5 years; the third group — patients with a disease duration of up to 1 month. Results: Patients with intranasal structures pathology in the I and III clinical groups with a duration of nasal obstruction up to 5 years and 1 month. Changes in systemic microcirculation were significantly more frequently observed than in patients with a disease duration of up to 0.5 years. The observed tendency to disturbance of microcirculation in groups III and I is caused, first of all, by a change in the state of microvessels for sharp hypoxia (these changes are consistent with rhinomanometry) and a “breakdown” of adaptation mechanisms in the group of prolonged nasal obstruction for up to 5 years, at that time as in group II, there is an increase in the reserve of adaptation from the cardiovascular system to the conditions of nasal obstruction. Сonclusions: The study of microcirculation using capillaroscopy made it possible to study the smallest vessels, capillaries, which are the first to respond to impaired nasal breathing by changing the functional state and morphological reconstruction of the microvasculature of the bloodstream.
{"title":"Microcirculation state analysis in patients with pathology of intrinosular structures with respiratory-reference disorders","authors":"N. Shushliapina","doi":"10.26565/2076-0612-2019-28-06","DOIUrl":"https://doi.org/10.26565/2076-0612-2019-28-06","url":null,"abstract":"Introduction. Capillary changes link are closely correlated with shifts in central hemodynamics, which allows the use of microcirculation parameters as diagnostic and prognostic criteria for assessing the body as a whole. The work is aimed at increasing the efficiency of detecting microcirculatory disorders by computer capillaroscopy in patients with pathology of intranasal structures and accompanied by difficulty in nasal breathing and smell. Purpose: nature and severity analysis of intravital morphological changes in the microvessels of the nail bed in patients with pathology of the intranasal structures, accompanied by impaired nasal breathing and smell.Materials and methods: We examined 145 patients aged 18–38 years who were diagnosed with changes in intranasal structures with varying degrees of nasal obstruction and impaired sense of smell. Patients were divided into 3 groups. The first group — patients with a disease duration of 3–5 years; the second group — patients with a disease duration of up to 0.5 years; the third group — patients with a disease duration of up to 1 month. Results: Patients with intranasal structures pathology in the I and III clinical groups with a duration of nasal obstruction up to 5 years and 1 month. Changes in systemic microcirculation were significantly more frequently observed than in patients with a disease duration of up to 0.5 years. The observed tendency to disturbance of microcirculation in groups III and I is caused, first of all, by a change in the state of microvessels for sharp hypoxia (these changes are consistent with rhinomanometry) and a “breakdown” of adaptation mechanisms in the group of prolonged nasal obstruction for up to 5 years, at that time as in group II, there is an increase in the reserve of adaptation from the cardiovascular system to the conditions of nasal obstruction. Сonclusions: The study of microcirculation using capillaroscopy made it possible to study the smallest vessels, capillaries, which are the first to respond to impaired nasal breathing by changing the functional state and morphological reconstruction of the microvasculature of the bloodstream.","PeriodicalId":33499,"journal":{"name":"Fotobiologiia ta fotomeditsina","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69001039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.26565/2076-0612-2019-26-02
The anti-inflammatory and antimicrobial effects of LED radiation on the oral mucosa when used in the combined treatment of prosthetic stomatitis were investigated. The test evidenced that the light radiation of Barva-Flex/BIR device (λ = 470 nm and λ = 940 nm) contributes to the reduction of inflammatory changes in oral mucosa and has a significant antimicrobial effect. LED radiation holds promise for use in the combined stomatitis treatment.
