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Impact of pharmaceutical care for improving health-releated quality of life in patients with gastrointestinal pathology 药学服务对改善胃肠道病理患者健康相关生活质量的影响
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.11
Andra Ababei, Iuliana-Carmina Gherca, Adrian-Valerica Bobu, Maria Apotrosoaei
The gastrointestinal pathology is one of the most common health problems, with direct implications in reducing the patient's quality of life. The COVID-19 disease, which has become a global public health emergency since early 2020, affects both the respiratory and digestive systems. The profile of the gastrointestinal disorders, thus becomes much more complex, being able to indicate an early infection with the SARS-CoV-2 virus. In this context, the open-circuit pharmacy beyond the important role of treating patients, has active implications in the education and prevent program of spreading the SARS-CoV-2 virus, at least until the until the efficacy of the COVID-19 vaccine is demonstrated.
胃肠道病理学是最常见的健康问题之一,直接影响患者的生活质量。自2020年初以来,新冠肺炎已成为全球突发公共卫生事件,影响呼吸系统和消化系统。因此,胃肠道疾病的特征变得更加复杂,能够表明早期感染了严重急性呼吸系统综合征冠状病毒2型。在这种情况下,除了治疗患者的重要作用外,开放式药房对教育和预防SARS-CoV-2病毒传播计划具有积极影响,至少在新冠肺炎疫苗的有效性得到证明之前。
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引用次数: 0
Gastroesophageal reflux disease associatedsymptoms management in patients with chronic conditions 慢性胃食管反流病患者的相关症状管理
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.6
O. Ionescu, A. Popa, Teodora Hanghicel, L. Profire
Gastroesophageal reflux disease is a worldwide prevalent medical condition. It not only impacts the life quality of patients, but also plays a role in the socio-economic aspect in terms of management of symptoms and therapy. Attentive diagnosis is made after a physical examination that excludes other possible conditions such as cardiac or systemic diseases. Medication must be chosen in agreement with other underlying conditions (diabetes, autoimmune or rheumatic diseases etc.) as many interactions may occur otherwise. The role of a pharmacist plays a key role in this step. In the current situation of the pandemic, increased attention is necessary from the specialists´ point of view to fully benefit the patient.
胃食管反流病是一种世界范围内普遍存在的疾病。它不仅影响患者的生活质量,而且在症状管理和治疗方面也在社会经济方面发挥作用。仔细诊断是在排除心脏或全身疾病等其他可能疾病的体检后做出的。药物的选择必须与其他潜在疾病(糖尿病、自身免疫性或风湿性疾病等)相一致,否则可能会发生许多相互作用。药剂师的角色在这一步骤中起着关键作用。在当前的疫情形势下,从专家的角度来看,有必要增加关注,以使患者充分受益。
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引用次数: 0
Pharmacist’s recommendation and dispense of medication for gastrointestinal pathology according to national legislation 药师根据国家法规推荐和调配胃肠道病理药物
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.8
A. Munteanu, Alexandru Mandici, Daniel Cojocariu, A. Iacob
Pharmacist’s role in community pharmacy is to provide counselling for patients with disorders accompanied by mild symptoms that do not require medical consultation, but also is to recommend a referral to a physician when the severity of the situation requires it. The pharmacist also performs counselling regarding posology of the prescribed medicines, and informs patients about potential side effects that may occur. Gastrointestinal disorders are widespread among the population and pharmacists have the role and the responsibility to use their knowledge to dispense appropriate medicines according to every patient’s needs, in compliance with the legislation and recommendations of ANMDM.