{"title":"Anti-inflammatory and antimicrobial effect of “Barva-Flex/BIR” device radiation in its application for prosthetic stomatitis treatment","authors":"","doi":"10.26565/2076-0612-2019-26-02","DOIUrl":"https://doi.org/10.26565/2076-0612-2019-26-02","url":null,"abstract":"The anti-inflammatory and antimicrobial effects of LED radiation on the oral mucosa when used in the combined treatment of prosthetic stomatitis were investigated. The test evidenced that the light radiation of Barva-Flex/BIR device (λ = 470 nm and λ = 940 nm) contributes to the reduction of inflammatory changes in oral mucosa and has a significant antimicrobial effect. LED radiation holds promise for use in the combined stomatitis treatment.","PeriodicalId":33499,"journal":{"name":"Fotobiologiia ta fotomeditsina","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69000519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.26565/2076-0612-2019-28-07
У Присутності, Метиленового Синього, П.А. Вірич, О.М. Надтока, Наталiя Куцевол, Богдан Криса
Introduction. Оpen wounds and ulcers treatment involves the use of bandage material, antibiotics and antiseptic to prevent the development of a pathogenic microflora and to provide the necessary conditions for tissue regeneration. An emergence of multi-resistant strains of microorganisms reduces the effectiveness of such technology and requires the new treatment approaches. One of the promising areas is a photodynamic therapy with the use of external photosensitizers. The aim of the investigation is to determine the effectiveness of the synergistic action of red light (660 nm) and different concentrations of methylene blue on the inhibition of Staphylococcus aureus growth. Materials and methods. We used the hydrogels based on the copolymers dextran-polyacrylamide with the different concentration of crosslinking agent 0.2 %, 0.4 %, 0.6 % (w/w) for investigation a rate of diffusion methylene blue into and out from hydrogel. Microbiological research was performed on wild strains of S. aureus isolated on a Yolk-salt agar. The evaluation of a bactericidal action of methylene blue was carried out on a Müller-Hinton No. 2 agar similarly to the disc-diffusion method for assessing the resistance of microorganisms to antibiotics. For irradiation by different wavelengths was used «LIKA-Led» (Photonics Plus) LEDs 390 nm, 460 nm and 660 nm. The radiation power for each wavelength was 100 mW, duration — 20 min, 30 min, 40 min. According to the duration, the irradiation doses were 21 J/cm2, 31.5 J/cm2, 42.1 J/cm2. Mathematical and statistical data processing was performed in the OriginLab 8.0 software package. Results. Increasing the amount of crosslinking agent in the hydrogel based on the copolymer dextran-polyacrylamide provides a decrease in the diffusion rate of methylene blue from the hydrogel. 390 nm ultraviolet radiation reduces the number of S. aureus colonies for 80% at 20 min exposure. Further increase in the exposure did not contribute to significant changes in this indicator. Blue light (460 nm) reduces the presence of this strain of microorganisms for 66% at 20 min exposure and reaches the effect of UV at 30 min exposure. Red light (660 nm) has no bactericidal effect. Minimal activity was found for methylene blue at concentrations of 0.001% and 0.0001% which was around 6 mm. The synergistic effect of 0.001% methylene blue and red light increases the activity for 40% up to 10 mm. Conclusions. For the photoinactivation of Staphylococcus aureus, it is advisable to use a low energy red light with a 660 nm wavelength in combination with a saturated methylene blue (0.001%) hydrogels. Perhaps the synergistic action of red light and dye provides a generation of active radicals that contribute to the growth retardation of microorganisms.
{"title":"Photoinactivation of staphylococcus aureus in vitro by red light (660 nm) in the presence of methylene blue","authors":"У Присутності, Метиленового Синього, П.А. Вірич, О.М. Надтока, Наталiя Куцевол, Богдан Криса","doi":"10.26565/2076-0612-2019-28-07","DOIUrl":"https://doi.org/10.26565/2076-0612-2019-28-07","url":null,"abstract":"Introduction. Оpen wounds and ulcers treatment involves the use of bandage material, antibiotics and antiseptic to prevent the development of a pathogenic microflora and to provide the necessary conditions for tissue regeneration. An emergence of multi-resistant strains of microorganisms reduces the effectiveness of such technology and requires the new treatment approaches. One of the promising areas is a photodynamic therapy with the use of external photosensitizers. The aim of the investigation is to determine the effectiveness of the synergistic action of red light (660 nm) and different concentrations of methylene blue on the inhibition of Staphylococcus aureus growth. Materials and methods. We used the hydrogels based on the copolymers dextran-polyacrylamide with the different concentration of crosslinking agent 0.2 %, 0.4 %, 0.6 % (w/w) for investigation a rate of diffusion methylene blue into and out from hydrogel. Microbiological research was performed on wild strains of S. aureus isolated on a Yolk-salt agar. The evaluation of a bactericidal action of methylene blue was carried out on a Müller-Hinton No. 2 agar similarly to the disc-diffusion method for assessing the resistance of microorganisms to antibiotics. For irradiation by different wavelengths was used «LIKA-Led» (Photonics Plus) LEDs 390 nm, 460 nm and 660 nm. The radiation power for each wavelength was 100 mW, duration — 20 min, 30 min, 40 min. According to the duration, the irradiation doses were 21 J/cm2, 31.5 J/cm2, 42.1 J/cm2. Mathematical and statistical data processing was performed in the OriginLab 8.0 software package. Results. Increasing the amount of crosslinking agent in the hydrogel based on the copolymer dextran-polyacrylamide provides a decrease in the diffusion rate of methylene blue from the hydrogel. 