药剂师在社区药房的作用是为不需要医疗咨询的症状轻微的疾病患者提供咨询,但当情况严重需要时,也建议转诊给医生。药剂师还就处方药物的药理进行咨询,并告知患者可能发生的潜在副作用。胃肠道疾病在人群中很普遍,药剂师有作用和责任利用他们的知识,根据每个病人的需要,按照国家药品监督管理委员会的立法和建议,分配适当的药物。
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引用次数: 0
The role of the pharmacist in the prevention of gastrointestinal diseases 药剂师在预防胃肠道疾病中的作用
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.1
F. Lupașcu, L. Herciu, Simona Tătărușanu, I. Vasincu, L. Profire
Pharmacists are health care professionals and their role is to provide health services, recommendations and support to all type of patients with a diversity of pathologies, including gastrointestinal diseases. In the last years, in countries where previously some gastrointestinal diseases were not so common, nowadays are augmenting, for example Crohn’s disease. In some country as Asia, Africa and Eastern Europe the number of patients with this type of diseases is constantly growing. Considering its high incidence, physical, mental and economic impact, it is vital to prevent as much as possible its apparition. High risk factors are represented by inadequate diet and lifestyle, medication side effects, drugs interactions or administration and dosage errors. The aim of this paper is to analyze the important role of pharmacists in preventing some gastrointestinal effects by offering correct information and advices to patients. This paper includes information related to self-medication, over-the-counter medication, side effects and the importance of microbial flora, equilibrate diet and lifestyle.
药剂师是医疗保健专业人员,他们的职责是为包括胃肠道疾病在内的各种疾病的所有类型的患者提供医疗服务、建议和支持。在过去的几年里,在以前一些胃肠道疾病不那么常见的国家,现在正在加剧,例如克罗恩病。在亚洲、非洲和东欧等一些国家,这类疾病的患者数量不断增长。考虑到它的高发病率、身体、精神和经济影响,尽可能防止它的出现至关重要。高风险因素表现为饮食和生活方式不足、药物副作用、药物相互作用或给药和剂量错误。本文旨在通过向患者提供正确的信息和建议,分析药剂师在预防某些胃肠道影响方面的重要作用。本文包括与自我用药、非处方药、副作用和微生物菌群的重要性、平衡饮食和生活方式有关的信息。
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引用次数: 0
Pharmacist-doctor collaboration during the pandemic, effective management of gastrointestinal pathology 大流行期间药师-医生合作,有效管理胃肠道病理
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.7
Alexandru Mandici, A. Munteanu, Daniel Cojocariu, A. Iacob
The novel coronavirus SARS-CoV-2 is responsible for the emergence of a potentially life-threatening disease (COVID-19) which has put tremendous pressure on the healthcare systems worldwide. Pharmacists, either from hospital or community pharmacies, are playing an essential role in the management of current COVID-19 pandemic as trustworthy partners of physicians, contributing to the reduction of drug-induced adverse events through medication guidance, thereby improving patient compliance and helping them regaining their confidence to overcome the disease. In the management of gastrointestinal symptoms that may or may not be in the context of COVID-19, pharmacists should recommend that patients consult a physician when gastrointestinal pathology is complex and associated with other symptoms.
新型冠状病毒SARS-CoV-2导致了一种可能危及生命的疾病(COVID-19)的出现,给全球卫生保健系统带来了巨大压力。医院或社区药房的药剂师作为医生可信赖的合作伙伴,在当前COVID-19大流行的管理中发挥着至关重要的作用,通过用药指导,有助于减少药物引起的不良事件,从而提高患者的依从性,帮助他们恢复战胜疾病的信心。在处理可能与COVID-19无关的胃肠道症状时,药师应建议患者在胃肠道病理复杂并伴有其他症状时咨询医生。
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引用次数: 0
Drug interactions in gastrointestinal disorders therapy 胃肠道疾病治疗中的药物相互作用
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.5
A. Focșa, A. Sava, Andra Ababei, Maria Apotrosoaei
Drug-drug interactions are a major cause of adverse reactions in polypharmacy, the incidence being directly proportional to the number of associated drugs. In this work, we highlighted the main drug-drug interactions that occurred in the treatment of gastrointestinal symptoms with proton pump inhibitors and histamine H2-receptor antagonists. The two groups of agents, used in gastroesophageal reflux and ulcer disease, can be released and without a prescription on the recommendation of the pharmacist, contributing to the risk of emergence of drug-drug interactions. Drug-drug interactions can occur due to the reduction of the gastric acidity, altering the biotransformation or excretion reducing of the drug co-administrated. pH increased may affect the absorption of some drugs decreasing (e.g. ketoconazole, itraconazole, atazanavir, vitamin B12, magnesium) or increasing the absorption of others (e.g. triazolam, midazolam). Furthermore, an attention to the interaction with narrow therapeutic index drugs (e.g. warfarin, phenytoin, theophylline) is required because of the risk of the toxic or side effects by the accumulation of these drugs.
药物相互作用是多种药物不良反应的主要原因,其发生率与相关药物的数量成正比。在这项工作中,我们强调了质子泵抑制剂和组胺H2受体拮抗剂治疗胃肠道症状时发生的主要药物相互作用。这两组药物用于胃食管反流和溃疡病,在药剂师的建议下,无需处方即可释放,这会增加药物相互作用的风险。药物与药物的相互作用可能是由于胃酸减少,改变了共同给药的生物转化或排泄减少。pH值升高可能会影响某些药物的吸收,例如酮康唑、伊曲康唑、阿扎那韦、维生素B12、镁)或增加其他药物的吸收(例如三唑仑、咪达唑仑)。此外,需要注意与窄治疗指数药物(如华法林、苯妥英钠、茶碱)的相互作用,因为这些药物的积累有毒性或副作用的风险。
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引用次数: 1
Ethics in patient counseling and pharmaceutical practice by emotions management 情绪管理在患者咨询和药物实践中的伦理
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.9
Alexandru-Vasile Sava, E. Sava, A. Panainte, A. Focșa, N. Bibire
Effective communication is an essential part of pharmacy practice aimed to ensured counsel patients about their prescribed medicines. This will lead to a rational use of medicine with an improved therapeutic outcome, increasing compliance and decreasing confusion and insecurity. For the purpose of legal regulation of pharmacist-patient communication, professional associations from different countries have developed the codes of ethics for pharmacists. As in other countries, the Code of Ethics of Pharmacists in Romania and Law 81/1997 guarantee respect for the rights and dignity of the patient. Communication is a highly complex area and ability to understand a patient’s feelings could be the key to ensuring high-quality interactions. Developing that relationship can mean addressing patients’ emotional responses to therapy, as well as acknowledging their concerns or frustrations. Through careful analysis of the communication in pharmaceutical practice we can help develop skills, tools and processes to make patient encounters as optimal as possible. This paper analyses some tools to understand a patient’s feelings that could be the key to ensuring high-quality interactions.
有效的沟通是药学实践的重要组成部分,旨在确保为患者提供处方药方面的咨询。这将导致合理用药,改善治疗效果,提高依从性,减少混乱和不安全感。为了对药剂师与患者的沟通进行法律规范,来自不同国家的专业协会制定了药剂师道德规范。与其他国家一样,罗马尼亚的《药剂师道德守则》和第81/1997号法律保障尊重病人的权利和尊严。沟通是一个高度复杂的领域,理解患者感受的能力可能是确保高质量互动的关键。发展这种关系可能意味着解决患者对治疗的情绪反应,以及承认他们的担忧或沮丧。通过对制药实践中的沟通进行仔细分析,我们可以帮助开发技能、工具和流程,使患者尽可能地获得最佳体验。本文分析了一些理解患者感受的工具,这些工具可能是确保高质量互动的关键。
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引用次数: 0
The symptomatology of the gastroesophageal reflux disease and the first line therapy 胃食管反流病的症状学及一线治疗
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.3
Teodora Hanghicel, Emanuela Strugaru, O. Ionescu, L. Profire
Over time, gastroesophageal reflux has undergone an unexpected and at the same time undesirable evolution towards the most commonly diagnosed upper gastrointestinal disease, called gastroesophageal reflux disease. The symptoms of gastroesophageal reflux disease are complex, difficult to treat and often recurrent. In order to prevent the disease recurrences, it is also necessary to establish the treatment in accordance with the gastroesophageal reflux symptoms. Unfortunately, nowadays, more and more patients of all ages go to the pharmacy with typical symptoms of gastroesophageal reflux, this ailment having a negative impact on the quality of life. This article aims to highlight the role of the pharmacist in recognizing the symptoms of gastroesophageal reflux and initiating firstline treatment.