390 nm ultraviolet radiation reduces the number of S. aureus colonies for 80% at 20 min exposure. Further increase in the exposure did not contribute to significant changes in this indicator. Blue light (460 nm) reduces the presence of this strain of microorganisms for 66% at 20 min exposure and reaches the effect of UV at 30 min exposure. Red light (660 nm) has no bactericidal effect. Minimal activity was found for methylene blue at concentrations of 0.001% and 0.0001% which was around 6 mm. The synergistic effect of 0.001% methylene blue and red light increases the activity for 40% up to 10 mm. Conclusions. For the photoinactivation of Staphylococcus aureus, it is advisable to use a low energy red light with a 660 nm wavelength in combination with a saturated methylene blue (0.001%) hydrogels. Perhaps the synergistic action of red light and dye provides a generation of active radicals that contribute to the growth retardation of microorganisms.","PeriodicalId":33499,"journal":{"name":"Fotobiologiia ta fotomeditsina","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69001085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.26565/2076-0612-2019-26-12
Since the first demonstration of a tissue and organ transilluminator by a graduate of the Kyiv University V.A. Milliot at the 1867 exhibition in Paris, many enthusiasts have dealt with this diagnostic method. This paper provides an overview of publications from the funds of the Kharkiv Medical Library, materials from the Internet about the “transillumination” method, about Moshe Zelmanovich Sigal, educated at Donetsk Medical Institute, his life path, predecessors and followers. Studies in transmitted light are based on the differences in the absorption of light by various structures of the body. Transillumination attracts with the possibility of its use during operations. Depending on the relative position of the light source, the object being studied, and the researcher, three types of transillumination are possible: 1) intracavitary — the light source is inserted into the organ cavity; 2) transorgan — the light source is located behind the organ; and 3) extracavitary — transillumination is performed from the outside into the hollow organ when the imaging is made using an optical device inserted into the organ cavity. Inflation of a cavity increases the transparency of its walls and allows identifying subtler structures of the body. Based on transillumination angioscopy, M.Z. Sigal a half century ago developed a technique for lifetime monitoring of blood flow through the intramural vessels of the walls of hollow organs. Due to the difference in the color of blood in the vessels, the veins produce more intense shadow images than the arteries during transillumination. Transillumination angioscopy is possible without contrast agents. The development of technical means, the emergence of new light sources and its transportation allow modern surgeons to guide the course of the operation until the last suture using transillumination.
{"title":"Chapters of history of photomedicine: diagnostic transillumination in the XX-XXI centuries","authors":"","doi":"10.26565/2076-0612-2019-26-12","DOIUrl":"https://doi.org/10.26565/2076-0612-2019-26-12","url":null,"abstract":"Since the first demonstration of a tissue and organ transilluminator by a graduate of the Kyiv University V.A. Milliot at the 1867 exhibition in Paris, many enthusiasts have dealt with this diagnostic method. This paper provides an overview of publications from the funds of the Kharkiv Medical Library, materials from the Internet about the “transillumination” method, about Moshe Zelmanovich Sigal, educated at Donetsk Medical Institute, his life path, predecessors and followers. Studies in transmitted light are based on the differences in the absorption of light by various structures of the body. Transillumination attracts with the possibility of its use during operations. Depending on the relative position of the light source, the object being studied, and the researcher, three types of transillumination are possible: 1) intracavitary — the light source is inserted into the organ cavity; 2) transorgan — the light source is located behind the organ; and 3) extracavitary — transillumination is performed from the outside into the hollow organ when the imaging is made using an optical device inserted into the organ cavity. Inflation of a cavity increases the transparency of its walls and allows identifying subtler structures of the body. Based on transillumination angioscopy, M.Z. Sigal a half century ago developed a technique for lifetime monitoring of blood flow through the intramural vessels of the walls of hollow organs. Due to the difference in the color of blood in the vessels, the veins produce more intense shadow images than the arteries during transillumination. Transillumination angioscopy is possible without contrast agents. The development of technical means, the emergence of new light sources and its transportation allow modern surgeons to guide the course of the operation until the last suture using transillumination.","PeriodicalId":33499,"journal":{"name":"Fotobiologiia ta fotomeditsina","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69001134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.26565/2076-0612-2019-26-01
Y. Ivanova, E. Klimova, І. А. Krivoruchko, V. Prasol, D. A. Kirienko, A. Korobov, О. М. Клімова, І. А. Криворучко, О. Прасол, Д. О. Кірієнко, А. М. Коробов
The aim of the study was to improve the results of wound treatment in patients with ischemic and neuro-ischemic forms of diabetic foot syndrome through the use of phototherapy, platelet growth factor and modern coating materials in the treatment complex. The paper presents the results of surgical treatment of 48 patients with ischemic and neuroischemic diabetic foot syndrome, which, in accordance with the objectives of the study, were divided into two groups — the study (24 patients) and comparative (24 patients). All patients suffered from diabetes mellitus type II and had IV degree of foot ischemia according to Fontaine. The following reconstructive operations were performed in both groups of patients: femoral-tibialis and femoral-popliteal shunting, as well as hybrid reconstructions. In patients of the study group, the treatment technology developed by us was applied. Using the developed tactics, it was possible to achieve complete healing of wounds in 91,7 % of patients and partial healing (over 50 %) in 8.3 % of patients in the study group. The terms of treatment of these patients did not exceed 2 months, the execution of high amputations was not required.
{"title":"Tactic of treatment of ischemic diabetic foot syndrome","authors":"Y. Ivanova, E. Klimova, І. А. Krivoruchko, V. Prasol, D. A. Kirienko, A. Korobov, О. М. Клімова, І. А. Криворучко, О. Прасол, Д. О. Кірієнко, А. М. Коробов","doi":"10.26565/2076-0612-2019-26-01","DOIUrl":"https://doi.org/10.26565/2076-0612-2019-26-01","url":null,"abstract":"The aim of the study was to improve the results of wound treatment in patients with ischemic and neuro-ischemic forms of diabetic foot syndrome through the use of phototherapy, platelet growth factor and modern coating materials in the treatment complex. The paper presents the results of surgical treatment of 48 patients with ischemic and neuroischemic diabetic foot syndrome, which, in accordance with the objectives of the study, were divided into two groups — the study (24 patients) and comparative (24 patients). All patients suffered from diabetes mellitus type II and had IV degree of foot ischemia according to Fontaine. The following reconstructive operations were performed in both groups of patients: femoral-tibialis and femoral-popliteal shunting, as well as hybrid reconstructions. In patients of the study group, the treatment technology developed by us was applied. Using the developed tactics, it was possible to achieve complete healing of wounds in 91,7 % of patients and partial healing (over 50 %) in 8.3 % of patients in the study group. The terms of treatment of these patients did not exceed 2 months, the execution of high amputations was not required.","PeriodicalId":33499,"journal":{"name":"Fotobiologiia ta fotomeditsina","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69000498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.26565/2076-0612-2019-27-06
N. Kokodii, A. Korobov, H. Shi, M. F. Posokhov, S. Shulga, V. Timaniuk, Г. Кокодій, А. М. Коробов, Хе Ші, М. Ф. Посохов, С. М. Шульга
Introduction. Lasers in medicine are currently widely used for both diagnosis and treatment. Studies of the thermal processes that occur when a person is exposed to laser radiation have made it possible to developinnovative methods of treating many diseases. Purpose: to study thermal processes in biological tissues during their local laser heating (mathematical model and experiment). Materials and methods. Using the developed mathematical model of the process of local heating of a certain region inside biological tissue, we studied the process of heating the environment by continuous and pulsed laser radiation using infrared light with a wavelength of 0.98 μm, red light with a wavelength of 0.65 μm, green light with a wavelength 0.5 microns and blue light with a wavelength of 0.435 microns. Results. The sizes of the heated region, the time of establishment and decrease in temperature are determined. The calculation results are in good agreement with the obtained experimental data. Findings. The mode of heating biological tissue with laser radiation depends on the wavelength. The maximum heating temperature of the irradiated section with a radiation pulse duration much shorter than the thermal time constant is independent of the shape and duration of the pulse and is determined only by the energy of the absorbed radiation. The distribution of heat into the medium during the duration of the pulse is determined by its duration and thermal diffusivity of the tissue. To reduce the heating of the surrounding tissue, it is necessary to use short radiation pulses. The progress of tissue heating by a sequence of radiation pulses depends on the relationship between the duration of the pulses, the period of their repetition, and the thermal time constant of the medium. The average (smoothed) temperature is the same as when heated with continuous power equal to the average power of the pulse-modulated radiation.