随着时间的推移,胃食管反流发生了一种意想不到的、同时也是不可取的演变,成为最常见的上消化道疾病,称为胃食管反流病。胃食管反流病的症状复杂,难以治疗,经常复发。为了防止疾病复发,还需要根据胃食管反流症状制定治疗方法。不幸的是,如今,越来越多的各个年龄段的患者带着典型的胃食管反流症状去药店,这种疾病对生活质量产生了负面影响。本文旨在强调药剂师在识别胃食管反流症状和启动一线治疗方面的作用。
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引用次数: 0
Counseling a patient presenting gastrointestinal symptoms in the circumstances of a limited range of available medication – social aspects 在可用药物范围有限的情况下为出现胃肠道症状的患者提供咨询——社会方面
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.10
A. Grigorescu, M. Marcu, B. Profire, L. Profire
The health and illness concepts have a major significance for both the patient and the healthcare specialists. Therefore, the role of the pharmacist is an extremely important one and, during the pandemic times, the relationship between the pharmacist and the patient has further expanded. The healthcare specialist should personalize the medical treatment plan for each individual patient, in order to obtain maximum efficiency with the lowest possible risk. Approximately 20% of all patients infected with SARS-CoV-2 present gastrointestinal symptoms, such as loss of appetite, nausea, vomiting or generalized abdominal pain. Any treatment recommendation made by the pharmacist should take into consideration general aspects regarding the intensity and the localization of the pain, as well as any chronic or acute treatment that the patient may undergo, all relevant medical history and the immediate prognosis of the disease.
健康和疾病概念对患者和医疗保健专家都具有重要意义。因此,药剂师的作用极其重要,在疫情期间,药剂师和患者之间的关系进一步扩大。医疗保健专家应为每位患者制定个性化的医疗计划,以便以尽可能低的风险获得最大的效率。大约20%的感染严重急性呼吸系统综合征冠状病毒2型的患者出现胃肠道症状,如食欲不振、恶心、呕吐或全身腹痛。药剂师提出的任何治疗建议都应考虑到疼痛强度和定位的一般方面,以及患者可能接受的任何慢性或急性治疗,所有相关病史和疾病的即时预后。
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引用次数: 0
Therapeutic management of gastrointestinal disorders 胃肠道疾病的治疗管理
Pub Date : 2021-07-30 DOI: 10.37897/rjphp.2021.s.4
M. Dragan, R. Stan, O. Dragostin, C. Stan
Chronic gastrointestinal disorders are becoming more widespread among the population, therefore physicians and pharmacists are meant to use their knowledge and deliver appropriate treatments according to the needs of each patient, relying on new research results and medical practice acquisitions. Common chronic gastrointestinal disorders are: gastroesophageal reflux disease, dyspepsia, irritable bowel syndrome, coeliac disease, inflammatory bowel disease, with a growing global incidence and prevalence, especially in Western countries, being closely linked to socio-economic progress. The effect of patient counseling is seen in improving the patient`s quality of life. As part of medication therapy management, patient counseling focusing on compliance, diet and medications is an effective tool to improve health-related. Such services improve outcomes in chronic gastrointestinal disorders.
慢性胃肠疾病在人群中变得越来越普遍,因此医生和药剂师应该利用他们的知识,根据每个病人的需要,依靠新的研究成果和医疗实践的获得,提供适当的治疗。常见的慢性胃肠道疾病有:胃食管反流病、消化不良、肠易激综合征、乳糜泻、炎症性肠病,全球发病率和患病率不断上升,特别是在西方国家,与社会经济进步密切相关。患者咨询的效果体现在患者生活质量的提高上。作为药物治疗管理的一部分,以依从性、饮食和药物为重点的患者咨询是改善健康相关的有效工具。这些服务改善了慢性胃肠疾病的治疗效果。
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引用次数: 0
期刊
Practica Farmaceutica
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