{"title":"Thermal processes during local laser heating of biological tissues","authors":"N. Kokodii, A. Korobov, H. Shi, M. F. Posokhov, S. Shulga, V. Timaniuk, Г. Кокодій, А. М. Коробов, Хе Ші, М. Ф. Посохов, С. М. Шульга","doi":"10.26565/2076-0612-2019-27-06","DOIUrl":"https://doi.org/10.26565/2076-0612-2019-27-06","url":null,"abstract":"Introduction. Lasers in medicine are currently widely used for both diagnosis and treatment. Studies of the thermal processes that occur when a person is exposed to laser radiation have made it possible to developinnovative methods of treating many diseases. Purpose: to study thermal processes in biological tissues during their local laser heating (mathematical model and experiment). Materials and methods. Using the developed mathematical model of the process of local heating of a certain region inside biological tissue, we studied the process of heating the environment by continuous and pulsed laser radiation using infrared light with a wavelength of 0.98 μm, red light with a wavelength of 0.65 μm, green light with a wavelength 0.5 microns and blue light with a wavelength of 0.435 microns. Results. The sizes of the heated region, the time of establishment and decrease in temperature are determined. The calculation results are in good agreement with the obtained experimental data. Findings. The mode of heating biological tissue with laser radiation depends on the wavelength. The maximum heating temperature of the irradiated section with a radiation pulse duration much shorter than the thermal time constant is independent of the shape and duration of the pulse and is determined only by the energy of the absorbed radiation. The distribution of heat into the medium during the duration of the pulse is determined by its duration and thermal diffusivity of the tissue. To reduce the heating of the surrounding tissue, it is necessary to use short radiation pulses. The progress of tissue heating by a sequence of radiation pulses depends on the relationship between the duration of the pulses, the period of their repetition, and the thermal time constant of the medium. The average (smoothed) temperature is the same as when heated with continuous power equal to the average power of the pulse-modulated radiation.","PeriodicalId":33499,"journal":{"name":"Fotobiologiia ta fotomeditsina","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69000867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.26565/2076-0612-2019-26-03
V. Karandashov, N. Aleksandrova, E. I. Ostrovskiy, І. Карандашов, Нина Павловна Александрова, Є. І. Островський
The article presents the results of application of photochemotherapy in the complex rehabilitation process of patients with bronchial asthma (hereinafter — BA). The assessment of effectiveness and impact was made on the basis of changes in indicators of blood rheology as one of the pathogenesis of this disease and based on clinical indicators of the flow BA. It is established that in comparison with the results of the baseline treatment (42 patients) in 74 patients with BA under the influence of photochemotherapy occurs a statistically significant restoration of the altered rheological parameters and improves the clinical course of BA. The effect of optical radiation of blue and red lights on the clinical course of BA in comparison with conventional medication is more pronounced, almost the same criteria of treatment efficacy, but differ in their mechanism of effects on the body.
{"title":"Evaluation of the effectiveness of the application of quantum photohemotherapy red and blue light in the treatment of patients with bronchial asthma","authors":"V. Karandashov, N. Aleksandrova, E. I. Ostrovskiy, І. Карандашов, Нина Павловна Александрова, Є. І. Островський","doi":"10.26565/2076-0612-2019-26-03","DOIUrl":"https://doi.org/10.26565/2076-0612-2019-26-03","url":null,"abstract":"The article presents the results of application of photochemotherapy in the complex rehabilitation process of patients with bronchial asthma (hereinafter — BA). The assessment of effectiveness and impact was made on the basis of changes in indicators of blood rheology as one of the pathogenesis of this disease and based on clinical indicators of the flow BA. It is established that in comparison with the results of the baseline treatment (42 patients) in 74 patients with BA under the influence of photochemotherapy occurs a statistically significant restoration of the altered rheological parameters and improves the clinical course of BA. The effect of optical radiation of blue and red lights on the clinical course of BA in comparison with conventional medication is more pronounced, almost the same criteria of treatment efficacy, but differ in their mechanism of effects on the body.","PeriodicalId":33499,"journal":{"name":"Fotobiologiia ta fotomeditsina","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69000583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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